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George Richard Washko, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL122464 (WASHKO, GEORGE R) Dec 1, 2014 - Nov 30, 2018
    NIH/NHLBI
    Skeletal muscle, subcutaneous fat, and clinical outcomes in smokers
    Role: Principal Investigator
  2. R01HL116473 (WASHKO, GEORGE R) Feb 1, 2013 - Jun 30, 2022
    NIH/NHLBI
    The clinical impact of pulmonary vascular remodeling in smokers
    Role: Co-Principal Investigator
  3. R01HL107246 (WASHKO, GEORGE R) Feb 7, 2011 - Jan 31, 2015
    NIH/NHLBI
    Computed Tomographic characterization of subjects enrolled in the STATCOPE trial
    Role: Principal Investigator
  4. R03HL097005 (CHOI, AUGUSTINE M) May 1, 2009 - Apr 30, 2011
    NIH/NHLBI
    Autophagy in COPD
    Role: Co-Principal Investigator
  5. K23HL089353 (WASHKO, GEORGE R) Aug 1, 2008 - Jun 30, 2013
    NIH/NHLBI
    Using Computed Tomographic Imaging as a biomarker for Clinical COPD Research
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Rahaghi FN, Winkler T, Kohli P, Nardelli P, Martí-Fuster B, Ross JC, Radhakrishnan R, Blackwater T, Ash SY, de La Bruere I, Diaz AA, Channick RN, Harris RS, Washko GR, San José Estépar R. Quantification of the Pulmonary Vascular Response to Inhaled Nitric Oxide Using Noncontrast Computed Tomography Imaging. Circ Cardiovasc Imaging. 2019 Dec; 12(1):e008338. PMID: 30632391.
    Citations:    Fields:    
  2. Washko GR, Nardelli P, Ash SY, Vegas Sanchez-Ferrero G, Rahaghi FN, Come CE, Dransfield MT, Kalhan R, Han MK, Bhatt S, Wells JM, Aaron CP, Diaz AA, Ross JC, Cuttica MJ, Labaki WW, Querejeta Roca G, Shah AM, Young K, Kinney GL, Hokanson JE, Agusti A, San José Estépar R. Arterial Vascular Pruning, Right Ventricular Size and Clinical Outcomes in COPD. Am J Respir Crit Care Med. 2019 Feb 13. PMID: 30758975.
    Citations:    
  3. Synn AJ, Zhang C, Washko GR, San José Estépar R, O'Connor GT, Li W, Mittleman MA, Rice MB. Cigarette Smoke Exposure and Radiographic Pulmonary Vascular Morphology in the Framingham Heart Study. Ann Am Thorac Soc. 2019 Feb 04. PMID: 30714821.
    Citations:    
  4. Putman RK, Gudmundsson G, Axelsson GT, Hida T, Honda O, Araki T, Yanagawa M, Nishino M, Miller ER, Eiriksdottir G, Gudmundsson EF, Tomiyama N, Honda H, Rosas IO, Washko GR, Cho MH, Schwartz DA, Gudnason V, Hatabu H, Hunninghake GM. Imaging Patterns are Associated with Interstitial Lung Abnormality Progression and Mortality. Am J Respir Crit Care Med. 2019 Jan 23. PMID: 30673508.
    Citations:    Fields:    
  5. Rice MB, Li W, Wilker EH, Gold DR, Schwartz J, Zanobetti A, Koutrakis P, Kloog I, Washko GR, O'Connor GT, Mittleman MA. Association of outdoor temperature with lung function in a temperate climate. Eur Respir J. 2019 Jan; 53(1). PMID: 30578386.
    Citations:    Fields:    
  6. Miller ER, Putman RK, Diaz AA, Xu H, San José Estépar R, Araki T, Nishino M, Poli de Frías S, Hida T, Ross J, Coxson H, Dupuis J, O'Connor GT, Silverman EK, Rosas IO, Hatabu H, Washko G, Hunninghake GM. Increased Airway Wall Thickness in Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. Ann Am Thorac Soc. 2018 Dec 13. PMID: 30543456.
    Citations:    Fields:    
  7. Washko GR. POINT: Should Chest CT Be Part of Routine Clinical Care for COPD? Yes. Chest. 2018 Dec; 154(6):1276-1278. PMID: 30526966.
    Citations:    Fields:    
  8. Washko GR. Rebuttal From Dr Washko. Chest. 2018 Dec; 154(6):1281-1282. PMID: 30526968.
    Citations:    Fields:    
  9. Washko GR, Parraga G. COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging. Eur Respir J. 2018 Nov; 52(5). PMID: 30337445.
    Citations:    Fields:    
  10. Diaz AA, Maselli DJ, Rahaghi F, Come CE, Yen A, Maclean ES, Okajima Y, Martinez CH, Yamashiro T, Lynch DA, Wang W, Kinney GL, Washko GR, San José Estépar R. Pulmonary vascular pruning in smokers with bronchiectasis. ERJ Open Res. 2018 Oct; 4(4). PMID: 30480001.
    Citations:    
  11. Ross JC, Castaldi PJ, Cho MH, Hersh CP, Rahaghi FN, Sánchez-Ferrero GV, Parker MM, Litonjua AA, Sparrow D, Dy JG, Silverman EK, Washko GR, San José Estépar R. Longitudinal Modeling of Lung Function Trajectories in Smokers with and without Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 Oct 15; 198(8):1033-1042. PMID: 29671603.
    Citations: 1     Fields:    
  12. González G, Ash SY, San José Estépar R, Washko G. Reply to Mummadi et al.: Overfitting and Use of Mismatched Cohorts in Deep Learning Models: Preventable Design Limitations. Am J Respir Crit Care Med. 2018 Aug 15; 198(4):545. PMID: 29641211.
    Citations:    Fields:    
  13. Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR. Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort. Am J Respir Crit Care Med. 2018 Jul 01; 198(1):39-50. PMID: 29672122.
    Citations:    Fields:    
  14. Ash SY, Harmouche R, Ross JC, Diaz AA, Rahaghi FN, Vegas Sanchez-Ferrero G, Putman RK, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Bowler RP, Lynch DA, Hatabu H, Bhatt SP, Dransfield MT, Wells JM, Rosas IO, San Jose Estepar R, Washko GR. Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort. Radiology. 2018 08; 288(2):600-609. PMID: 29869957.
    Citations:    Fields:    Translation:Humans
  15. Morrow JD, Glass K, Cho MH, Hersh CP, Pinto-Plata V, Celli B, Marchetti N, Criner G, Bueno R, Washko G, Choi AMK, Quackenbush J, Silverman EK, DeMeo DL. Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci. Am J Respir Crit Care Med. 2018 May 15; 197(10):1275-1284. PMID: 29313708.
    Citations:    Fields:    
  16. Diaz AA, Martinez CH, Harmouche R, Young TP, McDonald ML, Ross JC, Han ML, Bowler R, Make B, Regan EA, Silverman EK, Crapo J, Boriek AM, Kinney GL, Hokanson JE, Estepar RSJ, Washko GR. Pectoralis muscle area and mortality in smokers without airflow obstruction. Respir Res. 2018 04 10; 19(1):62. PMID: 29636050.
    Citations:    Fields:    Translation:Humans
  17. Miller ER, Putman RK, Vivero M, Hung Y, Araki T, Nishino M, Washko GR, Rosas IO, Hatabu H, Sholl LM, Hunninghake GM. Histopathology of Interstitial Lung Abnormalities in the Context of Lung Nodule Resections. Am J Respir Crit Care Med. 2018 Apr 01; 197(7):955-958. PMID: 28934558.
    Citations:    Fields:    
  18. Onieva JO, Serrano GG, Young TP, Washko GR, Carbayo MJL, Estépar RSJ. Multiorgan structures detection using deep convolutional neural networks. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10574. PMID: 30122800.
    Citations:    
  19. Ash SY, Harmouche R, Putman RK, Ross JC, Martinez FJ, Choi AM, Bowler RP, Regan EA, Curtis JL, Han MK, Boucher RC, O'Neal WK, Hatabu H, Lynch DA, Rosas IO, Hunninghake GM, San Jose Estepar R, Washko GR. Association between acute respiratory disease events and the MUC5B promoter polymorphism in smokers. Thorax. 2018 11; 73(11):1071-1074. PMID: 29440587.
    Citations:    Fields:    
  20. Washko GR. Susceptibility to Inhalational Lung Injury: We Need More Than the FEV1. Ann Am Thorac Soc. 2018 02; 15(2):156-157. PMID: 29388819.
    Citations:    Fields:    Translation:HumansCells
  21. Morrow JD, Cho MH, Platig J, Zhou X, DeMeo DL, Qiu W, Celli B, Marchetti N, Criner GJ, Bueno R, Washko GR, Glass K, Quackenbush J, Silverman EK, Hersh CP. Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease. Hum Genomics. 2018 01 15; 12(1):1. PMID: 29335020.
    Citations:    Fields:    Translation:Humans
  22. Vegas-Sánchez-Ferrero G, Ledesma-Carbayo MJ, Washko GR, Estépar RSJ. Autocalibration method for non-stationary CT bias correction. Med Image Anal. 2018 02; 44:115-125. PMID: 29247875.
    Citations:    Fields:    
  23. Diaz AA, Strand M, Coxson HO, Ross JC, San Jose Estepar R, Lynch D, van Rikxoort EM, Rosas IO, Hunninghake GM, Putman RK, Hatabu H, Yen A, Kinney GL, Hokanson JE, Silverman EK, Crapo J, Washko GR. Disease Severity Dependence of the Longitudinal Association Between CT Lung Density and Lung Function in Smokers. Chest. 2018 Mar; 153(3):638-645. PMID: 29066389.
    Citations: 2     Fields:    
  24. Washko GR, Coxson HO, O'Donnell DE, Aaron SD. CT imaging of chronic obstructive pulmonary disease: insights, disappointments, and promise. Lancet Respir Med. 2017 11; 5(11):903-908. PMID: 28965820.
