Harvard Catalyst Profiles

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Anne Buckingham Young, Ph.D., M.D.


Huntingtin at the post-synaptic density.
Summer, 06/07/04 - 08/20/04

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R25NS065743 (CASH, SYDNEY S) Mar 4, 2009 - Jun 30, 2024
    Neuroscience Resident Research Program
    Role: Co-Principal Investigator
  2. P50NS038372 (YOUNG, ANNE B) Sep 30, 1998 - Sep 14, 2010
    Role: Principal Investigator
  3. R37AG013617 (YOUNG, ANNE B) Aug 15, 1995 - Jul 31, 2011
    Role: Principal Investigator
  4. R01AG013617 (YOUNG, ANNE B) Aug 15, 1995 - Jul 31, 2000
    Role: Principal Investigator
  5. P01AG011337 (YOUNG, ANNE B) May 15, 1994 - Mar 31, 2000
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Aravamuthan BR, Gandham S, Young AB, Rutkove SB. Sex may influence motor phenotype in a novel rodent model of cerebral palsy. Neurobiol Dis. 2020 02; 134:104711. PMID: 31841677; PMCID: PMC9128630.
    Citations: 3     Fields:    Translation:Animals
  2. Chopra V, Quinti L, Khanna P, Paganetti P, Kuhn R, Young AB, Kazantsev AG, Hersch S. LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington's Disease. J Huntingtons Dis. 2016 12 15; 5(4):347-355. PMID: 27983565.
    Citations: 12     Fields:    Translation:AnimalsCells
  3. Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, Selkoe DJ, Sperling RA, St George-Hyslop P, Tanzi RE, Yap L, Young AB, Phelps CH, McCaffrey PG. Massachusetts Alzheimer's Disease Research Center: progress and challenges. Alzheimers Dement. 2015 Oct; 11(10):1241-5. PMID: 26297855; PMCID: PMC4654956.
    Citations: 3     Fields:    Translation:Humans
  4. Moscovitch-Lopatin M, Goodman RE, Eberly S, Ritch JJ, Rosas HD, Matson S, Matson W, Oakes D, Young AB, Shoulson I, Hersch SM. HTRF analysis of soluble huntingtin in PHAROS PBMCs. Neurology. 2013 Sep 24; 81(13):1134-40. PMID: 23966247; PMCID: PMC3795598.
    Citations: 3     Fields:    Translation:HumansCells
  5. Killoran A, Biglan KM, Jankovic J, Eberly S, Kayson E, Oakes D, Young AB, Shoulson I. Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS. Neurology. 2013 May 28; 80(22):2022-7. PMID: 23624566; PMCID: PMC3716408.
    Citations: 25     Fields:    Translation:HumansCells
  6. Sapp E, Valencia A, Li X, Aronin N, Kegel KB, Vonsattel JP, Young AB, Wexler N, DiFiglia M. Native mutant huntingtin in human brain: evidence for prevalence of full-length monomer. J Biol Chem. 2012 Apr 13; 287(16):13487-99. PMID: 22375012.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  7. Ayala R, Kett LR, Leach TL, Young AB, Dunah AW, Orlando LR. Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons. J Neurosci Methods. 2012 Mar 15; 204(2):221-6. PMID: 22155385.
    Citations: 7     Fields:    Translation:AnimalsCells
  8. Cantuti-Castelvetri I, Hernandez LF, Keller-McGandy CE, Kett LR, Landy A, Hollingsworth ZR, Saka E, Crittenden JR, Nillni EA, Young AB, Standaert DG, Graybiel AM. Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats. PLoS One. 2010 Nov 10; 5(11):e13861. PMID: 21085660.
    Citations: 8     Fields:    Translation:Animals
  9. Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wüllner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet JC, Scherzer CR. PGC-1a, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med. 2010 Oct 06; 2(52):52ra73. PMID: 20926834.
    Citations: 373     Fields:    Translation:HumansCells
  10. Young AB. Four decades of neurodegenerative disease research: how far we have come! J Neurosci. 2009 Oct 14; 29(41):12722-8. PMID: 19828782.
    Citations: 22     Fields:    Translation:HumansAnimals
  11. Orlando LR, Ayala R, Kett LR, Curley AA, Duffner J, Bragg DC, Tsai LH, Dunah AW, Young AB. Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5. J Neurochem. 2009 Jul; 110(2):557-69. PMID: 19457112.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  12. Chopra V, Fox JH, Lieberman G, Dorsey K, Matson W, Waldmeier P, Housman DE, Kazantsev A, Young AB, Hersch S. A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse. Proc Natl Acad Sci U S A. 2007 Oct 16; 104(42):16685-9. PMID: 17925440.
    Citations: 52     Fields:    Translation:AnimalsCells
  13. Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27; 317(5837):516-9. PMID: 17588900.
    Citations: 431     Fields:    Translation:HumansAnimalsCells
  14. Coufal M, Maxwell MM, Russel DE, Amore AM, Altmann SM, Hollingsworth ZR, Young AB, Housman DE, Kazantsev AG. Discovery of a novel small-molecule targeting selective clearance of mutant huntingtin fragments. J Biomol Screen. 2007 Apr; 12(3):351-60. PMID: 17379859.
    Citations: 8     Fields:    Translation:AnimalsCells
  15. Altmann SM, Muryshev A, Fossale E, Maxwell MM, Norflus FN, Fox J, Hersch SM, Young AB, MacDonald ME, Abagyan R, Kazantsev AG. Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells. Chem Biol. 2006 Jul; 13(7):765-70. PMID: 16873024.
    Citations: 4     Fields:    Translation:HumansCells
  16. Bodner RA, Outeiro TF, Altmann S, Maxwell MM, Cho SH, Hyman BT, McLean PJ, Young AB, Housman DE, Kazantsev AG. Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. Proc Natl Acad Sci U S A. 2006 Mar 14; 103(11):4246-51. PMID: 16537516; PMCID: PMC1449678.
    Citations: 95     Fields:    Translation:HumansAnimalsCells
  17. Kachroo A, Orlando LR, Grandy DK, Chen JF, Young AB, Schwarzschild MA. Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. J Neurosci. 2005 Nov 09; 25(45):10414-9. PMID: 16280580; PMCID: PMC6725827.
    Citations: 60     Fields:    Translation:Animals
  18. Zhang X, Smith DL, Meriin AB, Engemann S, Russel DE, Roark M, Washington SL, Maxwell MM, Marsh JL, Thompson LM, Wanker EE, Young AB, Housman DE, Bates GP, Sherman MY, Kazantsev AG. A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):892-7. PMID: 15642944; PMCID: PMC545525.
    Citations: 89     Fields:    Translation:AnimalsCells
  19. Zucker B, Luthi-Carter R, Kama JA, Dunah AW, Stern EA, Fox JH, Standaert DG, Young AB, Augood SJ. Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1. Hum Mol Genet. 2005 Jan 15; 14(2):179-89. PMID: 15548548.
