Harvard Catalyst Profiles

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M. Amin Arnaout, M.D.

Concepts

This page shows the publications M. Arnaout has written about Models, Molecular.
Connection Strength

0.918
  1. The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18. Blood. 2007 Apr 15; 109(8):3513-20.
    View in: PubMed
    Score: 0.153
  2. Structural Basis of the Differential Binding of Engineered Knottins to Integrins aVß3 and a5ß1. Structure. 2019 09 03; 27(9):1443-1451.e6.
    View in: PubMed
    Score: 0.092
  3. Atomic basis for the species-specific inhibition of aV integrins by monoclonal antibody 17E6 is revealed by the crystal structure of aVß3 ectodomain-17E6 Fab complex. J Biol Chem. 2014 May 16; 289(20):13801-9.
    View in: PubMed
    Score: 0.063
  4. Structural basis for pure antagonism of integrin aVß3 by a high-affinity form of fibronectin. Nat Struct Mol Biol. 2014 Apr; 21(4):383-8.
    View in: PubMed
    Score: 0.063
  5. EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane. PLoS One. 2013; 8(2):e57951.
    View in: PubMed
    Score: 0.059
  6. Crystal structure of the complete integrin alphaVbeta3 ectodomain plus an alpha/beta transmembrane fragment. J Cell Biol. 2009 Aug 24; 186(4):589-600.
    View in: PubMed
    Score: 0.046
  7. Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol. 2007 Oct; 19(5):495-507.
    View in: PubMed
    Score: 0.041
  8. Purification, analysis, and crystal structure of integrins. Methods Enzymol. 2007; 426:307-36.
    View in: PubMed
    Score: 0.038
  9. Integrin structure, allostery, and bidirectional signaling. Annu Rev Cell Dev Biol. 2005; 21:381-410.
    View in: PubMed
    Score: 0.033
  10. Integrins, cations and ligands: making the connection. J Thromb Haemost. 2003 Jul; 1(7):1642-54.
    View in: PubMed
    Score: 0.030
  11. New insights into the structural basis of integrin activation. Blood. 2003 Aug 15; 102(4):1155-9.
    View in: PubMed
    Score: 0.030
  12. Coming to grips with integrin binding to ligands. Curr Opin Cell Biol. 2002 Oct; 14(5):641-51.
    View in: PubMed
    Score: 0.029
  13. Integrin structure: new twists and turns in dynamic cell adhesion. Immunol Rev. 2002 Aug; 186:125-40.
    View in: PubMed
    Score: 0.028
  14. Does the integrin alphaA domain act as a ligand for its betaA domain? Curr Biol. 2002 May 14; 12(10):R340-2.
    View in: PubMed
    Score: 0.028
  15. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science. 2002 Apr 05; 296(5565):151-5.
    View in: PubMed
    Score: 0.027
  16. Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science. 2001 Oct 12; 294(5541):339-45.
    View in: PubMed
    Score: 0.027
  17. An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain. J Biol Chem. 2000 Dec 08; 275(49):38762-7.
    View in: PubMed
    Score: 0.025
  18. Interaction of purified human proteinase 3 (PR3) with reconstituted lipid bilayers. Eur J Biochem. 1999 Apr; 261(1):155-62.
    View in: PubMed
    Score: 0.022
  19. Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures. J Cell Biol. 1998 Dec 14; 143(6):1523-34.
    View in: PubMed
    Score: 0.022
  20. Solvent-accessible residues on the metal ion-dependent adhesion site face of integrin CR3 mediate its binding to the neutrophil inhibitory factor. J Biol Chem. 1996 Jul 05; 271(27):15858-61.
    View in: PubMed
    Score: 0.019
  21. Two conformations of the integrin A-domain (I-domain): a pathway for activation? Structure. 1995 Dec 15; 3(12):1333-40.
    View in: PubMed
    Score: 0.018
  22. On the regulation of beta 2 integrins. Adv Exp Med Biol. 1992; 323:171-9.
    View in: PubMed
    Score: 0.014
  23. Divalent cations and the relationship between alphaA and betaA domains in integrins. Biochem Pharmacol. 2002 Sep; 64(5-6):805-12.
    View in: PubMed
    Score: 0.007
  24. Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18). Cell. 1995 Feb 24; 80(4):631-8.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.