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Emily Parker Hyle, M.D.


Williams College, Williamstown, MABA06/1999History; Biology
University of Pennsylvania School of Medicine, Philadelphia, PAMD05/2006Medicine
Harvard T.H. Chan School of Public Health, Boston, MAMSc05/2015Epidemiology

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K01HL123349 (HYLE, EMILY PARKER) Jan 15, 2016 - Dec 31, 2020
    Cardiovascular Disease in South African HIV Patients: Value of Prevention
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hyle EP, Scott JA, Sax PE, Millham LRI, Dugdale CM, Weinstein MC, Freedberg KA, Walensky RP. Clinical Impact and Cost-effectiveness of Genotype Testing at Human Immunodeficiency Virus Diagnosis in the United States. Clin Infect Dis. 2020 Mar 17; 70(7):1353-1363. PMID: 31055599.
  2. McCann NC, Horn TH, Hyle EP, Walensky RP. HIV Antiretroviral Therapy Costs in the United States, 2012-2018. JAMA Intern Med. 2020 Feb 03. PMID: 32011622.
  3. Flash MJE, Garland WH, Martey EB, Schackman BR, Oksuzyan S, Scott JA, Jeng PJ, Rubio M, Losina E, Freedberg KA, Kulkarni SP, Hyle EP. Cost-effectiveness of a Medical Care Coordination Program for People With HIV in Los Angeles County. Open Forum Infect Dis. 2019 Dec; 6(12):ofz537. PMID: 31909083.
  4. Hyle EP, Rao SR, Bangs AC, Gastañaduy P, Fiebelkorn AP, Hagmann SHF, Walker AT, Walensky RP, Ryan ET, LaRocque RC. Clinical Practices for Measles-Mumps-Rubella Vaccination Among US Pediatric International Travelers. JAMA Pediatr. 2019 Dec 09; e194515. PMID: 31816033.
  5. Dugdale CM, Phillips TK, Myer L, Hyle EP, Brittain K, Freedberg KA, Cunnama L, Walensky RP, Zerbe A, Weinstein MC, Abrams EJ, Ciaranello AL. Cost-effectiveness of integrating postpartum antiretroviral therapy and infant care into maternal & child health services in South Africa. PLoS One. 2019; 14(11):e0225104. PMID: 31730630.
  6. Hyle EP, Fields NF, Fiebelkorn AP, Walker AT, Gastañaduy P, Rao SR, Ryan ET, LaRocque RC, Walensky RP. The Clinical Impact and Cost-effectiveness of Measles-Mumps-Rubella Vaccination to Prevent Measles Importations Among International Travelers From the United States. Clin Infect Dis. 2019 07 02; 69(2):306-315. PMID: 30312374.
    Citations:    Fields:    
  7. Hyle EP, Bekker LG, Martey EB, Huang M, Xu A, Parker RA, Walensky RP, Middelkoop K. Cardiovascular risk factors among ART-experienced people with HIV in South Africa. J Int AIDS Soc. 2019 04; 22(4):e25274. PMID: 30990252.
  8. Brown-Elliott BA, Simmer PJ, Trovato A, Hyle EP, Droz S, Buckwalter SP, Borroni E, Branda JA, Iana E, Mariottini A, Nelson J, Matteelli A, Toney NC, Scarparo C, de Man TJB, Vasireddy R, Gandhi RT, Wengenack NL, Cirillo DM, Wallace RJ, Tortoli E. Mycobacterium decipiens sp. nov., a new species closely related to the Mycobacterium tuberculosis complex. Int J Syst Evol Microbiol. 2018 Nov; 68(11):3557-3562. PMID: 30204586.
    Citations:    Fields:    Translation:HumansCells
  9. Paras ML, Hyle EP, Foreman RK, Coffey KC. Case 14-2018: A 68-Year-Old Woman with a Rash, Hyponatremia, and Uveitis. N Engl J Med. 2018 May 10; 378(19):1825-1833. PMID: 29742372.
    Citations:    Fields:    Translation:HumansCells
  10. Piantadosi A, Kanjilal S, Ganesh V, Khanna A, Hyle EP, Rosand J, Bold T, Metsky HC, Lemieux J, Leone MJ, Freimark L, Matranga CB, Adams G, McGrath G, Zamirpour S, Telford S, Rosenberg E, Cho T, Frosch MP, Goldberg MB, Mukerji SS, Sabeti PC. Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing. Clin Infect Dis. 2018 02 10; 66(5):789-792. PMID: 29020227.