    Citations: 42     Fields:    Translation:AnimalsCells
  20. Wexler NS, Lorimer J, Porter J, Gomez F, Moskowitz C, Shackell E, Marder K, Penchaszadeh G, Roberts SA, Gayán J, Brocklebank D, Cherny SS, Cardon LR, Gray J, Dlouhy SR, Wiktorski S, Hodes ME, Conneally PM, Penney JB, Gusella J, Cha JH, Irizarry M, Rosas D, Hersch S, Hollingsworth Z, MacDonald M, Young AB, Andresen JM, Housman DE, De Young MM, Bonilla E, Stillings T, Negrette A, Snodgrass SR, Martinez-Jaurrieta MD, Ramos-Arroyo MA, Bickham J, Ramos JS, Marshall F, Shoulson I, Rey GJ, Feigin A, Arnheim N, Acevedo-Cruz A, Acosta L, Alvir J, Fischbeck K, Thompson LM, Young A, Dure L, O'Brien CJ, Paulsen J, Brickman A, Krch D, Peery S, Hogarth P, Higgins DS, Landwehrmeyer B. Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3498-503. PMID: 14993615; PMCID: PMC373491.
    Citations: 251     Fields:    Translation:HumansCells
  21. Bai L, Hof PR, Standaert DG, Xing Y, Nelson SE, Young AB, Magnusson KR. Changes in the expression of the NR2B subunit during aging in macaque monkeys. Neurobiol Aging. 2004 Feb; 25(2):201-8. PMID: 14749138.
    Citations: 26     Fields:    Translation:Animals
  22. Luthi-Carter R, Apostol BL, Dunah AW, DeJohn MM, Farrell LA, Bates GP, Young AB, Standaert DG, Thompson LM, Cha JH. Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation. Neurobiol Dis. 2003 Dec; 14(3):624-36. PMID: 14678777.
    Citations: 25     Fields:    Translation:AnimalsCells
  23. Yohrling GJ, Jiang GC, DeJohn MM, Miller DW, Young AB, Vrana KE, Cha JH. Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology. Brain Res Mol Brain Res. 2003 Nov 06; 119(1):28-36. PMID: 14597227.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  24. Gomez-Isla T, Irizarry MC, Mariash A, Cheung B, Soto O, Schrump S, Sondel J, Kotilinek L, Day J, Schwarzschild MA, Cha JH, Newell K, Miller DW, Uéda K, Young AB, Hyman BT, Ashe KH. Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice. Neurobiol Aging. 2003 Mar-Apr; 24(2):245-58. PMID: 12498958.
    Citations: 61     Fields:    Translation:HumansAnimals
  25. Young AB. Huntingtin in health and disease. J Clin Invest. 2003 Feb; 111(3):299-302. PMID: 12569151; PMCID: PMC151871.
    Citations: 31     Fields:    Translation:HumansAnimals
  26. Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, Peters NL, Woods AM, Chan EY, Kooperberg C, Krainc D, Young AB, Tapscott SJ, Olson JM. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet. 2002 Aug 15; 11(17):1911-26. PMID: 12165554.
    Citations: 138     Fields:    Translation:HumansAnimalsCells
  27. Luthi-Carter R, Strand AD, Hanson SA, Kooperberg C, Schilling G, La Spada AR, Merry DE, Young AB, Ross CA, Borchelt DR, Olson JM. Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum Mol Genet. 2002 Aug 15; 11(17):1927-37. PMID: 12165555.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  28. Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Hum Mol Genet. 2002 Aug 15; 11(17):1939-51. PMID: 12165556.
    Citations: 40     Fields:    Translation:HumansAnimals
  29. Spektor BS, Miller DW, Hollingsworth ZR, Kaneko YA, Solano SM, Johnson JM, Penney JB, Young AB, Luthi-Carter R. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Res Mol Brain Res. 2002 Jun 15; 102(1-2):118-28. PMID: 12191502.
    Citations: 13     Fields:    Translation:AnimalsCells
  30. Dunah AW, Jeong H, Griffin A, Kim YM, Standaert DG, Hersch SM, Mouradian MM, Young AB, Tanese N, Krainc D. Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science. 2002 Jun 21; 296(5576):2238-43. PMID: 11988536.
    Citations: 238     Fields:    Translation:HumansAnimalsCells
  31. Magnusson KR, Nelson SE, Young AB. Age-related changes in the protein expression of subunits of the NMDA receptor. Brain Res Mol Brain Res. 2002 Feb 28; 99(1):40-5. PMID: 11869807.
    Citations: 53     Fields:    Translation:AnimalsCells
  32. Kosinski CM, Standaert DG, Counihan TJ, Scherzer CR, Kerner JA, Daggett LP, Veliçelebi G, Penney JB, Young AB, Landwehrmeyer GB. Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus. J Comp Neurol. 1998 Jan 05; 390(1):63-74. PMID: 9456176.
    Citations: 15     Fields:    Translation:Humans
  33. Orlando LR, Luthi-Carter R, Standaert DG, Coyle JT, Penney JB, Young AB. N-acetylaspartylglutamate (NAAG) protects against rat striatal quinolinic acid lesions in vivo. Neurosci Lett. 1997 Oct 31; 236(2):91-4. PMID: 9404819.
    Citations: 3     Fields:    Translation:Animals
  34. Testa CM, Hollingsworth ZR, Shinozaki H, Penney JB, Young AB. Selective metabotropic receptor agonists distinguish non-ionotropic glutamate binding sites. Brain Res. 1997 Oct 31; 773(1-2):15-27. PMID: 9409700.
    Citations:    Fields:    Translation:AnimalsCells
  35. Sapp E, Schwarz C, Chase K, Bhide PG, Young AB, Penney J, Vonsattel JP, Aronin N, DiFiglia M. Huntingtin localization in brains of normal and Huntington's disease patients. Ann Neurol. 1997 Oct; 42(4):604-12. PMID: 9382472.
    Citations: 104     Fields:    Translation:HumansCells
  36. Wüllner U, Standaert DG, Testa CM, Penney JB, Young AB. Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain. Brain Res. 1997 Sep 12; 768(1-2):215-23. PMID: 9369318.
    Citations: 8     Fields:    Translation:Animals
  37. Kerner JA, Standaert DG, Penney JB, Young AB, Landwehrmeyer GB. Expression of group one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus. Brain Res Mol Brain Res. 1997 Sep; 48(2):259-69. PMID: 9332723.
    Citations: 42     Fields:    Translation:AnimalsCells
  38. Priller J, Scherzer CR, Faber PW, MacDonald ME, Young AB. Frataxin gene of Friedreich's ataxia is targeted to mitochondria. Ann Neurol. 1997 Aug; 42(2):265-9. PMID: 9266741.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  39. Lin FF, Varney M, Sacaan AI, Jachec C, Daggett LP, Rao S, Flor P, Kuhn R, Kerner JA, Standaert D, Young AB, Veliçelebi G. Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype. Neuropharmacology. 1997 Jul; 36(7):917-31. PMID: 9257936.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  40. Kosinski CM, Cha JH, Young AB, Persichetti F, MacDonald M, Gusella JF, Penney JB, Standaert DG. Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons. Exp Neurol. 1997 Apr; 144(2):239-47. PMID: 9168825.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  41. Scherzer CR, Landwehrmeyer GB, Kerner JA, Standaert DG, Hollingsworth ZR, Daggett LP, Veliçelebi G, Penney JB, Young AB. Cellular distribution of NMDA glutamate receptor subunit mRNAs in the human cerebellum. Neurobiol Dis. 1997; 4(1):35-46. PMID: 9258910.
