Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Stanley Shaw, Ph.D., M.D.

Other Positions

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL131015 (SHAW, STANLEY Y) Jan 1, 2016 - Dec 31, 2020
    Clinical, genetic and cardiometabolic risk correlates of the gut microbiome
    Role: Co-Principal Investigator
  2. U19AI109725 (VIRGIN, HERBERT W) Mar 1, 2014 - Feb 28, 2019
    Autophagy Modulators as Novel Broad-Spectrum Anti-Infective Agents
    Role: Co-Principal Investigator
  3. K08HL077186 (SHAW, STANLEY Y) Jul 1, 2004 - Aug 31, 2009
    Chemical Genetic Studies of Vascular Development
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Walker RL, Vlamakis H, Lee JWJ, Besse LA, Xanthakis V, Vasan RS, Shaw SY, Xavier RJ. Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease. Genome Med. 2021 12 17; 13(1):188. PMID: 34915914; PMCID: PMC8680346.
    Citations: 2     Fields:    Translation:Humans
  2. MacRae CA, Deo RC, Shaw SY. Ecosystem Barriers to Innovation Adoption in Clinical Practice. Trends Mol Med. 2021 01; 27(1):5-7. PMID: 33293198.
    Citations:    Fields:    Translation:Humans
  3. Kenny DJ, Plichta DR, Shungin D, Koppel N, Hall AB, Fu B, Vasan RS, Shaw SY, Vlamakis H, Balskus EP, Xavier RJ. Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level. Cell Host Microbe. 2020 08 12; 28(2):245-257.e6. PMID: 32544460; PMCID: PMC7435688.
    Citations: 44     Fields:    Translation:HumansCells
  4. Zhang Y, Cai T, Yu S, Cho K, Hong C, Sun J, Huang J, Ho YL, Ananthakrishnan AN, Xia Z, Shaw SY, Gainer V, Castro V, Link N, Honerlaw J, Huang S, Gagnon D, Karlson EW, Plenge RM, Szolovits P, Savova G, Churchill S, O'Donnell C, Murphy SN, Gaziano JM, Kohane I, Cai T, Liao KP. High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP). Nat Protoc. 2019 12; 14(12):3426-3444. PMID: 31748751; PMCID: PMC7323894.
    Citations: 31     Fields:    Translation:Humans
  5. Kartoun U, Iglay K, Shankar RR, Beam A, Radican L, Chatterjee A, Pai JK, Shaw S. Factors associated with clinical inertia in type 2 diabetes mellitus patients treated with metformin monotherapy. Curr Med Res Opin. 2019 12; 35(12):2063-2070. PMID: 31337263.
    Citations: 1     Fields:    Translation:Humans
  6. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Savova G, Shaw SY, Churchill S, Burke KE, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Use of Narrative Concepts in Electronic Health Records to Validate Associations Between Genetic Factors and Response to Treatment of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2020 07; 18(8):1890-1892. PMID: 31404664.
    Citations: 1     Fields:    Translation:Humans
  7. Kartoun U, Aggarwal R, Beam AL, Pai JK, Chatterjee AK, Fitzgerald TP, Kohane IS, Shaw SY. Development of an Algorithm to Identify Patients with Physician-Documented Insomnia. Sci Rep. 2018 05 18; 8(1):7862. PMID: 29777125.
    Citations: 5     Fields:    Translation:Humans
  8. Kartoun U, Corey KE, Simon TG, Zheng H, Aggarwal R, Ng K, Shaw SY. The MELD-Plus: A generalizable prediction risk score in cirrhosis. PLoS One. 2017; 12(10):e0186301. PMID: 29069090.
    Citations: 14     Fields:    Translation:Humans
  9. Simon TG, Kartoun U, Zheng H, Chan AT, Chung RT, Shaw S, Corey KE. MELD-Na score predicts incident major cardiovascular events, in patients with nonalcoholic fatty liver disease (NAFLD). Hepatol Commun. 2017 Jul; 1(5):429-438. PMID: 29085919.
    Citations: 2     Fields:    
  10. Beam AL, Kartoun U, Pai JK, Chatterjee AK, Fitzgerald TP, Shaw SY, Kohane IS. Predictive Modeling of Physician-Patient Dynamics That Influence Sleep Medication Prescriptions and Clinical Decision-Making. Sci Rep. 2017 02 09; 7:42282. PMID: 28181568.