    Citations:    Fields:    Translation:Humans
  25. Boueiz A, Chang Y, Cho MH, Washko GR, San José Estépar R, Bowler RP, Crapo JD, DeMeo DL, Dy JG, Silverman EK, Castaldi PJ. Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression. Chest. 2018 Jan; 153(1):65-76. PMID: 28943279.
    Citations:    Fields:    
  26. Putman RK, Gudmundsson G, Araki T, Nishino M, Sigurdsson S, Gudmundsson EF, Eiríksdottír G, Aspelund T, Ross JC, San José Estépar R, Miller ER, Yamada Y, Yanagawa M, Tomiyama N, Launer LJ, Harris TB, El-Chemaly S, Raby BA, Cho MH, Rosas IO, Washko GR, Schwartz DA, Silverman EK, Gudnason V, Hatabu H, Hunninghake GM. The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes. Eur Respir J. 2017 09; 50(3). PMID: 28893869.
    Citations:    Fields:    Translation:HumansCells
  27. Diaz AA, Rahaghi FN, Doyle TJ, Young TP, Maclean ES, Martinez CH, San José Estépar R, Guerra S, Tesfaigzi Y, Rosas IO, Washko GR, Wilson DO. Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study. Chronic Obstr Pulm Dis. 2017 Sep 05; 4(4):297-304. PMID: 29354674.
    Citations:    
  28. Vegas-Sánchez-Ferrero G, Ledesma-Carbayo MJ, Washko GR, San José Estépar R. Statistical characterization of noise for spatial standardization of CT scans: Enabling comparison with multiple kernels and doses. Med Image Anal. 2017 Aug; 40:44-59. PMID: 28622587.
    Citations: 1     Fields:    Translation:Humans
  29. Ash SY, Harmouche R, Putman RK, Ross JC, Diaz AA, Hunninghake GM, Onieva Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, San Jose Estepar R, Washko GR. Clinical and Genetic Associations of Objectively Identified Interstitial Changes in Smokers. Chest. 2017 10; 152(4):780-791. PMID: 28506611.
    Citations: 2     Fields:    Translation:HumansCells
  30. Araki T, Yanagawa M, Sun FJ, Dupuis J, Nishino M, Yamada Y, Washko GR, Christiani DC, Tomiyama N, O'Connor GT, Hunninghake GM, Hatabu H. Pleural abnormalities in the Framingham Heart Study: prevalence and CT image features. Occup Environ Med. 2017 10; 74(10):756-761. PMID: 28468931.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  31. Boueiz A, Lutz SM, Cho MH, Hersh CP, Bowler RP, Washko GR, Halper-Stromberg E, Bakke P, Gulsvik A, Laird NM, Beaty TH, Coxson HO, Crapo JD, Silverman EK, Castaldi PJ, DeMeo DL. Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution. Am J Respir Crit Care Med. 2017 03 15; 195(6):757-771. PMID: 27669027.
    Citations: 4     Fields:    Translation:Humans
  32. Morrow JD, Zhou X, Lao T, Jiang Z, DeMeo DL, Cho MH, Qiu W, Cloonan S, Pinto-Plata V, Celli B, Marchetti N, Criner GJ, Bueno R, Washko GR, Glass K, Quackenbush J, Choi AM, Silverman EK, Hersh CP. Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue. Sci Rep. 2017 03 13; 7:44232. PMID: 28287180.
    Citations: 7     Fields:    Translation:HumansAnimalsCTClinical Trials
  33. Ash SY, Harmouche R, Vallejo DL, Villalba JA, Ostridge K, Gunville R, Come CE, Onieva Onieva J, Ross JC, Hunninghake GM, El-Chemaly SY, Doyle TJ, Nardelli P, Sanchez-Ferrero GV, Goldberg HJ, Rosas IO, San Jose Estepar R, Washko GR. Densitometric and local histogram based analysis of computed tomography images in patients with idiopathic pulmonary fibrosis. Respir Res. 2017 03 07; 18(1):45. PMID: 28264721.
    Citations: 4     Fields:    Translation:Humans
  34. Rahaghi FN, Vegas-Sanchez-Ferrero G, Minhas JK, Come CE, De La Bruere I, Wells JM, González G, Bhatt SP, Fenster BE, Diaz AA, Kohli P, Ross JC, Lynch DA, Dransfield MT, Bowler RP, Ledesma-Carbayo MJ, San José Estépar R, Washko GR. Ventricular Geometry From Non-contrast Non-ECG-gated CT Scans: An Imaging Marker of Cardiopulmonary Disease in Smokers. Acad Radiol. 2017 May; 24(5):594-602. PMID: 28215632.
    Citations: 4     Fields:    Translation:Humans
  35. Ash SY, Washko GR. Interstitial lung abnormalities: risk and opportunity. Lancet Respir Med. 2017 02; 5(2):95-96. PMID: 28145231.
    Citations:    Fields:    Translation:Humans
  36. Araki T, Putman RK, Hatabu H, Gao W, Dupuis J, Latourelle JC, Nishino M, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Schwartz DA, Rosas IO, Washko GR, O'Connor GT, Hunninghake GM. Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study. Am J Respir Crit Care Med. 2016 12 15; 194(12):1514-1522. PMID: 27314401.
    Citations: 20     Fields:    Translation:Humans
  37. Ash SY, Harmouche R, Ross JC, Diaz AA, Hunninghake GM, Putman RK, Onieva J, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Rosas IO, Estepar RSJ, Washko GR. The Objective Identification and Quantification of Interstitial Lung Abnormalities in Smokers. Acad Radiol. 2017 08; 24(8):941-946. PMID: 27989445.
    Citations: 4     Fields:    Translation:Humans
  38. Washko GR, Kinney GL, Ross JC, San José Estépar R, Han MK, Dransfield MT, Kim V, Hatabu H, Come CE, Bowler RP, Silverman EK, Crapo J, Lynch DA, Hokanson J, Diaz AA. Lung Mass in Smokers. Acad Radiol. 2017 04; 24(4):386-392. PMID: 27940230.
    Citations: 2     Fields:    Translation:Humans
  39. Diaz AA, Young TP, Maselli DJ, Martinez CH, Gill R, Nardelli P, Wang W, Kinney GL, Hokanson JE, Washko GR, San Jose Estepar R. Quantitative CT Measures of Bronchiectasis in Smokers. Chest. 2017 06; 151(6):1255-1262. PMID: 27890712.
    Citations: 3     Fields:    Translation:Humans
  40. Rahaghi FN, Wells JM, Come CE, De La Bruere IA, Bhatt SP, Ross JC, Vegas-Sánchez-Ferrero G, Diaz AA, Minhas J, Dransfield MT, San José Estépar R, Washko GR. Arterial and Venous Pulmonary Vascular Morphology and Their Relationship to Findings in Cardiac Magnetic Resonance Imaging in Smokers. J Comput Assist Tomogr. 2016 Nov/Dec; 40(6):948-952. PMID: 27636250.
    Citations: 2     Fields:    Translation:Humans
  41. Morrow JD, Cho MH, Hersh CP, Pinto-Plata V, Celli B, Marchetti N, Criner G, Bueno R, Washko G, Glass K, Choi AM, Quackenbush J, Silverman EK, DeMeo DL. DNA methylation profiling in human lung tissue identifies genes associated with COPD. Epigenetics. 2016 Aug 26; 1-10. PMID: 27564456.
    Citations: 6     Fields:    
  42. Diaz AA, Young TP, Maselli DJ, Martinez CH, Maclean ES, Yen A, Dass C, Simpson SA, Lynch DA, Kinney GL, Hokanson JE, Washko GR, San José Estépar R. Bronchoarterial ratio in never-smokers adults: Implications for bronchial dilation definition. Respirology. 2017 01; 22(1):108-113. PMID: 27538197.
    Citations: 1     Fields:    Translation:Humans
  43. Ho JE, Gao W, Levy D, Santhanakrishnan R, Araki T, Rosas IO, Hatabu H, Latourelle JC, Nishino M, Dupuis J, Washko GR, O'Connor GT, Hunninghake GM. Galectin-3 Is Associated with Restrictive Lung Disease and Interstitial Lung Abnormalities. Am J Respir Crit Care Med. 2016 07 01; 194(1):77-83. PMID: 26771117.
    Citations: 8     Fields:    Translation:Humans
  44. González G, Washko GR, Estépar RS. AUTOMATED AGATSTON SCORE COMPUTATION IN A LARGE DATASET OF NON ECG-GATED CHEST COMPUTED TOMOGRAPHY. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:53-57. PMID: 27974951.
    Citations: 2     
  45. Vegas-Sanchez-Ferrero G, Washko G, Rahaghi FN, Ledesma-Carbayo MJ, Estépar RS. DERIVATION OF A TEST STATISTIC FOR EMPHYSEMA QUANTIFICATION. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:1269-1273. PMID: 27974952.
    Citations:    
  46. Lai PS, Hang JQ, Zhang FY, Sun J, Zheng BY, Su L, Washko GR, Christiani DC. Imaging Phenotype of Occupational Endotoxin-Related Lung Function Decline. Environ Health Perspect. 2016 09; 124(9):1436-42. PMID: 27138294; PMCID: PMC5010398.
    Citations:    Fields:    Translation:HumansPHPublic Health
  47. Harmouche R, Ross JC, Diaz AA, Washko GR, Estepar RS. A Robust Emphysema Severity Measure Based on Disease Subtypes. Acad Radiol. 2016 Apr; 23(4):421-8. PMID: 26947221.
    Citations:    Fields:    Translation:Humans
  48. Rahaghi FN, Ross JC, Agarwal M, González G, Come CE, Diaz AA, Vegas-Sánchez-Ferrero G, Hunsaker A, San José Estépar R, Waxman AB, Washko GR. Pulmonary vascular morphology as an imaging biomarker in chronic thromboembolic pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):70-81. PMID: 27162616.
    Citations: 3     
  49. Washko GR, Parraga G. Imaging Biomarkers in Lymphangioleiomyomatosis Clinical Trials. A Wolf in Sheep's Clothing? Ann Am Thorac Soc. 2016 Mar; 13(3):307-8. PMID: 26963351.
