Harvard Catalyst Profiles

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Deborah Jean Culley, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM132668 (CULLEY, DEBORAH J) Aug 1, 2019 - Jul 31, 2024
    NIH/NIGMS
    Cognition and the immunology of postoperative outcomes
    Role: Principal Investigator
  2. R56AG055833 (CULLEY, DEBORAH J) Sep 30, 2018 - Aug 31, 2019
    NIH/NIA
    Preoperative cognitive impairment and adverse geriatric surgical outcomes: role of dysfunctional immunity
    Role: Principal Investigator
  3. R21AG048522 (CULLEY, DEBORAH J) Aug 1, 2015 - Apr 30, 2017
    NIH/NIA
    Preoperative Cognitive Screening in Elderly Surgical Patients: Feasibility and Utility for Predicting Morbidity
    Role: Principal Investigator
  4. K08GM077057 (CULLEY, DEBORAH J) Apr 1, 2006 - Mar 31, 2011
    NIH/NIGMS
    Cellular Mechanisms of General Anesthetic Mediated Neurotoxicity
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hughes CG, Boncyk CS, Culley DJ, Fleisher LA, Leung JM, McDonagh DL, Gan TJ, McEvoy MD, Miller TE. American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention. Anesth Analg. 2020 06; 130(6):1572-1590. PMID: 32022748.
    Citations:    
  2. Sun H, Warner DO, Macario A, Zhou Y, Culley DJ, Keegan MT. Anesthesiologist Burnout, Distress, and Depression: Reply. Anesthesiology. 2020 Jun; 132(6):1601-1602. PMID: 32205550.
    Citations:    
  3. Vutskits L, Culley DJ. GAS, PANDA, and MASK: Reply. Anesthesiology. 2020 Jun; 132(6):1589-1590. PMID: 32224724.
    Citations:    
  4. Kazarian ER, Lopez WY, Eizember S, Blucher JA, Culley DJ, Javedan H, Kang JD, Schoenfeld AJ. Incidental Durotomy is Associated with Increased Risk of Delirium in Patients Aged 65 and Older. Spine (Phila Pa 1976). 2020 Mar 19. PMID: 32205689.
    Citations:    
  5. Liufu N, Liu L, Shen S, Jiang Z, Dong Y, Wang Y, Culley D, Crosby G, Cao M, Shen Y, Marcantonio E, Xie Z, Zhang Y. Anesthesia and surgery induce age-dependent changes in behaviors and microbiota. Aging (Albany NY). 2020 01 24; 12(2):1965-1986. PMID: 31974315.
    Citations:    
  6. Eckenhoff RG, Maze M, Xie Z, Culley DJ, Goodlin SJ, Zuo Z, Wei H, Whittington RA, Terrando N, Orser BA, Eckenhoff MF. Perioperative Neurocognitive Disorder: State of the Preclinical Science. Anesthesiology. 2020 01; 132(1):55-68. PMID: 31834869.
    Citations:    
  7. Mahanna-Gabrielli E, Schenning KJ, Eriksson LI, Browndyke JN, Wright CB, Culley DJ, Evered L, Scott DA, Wang NY, Brown CH, Oh E, Purdon P, Inouye S, Berger M, Whittington RA, Price CC, Deiner S. Corrigendum to 'State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018' (Br J Anaesth 2019; 123: 464-478). Br J Anaesth. 2019 12; 123(6):917. PMID: 31591017.
    Citations:    
  8. Susano MJ, Crosby G, Culley DJ. Reply to "Postoperative Delirium and EEG Monitoring". J Neurosurg Anesthesiol. 2019 10; 31(4):447-448. PMID: 31479070.
    Citations:    
  9. Vutskits L, Culley DJ. GAS, PANDA, and MASK: No Evidence of Clinical Anesthetic Neurotoxicity! Anesthesiology. 2019 10; 131(4):762-764. PMID: 31246606.
    Citations:    
  10. Susano MJ, Scheetz SD, Grasfield RH, Cheung D, Xu X, Kang JD, Smith TR, Lu Y, Groff MW, Chi JH, Crosby G, Culley DJ. Retrospective Analysis of Perioperative Variables Associated With Postoperative Delirium and Other Adverse Outcomes in Older Patients After Spine Surgery. J Neurosurg Anesthesiol. 2019 Oct; 31(4):385-391. PMID: 30531557.