    Citations: 9     Fields:    Translation:Humans
  11. Dorsey ER, Yvonne Chan YF, McConnell MV, Shaw SY, Trister AD, Friend SH. The Use of Smartphones for Health Research. Acad Med. 2017 02; 92(2):157-160. PMID: 27119325.
    Citations: 71     Fields:    Translation:Humans
  12. Secemsky EA, Butala NM, Kartoun U, Mahmood S, Wasfy JH, Kennedy KF, Shaw SY, Yeh RW. Use of Chronic Oral Anticoagulation and Associated Outcomes Among Patients Undergoing Percutaneous Coronary Intervention. J Am Heart Assoc. 2016 10 17; 5(10). PMID: 27792650.
    Citations: 6     Fields:    Translation:Humans
  13. Vafai SB, Mevers E, Higgins KW, Fomina Y, Zhang J, Mandinova A, Newman D, Shaw SY, Clardy J, Mootha VK. Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors. PLoS One. 2016; 11(9):e0162686. PMID: 27622560.
    Citations: 12     Fields:    Translation:AnimalsCells
  14. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN. Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2016 Apr; 22(4):880-5. PMID: 26933751; PMCID: PMC4792716.
    Citations: 14     Fields:    Translation:Humans
  15. Hall JL, Ryan JJ, Bray BE, Brown C, Lanfear D, Newby LK, Relling MV, Risch NJ, Roden DM, Shaw SY, Tcheng JE, Tenenbaum J, Wang TN, Weintraub WS. Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association. Circ Cardiovasc Genet. 2016 Apr; 9(2):193-202. PMID: 26976545.
    Citations: 11     Fields:    Translation:Humans
  16. Corey KE, Kartoun U, Zheng H, Chung RT, Shaw SY. Using an Electronic Medical Records Database to Identify Non-Traditional Cardiovascular Risk Factors in Nonalcoholic Fatty Liver Disease. Am J Gastroenterol. 2016 05; 111(5):671-6. PMID: 26925881; PMCID: PMC4864030.
    Citations: 10     Fields:    Translation:Humans
  17. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2016 07; 14(7):973-9. PMID: 26905907; PMCID: PMC4912917.
    Citations: 25     Fields:    Translation:Humans
  18. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort. Inflamm Bowel Dis. 2016 Jan; 22(1):151-8. PMID: 26332313; PMCID: PMC4772891.
    Citations: 9     Fields:    Translation:Humans
  19. Corey KE, Kartoun U, Zheng H, Shaw SY. Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record. Dig Dis Sci. 2016 Mar; 61(3):913-9. PMID: 26537487; PMCID: PMC4761309.
    Citations: 25     Fields:    Translation:Humans
  20. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015 Nov; 21(11):2507-14. PMID: 26241000; PMCID: PMC4615315.
    Citations: 10     Fields:    Translation:Humans
  21. Kumar V, Stubbs A, Shaw S, Uzuner Ö. Creation of a new longitudinal corpus of clinical narratives. J Biomed Inform. 2015 Dec; 58 Suppl:S6-S10. PMID: 26433122.
    Citations: 11     Fields:    Translation:Humans
  22. Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T. Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS One. 2015; 10(8):e0136651. PMID: 26301417.
    Citations: 43     Fields:    Translation:Humans
  23. Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ. The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells. Elife. 2015 May 22; 4. PMID: 25998054; PMCID: PMC4441007.
    Citations: 17     Fields:    Translation:AnimalsCells
  24. Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015 Sep; 22(5):993-1000. PMID: 25929596.
    Citations: 75     Fields:    Translation:Humans
  25. Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I. Development of phenotype algorithms using electronic medical records and incorporating natural language processing. BMJ. 2015 Apr 24; 350:h1885. PMID: 25911572; PMCID: PMC4707569.
    Citations: 106     Fields:    Translation:Humans
  26. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases. Aliment Pharmacol Ther. 2015 Jun; 41(11):1141-8. PMID: 25864945; PMCID: PMC4420684.
    Citations: 12     Fields:    Translation:Humans
  27. Brettman AD, Tan PH, Tran K, Shaw SY. Applying the logic of genetic interaction to discover small molecules that functionally interact with human disease alleles. Methods Mol Biol. 2015; 1263:15-27. PMID: 25618333; PMCID: PMC4357233.