    Citations: 1     Fields:    
  11. Hyle EP, Mayosi BM, Middelkoop K, Mosepele M, Martey EB, Walensky RP, Bekker LG, Triant VA. The association between HIV and atherosclerotic cardiovascular disease in sub-Saharan Africa: a systematic review. BMC Public Health. 2017 Dec 15; 17(1):954. PMID: 29246206.
    Citations:    Fields:    Translation:Humans
  12. Murray EJ, Robins JM, Seage GR, Lodi S, Hyle EP, Reddy KP, Freedberg KA, Hernán MA. Using Observational Data to Calibrate Simulation Models. Med Decis Making. 2018 02; 38(2):212-224. PMID: 29141153.
    Citations:    Fields:    
  13. Reddy KP, Kong CY, Hyle EP, Baggett TP, Huang M, Parker RA, Paltiel AD, Losina E, Weinstein MC, Freedberg KA, Walensky RP. Lung Cancer Mortality Associated With Smoking and Smoking Cessation Among People Living With HIV in the United States. JAMA Intern Med. 2017 11 01; 177(11):1613-1621. PMID: 28975270.
    Citations: 5     Fields:    Translation:Humans
  14. Borre ED, Hyle EP, Paltiel AD, Neilan AM, Sax PE, Freedberg KA, Weinstein MC, Walensky RP. The Clinical and Economic Impact of Attaining National HIV/AIDS Strategy Treatment Targets in the United States. J Infect Dis. 2017 10 17; 216(7):798-807. PMID: 29029344.
    Citations:    Fields:    Translation:Humans
  15. Koullias Y, Sax PE, Fields NF, Walensky RP, Hyle EP. Should We Be Testing for Baseline Integrase Resistance in Patients Newly Diagnosed With Human Immunodeficiency Virus? Clin Infect Dis. 2017 10 15; 65(8):1274-1281. PMID: 28605418.
    Citations: 1     Fields:    Translation:HumansCells
  16. Losina E, Hyle EP, Borre ED, Linas BP, Sax PE, Weinstein MC, Rusu C, Ciaranello AL, Walensky RP, Freedberg KA. Projecting 10-year, 20-year, and Lifetime Risks of Cardiovascular Disease in Persons Living With Human Immunodeficiency Virus in the United States. Clin Infect Dis. 2017 10 15; 65(8):1266-1271. PMID: 28605504.
    Citations: 8     Fields:    Translation:Humans
  17. Hyle EP, Jani IV, Rosettie KL, Wood R, Osher B, Resch S, Pei PP, Maggiore P, Freedberg KA, Peter T, Parker RA, Walensky RP. The value of point-of-care CD4+ and laboratory viral load in tailoring antiretroviral therapy monitoring strategies to resource limitations. AIDS. 2017 09 24; 31(15):2135-2145. PMID: 28906279.
    Citations:    Fields:    Translation:Humans
  18. Walensky RP, Borre ED, Bekker LG, Hyle EP, Gonsalves GS, Wood R, Eholié SP, Weinstein MC, Anglaret X, Freedberg KA, Paltiel AD. Do Less Harm: Evaluating HIV Programmatic Alternatives in Response to Cutbacks in Foreign Aid. Ann Intern Med. 2017 Nov 07; 167(9):618-629. PMID: 28847013.
    Citations: 2     Fields:    Translation:Humans
  19. Chu JT, Hossain R, Silverblatt FJ, Hyle EP, Turbett SE. Case 22-2017. A 21-Year-Old Woman with Fever, Headache, and Myalgias. N Engl J Med. 2017 07 20; 377(3):268-278. PMID: 28723324.
    Citations:    Fields:    Translation:Humans
  20. Hyle EP, Jani IV, Rosettie KL, Wood R, Osher B, Resch S, Pei PP, Maggiore P, Freedberg KA, Peter T, Parker RA, Walensky RP. The value of point-of-Care CD4 and Laboratory viral Load in tailoring ART monitoring Strategies to resource limitations. AIDS. 2017 Jul 07. PMID: 28692541.
  21. Hyle EP, Rao SR, Jentes ES, Parker Fiebelkorn A, Hagmann SHF, Taylor Walker A, Walensky RP, Ryan ET, LaRocque RC. Missed Opportunities for Measles, Mumps, Rubella Vaccination Among Departing U.S. Adult Travelers Receiving Pretravel Health Consultations. Ann Intern Med. 2017 07 18; 167(2):77-84. PMID: 28505632.
