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M. Amin Arnaout, M.D.

Concepts

This page shows the publications M. Arnaout has written about Molecular Sequence Data.
Connection Strength

0.663
  1. Atomic basis for the species-specific inhibition of aV integrins by monoclonal antibody 17E6 is revealed by the crystal structure of aVß3 ectodomain-17E6 Fab complex. J Biol Chem. 2014 May 16; 289(20):13801-9.
    View in: PubMed
    Score: 0.050
  2. Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89. Stem Cells. 2014 Mar; 32(3):791-801.
    View in: PubMed
    Score: 0.050
  3. Crystal structure of the complete integrin alphaVbeta3 ectodomain plus an alpha/beta transmembrane fragment. J Cell Biol. 2009 Aug 24; 186(4):589-600.
    View in: PubMed
    Score: 0.037
  4. Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function. J Immunol. 2008 Feb 01; 180(3):1713-8.
    View in: PubMed
    Score: 0.033
  5. Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol. 2007 Oct; 19(5):495-507.
    View in: PubMed
    Score: 0.032
  6. A novel adaptation of the integrin PSI domain revealed from its crystal structure. J Biol Chem. 2004 Sep 24; 279(39):40252-4.
    View in: PubMed
    Score: 0.026
  7. The zinc finger transcription factor ZBP-89 is a repressor of the human beta 2-integrin CD11b gene. Blood. 2003 Feb 01; 101(3):894-902.
    View in: PubMed
    Score: 0.023
  8. Does the integrin alphaA domain act as a ligand for its betaA domain? Curr Biol. 2002 May 14; 12(10):R340-2.
    View in: PubMed
    Score: 0.022
  9. During differentiation of the monocytic cell line U937, Pur alpha mediates induction of the CD11c beta 2 integrin gene promoter. J Immunol. 2002 Apr 15; 168(8):3887-93.
    View in: PubMed
    Score: 0.022
  10. WAC, a novel WW domain-containing adapter with a coiled-coil region, is colocalized with splicing factor SC35. Genomics. 2002 Jan; 79(1):87-94.
    View in: PubMed
    Score: 0.022
  11. Polycystin-1 interacts with intermediate filaments. J Biol Chem. 2001 Dec 07; 276(49):46544-52.
    View in: PubMed
    Score: 0.021
  12. Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science. 2001 Oct 12; 294(5541):339-45.
    View in: PubMed
    Score: 0.021
  13. An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain. J Biol Chem. 2000 Dec 08; 275(49):38762-7.
    View in: PubMed
    Score: 0.020
  14. Induction of the CD11b gene during activation of the monocytic cell line U937 requires a novel nuclear factor MS-2. J Immunol. 1996 Dec 15; 157(12):5597-605.
    View in: PubMed
    Score: 0.015
  15. Solvent-accessible residues on the metal ion-dependent adhesion site face of integrin CR3 mediate its binding to the neutrophil inhibitory factor. J Biol Chem. 1996 Jul 05; 271(27):15858-61.
    View in: PubMed
    Score: 0.015
  16. Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB J. 2015 Dec; 29(12):4989-5005.
    View in: PubMed
    Score: 0.014
  17. Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18. J Immunol. 1995 Apr 01; 154(7):3461-70.
    View in: PubMed
    Score: 0.014
  18. The A-domain of beta 2 integrin CR3 (CD11b/CD18) is a receptor for the hookworm-derived neutrophil adhesion inhibitor NIF. J Cell Biol. 1994 Dec; 127(6 Pt 2):2081-91.
    View in: PubMed
    Score: 0.013
  19. Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18). Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10680-4.
    View in: PubMed
    Score: 0.013
  20. The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elements. Mol Cell Biol. 1994 Apr; 14(4):2604-15.
    View in: PubMed
    Score: 0.013
  21. Cytoplasmic tails of human complement receptor type 3 (CR3, CD11b/CD18) regulate ligand avidity and the internalization of occupied receptors. J Immunol. 1993 Jul 15; 151(2):990-1002.
    View in: PubMed
    Score: 0.012
  22. Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5. J Immunol. 1993 Jul 15; 151(2):810-3.
    View in: PubMed
    Score: 0.012
  23. Identification of cell-specific and developmentally regulated nuclear factors that direct myeloid and lymphoid expression of the CD11a gene. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5364-8.
    View in: PubMed
    Score: 0.012
  24. A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding. Cell. 1993 Mar 26; 72(6):857-67.
    View in: PubMed
    Score: 0.012
  25. Genetic cause of leukocyte adhesion molecule deficiency. Abnormal splicing and a missense mutation in a conserved region of CD18 impair cell surface expression of beta 2 integrins. J Biol Chem. 1992 Feb 15; 267(5):3351-7.
    View in: PubMed
    Score: 0.011
  26. On the regulation of beta 2 integrins. Adv Exp Med Biol. 1992; 323:171-9.
    View in: PubMed
    Score: 0.011
  27. The promoter of the CD11b gene directs myeloid-specific and developmentally regulated expression. Proc Natl Acad Sci U S A. 1991 Dec 01; 88(23):10525-9.
    View in: PubMed
    Score: 0.011
  28. Expression of a soluble and functional form of the human beta 2 integrin CD11b/CD18. Proc Natl Acad Sci U S A. 1991 Apr 15; 88(8):3106-10.
    View in: PubMed
    Score: 0.010
  29. Identity of Wegener's autoantigen (p29) with proteinase 3 and myeloblastin. Blood. 1990 Nov 15; 76(10):2162.
    View in: PubMed
    Score: 0.010
  30. Leukocyte adhesion molecules deficiency: its structural basis, pathophysiology and implications for modulating the inflammatory response. Immunol Rev. 1990 Apr; 114:145-80.
    View in: PubMed
    Score: 0.010
  31. Point mutations impairing cell surface expression of the common beta subunit (CD18) in a patient with leukocyte adhesion molecule (Leu-CAM) deficiency. J Clin Invest. 1990 Mar; 85(3):977-81.
    View in: PubMed
    Score: 0.010
  32. Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules. J Cell Biol. 1989 Dec; 109(6 Pt 2):3435-44.
    View in: PubMed
    Score: 0.009
  33. Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase. Blood. 1989 Nov 01; 74(6):1888-93.
    View in: PubMed
    Score: 0.009
  34. Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J Cell Biol. 1988 Jun; 106(6):2153-8.
    View in: PubMed
    Score: 0.008
  35. Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins. Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2776-80.
    View in: PubMed
    Score: 0.008
  36. Recombinant integrin CD11b A-domain blocks polymorphonuclear cells recruitment and protects against skeletal muscle inflammatory injury in the rat. Immunology. 2006 Dec; 119(4):431-40.
    View in: PubMed
    Score: 0.008
  37. CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD. Blood. 2003 May 15; 101(10):4033-41.
    View in: PubMed
    Score: 0.006
  38. Polycystin-1 activates and stabilizes the polycystin-2 channel. J Biol Chem. 2003 Jan 17; 278(3):1457-62.
    View in: PubMed
    Score: 0.006
  39. Outside-in signaling by lipopolysaccharide through a tailless integrin. J Immunol. 1997 Jul 01; 159(1):433-8.
    View in: PubMed
    Score: 0.004
  40. Two conformations of the integrin A-domain (I-domain): a pathway for activation? Structure. 1995 Dec 15; 3(12):1333-40.
    View in: PubMed
    Score: 0.004
  41. Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18). Cell. 1995 Feb 24; 80(4):631-8.
    View in: PubMed
    Score: 0.003
  42. Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation. Blood. 1991 Oct 01; 78(7):1826-33.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.