    Citations:    Fields:    Translation:HumansAnimals
  50. Putman RK, Hatabu H, Araki T, Gudmundsson G, Gao W, Nishino M, Okajima Y, Dupuis J, Latourelle JC, Cho MH, El-Chemaly S, Coxson HO, Celli BR, Fernandez IE, Zazueta OE, Ross JC, Harmouche R, Estépar RS, Diaz AA, Sigurdsson S, Gudmundsson EF, Eiríksdottír G, Aspelund T, Budoff MJ, Kinney GL, Hokanson JE, Williams MC, Murchison JT, MacNee W, Hoffmann U, O'Donnell CJ, Launer LJ, Harrris TB, Gudnason V, Silverman EK, O'Connor GT, Washko GR, Rosas IO, Hunninghake GM. Association Between Interstitial Lung Abnormalities and All-Cause Mortality. JAMA. 2016 Feb 16; 315(7):672-81. PMID: 26881370.
    Citations: 30     Fields:    Translation:Humans
  51. Hardin M, Foreman M, Dransfield MT, Hansel N, Han MK, Cho MH, Bhatt SP, Ramsdell J, Lynch D, Curtis JL, Silverman EK, Washko G, DeMeo D. Sex-specific features of emphysema among current and former smokers with COPD. Eur Respir J. 2016 Jan; 47(1):104-12. PMID: 26541532.
    Citations: 2     Fields:    Translation:Humans
  52. Kliment CR, Araki T, Doyle TJ, Gao W, Dupuis J, Latourelle JC, Zazueta OE, Fernandez IE, Nishino M, Okajima Y, Ross JC, Estépar RS, Diaz AA, Lederer DJ, Schwartz DA, Silverman EK, Rosas IO, Washko GR, O'Connor GT, Hatabu H, Hunninghake GM. A comparison of visual and quantitative methods to identify interstitial lung abnormalities. BMC Pulm Med. 2015 Oct 29; 15:134. PMID: 26514822.
    Citations: 6     Fields:    Translation:HumansCells
  53. Araki T, Nishino M, Gao W, Dupuis J, Putman RK, Washko GR, Hunninghake GM, O'Connor GT, Hatabu H. Pulmonary cysts identified on chest CT: are they part of aging change or of clinical significance? Thorax. 2015 Dec; 70(12):1156-62. PMID: 26514407; PMCID: PMC4848007.
    Citations: 2     Fields:    Translation:Humans
  54. Kurugol S, Come CE, Diaz AA, Ross JC, Kinney GL, Black-Shinn JL, Hokanson JE, Budoff MJ, Washko GR, San Jose Estepar R. Automated quantitative 3D analysis of aorta size, morphology, and mural calcification distributions. Med Phys. 2015 Sep; 42(9):5467-78. PMID: 26328995.
    Citations: 2     Fields:    Translation:Humans
  55. Bhatt SP, Wells JM, Kinney GL, Washko GR, Budoff M, Kim YI, Bailey WC, Nath H, Hokanson JE, Silverman EK, Crapo J, Dransfield MT. ß-Blockers are associated with a reduction in COPD exacerbations. Thorax. 2016 Jan; 71(1):8-14. PMID: 26283710.
    Citations: 12     Fields:    Translation:Humans
  56. Come CE, Washko GR. CT Scanning in COPD - Is it Time to Move On? Chronic Obstr Pulm Dis. 2015 Jul 14; 2(3):201-203. PMID: 28848843.
    Citations:    
  57. Washko GR. Chest computed tomography for phenotying chronic obstructive pulmonary disease. A pathway and a challenge for personalized medicine. Ann Am Thorac Soc. 2015 Jul; 12(7):966-7. PMID: 26203604.
    Citations:    Fields:    Translation:Humans
  58. Doyle TJ, Patel AS, Hatabu H, Nishino M, Wu G, Osorio JC, Golzarri MF, Traslosheros A, Chu SG, Frits ML, Iannaccone CK, Koontz D, Fuhrman C, Weinblatt ME, El-Chemaly SY, Washko GR, Hunninghake GM, Choi AM, Dellaripa PF, Oddis CV, Shadick NA, Ascherman DP, Rosas IO. Detection of Rheumatoid Arthritis-Interstitial Lung Disease Is Enhanced by Serum Biomarkers. Am J Respir Crit Care Med. 2015 Jun 15; 191(12):1403-12. PMID: 25822095; PMCID: PMC4476561.
    Citations: 13     Fields:    Translation:Humans
  59. Araki T, Nishino M, Gao W, Dupuis J, Hunninghake GM, Murakami T, Washko GR, O'Connor GT, Hatabu H. Normal thymus in adults: appearance on CT and associations with age, sex, BMI and smoking. Eur Radiol. 2016 Jan; 26(1):15-24. PMID: 25925358; PMCID: PMC4847950.
    Citations: 3     Fields:    Translation:Humans
  60. Wells JM, Iyer AS, Rahaghi FN, Bhatt SP, Gupta H, Denney TS, Lloyd SG, Dell'Italia LJ, Nath H, Estepar RS, Washko GR, Dransfield MT. Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary disease. Circ Cardiovasc Imaging. 2015 Apr; 8(4). PMID: 25855668.
    Citations: 16     Fields:    Translation:Humans
  61. Washko GR. Imaging to predict therapeutic outcomes. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):724-5. PMID: 25830515.
    Citations: 1     Fields:    Translation:Humans
  62. Araki T, Nishino M, Zazueta OE, Gao W, Dupuis J, Okajima Y, Latourelle JC, Rosas IO, Murakami T, O'Connor GT, Washko GR, Hunninghake GM, Hatabu H. Paraseptal emphysema: Prevalence and distribution on CT and association with interstitial lung abnormalities. Eur J Radiol. 2015 Jul; 84(7):1413-8. PMID: 25868675; PMCID: PMC4450117.
    Citations: 7     Fields:    Translation:Humans
  63. Rice MB, Ljungman PL, Wilker EH, Dorans KS, Gold DR, Schwartz J, Koutrakis P, Washko GR, O'Connor GT, Mittleman MA. Long-term exposure to traffic emissions and fine particulate matter and lung function decline in the Framingham heart study. Am J Respir Crit Care Med. 2015 Mar 15; 191(6):656-64. PMID: 25590631; PMCID: PMC4384780.
    Citations: 26     Fields:    Translation:HumansPHPublic Health
  64. DuBrock HM, Bankier AA, Silva M, Litmanovich DE, Curry MP, Washko GR. Pulmonary Vessel Cross-sectional Area before and after Liver Transplantation: Quantification with Computed Tomography. Acad Radiol. 2015 Jun; 22(6):752-9. PMID: 25770631.
    Citations:    Fields:    Translation:Humans
  65. Chupp GL, Washko GR. The promise and peril of functional genomics in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015 Mar 01; 191(5):497-9. PMID: 25723821.
    Citations:    Fields:    Translation:Humans
  66. Araki T, Nishino M, Gao W, Dupuis J, Washko GR, Hunninghake GM, Murakami T, O'Connor GT, Hatabu H. Anterior Mediastinal Masses in the Framingham Heart Study: Prevalence and CT Image Characteristics. Eur J Radiol Open. 2015; 2:26-31. PMID: 25705709.
    Citations: 3     
  67. Diaz AA, Young TP, Kurugol S, Eckbo E, Muralidhar N, Chapman JK, Kinney GL, Ross JC, San Jose Estepar R, Harmouche R, Black-Shinn JL, Budoff M, Bowler RP, Hokanson J, Washko GR. Abdominal Visceral Adipose Tissue is Associated with Myocardial Infarction in Patients with COPD. Chronic Obstr Pulm Dis. 2015; 2(1):8-16. PMID: 25914898.
    Citations: 6     
  68. Rahaghi FN, Come CE, Ross J, Harmouche R, Diaz AA, Estepar RS, Washko G. Morphologic Response of the Pulmonary Vasculature to Endoscopic Lung Volume Reduction. Chronic Obstr Pulm Dis. 2015; 2(3):214-222. PMID: 26587564.
    Citations: 1     
  69. Diaz AA, Hardin ME, Come CE, San José Estépar R, Ross JC, Kurugol S, Okajima Y, Han MK, Kim V, Ramsdell J, Silverman EK, Crapo JD, Lynch DA, Make B, Barr RG, Hersh CP, Washko GR. Childhood-onset asthma in smokers. association between CT measures of airway size, lung function, and chronic airflow obstruction. Ann Am Thorac Soc. 2014 Nov; 11(9):1371-8. PMID: 25296268; PMCID: PMC4298990.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  70. Bowler RP, Kim V, Regan E, Williams AAA, Santorico SA, Make BJ, Lynch DA, Hokanson JE, Washko GR, Bercz P, Soler X, Marchetti N, Criner GJ, Ramsdell J, Han MK, Demeo D, Anzueto A, Comellas A, Crapo JD, Dransfield M, Wells JM, Hersh CP, MacIntyre N, Martinez F, Nath HP, Niewoehner D, Sciurba F, Sharafkhaneh A, Silverman EK, van Beek EJR, Wilson C, Wendt C, Wise RA. Prediction of acute respiratory disease in current and former smokers with and without COPD. Chest. 2014 Oct; 146(4):941-950. PMID: 24945159.
    Citations: 19     Fields:    Translation:Humans
  71. Bhatt SP, Washko GR, Dransfield MT, Sieren JC, Newell JD, Hoffman EA. Comparison of spirometric thresholds in diagnosing smoking-related airflow obstruction: authors' response. Thorax. 2014 Dec; 69(12):1147-8. PMID: 25205585.
    Citations: 1     Fields:    Translation:Humans
  72. Castaldi PJ, Cho MH, San José Estépar R, McDonald ML, Laird N, Beaty TH, Washko G, Crapo JD, Silverman EK. Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns. Am J Respir Crit Care Med. 2014 Aug 15; 190(4):399-409. PMID: 25006744; PMCID: PMC4214129.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  73. Kim V, Desai P, Newell JD, Make BJ, Washko GR, Silverman EK, Crapo JD, Bhatt SP, Criner GJ. Airway wall thickness is increased in COPD patients with bronchodilator responsiveness. Respir Res. 2014 Aug 08; 15:84. PMID: 25248436.