    Citations: 9     Fields:    Translation:Humans
  42. Standaert DG, Landwehrmeyer GB, Kerner JA, Penney JB, Young AB. Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus. Brain Res Mol Brain Res. 1996 Nov; 42(1):89-102. PMID: 8915584.
    Citations: 52     Fields:    Translation:AnimalsCells
  43. Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M. Expression of normal and mutant huntingtin in the developing brain. J Neurosci. 1996 Sep 01; 16(17):5523-35. PMID: 8757264; PMCID: PMC6578889.
    Citations: 62     Fields:    Translation:HumansAnimals
  44. Rudolf GD, Cronin CA, Landwehrmeyer GB, Standaert DG, Penney JB, Young AB. Expression of N-methyl-D-aspartate glutamate receptor subunits in the prefrontal cortex of the rat. Neuroscience. 1996 Jul; 73(2):417-27. PMID: 8783259.
    Citations: 12     Fields:    Translation:AnimalsCells
  45. Penney JB, Standaert DG, Testa CM, Landwehrmeyer GB, Young AB. Glutamate receptor genes in Parkinson's disease. Adv Neurol. 1996; 69:79-86. PMID: 8615188.
    Citations:    Fields:    Translation:HumansAnimalsCells
  46. Orlando LR, Standaert DG, Penney JB, Young AB. Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neurosci Lett. 1995 Dec 29; 202(1-2):109-12. PMID: 8787843.
    Citations: 6     Fields:    Translation:AnimalsCells
  47. Runge VM, Wells JW, Williams NM, Lee C, Timoney JF, Young AB. Detectability of early brain meningitis with magnetic resonance imaging. Invest Radiol. 1995 Aug; 30(8):484-95. PMID: 8557515.
    Citations: 4     Fields:    Translation:Animals
  48. Landwehrmeyer GB, Standaert DG, Testa CM, Penney JB, Young AB. NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. J Neurosci. 1995 Jul; 15(7 Pt 2):5297-307. PMID: 7623152; PMCID: PMC6577881.
    Citations: 82     Fields:    Translation:AnimalsCells
  49. Dure LS, Wiess S, Standaert DG, Rudolf G, Testa CM, Young AB. DNA fragmentation and immediate early gene expression in rat striatum following quinolinic acid administration. Exp Neurol. 1995 Jun; 133(2):207-14. PMID: 7649226.
    Citations: 1     Fields:    Translation:Animals
  50. Testa CM, Standaert DG, Landwehrmeyer GB, Penney JB, Young AB. Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons. J Comp Neurol. 1995 Apr 03; 354(2):241-52. PMID: 7782501.
    Citations: 44     Fields:    Translation:AnimalsCells
  51. Albin RL, Young AB, Penney JB. The functional anatomy of disorders of the basal ganglia. Trends Neurosci. 1995 Feb; 18(2):63-4. PMID: 7537410.
    Citations: 90     Fields:    Translation:HumansAnimals
  52. Sapp E, Ge P, Aizawa H, Bird E, Penney J, Young AB, Vonsattel JP, DiFiglia M. Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis. Neuroscience. 1995 Jan; 64(2):397-404. PMID: 7535402.
    Citations: 42     Fields:    Translation:Humans
  53. Wüllner U, Young AB, Penney JB, Beal MF. 3-Nitropropionic acid toxicity in the striatum. J Neurochem. 1994 Nov; 63(5):1772-81. PMID: 7523600.
    Citations: 18     Fields:    Translation:AnimalsCells
  54. Catania MV, Landwehrmeyer GB, Testa CM, Standaert DG, Penney JB, Young AB. Metabotropic glutamate receptors are differentially regulated during development. Neuroscience. 1994 Aug; 61(3):481-95. PMID: 7969925.
    Citations: 45     Fields:    Translation:AnimalsCells
  55. Wüllner U, Standaert DG, Testa CM, Landwehrmeyer GB, Catania MV, Penney JB, Young AB. Glutamate receptor expression in rat striatum: effect of deafferentation. Brain Res. 1994 Jun 06; 647(2):209-19. PMID: 7922497.
    Citations: 8     Fields:    Translation:AnimalsCells
  56. Wüllner U, Testa CM, Catania MV, Young AB, Penney JB. Glutamate receptors in striatum and substantia nigra: effects of medial forebrain bundle lesions. Brain Res. 1994 May 09; 645(1-2):98-102. PMID: 8062103.
    Citations: 8     Fields:    Translation:AnimalsCells
  57. Standaert DG, Testa CM, Young AB, Penney JB. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. J Comp Neurol. 1994 May 01; 343(1):1-16. PMID: 8027428.
    Citations: 73     Fields:    Translation:AnimalsCells
  58. Testa CM, Standaert DG, Young AB, Penney JB. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J Neurosci. 1994 May; 14(5 Pt 2):3005-18. PMID: 8182455; PMCID: PMC6577508.
    Citations: 131     Fields:    Translation:AnimalsCells
  59. Catania MV, De Socarraz H, Penney JB, Young AB. Metabotropic glutamate receptor heterogeneity in rat brain. Mol Pharmacol. 1994 Apr; 45(4):626-36. PMID: 8183241.
    Citations: 8     Fields:    Translation:Animals
  60. Arregui A, Hollingsworth Z, Penney JB, Young AB. Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice. Neurosci Lett. 1994 Feb 14; 167(1-2):195-7. PMID: 8177524.
    Citations: 5     Fields:    Translation:AnimalsCells
  61. Fotuhi M, Standaert DG, Testa CM, Penney JB, Young AB. Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat. Brain Res Mol Brain Res. 1994 Feb; 21(3-4):283-92. PMID: 8170352.
    Citations: 26     Fields:    Translation:Animals
  62. Hyman BT, Penney JB, Blackstone CD, Young AB. Localization of non-N-methyl-D-aspartate glutamate receptors in normal and Alzheimer hippocampal formation. Ann Neurol. 1994 Jan; 35(1):31-7. PMID: 8285589.
    Citations: 4     Fields:    Translation:Humans
  63. Young AB. Future directions for research on Alzheimer's disease. Neurobiol Aging. 1994; 15 Suppl 2:S73. PMID: 7700467.
    Citations:    Fields:    Translation:Humans
  64. Toler SM, Young AB, McClain CJ, Shedlofsky SI, Bandyopadhyay AM, Blouin RA. Head injury and cytochrome P-450 enzymes. Differential effect on mRNA and protein expression in the Fischer-344 rat. Drug Metab Dispos. 1993 Nov-Dec; 21(6):1064-9. PMID: 7905385.
    Citations: 8     Fields:    Translation:AnimalsCells
  65. Henry TR, Frey KA, Sackellares JC, Gilman S, Koeppe RA, Brunberg JA, Ross DA, Berent S, Young AB, Kuhl DE. In vivo cerebral metabolism and central benzodiazepine-receptor binding in temporal lobe epilepsy. Neurology. 1993 Oct; 43(10):1998-2006. PMID: 8413957.
    Citations: 16     Fields:    Translation:Humans
  66. Holthoff VA, Koeppe RA, Frey KA, Penney JB, Markel DS, Kuhl DE, Young AB. Positron emission tomography measures of benzodiazepine receptors in Huntington's disease. Ann Neurol. 1993 Jul; 34(1):76-81. PMID: 8390806.
