Harvard Catalyst Profiles

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Mark Redston, M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Papke DJ, Yurgelun MB, Noffsinger AE, Turner KO, Genta RM, Redston M. Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas. N Engl J Med. 2022 11 03; 387(18):1714-1716. PMID: 36322852.
    Citations: 1     Fields:    Translation:HumansCells
  2. Slack JC, Redston M, Goldsmith JD, Bousvaros B, Levy Zitomersky N. Giant Filiform Polyposis of the Colon in a 6-Year Old Male With Ulcerative Colitis. J Pediatr Gastroenterol Nutr. 2022 08 01; 75(2):e30. PMID: 35641897.
    Citations:    Fields:    Translation:Humans
  3. Chen W, Zhao L, Agoston A, White A, Mazzola E, Boyle PJ, Deshpande V, Hornick JL, Bueno R, Bass AJ, Enzinger P, Mamon H, Redston M, Patil DT. Florid Foreign Body-type Giant Cell Response to Keratin Is Associated With Improved Overall Survival in Patients Receiving Preoperative Therapy for Esophageal Squamous Cell Carcinoma. Am J Surg Pathol. 2021 12 01; 45(12):1648-1660. PMID: 34469333.
    Citations:    Fields:    Translation:Humans
  4. Redston M, Noffsinger A, Kim A, Akarca FG, Rara M, Stapleton D, Nowden L, Lash R, Bass AJ, Stachler MD. Abnormal TP53 Predicts Risk of Progression in Patients With Barrett's Esophagus Regardless of a Diagnosis of Dysplasia. Gastroenterology. 2022 02; 162(2):468-481. PMID: 34757142; PMCID: PMC9341495.
    Citations: 3     Fields:    Translation:Humans
  5. Stachler MD, Camarda ND, Deitrick C, Kim A, Agoston AT, Odze RD, Hornick JL, Nag A, Thorner AR, Ducar M, Noffsinger A, Lash RH, Redston M, Carter SL, Davison JM, Bass AJ. Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma. Gastroenterology. 2018 07; 155(1):156-167. PMID: 29608884; PMCID: PMC6035092.
    Citations: 38     Fields:    Translation:Humans
  6. Niedzwiecki D, Hasson RM, Lenz HJ, Ye C, Redston M, Ogino S, Fuchs CS, Compton CC, Mayer RJ, Goldberg RM, Colacchio TA, Saltz LB, Warren RS, Bertagnolli MM. A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803. Oncologist. 2017 01; 22(1):107-114. PMID: 27821793.
    Citations: 6     Fields:    Translation:Humans
  7. Jessup CJ, Redston M, Tilton E, Reimann JD. Importance of universal mismatch repair protein immunohistochemistry in patients with sebaceous neoplasia as an initial screening tool for Muir-Torre syndrome. Hum Pathol. 2016 Mar; 49:1-9. PMID: 26826402.
    Citations: 11     Fields:    Translation:HumansCells
  8. McIntire M, Redston M. Targeted therapies and predictive markers in epithelial malignancies of the gastrointestinal tract. Arch Pathol Lab Med. 2012 May; 136(5):496-503. PMID: 22229849.
    Citations: 4     Fields:    Translation:Humans
  9. Bertagnolli MM, Redston M, Compton CC, Niedzwiecki D, Mayer RJ, Goldberg RM, Colacchio TA, Saltz LB, Warren RS. Microsatellite instability and loss of heterozygosity at chromosomal location 18q: prospective evaluation of biomarkers for stages II and III colon cancer--a study of CALGB 9581 and 89803. J Clin Oncol. 2011 Aug 10; 29(23):3153-62. PMID: 21747089.
    Citations: 68     Fields:    Translation:HumansCells
  10. Cho NL, Carothers AM, Rizvi H, Hasson RM, Redston M, Bertagnolli MM. Immunohistochemical and molecular analysis of tyrosine kinase activity in desmoid tumors. J Surg Res. 2012 Apr; 173(2):320-6. PMID: 21195420.
    Citations: 5     Fields:    Translation:HumansCells
  11. Bertagnolli MM, Eagle CJ, Zauber AG, Redston M, Breazna A, Kim K, Tang J, Rosenstein RB, Umar A, Bagheri D, Collins NT, Burn J, Chung DC, Dewar T, Foley TR, Hoffman N, Macrae F, Pruitt RE, Saltzman JR, Salzberg B, Sylwestrowicz T, Hawk ET. Five-year efficacy and safety analysis of the Adenoma Prevention with Celecoxib Trial. Cancer Prev Res (Phila). 2009 Apr; 2(4):310-21. PMID: 19336730.