    Citations: 4     Fields:    Translation:Humans
  74. Mizumura K, Cloonan SM, Nakahira K, Bhashyam AR, Cervo M, Kitada T, Glass K, Owen CA, Mahmood A, Washko GR, Hashimoto S, Ryter SW, Choi AM. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J Clin Invest. 2014 Sep; 124(9):3987-4003. PMID: 25083992; PMCID: PMC4151233.
    Citations: 83     Fields:    Translation:AnimalsCells
  75. Diaz AA, Zhou L, Young TP, McDonald ML, Harmouche R, Ross JC, San Jose Estepar R, Wouters EF, Coxson HO, MacNee W, Rennard S, Maltais F, Kinney GL, Hokanson JE, Washko GR. Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers. Acad Radiol. 2014 Oct; 21(10):1255-61. PMID: 25088837; PMCID: PMC4389286.
    Citations: 7     Fields:    Translation:Humans
  76. Rudyanto RD, Kerkstra S, van Rikxoort EM, Fetita C, Brillet PY, Lefevre C, Xue W, Zhu X, Liang J, Öksüz I, Ünay D, Kadipasaoglu K, Estépar RS, Ross JC, Washko GR, Prieto JC, Hoyos MH, Orkisz M, Meine H, Hüllebrand M, Stöcker C, Mir FL, Naranjo V, Villanueva E, Staring M, Xiao C, Stoel BC, Fabijanska A, Smistad E, Elster AC, Lindseth F, Foruzan AH, Kiros R, Popuri K, Cobzas D, Jimenez-Carretero D, Santos A, Ledesma-Carbayo MJ, Helmberger M, Urschler M, Pienn M, Bosboom DG, Campo A, Prokop M, de Jong PA, Ortiz-de-Solorzano C, Muñoz-Barrutia A, van Ginneken B. Comparing algorithms for automated vessel segmentation in computed tomography scans of the lung: the VESSEL12 study. Med Image Anal. 2014 Oct; 18(7):1217-32. PMID: 25113321.
    Citations: 7     Fields:    Translation:Humans
  77. Doyle TJ, Dellaripa PF, Batra K, Frits ML, Iannaccone CK, Hatabu H, Nishino M, Weinblatt ME, Ascherman DP, Washko GR, Hunninghake GM, Choi AMK, Shadick NA, Rosas IO. Functional impact of a spectrum of interstitial lung abnormalities in rheumatoid arthritis. Chest. 2014 Jul; 146(1):41-50. PMID: 24305643; PMCID: PMC4077411.
    Citations: 14     Fields:    Translation:Humans
  78. Han MK, Tayob N, Murray S, Dransfield MT, Washko G, Scanlon PD, Criner GJ, Casaburi R, Connett J, Lazarus SC, Albert R, Woodruff P, Martinez FJ. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1503-8. PMID: 24779680; PMCID: PMC4226018.
    Citations: 19     Fields:    Translation:Humans
  79. Martinez CH, Okajima Y, Murray S, Washko GR, Martinez FJ, Silverman EK, Lee JH, Regan EA, Crapo JD, Curtis JL, Hatabu H, Han MK. Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort. Respir Res. 2014 Jun 03; 15:62. PMID: 24894541.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  80. Rahaghi FN, Lazea D, Dihya S, San José Estépar R, Bueno R, Sugarbaker D, Frendl G, Washko GR. Preoperative pulmonary vascular morphology and its relationship to postpneumonectomy hemodynamics. Acad Radiol. 2014 Jun; 21(6):704-10. PMID: 24809312; PMCID: PMC4266986.
    Citations:    Fields:    Translation:Humans
  81. Wassermann D, Ross J, Washko G, Wells WM, San Jose-Estepar R. Deformable Registration of Feature-Endowed Point Sets Based on Tensor Fields. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit. 2014 Jun; 2014:2729-2735. PMID: 25473253.
    Citations: 1     
  82. Criner GJ, Connett JE, Aaron SD, Albert RK, Bailey WC, Casaburi R, Cooper JA, Curtis JL, Dransfield MT, Han MK, Make B, Marchetti N, Martinez FJ, Niewoehner DE, Scanlon PD, Sciurba FC, Scharf SM, Sin DD, Voelker H, Washko GR, Woodruff PG, Lazarus SC. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med. 2014 Jun 05; 370(23):2201-10. PMID: 24836125; PMCID: PMC4375247.
    Citations: 50     Fields:    Translation:Humans
  83. Freeman CM, McCubbrey AL, Crudgington S, Nelson J, Martinez FJ, Han MK, Washko GR, Chensue SW, Arenberg DA, Meldrum CA, McCloskey L, Curtis JL. Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent. PLoS One. 2014; 9(5):e96421. PMID: 24805101; PMCID: PMC4013040.
    Citations: 10     Fields:    Translation:HumansCells
  84. Kim V, Davey A, Comellas AP, Han MK, Washko G, Martinez CH, Lynch D, Lee JH, Silverman EK, Crapo JD, Make BJ, Criner GJ. Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study. Respir Res. 2014 Apr 27; 15:52. PMID: 24766722.
    Citations: 18     Fields:    Translation:Humans
  85. Petersen H, Sood A, Meek PM, Shen X, Cheng Y, Belinsky SA, Owen CA, Washko G, Pinto-Plata V, Kelly E, Celli B, Tesfaigzi Y. Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use. Chest. 2014 Apr; 145(4):695-703. PMID: 24008986; PMCID: PMC3971967.
    Citations: 14     Fields:    Translation:Humans
  86. Ross JC, Díaz AA, Okajima Y, Wassermann D, Washko GR, Dy J, San José Estépar R. AIRWAY LABELING USING A HIDDEN MARKOV TREE MODEL. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:554-558. PMID: 25436039.
    Citations:    
  87. Kurugol S, Washko GR, Estepar RS. RANKING AND CLASSIFICATION OF MONOTONIC EMPHYSEMA PATTERNS WITH A MULTI-CLASS HIERARCHICAL APPROACH. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:1031-1034. PMID: 25485040.
    Citations:    
  88. McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, Macnee W, Rennard SI, Lomas DA, Agusti A, Celli BR, Black-Shinn JL, Kinney GL, Lutz SM, Hokanson JE, Silverman EK, Washko GR. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Ann Am Thorac Soc. 2014 Mar; 11(3):326-34. PMID: 24558953.
    Citations: 19     Fields:    Translation:Humans
  89. Rahaghi FN, van Beek EJ, Washko GR. Cardiopulmonary coupling in chronic obstructive pulmonary disease: the role of imaging. J Thorac Imaging. 2014 Mar; 29(2):80-91. PMID: 24552883; PMCID: PMC4274316.
    Citations: 4     Fields:    Translation:Humans
  90. Castaldi PJ, Dy J, Ross J, Chang Y, Washko GR, Curran-Everett D, Williams A, Lynch DA, Make BJ, Crapo JD, Bowler RP, Regan EA, Hokanson JE, Kinney GL, Han MK, Soler X, Ramsdell JW, Barr RG, Foreman M, van Beek E, Casaburi R, Criner GJ, Lutz SM, Rennard SI, Santorico S, Sciurba FC, DeMeo DL, Hersh CP, Silverman EK, Cho MH. Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema. Thorax. 2014 May; 69(5):415-22. PMID: 24563194.
    Citations: 21     Fields:    Translation:Humans
  91. Gazourian L, Rogers AJ, Ibanga R, Weinhouse GL, Pinto-Plata V, Ritz J, Soiffer RJ, Antin JH, Washko GR, Baron RM, Ho VT. Factors associated with bronchiolitis obliterans syndrome and chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation. Am J Hematol. 2014 Apr; 89(4):404-9. PMID: 24375545; PMCID: PMC4314109.
    Citations: 5     Fields:    Translation:HumansCells
  92. Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JH, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, Groen HJ, Postma DS, Wanner A, Rouhani FN, Brantly ML, Powell R, Smith BM, Rabinowitz D, Raffel LJ, Hinckley Stukovsky KD, Crapo JD, Beaty TH, Hokanson JE, Silverman EK, Dupuis J, O'Connor GT, Boezen HM, Rich SS, Barr RG. Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study. Am J Respir Crit Care Med. 2014 Feb 15; 189(4):408-18. PMID: 24383474.
    Citations: 30     Fields:    Translation:Humans
  93. Kinsey CM, Estepar RS, Zhao Y, Yu X, Diao N, Heist RS, Wain JC, Mark EJ, Washko G, Christiani DC. Invasive adenocarcinoma of the lung is associated with the upper lung regions. Lung Cancer. 2014 May; 84(2):145-50. PMID: 24598367.
    Citations: 6     Fields:    Translation:Humans
  94. Diaz AA, Come CE, Mannino DM, Pinto-Plata V, Divo MJ, Bigelow C, Celli B, Washko GR. Obstructive lung disease in Mexican Americans and non-Hispanic whites: an analysis of diagnosis and survival in the National Health and Nutritional Examination Survey III Follow-up Study. Chest. 2014 Feb; 145(2):282-289. PMID: 24077252; PMCID: PMC3913298.
    Citations: 4     Fields:    Translation:Humans
  95. Washko GR, Diaz AA, Kim V, Barr RG, Dransfield MT, Schroeder J, Reilly JJ, Ramsdell JW, McKenzie A, Van Beek EJ, Lynch DA, Butler JP, Han MK. Computed tomographic measures of airway morphology in smokers and never-smoking normals. J Appl Physiol (1985). 2014 Mar 15; 116(6):668-73. PMID: 24436301; PMCID: PMC3949240.
    Citations: 8     Fields:    Translation:Humans
  96. Ross JC, Kindlmann GL, Okajima Y, Hatabu H, Díaz AA, Silverman EK, Washko GR, Dy J, San José Estépar R. Pulmonary lobe segmentation based on ridge surface sampling and shape model fitting. Med Phys. 2013 Dec; 40(12):121903. PMID: 24320514.
