Harvard Catalyst Profiles

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Vladimir Vinarsky, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08HL124298 (VINARSKY, VLADIMIR) Sep 1, 2014 - Nov 30, 2019
    Re-establishment of directional mucociliary transport after epithelial injury
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Pagliari S, Vinarsky V, Martino F, Perestrelo AR, Oliver De La Cruz J, Caluori G, Vrbsky J, Mozetic P, Pompeiano A, Zancla A, Ranjani SG, Skladal P, Kytyr D, Zdráhal Z, Grassi G, Sampaolesi M, Rainer A, Forte G. YAP-TEAD1 control of cytoskeleton dynamics and intracellular tension guides human pluripotent stem cell mesoderm specification. Cell Death Differ. 2021 Apr; 28(4):1193-1207. PMID: 33116297.
    Citations: 2     Fields:    
  2. Perestrelo AR, Silva AC, Oliver-De La Cruz J, Martino F, Horváth V, Caluori G, Polanský O, Vinarský V, Azzato G, de Marco G, Žampachová V, Skládal P, Pagliari S, Rainer A, Pinto-do-Ó P, Caravella A, Koci K, Nascimento DS, Forte G. Multiscale Analysis of Extracellular Matrix Remodeling in the Failing Heart. Circ Res. 2021 01 08; 128(1):24-38. PMID: 33106094.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  3. Hariri LP, North CM, Shih AR, Israel RA, Maley JH, Villalba JA, Vinarsky V, Rubin J, Okin DA, Sclafani A, Alladina JW, Griffith JW, Gillette MA, Raz Y, Richards CJ, Wong AK, Ly A, Hung YP, Chivukula RR, Petri CR, Calhoun TF, Brenner LN, Hibbert KA, Medoff BD, Hardin CC, Stone JR, Mino-Kenudson M. Lung Histopathology in Coronavirus Disease 2019 as Compared With Severe Acute Respiratory Sydrome and H1N1 Influenza: A Systematic Review. Chest. 2021 01; 159(1):73-84. PMID: 33038391.
    Citations: 27     Fields:    Translation:HumansCells
  4. Petri CR, Brenner LN, Calhoun TF, Chivukula RR, Maley JH, Vinarsky V, Dudzinski DM, Hardin CC. The Fast Literature Assessment and Review (FLARE) Initiative. A Collaborative Effort for Timely Literature Appraisal during the Coronavirus Disease Pandemic. ATS Sch. 2020 Jun 29; 1(2):186-193. PMID: 33870283.
    Citations: 3     
  5. Maley JH, Petri CR, Brenner LN, Chivukula RR, Calhoun TF, Vinarsky V, Hardin CC. Anticoagulation, immortality, and observations of COVID-19. Res Pract Thromb Haemost. 2020 Jul; 4(5):674-676. PMID: 32685874.
    Citations: 1     
  6. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. Author Correction: A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020 Feb; 26(2):300. PMID: 31996837.
    Citations: 2     Fields:    
  7. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020 02; 26(2):244-251. PMID: 31959991.
    Citations: 8     Fields:    Translation:HumansCells
  8. Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. Nature. 2018 08; 560(7718):319-324. PMID: 30069044.
    Citations: 215     Fields:    Translation:HumansAnimalsCells
  9. Garlíková Z, Silva AC, Rabata A, Potešil D, Ihnatová I, Dumková J, Koledová Z, Zdráhal Z, Vinarský V, Hampl A, Pinto-do-Ó P, Nascimento DS. Generation of a Close-to-Native In Vitro System to Study Lung Cells-Extracellular Matrix Crosstalk. Tissue Eng Part C Methods. 2018 01; 24(1):1-13. PMID: 28895470.
    Citations: 2     Fields:    Translation:AnimalsCells
  10. Bagherpoor AJ, Dolezalova D, Barta T, Kucírek M, Sani SA, Ešner M, Kunova Bosakova M, Vinarský V, Peskova L, Hampl A, Štros M. Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins. Stem Cells Dev. 2017 03 01; 26(5):328-340. PMID: 27863459.
    Citations: 5     Fields:    Translation:HumansCells
  11. Mou H, Vinarsky V, Tata PR, Brazauskas K, Choi SH, Crooke AK, Zhang B, Solomon GM, Turner B, Bihler H, Harrington J, Lapey A, Channick C, Keyes C, Freund A, Artandi S, Mense M, Rowe S, Engelhardt JF, Hsu YC, Rajagopal J. Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells. Cell Stem Cell. 2016 08 04; 19(2):217-231. PMID: 27320041.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  12. Dowdall JR, Sadow PM, Hartnick C, Vinarsky V, Mou H, Zhao R, Song PC, Franco RA, Rajagopal J. Identification of distinct layers within the stratified squamous epithelium of the adult human true vocal fold. Laryngoscope. 2015 Sep; 125(9):E313-9. PMID: 25988619.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  13. Zhao R, Fallon TR, Saladi SV, Pardo-Saganta A, Villoria J, Mou H, Vinarsky V, Gonzalez-Celeiro M, Nunna N, Hariri LP, Camargo F, Ellisen LW, Rajagopal J. Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells. Dev Cell. 2014 Jul 28; 30(2):151-65. PMID: 25043474.