    Citations: 87     Fields:    Translation:Humans
  12. Bertagnolli MM, Warren RS, Niedzwiecki D, Mueller E, Compton CC, Redston M, Hall M, Hahn HP, Jewell SD, Mayer RJ, Goldberg RM, Saltz LB, Loda M. p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. Clin Cancer Res. 2009 Mar 15; 15(6):2116-22. PMID: 19276255.
    Citations: 8     Fields:    Translation:HumansCells
  13. Bertagnolli MM, Niedzwiecki D, Compton CC, Hahn HP, Hall M, Damas B, Jewell SD, Mayer RJ, Goldberg RM, Saltz LB, Warren RS, Redston M. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. J Clin Oncol. 2009 Apr 10; 27(11):1814-21. PMID: 19273709.
    Citations: 158     Fields:    Translation:HumansCTClinical Trials
  14. Sparr JA, Bandipalliam P, Redston MS, Syngal S. Intraductal papillary mucinous neoplasm of the pancreas with loss of mismatch repair in a patient with Lynch syndrome. Am J Surg Pathol. 2009 Feb; 33(2):309-12. PMID: 18987546; PMCID: PMC2631097.
    Citations: 14     Fields:    Translation:HumansCells
  15. Kulke MH, Hornick JL, Frauenhoffer C, Hooshmand S, Ryan DP, Enzinger PC, Meyerhardt JA, Clark JW, Stuart K, Fuchs CS, Redston MS. O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors. Clin Cancer Res. 2009 Jan 01; 15(1):338-45. PMID: 19118063.
    Citations: 111     Fields:    Translation:Humans
  16. Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, McGrath JP, Protopopova M, Ivanova E, Zhang J, Feng B, Tsao MS, Redston M, Protopopov A, Xiao Y, Futreal PA, Hahn WC, Klimstra DS, Chin L, DePinho RA. Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proc Natl Acad Sci U S A. 2008 Dec 09; 105(49):19372-7. PMID: 19050074; PMCID: PMC2614768.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  17. Bracht LK, Wen P, Meyerhardt JA, Kulke MH, Hornick JL, Redston M, LaFrankie DC, Black PM, Kesari S, Norden A, Drappatz J. DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor. J Clin Oncol. 2008 Oct 10; 26(29):4843-4. PMID: 18779600.
    Citations: 1     Fields:    Translation:Humans
  18. Liau SS, Rocha F, Matros E, Redston M, Whang E. High mobility group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma. Cancer. 2008 Jul 15; 113(2):302-14. PMID: 18473350; PMCID: PMC2997611.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  19. Cleary SP, Kim H, Croitoru ME, Redston M, Knight JA, Gallinger S, Gryfe R. Missense polymorphisms in the adenomatous polyposis coli gene and colorectal cancer risk. Dis Colon Rectum. 2008 Oct; 51(10):1467-73; discussion 1473-4. PMID: 18612690.
    Citations: 5     Fields:    Translation:Humans
  20. Faca VM, Song KS, Wang H, Zhang Q, Krasnoselsky AL, Newcomb LF, Plentz RR, Gurumurthy S, Redston MS, Pitteri SJ, Pereira-Faca SR, Ireton RC, Katayama H, Glukhova V, Phanstiel D, Brenner DE, Anderson MA, Misek D, Scholler N, Urban ND, Barnett MJ, Edelstein C, Goodman GE, Thornquist MD, McIntosh MW, DePinho RA, Bardeesy N, Hanash SM. A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med. 2008 Jun 10; 5(6):e123. PMID: 18547137.
    Citations: 108     Fields:    Translation:HumansAnimals
  21. Singh RS, Grayson W, Redston M, Diwan AH, Warneke CL, McKee PH, Lev D, Lyle S, Calonje E, Lazar AJ. Site and tumor type predicts DNA mismatch repair status in cutaneous sebaceous neoplasia. Am J Surg Pathol. 2008 Jun; 32(6):936-42. PMID: 18551751.
    Citations: 15     Fields:    Translation:HumansCells
  22. Cho NL, Redston M, Zauber AG, Carothers AM, Hornick J, Wilton A, Sontag S, Nishioka N, Giardiello FM, Saltzman JR, Gostout C, Eagle CJ, Hawk ET, Bertagnolli MM. Aberrant crypt foci in the adenoma prevention with celecoxib trial. Cancer Prev Res (Phila). 2008 Jun; 1(1):21-31. PMID: 19138933.
    Citations: 25     Fields:    Translation:Humans
  23. Srivastava A, Redston M, Farraye FA, Yantiss RK, Odze RD. Hyperplastic/serrated polyposis in inflammatory bowel disease: a case series of a previously undescribed entity. Am J Surg Pathol. 2008 Feb; 32(2):296-303. PMID: 18223333.