    Citations:    Fields:    
  11. Sun H, Warner DO, Macario A, Zhou Y, Culley DJ, Keegan MT. Repeated Cross-sectional Surveys of Burnout, Distress, and Depression among Anesthesiology Residents and First-year Graduates. Anesthesiology. 2019 09; 131(3):668-677. PMID: 31166235.
    Citations:    
  12. Berger M, Angst MS, Culley DJ, Price CE, Scott DA, Whittington RA, Eckenhoff RG. In Response. Anesth Analg. 2019 09; 129(3):e112-e113. PMID: 31425253.
    Citations:    
  13. Mahanna-Gabrielli E, Schenning KJ, Eriksson LI, Browndyke JN, Wright CB, Culley DJ, Evered L, Scott DA, Wang NY, Brown CH, Oh E, Purdon P, Inouye S, Berger M, Whittington RA, Price CC, Deiner S. State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018. Br J Anaesth. 2019 10; 123(4):464-478. PMID: 31439308.
    Citations:    
  14. Susano MJ, Crosby G, Culley DJ. Response to Letter to the Editor From Lobo et al. J Neurosurg Anesthesiol. 2019 Jul 02. PMID: 31274671.
    Citations:    
  15. Berger M, Angst MS, Culley DJ, Price CE, Scott DA, Whittington RA, Eckenhoff RG. In Response. Anesth Analg. 2019 Jul 02. PMID: 31283620.
    Citations:    
  16. Cole DJ, Culley DJ, Fahy BG, Warner DO. Maintenance of Certification: Comment. Anesthesiology. 2019 06; 130(6):1091-1092. PMID: 31090622.
    Citations:    
  17. Sherman JB, Chatterjee A, Urman RD, Culley DJ, Crosby GJ, Cooper Z, Javedan H, Hepner DL, Bader AM. Implementation of Routine Cognitive Screening in the Preoperative Assessment Clinic. A A Pract. 2019 Feb 15; 12(4):125-127. PMID: 30234511.
    Citations:    
  18. Friese MB, Nathan M, Culley DJ, Crosby G. Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice. PLoS One. 2018; 13(12):e0209283. PMID: 30571762.
    Citations:    Fields:    
  19. Berger M, Schenning KJ, Brown CH, Deiner SG, Whittington RA, Eckenhoff RG, Angst MS, Avramescu S, Bekker A, Brzezinski M, Crosby G, Culley DJ, Eckenhoff M, Eriksson LI, Evered L, Ibinson J, Kline RP, Kofke A, Ma D, Mathew JP, Maze M, Orser BA, Price CC, Scott DA, Silbert B, Su D, Terrando N, Wang DS, Wei H, Xie Z, Zuo Z. Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group. Anesth Analg. 2018 12; 127(6):1406-1413. PMID: 30303868.
    Citations:    Fields:    
  20. Fahy BG, Culley DJ, Sun H, Dainer R, Lutkoski BP, Lien CA. Gender Distribution of the American Board of Anesthesiology Diplomates, Examiners, and Directors (1985-2015). Anesth Analg. 2018 08; 127(2):564-568. PMID: 29683833.
    Citations:    Fields:    
  21. Culley DJ, Avram MJ. Young Brain and Anesthesia: Refusal of Anesthesia Is Not an Option! Anesthesiology. 2018 04; 128(4):697-699. PMID: 29533966.
    Citations:    Fields:    
  22. Blum RH, Muret-Wagstaff SL, Boulet JR, Cooper JB, Petrusa ER, Baker KH, Davidyuk G, Dearden JL, Feinstein DM, Jones SB, Kimball WR, Mitchell JD, Nadelberg RL, Wiser SH, Albrecht MA, Anastasi AK, Bose RR, Chang LY, Culley DJ, Fisher LJ, Grover M, Klainer SB, Kveraga R, Martel JP, McKenna SS, Minehart RD, Mitchell JD, Mountjoy JR, Pawlowski JB, Pilon RN, Shook DC, Silver DA, Warfield CA, Zaleski KL. Simulation-based Assessment to Reliably Identify Key Resident Performance Attributes. Anesthesiology. 2018 04; 128(4):821-831. PMID: 29369062.
