Harvard Catalyst Profiles

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Pavan K Bendapudi, M.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21HL153655 (BENDAPUDI, PAVAN) Sep 1, 2020 - Jul 31, 2022
    Elucidating the Role of Inherited Complement System Defects in the Molecular Pathophysiology of Sepsis and Purpura Fulminans
    Role: Principal Investigator
  2. 1K08HL136840 (Bendapudi) Jul 1, 2017 - Jun 30, 2022
    The Role of Coagulation Factor XII in Hemostasis and Thrombosis
  3. K08HL136840 (BENDAPUDI, PAVAN) Jul 1, 2017 - Jun 30, 2022
    The Role of Coagulation Factor XII in Hemostasis and Thrombosis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Goshua G, Bendapudi PK, Lee AI. Thrombosis questions from the inpatient wards. Hematology Am Soc Hematol Educ Program. 2022 12 09; 2022(1):481-490. PMID: 36485139; PMCID: PMC9819989.
    Citations:    Fields:    Translation:Humans
  2. Goshua G, Bendapudi PK. Evidence-Based Minireview: Should caplacizumab be used routinely in unselected patients with immune thrombotic thrombocytopenic purpura? Hematology Am Soc Hematol Educ Program. 2022 12 09; 2022(1):491-494. PMID: 36485149; PMCID: PMC9820987.
    Citations:    Fields:    Translation:Humans
  3. Bouzinier MA, Etin D, Trifonov SI, Evdokimova VN, Ulitin V, Shen J, Kokorev A, Ghazani AA, Chekaluk Y, Albertyn Z, Giersch A, Morton CC, Abraamyan F, Bendapudi PK, Sunyaev S, Krier JB. AnFiSA: An open-source computational platform for the analysis of sequencing data for rare genetic disease. J Biomed Inform. 2022 09; 133:104174. PMID: 35998814.
    Citations:    Fields:    
  4. Versluis J, Pandey M, Flamand Y, Haydu JE, Belizaire R, Faber M, Vedula RS, Charles A, Copson KM, Shimony S, Rozental A, Bendapudi PK, Wolach O, Griffiths EA, Thompson JE, Stone RM, DeAngelo DJ, Neuberg D, Luskin MR, Wang ES, Lindsley RC. Prediction of life-threatening and disabling bleeding in patients with AML receiving intensive induction chemotherapy. Blood Adv. 2022 05 10; 6(9):2835-2846. PMID: 35081257; PMCID: PMC9092400.
    Citations:    Fields:    Translation:Humans
  5. Gadi SRV, Brunker PAR, Al-Samkari H, Sykes DB, Saff RR, Lo J, Bendapudi P, Leaf DE, Leaf RK. Severe autoimmune hemolytic anemia following receipt of SARS-CoV-2 mRNA vaccine. Transfusion. 2021 11; 61(11):3267-3271. PMID: 34549821.
    Citations: 5     Fields:    Translation:HumansCells
  6. Goshua G, Prasad V, Lee AI, Bendapudi PK. Accurate accounting of caplacizumab cost effectiveness. Lancet Haematol. 2021 05; 8(5):e315. PMID: 33894166.
    Citations:    Fields:    Translation:Humans
  7. Bendapudi PK, Whalen MJ, Lahoud-Rahme M, Villalba JA. Case 7-2021: A 19-Year-Old Man with Shock, Multiple Organ Failure, and Rash. N Engl J Med. 2021 03 11; 384(10):953-963. PMID: 33704941.
    Citations: 1     Fields:    Translation:HumansCells
  8. Goshua G, Sinha P, Hendrickson JE, Tormey C, Bendapudi PK, Lee AI. Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura. Blood. 2021 02 18; 137(7):969-976. PMID: 33280030; PMCID: PMC7918179.
    Citations: 11     Fields:    Translation:Humans
  9. Fitzsimons MG, Barrett C, Streckenbach S, Bendapudi PK. Factor V Deficiency (Owren's Disease) in a Patient at High Risk for Transfusion-Associated Circulatory Overload and Bleeding During Laser Lead Extraction. J Cardiothorac Vasc Anesth. 2022 01; 36(1):242-245. PMID: 33744111.
    Citations:    Fields:    Translation:Humans
  10. Grover SP, Bendapudi PK, Yang M, Merrill-Skoloff G, Govindarajan V, Mitrophanov AY, Flaumenhaft R. Injury measurements improve interpretation of thrombus formation data in the cremaster arteriole laser-induced injury model of thrombosis. J Thromb Haemost. 2020 11; 18(11):3078-3085. PMID: 33456401.
    Citations: 4     Fields:    Translation:AnimalsCells
  11. Chaudhry SA, Serrata M, Tomczak L, Higgins S, Ryu J, Laprise D, Enjyoji K, Bekendam R, Kaushik V, Flaumenhaft R, Bendapudi PK. Cationic zinc is required for factor XII recruitment and activation by stimulated platelets and for thrombus formation in vivo. J Thromb Haemost. 2020 09; 18(9):2318-2328. PMID: 32542960.
