Harvard Catalyst Profiles

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Stefano Bonini, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Di Zazzo A, Yang W, Coassin M, Micera A, Antonini M, Piccinni F, De Piano M, Kohler I, Harms AC, Hankemeier T, Bonini S, Mashaghi A. Correction to: Signaling lipids as diagnostic biomarkers for ocular surface cicatrizing conjunctivitis. J Mol Med (Berl). 2020 Jun 10. PMID: 32524172.
  2. Erickson S, Sullivan AG, Barabino S, Begovic E, Benitez-Del-Castillo JM, Bonini S, Borges JS, Brzheskiy V, Bulat N, Cerim A, Craig P, Cu?nir V, Cu?nir V, Cu?nir V, Doan S, Dülger E, Farrant S, Geerling G, Goldblum D, Golubev S, Gomes JAP, González-Méijome JM, Grupcheva CN, Gündüz ÖU, Horwath-Winter J, Källmark F, Karanadze N, Karcic HH, Karcic S, Kontadakis G, Messmer EM, Mrugacz M, Murphy C, O'Leary OE, Procopciuc V, Pult H, Raus P, Sahin A, Setälä N, Stanila A, Stanila DM, Utheim TP, Vehof J, Versura P, Villani E, Willcox MDP, Wolffsohn JS, Zagórski Z, Zoega GM, Sullivan DA, Gomes JAP, Versura P, Willcox MDP. TFOS European ambassador meeting: Unmet needs and future scientific and clinical solutions for ocular surface diseases. Ocul Surf. 2020 Jun 03. PMID: 32504856.
  3. Micera A, Jirsova K, Esposito G, Balzamino BO, Di Zazzo A, Bonini S. Mast Cells Populate the Corneoscleral Limbus: New Insights for Our Understanding of Limbal Microenvironment. Invest Ophthalmol Vis Sci. 2020 03 09; 61(3):43. PMID: 32207813.
  4. Woodward AM, Di Zazzo A, Bonini S, Argüeso P. Endoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface. Sci Rep. 2020 Feb 10; 10(1):2216. PMID: 32042069.
  5. Spelta S, Di Zazzo A, Antonini M, Bonini S, Coassin M. Does Endogenous Endophthalmitis Need a More Aggressive Treatment? Ocul Immunol Inflamm. 2020 Jan 17; 1-7. PMID: 31951759.
  6. Di Zazzo A, Coassin M, Varacalli G, Galvagno E, De Vincentis A, Bonini S. Neurotrophic keratopathy: Pros and cons of current treatments. Ocul Surf. 2019 10; 17(4):619-623. PMID: 31526824.
  7. Bron AJ, de Paiva CS, Chauhan SK, Bonini S, Gabison EE, Jain S, Knop E, Markoulli M, Ogawa Y, Perez V, Uchino Y, Yokoi N, Zoukhri D, Sullivan DA. Corrigendum to "TFOS DEWS II pathophysiology report" [Ocul. Surf. 15 (3) (2017) 438-510]. Ocul Surf. 2019 Oct; 17(4):842. PMID: 31401339.
  8. Coassin M, Mori T, Di Zazzo A, Sgrulletta R, Varacalli G, Bonini S. Lamellar macular holes: monitoring and management strategies. Clin Ophthalmol. 2019; 13:1173-1182. PMID: 31371914.
  9. Di Zazzo A, Micera A, De Piano M, Coassin M, Sharma S, Bonini S, Fernandes M. Adult Vernal Keratoconjunctivitis: Clinical and biochemical profile of a rare disease. Ocul Surf. 2019 10; 17(4):737-742. PMID: 31276829.
  10. Di Zazzo A, Micera A, Coassin M, Varacalli G, Foulsham W, De Piano M, Bonini S. InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers. Invest Ophthalmol Vis Sci. 2019 04 01; 60(5):1769-1775. PMID: 31022299.
  11. Bonini S, Lambiase A. Reply. Ophthalmology. 2019 02; 126(2):e15-e16. PMID: 30683187.
    Citations:    Fields:    
  12. Di Zazzo A, Micera A, De Piano M, Cortes M, Bonini S. Tears and ocular surface disorders: Usefulness of biomarkers. J Cell Physiol. 2019 07; 234(7):9982-9993. PMID: 30515814.
    Citations:    Fields:    
  13. Woodward AM, Lehoux S, Mantelli F, Di Zazzo A, Brockhausen I, Bonini S, Argüeso P. Inflammatory Stress Causes N-Glycan Processing Deficiency in Ocular Autoimmune Disease. Am J Pathol. 2019 02; 189(2):283-294. PMID: 30448401.
    Citations:    Fields:    
  14. Bonini S, Lambiase A, Rama P, Filatori I, Allegretti M, Chao W, Mantelli F. Phase I Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis. Ophthalmology. 2018 09; 125(9):1468-1471. PMID: 29653861.
    Citations:    Fields:    
  15. Bonini S, Lambiase A, Rama P, Sinigaglia F, Allegretti M, Chao W, Mantelli F. Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis. Ophthalmology. 2018 09; 125(9):1332-1343. PMID: 29653858.