    Citations: 11     Fields:    Translation:Humans
  24. Martin ES, Tonon G, Sinha R, Xiao Y, Feng B, Kimmelman AC, Protopopov A, Ivanova E, Brennan C, Montgomery K, Kucherlapati R, Bailey G, Redston M, Chin L, DePinho RA. Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types. Cancer Res. 2007 Nov 15; 67(22):10736-43. PMID: 18006816.
    Citations: 39     Fields:    Translation:HumansCells
  25. Srivastava A, Odze RD, Lauwers GY, Redston M, Antonioli DA, Glickman JN. Morphologic features are useful in distinguishing Barrett esophagus from carditis with intestinal metaplasia. Am J Surg Pathol. 2007 Nov; 31(11):1733-41. PMID: 18059231.
    Citations: 19     Fields:    Translation:Humans
  26. Yantiss RK, Oh KY, Chen YT, Redston M, Odze RD. Filiform serrated adenomas: a clinicopathologic and immunophenotypic study of 18 cases. Am J Surg Pathol. 2007 Aug; 31(8):1238-45. PMID: 17667549.
    Citations: 21     Fields:    Translation:HumansCells
  27. Jenkins MA, Hayashi S, O'Shea AM, Burgart LJ, Smyrk TC, Shimizu D, Waring PM, Ruszkiewicz AR, Pollett AF, Redston M, Barker MA, Baron JA, Casey GR, Dowty JG, Giles GG, Limburg P, Newcomb P, Young JP, Walsh MD, Thibodeau SN, Lindor NM, Lemarchand L, Gallinger S, Haile RW, Potter JD, Hopper JL, Jass JR. Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study. Gastroenterology. 2007 Jul; 133(1):48-56. PMID: 17631130; PMCID: PMC2933045.
    Citations: 121     Fields:    Translation:Humans
  28. Cho NL, Javid SH, Carothers AM, Redston M, Bertagnolli MM. Estrogen receptors alpha and beta are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice. Cancer Res. 2007 Mar 01; 67(5):2366-72. PMID: 17332369.
    Citations: 39     Fields:    Translation:AnimalsCells
  29. Bertagnolli MM, Eagle CJ, Zauber AG, Redston M, Solomon SD, Kim K, Tang J, Rosenstein RB, Wittes J, Corle D, Hess TM, Woloj GM, Boisserie F, Anderson WF, Viner JL, Bagheri D, Burn J, Chung DC, Dewar T, Foley TR, Hoffman N, Macrae F, Pruitt RE, Saltzman JR, Salzberg B, Sylwestrowicz T, Gordon GB, Hawk ET. Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med. 2006 Aug 31; 355(9):873-84. PMID: 16943400.
    Citations: 381     Fields:    Translation:HumansPHPublic Health
  30. Carothers AM, Moran AE, Cho NL, Redston M, Bertagnolli MM. Changes in antitumor response in C57BL/6J-Min/+ mice during long-term administration of a selective cyclooxygenase-2 inhibitor. Cancer Res. 2006 Jun 15; 66(12):6432-8. PMID: 16778222.
    Citations: 12     Fields:    Translation:AnimalsCells
  31. Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5947-52. PMID: 16585505; PMCID: PMC1458678.
    Citations: 297     Fields:    Translation:Animals
  32. Carothers AM, Javid SH, Moran AE, Hunt DH, Redston M, Bertagnolli MM. Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility. Exp Cell Res. 2006 Feb 15; 312(4):387-400. PMID: 16368433.
    Citations: 8     Fields:    Translation:AnimalsCells
  33. Matros E, Bailey G, Clancy T, Zinner M, Ashley S, Whang E, Redston M. Cytokeratin 20 expression identifies a subtype of pancreatic adenocarcinoma with decreased overall survival. Cancer. 2006 Feb 01; 106(3):693-702. PMID: 16362976.
    Citations: 12     Fields:    Translation:Humans
  34. Redston M, Compton CC, Miedema BW, Niedzwiecki D, Dowell JM, Jewell SD, Fleshman JM, Bem J, Mayer RJ, Bertagnolli MM. Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001. J Clin Oncol. 2006 Feb 20; 24(6):878-83. PMID: 16418493.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  35. Goel VK, Lazar AJ, Warneke CL, Redston MS, Haluska FG. Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma. J Invest Dermatol. 2006 Jan; 126(1):154-60. PMID: 16417231.
    Citations: 137     Fields:    Translation:Humans
  36. Hruban RH, Adsay NV, Albores-Saavedra J, Anver MR, Biankin AV, Boivin GP, Furth EE, Furukawa T, Klein A, Klimstra DS, Kloppel G, Lauwers GY, Longnecker DS, Luttges J, Maitra A, Offerhaus GJ, Pérez-Gallego L, Redston M, Tuveson DA. Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations. Cancer Res. 2006 Jan 01; 66(1):95-106. PMID: 16397221.