    Citations: 1     Fields:    
  23. Palanisamy A, Kannappan R, Xu Z, Martino A, Friese MB, Boyd JD, Crosby G, Culley DJ. Oxytocin alters cell fate selection of rat neural progenitor cells in vitro. PLoS One. 2018; 13(1):e0191160. PMID: 29346405.
    Citations:    Fields:    Translation:HumansAnimalsCells
  24. Palanisamy A, Crosby G, Culley DJ. EARLY gestational exposure to isoflurane causes persistent cell loss in the dentate gyrus of adult male rats. Behav Brain Funct. 2017 Dec 26; 13(1):14. PMID: 29279051.
    Citations:    Fields:    Translation:AnimalsCells
  25. Culley DJ, Flaherty D, Fahey MC, Rudolph JL, Javedan H, Huang CC, Wright J, Bader AM, Hyman BT, Blacker D, Crosby G. Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients. Anesthesiology. 2017 11; 127(5):765-774. PMID: 28891828.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  26. Miao H, Dong Y, Zhang Y, Zheng H, Shen Y, Crosby G, Culley DJ, Marcantonio ER, Xie Z. Anesthetic Isoflurane or Desflurane Plus Surgery Differently Affects Cognitive Function in Alzheimer's Disease Transgenic Mice. Mol Neurobiol. 2018 Jul; 55(7):5623-5638. PMID: 28986748.
    Citations:    Fields:    
  27. Zhou Y, Sun H, Culley DJ, Young A, Harman AE, Warner DO. Effectiveness of Written and Oral Specialty Certification Examinations to Predict Actions against the Medical Licenses of Anesthesiologists. Anesthesiology. 2017 06; 126(6):1171-1179. PMID: 28383325.
    Citations:    Fields:    Translation:Humans
  28. Fahy BG, Vasilopoulos T, White P, Culley DJ. Academic Productivity of Accreditation Council for Graduate Medical Education-Accredited Critical Care Fellowship Program Directors. Crit Care Med. 2016 Dec; 44(12):e1194-e1201. PMID: 27495817.
    Citations:    Fields:    Translation:Humans
  29. Sun H, Zhou Y, Culley DJ, Lien CA, Harman AE, Warner DO. Association between Participation in an Intensive Longitudinal Assessment Program and Performance on a Cognitive Examination in the Maintenance of Certification in Anesthesiology Program®. Anesthesiology. 2016 11; 125(5):1046-1055. PMID: 27560464.
    Citations:    Fields:    Translation:Humans
  30. Palanisamy A, Friese MB, Cotran E, Moller L, Boyd JD, Crosby G, Culley DJ. Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro. PLoS One. 2016; 11(7):e0158058. PMID: 27379684.
    Citations: 4     Fields:    Translation:AnimalsCells
  31. Culley DJ, Flaherty D, Reddy S, Fahey MC, Rudolph J, Huang CC, Liu X, Xie Z, Bader AM, Hyman BT, Blacker D, Crosby G. Preoperative Cognitive Stratification of Older Elective Surgical Patients: A Cross-Sectional Study. Anesth Analg. 2016 07; 123(1):186-92. PMID: 27028776.
    Citations: 4     Fields:    Translation:Humans
  32. Culley DJ, Crosby G. Dementia after Cardiac Surgery: Is It the Procedure or the Patient? Anesthesiology. 2016 07; 125(1):14-6. PMID: 27127918.
    Citations: 1     Fields:    Translation:Humans
  33. Englert JA, Macias AA, Amador-Munoz D, Pinilla Vera M, Isabelle C, Guan J, Magaoay B, Suarez Velandia M, Coronata A, Lee A, Fredenburgh LE, Culley DJ, Crosby G, Baron RM. Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity. Anesthesiology. 2015 Aug; 123(2):377-88. PMID: 26068207.