    Citations:    Fields:    
  16. Micera A, Di Zazzo A, Esposito G, Longo R, Foulsham W, Sacco R, Sgrulletta R, Bonini S. Age-Related Changes to Human Tear Composition. Invest Ophthalmol Vis Sci. 2018 04 01; 59(5):2024-2031. PMID: 29677365.
    Citations:    Fields:    Translation:Humans
  17. Di Zazzo A, Roberti G, Mashaghi A, Abud TB, Pavese D, Bonini S. Use of Topical Cannabinomimetic Palmitoylethanolamide in Ocular Surface Disease Associated with Antiglaucoma Medications. J Ocul Pharmacol Ther. 2017 11; 33(9):670-677. PMID: 29045169.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  18. Bron AJ, de Paiva CS, Chauhan SK, Bonini S, Gabison EE, Jain S, Knop E, Markoulli M, Ogawa Y, Perez V, Uchino Y, Yokoi N, Zoukhri D, Sullivan DA. TFOS DEWS II pathophysiology report. Ocul Surf. 2017 07; 15(3):438-510. PMID: 28736340.
    Citations: 21     Fields:    Translation:Humans
  19. Busanello A, Santucci D, Bonini S, Micera A. Review: Environmental impact on ocular surface disorders: Possible epigenetic mechanism modulation and potential biomarkers. Ocul Surf. 2017 10; 15(4):680-687. PMID: 28572031.
    Citations: 1     Fields:    Translation:HumansCells
  20. Baudouin C, Irkeç M, Messmer EM, Benítez-Del-Castillo JM, Bonini S, Figueiredo FC, Geerling G, Labetoulle M, Lemp M, Rolando M, Van Setten G, Aragona P. Clinical impact of inflammation in dry eye disease: proceedings of the ODISSEY group meeting. Acta Ophthalmol. 2018 Mar; 96(2):111-119. PMID: 28390092.
    Citations: 2     Fields:    Translation:HumansAnimals
  21. Di Zazzo A, Bonini S, Crugliano S, Fortunato M. The challenging management of pediatric corneal transplantation: an overview of surgical and clinical experiences. Jpn J Ophthalmol. 2017 May; 61(3):207-217. PMID: 28374268.
    Citations:    Fields:    Translation:Humans
  22. Baudouin C, Figueiredo FC, Messmer EM, Ismail D, Amrane M, Garrigue JS, Bonini S, Leonardi A. A randomized study of the efficacy and safety of 0.1% cyclosporine A cationic emulsion in treatment of moderate to severe dry eye. Eur J Ophthalmol. 2017 Aug 30; 27(5):520-530. PMID: 28362054.
    Citations: 5     Fields:    Translation:Humans
  23. Oddone F, Roberti G, Micera A, Busanello A, Bonini S, Quaranta L, Agnifili L, Manni G. Exploring Serum Levels of Brain Derived Neurotrophic Factor and Nerve Growth Factor Across Glaucoma Stages. PLoS One. 2017; 12(1):e0168565. PMID: 28068360.
    Citations: 4     Fields:    Translation:HumansCells
  24. Sabatino F, Di Zazzo A, De Simone L, Bonini S. The Intriguing Role of Neuropeptides at the Ocular Surface. Ocul Surf. 2017 01; 15(1):2-14. PMID: 27840126.
    Citations: 1     Fields:    Translation:HumansCells
  25. Micera A, Di Zazzo A, Esposito G, Sgrulletta R, Calder VL, Bonini S. Quiescent and Active Tear Protein Profiles to Predict Vernal Keratoconjunctivitis Reactivation. Biomed Res Int. 2016; 2016:9672082. PMID: 26989694.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  26. Annibali O, Sabatino F, Mantelli F, Olimpieri OM, Bonini S, Avvisati G. Review article: Mucosa-associated lymphoid tissue (MALT)-type lymphoma of ocular adnexa. Biology and treatment. Crit Rev Oncol Hematol. 2016 Apr; 100:37-45. PMID: 26857986.
    Citations: 1     Fields:    Translation:Humans
  27. Micera A, Stampachiacchiere B, Di Zazzo A, Sgrulletta R, Cortes M, Normando EM, Lambiase A, Bonini S. NGF Modulates trkANGFR/p75NTR in aSMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP). PLoS One. 2015; 10(11):e0142737. PMID: 26569118.
    Citations: 1     Fields:    Translation:HumansCells
  28. Mantelli F, Moretti C, Macchi I, Massaro-Giordano G, Cozzupoli GM, Lambiase A, Bonini S. Effects of Sex Hormones on Ocular Surface Epithelia: Lessons Learned From Polycystic Ovary Syndrome. J Cell Physiol. 2016 May; 231(5):971-5. PMID: 26491950.
    Citations: 3     Fields:    Translation:Humans
  29. Annibali O, Chiodi F, Sarlo C, Cortes M, Quaranta-Leoni FM, Quattrocchi C, Bianchi A, Bonini S, Avvisati G. Rituximab as Single Agent in Primary MALT Lymphoma of the Ocular Adnexa. Biomed Res Int. 2015; 2015:895105. PMID: 26425558.