    Citations: 193     Fields:    Translation:HumansAnimals
  37. Bacani J, Zwingerman R, Di Nicola N, Spencer S, Wegrynowski T, Mitchell K, Hay K, Redston M, Holowaty E, Huntsman D, Pollett A, Riddell R, Gallinger S. Tumor microsatellite instability in early onset gastric cancer. J Mol Diagn. 2005 Oct; 7(4):465-77. PMID: 16237216.
    Citations: 27     Fields:    Translation:HumansCells
  38. Duxbury MS, Matros E, Clancy T, Bailey G, Doff M, Zinner MJ, Ashley SW, Maitra A, Redston M, Whang EE. CEACAM6 is a novel biomarker in pancreatic adenocarcinoma and PanIN lesions. Ann Surg. 2005 Mar; 241(3):491-6. PMID: 15729073; PMCID: PMC1356989.
    Citations: 32     Fields:    Translation:Humans
  39. Haskell HD, Haynes HA, McKee PH, Redston M, Granter SR, Lazar AJ. Basal cell carcinoma with matrical differentiation: a case study with analysis of beta-catenin. J Cutan Pathol. 2005 Mar; 32(3):245-50. PMID: 15701088.
    Citations: 2     Fields:    Translation:Humans
  40. Lazar AJ, Calonje E, Grayson W, Dei Tos AP, Mihm MC, Redston M, McKee PH. Pilomatrix carcinomas contain mutations in CTNNB1, the gene encoding beta-catenin. J Cutan Pathol. 2005 Feb; 32(2):148-57. PMID: 15606674.
    Citations: 29     Fields:    Translation:HumansCells
  41. Moran AE, Carothers AM, Weyant MJ, Redston M, Bertagnolli MM. Carnosol inhibits beta-catenin tyrosine phosphorylation and prevents adenoma formation in the C57BL/6J/Min/+ (Min/+) mouse. Cancer Res. 2005 Feb 01; 65(3):1097-104. PMID: 15705912.
    Citations: 30     Fields:    Translation:AnimalsCells
  42. Oh K, Redston M, Odze RD. Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon. Hum Pathol. 2005 Jan; 36(1):101-11. PMID: 15712188.
    Citations: 15     Fields:    Translation:Humans
  43. Lepourcelet M, Tou L, Cai L, Sawada J, Lazar AJ, Glickman JN, Williamson JA, Everett AD, Redston M, Fox EA, Nakatani Y, Shivdasani RA. Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development. 2005 Jan; 132(2):415-27. PMID: 15604097.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  44. Javid SH, Moran AE, Carothers AM, Redston M, Bertagnolli MM. Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer. Carcinogenesis. 2005 Mar; 26(3):587-95. PMID: 15579483.
    Citations: 20     Fields:    Translation:Animals
  45. Croitoru ME, Cleary SP, Di Nicola N, Manno M, Selander T, Aronson M, Redston M, Cotterchio M, Knight J, Gryfe R, Gallinger S. Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk. J Natl Cancer Inst. 2004 Nov 03; 96(21):1631-4. PMID: 15523092.
    Citations: 72     Fields:    Translation:Humans
  46. Haddad R, Ogilvie RT, Croitoru M, Muniz V, Gryfe R, Pollet A, Shanmugathasan P, Fitzgerald T, Law CH, Hanna SS, Jothy S, Redston M, Gallinger S, Smith AJ. Microsatellite instability as a prognostic factor in resected colorectal cancer liver metastases. Ann Surg Oncol. 2004 Nov; 11(11):977-82. PMID: 15525826.
    Citations: 22     Fields:    Translation:HumansCells
  47. Bertagnolli M, Miedema B, Redston M, Dowell J, Niedzwiecki D, Fleshman J, Bem J, Mayer R, Zinner M, Compton C. Sentinel node staging of resectable colon cancer: results of a multicenter study. Ann Surg. 2004 Oct; 240(4):624-8; discussion 628-30. PMID: 15383790; PMCID: PMC1356464.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  48. Swallow CJ, Partridge EA, Macmillan JC, Tajirian T, DiGuglielmo GM, Hay K, Szweras M, Jahnen-Dechent W, Wrana JL, Redston M, Gallinger S, Dennis JW. alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression. Cancer Res. 2004 Sep 15; 64(18):6402-9. PMID: 15374947.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  49. Moran AE, Hunt DH, Javid SH, Redston M, Carothers AM, Bertagnolli MM. Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice. J Biol Chem. 2004 Oct 08; 279(41):43261-72. PMID: 15294912.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  50. Aguirre AJ, Brennan C, Bailey G, Sinha R, Feng B, Leo C, Zhang Y, Zhang J, Gans JD, Bardeesy N, Cauwels C, Cordon-Cardo C, Redston MS, DePinho RA, Chin L. High-resolution characterization of the pancreatic adenocarcinoma genome. Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24):9067-72. PMID: 15199222; PMCID: PMC428474.
