Harvard Catalyst Profiles

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M. Amin Arnaout, M.D.

Concepts

This page shows the publications M. Arnaout has written about Structure-Activity Relationship.
Connection Strength

0.220
  1. Structure-guided design of pure orthosteric inhibitors of aIIbß3 that prevent thrombosis but preserve hemostasis. Nat Commun. 2020 01 21; 11(1):398.
    View in: PubMed
    Score: 0.133
  2. The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18. Blood. 2007 Apr 15; 109(8):3513-20.
    View in: PubMed
    Score: 0.054
  3. A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding. Cell. 1993 Mar 26; 72(6):857-67.
    View in: PubMed
    Score: 0.021
  4. Two conformations of the integrin A-domain (I-domain): a pathway for activation? Structure. 1995 Dec 15; 3(12):1333-40.
    View in: PubMed
    Score: 0.006
  5. Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18). Cell. 1995 Feb 24; 80(4):631-8.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.