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Thomas Francis Serwold, PH.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. S10OD021740 (SERWOLD, THOMAS F) May 1, 2016 - Apr 30, 2017
    NIH
    Special BD LSRFortessa
    Role: Principal Investigator
  2. F32AI058521 (SERWOLD, THOMAS F) Mar 16, 2005 - Mar 15, 2007
    NIH/NIAID
    Factors that modulate thymic output
    Role: Principal Investigator
  3. P30DK036836 (KING, GEORGE L) Sep 30, 1986 - Mar 31, 2022
    NIH/NIDDK
    Diabetes Research Center
    Role: Co-Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Flow Cytometry Core (JDC) - Core services (14), Instruments (12) and Software (2)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kim MJ, Serwold T. Isolation of Highly Viable Thymic Epithelial Cells for Use in In Vitro and In Vivo Experiments. Methods Mol Biol. 2019; 1899:143-156. PMID: 30649771.
    Citations:    Fields:    
  2. Spidale NA, Sylvia K, Narayan K, Miu B, Frascoli M, Melichar HJ, Zhihao W, Kisielow J, Palin A, Serwold T, Love P, Kobayashi M, Yoshimoto M, Jain N, Kang J. Interleukin-17-Producing ?d T Cells Originate from SOX13+ Progenitors that Are Independent of ?dTCR Signaling. Immunity. 2018 Nov 20; 49(5):857-872.e5. PMID: 30413363.
    Citations:    Fields:    
  3. Karimzadeh A, Scarfone VM, Varady E, Chao C, Grathwohl K, Fathman JW, Fruman DA, Serwold T, Inlay MA. The CD11a and Endothelial Protein C Receptor Marker Combination Simplifies and Improves the Purification of Mouse Hematopoietic Stem Cells. Stem Cells Transl Med. 2018 Jun; 7(6):468-476. PMID: 29543389.
    Citations:    Fields:    
  4. Thelin MA, Kissler S, Vigneault F, Watters AL, White D, Koshy ST, Vermillion SA, Mooney DJ, Serwold T, Ali OA. In Vivo Enrichment of Diabetogenic T Cells. Diabetes. 2017 08; 66(8):2220-2229. PMID: 28396510.
    Citations: 3     Fields:    Translation:AnimalsCells
  5. Schuster C, Gerold KD, Schober K, Probst L, Boerner K, Kim MJ, Ruckdeschel A, Serwold T, Kissler S. The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. Immunity. 2015 May 19; 42(5):942-52. PMID: 25979422; PMCID: PMC4439257.
    Citations: 14     Fields:    Translation:AnimalsCells
  6. Vazquez SE, Inlay MA, Serwold T. CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1. Exp Hematol. 2015 Jul; 43(7):578-85. PMID: 25892186; PMCID: PMC4480781.
    Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
  7. Kim MJ, Miller CM, Shadrach JL, Wagers AJ, Serwold T. Young, proliferative thymic epithelial cells engraft and function in aging thymuses. J Immunol. 2015 May 15; 194(10):4784-95. PMID: 25870244; PMCID: PMC4481326.
    Citations: 8     Fields:    Translation:AnimalsCells
  8. Abbey JL, Karsunky H, Serwold T, Papathanasiou P, Weissman IL, O'Neill HC. Expression of TCR-Vß peptides by murine bone marrow cells does not identify T-cell progenitors. J Cell Mol Med. 2015 Aug; 19(8):1956-64. PMID: 25754612; PMCID: PMC4549046.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Rao TN, Marks-Bluth J, Sullivan J, Gupta MK, Chandrakanthan V, Fitch SR, Ottersbach K, Jang YC, Piao X, Kulkarni RN, Serwold T, Pimanda JE, Wagers AJ. High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. Stem Cell Res. 2015 May; 14(3):307-22. PMID: 25840412; PMCID: PMC4439311.
    Citations: 3     Fields:    Translation:AnimalsCells
  10. Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ. Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science. 2014 May 09; 344(6184):649-52. PMID: 24797481; PMCID: PMC4104429.
    Citations: 181     Fields:    Translation:AnimalsCells
  11. Inlay MA, Serwold T, Mosley A, Fathman JW, Dimov IK, Seita J, Weissman IL. Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development. Stem Cell Reports. 2014 Apr 08; 2(4):457-72. PMID: 24749071; PMCID: PMC3986503.