    Citations:    Fields:    Translation:HumansCells
  28. Xu YX, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW. The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. J Lipid Res. 2015 Feb; 56(2):266-76. PMID: 25528754.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  29. Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Dig Dis Sci. 2015 Feb; 60(2):471-7. PMID: 25213079; PMCID: PMC4304947.
    Citations: 5     Fields:    Translation:Humans
  30. Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014 Nov; 133(11):1369-82. PMID: 25062868.
    Citations: 23     Fields:    Translation:Humans
  31. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):322-329.e1. PMID: 25041865.
    Citations: 36     Fields:    Translation:Humans
  32. Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D. High-throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration. Am J Physiol Cell Physiol. 2014 Oct 01; 307(7):C597-605. PMID: 24944200.
    Citations: 10     Fields:    Translation:AnimalsCells
  33. Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014 Nov 07; 35(42):2972-9. PMID: 24742886.
    Citations: 74     Fields:    Translation:HumansCells
  34. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014 May; 39(10):1136-42. PMID: 24641590.
    Citations: 31     Fields:    Translation:HumansCells
  35. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Nov; 12(11):1905-10. PMID: 24632349.
    Citations: 15     Fields:    Translation:Humans
  36. Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014 Sep; 8(9):956-63. PMID: 24559536.
    Citations: 20     Fields:    Translation:Humans
  37. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1342-8.e1. PMID: 24407106.
    Citations: 18     Fields:    Translation:Humans
  38. Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):2046-50. PMID: 23925980.
    Citations: 32     Fields:    Translation:Humans
  39. Liu Y, Shoji-Kawata S, Sumpter RM, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B. Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):20364-71. PMID: 24277826.
    Citations: 253     Fields:    Translation:HumansAnimalsCells
  40. Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL. Modeling disease severity in multiple sclerosis using electronic health records. PLoS One. 2013; 8(11):e78927. PMID: 24244385.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  41. Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ. Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules. ACS Chem Biol. 2013 Dec 20; 8(12):2724-2733. PMID: 24168452.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  42. Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 May; 12(5):821-7. PMID: 24161349.
    Citations: 41     Fields:    Translation:Humans
  43. Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY. Microfluidic on-chip capture-cycloaddition reaction to reversibly immobilize small molecules or multi-component structures for biosensor applications. J Vis Exp. 2013 Sep 23; (79):e50772. PMID: 24084440.
    Citations:    Fields:    Translation:Cells
  44. Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection. Gastroenterology. 2013 Dec; 145(6):1347-57. PMID: 23973919; PMCID: PMC3840157.
    Citations: 120     Fields:    Translation:HumansAnimalsCells
  45. Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP. Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease. Inflamm Bowel Dis. 2013 Aug; 19(9):1921-7. PMID: 23751398.
    Citations: 92     Fields:    Translation:Humans
  46. Ananthakrishnan AN, Cai T, Savova G, Cheng SC, Chen P, Perez RG, Gainer VS, Murphy SN, Szolovits P, Xia Z, Shaw S, Churchill S, Karlson EW, Kohane I, Plenge RM, Liao KP. Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach. Inflamm Bowel Dis. 2013 Jun; 19(7):1411-20. PMID: 23567779.
    Citations: 80     Fields:    Translation:Humans
  47. Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2014 Jun; 73(6):1170-5. PMID: 23716066.
    Citations: 17     Fields:    Translation:Humans
  48. Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS. Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis. 2013 Jul; 229(1):228-33. PMID: 23701996.
    Citations: 6     Fields:    Translation:HumansCells
  49. Liu R, Rallo R, Weissleder R, Tassa C, Shaw S, Cohen Y. Nano-SAR development for bioactivity of nanoparticles with considerations of decision boundaries. Small. 2013 May 27; 9(9-10):1842-52. PMID: 23423856.
    Citations: 12     Fields:    
  50. Ananthakrishnan AN, Gainer VS, Cai T, Perez RG, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Am J Gastroenterol. 2013 Apr; 108(4):594-601. PMID: 23337479.
    Citations: 29     Fields:    Translation:Humans
  51. Ananthakrishnan AN, Gainer VS, Perez RG, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Perlis RH, Plenge RM, Murphy SN, Liao KP. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Aliment Pharmacol Ther. 2013 Feb; 37(4):445-54. PMID: 23289600.
