Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Wenyi Wei, Ph.D.

Co-Author

This page shows the publications co-authored by Wenyi Wei and Hiroyuki Inuzuka.
Connection Strength

7.590
  1. Acetylation-dependent regulation of Skp2 function. Cell. 2012 Jul 06; 150(1):179-93.
    View in: PubMed
    Score: 0.540
  2. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. Nature. 2011 Mar 03; 471(7336):104-9.
    View in: PubMed
    Score: 0.492
  3. Mcl-1 ubiquitination and destruction. Oncotarget. 2011 Mar; 2(3):239-44.
    View in: PubMed
    Score: 0.491
  4. Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. Oncotarget. 2010 Nov; 1(7):685-90.
    View in: PubMed
    Score: 0.480
  5. Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. Cancer Cell. 2010 Aug 09; 18(2):147-59.
    View in: PubMed
    Score: 0.473
  6. Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nat Cell Biol. 2019 05; 21(5):662-663.
    View in: PubMed
    Score: 0.216
  7. Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nat Med. 2017 Sep; 23(9):1063-1071.
    View in: PubMed
    Score: 0.192
  8. Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function. Sci Signal. 2017 02 14; 10(466).
    View in: PubMed
    Score: 0.186
  9. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discov. 2017 04; 7(4):424-441.
    View in: PubMed
    Score: 0.185
  10. The SCFß-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. Sci Signal. 2017 01 03; 10(460).
    View in: PubMed
    Score: 0.184
  11. pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science. 2016 08 26; 353(6302):929-32.
    View in: PubMed
    Score: 0.180
  12. SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. Mol Cell. 2015 Sep 17; 59(6):917-30.
    View in: PubMed
    Score: 0.168
  13. SCFß-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination. Oncotarget. 2014 Jun 30; 5(12):4211-21.
    View in: PubMed
    Score: 0.155
  14. APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction. Dev Cell. 2014 May 27; 29(4):377-91.
    View in: PubMed
    Score: 0.154
  15. Roles of F-box proteins in cancer. Nat Rev Cancer. 2014 Apr; 14(4):233-47.
    View in: PubMed
    Score: 0.152
  16. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature. 2014 Apr 24; 508(7497):541-5.
    View in: PubMed
    Score: 0.151
  17. SCF ß-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration. Oncotarget. 2013 Dec; 4(12):2339-53.
    View in: PubMed
    Score: 0.149
  18. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nat Cell Biol. 2013 Nov; 15(11):1340-50.
    View in: PubMed
    Score: 0.148
  19. SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression. Cell Rep. 2013 Aug 29; 4(4):803-16.
    View in: PubMed
    Score: 0.146
  20. Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Res. 2013 Jul; 23(7):947-61.
    View in: PubMed
    Score: 0.143
  21. Cdc20: a potential novel therapeutic target for cancer treatment. Curr Pharm Des. 2013; 19(18):3210-4.
    View in: PubMed
    Score: 0.140
  22. Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2. Oncotarget. 2012 Nov; 3(11):1294-300.
    View in: PubMed
    Score: 0.138
  23. DNA damage-induced activation of ATM promotes ß-TRCP-mediated Mdm2 ubiquitination and destruction. Oncotarget. 2012 Sep; 3(9):1026-35.
    View in: PubMed
    Score: 0.136
  24. SCF(ß-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med. 2012 Jul 02; 209(7):1289-307.
    View in: PubMed
    Score: 0.134
  25. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction. Cell Rep. 2012 May 31; 1(5):434-43.
    View in: PubMed
    Score: 0.134
  26. An evolving role for DEPTOR in tumor development and progression. Neoplasia. 2012 May; 14(5):368-75.
    View in: PubMed
    Score: 0.133
  27. DEPTOR ubiquitination and destruction by SCF(ß-TrCP). Am J Physiol Endocrinol Metab. 2012 Jul 15; 303(2):E163-9.
    View in: PubMed
    Score: 0.132
  28. Tumor suppressor functions of FBW7 in cancer development and progression. FEBS Lett. 2012 May 21; 586(10):1409-18.
    View in: PubMed
    Score: 0.132
  29. Skp2 is a promising therapeutic target in breast cancer. Front Oncol. 2012 Jan 04; 1(57).
    View in: PubMed
    Score: 0.130
  30. Emerging roles of the FBW7 tumour suppressor in stem cell differentiation. . 2011 Dec 23; 13(1):36-43.
    View in: PubMed
    Score: 0.130
  31. Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Mol Cell. 2011 Dec 09; 44(5):721-33.
    View in: PubMed
    Score: 0.130
  32. mTOR drives its own activation via SCF(ßTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell. 2011 Oct 21; 44(2):290-303.
    View in: PubMed
    Score: 0.128
  33. Skp2: a novel potential therapeutic target for prostate cancer. Biochim Biophys Acta. 2012 Jan; 1825(1):11-7.
    View in: PubMed
    Score: 0.128
  34. The two faces of FBW7 in cancer drug resistance. Bioessays. 2011 Nov; 33(11):851-9.
    View in: PubMed
    Score: 0.127
  35. Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Mol Cell. 2010 Sep 10; 39(5):797-808.
    View in: PubMed
    Score: 0.119
  36. Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1. Cell Div. 2009 Jun 23; 4:11.
    View in: PubMed
    Score: 0.109
  37. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Mol Biol Cell. 2009 Jul; 20(14):3305-16.
    View in: PubMed
    Score: 0.109
  38. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Nat Cell Biol. 2009 Apr; 11(4):397-408.
    View in: PubMed
    Score: 0.107
  39. Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis. Methods Enzymol. 2008; 446:205-23.
    View in: PubMed
    Score: 0.099
  40. Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors. Sci Signal. 2018 03 13; 11(521).
    View in: PubMed
    Score: 0.050
  41. G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells. Nat Cell Biol. 2017 03; 19(3):177-188.
    View in: PubMed
    Score: 0.046
  42. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014 Nov 20; 56(4):595-607.
    View in: PubMed
    Score: 0.040
  43. Cyclin C is a haploinsufficient tumour suppressor. Nat Cell Biol. 2014 Nov; 16(11):1080-91.
    View in: PubMed
    Score: 0.040
  44. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase. Mol Cell. 2012 Jun 29; 46(6):771-83.
    View in: PubMed
    Score: 0.033
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.