Harvard Catalyst Profiles

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M. Amin Arnaout, M.D.

Concepts

This page shows the publications M. Arnaout has written about Ligands.
Connection Strength

0.874
  1. Integrins, cations and ligands: making the connection. J Thromb Haemost. 2003 Jul; 1(7):1642-54.
    View in: PubMed
    Score: 0.162
  2. EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane. PLoS One. 2013; 8(2):e57951.
    View in: PubMed
    Score: 0.079
  3. Stable coordination of the inhibitory Ca2+ ion at the metal ion-dependent adhesion site in integrin CD11b/CD18 by an antibody-derived ligand aspartate: implications for integrin regulation and structure-based drug design. J Immunol. 2011 Dec 15; 187(12):6393-401.
    View in: PubMed
    Score: 0.072
  4. Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol. 2007 Oct; 19(5):495-507.
    View in: PubMed
    Score: 0.055
  5. The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18. Blood. 2007 Apr 15; 109(8):3513-20.
    View in: PubMed
    Score: 0.052
  6. Binding Affinity of Metal Ions to the CD11b A-domain Is Regulated by Integrin Activation and Ligands. J Biol Chem. 2004 Jun 11; 279(24):25483-8.
    View in: PubMed
    Score: 0.043
  7. New insights into the structural basis of integrin activation. Blood. 2003 Aug 15; 102(4):1155-9.
    View in: PubMed
    Score: 0.040
  8. Coming to grips with integrin binding to ligands. Curr Opin Cell Biol. 2002 Oct; 14(5):641-51.
    View in: PubMed
    Score: 0.039
  9. Integrin structure: new twists and turns in dynamic cell adhesion. Immunol Rev. 2002 Aug; 186:125-40.
    View in: PubMed
    Score: 0.038
  10. Does the integrin alphaA domain act as a ligand for its betaA domain? Curr Biol. 2002 May 14; 12(10):R340-2.
    View in: PubMed
    Score: 0.037
  11. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science. 2002 Apr 05; 296(5565):151-5.
    View in: PubMed
    Score: 0.037
  12. Characterization of a conformationally sensitive murine monoclonal antibody directed to the metal ion-dependent adhesion site face of integrin CD11b. J Immunol. 2002 Feb 01; 168(3):1219-25.
    View in: PubMed
    Score: 0.037
  13. Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science. 2001 Oct 12; 294(5541):339-45.
    View in: PubMed
    Score: 0.036
  14. Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures. J Cell Biol. 1998 Dec 14; 143(6):1523-34.
    View in: PubMed
    Score: 0.030
  15. Integrin-ligand interactions: scratching the surface. Curr Opin Hematol. 1997 Jan; 4(1):67-74.
    View in: PubMed
    Score: 0.026
  16. A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding. Cell. 1993 Mar 26; 72(6):857-67.
    View in: PubMed
    Score: 0.020
  17. On the regulation of beta 2 integrins. Adv Exp Med Biol. 1992; 323:171-9.
    View in: PubMed
    Score: 0.018
  18. Leukocyte adhesion molecules deficiency: its structural basis, pathophysiology and implications for modulating the inflammatory response. Immunol Rev. 1990 Apr; 114:145-80.
    View in: PubMed
    Score: 0.016
  19. Structure and function of the leukocyte adhesion molecules CD11/CD18. Blood. 1990 Mar 01; 75(5):1037-50.
    View in: PubMed
    Score: 0.016
  20. Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin. J Cell Biol. 2005 Mar 28; 168(7):1109-18.
    View in: PubMed
    Score: 0.011
  21. Divalent cations and the relationship between alphaA and betaA domains in integrins. Biochem Pharmacol. 2002 Sep; 64(5-6):805-12.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.