    Citations: 2     Fields:    Translation:Humans
  30. Micera A, Balzamino BO, Di Zazzo A, Biamonte F, Sica G, Bonini S. Toll-Like Receptors and Tissue Remodeling: The Pro/Cons Recent Findings. J Cell Physiol. 2016 Mar; 231(3):531-44. PMID: 26248215.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  31. Mantelli F, Lambiase A, Sacchetti M, Orlandi V, Rosa A, Casella P, Bonini S. Cocaine snorting may induce ocular surface damage through corneal sensitivity impairment. Graefes Arch Clin Exp Ophthalmol. 2015 May; 253(5):765-72. PMID: 25644620.
    Citations: 2     Fields:    Translation:Humans
  32. Sacchetti M, Lambiase A, Moretti C, Mantelli F, Bonini S. Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis. J Immunol Res. 2015; 2015:945317. PMID: 25756057.
    Citations: 2     Fields:    Translation:Humans
  33. Sacchetti M, Scorcia V, Lambiase A, Bonini S. Preliminary evidence of neuropeptides involvement in keratoconus. Acta Ophthalmol. 2015 Jun; 93(4):e315-6. PMID: 25042399.
    Citations:    Fields:    Translation:Humans
  34. Marchesi F, Cirillo M, Bianchi A, Gately M, Olimpieri OM, Cerchiara E, Renzi D, Micera A, Balzamino BO, Bonini S, Onetti Muda A, Avvisati G. High density of CD68+/CD163+ tumour-associated macrophages (M2-TAM) at diagnosis is significantly correlated to unfavorable prognostic factors and to poor clinical outcomes in patients with diffuse large B-cell lymphoma. Hematol Oncol. 2015 Jun; 33(2):110-2. PMID: 24711044.
    Citations: 14     Fields:    Translation:HumansCells
  35. Baudouin C, Aragona P, Van Setten G, Rolando M, Irkeç M, Benítez del Castillo J, Geerling G, Labetoulle M, Bonini S. Diagnosing the severity of dry eye: a clear and practical algorithm. Br J Ophthalmol. 2014 Sep; 98(9):1168-76. PMID: 24627252.
    Citations: 17     Fields:    Translation:Humans
  36. Quaranta-Leoni FM, Moretti C, Sposato S, Nardoni S, Lambiase A, Bonini S. Management of porous orbital implants requiring explantation: a clinical and histopathological study. Ophthalmic Plast Reconstr Surg. 2014 Mar-Apr; 30(2):132-6. PMID: 24614545.
    Citations: 1     Translation:Humans
  37. Sacchetti M, Mantelli F, Lambiase A, Mastropasqua A, Merlo D, Bonini S. Systematic review of randomised clinical trials on topical ciclosporin A for the treatment of dry eye disease. Br J Ophthalmol. 2014 Aug; 98(8):1016-22. PMID: 24344232.
    Citations: 9     Fields:    Translation:Humans
  38. Micera A, Jirsova K, Normando EM, Stampachiacchiere B, Esposito G, Lambiase A, Bonini S. Molecular and biochemical expression of TLRs in human amniotic membrane: a comparative study of fresh and cryopreserved specimens. Graefes Arch Clin Exp Ophthalmol. 2014 Feb; 252(2):267-74. PMID: 24337432.
    Citations:    Fields:    Translation:Humans
  39. Lambiase A, Sacchetti M, Mastropasqua A, Bonini S. Corneal changes in neurosurgically induced neurotrophic keratitis. JAMA Ophthalmol. 2013 Dec; 131(12):1547-53. PMID: 24158681.
    Citations: 11     Fields:    Translation:Humans
  40. Mantelli F, Massaro-Giordano M, Macchi I, Lambiase A, Bonini S. The cellular mechanisms of dry eye: from pathogenesis to treatment. J Cell Physiol. 2013 Dec; 228(12):2253-6. PMID: 23696296.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  41. Leonardi A, Bonini S. Is visual function affected in severe ocular allergies? Curr Opin Allergy Clin Immunol. 2013 Oct; 13(5):558-62. PMID: 23974686.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  42. Mantelli F, Calder VL, Bonini S. The anti-inflammatory effects of therapies for ocular allergy. J Ocul Pharmacol Ther. 2013 Nov; 29(9):786-93. PMID: 24044620.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  43. Barabino S, Rolando M, Nardi M, Bonini S, Aragona P, Traverso CE. The effect of an artificial tear combining hyaluronic acid and tamarind seeds polysaccharide in patients with moderate dry eye syndrome: a new treatment for dry eye. Eur J Ophthalmol. 2014 Mar-Apr; 24(2):173-8. PMID: 24030535.
    Citations: 6     Fields:    Translation:HumansAnimals
  44. Mantelli F, Di Zazzo A, Sacchetti M, Dianzani C, Lambiase A, Bonini S. Topical azithromycin as a novel treatment for ocular rosacea. Ocul Immunol Inflamm. 2013 Oct; 21(5):371-7. PMID: 23875944.