    Citations: 117     Fields:    Translation:HumansAnimalsCells
  51. Bookman ID, Redston MS, Greenberg GR. Successful treatment of cap polyposis with infliximab. Gastroenterology. 2004 Jun; 126(7):1868-71. PMID: 15188181.
    Citations: 17     Fields:    Translation:Humans
  52. Kulke MH, Odze RD, Mueller JD, Wang H, Redston M, Bertagnolli MM. Prognostic significance of vascular endothelial growth factor and cyclooxygenase 2 expression in patients receiving preoperative chemoradiation for esophageal cancer. J Thorac Cardiovasc Surg. 2004 Jun; 127(6):1579-86. PMID: 15173710.
    Citations: 12     Fields:    Translation:Humans
  53. Haddad R, Vincent JB, Gryfe R, Kim H, Wen J, Redston M, Scherer SW, Gallinger S. Chromosome 7q31 allelic imbalance and somatic mutations of RAY1/ST7 gene in colorectal cancer. Cancer Lett. 2004 Jan 08; 203(1):87-90. PMID: 14670621.
    Citations: 1     Fields:    Translation:HumansCells
  54. Aguirre AJ, Bardeesy N, Sinha M, Lopez L, Tuveson DA, Horner J, Redston MS, DePinho RA. Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev. 2003 Dec 15; 17(24):3112-26. PMID: 14681207; PMCID: PMC305262.
    Citations: 512     Fields:    Translation:HumansAnimalsCells
  55. Ribic CM, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, Hamilton SR, Laurent-Puig P, Gryfe R, Shepherd LE, Tu D, Redston M, Gallinger S. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med. 2003 Jul 17; 349(3):247-57. PMID: 12867608; PMCID: PMC3584639.
    Citations: 771     Fields:    Translation:HumansCellsCTClinical Trials
  56. Brezden-Masley C, Aronson MD, Bapat B, Pollett A, Gryfe R, Redston M, Gallinger S. Hereditary nonpolyposis colorectal cancer--molecular basis. Surgery. 2003 Jul; 134(1):29-33. PMID: 12874579.
    Citations: 1     Fields:    Translation:HumansCells
  57. Cleary SP, Zhang W, Di Nicola N, Aronson M, Aube J, Steinman A, Haddad R, Redston M, Gallinger S, Narod SA, Gryfe R. Heterozygosity for the BLM(Ash) mutation and cancer risk. Cancer Res. 2003 Apr 15; 63(8):1769-71. PMID: 12702560.
    Citations: 19     Fields:    Translation:Humans
  58. Redston M. Assembling a tumor progression model. Methods Mol Biol. 2003; 223:383-401. PMID: 12777741.
    Citations:    Fields:    Translation:HumansAnimalsCells
  59. Haider MA, Amitai MM, Rappaport DC, O'Malley ME, Hanbidge AE, Redston M, Lockwood GA, Gallinger S. Multi-detector row helical CT in preoperative assessment of small (< or = 1.5 cm) liver metastases: is thinner collimation better? Radiology. 2002 Oct; 225(1):137-42. PMID: 12354997.
    Citations: 24     Fields:    Translation:Humans
  60. Brubaker PL, Drucker DJ, Asa SL, Swallow C, Redston M, Greenberg GR. Prolonged gastrointestinal transit in a patient with a glucagon-like peptide (GLP)-1- and -2-producing neuroendocrine tumor. J Clin Endocrinol Metab. 2002 Jul; 87(7):3078-83. PMID: 12107204.
    Citations: 5     Fields:    Translation:Humans
  61. Park J, Betel D, Gryfe R, Michalickova K, Di Nicola N, Gallinger S, Hogue CW, Redston M. Mutation profiling of mismatch repair-deficient colorectal cncers using an in silico genome scan to identify coding microsatellites. Cancer Res. 2002 Mar 01; 62(5):1284-8. PMID: 11888892.
    Citations: 19     Fields:    Translation:HumansCells
  62. Lindor NM, Burgart LJ, Leontovich O, Goldberg RM, Cunningham JM, Sargent DJ, Walsh-Vockley C, Petersen GM, Walsh MD, Leggett BA, Young JP, Barker MA, Jass JR, Hopper J, Gallinger S, Bapat B, Redston M, Thibodeau SN. Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol. 2002 Feb 15; 20(4):1043-8. PMID: 11844828.
    Citations: 272     Fields:    Translation:HumansCells
  63. Lal G, Ash C, Hay K, Redston M, Kwong E, Hancock B, Mak T, Kargman S, Evans JF, Gallinger S. Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor. Cancer Res. 2001 Aug 15; 61(16):6131-6. PMID: 11507063.