    Citations: 2     Fields:    Translation:Humans
  97. Rice MB, Ljungman PL, Wilker EH, Gold DR, Schwartz JD, Koutrakis P, Washko GR, O'Connor GT, Mittleman MA. Short-term exposure to air pollution and lung function in the Framingham Heart Study. Am J Respir Crit Care Med. 2013 Dec 01; 188(11):1351-7. PMID: 24200465; PMCID: PMC3919078.
    Citations: 30     Fields:    Translation:HumansPHPublic Health
  98. Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Kim HP, Mahmood A, Biswal SS, Ryter SW, Choi AM. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. J Clin Invest. 2013 Dec; 123(12):5212-30. PMID: 24200693; PMCID: PMC3859407.
    Citations: 68     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  99. Castaldi PJ, San José Estépar R, Mendoza CS, Hersh CP, Laird N, Crapo JD, Lynch DA, Silverman EK, Washko GR. Distinct quantitative computed tomography emphysema patterns are associated with physiology and function in smokers. Am J Respir Crit Care Med. 2013 Nov 01; 188(9):1083-90. PMID: 23980521.
    Citations: 34     Fields:    Translation:Humans
  100. Kim V, Sternberg AL, Washko G, Make BJ, Han MK, Martinez F, Criner GJ. Severe chronic bronchitis in advanced emphysema increases mortality and hospitalizations. COPD. 2013 Dec; 10(6):667-78. PMID: 23978192.
    Citations: 10     Fields:    Translation:Humans
  101. Estépar RS, Kinney GL, Black-Shinn JL, Bowler RP, Kindlmann GL, Ross JC, Kikinis R, Han MK, Come CE, Diaz AA, Cho MH, Hersh CP, Schroeder JD, Reilly JJ, Lynch DA, Crapo JD, Wells JM, Dransfield MT, Hokanson JE, Washko GR. Computed tomographic measures of pulmonary vascular morphology in smokers and their clinical implications. Am J Respir Crit Care Med. 2013 Jul 15; 188(2):231-9. PMID: 23656466.
    Citations: 40     Fields:    Translation:Humans
  102. Come CE, Diaz AA, Curran-Everett D, Muralidhar N, Hersh CP, Zach JA, Schroeder J, Lynch DA, Celli B, Washko GR. Characterizing functional lung heterogeneity in COPD using reference equations for CT scan-measured lobar volumes. Chest. 2013 Jun; 143(6):1607-1617. PMID: 23699785; PMCID: PMC3673661.
    Citations: 6     Fields:    Translation:Humans
  103. Hunninghake GM, Hatabu H, Okajima Y, Gao W, Dupuis J, Latourelle JC, Nishino M, Araki T, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Murphy E, Steele MP, Loyd JE, Schwarz MI, Fingerlin TE, Rosas IO, Washko GR, O'Connor GT, Schwartz DA. MUC5B promoter polymorphism and interstitial lung abnormalities. N Engl J Med. 2013 Jun 06; 368(23):2192-200. PMID: 23692170; PMCID: PMC3747636.
    Citations: 64     Fields:    Translation:Humans
  104. Hersh CP, Washko GR, Estépar RS, Lutz S, Friedman PJ, Han MK, Hokanson JE, Judy PF, Lynch DA, Make BJ, Marchetti N, Newell JD, Sciurba FC, Crapo JD, Silverman EK. Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD. Respir Res. 2013 Apr 08; 14:42. PMID: 23566024; PMCID: PMC3627637.
    Citations: 22     Fields:    Translation:Humans
  105. Bhatt SP, Sieren JC, Dransfield MT, Washko GR, Newell JD, Stinson DS, Zamba GK, Hoffman EA. Comparison of spirometric thresholds in diagnosing smoking-related airflow obstruction. Thorax. 2014 May; 69(5):409-14. PMID: 23525095; PMCID: PMC4146523.
    Citations: 16     Fields:    Translation:Humans
  106. Diaz AA, Han MK, Come CE, San José Estépar R, Ross JC, Kim V, Dransfield MT, Curran-Everett D, Schroeder JD, Lynch DA, Tschirren J, Silverman EK, Washko GR. Effect of emphysema on CT scan measures of airway dimensions in smokers. Chest. 2013 Mar; 143(3):687-693. PMID: 23460155; PMCID: PMC3590885.
    Citations: 11     Fields:    Translation:Humans
  107. Freeman CM, Martinez FJ, Han MK, Washko GR, McCubbrey AL, Chensue SW, Arenberg DA, Meldrum CA, McCloskey L, Curtis JL. Lung CD8+ T cells in COPD have increased expression of bacterial TLRs. Respir Res. 2013 Feb 01; 14:13. PMID: 23374856.
    Citations: 23     Fields:    Translation:HumansCellsCTClinical Trials
  108. Hansel NN, Washko GR, Foreman MG, Han MK, Hoffman EA, DeMeo DL, Barr RG, Van Beek EJ, Kazerooni EA, Wise RA, Brown RH, Black-Shinn J, Hokanson JE, Hanania NA, Make B, Silverman EK, Crapo JD, Dransfield MT. Racial differences in CT phenotypes in COPD. COPD. 2013 Feb; 10(1):20-7. PMID: 23413893; PMCID: PMC4321889.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  109. Díaz AA, Morales A, Díaz JC, Ramos C, Klaassen J, Saldías F, Aravena C, Díaz R, Lisboa C, Washko GR, Díaz O. CT and physiologic determinants of dyspnea and exercise capacity during the six-minute walk test in mild COPD. Respir Med. 2013 Apr; 107(4):570-9. PMID: 23313036.
    Citations: 13     Fields:    Translation:Humans
  110. Wassermann D, Ross J, Washko G, Westin CF, Estépar RS. DIFFEOMORPHIC POINT SET REGISTRATION USING NON-STATIONARY MIXTURE MODELS. Proc IEEE Int Symp Biomed Imaging. 2013. PMID: 24419463.
    Citations: 2     
  111. Gazourian L, Coronata AM, Rogers AJ, Weinhouse GL, Soiffer RJ, Antin JH, Ritz J, Ho VT, Baron RM, Washko GR. Airway dilation in bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation. Respir Med. 2013 Feb; 107(2):276-83. PMID: 23195332; PMCID: PMC3543517.
    Citations: 3     Fields:    Translation:Humans
  112. An CH, Wang XM, Lam HC, Ifedigbo E, Washko GR, Ryter SW, Choi AM. TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 01; 303(9):L748-57. PMID: 22983353.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  113. Wells JM, Washko GR, Han MK, Abbas N, Nath H, Mamary AJ, Regan E, Bailey WC, Martinez FJ, Westfall E, Beaty TH, Curran-Everett D, Curtis JL, Hokanson JE, Lynch DA, Make BJ, Crapo JD, Silverman EK, Bowler RP, Dransfield MT. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med. 2012 Sep 06; 367(10):913-21. PMID: 22938715; PMCID: PMC3690810.
    Citations: 90     Fields:    Translation:Humans
  114. Han MK, Muellerova H, Curran-Everett D, Dransfield MT, Washko GR, Regan EA, Bowler RP, Beaty TH, Hokanson JE, Lynch DA, Jones PW, Anzueto A, Martinez FJ, Crapo JD, Silverman EK, Make BJ. GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med. 2013 Mar; 1(1):43-50. PMID: 24321803; PMCID: PMC4105297.
    Citations: 54     Fields:    Translation:HumansCTClinical Trials
  115. Washko GR. The role and potential of imaging in COPD. Med Clin North Am. 2012 Jul; 96(4):729-43. PMID: 22793941; PMCID: PMC4004058.
    Citations: 2     Fields:    Translation:Humans
  116. Dransfield MT, Harnden S, Burton RL, Albert RK, Bailey WC, Casaburi R, Connett J, Cooper JA, Criner GJ, Curtis JL, Han MK, Make B, Marchetti N, Martinez FJ, McEvoy C, Nahm MH, Niewoehner DE, Porszasz J, Reilly J, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Woodruff PG, Lazarus SC. Long-term comparative immunogenicity of protein conjugate and free polysaccharide pneumococcal vaccines in chronic obstructive pulmonary disease. Clin Infect Dis. 2012 Sep; 55(5):e35-44. PMID: 22652582; PMCID: PMC3491850.
    Citations: 11     Fields:    Translation:Humans
  117. Martinez CH, Chen YH, Westgate PM, Liu LX, Murray S, Curtis JL, Make BJ, Kazerooni EA, Lynch DA, Marchetti N, Washko GR, Martinez FJ, Han MK. Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease. Thorax. 2012 May; 67(5):399-406. PMID: 22514236; PMCID: PMC3719874.
    Citations: 36     Fields:    Translation:Humans
  118. Washko GR, Parraga G, Coxson HO. Quantitative pulmonary imaging using computed tomography and magnetic resonance imaging. Respirology. 2012 Apr; 17(3):432-44. PMID: 22142490; PMCID: PMC3312990.
    Citations: 15     Fields:    Translation:Humans
  119. Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, Erikkson L, Friedlander A, Galperin-Aizenberg M, Gefter WB, Gierada DS, Grenier PA, Goldin J, Han MK, Hanania NA, Hansel NN, Jacobson FL, Kauczor HU, Kinnula VL, Lipson DA, Lynch DA, MacNee W, Make BJ, Mamary AJ, Mann H, Marchetti N, Mascalchi M, McLennan G, Murphy JR, Naidich D, Nath H, Newell JD, Pistolesi M, Regan EA, Reilly JJ, Sandhaus R, Schroeder JD, Sciurba F, Shaker S, Sharafkhaneh A, Silverman EK, Steiner RM, Strange C, Sverzellati N, Tashjian JH, van Beek EJ, Washington L, Washko GR, Westney G, Wood SA, Woodruff PG. A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. COPD. 2012 Apr; 9(2):151-9. PMID: 22429093; PMCID: PMC3752926.
    Citations: 49     Fields:    Translation:Humans
  120. Milne EN, Han MK, Washko GR. Parturient Montes. Radiology. 2012 Mar; 262(3):1042; author reply 1043. PMID: 22357905.
    Citations:    Fields:    Translation:Humans
  121. Doyle TJ, Washko GR, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Divo MJ, Celli BR, Sciurba FC, Silverman EK, Hatabu H, Rosas IO, Hunninghake GM. Interstitial lung abnormalities and reduced exercise capacity. Am J Respir Crit Care Med. 2012 Apr 01; 185(7):756-62. PMID: 22268134; PMCID: PMC3326424.
    Citations: 27     Fields:    Translation:Humans
  122. Xu JF, Washko GR, Nakahira K, Hatabu H, Patel AS, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Diaz AA, Li HP, Qu JM, Himes BE, Come CE, D'Aco K, Martinez FJ, Han MK, Lynch DA, Crapo JD, Morse D, Ryter SW, Silverman EK, Rosas IO, Choi AM, Hunninghake GM. Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. Am J Respir Crit Care Med. 2012 Mar 01; 185(5):547-56. PMID: 22246178; PMCID: PMC3297101.
    Citations: 26     Fields:    Translation:HumansAnimals
  123. Washko GR. Rate of decline in FEV1: is emphysema the culprit? Am J Respir Crit Care Med. 2012 Jan 01; 185(1):2-3. PMID: 22210781.
    Citations: 4     Fields:    Translation:Humans
  124. Kurugol S, San Jose Estepar R, Ross J, Washko GR. Aorta segmentation with a 3D level set approach and quantification of aortic calcifications in non-contrast chest CT. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:2343-6. PMID: 23366394; PMCID: PMC3671590.
    Citations: 7     Fields:    Translation:Humans
  125. Estépar RS, Ross JC, Krissian K, Schultz T, Washko GR, Kindlmann GL. COMPUTATIONAL VASCULAR MORPHOMETRY FOR THE ASSESSMENT OF PULMONARY VASCULAR DISEASE BASED ON SCALE-SPACE PARTICLES. Proc IEEE Int Symp Biomed Imaging. 2012; 1479-1482. PMID: 23743962.
    Citations: 11     
  126. Diaz AA, Come CE, Ross JC, San José Estépar R, Han MK, Loring SH, Silverman EK, Washko GR. Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD. Chest. 2012 Mar; 141(3):736-744. PMID: 21940776; PMCID: PMC3296457.
    Citations: 20     Fields:    Translation:Humans
  127. Albert RK, Connett J, Bailey WC, Casaburi R, Cooper JA, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Make B, Marchetti N, Martinez FJ, Madinger NE, McEvoy C, Niewoehner DE, Porsasz J, Price CS, Reilly J, Scanlon PD, Sciurba FC, Scharf SM, Washko GR, Woodruff PG, Anthonisen NR. Azithromycin for prevention of exacerbations of COPD. N Engl J Med. 2011 Aug 25; 365(8):689-98. PMID: 21864166; PMCID: PMC3220999.
    Citations: 207     Fields:    Translation:Humans
  128. Come CE, Divo MJ, San José Estépar R, Sciurba FC, Criner GJ, Marchetti N, Scharf SM, Mosenifar Z, Make BJ, Keller CA, Minai OA, Martinez FJ, Han MK, Reilly JJ, Celli BR, Washko GR. Lung deflation and oxygen pulse in COPD: results from the NETT randomized trial. Respir Med. 2012 Jan; 106(1):109-19. PMID: 21843930; PMCID: PMC3233645.
    Citations: 11     Fields:    Translation:Humans
  129. Foreman MG, Zhang L, Murphy J, Hansel NN, Make B, Hokanson JE, Washko G, Regan EA, Crapo JD, Silverman EK, DeMeo DL. Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study. Am J Respir Crit Care Med. 2011 Aug 15; 184(4):414-20. PMID: 21562134; PMCID: PMC3175544.
    Citations: 35     Fields:    Translation:Humans
  130. Han MK, Kazerooni EA, Lynch DA, Liu LX, Murray S, Curtis JL, Criner GJ, Kim V, Bowler RP, Hanania NA, Anzueto AR, Make BJ, Hokanson JE, Crapo JD, Silverman EK, Martinez FJ, Washko GR. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology. 2011 Oct; 261(1):274-82. PMID: 21788524.
    Citations: 99     Fields:    Translation:Humans
  131. Kim YI, Schroeder J, Lynch D, Newell J, Make B, Friedlander A, Estépar RS, Hanania NA, Washko G, Murphy JR, Wilson C, Hokanson JE, Zach J, Butterfield K, Bowler RP. Gender differences of airway dimensions in anatomically matched sites on CT in smokers. COPD. 2011 Aug; 8(4):285-92. PMID: 21756032; PMCID: PMC3703311.
    Citations: 11     Fields:    Translation:Humans
  132. Okajima Y, Ohno Y, Washko GR, Hatabu H. Assessment of pulmonary hypertension what CT and MRI can provide. Acad Radiol. 2011 Apr; 18(4):437-53. PMID: 21377593.
    Citations: 9     Fields:    Translation:Humans
  133. Washko GR, Hunninghake GM, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Lynch DA, Brehm JM, Andriole KP, Diaz AA, Khorasani R, D'Aco K, Sciurba FC, Silverman EK, Hatabu H, Rosas IO. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med. 2011 Mar 10; 364(10):897-906. PMID: 21388308; PMCID: PMC3074462.
    Citations: 110     Fields:    Translation:Humans
  134. Kim DK, Jacobson FL, Washko GR, Casaburi R, Make BJ, Crapo JD, Silverman EK, Hersh CP. Clinical and radiographic correlates of hypoxemia and oxygen therapy in the COPDGene study. Respir Med. 2011 Aug; 105(8):1211-21. PMID: 21396809; PMCID: PMC3116986.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  135. Hersh CP, Hokanson JE, Lynch DA, Washko GR, Make BJ, Crapo JD, Silverman EK. Family history is a risk factor for COPD. Chest. 2011 Aug; 140(2):343-350. PMID: 21310839; PMCID: PMC3198493.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  136. Woodruff PG, Albert RK, Bailey WC, Casaburi R, Connett JE, Cooper JA, Criner GJ, Curtis JL, Dransfield MT, Han MK, Harnden SM, Kim V, Marchetti N, Martinez FJ, McEvoy CE, Niewoehner DE, Reilly JJ, Rice K, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Lazarus SC. Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization. COPD. 2011 Feb; 8(1):21-9. PMID: 21299475; PMCID: PMC3775706.
    Citations: 8     Fields:    Translation:Humans
  137. Yamashiro T, Matsuoka S, Estépar RS, Bartholmai BJ, Diaz A, Ross JC, Murayama S, Silverman EK, Hatabu H, Washko GR. Kurtosis and skewness of density histograms on inspiratory and expiratory CT scans in smokers. COPD. 2011 Feb; 8(1):13-20. PMID: 21299474.
    Citations: 4     Fields:    Translation:Humans
  138. Kim DK, Hersh CP, Washko GR, Hokanson JE, Lynch DA, Newell JD, Murphy JR, Crapo JD, Silverman EK. Epidemiology, radiology, and genetics of nicotine dependence in COPD. Respir Res. 2011 Jan 13; 12:9. PMID: 21232152.
    Citations: 20     Fields:    Translation:Humans
  139. Yamashiro T, San José Estépar R, Matsuoka S, Bartholmai BJ, Ross JC, Diaz A, Murayama S, Silverman EK, Hatabu H, Washko GR. Intrathoracic tracheal volume and collapsibility on inspiratory and end-expiratory ct scans correlations with lung volume and pulmonary function in 85 smokers. Acad Radiol. 2011 Mar; 18(3):299-305. PMID: 21215660; PMCID: PMC3035420.
    Citations: 7     Fields:    Translation:Humans
  140. Risholm P, Ross J, Washko GR, Wells WM. Probabilistic elastography: estimating lung elasticity. Inf Process Med Imaging. 2011; 22:699-710. PMID: 21761697; PMCID: PMC3249413.
    Citations: 2     Fields:    Translation:Humans
  141. Dransfield MT, Huang F, Nath H, Singh SP, Bailey WC, Washko GR. CT emphysema predicts thoracic aortic calcification in smokers with and without COPD. COPD. 2010 Dec; 7(6):404-10. PMID: 21166628.
    Citations: 4     Fields:    Translation:Humans
  142. Matsuoka S, Yamashiro T, Diaz A, Estépar RS, Ross JC, Silverman EK, Kobayashi Y, Dransfield MT, Bartholmai BJ, Hatabu H, Washko GR. The relationship between small pulmonary vascular alteration and aortic atherosclerosis in chronic obstructive pulmonary disease: quantitative CT analysis. Acad Radiol. 2011 Jan; 18(1):40-6. PMID: 20947389; PMCID: PMC3006041.
    Citations: 16     Fields:    Translation:Humans
  143. Kong X, Cho MH, Anderson W, Coxson HO, Muller N, Washko G, Hoffman EA, Bakke P, Gulsvik A, Lomas DA, Silverman EK, Pillai SG. Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Am J Respir Crit Care Med. 2011 Jan 01; 183(1):43-9. PMID: 20709820; PMCID: PMC3040393.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  144. Yamashiro T, Matsuoka S, Estépar RS, Dransfield MT, Diaz A, Reilly JJ, Patz S, Murayama S, Silverman EK, Hatabu H, Washko GR. Quantitative assessment of bronchial wall attenuation with thin-section CT: An indicator of airflow limitation in chronic obstructive pulmonary disease. AJR Am J Roentgenol. 2010 Aug; 195(2):363-9. PMID: 20651191.
    Citations: 15     Fields:    Translation:Humans
  145. Sørheim IC, DeMeo DL, Washko G, Litonjua A, Sparrow D, Bowler R, Bakke P, Pillai SG, Coxson HO, Lomas DA, Silverman EK, Hersh CP. Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD. COPD. 2010 Aug; 7(4):262-8. PMID: 20673035; PMCID: PMC2923920.
