Harvard Catalyst Profiles

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Gordon Campbell Weir, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U42RR016606 (WEIR, GORDON CAMPBELL) Sep 30, 2001 - Aug 31, 2007
    NIH/NCRR
    HUMAN PANCREATIC ISLET CELL RESOURCE
    Role: Principal Investigator
  2. U19DK061251 (HABENER, JOEL F) Sep 30, 2001 - Jul 31, 2007
    NIH/NIDDK
    Program Project,Restoration of Endocrine Pancreas Funct*
    Role: Co-Principal Investigator
  3. P01DK053087 (WEIR, GORDON CAMPBELL) Feb 15, 1998 - Nov 30, 2003
    NIH/NIDDK
    ISLET XENOTRANSPLANTATION--GENETIC APPROACHES TO PROBLEM
    Role: Principal Investigator
  4. R01DK050657 (WEIR, GORDON CAMPBELL) Feb 10, 1996 - Mar 31, 2008
    NIH/NIDDK
    Islet Transplantation - Protection by Immunobarriers
    Role: Principal Investigator
  5. P30DK036836 (KING, GEORGE L) Sep 30, 1986 - Mar 31, 2022
    NIH/NIDDK
    Diabetes Research Center
    Role: Co-Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Islet Isolation Core (JDC) - Core services (2)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mahmoud AI, Galdos FX, Dinan KA, Jedrychowski MP, Davis JC, Vujic A, Rachmin I, Shigley C, Pancoast JR, Lee S, Hollister-Lock J, MacGillivray CM, Gygi SP, Melton DA, Weir GC, Lee RT. Apolipoprotein E is a pancreatic extracellular factor that maintains mature ß-cell gene expression. PLoS One. 2018; 13(10):e0204595. PMID: 30303984.
    Citations:    Fields:    
  2. Hwa AJ, Weir GC. Transplantation of Macroencapsulated Insulin-Producing Cells. Curr Diab Rep. 2018 Jun 16; 18(8):50. PMID: 29909496.
    Citations: 1     Fields:    
  3. Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB. Alpha-1 antitrypsin treatment of new-onset type 1 diabetes: An open-label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics. Pediatr Diabetes. 2018 08; 19(5):945-954. PMID: 29473705.
    Citations: 1     Fields:    
  4. Evron Y, Colton CK, Ludwig B, Weir GC, Zimermann B, Maimon S, Neufeld T, Shalev N, Goldman T, Leon A, Yavriyants K, Shabtay N, Rozenshtein T, Azarov D, DiIenno AR, Steffen A, de Vos P, Bornstein SR, Barkai U, Rotem A. Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply. Sci Rep. 2018 Apr 25; 8(1):6508. PMID: 29695723.
    Citations:    Fields:    
  5. Aguayo-Mazzucato C, van Haaren M, Mruk M, Lee TB, Crawford C, Hollister-Lock J, Sullivan BA, Johnson JW, Ebrahimi A, Dreyfuss JM, Van Deursen J, Weir GC, Bonner-Weir S. ß Cell Aging Markers Have Heterogeneous Distribution and Are Induced by Insulin Resistance. Cell Metab. 2017 Apr 04; 25(4):898-910.e5. PMID: 28380379.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  6. Ebrahimi A, Jung MH, Dreyfuss JM, Pan H, Sgroi D, Bonner-Weir S, Weir GC. Evidence of stress in ß cells obtained with laser capture microdissection from pancreases of brain dead donors. Islets. 2017 03 04; 9(2):19-29. PMID: 28252345.
    Citations: 1     Fields:    Translation:HumansCells
  7. Weir GC, Bonner-Weir S. Glucose Driven Changes in Beta Cell Identity Are Important for Function and Possibly Autoimmune Vulnerability during the Progression of Type 1 Diabetes. Front Genet. 2017; 8:2. PMID: 28174593.
    Citations: 1     
  8. Weir GC, Bonner-Weir S. GABA Signaling Stimulates ß Cell Regeneration in Diabetic Mice. Cell. 2017 01 12; 168(1-2):7-9. PMID: 28086099.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang BC, Yang XW, Weir GC, Langer R, Anderson DG. Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid-Glucose Complexation. Langmuir. 2016 08 30; 32(34):8743-7. PMID: 27455412.
    Citations: 7     Fields:    Translation:Cells
  10. Shankar SS, Vella A, Raymond RH, Staten MA, Calle RA, Bergman RN, Cao C, Chen D, Cobelli C, Dalla Man C, Deeg M, Dong JQ, Lee DS, Polidori D, Robertson RP, Ruetten H, Stefanovski D, Vassileva MT, Weir GC, Fryburg DA. Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of ß-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series. Diabetes Care. 2016 09; 39(9):1602-13. PMID: 27407117.
    Citations: 6     Fields:    Translation:HumansCells
  11. Markmann JF, Bartlett ST, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, O'Connell PJ, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Khovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of ß-Cell Replacement. Transplantation. 2016 Jul; 100(7):e25-31. PMID: 27082827.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  12. Vegas AJ, Veiseh O, Doloff JC, Ma M, Tam HH, Bratlie K, Li J, Bader AR, Langan E, Olejnik K, Fenton P, Kang JW, Hollister-Locke J, Bochenek MA, Chiu A, Siebert S, Tang K, Jhunjhunwala S, Aresta-Dasilva S, Dholakia N, Thakrar R, Vietti T, Chen M, Cohen J, Siniakowicz K, Qi M, McGarrigle J, Lyle S, Harlan DM, Greiner DL, Oberholzer J, Weir GC, Langer R, Anderson DG. Corrigendum: Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates. Nat Biotechnol. 2016 06 09; 34(6):666. PMID: 27281428.
    Citations: 1     Fields:    
  13. Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG. Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nat Med. 2016 Apr; 22(4):446. PMID: 27050590.
    Citations: 2     Fields:    
  14. Bonner-Weir S, Aguayo-Mazzucato C, Weir GC. Dynamic development of the pancreas from birth to adulthood. Ups J Med Sci. 2016 May; 121(2):155-8. PMID: 26998806.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  15. Kuznetsova A, Yu Y, Hollister-Lock J, Opare-Addo L, Rozzo A, Sadagurski M, Norquay L, Reed JE, El Khattabi I, Bonner-Weir S, Weir GC, Sharma A, White MF. Trimeprazine increases IRS2 in human islets and promotes pancreatic ß cell growth and function in mice. JCI Insight. 2016; 1(3). PMID: 27152363.
    Citations: 1     Fields:    
  16. Molven A, Hollister-Lock J, Hu J, Martinez R, Njølstad PR, Liew CW, Weir G, Kulkarni RN. The Hypoglycemic Phenotype Is Islet Cell-Autonomous in Short-Chain Hydroxyacyl-CoA Dehydrogenase-Deficient Mice. Diabetes. 2016 06; 65(6):1672-8. PMID: 26953163.
    Citations:    Fields:    Translation:AnimalsCells
  17. Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, O'Connell P, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Kovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Report from IPITA-TTS Opinion Leaders Meeting on the Future of ß-Cell Replacement. Transplantation. 2016 Feb; 100 Suppl 2:S1-44. PMID: 26840096; PMCID: PMC4741413.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  18. Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliu