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Tong Sun, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jiang CB, Wang J, Zheng ZX, Hou JS, Ma L, Sun T. [Efficacy of cervical fixed-point traction manipulation for cervical spondylotic radiculopathy: a randomized controlled trial]. Zhong Xi Yi Jie He Xue Bao. 2012 Jan; 10(1):54-8. PMID: 22237275.
    Citations: 1     Fields:    Translation:Humans
  2. Meng H, Xing G, Blanco E, Song Y, Zhao L, Sun B, Li X, Wang PC, Korotcov A, Li W, Liang XJ, Chen C, Yuan H, Zhao F, Chen Z, Sun T, Chai Z, Ferrari M, Zhao Y. Gadolinium metallofullerenol nanoparticles inhibit cancer metastasis through matrix metalloproteinase inhibition: imprisoning instead of poisoning cancer cells. Nanomedicine. 2012 Feb; 8(2):136-46. PMID: 21930111.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  3. Sun T, Oh WK, Jacobus S, Regan M, Pomerantz M, Freedman ML, Lee GS, Kantoff PW. The impact of common genetic variations in genes of the sex hormone metabolic pathways on steroid hormone levels and prostate cancer aggressiveness. Cancer Prev Res (Phila). 2011 Dec; 4(12):2044-50. PMID: 21900597.
    Citations: 10     Fields:    Translation:Humans
  4. Li H, Zhou YF, Guo HY, Sun T, Zhang WH, Lin DX. [Association between CTLA-4 gene polymorphism and susceptibility to cervical cancer]. Zhonghua Zhong Liu Za Zhi. 2011 Sep; 33(9):681-4. PMID: 22340049.
    Citations: 2     Fields:    Translation:Humans
  5. Ma F, Xu B, Lin D, Sun T, Shi Y. [Effect of rs2293347 Polymorphism in EGFR on the Clinical Efficacy of Gefitinib ?in Patients with Non-small Cell Lung Cancer]. Zhongguo Fei Ai Za Zhi. 2011 Aug; 14(8):642-5. PMID: 21859544.
    Citations: 3     Fields:    Translation:Humans
  6. Yang M, Xie W, Mostaghel E, Nakabayashi M, Werner L, Sun T, Pomerantz M, Freedman M, Ross R, Regan M, Sharifi N, Figg WD, Balk S, Brown M, Taplin ME, Oh WK, Lee GS, Kantoff PW. SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer. J Clin Oncol. 2011 Jun 20; 29(18):2565-73. PMID: 21606417.
    Citations: 59     Fields:    Translation:Humans
  7. Pomerantz MM, Werner L, Xie W, Regan MM, Lee GS, Sun T, Evan C, Petrozziello G, Nakabayashi M, Oh WK, Kantoff PW, Freedman ML. Association of prostate cancer risk Loci with disease aggressiveness and prostate cancer-specific mortality. Cancer Prev Res (Phila). 2011 May; 4(5):719-28. PMID: 21367958.
    Citations: 22     Fields:    Translation:Humans
  8. Zhang BL, Sun T, Zhang BN, Zheng S, Lü N, Xu BH, Wang X, Chen GJ, Yu DK, Lin DX. Polymorphisms of GSTP1 is associated with differences of chemotherapy response and toxicity in breast cancer. Chin Med J (Engl). 2011 Jan; 124(2):199-204. PMID: 21362365.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  9. Sun T, Mary LG, Oh WK, Freedman ML, Pomerantz M, Pienta KJ, Kantoff PW. Inherited variants in the chemokine CCL2 gene and prostate cancer aggressiveness in a Caucasian cohort. Clin Cancer Res. 2011 Mar 15; 17(6):1546-52. PMID: 21135144.
    Citations: 8     Fields:    Translation:Humans
  10. Sun T, Lee GS, Oh WK, Pomerantz M, Yang M, Xie W, Freedman ML, Kantoff PW. Single-nucleotide polymorphisms in p53 pathway and aggressiveness of prostate cancer in a Caucasian population. Clin Cancer Res. 2010 Nov 01; 16(21):5244-51. PMID: 20855462.