    Citations: 3     Fields:    Translation:AnimalsCells
  12. Al-Samkari H, Karp Leaf RS, Dzik WH, Carlson JCT, Fogerty AE, Waheed A, Goodarzi K, Bendapudi PK, Bornikova L, Gupta S, Leaf DE, Kuter DJ, Rosovsky RP. COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection. Blood. 2020 07 23; 136(4):489-500. PMID: 32492712; PMCID: PMC7378457.
    Citations: 447     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  13. Makar RS, Bendapudi PK. Assessing the risk of refractory disease in iTTP. Br J Haematol. 2020 10; 191(2):143-144. PMID: 32656761.
    Citations:    Fields:    Translation:Humans
  14. Soffer MD, Bendapudi PK, Roberts DJ, Edelson PK, Kuter DJ, Ecker JL, Bryant A, Goldfarb IT. Congenital thrombotic thrombocytopenic purpura (TTP) with placental abruption despite maternal improvement: a case report. BMC Pregnancy Childbirth. 2020 Jun 15; 20(1):365. PMID: 32539690.
    Citations:    Fields:    Translation:Humans
  15. Al-Samkari H, Leiva O, Dagogo-Jack I, Shaw A, Lennerz J, Iafrate AJ, Bendapudi PK, Connors JM. Impact of ALK Rearrangement on Venous and Arterial Thrombotic Risk in NSCLC. J Thorac Oncol. 2020 09; 15(9):1497-1506. PMID: 32437899.
    Citations: 11     Fields:    Translation:Humans
  16. Colling M, Sun L, Upadhyay V, Ryu J, Li A, Uhl L, Kaufman RM, Stowell CP, Dzik WH, Makar RS, Bendapudi PK. Deaths and complications associated with the management of acute immune thrombotic thrombocytopenic purpura. Transfusion. 2020 04; 60(4):841-846. PMID: 32080877.
    Citations: 2     Fields:    Translation:Humans
  17. Upadhyay VA, Geisler BP, Sun L, Uhl L, Kaufman RM, Stowell C, Makar RS, Bendapudi PK. Utilizing a PLASMIC score-based approach in the management of suspected immune thrombotic thrombocytopenic purpura: a cost minimization analysis within the Harvard TMA Research Collaborative. Br J Haematol. 2019 08; 186(3):490-498. PMID: 31131442; PMCID: PMC6642029.
    Citations: 4     Fields:    Translation:Humans
  18. Sun L, Mack J, Li A, Ryu J, Upadhyay VA, Uhl L, Kaufman RM, Stowell CP, Dzik WS, Makar RS, Bendapudi PK. Predictors of relapse and efficacy of rituximab in immune thrombotic thrombocytopenic purpura. Blood Adv. 2019 05 14; 3(9):1512-1518. PMID: 31076407; PMCID: PMC6517661.
    Citations: 5     Fields:    Translation:Humans
  19. Bendapudi PK, Robbins A, LeBoeuf N, Pozdnyakova O, Bhatt A, Duke F, Sells R, McQuiston J, Humrighouse B, Rouaisnel B, Colling M, Stephenson KE, Saavedra A, Losman JA. Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate. Blood Adv. 2018 11 13; 2(21):2917-2921. PMID: 30396911.
    Citations: 2     Fields:    Translation:HumansCells
  20. Bekendam RH, Iyu D, Passam F, Stopa JD, De Ceunynck K, Muse O, Bendapudi PK, Garnier CL, Gopal S, Crescence L, Chiu J, Furie B, Panicot-Dubois L, Hogg PJ, Dubois C, Flaumenhaft R. Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation. J Thromb Haemost. 2018 11; 16(11):2322-2335. PMID: 30207066.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  21. Fitzsimons MG, Leaf RK, Mack J, Bendapudi PK, Shen T, Cameron DE. Perioperative management of a redo aortic root replacement in a patient with severe factor XI deficiency. J Card Surg. 2018 Feb; 33(2):86-89. PMID: 29399875.
    Citations: 2     Fields:    Translation:Humans
  22. Colling ME, Bendapudi PK. Purpura Fulminans: Mechanism and Management of Dysregulated Hemostasis. Transfus Med Rev. 2018 04; 32(2):69-76. PMID: 29157918.
    Citations: 18     Fields:    Translation:Humans
  23. Li A, Bendapudi PK, Uhl L, Hamdan A, Kaufman RM, Makar RS. Clinical features and outcomes in patients with thrombotic microangiopathy not associated with severe ADAMTS13 deficiency. Transfusion. 2017 09; 57(9):2151-2158. PMID: 28635017.
    Citations: 2     Fields:    Translation:Humans
  24. Bendapudi PK, Upadhyay V, Sun L, Marques MB, Makar RS. Clinical Scoring Systems in Thrombotic Microangiopathies. Semin Thromb Hemost. 2017 Jul; 43(5):540-548. PMID: 28597458.