    Citations: 16     Fields:    Translation:Humans
  67. Price RH, Albin RL, Sakurai SY, Polinsky RJ, Penney JB, Young AB. Cerebellar excitatory and inhibitory amino acid receptors in multiple system atrophy. Neurology. 1993 Jul; 43(7):1323-8. PMID: 8392149.
    Citations: 1     Fields:    Translation:Humans
  68. Carlson MD, Penney JB, Young AB. NMDA, AMPA, and benzodiazepine binding site changes in Alzheimer's disease visual cortex. Neurobiol Aging. 1993 Jul-Aug; 14(4):343-52. PMID: 7690114.
    Citations: 6     Fields:    Translation:HumansCells
  69. Wüllner U, Brouillet E, Isacson O, Young AB, Penney JB. Glutamate receptor binding sites in MPTP-treated mice. Exp Neurol. 1993 Jun; 121(2):284-7. PMID: 8393409.
    Citations: 2     Fields:    Translation:AnimalsCells
  70. Beach L, Young AB, Patchell RA. A template for rigid stereotaxic afterloading brachytherapy of the brain. Int J Radiat Oncol Biol Phys. 1993 May 20; 26(2):347-51. PMID: 8491692.
    Citations: 1     Fields:    Translation:Humans
  71. Standaert DG, Testa CM, Penney JB, Young AB. Alternatively spliced isoforms of the NMDAR1 glutamate receptor subunit: differential expression in the basal ganglia of the rat. Neurosci Lett. 1993 Apr 02; 152(1-2):161-4. PMID: 8515871.
    Citations: 8     Fields:    Translation:AnimalsCells
  72. Sakurai SY, Penney JB, Young AB. Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain. J Neurochem. 1993 Apr; 60(4):1344-53. PMID: 8095974.
    Citations: 17     Fields:    Translation:Animals
  73. Catania MV, Hollingsworth Z, Penney JB, Young AB. Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites. Neuroreport. 1993 Mar; 4(3):311-3. PMID: 7682857.
    Citations: 3     Fields:    Translation:AnimalsCells
  74. Price RH, Hollingsworth Z, Young AB, Penney JB. Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat. Brain Res. 1993 Jan 29; 602(1):157-60. PMID: 8383570.
    Citations: 3     Fields:    Translation:Animals
  75. Young AB. Role of excitotoxins in heredito-degenerative neurologic diseases. Res Publ Assoc Res Nerv Ment Dis. 1993; 71:175-89. PMID: 8093331.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  76. Catania MV, Hollingsworth Z, Penney JB, Young AB. Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence. J Neurochem. 1993 Jan; 60(1):236-45. PMID: 7678040.
    Citations: 9     Fields:    Translation:Animals
  77. Kincaid AE, Albin RL, Newman SW, Penney JB, Young AB. 6-Hydroxydopamine lesions of the nigrostriatal pathway alter the expression of glutamate decarboxylase messenger RNA in rat globus pallidus projection neurons. Neuroscience. 1992 Dec; 51(3):705-18. PMID: 1488118.
    Citations: 12     Fields:    Translation:AnimalsCells
  78. Dure LS, Young AB, Penney JB. Compartmentalization of excitatory amino acid receptors in human striatum. Proc Natl Acad Sci U S A. 1992 Aug 15; 89(16):7688-92. PMID: 1380163; PMCID: PMC49776.
    Citations: 3     Fields:    Translation:Humans
  79. Kimbrough BO, Young AB, Modica LA. Orbital cellulitis and cavernous sinus thrombosis after cataract extraction and lens implantation. Ann Ophthalmol. 1992 Aug; 24(8):313-7. PMID: 1416632.
    Citations: 2     Fields:    Translation:Humans
  80. Tallaksen-Greene SJ, Young AB, Penney JB, Beitz AJ. Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat. Neurosci Lett. 1992 Jul 06; 141(1):79-83. PMID: 1324445.
    Citations: 24     Fields:    Translation:AnimalsCells
  81. Cha JH, Makowiec RL, Penney JB, Young AB. Multiple states of rat brain (RS)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors as revealed by quantitative autoradiography. Mol Pharmacol. 1992 May; 41(5):832-8. PMID: 1375315.
    Citations: 5     Fields:    Translation:AnimalsCells
  82. Olson JM, McNeel W, Young AB, Mancini WR. Localization of the peripheral-type benzodiazepine binding site to mitochondria of human glioma cells. J Neurooncol. 1992 May; 13(1):35-42. PMID: 1319474.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  83. Bowen DM, Francis PT, Procter AW, Young AB. Treatment of Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1992 Apr; 55(4):328. PMID: 1316431; PMCID: PMC489052.
    Citations: 1     Fields:    Translation:HumansCells
  84. Albin RL, Reiner A, Anderson KD, Dure LS, Handelin B, Balfour R, Whetsell WO, Penney JB, Young AB. Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Ann Neurol. 1992 Apr; 31(4):425-30. PMID: 1375014.
    Citations: 97     Fields:    Translation:HumansCells
  85. Difazio MC, Hollingsworth Z, Young AB, Penney JB. Glutamate receptors in the substantia nigra of Parkinson's disease brains. Neurology. 1992 Feb; 42(2):402-6. PMID: 1346548.
    Citations: 9     Fields:    Translation:Humans
  86. Albin RL, Makowiec RL, Hollingsworth ZR, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study. Neuroscience. 1992; 46(1):35-48. PMID: 1317515.
    Citations: 52     Fields:    Translation:Animals
  87. Dure LS, Young AB, Penney JB. Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease. Ann Neurol. 1991 Dec; 30(6):785-93. PMID: 1665055.
    Citations: 18     Fields:    Translation:HumansCells
  88. Albin RL, Sakurai SY, Makowiec RL, Higgins DS, Young AB, Penney JB. Excitatory amino acid, GABA(A), and GABA(B) binding sites in human striate cortex. Cereb Cortex. 1991 Nov-Dec; 1(6):499-509. PMID: 1668367.
    Citations: 1     Fields:    Translation:Humans
  89. Cha JH, Dure LS IV, Sakurai SY, Penney JB, Young AB. 2,4,5-Trihydroxyphenylalanine (6-hydroxy-dopa) displaces [3H]AMPA binding in rat striatum. Neurosci Lett. 1991 Oct 28; 132(1):55-8. PMID: 1664920.
    Citations: 3     Fields:    Translation:AnimalsCells
  90. Albin RL, Qin Y, Young AB, Penney JB, Chesselet MF. Preproenkephalin messenger RNA-containing neurons in striatum of patients with symptomatic and presymptomatic Huntington's disease: an in situ hybridization study. Ann Neurol. 1991 Oct; 30(4):542-9. PMID: 1838677.
    Citations: 18     Fields:    Translation:HumansCells
  91. Albin RL, Price RH, Sakurai SY, Penney JB, Young AB. Excitatory and inhibitory amino acid binding sites in human dentate nucleus. Brain Res. 1991 Sep 27; 560(1-2):350-3. PMID: 1760743.
    Citations:    Fields:    Translation:HumansCells
  92. Kincaid AE, Penney JB, Young AB, Newman SW. Evidence for a projection from the globus pallidus to the entopeduncular nucleus in the rat. Neurosci Lett. 1991 Jul 08; 128(1):121-5. PMID: 1656332.
