Title Associate Professor of Anaesthesia Institution Beth Israel Deaconess Medical Center Address Beth Israel Deaconess Medical Center Anesthesia & Critical Care, DA 717 330 Brookline Ave Boston MA 02215
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Research
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1R21NS130561-01
(Levy Dan)
Sep 1, 2022 - Aug 31, 2024
Meningeal Nociceptor-Immune Signaling in Migraine
Role Description: This proposal explores a peripheral neuroimmune mechanism of migraine, involving bidirectional communication between meningeal nociceptors and meningeal immune cells that drives migraine headache. If successful, the project could provide a dramatically better understanding of the role of neurogenic inflammation in migraine pathophysiology and serve as an experimental foundation for future explorations of mechanistic insights into meningeal neuroimmune crosstalk and further testing of specific immune cells and related proinflammatory mediators as potential therapeutic targets for migraine pain.
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R01NS115972
(LEVY, DAN)
Dec 15, 2020 - Nov 30, 2025
Cortical-meningeal interactions underlying migraine headache
Role: Principal Investigator
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2R01NS078263-05
(Dan Levy)
Sep 1, 2018 - May 31, 2023
MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS
Role: Principal Investigator
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R21NS101405
(LEVY, DAN)
Apr 1, 2017 - Mar 31, 2020
Chronic two-photon calcium imaging of intracranial meningeal afferents in awake behaving mice
Role: Principal Investigator
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R01NS086830
(LEVY, DAN)
Aug 15, 2014 - May 31, 2020
Peripheral Mechanisms of Posttraumatic Headache
Role: Principal Investigator
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R01NS078263
(LEVY, DAN)
Jul 15, 2013 - May 31, 2024
MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS
Role: Principal Investigator
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R21AA020305
(LEVY, DAN)
Feb 10, 2012 - Jan 31, 2015
Mechanisms of Alcohol Hangover Headache
Role: Principal Investigator
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R21NS077882
(LEVY, DAN)
Sep 1, 2011 - Aug 31, 2014
Calvarial periosteal afferents in post-traumatic headache
Role: Principal Investigator
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R21NS061116
(LEVY, DAN)
Mar 1, 2009 - Feb 28, 2012
Estrogen Withdrawal and Dural Mast Cells: Implication for Menstrual Migraine
Role: Principal Investigator
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R01NS046502
(LEVY, DAN)
Apr 1, 2004 - Mar 31, 2010
Mast Cells: Role in the Pathophysiology of Headache
Role: Principal Investigator

Bibliographic
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