    Citations: 74     Fields:    Translation:AnimalsCells
  14. Tata PR, Pardo-Saganta A, Prabhu M, Vinarsky V, Law BM, Fontaine BA, Tager AM, Rajagopal J. Airway-specific inducible transgene expression using aerosolized doxycycline. Am J Respir Cell Mol Biol. 2013 Dec; 49(6):1048-56. PMID: 23848320.
    Citations: 6     Fields:    Translation:AnimalsCells
  15. Tata PR, Mou H, Pardo-Saganta A, Zhao R, Prabhu M, Law BM, Vinarsky V, Cho JL, Breton S, Sahay A, Medoff BD, Rajagopal J. Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature. 2013 Nov 14; 503(7475):218-23. PMID: 24196716.
    Citations: 236     Fields:    Translation:AnimalsCells
  16. Vinarsky V, Krivanek J, Rankel L, Nahacka Z, Barta T, Jaros J, Andera L, Hampl A. Human embryonic and induced pluripotent stem cells express TRAIL receptors and can be sensitized to TRAIL-induced apoptosis. Stem Cells Dev. 2013 Nov 15; 22(22):2964-74. PMID: 23806100.
    Citations: 5     Fields:    Translation:HumansCells
  17. Pardo-Saganta A, Law BM, Gonzalez-Celeiro M, Vinarsky V, Rajagopal J. Ciliated cells of pseudostratified airway epithelium do not become mucous cells after ovalbumin challenge. Am J Respir Cell Mol Biol. 2013 Mar; 48(3):364-73. PMID: 23239495.
    Citations: 28     Fields:    Translation:AnimalsCells
  18. Kim JK, Vinarsky V, Wain J, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH. In vivo imaging of tracheal epithelial cells in mice during airway regeneration. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):864-8. PMID: 22984086.
    Citations: 17     Fields:    Translation:AnimalsCells
  19. Dolezalova D, Mraz M, Barta T, Plevova K, Vinarsky V, Holubcova Z, Jaros J, Dvorak P, Pospisilova S, Hampl A. MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. Stem Cells. 2012 Jul; 30(7):1362-72. PMID: 22511267.
    Citations: 50     Fields:    Translation:HumansCells
  20. Vinarsky V, Fine RL, Assaad A, Qian Y, Chabot JA, Su GH, Frucht H. Head and neck squamous cell carcinoma in FAMMM syndrome. Head Neck. 2009 Nov; 31(11):1524-7. PMID: 19360740.
    Citations: 13     Fields:    Translation:Humans
  21. Stevenson TJ, Vinarsky V, Atkinson DL, Keating MT, Odelberg SJ. Tissue inhibitor of metalloproteinase 1 regulates matrix metalloproteinase activity during newt limb regeneration. Dev Dyn. 2006 Mar; 235(3):606-16. PMID: 16372340.
    Citations: 11     Fields:    Translation:AnimalsCells
  22. Vinarsky V, Atkinson DL, Stevenson TJ, Keating MT, Odelberg SJ. Normal newt limb regeneration requires matrix metalloproteinase function. Dev Biol. 2005 Mar 01; 279(1):86-98. PMID: 15708560.
    Citations: 69     Fields:    Translation:AnimalsCells
  23. Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):1870-5. PMID: 11854487.
    Citations: 68     Fields:    Translation:AnimalsCells
  24. Hagen TM, Vinarsky V, Wehr CM, Ames BN. (R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo. Antioxid Redox Signal. 2000; 2(3):473-83. PMID: 11229361.
    Citations: 26     Fields:    Translation:AnimalsCells
  25. Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J. 1999 Feb; 13(2):411-8. PMID: 9973329.
    Citations: 48     Fields:    Translation:AnimalsCells
  26. Lykkesfeldt J, Hagen TM, Vinarsky V, Ames BN. Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation. FASEB J. 1998 Sep; 12(12):1183-9. PMID: 9737721.
    Citations: 20     Fields:    Translation:AnimalsCells
  27. Hagen TM, Ingersoll RT, Wehr CM, Lykkesfeldt J, Vinarsky V, Bartholomew JC, Song MH, Ames BN. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9562-6. PMID: 9689120.
    Citations: 63     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.