    Citations: 10     Fields:    Translation:AnimalsCells
  34. Culley DJ, Crosby G. Prehabilitation for Prevention of Postoperative Cognitive Dysfunction? Anesthesiology. 2015 Jul; 123(1):7-9. PMID: 26001030.
    Citations: 1     Fields:    Translation:Animals
  35. Warner DO, Sun H, Harman AE, Culley DJ. Feasibility of patient and peer surveys for Maintenance of Certification among diplomates of the American Board of Anesthesiology. J Clin Anesth. 2015 Jun; 27(4):290-5. PMID: 25792177.
    Citations:    Fields:    Translation:Humans
  36. Sun H, Culley DJ, Lien CA, Kitchener DL, Harman AE, Warner DO. Predictors of performance on the Maintenance of Certification in Anesthesiology Program® (MOCA®) examination. J Clin Anesth. 2015 Feb; 27(1):1-6. PMID: 25468588.
    Citations:    Fields:    Translation:Humans
  37. Tao G, Zhang J, Zhang L, Dong Y, Yu B, Crosby G, Culley DJ, Zhang Y, Xie Z. Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3ß activation in young mice. Anesthesiology. 2014 Sep; 121(3):510-27. PMID: 24787352.
    Citations: 17     Fields:    Translation:AnimalsCells
  38. Culley DJ, Snayd M, Baxter MG, Xie Z, Lee IH, Rudolph J, Inouye SK, Marcantonio ER, Crosby G. Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium. Front Aging Neurosci. 2014; 6:107. PMID: 24959140.
    Citations: 13     
  39. Xu Z, Dong Y, Wang H, Culley DJ, Marcantonio ER, Crosby G, Tanzi RE, Zhang Y, Xie Z. Peripheral surgical wounding and age-dependent neuroinflammation in mice. PLoS One. 2014; 9(5):e96752. PMID: 24796537.
    Citations: 14     Fields:    Translation:Animals
  40. Crosby G, Culley DJ, Dexter F. Cognitive outcome of surgery: is there no place like home? Anesth Analg. 2014 May; 118(5):898-900. PMID: 24781557.
    Citations: 2     Fields:    Translation:Humans
  41. Schartel SA, Kuhn C, Culley DJ, Wood M, Cohen N. Development of the anesthesiology educational milestones. J Grad Med Educ. 2014 Mar; 6(1 Suppl 1):12-4. PMID: 24701261.
    Citations: 5     Fields:    
  42. Zhang Y, Pan C, Wu X, Dong Y, Culley DJ, Crosby G, Li T, Xie Z. Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochrome c levels between mice neural progenitor cells and neurons. Front Cell Neurosci. 2014; 8:14. PMID: 24523673.
    Citations: 3     
  43. Xu Z, Dong Y, Wang H, Culley DJ, Marcantonio ER, Crosby G, Tanzi RE, Zhang Y, Xie Z. Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice. Sci Rep. 2014 Jan 20; 4:3766. PMID: 24441878.
    Citations: 26     Fields:    Translation:HumansAnimals
  44. Culley DJ, Fahy BG, Xie Z, Lekowski R, Buetler S, Liu X, Cohen NH, Crosby G. Academic productivity of directors of ACGME-accredited residency programs in surgery and anesthesiology. Anesth Analg. 2014 Jan; 118(1):200-5. PMID: 24247229.
    Citations:    Fields:    Translation:Humans
  45. Culley DJ, Cotran EK, Karlsson E, Palanisamy A, Boyd JD, Xie Z, Crosby G. Isoflurane affects the cytoskeleton but not survival, proliferation, or synaptogenic properties of rat astrocytes in vitro. Br J Anaesth. 2013 Jun; 110 Suppl 1:i19-28. PMID: 23722058.
    Citations: 13     Fields:    Translation:AnimalsCells
  46. Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W, Soriano SG, Stratmann G, Vutskits L, Xie Z, Hemmings HC. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. Br J Anaesth. 2013 Aug; 111(2):143-51. PMID: 23722106.
    Citations: 50     Fields:    Translation:HumansAnimals
  47. Culley DJ. Report on SNACC's 40th anniversary meeting. J Neurosurg Anesthesiol. 2013 Apr; 25(2):221-2. PMID: 23456035.