    Citations:    Fields:    Translation:HumansPHPublic Health
  22. Walensky RP, Borre ED, Bekker LG, Resch SC, Hyle EP, Wood R, Weinstein MC, Ciaranello AL, Freedberg KA, Paltiel AD. The Anticipated Clinical and Economic Effects of 90-90-90 in South Africa. Ann Intern Med. 2016 09 06; 165(5):325-33. PMID: 27240120.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  23. Ehrlichman LK, Kadzielski JJ, Hyle EP, Jupiter JB. Nontuberculous Mycobacterial Osteomyelitis of the Thumb: Successful Treatment with Serial Debridement, Antimicrobial Therapy, External Fixation, and Interphalangeal Arthrodesis: A Case Report. JBJS Case Connect. 2015 Oct-Dec; 5(4):e87. PMID: 29252794.
    Citations:    Fields:    
  24. Hyle EP, Alame D. Case records of the Massachusetts General Hospital. Case 13-2015. A 27-year-old woman with arthralgias and a rash. N Engl J Med. 2015 Apr 23; 372(17):1657-64. PMID: 25901430.
    Citations:    Fields:    Translation:Humans
  25. Hyle EP, Shepard JA. Case 23-2014: Fevers, rash, pancytopenia, and abnormal liver function. N Engl J Med. 2014 10 23; 371(17):1654. PMID: 25337762.
    Citations:    Fields:    Translation:Humans
  26. Simner PJ, Hyle EP, Buckwalter SP, Branda JA, Brown-Elliott BA, Franklin J, Toney NC, de Man TJ, Wallace RJ, Vasireddy R, Gandhi RT, Wengenack NL. Tenosynovitis caused by a novel nontuberculous Mycobacterium species initially misidentified as a member of the Mycobacterium tuberculosis complex. J Clin Microbiol. 2014 Dec; 52(12):4414-8. PMID: 25253791.
    Citations: 1     Fields:    Translation:HumansCells
  27. Hyle EP, Jani IV, Lehe J, Su AE, Wood R, Quevedo J, Losina E, Bassett IV, Pei PP, Paltiel AD, Resch S, Freedberg KA, Peter T, Walensky RP. The clinical and economic impact of point-of-care CD4 testing in mozambique and other resource-limited settings: a cost-effectiveness analysis. PLoS Med. 2014 Sep; 11(9):e1001725. PMID: 25225800.
    Citations: 24     Fields:    Translation:Humans
  28. Hyle EP, Naidoo K, Su AE, El-Sadr WM, Freedberg KA. HIV, tuberculosis, and noncommunicable diseases: what is known about the costs, effects, and cost-effectiveness of integrated care? J Acquir Immune Defic Syndr. 2014 Sep 01; 67 Suppl 1:S87-95. PMID: 25117965.
    Citations: 13     Fields:    Translation:Humans
  29. Hay CM, Shepard JA, Hyle EP, Duncan LM. Case records of the Massachusetts General Hospital. Case 23-2014. A 41-year-old man with fevers, rash, pancytopenia, and abnormal liver function. N Engl J Med. 2014 Jul 24; 371(4):358-66. PMID: 25054720.
    Citations:    Fields:    Translation:Humans
  30. Bassett IV, Govindasamy D, Erlwanger AS, Hyle EP, Kranzer K, van Schaik N, Noubary F, Paltiel AD, Wood R, Walensky RP, Losina E, Bekker LG, Freedberg KA. Mobile HIV screening in Cape Town, South Africa: clinical impact, cost and cost-effectiveness. PLoS One. 2014; 9(1):e85197. PMID: 24465503.
    Citations: 19     Fields:    Translation:HumansPHPublic Health
  31. Drain PK, Hyle EP, Noubary F, Freedberg KA, Wilson D, Bishai WR, Rodriguez W, Bassett IV. Diagnostic point-of-care tests in resource-limited settings. Lancet Infect Dis. 2014 Mar; 14(3):239-49. PMID: 24332389.
    Citations: 55     Fields:    Translation:Humans
  32. Hyle EP, Sax PE, Walensky RP. Potential savings by reduced CD4 monitoring in stable patients with HIV receiving antiretroviral therapy. JAMA Intern Med. 2013 Oct 14; 173(18):1746-8. PMID: 23978894.