    Citations: 4     Fields:    Translation:Humans
  45. Rocha EM, Mantelli F, Nominato LF, Bonini S. Hormones and dry eye syndrome: an update on what we do and don't know. Curr Opin Ophthalmol. 2013 Jul; 24(4):348-55. PMID: 23680756.
    Citations: 8     Fields:    Translation:Humans
  46. Blanco-Mezquita T, Martinez-Garcia C, Proença R, Zieske JD, Bonini S, Lambiase A, Merayo-Lloves J. Nerve growth factor promotes corneal epithelial migration by enhancing expression of matrix metalloprotease-9. Invest Ophthalmol Vis Sci. 2013 Jun 04; 54(6):3880-90. PMID: 23640040.
    Citations: 18     Fields:    Translation:AnimalsCells
  47. Pellegrini G, Rama P, Matuska S, Lambiase A, Bonini S, Pocobelli A, Colabelli RG, Spadea L, Fasciani R, Balestrazzi E, Vinciguerra P, Rosetta P, Tortori A, Nardi M, Gabbriellini G, Traverso CE, Macaluso C, Losi L, Percesepe A, Venturi B, Corradini F, Panaras A, Di Rocco A, Guatelli P, De Luca M. Biological parameters determining the clinical outcome of autologous cultures of limbal stem cells. Regen Med. 2013 Sep; 8(5):553-67. PMID: 23725042.
    Citations: 23     Fields:    Translation:HumansCellsCTClinical Trials
  48. Leonardi A, Lazzarini D, Motterle L, Bortolotti M, Deligianni V, Curnow SJ, Bonini S, Fregona IA. Vernal keratoconjunctivitis-like disease in adults. Am J Ophthalmol. 2013 May; 155(5):796-803. PMID: 23352342.
    Citations: 3     Fields:    Translation:HumansCells
  49. Lambiase A, Aloe L, Mantelli F, Sacchetti M, Perrella E, Bianchi P, Rocco ML, Bonini S. Capsaicin-induced corneal sensory denervation and healing impairment are reversed by NGF treatment. Invest Ophthalmol Vis Sci. 2012 Dec 17; 53(13):8280-7. PMID: 23154458.
    Citations: 11     Fields:    Translation:Animals
  50. Micera A, Puxeddu I, Balzamino BO, Bonini S, Levi-Schaffer F. Chronic nerve growth factor exposure increases apoptosis in a model of in vitro induced conjunctival myofibroblasts. PLoS One. 2012; 7(10):e47316. PMID: 23071784.
    Citations: 7     Fields:    Translation:HumansCells
  51. Enríquez-de-Salamanca A, Bonini S, Calonge M. Molecular and cellular biomarkers in dry eye disease and ocular allergy. Curr Opin Allergy Clin Immunol. 2012 Oct; 12(5):523-33. PMID: 22895048.
    Citations: 7     Fields:    
  52. Lambiase A, Sacchetti M, Bonini S. Nerve growth factor therapy for corneal disease. Curr Opin Ophthalmol. 2012 Jul; 23(4):296-302. PMID: 22543481.
    Citations: 12     Fields:    Translation:HumansAnimals
  53. Mantelli F, Lambiase A, Di Zazzo A, Bonini S. Sands of sahara after LASIK in avellino corneal dystrophy. Case Rep Ophthalmol Med. 2012; 2012:413010. PMID: 22606493.
  54. Mantelli F, Tranchina L, Lambiase A, Bonini S. Ocular surface damage by ophthalmic compounds. Curr Opin Allergy Clin Immunol. 2011 Oct; 11(5):464-70. PMID: 21822131.
    Citations: 5     Fields:    Translation:Humans
  55. Lambiase A, Leonardi A, Sacchetti M, Deligianni V, Sposato S, Bonini S. Topical cyclosporine prevents seasonal recurrences of vernal keratoconjunctivitis in a randomized, double-masked, controlled 2-year study. J Allergy Clin Immunol. 2011 Oct; 128(4):896-897.e9. PMID: 21868078.
    Citations: 5     Fields:    Translation:Humans
  56. Lambiase A, Micera A, Sacchetti M, Cortes M, Mantelli F, Bonini S. Alterations of tear neuromediators in dry eye disease. Arch Ophthalmol. 2011 Aug; 129(8):981-6. PMID: 21825181.
    Citations: 19     Fields:    Translation:Humans
  57. Lambiase A, Mantelli F, Sacchetti M, Rossi S, Aloe L, Bonini S. Clinical applications of NGF in ocular diseases. Arch Ital Biol. 2011 Jun; 149(2):283-92. PMID: 21702001.
    Citations: 14     Fields:    Translation:Humans
  58. Lambiase A, Micera A, Sacchetti M, Mantelli F, Bonini S. Toll-like receptors in ocular surface diseases: overview and new findings. Clin Sci (Lond). 2011 May; 120(10):441-50. PMID: 21271987.