    Citations: 15     Fields:    Translation:AnimalsCells
  64. Thompson-Fawcett MW, Marcus V, Redston M, Cohen Z, McLeod RS. Risk of dysplasia in long-term ileal pouches and pouches with chronic pouchitis. Gastroenterology. 2001 Aug; 121(2):275-81. PMID: 11487537.
    Citations: 22     Fields:    Translation:Humans
  65. Done SJ, Eskandarian S, Bull S, Redston M, Andrulis IL. p53 missense mutations in microdissected high-grade ductal carcinoma in situ of the breast. J Natl Cancer Inst. 2001 May 02; 93(9):700-4. PMID: 11333292.
    Citations: 30     Fields:    Translation:Humans
  66. Redston M. Carcinogenesis in the GI tract: from morphology to genetics and back again. Mod Pathol. 2001 Mar; 14(3):236-45. PMID: 11266532.
    Citations: 9     Fields:    Translation:HumansCells
  67. Thompson-Fawcett MW, Marcus VA, Redston M, Cohen Z, Mcleod RS. Adenomatous polyps develop commonly in the ileal pouch of patients with familial adenomatous polyposis. Dis Colon Rectum. 2001 Mar; 44(3):347-53. PMID: 11289279.
    Citations: 24     Fields:    Translation:Humans
  68. Done SJ, Arneson CR, Ozçelik H, Redston M, Andrulis IL. P53 protein accumulation in non-invasive lesions surrounding p53 mutation positive invasive breast cancers. Breast Cancer Res Treat. 2001 Jan; 65(2):111-8. PMID: 11261826.
    Citations: 9     Fields:    Translation:Humans
  69. Sasaki T, Irie-Sasaki J, Horie Y, Bachmaier K, Fata JE, Li M, Suzuki A, Bouchard D, Ho A, Redston M, Gallinger S, Khokha R, Mak TW, Hawkins PT, Stephens L, Scherer SW, Tsao M, Penninger JM. Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma. Nature. 2000 Aug 24; 406(6798):897-902. PMID: 10972292.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  70. Wilentz RE, Goggins M, Redston M, Marcus VA, Adsay NV, Sohn TA, Kadkol SS, Yeo CJ, Choti M, Zahurak M, Johnson K, Tascilar M, Offerhaus GJ, Hruban RH, Kern SE. Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity. Am J Pathol. 2000 May; 156(5):1641-51. PMID: 10793075; PMCID: PMC1876921.
    Citations: 80     Fields:    Translation:HumansCells
  71. Lal G, Liu L, Hogg D, Lassam NJ, Redston MS, Gallinger S. Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations. Genes Chromosomes Cancer. 2000 Apr; 27(4):358-61. PMID: 10719365.
    Citations: 11     Fields:    Translation:Humans
  72. Lal G, Liu G, Schmocker B, Kaurah P, Ozcelik H, Narod SA, Redston M, Gallinger S. Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations. Cancer Res. 2000 Jan 15; 60(2):409-16. PMID: 10667595.
    Citations: 79     Fields:    Translation:Humans
  73. Gryfe R, Kim H, Hsieh ET, Aronson MD, Holowaty EJ, Bull SB, Redston M, Gallinger S. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med. 2000 Jan 13; 342(2):69-77. PMID: 10631274.
    Citations: 410     Fields:    Translation:HumansCells
  74. Yuan ZQ, Wong N, Foulkes WD, Alpert L, Manganaro F, Andreutti-Zaugg C, Iggo R, Anthony K, Hsieh E, Redston M, Pinsky L, Trifiro M, Gordon PH, Lasko D. A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening. J Med Genet. 1999 Oct; 36(10):790-3. PMID: 10528862; PMCID: PMC3622028.
    Citations: 11     Fields:    Translation:HumansCells
  75. Marcus VA, Madlensky L, Gryfe R, Kim H, So K, Millar A, Temple LK, Hsieh E, Hiruki T, Narod S, Bapat BV, Gallinger S, Redston M. Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors. Am J Surg Pathol. 1999 Oct; 23(10):1248-55. PMID: 10524526.
    Citations: 57     Fields:    Translation:HumansCells
  76. Jiang CY, Esufali S, Berk T, Gallinger S, Cohen Z, Tobi M, Redston M, Bapat B. STK11/LKB1 germline mutations are not identified in most Peutz-Jeghers syndrome patients. Clin Genet. 1999 Aug; 56(2):136-41. PMID: 10517250.
    Citations: 16     Fields:    Translation:HumansCells
  77. Mirabelli-Primdahl L, Gryfe R, Kim H, Millar A, Luceri C, Dale D, Holowaty E, Bapat B, Gallinger S, Redston M. Beta-catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway. Cancer Res. 1999 Jul 15; 59(14):3346-51. PMID: 10416591.