    Citations: 16     Fields:    Translation:HumansCells
  11. Sun T, Lee GS, Werner L, Pomerantz M, Oh WK, Kantoff PW, Freedman ML. Inherited variations in AR, ESR1, and ESR2 genes are not associated with prostate cancer aggressiveness or with efficacy of androgen deprivation therapy. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1871-8. PMID: 20615892.
    Citations: 10     Fields:    Translation:Humans
  12. Guo Y, Zhang X, Yang M, Miao X, Shi Y, Yao J, Tan W, Sun T, Zhao D, Yu D, Liu J, Lin D. Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer. J Med Genet. 2010 Sep; 47(9):616-22. PMID: 20516147.
    Citations: 19     Fields:    Translation:HumansCells
  13. Zhang L, Yang M, Bi N, Fang M, Sun T, Ji W, Tan W, Zhao L, Yu D, Lin D, Wang L. ATM polymorphisms are associated with risk of radiation-induced pneumonitis. Int J Radiat Oncol Biol Phys. 2010 Aug 01; 77(5):1360-8. PMID: 20171797.
    Citations: 28     Fields:    Translation:HumansCells
  14. Sun T, Yang M, Kantoff P, Lee GS. Role of microRNA-221/-222 in cancer development and progression. . 2009 Aug; 8(15):2315-6. PMID: 19625765.
    Citations: 15     Translation:Humans
  15. Sun T, Hu Z, Shen H, Lin D. Genetic polymorphisms in cytotoxic T-lymphocyte antigen 4 and cancer: the dialectical nature of subtle human immune dysregulation. Cancer Res. 2009 Aug 01; 69(15):6011-4. PMID: 19638588.
    Citations: 22     Fields:    Translation:Humans
  16. Sun T, Wang Q, Balk S, Brown M, Lee GS, Kantoff P. The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines. Cancer Res. 2009 Apr 15; 69(8):3356-63. PMID: 19351832.
    Citations: 100     Fields:    Translation:HumansCells
  17. Ma F, Sun T, Shi Y, Yu D, Tan W, Yang M, Wu C, Chu D, Sun Y, Xu B, Lin D. Polymorphisms of EGFR predict clinical outcome in advanced non-small-cell lung cancer patients treated with Gefitinib. Lung Cancer. 2009 Oct; 66(1):114-9. PMID: 19201048.
    Citations: 23     Fields:    Translation:Humans
  18. Li H, Guo HY, Sun T, Zhou YF, Lin DX, Zhang WH, Qiao J. [Association between Fas/Fas L genes promoter polymorphisms and pathogenic risk of cervical cancer]. Zhonghua Zhong Liu Za Zhi. 2009 Jan; 31(1):38-41. PMID: 19538867.
    Citations: 11     Fields:    Translation:Humans
  19. Sun T, Zhou Y, Yang M, Hu Z, Tan W, Han X, Shi Y, Yao J, Guo Y, Yu D, Tian T, Zhou X, Shen H, Lin D. Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Res. 2008 Sep 01; 68(17):7025-34. PMID: 18757416.
    Citations: 54     Fields:    Translation:HumansCells
  20. Wang J, Sun T, Yang M, Lin DX, Tan W, Li KJ, Xiao Y. [Association of genetic polymorphisms in selenoprotein GPX1 and TXNRD2 with genetic susceptibility of gastric cancer]. Zhonghua Yu Fang Yi Xue Za Zhi. 2008 Jul; 42(7):511-4. PMID: 19035188.
    Citations: 4     Fields:    Translation:Humans
  21. Yang M, Sun T, Wang L, Yu D, Zhang X, Miao X, Liu J, Zhao D, Li H, Tan W, Lin D. Functional variants in cell death pathway genes and risk of pancreatic cancer. Clin Cancer Res. 2008 May 15; 14(10):3230-6. PMID: 18483392.
    Citations: 36     Fields:    Translation:Humans
  22. Yu D, Zhang X, Liu J, Yuan P, Tan W, Guo Y, Sun T, Zhao D, Yang M, Liu J, Xu B, Lin D. Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis. Clin Cancer Res. 2008 May 01; 14(9):2878-86. PMID: 18451256.