    Citations:    Fields:    
  48. Zheng H, Dong Y, Xu Z, Crosby G, Culley DJ, Zhang Y, Xie Z. Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice. Anesthesiology. 2013 Mar; 118(3):516-26. PMID: 23314109.
    Citations: 40     Fields:    Translation:Animals
  49. Culley DJ, Sun H, Harman AE, Warner DO. Perceived value of Board certification and the Maintenance of Certification in Anesthesiology Program (MOCA®). J Clin Anesth. 2013 Feb; 25(1):12-9. PMID: 23391341.
    Citations: 4     Fields:    Translation:Humans
  50. Crosby G, Culley DJ. Anesthesia & analgesia by the numbers: then & now. Anesth Analg. 2012 Dec; 115(6):1265-7. PMID: 23175575.
    Citations:    Fields:    Translation:Humans
  51. Zhang Y, Xu Z, Wang H, Dong Y, Shi HN, Culley DJ, Crosby G, Marcantonio ER, Tanzi RE, Xie Z. Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol. 2012 May; 71(5):687-98. PMID: 22368036.
    Citations: 84     Fields:    Translation:HumansAnimalsCells
  52. Crosby G, Culley DJ. Processed electroencephalogram and depth of anesthesia: window to nowhere or into the brain? Anesthesiology. 2012 Feb; 116(2):235-7. PMID: 22222481.
    Citations: 3     Fields:    Translation:Humans
  53. Culley DJ, Maze M, Crosby G. Reprogramming of the infant brain by surgery with general anesthesia. Mayo Clin Proc. 2012 Feb; 87(2):110-3. PMID: 22305023.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  54. Palanisamy A, Crosby G, Culley DJ. In reply. Anesthesiology. 2011 Oct; 115(4):904-5. PMID: 21934420.
    Citations:    
  55. Culley DJ, Boyd JD, Palanisamy A, Xie Z, Kojima K, Vacanti CA, Tanzi RE, Crosby G. Isoflurane decreases self-renewal capacity of rat cultured neural stem cells. Anesthesiology. 2011 Oct; 115(4):754-63. PMID: 21666433.
    Citations: 24     Fields:    Translation:AnimalsCells
  56. Crosby G, Culley DJ, Hyman BT. Preoperative cognitive assessment of the elderly surgical patient: a call for action. Anesthesiology. 2011 Jun; 114(6):1265-8. PMID: 21490501.
    Citations: 9     Fields:    Translation:Humans
  57. Crosby G, Culley DJ. Surgery and anesthesia: healing the body but harming the brain? Anesth Analg. 2011 May; 112(5):999-1001. PMID: 21515644.
    Citations: 3     Fields:    Translation:Humans
  58. Palanisamy A, Baxter MG, Keel PK, Xie Z, Crosby G, Culley DJ. Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology. 2011 Mar; 114(3):521-8. PMID: 21307768.
    Citations: 27     Fields:    Translation:Animals
  59. Wu X, Lu Y, Dong Y, Zhang G, Zhang Y, Xu Z, Culley DJ, Crosby G, Marcantonio ER, Tanzi RE, Xie Z. The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-a, IL-6, and IL-1ß. Neurobiol Aging. 2012 Jul; 33(7):1364-78. PMID: 21190757.
    Citations: 69     Fields:    Translation:AnimalsCells
  60. Rudolph JL, Schreiber KA, Culley DJ, McGlinchey RE, Crosby G, Levitsky S, Marcantonio ER. Measurement of post-operative cognitive dysfunction after cardiac surgery: a systematic review. Acta Anaesthesiol Scand. 2010 Jul; 54(6):663-77. PMID: 20397979.
    Citations: 34     Fields:    Translation:Humans
  61. Crosby G, Culley DJ, Patel PM. At the sharp end of spines: anesthetic effects on synaptic remodeling in the developing brain. Anesthesiology. 2010 Mar; 112(3):521-3. PMID: 20124984.
    Citations: 2     Fields:    Translation:HumansCells
  62. Crosby G, Culley DJ, Marcantonio ER. Delirium: a cognitive cost of the comfort of procedural sedation in elderly patients? Mayo Clin Proc. 2010 Jan; 85(1):12-4. PMID: 20042555.