    Citations: 16     Fields:    Translation:AnimalsCells
  93. Kincaid AE, Penney JB, Young AB, Newman SW. The globus pallidus receives a projection from the parafascicular nucleus in the rat. Brain Res. 1991 Jul 05; 553(1):18-26. PMID: 1933274.
    Citations: 16     Fields:    Translation:AnimalsCells
  94. Vogel CM, Drury I, Terry LC, Young AB. Myoclonus in adult Huntington's disease. Ann Neurol. 1991 Feb; 29(2):213-5. PMID: 1826419.
    Citations: 6     Fields:    Translation:Humans
  95. Maragos WF, Greenamyre JT, Chu DC, Penney JB, Young AB. A study of cortical and hippocampal NMDA and PCP receptors following selective cortical and subcortical lesions. Brain Res. 1991 Jan 04; 538(1):36-45. PMID: 1850317.
    Citations: 3     Fields:    Translation:AnimalsCells
  96. Sakurai SY, Cha JH, Penney JB, Young AB. Regional distribution and properties of [3H]MK-801 binding sites determined by quantitative autoradiography in rat brain. Neuroscience. 1991; 40(2):533-43. PMID: 2027471.
    Citations: 12     Fields:    Translation:AnimalsCells
  97. Brewer GJ, Dick RD, Yuzbasiyan-Gurkin V, Tankanow R, Young AB, Kluin KJ. Initial therapy of patients with Wilson's disease with tetrathiomolybdate. Arch Neurol. 1991 Jan; 48(1):42-7. PMID: 1986725.
    Citations: 32     Fields:    Translation:Humans
  98. Makowiec RL, Cha JJ, Penney JB, Young AB. Cerebellar excitatory amino acid binding sites in normal, granuloprival, and Purkinje cell-deficient mice. Neuroscience. 1991; 42(3):671-81. PMID: 1683473.
    Citations: 3     Fields:    Translation:AnimalsCells
  99. Rapp RP, Billeter M, Hatton J, Young AB, Tibbs PA, Dempsey RJ. Intravenous ciprofloxacin versus ceftazidime for treatment of nosocomial pneumonia and urinary tract infection. Clin Pharm. 1991 Jan; 10(1):49-55. PMID: 1999086.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  100. Young AB, Dauth GW, Hollingsworth Z, Penney JB, Kaatz K, Gilman S. Quisqualate- and NMDA-sensitive [3H]glutamate binding in primate brain. J Neurosci Res. 1990 Dec; 27(4):512-21. PMID: 1981916.
    Citations: 7     Fields:    Translation:Animals
  101. McDonald JW, Johnston MV, Young AB. Differential ontogenic development of three receptors comprising the NMDA receptor/channel complex in the rat hippocampus. Exp Neurol. 1990 Dec; 110(3):237-47. PMID: 2174375.
    Citations: 20     Fields:    Translation:AnimalsCells
  102. Albin RL, Makowiec RL, Hollingsworth Z, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the periaqueductal gray of the rat. Neurosci Lett. 1990 Oct 02; 118(1):112-5. PMID: 2175406.
    Citations: 13     Fields:    Translation:Animals
  103. Makowiec RL, Albin RL, Cha JH, Young AB, Gilman S. Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex. Brain Res. 1990 Jul 23; 523(2):309-12. PMID: 1976026.
    Citations: 1     Fields:    Translation:Humans
  104. Young AB. What's the excitement about excitatory amino acids in amyotrophic lateral sclerosis? Ann Neurol. 1990 Jul; 28(1):9-11. PMID: 2375640.
    Citations: 1     Fields:    Translation:Humans
  105. Cha JH, Makowiec RL, Penney JB, Young AB. L-[3H]glutamate labels the metabotropic excitatory amino acid receptor in rodent brain. Neurosci Lett. 1990 May 18; 113(1):78-83. PMID: 1973276.
    Citations: 8     Fields:    Translation:Animals
  106. Albin RL, Young AB, Penney JB, Handelin B, Balfour R, Anderson KD, Markel DS, Tourtellotte WW, Reiner A. Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease. N Engl J Med. 1990 May 03; 322(18):1293-8. PMID: 1691447.
    Citations: 60     Fields:    Translation:HumansCells
  107. Penney JB, Maragos WF, Greenamyre JT, Debowey DL, Hollingsworth Z, Young AB. Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias. J Neurol Neurosurg Psychiatry. 1990 Apr; 53(4):314-20. PMID: 2160518; PMCID: PMC1014169.
    Citations: 11     Fields:    Translation:Humans
  108. Albin RL, Reiner A, Anderson KD, Penney JB, Young AB. Striatal and nigral neuron subpopulations in rigid Huntington's disease: implications for the functional anatomy of chorea and rigidity-akinesia. Ann Neurol. 1990 Apr; 27(4):357-65. PMID: 1972318.
    Citations: 55     Fields:    Translation:Humans
  109. Greenamyre JT, Higgins DS, Young AB. Sodium-dependent D-aspartate 'binding' is not a measure of presynaptic neuronal uptake sites in an autoradiographic assay. Brain Res. 1990 Mar 19; 511(2):310-8. PMID: 2159361.
    Citations: 1     Fields:    Translation:Animals
  110. Young AB, Fagg GE. Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches. Trends Pharmacol Sci. 1990 Mar; 11(3):126-33. PMID: 1966569.
    Citations: 38     Fields:    Translation:AnimalsCells
  111. Nielsen EO, Drejer J, Cha JH, Young AB, Honoré T. Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites. J Neurochem. 1990 Feb; 54(2):686-95. PMID: 1967632.
    Citations: 13     Fields:    Translation:AnimalsCells
  112. Mulcahy JJ, Young AB. Long-term follow-up of percutaneous radiofrequency sacral rhizotomy. Urology. 1990 Jan; 35(1):76-7. PMID: 2296824.
    Citations: 2     Fields:    Translation:Humans
  113. Greenamyre JT, Higgins DS, Young AB, Penney JB. Regional ontogeny of a unique glutamate recognition site in rat brain: an autoradiographic study. Int J Dev Neurosci. 1990; 8(4):437-45. PMID: 2174635.
    Citations: 2     Fields:    Translation:Animals
  114. McDonald JW, Penney JB, Johnston MV, Young AB. Characterization and regional distribution of strychnine-insensitive [3H]glycine binding sites in rat brain by quantitative receptor autoradiography. Neuroscience. 1990; 35(3):653-68. PMID: 2166246.
    Citations: 9     Fields:    Translation:AnimalsCells
  115. Chu DC, Albin RL, Young AB, Penney JB. Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study. Neuroscience. 1990; 34(2):341-57. PMID: 2159128.
    Citations: 59     Fields:    Translation:AnimalsCells
  116. Luce EA, Vasconez HC, Young AB. Maxillofacial trauma. J Ky Med Assoc. 1990 Jan; 88(1):21-8. PMID: 2295865.
    Citations:    Fields:    Translation:Humans
  117. Penney JB, Young AB, Shoulson I, Starosta-Rubenstein S, Snodgrass SR, Sanchez-Ramos J, Ramos-Arroyo M, Gomez F, Penchaszadeh G, Alvir J, et al. Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals. Mov Disord. 1990; 5(2):93-9. PMID: 2139171.