    Citations: 45     Fields:    Translation:Humans
  52. Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ. Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors. Blood. 2013 Feb 21; 121(8):e50-6. PMID: 23287867; PMCID: PMC3578962.
    Citations: 35     Fields:    Translation:HumansCells
  53. Epa VC, Burden FR, Tassa C, Weissleder R, Shaw S, Winkler DA. Modeling biological activities of nanoparticles. Nano Lett. 2012 Nov 14; 12(11):5808-12. PMID: 23039907.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  54. Chong NW, Koekemoer AL, Ounzain S, Samani NJ, Shin JT, Shaw SY. STARS is essential to maintain cardiac development and function in vivo via a SRF pathway. PLoS One. 2012; 7(7):e40966. PMID: 22815879.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  55. Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY. On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab Chip. 2012 Sep 07; 12(17):3103-10. PMID: 22760641.
    Citations: 9     Fields:    Translation:Cells
  56. Shaw SY, Brettman AD. Phenotyping patient-derived cells for translational studies in cardiovascular disease. Circulation. 2011 Nov 29; 124(22):2444-55. PMID: 22125190; PMCID: PMC3263367.
    Citations: 3     Fields:    Translation:HumansCells
  57. Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R. Supramolecular host-guest interaction for labeling and detection of cellular biomarkers. Angew Chem Int Ed Engl. 2012 Jan 09; 51(2):450-4. PMID: 22113923.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  58. Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM. Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. 2012 Jan; 220(1):145-50. PMID: 22093724.
    Citations: 4     Fields:    Translation:HumansCells
  59. Liong M, Tassa C, Shaw SY, Lee H, Weissleder R. Multiplexed magnetic labeling amplification using oligonucleotide hybridization. Adv Mater. 2011 Sep 22; 23(36):H254-7. PMID: 21780311.
    Citations: 11     Fields:    Translation:HumansCells
  60. Chen HH, Feng Y, Zhang M, Chao W, Josephson L, Shaw SY, Sosnovik DE. Protective effect of the apoptosis-sensing nanoparticle AnxCLIO-Cy5.5. Nanomedicine. 2012 Apr; 8(3):291-8. PMID: 21704591.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  61. Tassa C, Shaw SY, Weissleder R. Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc Chem Res. 2011 Oct 18; 44(10):842-52. PMID: 21661727.
    Citations: 144     Fields:    Translation:HumansAnimals
  62. Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ. Genetic and clinical correlates of early-outgrowth colony-forming units. Circ Cardiovasc Genet. 2011 Jun; 4(3):296-304. PMID: 21493818.
    Citations: 10     Fields:    Translation:HumansCells
  63. Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, MacDonald ME, Seong IS. Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis. Hum Mol Genet. 2011 Jun 15; 20(12):2344-55. PMID: 21447599.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  64. Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL. Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):492-7. PMID: 21183721.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  65. Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A. Quantitative nanostructure-activity relationship modeling. ACS Nano. 2010 Oct 26; 4(10):5703-12. PMID: 20857979.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  66. Cheng S, Cohen KS, Shaw SY, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ. Association of colony-forming units with coronary artery and abdominal aortic calcification. Circulation. 2010 Sep 21; 122(12):1176-82. PMID: 20823386; PMCID: PMC3050056.
    Citations: 5     Fields:    Translation:HumansCells
  67. Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY. Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles. Bioconjug Chem. 2010 Jan; 21(1):14-9. PMID: 20028085.
    Citations: 71     Fields:    Translation:Cells
  68. Shaw SY. Molecular imaging in cardiovascular disease: targets and opportunities. Nat Rev Cardiol. 2009 Sep; 6(9):569-79. PMID: 19621013.
    Citations: 15     Fields:    Translation:HumansAnimals
  69. Kelly KA, Shaw SY, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R. Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries. Integr Biol (Camb). 2009 Apr; 1(4):311-7. PMID: 20023731.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  70. Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D. Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet. 2008 Nov; 4(11):e1000287. PMID: 19043577.
    Citations: 142     Fields:    Translation:HumansCells
  71. Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R. Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7387-92. PMID: 18492802.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  72. Shaw SY. Chemical biology approaches to molecular imaging. Molecular imaging: Principles and practice (R Weissleder, S Gambhir, BD Ross, A Rehemtulla, eds.). 2008.