    Citations: 1     Fields:    Translation:Humans
  63. Dong Y, Zhang G, Zhang B, Moir RD, Xia W, Marcantonio ER, Culley DJ, Crosby G, Tanzi RE, Xie Z. The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol. 2009 May; 66(5):620-31. PMID: 19433662.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  64. Baranov D, Bickler PE, Crosby GJ, Culley DJ, Eckenhoff MF, Eckenhoff RG, Hogan KJ, Jevtovic-Todorovic V, Palotás A, Perouansky M, Planel E, Silverstein JH, Wei H, Whittington RA, Xie Z, Zuo Z. Consensus statement: First International Workshop on Anesthetics and Alzheimer's disease. Anesth Analg. 2009 May; 108(5):1627-30. PMID: 19372347.
    Citations: 39     Fields:    Translation:HumansAnimals
  65. Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, Moir RD, Frosch MP, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol. 2008 Dec; 64(6):618-27. PMID: 19006075.
    Citations: 103     Fields:    Translation:AnimalsCells
  66. Lee IH, Culley DJ, Baxter MG, Xie Z, Tanzi RE, Crosby G. Spatial memory is intact in aged rats after propofol anesthesia. Anesth Analg. 2008 Oct; 107(4):1211-5. PMID: 18806029.
    Citations: 10     Fields:    Translation:Animals
  67. Marcantonio ER, Aneja J, Jones RN, Alsop DC, Fong TG, Crosby GJ, Culley DJ, Cupples LA, Inouye SK. Maximizing clinical research participation in vulnerable older persons: identification of barriers and motivators. J Am Geriatr Soc. 2008 Aug; 56(8):1522-7. PMID: 18662204.
    Citations: 16     Fields:    Translation:Humans
  68. Rudolph JL, Marcantonio ER, Culley DJ, Silverstein JH, Rasmussen LS, Crosby GJ, Inouye SK. Delirium is associated with early postoperative cognitive dysfunction. Anaesthesia. 2008 Sep; 63(9):941-7. PMID: 18547292.
    Citations: 25     Fields:    Translation:Humans
  69. Zhang G, Dong Y, Zhang B, Ichinose F, Wu X, Culley DJ, Crosby G, Tanzi RE, Xie Z. Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci. 2008 Apr 23; 28(17):4551-60. PMID: 18434534.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  70. Culley DJ, Crosby G. Nitrous oxide in neuroanesthesia: tried and true or toxin? Anesthesiology. 2008 Apr; 108(4):553-4. PMID: 18362583.
    Citations:    Fields:    Translation:Humans
  71. Zhang B, Dong Y, Zhang G, Moir RD, Xia W, Yue Y, Tian M, Culley DJ, Crosby G, Tanzi RE, Xie Z. The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem. 2008 May 02; 283(18):11866-75. PMID: 18326038.
    Citations: 35     Fields:    Translation:HumansCells
  72. Baxter MG, Murphy KL, Crosby G, Culley DJ. Different behavioral effects of neurotoxic dorsal hippocampal lesions placed under either isoflurane or propofol anesthesia. Hippocampus. 2008; 18(3):245-50. PMID: 18058823.
    Citations: 1     Fields:    Translation:Animals
  73. Culley DJ, Xie Z, Crosby G. General anesthetic-induced neurotoxicity: an emerging problem for the young and old? Curr Opin Anaesthesiol. 2007 Oct; 20(5):408-13. PMID: 17873593.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  74. Culley DJ, Raghavan SV, Waly M, Baxter MG, Yukhananov R, Deth RC, Crosby G. Nitrous oxide decreases cortical methionine synthase transiently but produces lasting memory impairment in aged rats. Anesth Analg. 2007 Jul; 105(1):83-8. PMID: 17578961.
    Citations: 9     Fields:    Translation:Animals
  75. Culley DJ, Crosby G, Xie Z, Vacanti CA, Kitz RJ, Zapol WM. Career National Institutes of Health funding and scholarship of chairpersons of academic departments of anesthesiology and surgery. Anesthesiology. 2007 Apr; 106(4):836-42. PMID: 17413922.
