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M. Amin Arnaout, M.D.

Concepts

This page shows the publications M. Arnaout has written about Antibodies, Monoclonal.
Connection Strength

0.588
  1. Prophylactic orthosteric inhibition of leukocyte integrin CD11b/CD18 prevents long-term fibrotic kidney failure in cynomolgus monkeys. Nat Commun. 2017 01 10; 8:13899.
    View in: PubMed
    Score: 0.193
  2. Atomic basis for the species-specific inhibition of aV integrins by monoclonal antibody 17E6 is revealed by the crystal structure of aVß3 ectodomain-17E6 Fab complex. J Biol Chem. 2014 May 16; 289(20):13801-9.
    View in: PubMed
    Score: 0.159
  3. Characterization of a conformationally sensitive murine monoclonal antibody directed to the metal ion-dependent adhesion site face of integrin CD11b. J Immunol. 2002 Feb 01; 168(3):1219-25.
    View in: PubMed
    Score: 0.068
  4. EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane. PLoS One. 2013; 8(2):e57951.
    View in: PubMed
    Score: 0.037
  5. Functional analysis of the beta 2 integrins. Methods Mol Biol. 1999; 129:105-24.
    View in: PubMed
    Score: 0.014
  6. Solvent-accessible residues on the metal ion-dependent adhesion site face of integrin CR3 mediate its binding to the neutrophil inhibitory factor. J Biol Chem. 1996 Jul 05; 271(27):15858-61.
    View in: PubMed
    Score: 0.012
  7. Preventing the infiltration of leukocytes by monoclonal antibody blocks the development of progressive ischemia in rat burns. Plast Reconstr Surg. 1995 Oct; 96(5):1177-85; discussion 1186-7.
    View in: PubMed
    Score: 0.011
  8. Anti-KCA-3, a monoclonal antibody reactive with a rat complement C3 receptor, distinguishes Kupffer cells from other macrophages. J Immunol. 1993 May 01; 150(9):4019-30.
    View in: PubMed
    Score: 0.009
  9. Effect of an anti-Mo1 MAb on ozone-induced airway inflammation and airway hyperresponsiveness in dogs. Am J Physiol. 1992 Dec; 263(6 Pt 1):L723-6.
    View in: PubMed
    Score: 0.009
  10. Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules. J Cell Biol. 1989 Dec; 109(6 Pt 2):3435-44.
    View in: PubMed
    Score: 0.007
  11. Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase. Blood. 1989 Nov 01; 74(6):1888-93.
    View in: PubMed
    Score: 0.007
  12. The relationship between CR3 deficiency and neutrophil actin assembly. Blood. 1989 May 15; 73(7):1973-9.
    View in: PubMed
    Score: 0.007
  13. Relative contribution of the leukocyte molecules Mo1, LFA-1, and p150,95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific. J Cell Physiol. 1988 Nov; 137(2):305-9.
    View in: PubMed
    Score: 0.007
  14. A dysfunctional Mo1 glycoprotein is present on a subline of the KG1 acute myelogenous leukemia cell line. J Immunol. 1987 May 15; 138(10):3549-54.
    View in: PubMed
    Score: 0.006
  15. Two functional domains in the phagocyte membrane glycoprotein Mo1 identified with monoclonal antibodies. J Immunol. 1986 Nov 15; 137(10):3259-63.
    View in: PubMed
    Score: 0.006
  16. Recombinant integrin CD11b A-domain blocks polymorphonuclear cells recruitment and protects against skeletal muscle inflammatory injury in the rat. Immunology. 2006 Dec; 119(4):431-40.
    View in: PubMed
    Score: 0.006
  17. Mo1 surface glycoprotein: structure, function and clinical importance. Pathol Immunopathol Res. 1986; 5(3-5):371-83.
    View in: PubMed
    Score: 0.006
  18. p150/95, Third member of the LFA-1/CR3 polypeptide family identified by anti-Leu M5 monoclonal antibody. Eur J Immunol. 1985 Jul; 15(7):713-8.
    View in: PubMed
    Score: 0.005
  19. Deficiency of a surface membrane glycoprotein (Mo1) in man. J Clin Invest. 1984 Jan; 73(1):153-9.
    View in: PubMed
    Score: 0.005
  20. Inhibition of phagocytosis of complement C3- or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocyte membrane glycoprotein (Mol). J Clin Invest. 1983 Jul; 72(1):171-9.
    View in: PubMed
    Score: 0.005
  21. Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction. J Clin Invest. 1991 Nov; 88(5):1605-12.
    View in: PubMed
    Score: 0.002
  22. Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polymorphonuclear leukocyte adhesion to cytokine-activated human vascular endothelium. J Immunol. 1989 Apr 01; 142(7):2257-63.
    View in: PubMed
    Score: 0.002
  23. Proliferation of highly purified T cells in response to signaling via surface receptors requires cell-cell contact. J Clin Immunol. 1989 Mar; 9(2):151-8.
    View in: PubMed
    Score: 0.002
  24. LFA-1 beta-chain synthesis and degradation in patients with leukocyte-adhesive proteins deficiency. Eur J Immunol. 1987 Mar; 17(3):417-9.
    View in: PubMed
    Score: 0.002
  25. Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence. J Clin Invest. 1984 Aug; 74(2):536-51.
    View in: PubMed
    Score: 0.001
  26. Induction of granulocyte histaminase release by particle-bound complement C3 cleavage products (C3b, C3bi) and IgG. J Immunol. 1983 Jul; 131(1):439-44.
    View in: PubMed
    Score: 0.001
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.