    Citations: 11     Fields:    Translation:Humans
  33. Hyle EP, Wood BR, Backman ES, Noubary F, Hwang J, Lu Z, Losina E, Walensky RP, Gandhi RT. High frequency of hypothalamic-pituitary-adrenal axis dysfunction after local corticosteroid injection in HIV-infected patients on protease inhibitor therapy. J Acquir Immune Defic Syndr. 2013 Aug 15; 63(5):602-8. PMID: 23714741.
    Citations: 2     Fields:    Translation:Humans
  34. Hyle EP, Shu B, Lindstrom S, Klimov A, Hancock K, Ferraro MJ, Traum AZ, Michelow IC. A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection. Pediatr Transplant. 2012 Aug; 16(5):E158-61. PMID: 21429059.
    Citations:    Fields:    Translation:HumansCells
  35. Hyle EP, Ferraro MJ, Silver M, Lee H, Hooper DC. Ertapenem-resistant Enterobacteriaceae: risk factors for acquisition and outcomes. Infect Control Hosp Epidemiol. 2010 Dec; 31(12):1242-9. PMID: 21029005.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  36. Refaat M, Hyle E, Malhotra R, Seidman D, Dey B. Linezolid-induced lingua villosa nigra. Am J Med. 2008 Jun; 121(6):e1. PMID: 18501207.
    Citations: 2     Fields:    Translation:Humans
  37. Hyle EP, Gasink LB, Linkin DR, Bilker WB, Lautenbach E. Use of different thresholds of prior antimicrobial use in defining exposure: impact on the association between antimicrobial use and antimicrobial resistance. J Infect. 2007 Nov; 55(5):414-8. PMID: 17850877.
    Citations: 5     Fields:    Translation:HumansCells
  38. Hyle EP, Bilker WB, Gasink LB, Lautenbach E. Impact of different methods for describing the extent of prior antibiotic exposure on the association between antibiotic use and antibiotic-resistant infection. Infect Control Hosp Epidemiol. 2007 Jun; 28(6):647-54. PMID: 17520535.
    Citations: 5     Fields:    Translation:HumansCells
  39. Lipworth AD, Hyle EP, Fishman NO, Nachamkin I, Bilker WB, Marr AM, Larosa LA, Kasbekar N, Lautenbach E. Limiting the emergence of extended-spectrum Beta-lactamase-producing enterobacteriaceae: influence of patient population characteristics on the response to antimicrobial formulary interventions. Infect Control Hosp Epidemiol. 2006 Mar; 27(3):279-86. PMID: 16532416.
    Citations: 13     Fields:    Translation:HumansCells
  40. Hyle EP, Lipworth AD, Zaoutis TE, Nachamkin I, Bilker WB, Lautenbach E. Impact of inadequate initial antimicrobial therapy on mortality in infections due to extended-spectrum beta-lactamase-producing enterobacteriaceae: variability by site of infection. Arch Intern Med. 2005 Jun 27; 165(12):1375-80. PMID: 15983286.
    Citations: 40     Fields:    Translation:HumansCells
  41. Hyle EP, Lipworth AD, Zaoutis TE, Nachamkin I, Fishman NO, Bilker WB, Mao X, Lautenbach E. Risk factors for increasing multidrug resistance among extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species. Clin Infect Dis. 2005 May 01; 40(9):1317-24. PMID: 15825035.
    Citations: 24     Fields:    Translation:HumansCells
  42. Warren MP, Brooks-Gunn J, Fox RP, Holderness CC, Hyle EP, Hamilton WG, Hamilton L. Persistent osteopenia in ballet dancers with amenorrhea and delayed menarche despite hormone therapy: a longitudinal study. Fertil Steril. 2003 Aug; 80(2):398-404. PMID: 12909505.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  43. Warren MP, Brooks-Gunn J, Fox RP, Holderness CC, Hyle EP, Hamilton WG. Osteopenia in exercise-associated amenorrhea using ballet dancers as a model: a longitudinal study. J Clin Endocrinol Metab. 2002 Jul; 87(7):3162-8. PMID: 12107218.
    Citations: 41     Fields:    Translation:Humans
  44. Warren MP, Voussoughian F, Geer EB, Hyle EP, Adberg CL, Ramos RH. Functional hypothalamic amenorrhea: hypoleptinemia and disordered eating. J Clin Endocrinol Metab. 1999 Mar; 84(3):873-7. PMID: 10084564.
    Citations: 33     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.