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Amir Tirosh, Ph.D., M.D.

Other Positions

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kaplan A, Zelicha H, Tsaban G, Yaskolka Meir A, Rinott E, Kovsan J, Novack L, Thiery J, Ceglarek U, Burkhardt R, Willenberg A, Tirosh A, Cabantchik I, Stampfer MJ, Shai I. Protein bioavailability of Wolffia globosa duckweed, a novel aquatic plant, - A randomized controlled trial. Clin Nutr. 2018 Dec 11. PMID: 30591380.
    Citations:    Fields:    
  2. Twig G, Tirosh A, Derazne E, Haklai Z, Goldberger N, Afek A, Gerstein HC, Kark JD, Cukierman-Yaffe T. Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood. Cardiovasc Diabetol. 2018 12 05; 17(1):154. PMID: 30518353.
  3. Polak R, Tirosh A, Livingston B, Pober D, Eubanks JE, Silver JK, Minezaki K, Loten R, Phillips EM. Preventing Type 2 Diabetes with Home Cooking: Current Evidence and Future Potential. Curr Diab Rep. 2018 Sep 14; 18(10):99. PMID: 30218282.
    Citations:    Fields:    
  4. Furer A, Afek A, Orr O, Gershovitz L, Landau Rabbi M, Derazne E, Pinhas-Hamiel O, Fink N, Leiba A, Tirosh A, Kark JD, Twig G. Sex-specific associations between adolescent categories of BMI with cardiovascular and non-cardiovascular mortality in midlife. Cardiovasc Diabetol. 2018 06 05; 17(1):80. PMID: 29871640.
    Citations: 1     Fields:    Translation:Humans
  5. Jenkins A, Lengyel I, Rutter GA, Lowe N, Shai I, Tirosh A, Petro T, Khamaisi M, Andrews S, Zmora N, Gross A, Maret W, Lewis EC, Moran A. Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28-30, 2016 - Israel. J Trace Elem Med Biol. 2018 09; 49:79-85. PMID: 29895375.
    Citations:    Fields:    Translation:Humans
  6. Pinhas-Hamiel O, Reichman B, Shina A, Derazne E, Tzur D, Yifrach D, Wiser I, Afek A, Shamis A, Tirosh A, Twig G. Sex Differences in the Impact of Thinness, Overweight, Obesity, and Parental Height on Adolescent Height. J Adolesc Health. 2017 Aug; 61(2):233-239. PMID: 28457687.
    Citations: 1     Fields:    Translation:Humans
  7. Twig G, Tirosh A, Leiba A, Levine H, Ben-Ami Shor D, Derazne E, Haklai Z, Goldberger N, Kasher-Meron M, Yifrach D, Gerstein HC, Kark JD. BMI at Age 17 Years and Diabetes Mortality in Midlife: A Nationwide Cohort of 2.3 Million Adolescents. Diabetes Care. 2016 Nov; 39(11):1996-2003. PMID: 27733421.
    Citations: 3     Fields:    Translation:Humans
  8. Twig G, Gerstein HC, Fruchter E, Shina A, Afek A, Derazne E, Tzur D, Cukierman-Yaffe T, Amital D, Amital H, Tirosh A. Self-Perceived Emotional Distress and Diabetes Risk Among Young Men. Am J Prev Med. 2016 06; 50(6):737-745. PMID: 26810356.
    Citations:    Fields:    Translation:Humans
  9. Burak MF, Inouye KE, White A, Lee A, Tuncman G, Calay ES, Sekiya M, Tirosh A, Eguchi K, Birrane G, Lightwood D, Howells L, Odede G, Hailu H, West S, Garlish R, Neale H, Doyle C, Moore A, Hotamisligil GS. Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med. 2015 Dec 23; 7(319):319ra205. PMID: 26702093.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  10. Twig G, Shina A, Afek A, Derazne E, Tzur D, Cukierman-Yaffe T, Shechter-Amir D, Gerstein HC, Tirosh A. Sleep quality and risk of diabetes and coronary artery disease among young men. Acta Diabetol. 2016 Apr; 53(2):261-70. PMID: 26077170.
    Citations: 4     Fields:    Translation:Humans
  11. Twig G, Gerstein HC, Ben-Ami Shor D, Derazne E, Tzur D, Afek A, Tirosh A. Coronary artery disease risk among obese metabolically healthy young men. Eur J Endocrinol. 2015 Sep; 173(3):305-12. PMID: 26041076.
    Citations: 2     Fields:    Translation:Humans
  12. Tirosh A, de Souza RJ, Sacks F, Bray GA, Smith SR, LeBoff MS. Sex Differences in the Effects of Weight Loss Diets on Bone Mineral Density and Body Composition: POUNDS LOST Trial. J Clin Endocrinol Metab. 2015 Jun; 100(6):2463-71. PMID: 25825948; PMCID: PMC4454797.