    Citations: 44     Fields:    Translation:Humans
  118. Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends Neurosci. 1989 Oct; 12(10):366-75. PMID: 2479133.
    Citations: 1372     Fields:    Translation:Humans
  119. Schwartz RW, Simpson WG, Strodel WE, Jarecky RK, Griffen WO, Young AB. Career change: in quest of a controllable lifestyle. J Surg Res. 1989 Sep; 47(3):189-92. PMID: 2770274.
    Citations: 13     Fields:    Translation:Humans
  120. Greenamyre JT, Young AB. Excitatory amino acids and Alzheimer's disease. Neurobiol Aging. 1989 Sep-Oct; 10(5):593-602. PMID: 2554168.
    Citations: 73     Fields:    Translation:HumansAnimals
  121. Richfield EK, Young AB, Penney JB. Comparative distributions of dopamine D-1 and D-2 receptors in the cerebral cortex of rats, cats, and monkeys. J Comp Neurol. 1989 Aug 22; 286(4):409-26. PMID: 2506254.
    Citations: 25     Fields:    Translation:Animals
  122. Conneally PM, Haines JL, Tanzi RE, Wexler NS, Penchaszadeh GK, Harper PS, Folstein SE, Cassiman JJ, Myers RH, Young AB, et al. Huntington disease: no evidence for locus heterogeneity. Genomics. 1989 Aug; 5(2):304-8. PMID: 2571579.
    Citations: 17     Fields:    Translation:Humans
  123. Albin RL, Aldridge JW, Young AB, Gilman S. Feline subthalamic nucleus neurons contain glutamate-like but not GABA-like or glycine-like immunoreactivity. Brain Res. 1989 Jul 03; 491(1):185-8. PMID: 2569908.
    Citations: 13     Fields:    Translation:Animals
  124. Greenamyre JT, Young AB. Synaptic localization of striatal NMDA, quisqualate and kainate receptors. Neurosci Lett. 1989 Jun 19; 101(2):133-7. PMID: 2549458.
    Citations: 10     Fields:    Translation:Animals
  125. Yang DJ, Ciliax BJ, Van Dort ME, Gildersleeve D, Pirat JL, Young AB, Wieland DM. Synthesis and receptor binding studies of (+/-)1-iodo-MK-801. Pharm Res. 1989 Jun; 6(6):474-6. PMID: 2548173.
    Citations:    Fields:    Translation:Animals
  126. McDonald JW, Cline HT, Constantine-Paton M, Maragos WF, Johnston MV, Young AB. Quantitative autoradiographic localization of NMDA, quisqualate and PCP receptors in the frog tectum. Brain Res. 1989 Mar 13; 482(1):155-8. PMID: 2539881.
    Citations: 3     Fields:    Translation:Animals
  127. Cha JH, Hollingsworth ZR, Greenamyre JT, Young AB. Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances. J Neurosci Methods. 1989 Mar; 27(2):143-8. PMID: 2565415.
    Citations: 1     Fields:    Translation:PHPublic Health
  128. Gildersleeve DL, Lin TY, Wieland DM, Ciliax BJ, Olson JM, Young AB. Synthesis of a high specific activity 125I-labeled analog of PK 11195, potential agent for SPECT imaging of the peripheral benzodiazepine binding site. Int J Rad Appl Instrum B. 1989; 16(4):423-9. PMID: 2550392.
    Citations: 7     Fields:    Translation:HumansAnimals
  129. Richfield EK, Penney JB, Young AB. Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system. Neuroscience. 1989; 30(3):767-77. PMID: 2528080.
    Citations: 146     Fields:    Translation:AnimalsCells
  130. Irwin CC, Wexler NS, Young AB, Ozelius LJ, Penney JB, Shoulson I, Snodgrass SR, Ramos-Arroyo MA, Sanchez-Ramos J, Penchaszadeh GK, et al. The role of mitochondrial DNA in Huntington's disease. J Mol Neurosci. 1989; 1(2):129-36. PMID: 2534902.
    Citations: 3     Fields:    Translation:HumansCells
  131. Nielsen EO, Cha JH, Honoré T, Penney JB, Young AB. Thiocyanate stabilizes AMPA binding to the quisqualate receptor. Eur J Pharmacol. 1988 Nov 22; 157(2-3):197-203. PMID: 2906292.
    Citations: 3     Fields:    Translation:Animals
  132. Van Dort ME, Ciliax BJ, Gildersleeve DL, Sherman PS, Rosenspire KC, Young AB, Junck L, Wieland DM. Radioiodinated benzodiazepines: agents for mapping glial tumors. J Med Chem. 1988 Nov; 31(11):2081-6. PMID: 2846836.
    Citations: 5     Fields:    Translation:AnimalsCells
  133. Roy MW, Dempsey RJ, Meyer KL, Donaldson DL, Tibbs PA, Young AB. Effects of verapamil and diltiazem on acute stroke in cats. J Neurosurg. 1985 Dec; 63(6):929-36. PMID: 4056906.
    Citations: 4     Fields:    Translation:Animals
  134. Twyman D, Young AB, Ott L, Norton JA, Bivins BA. High protein enteral feedings: a means of achieving positive nitrogen balance in head injured patients. JPEN J Parenter Enteral Nutr. 1985 Nov-Dec; 9(6):679-84. PMID: 3934402.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  135. Pan HS, Penney JB, Young AB. Gamma-aminobutyric acid and benzodiazepine receptor changes induced by unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. J Neurochem. 1985 Nov; 45(5):1396-404. PMID: 2995585.
    Citations: 22     Fields:    Translation:Animals
  136. Young AB. Progressive supranuclear palsy: postmortem chemical analysis. Ann Neurol. 1985 Nov; 18(5):521-2. PMID: 2866753.
    Citations: 2     Fields:    Translation:Humans
  137. Aisen AM, Martel W, Gabrielsen TO, Glazer GM, Brewer G, Young AB, Hill G. Wilson disease of the brain: MR imaging. Radiology. 1985 Oct; 157(1):137-41. PMID: 4034959.
    Citations: 25     Fields:    Translation:Humans
  138. Bertch KE, Norton JA, Young AB, Rapp RP, Tibbs PA. A comparative study of laboratory parameters in head-injured patients receiving either phenytoin or placebo for 24 months. Drug Intell Clin Pharm. 1985 Jul-Aug; 19(7-8):561-6. PMID: 3896716.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  139. Greenamyre JT, Olson JM, Penney JB, Young AB. Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites. J Pharmacol Exp Ther. 1985 Apr; 233(1):254-63. PMID: 2984415.
    Citations: 39     Fields:    Translation:Animals
  140. Johnston MV, Silverstein FS, Reindel FO, Penney JB, Young AB. Muscarinic cholinergic receptors in human infant forebrain: [3H]quinuclidinyl benzilate binding in homogenates and quantitative autoradiography in sections. Brain Res. 1985 Apr; 351(2):195-203. PMID: 3995346.
    Citations: 1     Fields:    Translation:HumansCells
  141. Greenamyre JT, Penney JB, Young AB, D'Amato CJ, Hicks SP, Shoulson I. Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases. Science. 1985 Mar 22; 227(4693):1496-9. PMID: 2858129.