    Citations: 21     Fields:    Translation:HumansCells
  23. Liu JN, Zhang XM, Guo YL, Sun T, Lin DX, Wen T. [Genetic polymorphism in MDM2 is associated with susceptibility to colorectal cancer in a Chinese population]. Zhonghua Zhong Liu Za Zhi. 2008 May; 30(5):335-8. PMID: 18953830.
    Citations: 5     Fields:    Translation:Humans
  24. Yang M, Guo Y, Zhang X, Miao X, Tan W, Sun T, Zhao D, Yu D, Liu J, Lin D. Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. Carcinogenesis. 2007 Sep; 28(9):1996-2001. PMID: 17638920.
    Citations: 30     Fields:    Translation:HumansCells
  25. Sun T, Gao Y, Tan W, Ma S, Shi Y, Yao J, Guo Y, Yang M, Zhang X, Zhang Q, Zeng C, Lin D. A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. Nat Genet. 2007 May; 39(5):605-13. PMID: 17450141.
    Citations: 93     Fields:    Translation:HumansCells
  26. Zhao D, Sun T, Zhang X, Guo Y, Yu D, Yang M, Tan W, Wang G, Lin D. Role of CD14 promoter polymorphisms in Helicobacter pylori infection--related gastric carcinoma. Clin Cancer Res. 2007 Apr 15; 13(8):2362-8. PMID: 17438094.
    Citations: 20     Fields:    Translation:HumansCells
  27. Guo Y, Zhang X, Tan W, Miao X, Sun T, Zhao D, Lin D. Platelet 12-lipoxygenase Arg261Gln polymorphism: functional characterization and association with risk of esophageal squamous cell carcinoma in combination with COX-2 polymorphisms. Pharmacogenet Genomics. 2007 Mar; 17(3):197-205. PMID: 17460548.
    Citations: 14     Fields:    Translation:HumansCells
  28. Looman C, Sun T, Yu Y, Zieba A, Ahgren A, Feinstein R, Forsberg H, Hellberg C, Heldin CH, Zhang XQ, Forsberg-Nilsson K, Khoo N, Fundele R, Heuchel R. An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta. Int J Dev Biol. 2007; 51(5):361-70. PMID: 17616925.
    Citations: 3     Fields:    Translation:AnimalsCells
  29. Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, Shi Y, Tan W, Zhou Y, Zhao D, Zhang X, Guo Y, Lin D. Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer. Carcinogenesis. 2007 May; 28(5):1067-73. PMID: 17183065.
    Citations: 43     Fields:    Translation:HumansCells
  30. Tan W, Wu J, Zhang X, Guo Y, Liu J, Sun T, Zhang B, Zhao D, Yang M, Yu D, Lin D. Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer. Carcinogenesis. 2007 Jun; 28(6):1197-201. PMID: 17151091.
    Citations: 42     Fields:    Translation:HumansCells
  31. Sun T, Gao Y, Tan W, Ma S, Zhang X, Wang Y, Zhang Q, Guo Y, Zhao D, Zeng C, Lin D. Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression. Clin Cancer Res. 2006 Dec 01; 12(23):7009-17. PMID: 17145822.
    Citations: 18     Fields:    Translation:HumansCells
  32. Samanta AK, Lin H, Sun T, Kantarjian H, Arlinghaus RB. Janus kinase 2: a critical target in chronic myelogenous leukemia. Cancer Res. 2006 Jul 01; 66(13):6468-72. PMID: 16818614.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  33. Sun T, Deng WB, Diao HL, Ni H, Bai YY, Ma XH, Xu LB, Yang ZM. Differential expression and regulation of prostaglandin E synthases in the mouse ovary during sexual maturation and luteal development. J Endocrinol. 2006 Apr; 189(1):89-101. PMID: 16614384.
    Citations: 2     Fields:    Translation:AnimalsCells
  34. Zhang XM, Miao XP, Tan W, Sun T, Guo YL, Zhao D, Lin DX. [Genetic polymorphisms in the promoter region of cyclooxygenase-2 and their association with risk of gastric cancer]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Apr; 28(2):119-23. PMID: 16733888.
    Citations: 5     Fields:    Translation:HumansCells
  35. Zhang WJ, Miao XP, Sun T, Zhang XM, Qu SN, Tan W, Xiong P, Zheng R, Lin DX. [Association between genetic polymorphism in STK15 and risk of colorectal cancer in a Chinese population]. Zhonghua Zhong Liu Za Zhi. 2006 Jan; 28(1):43-6. PMID: 16737620.
