Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Check out the new look and feel of Harvard Catalyst Profiles! Learn more on our About and Help pages.

Thomas Francis Serwold, PH.D.

Title
Institution
Department
Address
Phone
Fax

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. S10OD021740 (SERWOLD, THOMAS F) May 1, 2016 - Apr 30, 2017
    NIH
    Special BD LSRFortessa
    Role: Principal Investigator
  2. F32AI058521 (SERWOLD, THOMAS F) Mar 16, 2005 - Mar 15, 2007
    NIH/NIAID
    Factors that modulate thymic output
    Role: Principal Investigator
  3. P30DK036836 (KING, GEORGE L) Sep 30, 1986 - Mar 31, 2022
    NIH/NIDDK
    Diabetes Research Center
    Role: Co-Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Flow Cytometry Core (JDC) - Core services (14), Instruments (12) and Software (2)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Karimzadeh A, Scarfone VM, Varady E, Chao C, Grathwohl K, Fathman JW, Fruman DA, Serwold T, Inlay MA. The CD11a and Endothelial Protein C Receptor Marker Combination Simplifies and Improves the Purification of Mouse Hematopoietic Stem Cells. Stem Cells Transl Med. 2018 Jun; 7(6):468-476. PMID: 29543389.
    View in: PubMed
  2. Thelin MA, Kissler S, Vigneault F, Watters AL, White D, Koshy ST, Vermillion SA, Mooney DJ, Serwold T, Ali OA. In Vivo Enrichment of Diabetogenic T Cells. Diabetes. 2017 08; 66(8):2220-2229. PMID: 28396510.
    View in: PubMed
  3. Schuster C, Gerold KD, Schober K, Probst L, Boerner K, Kim MJ, Ruckdeschel A, Serwold T, Kissler S. The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. Immunity. 2015 May 19; 42(5):942-52. PMID: 25979422; PMCID: PMC4439257.
  4. Vazquez SE, Inlay MA, Serwold T. CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1. Exp Hematol. 2015 Jul; 43(7):578-85. PMID: 25892186; PMCID: PMC4480781.
  5. Kim MJ, Miller CM, Shadrach JL, Wagers AJ, Serwold T. Young, proliferative thymic epithelial cells engraft and function in aging thymuses. J Immunol. 2015 May 15; 194(10):4784-95. PMID: 25870244; PMCID: PMC4481326.
  6. Abbey JL, Karsunky H, Serwold T, Papathanasiou P, Weissman IL, O'Neill HC. Expression of TCR-Vß peptides by murine bone marrow cells does not identify T-cell progenitors. J Cell Mol Med. 2015 Aug; 19(8):1956-64. PMID: 25754612; PMCID: PMC4549046.
  7. Rao TN, Marks-Bluth J, Sullivan J, Gupta MK, Chandrakanthan V, Fitch SR, Ottersbach K, Jang YC, Piao X, Kulkarni RN, Serwold T, Pimanda JE, Wagers AJ. High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. Stem Cell Res. 2015 May; 14(3):307-22. PMID: 25840412; PMCID: PMC4439311.
  8. Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ. Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science. 2014 May 09; 344(6184):649-52. PMID: 24797481; PMCID: PMC4104429.
  9. Inlay MA, Serwold T, Mosley A, Fathman JW, Dimov IK, Seita J, Weissman IL. Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development. Stem Cell Reports. 2014 Apr 08; 2(4):457-72. PMID: 24749071; PMCID: PMC3986503.
  10. Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 2013 Sep 15; 27(18):2063. PMID: 24065771.
    View in: PubMed
  11. Garfin PM, Min D, Bryson JL, Serwold T, Edris B, Blackburn CC, Richie ER, Weinberg KI, Manley NR, Sage J, Viatour P. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. J Exp Med. 2013 Jun 03; 210(6):1087-97. PMID: 23669396; PMCID: PMC3674705.
  12. Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell. 2013 May 09; 153(4):828-39. PMID: 23663781; PMCID: PMC3677132.
  13. Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL. Gene Expression Commons: an open platform for absolute gene expression profiling. PLoS One. 2012; 7(7):e40321. PMID: 22815738; PMCID: PMC3399844.
  14. Richie Ehrlich LI, Serwold T, Weissman IL. In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors. Blood. 2011 Mar 03; 117(9):2618-24. PMID: 21163922; PMCID: PMC3062354.
  15. Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL. T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18939-43. PMID: 20956329; PMCID: PMC2973852.
  16. Ji H, Ehrlich LI, Seita J, Murakami P, Doi A, Lindau P, Lee H, Aryee MJ, Irizarry RA, Kim K, Rossi DJ, Inlay MA, Serwold T, Karsunky H, Ho L, Daley GQ, Weissman IL, Feinberg AP. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010 Sep 16; 467(7313):338-42. PMID: 20720541; PMCID: PMC2956609.
  17. Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH. Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. J Immunol. 2010 Sep 15; 185(6):3564-73. PMID: 20709953; PMCID: PMC2933292.
  18. Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 2009 Oct 15; 23(20):2376-81. PMID: 19833765; PMCID: PMC2764492.
  19. Serwold T, Ehrlich LI, Weissman IL. Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood. 2009 Jan 22; 113(4):807-15. PMID: 18927436; PMCID: PMC4123410.
  20. Karsunky H, Inlay MA, Serwold T, Bhattacharya D, Weissman IL. Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood. 2008 Jun 15; 111(12):5562-70. PMID: 18424665; PMCID: PMC2424154.
  21. Serwold T, Hochedlinger K, Inlay MA, Jaenisch R, Weissman IL. Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes. J Immunol. 2007 Jul 15; 179(2):928-38. PMID: 17617584.
    View in: PubMed
  22. Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell. 2006 Jul 28; 126(2):415-26. PMID: 16873070.
    View in: PubMed
  23. Shastri N, Cardinaud S, Schwab SR, Serwold T, Kunisawa J. All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Immunol Rev. 2005 Oct; 207:31-41. PMID: 16181325.
    View in: PubMed
  24. Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature. 2002 Oct 03; 419(6906):480-3. PMID: 12368856.
    View in: PubMed
  25. Shastri N, Schwab S, Serwold T. Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules. Annu Rev Immunol. 2002; 20:463-93. PMID: 11861610.
    View in: PubMed
  26. Bischof G, Serwold TF, Machen TE. Does nitric oxide regulate capacitative Ca influx in HEK 293 cells? Cell Calcium. 1997 Feb; 21(2):135-42. PMID: 9132296.
    View in: PubMed
  27. Stroop SD, Kuestner RE, Serwold TF, Chen L, Moore EE. Chimeric human calcitonin and glucagon receptors reveal two dissociable calcitonin interaction sites. Biochemistry. 1995 Jan 24; 34(3):1050-7. PMID: 7827020.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Serwold's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (185)
Explore
_
Co-Authors (22)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_