    Citations: 32     Fields:    Translation:HumansCells
  142. Abou-Khalil B, Young AB, Penney JB. Evidence for the presynaptic localization of opiate binding sites on striatal efferent fibers. Brain Res. 1984 Dec 03; 323(1):21-9. PMID: 6098334.
    Citations: 6     Fields:    Translation:AnimalsCells
  143. Goldstein SJ, Lee C, Young AB, Guidry GJ. Aplasia of the cervical internal carotid artery and malformation of the circle of Willis associated with Klippel-Trenaunay syndrome. Case report. J Neurosurg. 1984 Oct; 61(4):786-9. PMID: 6088733.
    Citations: 3     Fields:    Translation:Humans
  144. Walker FO, Young AB, Penney JB, Dovorini-Zis K, Shoulson I. Benzodiazepine and GABA receptors in early Huntington's disease. Neurology. 1984 Sep; 34(9):1237-40. PMID: 6087209.
    Citations: 10     Fields:    Translation:Humans
  145. Pan HS, Penney JB, Young AB. Characterization of benzodiazepine receptor changes in substantia nigra, globus pallidus and entopeduncular nucleus after striatal lesions. J Pharmacol Exp Ther. 1984 Sep; 230(3):768-75. PMID: 6147405.
    Citations: 1     Fields:    Translation:AnimalsCells
  146. Young AB, Penney JB. Neurochemical anatomy of movement disorders. Neurol Clin. 1984 Aug; 2(3):417-33. PMID: 6152481.
    Citations: 9     Fields:    Translation:Humans
  147. Greenamyre JT, Young AB, Penney JB. Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system. J Neurosci. 1984 Aug; 4(8):2133-44. PMID: 6088729; PMCID: PMC6564945.
    Citations: 32     Fields:    Translation:Animals
  148. Maruyama Y, Chin HW, Young AB, Wang PC, Tibbs P, Beach JL, Goldstein S. Implantation of brain tumors with Cf-252. Use of computed tomography and magnetic resonance imaging to guide insertion and evaluate response. Radiology. 1984 Jul; 152(1):177-81. PMID: 6729108.
    Citations:    Fields:    Translation:Humans
  149. Young AB, Pan HS, Ciliax BJ, Penney JB. GABA and benzodiazepine receptors in basal ganglia function. Neurosci Lett. 1984 Jun 29; 47(3):361-7. PMID: 6089057.
    Citations: 1     Fields:    Translation:AnimalsCells
  150. Chin HW, Maruyama Y, Young AB. Medulloblastoma: recent advances and directions in diagnosis and management. Part II. Curr Probl Cancer. 1984 Jun; 8(12):1-51. PMID: 6478850.
    Citations:    Fields:    Translation:Humans
  151. Chin HW, Maruyama Y, Young AB. Medulloblastoma: recent advances and directions in diagnosis and management--Part I. Curr Probl Cancer. 1984 May; 8(11):4-54. PMID: 6383718.
    Citations:    Fields:    Translation:Humans
  152. Pan HS, Dauth GW, Young AB, Penney JB. Computer-assisted estimates of lesion sizes and shrinkage in denervated areas from receptor autoradiograms using a digitizing tablet. Neurosci Lett. 1984 Feb 24; 44(3):277-80. PMID: 6728297.
    Citations:    Fields:    Translation:Animals
  153. Maruyama Y, Chin HW, Young AB, Beach J, Tibbs P, Goldstein S, Markesbery W. CT and MR for brain tumor implant therapy using CF-252 neutrons. J Neurooncol. 1984; 2(4):349-60. PMID: 6099406.
    Citations:    Fields:    Translation:Humans
  154. Garden OJ, Morris EW, Young AB. A penetrating wound of bone resulting from a firework. Injury. 1983 Nov; 15(3):167-9. PMID: 6642625.
    Citations: 2     Fields:    Translation:Humans
  155. Young AB, Penney JB, Dauth GW, Bromberg MB, Gilman S. Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey. Neurology. 1983 Nov; 33(11):1513-6. PMID: 6138734.
    Citations: 9     Fields:    Translation:Animals
  156. Mata M, Dorovini-Zis K, Wilson M, Young AB. New form of familial Parkinson-dementia syndrome: clinical and pathologic findings. Neurology. 1983 Nov; 33(11):1439-43. PMID: 6685236.
    Citations: 10     Fields:    Translation:Humans
  157. Wilson JM, Young AB, Kelley WN. Hypoxanthine-guanine phosphoribosyltransferase deficiency. The molecular basis of the clinical syndromes. N Engl J Med. 1983 Oct 13; 309(15):900-10. PMID: 6136913.
    Citations: 28     Fields:    Translation:HumansCells
  158. Goldstein SJ, Wilson DD, Young AB, Guidry GJ. Craniopharyngioma intrinsic to the third ventricle. Surg Neurol. 1983 Sep; 20(3):249-53. PMID: 6879427.
    Citations: 3     Fields:    Translation:Humans
  159. Greenamyre JT, Young AB, Penney JB. Quantitative autoradiography of L-[3H]glutamate binding to rat brain. Neurosci Lett. 1983 Jun 16; 37(2):155-60. PMID: 6136011.
    Citations: 6     Fields:    Translation:Animals
  160. Pan HS, Frey KA, Young AB, Penney JB. Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography. J Neurosci. 1983 Jun; 3(6):1189-98. PMID: 6304260; PMCID: PMC6564610.
    Citations: 14     Fields:    Translation:Animals
  161. Young AB, Reid D, Grist NR. Is cytomegalovirus a serious hazard to female hospital staff? Lancet. 1983 Apr 30; 1(8331):975-6. PMID: 6132279.
    Citations: 1     Fields:    Translation:Humans
  162. Walsh JW, Stevens DB, Young AB. Traumatic paraplegia in children without contiguous spinal fracture or dislocation. Neurosurgery. 1983 Apr; 12(4):439-45. PMID: 6856070.
    Citations: 10     Fields:    Translation:Humans
  163. Penney JB, Young AB. Speculations on the functional anatomy of basal ganglia disorders. Annu Rev Neurosci. 1983; 6:73-94. PMID: 6838141.
    Citations: 46     Fields:    Translation:Humans
  164. Penney JB, Young AB. Quantitative autoradiography of neurotransmitter receptors in Huntington disease. Neurology. 1982 Dec; 32(12):1391-5. PMID: 6292789.
    Citations: 13     Fields:    Translation:Humans
  165. Maruyama Y, Chin HW, Young AB, Bean J, Tibbs P, Beach JL. Interstitial 252Cf neutron therapy for glioblastoma multiforme. Am J Clin Oncol. 1982 Dec; 5(6):589-91. PMID: 6299091.
    Citations: 2     Fields:    Translation:Humans
  166. Maruyama Y, Chin HW, Young AB, Beach JL, Bean J, Tibbs P. Work in progress: 252Cf neutron brachytherapy for hemispheric malignant glioma. Radiology. 1982 Oct; 145(1):171-4. PMID: 6289375.