    Citations: 4     Fields:    Translation:Humans
  36. Zhang X, Miao X, Guo Y, Tan W, Zhou Y, Sun T, Wang Y, Lin D. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat. 2006 Jan; 27(1):110-7. PMID: 16287156.
    Citations: 53     Fields:    Translation:Humans
  37. Zhang XM, Miao XP, Tan W, Qu SN, Sun T, Zhou YF, Lin DX. [Association between genetic polymorphisms in methylentetrahydrofolate reductase and risk of lung cancer]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Dec; 27(6):700-3. PMID: 16447641.
    Citations: 8     Fields:    Translation:Humans
  38. Sun T, Zhou Y, Li H, Han X, Shi Y, Wang L, Miao X, Tan W, Zhao D, Zhang X, Guo Y, Lin D. FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer. J Exp Med. 2005 Oct 03; 202(7):967-74. PMID: 16186185.
    Citations: 39     Fields:    Translation:HumansCells
  39. Feng FY, Liang G, Lu WF, Miao XP, Yu CY, Tan W, Zhou YF, Sun T, Kang B, Zhou T, Pan KF, Zhang L, Lin DX. [Correlation of polymorphisms of UDP-glucuronosyltransferase 1A7 gene to genetic susceptibility of lung cancer]. Ai Zheng. 2005 Sep; 24(9):1085-90. PMID: 16159430.
    Citations: 1     Fields:    Translation:Humans
  40. Yang S, Miao XP, Zhang XM, Sun T, Qu SN, Xiong P, Ye YJ, Guo YL, Tan W, Wang S, Lin DX. [Genetic polymorphisms of apoptosis-associated genes FAS and FASL and risk of colorectal cancer]. Zhonghua Yi Xue Za Zhi. 2005 Aug 10; 85(30):2132-5. PMID: 16313826.
    Citations: 6     Fields:    Translation:Humans
  41. Golemovic M, Verstovsek S, Giles F, Cortes J, Manshouri T, Manley PW, Mestan J, Dugan M, Alland L, Griffin JD, Arlinghaus RB, Sun T, Kantarjian H, Beran M. AMN107, a novel aminopyrimidine inhibitor of Bcr-Abl, has in vitro activity against imatinib-resistant chronic myeloid leukemia. Clin Cancer Res. 2005 Jul 01; 11(13):4941-7. PMID: 16000593.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  42. Lin DX, Sun T. [Prospect of uses of single nucleotide polymorphism in the neoplasm research ]. Zhonghua Zhong Liu Za Zhi. 2005 May; 27(5):257-9. PMID: 15996313.
    Citations:    Fields:    Translation:Humans
  43. Xie Y, Wang Y, Sun T, Wang F, Trostinskaia A, Puscheck E, Rappolee DA. Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells. Mol Reprod Dev. 2005 May; 71(1):1-11. PMID: 15736129.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  44. Tan W, Miao X, Wang L, Yu C, Xiong P, Liang G, Sun T, Zhou Y, Zhang X, Li H, Lin D. Significant increase in risk of gastroesophageal cancer is associated with interaction between promoter polymorphisms in thymidylate synthase and serum folate status. Carcinogenesis. 2005 Aug; 26(8):1430-5. PMID: 15817609.
    Citations: 12     Fields:    Translation:HumansCells
  45. Ewart-Toland A, Dai Q, Gao YT, Nagase H, Dunlop MG, Farrington SM, Barnetson RA, Anton-Culver H, Peel D, Ziogas A, Lin D, Miao X, Sun T, Ostrander EA, Stanford JL, Langlois M, Chan JM, Yuan J, Harris CC, Bowman ED, Clayman GL, Lippman SM, Lee JJ, Zheng W, Balmain A. Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis. 2005 Aug; 26(8):1368-73. PMID: 15802297.
    Citations: 48     Fields:    Translation:HumansAnimals
  46. Zhou Y, Yu C, Miao X, Wang Y, Tan W, Sun T, Zhang X, Xiong P, Lin D. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis. 2005 Jun; 26(6):1117-21. PMID: 15731163.