  73. Lix LM, Yogendran MS, Shaw SY, Burchill C, Metge C, Bond R. Population-based data sources for chronic disease surveillance. Chronic Dis Can. 2008; 29(1):31-8. PMID: 19036221.
    Citations: 48     Fields:    Translation:Humans
  74. Samani NJ, Mahadeva H, Chong N, Shaw SY. Knockdown in zebrafish supports an important role for myocyte stress (ms1) in cardiac development and function. European Heart Journal. 2006; 27(1):473.
  75. Shaw SY, Westly EC, Subramanian A, Clemons PA, Schreiber SL. Chemical profiling of human cells to reveal functional consequences of human disease mutations. Abstracts of papers presented at the 2006 meeting on The Biology of Genomes. 2006; 284.
  76. Low AF, O'Donnell CJ, Kathiresan S, Everett B, Chae CU, Shaw SY, Ellinor PT, MacRae CA. Aging syndrome genes and premature coronary artery disease. BMC Med Genet. 2005 Oct 31; 6:38. PMID: 16262891; PMCID: PMC1289285.
    Citations: 11     Fields:    Translation:Humans
  77. Peterson RT, Shaw SY, Peterson TA, Milan DJ, Zhong TP, Schreiber SL, MacRae CA, Fishman MC. Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol. 2004 May; 22(5):595-9. PMID: 15097998.
    Citations: 138     Fields:    Translation:AnimalsCells
  78. Lee WS, Jain MK, Arkonac BM, Zhang D, Shaw SY, Kashiki S, Maemura K, Lee SL, Hollenberg NK, Lee ME, Haber E. Thy-1, a novel marker for angiogenesis upregulated by inflammatory cytokines. Circ Res. 1998 May 04; 82(8):845-51. PMID: 9576104.
    Citations: 22     Fields:    Translation:AnimalsCells
  79. Shaw SY, Wang JC. Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments. Proc Natl Acad Sci U S A. 1997 Mar 04; 94(5):1692-7. PMID: 9050840; PMCID: PMC19978.
    Citations: 10     Fields:    Translation:AnimalsCells
  80. Runge MS, Harker LA, Bode C, Ruef J, Kelly AB, Marzec UM, Allen E, Caban R, Shaw SY, Haber E, Hanson SR. Enhanced thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons. Circulation. 1996 Sep 15; 94(6):1412-22. PMID: 8823001.
    Citations: 14     Fields:    Translation:Animals
  81. Schildbach JF, Shaw SY, Bruccoleri RE, Haber E, Herzenberg LA, Jager GC, Jeffrey PD, Panka DJ, Parks DR, Near RI, et al. Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody. Protein Sci. 1994 May; 3(5):737-49. PMID: 8061604; PMCID: PMC2142714.
    Citations: 2     Fields:    Translation:AnimalsCells
  82. Shaw SY, Wang JC. DNA knot formation in aqueous solutions. Journal of Knot Theory and its Ramifications. 1994; 3:287-294.
  83. Shaw SY, Wang JC. DNA knot formation in aqueous solutions. Random Knotting and Linking. 1994; 55-66.
  84. Ping J, Schildbach JF, Shaw SY, Quertermous T, Novotny J, Bruccoleri R, Margolies MN. Effect of heavy chain signal peptide mutations and NH2-terminal chain length on binding of anti-digoxin antibodies. J Biol Chem. 1993 Nov 05; 268(31):23000-7. PMID: 8226814.
    Citations: 4     Fields:    Translation:AnimalsCells
  85. Shaw SY, Wang JC. Knotting of a DNA chain during ring closure. Science. 1993 Apr 23; 260(5107):533-6. PMID: 8475384.
    Citations: 69     Fields:    Translation:Cells
  86. Shaw SY, Margolies MN. A spontaneous variant of an antidigoxin hybridoma antibody with increased affinity arises from a heavy chain signal peptide mutation. Mol Immunol. 1992 Apr; 29(4):525-9. PMID: 1565100.
    Citations: 1     Fields:    Translation:AnimalsCells
  87. Runge MS, Quertermous T, Zavodny PJ, Love TW, Bode C, Freitag M, Shaw SY, Huang PL, Chou CC, Mullins D, et al. A recombinant chimeric plasminogen activator with high affinity for fibrin has increased thrombolytic potency in vitro and in vivo. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):10337-41. PMID: 1946453; PMCID: PMC52923.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.