    Citations: 4     Fields:    Translation:Humans
  167. Frere RC, Macdonald RL, Young AB. GABA binding and bicuculline in spinal cord and cortical membranes from adult rat and from mouse neurons in cell culture. Brain Res. 1982 Jul 22; 244(1):145-53. PMID: 6288176.
    Citations: 3     Fields:    Translation:AnimalsCells
  168. Nowak LM, Young AB, Macdonald RL. GABA and bicuculline actions on mouse spinal cord and cortical neurons in cell culture. Brain Res. 1982 Jul 22; 244(1):155-64. PMID: 6288177.
    Citations: 15     Fields:    Translation:AnimalsCells
  169. Baker RS, Millett AJ, Young AB, Markesbery WR. Effects of chronic denervation on the histology of canine extraocular muscle. Invest Ophthalmol Vis Sci. 1982 Jun; 22(6):701-5. PMID: 7076415.
    Citations: 6     Fields:    Translation:Animals
  170. Chin HW, Maruyama Y, Markesbery W, Young AB. Intracranial ependymoma: results of radiotherapy at the University of Kentucky. Cancer. 1982 Jun 01; 49(11):2276-80. PMID: 7074543.
    Citations: 13     Fields:    Translation:Humans
  171. Goldstein SJ, Woodring JH, Young AB. Occipital condyle fracture associated with cervical spine injury. Surg Neurol. 1982 May; 17(5):350-2. PMID: 7089849.
    Citations: 4     Fields:    Translation:Humans
  172. Hunter JA, Zoma AA, Scullion JE, Protheroe K, Young AB, Sturrock RD, Capell HA. The geometric knee replacement in polyarthritis. J Bone Joint Surg Br. 1982; 64(1):95-8. PMID: 7068729.
    Citations:    Fields:    Translation:Humans
  173. Muir W, Chin HW, Young AB, Maruyama Y. Proper analysis of clinical trials for malignant glioma. Cancer Treat Rep. 1982 Jan; 66(1):211-3. PMID: 7053262.
    Citations: 1     Fields:    Translation:Humans
  174. Belch JJ, Meek DR, Lowe GD, Campbell AF, Young AB, Forbes CD, Prentice CR. Subcutaneous ancrod in prevention of deep vein thrombosis after hip replacement surgery. Thromb Res. 1982 Jan 1-15; 25(1-2):23-31. PMID: 7038977.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  175. Penney JB, Pan HS, Young AB, Frey KA, Dauth GW. Quantitative autoradiography of [3H]muscimol binding in rat brain. Science. 1981 Nov 27; 214(4524):1036-8. PMID: 6272394.
    Citations: 10     Fields:    Translation:Animals
  176. Macdonald RL, Young AB. Pharmacology of GABA-mediated inhibition of spinal cord neurons in vivo and in primary dissociated cell culture. Mol Cell Biochem. 1981 Aug 11; 38 Spec No(Pt 1):147-62. PMID: 6270545.
    Citations: 3     Fields:    Translation:AnimalsCells
  177. Penney JB, Frey K, Young AB. Quantitative autoradiography of neurotransmitter receptors using tritium-sensitive film. Eur J Pharmacol. 1981 Jul 10; 72(4):421-2. PMID: 6268430.
    Citations: 3     Fields:    Translation:Animals
  178. Lawson LA, Blouin RA, Smith RB, Rapp RP, Young AB. Phenytoin-dexamethasone interaction: a previously unreported observation. Surg Neurol. 1981 Jul; 16(1):23-4. PMID: 7280966.
    Citations: 10     Fields:    Translation:Humans
  179. Grist NR, Reid D, Young AB. Herd immunity to infections. Health Bull (Edinb). 1981 Jul; 39(4):211-7. PMID: 7287424.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  180. Bromberg MB, Penney JB, Stephenson BS, Young AB. Evidence for glutamate as the neurotransmitter of corticothalamic and corticorubral pathways. Brain Res. 1981 Jun 29; 215(1-2):369-74. PMID: 6167322.
    Citations: 11     Fields:    Translation:Animals
  181. Tibbs PA, Young AB, Walsh JW, Bean JR. Pharmacologic and surgical therapy for spasticity. J Ky Med Assoc. 1981 Jun; 79(6):359-62. PMID: 7264443.
    Citations:    Fields:    Translation:Humans
  182. Young AB, Bromberg MB, Penney JB. Decreased glutamate uptake in subcortical areas deafferented by sensorimotor cortical ablation in the cat. J Neurosci. 1981 Mar; 1(3):241-9. PMID: 6114994; PMCID: PMC6564118.
    Citations: 14     Fields:    Translation:Animals
  183. Penney JB, Young AB. GABA as the pallidothalamic neurotransmitter: implications for basal ganglia function. Brain Res. 1981 Feb 23; 207(1):195-9. PMID: 6258730.
    Citations: 16     Fields:    Translation:AnimalsCells
  184. Snyder SH, Enna SJ, Young AB. Brain mechanisms associated with therapeutic actions of benzodiazepines: focus on neurotransmitters. Am J Psychiatry. 1977 Jun; 134(6):662-5. PMID: 17304.
    Citations: 7     Fields:    Translation:HumansCells
  185. Zukin SR, Young AB, Snyder SH. Development of the synaptic glycine receptor in chick embryo spinal cord. Brain Res. 1975 Jan 17; 83(3):525-30. PMID: 163119.
    Citations: 2     Fields:    Translation:AnimalsCells
  186. Zukin SR, Young AB, Snyder SH. Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system. Proc Natl Acad Sci U S A. 1974 Dec; 71(12):4802-7. PMID: 4155072; PMCID: PMC433985.
    Citations: 93     Fields:    Translation:AnimalsCells
  187. Young AB, Snyder SH. The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism. Proc Natl Acad Sci U S A. 1974 Oct; 71(10):4002-5. PMID: 4372600; PMCID: PMC434315.
    Citations: 18     Fields:    Translation:AnimalsCells
  188. Young AB, Oster-Granite ML, Herndon RM, Snyder SH. Glutamic acid: selective depletion by viral induced granule cell loss in hamster cerebellum. Brain Res. 1974 Jun 14; 73(1):1-13. PMID: 4152168.
    Citations: 32     Fields:    Translation:AnimalsCells
  189. Young AB, Zukin SR, Snyder SH. Interaction of benzodiazepines with central nervous glycine receptors: possible mechanism of action. Proc Natl Acad Sci U S A. 1974 Jun; 71(6):2246-50. PMID: 4152296; PMCID: PMC388428.
    Citations: 27     Fields:    Translation:AnimalsCells
  190. Snyder SH, Young AB, Bennett JP, Mulder AH. Synaptic biochemistry of amino acids. Fed Proc. 1973 Oct; 32(10):2039-47. PMID: 4355732.
    Citations: 24     Fields:    Translation:AnimalsCells
  191. Young AB, Snyder SH. Strychnine binding associated with glycine receptors of the central nervous system. Proc Natl Acad Sci U S A. 1973 Oct; 70(10):2832-6. PMID: 4200724; PMCID: PMC427119.
    Citations: 84     Fields:    Translation:AnimalsCells
  192. Young AB, Snyder SH. A sensitive specific enzymatic-fluorometric assay for homocarnosine. J Neurochem. 1973 Aug; 21(2):387-96. PMID: 4724325.
    Citations:    Fields:    Translation:AnimalsCells