    Citations: 2     Fields:    Translation:Humans
  76. Xie Z, Dong Y, Maeda U, Moir RD, Xia W, Culley DJ, Crosby G, Tanzi RE. The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation. J Neurosci. 2007 Feb 07; 27(6):1247-54. PMID: 17287498.
    Citations: 86     Fields:    Translation:HumansCells
  77. Marcantonio ER, Rudolph JL, Culley D, Crosby G, Alsop D, Inouye SK. Serum biomarkers for delirium. J Gerontol A Biol Sci Med Sci. 2006 Dec; 61(12):1281-6. PMID: 17234821.
    Citations: 28     Fields:    Translation:Humans
  78. Xie Z, Dong Y, Maeda U, Moir R, Inouye SK, Culley DJ, Crosby G, Tanzi RE. Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci. 2006 Dec; 61(12):1300-6. PMID: 17234824.
    Citations: 48     Fields:    Translation:HumansCells
  79. Culley DJ, Yukhananov RY, Xie Z, Gali RR, Tanzi RE, Crosby G. Altered hippocampal gene expression 2 days after general anesthesia in rats. Eur J Pharmacol. 2006 Nov 07; 549(1-3):71-8. PMID: 16979155.
    Citations: 12     Fields:    Translation:Animals
  80. Xie Z, Dong Y, Maeda U, Alfille P, Culley DJ, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology. 2006 May; 104(5):988-94. PMID: 16645451.
    Citations: 85     Fields:    Translation:HumansCells
  81. Culley DJ, Loguinov A, Yukhananov R, Crosby G. General anesthesia does not reduce life expectancy in aged rats. Anesth Analg. 2006 Mar; 102(3):956-9. PMID: 16492858.
    Citations: 2     Fields:    Translation:Animals
  82. Crosby C, Culley DJ, Baxter MG, Yukhananov R, Crosby G. Spatial memory performance 2 weeks after general anesthesia in adult rats. Anesth Analg. 2005 Nov; 101(5):1389-92. PMID: 16243999.
    Citations: 19     Fields:    Translation:Animals
  83. Culley DJ, Baxter MG, Crosby CA, Yukhananov R, Crosby G. Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats. Anesth Analg. 2004 Nov; 99(5):1393-7; table of contents. PMID: 15502036.
    Citations: 47     Fields:    Translation:Animals
  84. Tran T, Culley DJ, Crosby G. Hemorrhagic stroke after spinal anesthesia and minor surgery. J Clin Anesth. 2004 Jun; 16(4):293-5. PMID: 15261323.
    Citations:    Fields:    Translation:Humans
  85. Culley DJ, Baxter MG, Yukhananov R, Crosby G. Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats. Anesthesiology. 2004 Feb; 100(2):309-14. PMID: 14739805.
    Citations: 95     Fields:    Translation:Animals
  86. Culley DJ, Crosby G. Mechanisms of postoperative neurobehavioral deficits and stroke may differ. Anesth Analg. 2003 Aug; 97(2):601; author reply 601. PMID: 12873962.
    Citations:    Fields:    Translation:Humans
  87. Culley DJ, Baxter M, Yukhananov R, Crosby G. The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg. 2003 Apr; 96(4):1004-9, table of contents. PMID: 12651650.
    Citations: 74     Fields:    Translation:Animals
  88. Walther MM, Johnson B, Culley D, Shah R, Weber J, Venzon D, Yang JC, Linehan WM, Rosenberg SA. Serum interleukin-6 levels in metastatic renal cell carcinoma before treatment with interleukin-2 correlates with paraneoplastic syndromes but not patient survival. J Urol. 1998 Mar; 159(3):718-22. PMID: 9474133.
    Citations: 11     Fields:    Translation:HumansCells
  89. Culley DJ, Berger MS, Shaw D, Geyer R. An analysis of factors determining the need for ventriculoperitoneal shunts after posterior fossa tumor surgery in children. Neurosurgery. 1994 Mar; 34(3):402-7; discussion 407-8. PMID: 8190214.
    Citations: 19     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.