    Citations: 52     Fields:    Translation:HumansCells
  78. Millar AL, Pal T, Madlensky L, Sherman C, Temple L, Mitri A, Cheng H, Marcus V, Gallinger S, Redston M, Bapat B, Narod S. Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium. Hum Mol Genet. 1999 May; 8(5):823-9. PMID: 10196371.
    Citations: 13     Fields:    Translation:HumansCells
  79. Gryfe R, Di Nicola N, Lal G, Gallinger S, Redston M. Inherited colorectal polyposis and cancer risk of the APC I1307K polymorphism. Am J Hum Genet. 1999 Feb; 64(2):378-84. PMID: 9973276; PMCID: PMC1377748.
    Citations: 28     Fields:    Translation:Humans
  80. Bapat BV, Madlensky L, Temple LK, Hiruki T, Redston M, Baron DL, Xia L, Marcus VA, Soravia C, Mitri A, Shen W, Gryfe R, Berk T, Chodirker BN, Cohen Z, Gallinger S. Family history characteristics, tumor microsatellite instability and germline MSH2 and MLH1 mutations in hereditary colorectal cancer. Hum Genet. 1999 Feb; 104(2):167-76. PMID: 10190329.
    Citations: 23     Fields:    Translation:HumansCells
  81. Peralta RC, Casson AG, Wang RN, Keshavjee S, Redston M, Bapat B. Distinct regions of frequent loss of heterozygosity of chromosome 5p and 5q in human esophageal cancer. Int J Cancer. 1998 Nov 23; 78(5):600-5. PMID: 9808529.
    Citations: 12     Fields:    Translation:HumansCells
  82. Gryfe R, Di Nicola N, Gallinger S, Redston M. Somatic instability of the APC I1307K allele in colorectal neoplasia. Cancer Res. 1998 Sep 15; 58(18):4040-3. PMID: 9751605.
    Citations: 19     Fields:    Translation:HumansCells
  83. Redston M, Nathanson KL, Yuan ZQ, Neuhausen SL, Satagopan J, Wong N, Yang D, Nafa D, Abrahamson J, Ozcelik H, Antin-Ozerkis D, Andrulis I, Daly M, Pinsky L, Schrag D, Gallinger S, Kaback M, King MC, Woodage T, Brody LC, Godwin A, Warner E, Weber B, Foulkes W, Offit K. The APCI1307K allele and breast cancer risk. Nat Genet. 1998 Sep; 20(1):13-4. PMID: 9731522.
    Citations: 15     Fields:    Translation:Humans
  84. To MD, Done SJ, Redston M, Andrulis IL. Analysis of mRNA from microdissected frozen tissue sections without RNA isolation. Am J Pathol. 1998 Jul; 153(1):47-51. PMID: 9665464; PMCID: PMC1852932.
    Citations: 10     Fields:    Translation:Humans
  85. Casson AG, Tammemagi M, Eskandarian S, Redston M, McLaughlin J, Ozcelik H. p53 alterations in oesophageal cancer: association with clinicopathological features, risk factors, and survival. Mol Pathol. 1998 Apr; 51(2):71-9. PMID: 9713589; PMCID: PMC395613.
    Citations: 18     Fields:    Translation:Humans
  86. Done SJ, Arneson NC, Ozçelik H, Redston M, Andrulis IL. p53 mutations in mammary ductal carcinoma in situ but not in epithelial hyperplasias. Cancer Res. 1998 Feb 15; 58(4):785-9. PMID: 9485035.
    Citations: 10     Fields:    Translation:Humans
  87. Gryfe R, Swallow C, Bapat B, Redston M, Gallinger S, Couture J. Molecular biology of colorectal cancer. Curr Probl Cancer. 1997 Sep-Oct; 21(5):233-300. PMID: 9438104.
    Citations: 55     Fields:    Translation:Humans
  88. Damani NN, Asch MR, Redston M. The diagnostic challenge of vasculitis in a patient presenting with acute cholecystitis and a focal pancreatic mass: case report. Can Assoc Radiol J. 1997 Jun; 48(3):179-82. PMID: 9193416.
    Citations: 2     Fields:    Translation:Humans
  89. Ozçelik H, Schmocker B, Di Nicola N, Shi XH, Langer B, Moore M, Taylor BR, Narod SA, Darlington G, Andrulis IL, Gallinger S, Redston M. Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients. Nat Genet. 1997 May; 16(1):17-8. PMID: 9140390.
    Citations: 62     Fields:    Translation:Humans
  90. Asch MR, Yu J, Margolis M, Redston M. Adenomyoma of the common bile duct imaged with endoscopic ultrasonography: case report. Can Assoc Radiol J. 1997 Apr; 48(2):101-4. PMID: 9146466.