    Citations: 14     Fields:    Translation:Humans
  59. Sacchetti M, Micera A, Lambiase A, Speranza S, Mantelli F, Petrachi G, Bonini S, Bonini S. Tear levels of neuropeptides increase after specific allergen challenge in allergic conjunctivitis. Mol Vis. 2011 Jan 07; 17:47-52. PMID: 21245958.
    Citations: 9     Fields:    Translation:HumansAnimals
  60. Mantelli F, Micera A, Sacchetti M, Bonini S. Neurogenic inflammation of the ocular surface. Curr Opin Allergy Clin Immunol. 2010 Oct; 10(5):498-504. PMID: 20706114.
    Citations: 4     Fields:    Translation:HumansCells
  61. Lambiase A, Mantelli F, Bonini S. Nerve growth factor eye drops to treat glaucoma. Drug News Perspect. 2010 Jul-Aug; 23(6):361-7. PMID: 20697603.
    Citations: 3     Fields:    Translation:HumansAnimals
  62. Sacchetti M, Lambiase A, Mantelli F, Deligianni V, Leonardi A, Bonini S. Tailored approach to the treatment of vernal keratoconjunctivitis. Ophthalmology. 2010 Jul; 117(7):1294-9. PMID: 20382430.
    Citations: 7     Fields:    Translation:Humans
  63. Sacchetti M, Lambiase A, Coassin M, Bonini S, Bonini S. Toxic corneal ulcer: a frequent and sight-threatening disease. Eur J Ophthalmol. 2009 Nov-Dec; 19(6):916-22. PMID: 19882588.
    Citations: 2     Fields:    Translation:Humans
  64. Micera A, Stampachiacchiere B, Normando EM, Lambiase A, Bonini S, Bonini S. Nerve growth factor modulates toll-like receptor (TLR) 4 and 9 expression in cultured primary VKC conjunctival epithelial cells. Mol Vis. 2009 Oct 13; 15:2037-44. PMID: 19844589.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  65. Mantelli F, Lambiase A, Bonini S. A simple and rapid diagnostic algorithm for the detection of ocular allergic diseases. Curr Opin Allergy Clin Immunol. 2009 Oct; 9(5):471-6. PMID: 19638928.
    Citations: 2     Fields:    Translation:Humans
  66. Lambiase A, Micera A, Bonini S. Multiple action agents and the eye: do they really stabilize mast cells? Curr Opin Allergy Clin Immunol. 2009 Oct; 9(5):454-65. PMID: 19652595.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  67. Iovieno A, Lambiase A, Micera A, Stampachiacchiere B, Sgrulletta R, Bonini S. In vivo characterization of doxycycline effects on tear metalloproteinases in patients with chronic blepharitis. Eur J Ophthalmol. 2009 Sep-Oct; 19(5):708-16. PMID: 19787586.
    Citations: 12     Fields:    Translation:HumansCells
  68. Lambiase A, Aloe L, Centofanti M, Parisi V, Báo SN, Mantelli F, Colafrancesco V, Manni GL, Bucci MG, Bonini S, Levi-Montalcini R. Experimental and clinical evidence of neuroprotection by nerve growth factor eye drops: Implications for glaucoma. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13469-74. PMID: 19805021.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  69. Iovieno A, Lambiase A, Moretti C, Perrella E, Bonini S. Therapeutic effect of topical 5-fluorouracil in conjunctival squamous carcinoma is associated with changes in matrix metalloproteinases and tissue inhibitor of metalloproteinases expression. Cornea. 2009 Aug; 28(7):821-4. PMID: 19574900.
    Citations: 3     Fields:    Translation:Humans
  70. Lambiase A, Micera A, Mantelli F, Moretti C, Di Zazzo A, Perrella E, Bonini S, Bonini S. T-helper 17 lymphocytes in ocular cicatricial pemphigoid. Mol Vis. 2009 Jul 28; 15:1449-55. PMID: 19641634.
    Citations: 8     Fields:    Translation:HumansCells
  71. Lambiase A, Micera A, Pellegrini G, Merlo D, Rama P, De Luca M, Bonini S, Bonini S. In vitro evidence of nerve growth factor effects on human conjunctival epithelial cell differentiation and mucin gene expression. Invest Ophthalmol Vis Sci. 2009 Oct; 50(10):4622-30. PMID: 19407015.
    Citations: 11     Fields:    Translation:HumansCells
  72. Pantano F, Silletta M, Iovieno A, Vincenzi B, Santini D, Galluzzo S, Bonini S, Tonini G. Stevens-Johnson syndrome associated with reduced tear production complicating the use of cetuximab and panitunumab. Int J Colorectal Dis. 2009 Oct; 24(10):1247-8. PMID: 19225787.
    Citations: 2     Fields:    Translation:Humans
  73. Lambiase A, Minchiotti S, Leonardi A, Secchi AG, Rolando M, Calabria G, Orsoni J, Zola E, Ferreri G, Aragona P, Reibaldi A, Chisari G, Bonini S. Prospective, multicenter demographic and epidemiological study on vernal keratoconjunctivitis: a glimpse of ocular surface in Italian population. Ophthalmic Epidemiol. 2009 Jan-Feb; 16(1):38-41. PMID: 19191180.