    Citations: 19     Fields:    Translation:Humans
  146. Diaz AA, Valim C, Yamashiro T, Estépar RS, Ross JC, Matsuoka S, Bartholmai B, Hatabu H, Silverman EK, Washko GR. Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers. Chest. 2010 Oct; 138(4):880-7. PMID: 20558554.
    Citations: 23     Fields:    Translation:Humans
  147. Chandra D, Lipson DA, Hoffman EA, Hansen-Flaschen J, Sciurba FC, Decamp MM, Reilly JJ, Washko GR. Perfusion scintigraphy and patient selection for lung volume reduction surgery. Am J Respir Crit Care Med. 2010 Oct 01; 182(7):937-46. PMID: 20538961; PMCID: PMC2970864.
    Citations: 7     Fields:    Translation:Humans
  148. Kim WJ, Hoffman E, Reilly J, Hersh C, Demeo D, Washko G, Silverman EK. Association of COPD candidate genes with computed tomography emphysema and airway phenotypes in severe COPD. Eur Respir J. 2011 Jan; 37(1):39-43. PMID: 20525719; PMCID: PMC3074301.
    Citations: 13     Fields:    Translation:Humans
  149. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, Macnee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, Vestbo J, Washko GR, Wouters EF, Martinez FJ. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):598-604. PMID: 20522794.
    Citations: 200     Fields:    Translation:Humans
  150. Washko GR. Diagnostic imaging in COPD. Semin Respir Crit Care Med. 2010 Jun; 31(3):276-85. PMID: 20496297; PMCID: PMC4334134.
    Citations: 13     Fields:    Translation:HumansPHPublic Health
  151. Diaz AA, Bartholmai B, San José Estépar R, Ross J, Matsuoka S, Yamashiro T, Hatabu H, Reilly JJ, Silverman EK, Washko GR. Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD. Respir Med. 2010 Aug; 104(8):1145-51. PMID: 20385477; PMCID: PMC2904840.
    Citations: 22     Fields:    Translation:Humans
  152. Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res. 2010 Mar 16; 11:30. PMID: 20233420; PMCID: PMC2850331.
    Citations: 18     Fields:    Translation:Humans
  153. Wan ES, Pober BR, Washko GR, Raby BA, Silverman EK. Pulmonary function and emphysema in Williams-Beuren syndrome. Am J Med Genet A. 2010 Mar; 152A(3):653-6. PMID: 20186780; PMCID: PMC3397670.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  154. Nishino M, Washko GR, Hatabu H. Volumetric expiratory HRCT of the lung: clinical applications. Thorac Surg Clin. 2010 Feb; 20(1):121-7, viii-ix. PMID: 20378064.
    Citations:    Fields:    
  155. Yamashiro T, Matsuoka S, Bartholmai BJ, San José Estépar R, Ross JC, Diaz A, Murayama S, Silverman EK, Hatabu H, Washko GR. Collapsibility of lung volume by paired inspiratory and expiratory CT scans: correlations with lung function and mean lung density. Acad Radiol. 2010 Apr; 17(4):489-95. PMID: 20060751; PMCID: PMC2834821.
    Citations: 26     Fields:    Translation:Humans
  156. Ross JC, San José Estépar R, Kindlmann G, Díaz A, Westin CF, Silverman EK, Washko GR. Automatic lung lobe segmentation using particles, thin plate splines, and maximum a posteriori estimation. Med Image Comput Comput Assist Interv. 2010; 13(Pt 3):163-71. PMID: 20879396; PMCID: PMC3049444.
    Citations: 8     Fields:    Translation:Humans
  157. Matsuoka S, Yamashiro T, Washko GR, Kurihara Y, Nakajima Y, Hatabu H. Quantitative CT assessment of chronic obstructive pulmonary disease. Radiographics. 2010 Jan; 30(1):55-66. PMID: 20083585.
    Citations: 27     Fields:    Translation:Humans
  158. Nishino M, Washko GR, Hatabu H. Volumetric expiratory HRCT of the lung: clinical applications. Radiol Clin North Am. 2010 Jan; 48(1):177-83. PMID: 19995635.
    Citations: 2     Fields:    Translation:Humans
  159. Washko GR, Martinez FJ, Hoffman EA, Loring SH, Estépar RS, Diaz AA, Sciurba FC, Silverman EK, Han MK, Decamp M, Reilly JJ. Physiological and computed tomographic predictors of outcome from lung volume reduction surgery. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):494-500. PMID: 19965810; PMCID: PMC2830400.
    Citations: 13     Fields:    Translation:Humans
  160. Yamashiro T, Matsuoka S, Estépar RS, Diaz A, Newell JD, Sandhaus RA, Mergo PJ, Brantly ML, Murayama S, Reilly JJ, Hatabu H, Silverman EK, Washko GR. Quantitative airway assessment on computed tomography in patients with alpha1-antitrypsin deficiency. COPD. 2009 Dec; 6(6):468-77. PMID: 19938971; PMCID: PMC2945281.
    Citations: 5     Fields:    Translation:Humans
  161. Matsuoka S, Washko GR, Yamashiro T, Estepar RS, Diaz A, Silverman EK, Hoffman E, Fessler HE, Criner GJ, Marchetti N, Scharf SM, Martinez FJ, Reilly JJ, Hatabu H. Pulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema. Am J Respir Crit Care Med. 2010 Feb 01; 181(3):218-25. PMID: 19875683; PMCID: PMC2817812.
    Citations: 34     Fields:    Translation:Humans
  162. Matsuoka S, Washko GR, Dransfield MT, Yamashiro T, San Jose Estepar R, Diaz A, Silverman EK, Patz S, Hatabu H. Quantitative CT measurement of cross-sectional area of small pulmonary vessel in COPD: correlations with emphysema and airflow limitation. Acad Radiol. 2010 Jan; 17(1):93-9. PMID: 19796970; PMCID: PMC2790546.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  163. Washko GR, Lynch DA, Matsuoka S, Ross JC, Umeoka S, Diaz A, Sciurba FC, Hunninghake GM, San José Estépar R, Silverman EK, Rosas IO, Hatabu H. Identification of early interstitial lung disease in smokers from the COPDGene Study. Acad Radiol. 2010 Jan; 17(1):48-53. PMID: 19781963; PMCID: PMC2790552.
    Citations: 48     Fields:    Translation:Humans
  164. Dransfield MT, Nahm MH, Han MK, Harnden S, Criner GJ, Martinez FJ, Scanlon PD, Woodruff PG, Washko GR, Connett JE, Anthonisen NR, Bailey WC. Superior immune response to protein-conjugate versus free pneumococcal polysaccharide vaccine in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009 Sep 15; 180(6):499-505. PMID: 19556517; PMCID: PMC2742743.
    Citations: 20     Fields:    Translation:HumansCells
  165. Kim WJ, Silverman EK, Hoffman E, Criner GJ, Mosenifar Z, Sciurba FC, Make BJ, Carey V, San José Estépar R, Diaz A, Reilly JJ, Martinez FJ, Washko GR. CT metrics of airway disease and emphysema in severe COPD. Chest. 2009 Aug; 136(2):396-404. PMID: 19411295; PMCID: PMC2733947.
    Citations: 36     Fields:    Translation:Humans
  166. Washko GR, Dransfield MT, Estépar RS, Diaz A, Matsuoka S, Yamashiro T, Hatabu H, Silverman EK, Bailey WC, Reilly JJ. Airway wall attenuation: a biomarker of airway disease in subjects with COPD. J Appl Physiol (1985). 2009 Jul; 107(1):185-91. PMID: 19407254.
    Citations: 25     Fields:    Translation:Humans
  167. Ross JC, Estépar RS, Díaz A, Westin CF, Kikinis R, Silverman EK, Washko GR. Lung extraction, lobe segmentation and hierarchical region assessment for quantitative analysis on high resolution computed tomography images. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):690-8. PMID: 20426172; PMCID: PMC3061233.
    Citations: 20     Fields:    Translation:Humans
  168. San José Estépar R, Reilly JJ, Silverman EK, Washko GR. Three-dimensional airway measurements and algorithms. Proc Am Thorac Soc. 2008 Dec 15; 5(9):905-9. PMID: 19056714.
    Citations: 6     Fields:    Translation:Humans
  169. Tzeng YS, Hoffman E, Cook-Granroth J, Gereige J, Mansour J, Washko G, Cho M, Stepp E, Lutchen K, Albert M. Investigation of hyperpolarized 3He magnetic resonance imaging utility in examining human airway diameter behavior in asthma through comparison with high-resolution computed tomography. Acad Radiol. 2008 Jun; 15(6):799-808. PMID: 18486015; PMCID: PMC2587251.
    Citations: 8     Fields:    Translation:Humans
  170. Washko GR, Criner GJ, Mohsenifar Z, Sciurba FC, Sharafkhaneh A, Make BJ, Hoffman EA, Reilly JJ. Computed tomographic-based quantification of emphysema and correlation to pulmonary function and mechanics. COPD. 2008 Jun; 5(3):177-86. PMID: 18568842.
    Citations: 36     Fields:    Translation:Humans
  171. Washko GR, Hoffman E, Reilly JJ. Radiographic evaluation of the potential lung volume reduction surgery candidate. Proc Am Thorac Soc. 2008 May 01; 5(4):421-6. PMID: 18453349; PMCID: PMC2645313.
    Citations: 6     Fields:    Translation:Humans
  172. Washko GR, Criner GJ, Mohsenifar Z, Sciurba FC, Sharafkhaneh A, Make BJ, Hoffman EA, Reilly JJ, for the NETT Research Group. CT based quantification of emphysema and correlation to lung function and mechanics. COPD: Journal of Chronic Obstructive Pulmonary Disease. 2008; 5(3 ):177-186.
  173. Washko GR, Fan VS, Ramsey SD, Mohsenifar Z, Martinez F, Make BJ, Sciurba FC, Criner GJ, Minai O, Decamp MM, Reilly JJ. The effect of lung volume reduction surgery on chronic obstructive pulmonary disease exacerbations. Am J Respir Crit Care Med. 2008 Jan 15; 177(2):164-9. PMID: 17962632; PMCID: PMC2204077.