    Citations: 8     Fields:    Translation:Humans
  25. Bendapudi PK, Hurwitz S, Fry A, Marques MB, Waldo SW, Li A, Sun L, Upadhyay V, Hamdan A, Brunner AM, Gansner JM, Viswanathan S, Kaufman RM, Uhl L, Stowell CP, Dzik WH, Makar RS. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study. Lancet Haematol. 2017 Apr; 4(4):e157-e164. PMID: 28259520.
    Citations: 99     Fields:    Translation:Humans
  26. Frydman GH, Marini RP, Bakthavatchalu V, Biddle KE, Muthupalani S, Vanderburg CR, Lai B, Bendapudi PK, Tompkins RG, Fox JG. Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta). Comp Med. 2017 Mar 01; 67(2):165-175. PMID: 28381317; PMCID: PMC5402736.
    Citations: 4     Fields:    Translation:Animals
  27. Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. A substrate-driven allosteric switch that enhances PDI catalytic activity. Nat Commun. 2016 08 30; 7:12579. PMID: 27573496.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  28. Bendapudi P. Bench to bedside: the challenge and promise of translating basic research discoveries in thrombotic microangiopathies. Transfusion. 2016 07; 56(7):1675-7. PMID: 27389992.
    Citations:    Fields:    Translation:Humans
  29. Li A, Makar RS, Hurwitz S, Uhl L, Kaufman RM, Stowell CP, Dzik WS, Bendapudi PK. Treatment with or without plasma exchange for patients with acquired thrombotic microangiopathy not associated with severe ADAMTS13 deficiency: a propensity score-matched study. Transfusion. 2016 08; 56(8):2069-77. PMID: 27232383.
    Citations: 9     Fields:    Translation:Humans
  30. Bendapudi PK, Makar RS. An Algorithmic Approach to the Diagnosis and Management of the Thrombotic Microangiopathies. Am J Clin Pathol. 2016 02; 145(2):152-4. PMID: 26864515.
    Citations: 3     Fields:    Translation:Humans
  31. Frydman GH, Bendapudi PK, Marini RP, Vanderburg CR, Tompkins RG, Fox JG. Coagulation Biomarkers in Healthy Chinese-Origin Rhesus Macaques (Macaca mulatta). J Am Assoc Lab Anim Sci. 2016; 55(3):252-9. PMID: 27177557; PMCID: PMC4865685.
    Citations: 1     Fields:    Translation:Animals
  32. Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal. 2016 Jan 01; 24(1):1-15. PMID: 26467859; PMCID: PMC4717499.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  33. Bendapudi PK, Li A, Hamdan A, Uhl L, Kaufman R, Stowell C, Dzik W, Makar RS. Impact of severe ADAMTS13 deficiency on clinical presentation and outcomes in patients with thrombotic microangiopathies: the experience of the Harvard TMA Research Collaborative. Br J Haematol. 2015 Dec; 171(5):836-44. PMID: 26314936.
    Citations: 23     Fields:    Translation:Humans
  34. Tran PT, Bendapudi PK, Lin HJ, Choi P, Koh S, Chen J, Horng G, Hughes NP, Schwartz LH, Miller VA, Kawashima T, Kitamura T, Paik D, Felsher DW. Survival and death signals can predict tumor response to therapy after oncogene inactivation. Sci Transl Med. 2011 Oct 05; 3(103):103ra99. PMID: 21974937.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  35. Arvanitis C, Bendapudi PK, Tseng JR, Gambhir SS, Felsher DW. (18)F and (18)FDG PET imaging of osteosarcoma to non-invasively monitor in situ changes in cellular proliferation and bone differentiation upon MYC inactivation. Cancer Biol Ther. 2008 Dec; 7(12):1947-51. PMID: 18981708; PMCID: PMC4158945.
    Citations: 6     Fields:    Translation:HumansAnimals
  36. Tran PT, Fan AC, Bendapudi PK, Koh S, Komatsubara K, Chen J, Horng G, Bellovin DI, Giuriato S, Wang CS, Whitsett JA, Felsher DW. Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas. PLoS One. 2008 May 07; 3(5):e2125. PMID: 18461184.
    Citations: 49     Fields:    Translation:HumansAnimals
  37. Tran PT, Hara W, Su Z, Lin HJ, Bendapudi PK, Norton J, Teng N, King CR, Kapp DS. Intraoperative radiation therapy for locally advanced and recurrent soft-tissue sarcomas in adults. Int J Radiat Oncol Biol Phys. 2008 Nov 15; 72(4):1146-53. PMID: 18394818.
    Citations: 7     Fields:    Translation:Humans
  38. Arvanitis C, Bendapudi PK, Bachireddy P, Felsher DW. Identifying critical signaling molecules for the treatment of cancer. Recent Results Cancer Res. 2007; 172:5-24. PMID: 17607933.
    Citations: 1     Fields:    Translation:AnimalsCells
  39. Bachireddy P, Bendapudi PK, Felsher DW. Getting at MYC through RAS. Clin Cancer Res. 2005 Jun 15; 11(12):4278-81. PMID: 15958607.
    Citations: 16     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.