    Citations: 8     Fields:    Translation:Humans
  74. Micera A, Lambiase A, Bonini S. The role of neuromediators in ocular allergy. Curr Opin Allergy Clin Immunol. 2008 Oct; 8(5):466-71. PMID: 18769203.
    Citations: 6     Fields:    Translation:Humans
  75. Coassin M, Lambiase A, Sposato V, Micera A, Bonini S, Aloe L. Retinal p75 and bax overexpression is associated with retinal ganglion cells apoptosis in a rat model of glaucoma. Graefes Arch Clin Exp Ophthalmol. 2008 Dec; 246(12):1743-9. PMID: 18751719.
    Citations: 21     Fields:    Translation:AnimalsCells
  76. Minchiotti S, Stampachiacchiere B, Micera A, Lambiase A, Ripandelli G, Billi B, Bonini S. Human idiopathic epiretinal membranes express NGF and NGF receptors. Retina. 2008 Apr; 28(4):628-37. PMID: 18398367.
    Citations: 8     Fields:    Translation:HumansCells
  77. Iovieno A, Lambiase A, Sacchetti M, Stampachiacchiere B, Micera A, Bonini S. Preliminary evidence of the efficacy of probiotic eye-drop treatment in patients with vernal keratoconjunctivitis. Graefes Arch Clin Exp Ophthalmol. 2008 Mar; 246(3):435-41. PMID: 18040708.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  78. Bonini S, Sacchetti M, Mantelli F, Lambiase A. Clinical grading of vernal keratoconjunctivitis. Curr Opin Allergy Clin Immunol. 2007 Oct; 7(5):436-41. PMID: 17873585.
    Citations: 11     Fields:    Translation:Humans
  79. Lambiase A, Normando EM, Vitiello L, Micera A, Sacchetti M, Perrella E, Racioppi L, Bonini S, Bonini S. Natural killer cells in vernal keratoconjunctivitis. Mol Vis. 2007 Aug 30; 13:1562-7. PMID: 17893656.
    Citations: 4     Fields:    Translation:HumansCells
  80. Sacchetti M, Baiardini I, Lambiase A, Aronni S, Fassio O, Gramiccioni C, Bonini S, Bonini S. Development and testing of the quality of life in children with vernal keratoconjunctivitis questionnaire. Am J Ophthalmol. 2007 Oct; 144(4):557-63. PMID: 17693381.
    Citations: 7     Fields:    Translation:Humans
  81. Micera A, Lambiase A, Stampachiacchiere B, Sgrulletta R, Normando EM, Bonini S, Bonini S. Nerve growth factor has a modulatory role on human primary fibroblast cultures derived from vernal keratoconjunctivitis-affected conjunctiva. Mol Vis. 2007 Jun 21; 13:981-7. PMID: 17653039.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  82. Mantelli F, Tiberi E, Micera A, Lambiase A, Visintini F, Bonini S. MUC5AC overexpression in tear film of neonates. Graefes Arch Clin Exp Ophthalmol. 2007 Sep; 245(9):1377-81. PMID: 17541622.
    Citations: 7     Fields:    Translation:Humans
  83. Micera A, Lambiase A, Stampachiacchiere B, Bonini S, Bonini S, Levi-Schaffer F. Nerve growth factor and tissue repair remodeling: trkA(NGFR) and p75(NTR), two receptors one fate. Cytokine Growth Factor Rev. 2007 Jun-Aug; 18(3-4):245-56. PMID: 17531524.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  84. Lambiase A, Coassin M, Costa N, Lauretti P, Micera A, Ghinelli E, Aloe L, Rama P, Bonini S. Topical treatment with nerve growth factor in an animal model of herpetic keratitis. Graefes Arch Clin Exp Ophthalmol. 2008 Jan; 246(1):121-7. PMID: 17479276.
    Citations: 4     Fields:    Translation:AnimalsCells
  85. Lambiase A, Coassin M, Sposato V, Micera A, Sacchetti M, Bonini S, Aloe L. NGF topical application in patients with corneal ulcer does not generate circulating NGF antibodies. Pharmacol Res. 2007 Jul; 56(1):65-9. PMID: 17512750.
    Citations: 4     Fields:    Translation:HumansAnimalsCTClinical Trials
  86. Bonini S, Mantelli F, Moretti C, Lambiase A, Bonini S, Micera A. Itchy-dry eye associated with polycystic ovary syndrome. Am J Ophthalmol. 2007 May; 143(5):763-771. PMID: 17362862.
    Citations: 5     Fields:    Translation:HumansCells
  87. Sgrulletta R, Lambiase A, Micera A, Bonini S. Corneal ulcer as an atypical presentation of ocular cicatricial pemphigoid. Eur J Ophthalmol. 2007 Jan-Feb; 17(1):121-3. PMID: 17294392.
    Citations: 1     Fields:    Translation:Humans
  88. Micera A, Bonini S, Lambiase A, Lapucci G, Bonini S, Rasi G. Conjunctival expression of thymosin-beta4 in vernal keratoconjunctivitis. Mol Vis. 2006 Dec 20; 12:1594-600. PMID: 17200658.