    Citations: 18     Fields:    Translation:AnimalsCells
  12. Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 2013 Sep 15; 27(18):2063. PMID: 24065771.
    Citations:    
  13. Garfin PM, Min D, Bryson JL, Serwold T, Edris B, Blackburn CC, Richie ER, Weinberg KI, Manley NR, Sage J, Viatour P. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. J Exp Med. 2013 Jun 03; 210(6):1087-97. PMID: 23669396; PMCID: PMC3674705.
    Citations: 13     Fields:    Translation:AnimalsCells
  14. Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell. 2013 May 09; 153(4):828-39. PMID: 23663781; PMCID: PMC3677132.
    Citations: 190     Fields:    Translation:HumansAnimalsCells
  15. Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL. Gene Expression Commons: an open platform for absolute gene expression profiling. PLoS One. 2012; 7(7):e40321. PMID: 22815738; PMCID: PMC3399844.
    Citations: 83     Fields:    Translation:HumansAnimals
  16. Richie Ehrlich LI, Serwold T, Weissman IL. In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors. Blood. 2011 Mar 03; 117(9):2618-24. PMID: 21163922; PMCID: PMC3062354.
    Citations: 25     Fields:    Translation:AnimalsCells
  17. Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL. T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18939-43. PMID: 20956329; PMCID: PMC2973852.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  18. Ji H, Ehrlich LI, Seita J, Murakami P, Doi A, Lindau P, Lee H, Aryee MJ, Irizarry RA, Kim K, Rossi DJ, Inlay MA, Serwold T, Karsunky H, Ho L, Daley GQ, Weissman IL, Feinberg AP. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010 Sep 16; 467(7313):338-42. PMID: 20720541; PMCID: PMC2956609.
    Citations: 246     Fields:    Translation:AnimalsCells
  19. Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH. Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. J Immunol. 2010 Sep 15; 185(6):3564-73. PMID: 20709953; PMCID: PMC2933292.
    Citations: 11     Fields:    Translation:AnimalsCells
  20. Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 2009 Oct 15; 23(20):2376-81. PMID: 19833765; PMCID: PMC2764492.
    Citations: 106     Fields:    Translation:AnimalsCells
  21. Serwold T, Ehrlich LI, Weissman IL. Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood. 2009 Jan 22; 113(4):807-15. PMID: 18927436; PMCID: PMC4123410.
    Citations: 64     Fields:    Translation:AnimalsCells
  22. Karsunky H, Inlay MA, Serwold T, Bhattacharya D, Weissman IL. Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood. 2008 Jun 15; 111(12):5562-70. PMID: 18424665; PMCID: PMC2424154.
    Citations: 66     Fields:    Translation:AnimalsCells
  23. Serwold T, Hochedlinger K, Inlay MA, Jaenisch R, Weissman IL. Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes. J Immunol. 2007 Jul 15; 179(2):928-38. PMID: 17617584.
    Citations: 24     Fields:    Translation:AnimalsCells
  24. Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell. 2006 Jul 28; 126(2):415-26. PMID: 16873070.
    Citations: 79     Fields:    Translation:AnimalsCells
  25. Shastri N, Cardinaud S, Schwab SR, Serwold T, Kunisawa J. All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Immunol Rev. 2005 Oct; 207:31-41. PMID: 16181325.
    Citations: 30     Fields:    Translation:HumansAnimals
  26. Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature. 2002 Oct 03; 419(6906):480-3. PMID: 12368856.
    Citations: 129     Fields:    Translation:AnimalsCells
  27. Shastri N, Schwab S, Serwold T. Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules. Annu Rev Immunol. 2002; 20:463-93. PMID: 11861610.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  28. Bischof G, Serwold TF, Machen TE. Does nitric oxide regulate capacitative Ca influx in HEK 293 cells? Cell Calcium. 1997 Feb; 21(2):135-42. PMID: 9132296.
    Citations: 4     Fields:    Translation:HumansCells
  29. Stroop SD, Kuestner RE, Serwold TF, Chen L, Moore EE. Chimeric human calcitonin and glucagon receptors reveal two dissociable calcitonin interaction sites. Biochemistry. 1995 Jan 24; 34(3):1050-7. PMID: 7827020.
    Citations: 9     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.