    Citations: 7     Fields:    Translation:Humans
  13. Twig G, Afek A, Derazne E, Tzur D, Cukierman-Yaffe T, Gerstein HC, Tirosh A. Diabetes risk among overweight and obese metabolically healthy young adults. Diabetes Care. 2014 Nov; 37(11):2989-95. PMID: 25139886.
    Citations: 13     Fields:    Translation:Humans
  14. Twig G, Gluzman I, Tirosh A, Gerstein HC, Yaniv G, Afek A, Derazne E, Tzur D, Karasik A, Gordon B, Fruchter E, Lubin G, Rudich A, Cukierman-Yaffe T. Cognitive function and the risk for diabetes among young men. Diabetes Care. 2014 Nov; 37(11):2982-8. PMID: 25092683.
    Citations: 5     Fields:    Translation:Humans
  15. Vivante A, Twig G, Tirosh A, Skorecki K, Calderon-Margalit R. Childhood history of resolved glomerular disease and risk of hypertension during adulthood. JAMA. 2014 Mar 19; 311(11):1155-7. PMID: 24643607.
    Citations: 2     Fields:    Translation:Humans
  16. Twig G, Afek A, Shamiss A, Derazne E, Landau Rabbi M, Tzur D, Gordon B, Tirosh A. Adolescence BMI and trends in adulthood mortality: a study of 2.16 million adolescents. J Clin Endocrinol Metab. 2014 Jun; 99(6):2095-103. PMID: 24601695.
    Citations: 5     Fields:    Translation:Humans
  17. Zada G, Tirosh A, Huang AP, Laws ER, Woodmansee WW. The postoperative cortisol stress response following transsphenoidal pituitary surgery: a potential screening method for assessing preserved pituitary function. Pituitary. 2013 Sep; 16(3):319-25. PMID: 22915289.
    Citations:    Fields:    Translation:Humans
  18. Tirosh A, Golan R, Harman-Boehm I, Henkin Y, Schwarzfuchs D, Rudich A, Kovsan J, Fiedler GM, Blüher M, Stumvoll M, Thiery J, Stampfer MJ, Shai I. Renal function following three distinct weight loss dietary strategies during 2 years of a randomized controlled trial. Diabetes Care. 2013 Aug; 36(8):2225-32. PMID: 23690533; PMCID: PMC3714527.
    Citations: 17     Fields:    Translation:Humans
  19. Twig G, Livneh A, Vivante A, Afek A, Shamiss A, Derazne E, Tzur D, Ben-Zvi I, Tirosh A, Barchana M, Shohat T, Golan E, Amital H. Mortality risk factors associated with familial Mediterranean fever among a cohort of 1.25 million adolescents. Ann Rheum Dis. 2014 Apr; 73(4):704-9. PMID: 23505237; PMCID: PMC4934385.
    Citations: 10     Fields:    Translation:Humans
  20. Vivante A, Golan E, Tzur D, Leiba A, Tirosh A, Skorecki K, Calderon-Margalit R. Body mass index in 1.2 million adolescents and risk for end-stage renal disease. Arch Intern Med. 2012 Nov 26; 172(21):1644-50. PMID: 23108588; PMCID: PMC4941233.
    Citations: 46     Fields:    Translation:Humans
  21. Twig G, Afek A, Shamiss A, Derazne E, Tzur D, Gordon B, Tirosh A. White blood cell count and the risk for coronary artery disease in young adults. PLoS One. 2012; 7(10):e47183. PMID: 23077568; PMCID: PMC3470580.
    Citations: 9     Fields:    Translation:Humans
  22. Twig G, Afek A, Shamiss A, Derazne E, Tzur D, Gordon B, Tirosh A. White blood cells count and incidence of type 2 diabetes in young men. Diabetes Care. 2013 Feb; 36(2):276-82. PMID: 22961572; PMCID: PMC3554323.
    Citations: 16     Fields:    Translation:Humans
  23. Pereg D, Tirosh A, Elis A, Neuman Y, Mosseri M, Segev D, Lishner M, Hermoni D. Mortality and coronary heart disease in euthyroid patients. Am J Med. 2012 Aug; 125(8):826.e7-12. PMID: 22608790; PMCID: PMC4934377.
    Citations: 4     Fields:    Translation:Humans
  24. Shor R, Tirosh A, Shemesh L, Krakover R, Bar Chaim A, Mor A, Boaz M, Golik A. 25 hydroxyvitamin D levels in patients undergoing coronary artery catheterization. Eur J Intern Med. 2012 Jul; 23(5):470-3. PMID: 22726379.
    Citations: 3     Fields:    Translation:Humans
  25. Golan R, Tirosh A, Schwarzfuchs D, Harman-Boehm I, Thiery J, Fiedler GM, Blüher M, Stumvoll M, Shai I. Dietary intervention induces flow of changes within biomarkers of lipids, inflammation, liver enzymes, and glycemic control. Nutrition. 2012 Feb; 28(2):131-7. PMID: 21820871; PMCID: PMC4935830.