    Citations: 1     Fields:    Translation:HumansCells
  89. Mantelli F, Moretti C, Micera A, Bonini S. Conjunctival mucin deficiency in complete androgen insensitivity syndrome (CAIS). Graefes Arch Clin Exp Ophthalmol. 2007 Jun; 245(6):899-902. PMID: 17120009.
    Citations: 8     Fields:    Translation:Humans
  90. Lambiase A, Pagani L, Di Fausto V, Sposato V, Coassin M, Bonini S, Aloe L. Nerve growth factor eye drop administrated on the ocular surface of rodents affects the nucleus basalis and septum: biochemical and structural evidence. Brain Res. 2007 Jan 05; 1127(1):45-51. PMID: 17113055.
    Citations: 5     Fields:    Translation:AnimalsCells
  91. Sacchetti M, Lambiase A, Aronni S, Griggi T, Ribatti V, Bonini S, Bonini S. Hyperosmolar conjunctival provocation for the evaluation of nonspecific hyperreactivity in healthy patients and patients with allergy. J Allergy Clin Immunol. 2006 Oct; 118(4):872-7. PMID: 17030240.
    Citations: 2     Fields:    Translation:Humans
  92. Micera A, Lambiase A, Puxeddu I, Aloe L, Stampachiacchiere B, Levi-Schaffer F, Bonini S, Bonini S. Nerve growth factor effect on human primary fibroblastic-keratocytes: possible mechanism during corneal healing. Exp Eye Res. 2006 Oct; 83(4):747-57. PMID: 16716299.
    Citations: 20     Fields:    Translation:HumansCells
  93. Gulati A, Sacchetti M, Bonini S, Dana R. Chemokine receptor CCR5 expression in conjunctival epithelium of patients with dry eye syndrome. Arch Ophthalmol. 2006 May; 124(5):710-6. PMID: 16682594.
    Citations: 16     Fields:    Translation:HumansCells
  94. Lambiase A, Merlo D, Mollinari C, Bonini P, Rinaldi AM, D' Amato M, Micera A, Coassin M, Rama P, Bonini S, Garaci E. Molecular basis for keratoconus: lack of TrkA expression and its transcriptional repression by Sp3. Proc Natl Acad Sci U S A. 2005 Nov 15; 102(46):16795-800. PMID: 16275928.
    Citations: 13     Fields:    Translation:HumansCells
  95. Lambiase A, Tirassa P, Micera A, Aloe L, Bonini S. Pharmacokinetics of conjunctivally applied nerve growth factor in the retina and optic nerve of adult rats. Invest Ophthalmol Vis Sci. 2005 Oct; 46(10):3800-6. PMID: 16186366.
    Citations: 12     Fields:    Translation:Animals
  96. Coassin M, Lambiase A, Micera A, Tirassa P, Aloe L, Bonini S. Nerve growth factor modulates in vitro the expression and release of TGF-beta1 by amniotic membrane. Graefes Arch Clin Exp Ophthalmol. 2006 Apr; 244(4):485-91. PMID: 16158307.
    Citations: 3     Fields:    Translation:Humans
  97. Bonini S, Micera A, Iovieno A, Lambiase A, Bonini S. Expression of Toll-like receptors in healthy and allergic conjunctiva. Ophthalmology. 2005 Sep; 112(9):1528; discussion 1548-9. PMID: 16023216.
    Citations: 24     Fields:    Translation:HumansCells
  98. Bonini S. Ocular allergies in 2005. Expert Rev Clin Immunol. 2005 Jul; 1(2):179-81. PMID: 20476930.
    Citations:    Fields:    
  99. Lenzi L, Coassin M, Lambiase A, Bonini S, Amendola T, Aloe L. Effect of exogenous administration of nerve growth factor in the retina of rats with inherited retinitis pigmentosa. Vision Res. 2005 Jun; 45(12):1491-500. PMID: 15781068.
    Citations: 19     Fields:    Translation:AnimalsCells
  100. Cortes M, Lambiase A, Sacchetti M, Aronni S, Bonini S. Limbal stem cell deficiency associated with LADD syndrome. Arch Ophthalmol. 2005 May; 123(5):691-4. PMID: 15883293.
    Citations: 2     Fields:    Translation:HumansCells
  101. Tonini G, Vincenzi B, Santini D, Olzi D, Lambiase A, Bonini S. Ocular toxicity related to cetuximab monotherapy in an advanced colorectal cancer patient. J Natl Cancer Inst. 2005 Apr 20; 97(8):606-7. PMID: 15840884.
    Citations: 2     Fields:    Translation:Humans
  102. Sacchetti M, Lambiase A, Cortes M, Sgrulletta R, Bonini S, Merlo D, Bonini S. Clinical and cytological findings in limbal stem cell deficiency. Graefes Arch Clin Exp Ophthalmol. 2005 Sep; 243(9):870-6. PMID: 15778841.