    Citations: 3     Fields:    Translation:Humans
  91. Madlensky L, Bapat B, Redston M, Pearl R, Gallinger S, Cohen Z. Using genetic information to make surgical decisions: report of a case of a 13-year-old boy with colon cancer. Dis Colon Rectum. 1997 Feb; 40(2):240-3. PMID: 9075764.
    Citations: 1     Fields:    Translation:HumansCells
  92. Reitmair AH, Redston M, Cai JC, Chuang TC, Bjerknes M, Cheng H, Hay K, Gallinger S, Bapat B, Mak TW. Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice. Cancer Res. 1996 Aug 15; 56(16):3842-9. PMID: 8706033.
    Citations: 45     Fields:    Translation:AnimalsCells
  93. Reitmair AH, Cai JC, Bjerknes M, Redston M, Cheng H, Pind MT, Hay K, Mitri A, Bapat BV, Mak TW, Gallinger S. MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis. Cancer Res. 1996 Jul 01; 56(13):2922-6. PMID: 8674041.
    Citations: 49     Fields:    Translation:AnimalsCells
  94. Redston MS, Wanless IR. The hepatic von Meyenburg complex: prevalence and association with hepatic and renal cysts among 2843 autopsies [corrected]. Mod Pathol. 1996 Mar; 9(3):233-7. PMID: 8685220.
    Citations: 43     Fields:    Translation:Humans
  95. Hahn SA, Seymour AB, Hoque AT, Schutte M, da Costa LT, Redston MS, Caldas C, Weinstein CL, Fischer A, Yeo CJ, et al. Allelotype of pancreatic adenocarcinoma using xenograft enrichment. Cancer Res. 1995 Oct 15; 55(20):4670-5. PMID: 7553647.
    Citations: 85     Fields:    Translation:Animals
  96. DiGiuseppe JA, Redston MS, Yeo CJ, Kern SE, Hruban RH. p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. Am J Pathol. 1995 Oct; 147(4):884-8. PMID: 7573363; PMCID: PMC1871020.
    Citations: 25     Fields:    Translation:Humans
  97. Reitmair AH, Schmits R, Ewel A, Bapat B, Redston M, Mitri A, Waterhouse P, Mittrücker HW, Wakeham A, Liu B, et al. MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nat Genet. 1995 Sep; 11(1):64-70. PMID: 7550317.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  98. Madlensky L, Berk TC, Bapat BV, McLeod RS, Couture J, Baron D, Hiruki T, Redston M, Cohen Z, Gallinger S. A preventive registry for hereditary nonpolyposis colorectal cancer. Can J Oncol. 1995 Jul; 5(2):355-60. PMID: 8853507.
    Citations: 5     Fields:    Translation:Humans
  99. Redston MS, Papadopoulos N, Caldas C, Kinzler KW, Kern SE. Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias. Gastroenterology. 1995 Feb; 108(2):383-92. PMID: 7835579.
    Citations: 36     Fields:    Translation:HumansCells
  100. Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruban RH, Yeo CJ, Kern SE. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet. 1994 Sep; 8(1):27-32. PMID: 7726912.
    Citations: 278     Fields:    Translation:HumansCells
  101. Redston MS, Kern SE. Klenow co-sequencing: a method for eliminating "stops". Biotechniques. 1994 Aug; 17(2):286, 288. PMID: 7980928.
    Citations: 4     Fields:    
  102. Kern SE, Redston M, Seymour AB, Caldas C, Powell SM, Kornacki S, Kinzler KW. Molecular genetic profiles of colitis-associated neoplasms. Gastroenterology. 1994 Aug; 107(2):420-8. PMID: 8039618.
    Citations: 40     Fields:    Translation:Humans
  103. Caldas C, Hahn SA, Hruban RH, Redston MS, Yeo CJ, Kern SE. Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. Cancer Res. 1994 Jul 01; 54(13):3568-73. PMID: 8012983.
    Citations: 91     Fields:    Translation:HumansCells
  104. Redston MS, Caldas C, Seymour AB, Hruban RH, da Costa L, Yeo CJ, Kern SE. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res. 1994 Jun 01; 54(11):3025-33. PMID: 8187092.
    Citations: 142     Fields:    Translation:HumansAnimalsCells
  105. Seymour AB, Hruban RH, Redston M, Caldas C, Powell SM, Kinzler KW, Yeo CJ, Kern SE. Allelotype of pancreatic adenocarcinoma. Cancer Res. 1994 May 15; 54(10):2761-4. PMID: 8168108.
    Citations: 53     Fields:    Translation:Humans
  106. Rabkin SW, Redston M. The effect of inhibitors of endogenous opioid degradation, bacitracin, bestatin, captopril, and D-phenylalanine, on digoxin-induced arrhythmias in guinea pigs. Can J Physiol Pharmacol. 1989 Aug; 67(8):857-63. PMID: 2688852.
    Citations: 1     Fields:    Translation:Animals
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