    Citations: 17     Fields:    Translation:Humans
  174. Dransfield MT, Washko GR, Foreman MG, Estepar RS, Reilly J, Bailey WC. Gender differences in the severity of CT emphysema in COPD. Chest. 2007 Aug; 132(2):464-70. PMID: 17573503.
    Citations: 39     Fields:    Translation:Humans
  175. Reilly J, Washko G, Pinto-Plata V, Velez E, Kenney L, Berger R, Celli B. Biological lung volume reduction: a new bronchoscopic therapy for advanced emphysema. Chest. 2007 Apr; 131(4):1108-13. PMID: 17426216.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  176. Hersh CP, Washko GR, Jacobson FL, Gill R, Estepar RS, Reilly JJ, Silverman EK. Interobserver variability in the determination of upper lobe-predominant emphysema. Chest. 2007 Feb; 131(2):424-31. PMID: 17296643.
    Citations: 30     Fields:    Translation:Humans
  177. M.T. Dransfield, M.D., G.R. Washko, M.D., J. Reilly, M.D., W.C. Bailey, M.D. 2007. . Gender Differences in the Severity of CT Emphysema in COPD. Am J Respir Crit Care Med (Abstracts Issue). 2007; 175:A613.
  178. N.D. Giardino, J.L. Curtis, V. Fan, K. Naunheim, G. Criner, B. Make, R. Wise, A. Fishman, G. Weinmann, G. Washko, F. Sciurba, S. Scharf, F.J. Martinez. . Maladaptive Beliefs Mediate of the Association between Anxiety and Impaired Exercise Performance in Severe COPD. Am J Respir Crit Care Med (Abstracts Issue). 2007; 175:A548.
  179. Y.-S. Tzeng, SM., J. Gereige, B.S., J.B. Szender, B.S., S. Zhalehdoust-Sani, B.S., G.R. Washko, M.D., M.H. Cho, M.D., E. Stepp, M.D., M.S. Albert, PhD., K.R. Lutchen, PhD. Similar Responses to Deep Inspirations Observed in Reactive and Non-Reactive Asthmatic Subjects using Hyperpolarized 3He MRI. Am J Respir Crit Care Med 175(Abstracts Issue). 2007; 175:A332.
  180. E. Sen, M.D., G.R. Washko, M.D., J.J. Reilly, M.D. . The Relationship of Radiographic and Functional Changes of the Lung after Bronchoscopic Lung Volume Reduction: an Observational Report from a Phase 1 Investigation. Am J Respir Crit Care Med(Abstracts Issue). 2007; 175:A811.
  181. G.R. Washko, M.D., V.S. Fan, M.D., M., S.D. Ramsey, M.D., Ph, J.J. Reilly, M.D. . The Effect of Lung Volume Reduction Surgery on Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med (Abstracts Issue). 2007; 175:A812.
  182. Raul San Jose Estepar, Ph.D. Department of Radiology, George Washko, M.D. Pulmonary Division, John J. Reilly, M.D., Pulmonary Division, Edwin K.Silverman, M.D.,Ph.D., Carl-Fredrik Westin, M.D., Ph.D., Pulmonary Division, Ron Kikinis, M.D., Department of Radiology. A method for the accurate measurement of thin layered structures in X-ray computer tomography. 2007.
  183. R. San Jose Estepar, PhD., G.R. Washko, M.D., C.F. Westin, PhD., R. Kikinis, M.D., E.K. Silverman, M.D., Ph, J.J. Reilly, M.D. Using Multiple Reconstruction Kernels to Obtain Accurate Measurements of Small Airway Wall Thickness. Am J Respir Crit Care Med 175(Abstracts Issue). 2007; A250.
  184. George R. Washko M.D. The Correlation of Lung Structure and Function in COPD. 2006.
  185. G.R. Washko, M.D., S.H. Loring, M.D., J.J. Reilly, M.D. 2006. . Physiological Analysis of Response to Bronchoscopic Lung Volume Reduction via Tissue Engineering in Humans. Chest (Abstracts Issue). 2006; 180s.
  186. G.R. Washko, M.D., R.S.J. Estepar, Ph.D., C.F. Westin, Ph.D., R. Kikinis, M.D., E.K. Silverman, M.D. Ph., J.J. Reilly. 2006. . The Effect of Image Reconstruction on the Quantification of Emphysema By Density Mask Analysis. Am J Respir Crit Care Med (Abstracts Issue). 2006; A635.
  187. G.R. Washko, M.D., R.S.J. Estepar, Ph.D., C.F. Westin, Ph.D., R. Kikinis, M.D., E.K. Silverman, M.D. Ph., J.J. Reilly. The Effect of Kernel Selection on Quantitative Airways Analysis of Computed Tomographic Images of the Lung. Am J Respir Crit Care Med (Abstracts Issue). 2006; A127.
  188. R. San Jose Estepar, Ph.D., C.F. Westin, Ph.D., R. Kikinis, M.D., G.R. Washko, M.D., E.K. Silverman, M.D. Ph., J.J. Reilly. Computed Tomographic Analysis of the Lung with 3D Slicer: An Open Source Solution. Am J Respir Crit Care Med (Abstracts Issue). 2006; A127.
  189. Estépar RS, Washko GG, Silverman EK, Reilly JJ, Kikinis R, Westin CF. Accurate airway wall estimation using phase congruency. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):125-34. PMID: 17354764.
    Citations: 23     Fields:    Translation:Humans
  190. J. Kenyon, BS, S. Zhalehdoust, BS, J.B. Zender, MS, Y.S. Tzeng, SM, L.M. Campana, G.R. Washko, MD, E. Israel, MD, M.S. Albert, PhD, K.R. Lutchen. . Whole Lung Image Functional Modeling (IFM) Using Hyperpolarized Helium MRI (Hyp 3He MRI): Deep-Inspiration Response in Asthmatics. Am J Respir Crit Care Med (Abstracts Issue). 2006; A319.
  191. Y.-S. Tzeng, SM, N.M. Shah, BS, J.K. Mansour, MS, J.D. Gereige, BS, G.R. Washko, MD, E. Israel, MD, K.R. Lutchen, PhD, M.S. Albert, PhD. . Quantification of Ventilation heterogeneity Changes in Asthmatic and Non-Asthmatic Lungs Using Hyperpolarized 3He MRI. Am J Respir Crit Care Med (Abstracts Issue)2006. 2006; A63.
  192. Washko GR, O'Donnell CR, Loring SH. Volume-related and volume-independent effects of posture on esophageal and transpulmonary pressures in healthy subjects. J Appl Physiol (1985). 2006 Mar; 100(3):753-8. PMID: 16306256.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  193. George R. Washko MD, Lawrence Kenney MD, Victor Pinto-Plata MD, Bartolome Celli MD, John J. Reilly MD. Initial Experience with a Tissue Engineering Approach to Bronchoscopic Lung Volume Reduction in Humans with Emphysema. Chest. 2005; 128(4(Supplement)):496S.
  194. George R Washko MD, Raul San Jose Estepar PhD, Carl-Fredrik Westin PhD, Ron Kikinis MD, Stephen H. Loring MD, John J. Reilly MD. Computed Tomographic Measurement of Cartilaginous Airway Wall Thickening as a Predictor of Inspiratory Flow Resistance. Chest. 2005; 128(4 (Supplement)):159S.
  195. 4. Y.S. Tzeng, S.M., J.B. Szender, B.S., N.M. Shah, J.K. Mansour, M.S., P.A. Kritek, M.D., G.R. Washko, M.D., E.P. Ingenito, M.D., Ph.D., E. Israel, M.D., K.R. Lutchen, Ph.D., M.S. Albert, Ph.D. . Visualization and Quantification of Ventilation Heterogeneity in Healthy and Asthmatic Subjects Using Hyperpolarized 3He MRI. Am J Respir Crit Care Med(Abstracts Issue). 2005; A335.
  196. G.R. Washko, M.D., G.J. Criner, M.D., Z. Mohsenifar, M.D., F.C. Sciurba, M.D., A. Sharafkhaneh, M.D., B.J. Make, M.D. J. J. Reilly, M.D., for the NETT Research Group. 2005. Assessing Pulmonary Function with CT scanning in Patients with Emphysema. Am J Respir Crit Care Med(Abstracts Issue). 2005; A259.
  197. J.B. Szender, B.S., Y. Tzeng, S.M. G.R. Washko, M.D., P.A. Kritek, M.D., N.M. Shah, J.K. Mansour, M.S., E.P. Ingenito, M.D., Ph.D., E. Israel, M.D., M.S. Albert, Ph.D. K.R. Lutchen, Ph.D. . Impact of Deep-Inspirations on Ventilation and Mechanical Heterogeneity in Asthmatic Versus Healthy Lungs. Am J Respir Crit Care Med(Abstracts Issue). 2005; A563.
  198. Gerhard W, Mozdzanowska K, Furchner M, Washko G, Maiese K. Role of the B-cell response in recovery of mice from primary influenza virus infection. Immunol Rev. 1997 Oct; 159:95-103. PMID: 9416505.
    Citations: 91     Fields:    Translation:AnimalsCells
  199. Mozdzanowska K, Furchner M, Washko G, Mozdzanowski J, Gerhard W. A pulmonary influenza virus infection in SCID mice can be cured by treatment with hemagglutinin-specific antibodies that display very low virus-neutralizing activity in vitro. J Virol. 1997 Jun; 71(6):4347-55. PMID: 9151823; PMCID: PMC191651.
    Citations: 35     Fields:    Translation:AnimalsCells
  200. Galili U, Repik PM, Anaraki F, Mozdzanowska K, Washko G, Gerhard W. Enhancement of antigen presentation of influenza virus hemagglutinin by the natural human anti-Gal antibody. Vaccine. 1996 Mar; 14(4):321-8. PMID: 8744560.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  201. Palladino G, Mozdzanowska K, Washko G, Gerhard W. Virus-neutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice. J Virol. 1995 Apr; 69(4):2075-81. PMID: 7884853; PMCID: PMC188873.
    Citations: 62     Fields:    Translation:Animals
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.