    Citations: 14     Fields:    Translation:HumansCells
  103. Coassin M, Lambiase A, Costa N, De Gregorio A, Sgrulletta R, Sacchetti M, Aloe L, Bonini S. Efficacy of topical nerve growth factor treatment in dogs affected by dry eye. Graefes Arch Clin Exp Ophthalmol. 2005 Feb; 243(2):151-5. PMID: 15650854.
    Citations: 14     Fields:    Translation:AnimalsCells
  104. Micera A, Lambiase A, Aloe L, Bonini S, Levi-Schaffer F, Bonini S. Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseases. Cytokine Growth Factor Rev. 2004 Dec; 15(6):411-7. PMID: 15561599.
    Citations: 17     Fields:    Translation:Humans
  105. Lambiase A, Micera A, Sgrulletta R, Bonini S, Bonini S. Nerve growth factor and the immune system: old and new concepts in the cross-talk between immune and resident cells during pathophysiological conditions. Curr Opin Allergy Clin Immunol. 2004 Oct; 4(5):425-30. PMID: 15349043.
    Citations: 8     Fields:    Translation:Humans
  106. Manni G, Centofanti M, Sacchetti M, Oddone F, Bonini S, Parravano M, Bucci MG. Demographic and clinical factors associated with development of brimonidine tartrate 0.2%-induced ocular allergy. J Glaucoma. 2004 Apr; 13(2):163-7. PMID: 15097264.
    Citations: 3     Fields:    Translation:Humans
  107. Landi F, Aloe L, Russo A, Cesari M, Onder G, Bonini S, Carbonin PU, Bernabei R. Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial. Ann Intern Med. 2003 Oct 21; 139(8):635-41. PMID: 14568851.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  108. Bonini S, Lambiase A, Sgrulletta R, Bonini S. Allergic chronic inflammation of the ocular surface in vernal keratoconjunctivitis. Curr Opin Allergy Clin Immunol. 2003 Oct; 3(5):381-7. PMID: 14501439.
    Citations: 10     Fields:    Translation:Humans
  109. Ghinelli E, Aloe L, Cortes M, Micera A, Lambiase A, Bonini S. Nerve growth factor (NGF) and lenses: effects of NGF in an in vitro rat model of cataract. Graefes Arch Clin Exp Ophthalmol. 2003 Oct; 241(10):845-51. PMID: 13680251.
    Citations: 1     Fields:    Translation:Animals
  110. Trocme SD, Leiferman KM, George T, Bonini S, Foster CS, Smit EE, Sra SK, Grabowski LR, Dohlman CH. Neutrophil and eosinophil participation in atopic and vernal keratoconjunctivitis. Curr Eye Res. 2003 Jun; 26(6):319-25. PMID: 12868012.
    Citations: 5     Fields:    Translation:HumansCells
  111. Lambiase A, Bonini S, Rasi G, Coassin M, Bruscolini A, Bonini S. Montelukast, a leukotriene receptor antagonist, in vernal keratoconjunctivitis associated with asthma. Arch Ophthalmol. 2003 May; 121(5):615-20. PMID: 12742837.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  112. D'Angelo G, Lambiase A, Cortes M, Sgrulletta R, Pasqualetti R, Lamagna A, Bonini S. Preservative-free diclofenac sodium 0.1% for vernal keratoconjunctivitis. Graefes Arch Clin Exp Ophthalmol. 2003 Mar; 241(3):192-5. PMID: 12644942.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  113. Bonini S, Lambiase A, Sacchetti M, Bonini S. Cytokines in ocular allergy. Int Ophthalmol Clin. 2003; 43(1):27-32. PMID: 12544392.
    Citations: 3     Fields:    Translation:Humans
  114. Accorinti M, Bruscolini A, Lambiase A, Speranza S, Bonini S, Pivetti-Pezzi P. Nerve growth factor in Behçet's disease. Adv Exp Med Biol. 2003; 528:283-5. PMID: 12918708.
    Citations:    Fields:    Translation:Humans
  115. Lambiase A, Bonini S, Manni L, Ghinelli E, Tirassa P, Rama P, Aloe L. Intraocular production and release of nerve growth factor after iridectomy. Invest Ophthalmol Vis Sci. 2002 Jul; 43(7):2334-40. PMID: 12091435.
    Citations: 7     Fields:    Translation:Animals
  116. Bonini S, Aloe L, Bonini S, Rama P, Lamagna A, Lambiase A. Nerve growth factor (NGF): an important molecule for trophism and healing of the ocular surface. Adv Exp Med Biol. 2002; 506(Pt A):531-7. PMID: 12613957.
    Citations: 6     Fields:    Translation:HumansAnimals
  117. Bielory L, Bonini S, Bonini S. Allergic eye disorders. Clin Allergy Immunol. 2002; 16:311-23. PMID: 11577546.
    Citations: 1     Fields:    Translation:Humans
  118. Trocmé SD, Bonini S, Barney NP, Bloch KJ, Allansmith MR. Effects of topical pre-treatment with dexamethasone on the immediate and late phases of topically induced ocular anaphylaxis in the rat. Acta Ophthalmol (Copenh). 1988 Feb; 66(1):24-32. PMID: 3364167.
    Citations:    Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.