    Citations: 22     Fields:    Translation:HumansCells
  47. Xie Y, Sun T, Wang QT, Wang Y, Wang F, Puscheck E, Rappolee DA. Acquisition of essential somatic cell cycle regulatory protein expression and implied activity occurs at the second to third cell division in mouse preimplantation embryos. FEBS Lett. 2005 Jan 17; 579(2):398-408. PMID: 15642350.
    Citations: 8     Fields:    Translation:AnimalsCells
  48. Zhang XM, Miao XP, Xiong P, Yu CY, Tan W, Qu SN, Sun T, Zhou YF, Lin DX. [Association of functional polymorphisms in matrix metalloproteinase-2 (MMP-2) and MMP-9 genes with risk of gastric cancer in a Chinese population]. Ai Zheng. 2004 Nov; 23(11):1233-7. PMID: 15522165.
    Citations: 6     Fields:    Translation:Humans
  49. Wang Y, Wang F, Sun T, Trostinskaia A, Wygle D, Puscheck E, Rappolee DA. Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos. Dev Dyn. 2004 Sep; 231(1):72-87. PMID: 15305288.
    Citations: 13     Fields:    Translation:AnimalsCells
  50. Sun T, Miao X, Wang J, Tan W, Zhou Y, Yu C, Lin D. Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma. Carcinogenesis. 2004 Nov; 25(11):2225-30. PMID: 15271856.
    Citations: 18     Fields:    Translation:Humans
  51. Sun T, Miao X, Zhang X, Tan W, Xiong P, Lin D. Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma. J Natl Cancer Inst. 2004 Jul 07; 96(13):1030-6. PMID: 15240787.
    Citations: 59     Fields:    Translation:HumansCells
  52. Linghu H, Xu XR, Mei YY, Tang JY, Tang LD, Sun T. Response of early stage bulky cervical squamous carcinoma to preoperative adjuvant chemotherapy. Chin Med Sci J. 2004 Jun; 19(2):116-9. PMID: 15250247.
    Citations: 2     Fields:    Translation:Humans
  53. Miao X, Sun T, Wang Y, Zhang X, Tan W, Lin D. Functional STK15 Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal squamous cell carcinoma. Cancer Res. 2004 Apr 15; 64(8):2680-3. PMID: 15087379.
    Citations: 21     Fields:    Translation:Humans
  54. Sun T, Li SJ, Diao HL, Teng CB, Wang HB, Yang ZM. Cyclooxygenases and prostaglandin E synthases in the endometrium of the rhesus monkey during the menstrual cycle. Reproduction. 2004 Apr; 127(4):465-73. PMID: 15047937.
    Citations: 6     Fields:    Translation:AnimalsCells
  55. Lou H, Duan Z, Sun T, Huang L. Cleavage of double-stranded DNA by the intrinsic 3'-5' exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. FEMS Microbiol Lett. 2004 Feb 09; 231(1):111-7. PMID: 14769474.
    Citations: 6     Fields:    Translation:Cells
  56. Zhou Y, Yu C, Miao X, Tan W, Liang G, Xiong P, Sun T, Lin D. Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes. Carcinogenesis. 2004 Mar; 25(3):399-404. PMID: 14604886.
    Citations: 27     Fields:    Translation:Humans
  57. Ni H, Sun T, Ma XH, Yang ZM. Expression and regulation of cytosolic prostaglandin E synthase in mouse uterus during the peri-implantation period. Biol Reprod. 2003 Mar; 68(3):744-50. PMID: 12604621.
    Citations: 5     Fields:    Translation:AnimalsCells
  58. Ni H, Sun T, Ding NZ, Ma XH, Yang ZM. Differential expression of microsomal prostaglandin e synthase at implantation sites and in decidual cells of mouse uterus. Biol Reprod. 2002 Jul; 67(1):351-8. PMID: 12080039.
    Citations: 12     Fields:    Translation:AnimalsCells
  59. Chen C, Petitclerc E, Zhou H, Brooks PC, Sun T, Yu MC, Zheng W, Dubeau L. Effect of reproductive hormones on ovarian epithelial tumors: II. Effect on angiogenic activity. . 2002 May-Jun; 1(3):307-12. PMID: 12432284.
    Citations: 1     Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.