    Citations: 2     Fields:    Translation:Humans
  26. Tirosh A, Shai I, Afek A, Dubnov-Raz G, Ayalon N, Gordon B, Derazne E, Tzur D, Shamis A, Vinker S, Rudich A. Adolescent BMI trajectory and risk of diabetes versus coronary disease. N Engl J Med. 2011 Apr 07; 364(14):1315-25. PMID: 21470009; PMCID: PMC4939259.
    Citations: 121     Fields:    Translation:Humans
  27. Hemi R, Yochananov Y, Barhod E, Kasher-Meron M, Karasik A, Tirosh A, Kanety H. p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance. Diabetes. 2011 Apr; 60(4):1134-45. PMID: 21386087.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  28. Ashwal R, Hemi R, Tirosh A, Gordin R, Yissachar E, Cohen-Dayag A, Rosenberg A, Karasik A, Blüher M, Kanety H. Differential expression of novel adiponectin receptor-1 transcripts in skeletal muscle of subjects with normal glucose tolerance and type 2 diabetes. Diabetes. 2011 Mar; 60(3):936-46. PMID: 21289205.
    Citations: 4     Fields:    Translation:HumansCells
  29. Erez G, Tirosh A, Rudich A, Meiner V, Schwarzfuchs D, Sharon N, Shpitzen S, Blüher M, Stumvoll M, Thiery J, Fiedler GM, Friedlander Y, Leiterstdorf E, Shai I. Phenotypic and genetic variation in leptin as determinants of weight regain. Int J Obes (Lond). 2011 Jun; 35(6):785-792. PMID: 21042325; PMCID: PMC4941231.
    Citations: 16     Fields:    Translation:Humans
  30. Zada G, Tirosh A, Kaiser UB, Laws ER, Woodmansee WW. Cushing's disease and idiopathic intracranial hypertension: case report and review of underlying pathophysiological mechanisms. J Clin Endocrinol Metab. 2010 Nov; 95(11):4850-4. PMID: 20739379.
    Citations: 7     Fields:    Translation:Humans
  31. Tirosh A, Garg R, Adler GK. Mineralocorticoid receptor antagonists and the metabolic syndrome. Curr Hypertens Rep. 2010 Aug; 12(4):252-7. PMID: 20563672; PMCID: PMC2948675.
    Citations: 21     Fields:    Translation:HumansCells
  32. Tirosh A, Afek A, Rudich A, Percik R, Gordon B, Ayalon N, Derazne E, Tzur D, Gershnabel D, Grossman E, Karasik A, Shamiss A, Shai I. Progression of normotensive adolescents to hypertensive adults: a study of 26,980 teenagers. Hypertension. 2010 Aug; 56(2):203-9. PMID: 20547973.
    Citations: 32     Fields:    Translation:Humans
  33. Farfel A, Tirosh A, Derazne E, Garty BZ, Afek A. Association between socioeconomic status and the prevalence of asthma. Ann Allergy Asthma Immunol. 2010 Jun; 104(6):490-5. PMID: 20568381.
    Citations: 5     Fields:    Translation:Humans
  34. Shai I, Spence JD, Schwarzfuchs D, Henkin Y, Parraga G, Rudich A, Fenster A, Mallett C, Liel-Cohen N, Tirosh A, Bolotin A, Thiery J, Fiedler GM, Blüher M, Stumvoll M, Stampfer MJ. Dietary intervention to reverse carotid atherosclerosis. Circulation. 2010 Mar 16; 121(10):1200-8. PMID: 20194883.
    Citations: 37     Fields:    Translation:Humans
  35. Stern Z, Calderon-Margalit R, Mazar M, Brezis M, Tirosh A. Emergency room visit: a red-flag indicator for poor diabetes care. Diabet Med. 2009 Nov; 26(11):1105-11. PMID: 19929988.
    Citations: 4     Fields:    Translation:Humans
  36. Tirosh A, Shai I, Bitzur R, Kochba I, Tekes-Manova D, Israeli E, Shochat T, Rudich A. Changes in triglyceride levels over time and risk of type 2 diabetes in young men. Diabetes Care. 2008 Oct; 31(10):2032-7. PMID: 18591400; PMCID: PMC2551650.
    Citations: 33     Fields:    Translation:Humans
  37. Elis A, Pereg D, Tirosh A, Shochat T, Tekes-Manova D, Lishner M. Family history of cardiovascular disease does not predict risk-reducing behavior. Eur J Cardiovasc Prev Rehabil. 2008 Jun; 15(3):325-8. PMID: 18525388.
    Citations: 4     Fields:    Translation:Humans
  38. Pereg D, Tirosh A, Lishner M, Goldberg A, Shochat T, Confino-Cohen R. Prevalence of asthma in a large group of Israeli adolescents: influence of country of birth and age at migration. Allergy. 2008 Aug; 63(8):1040-5. PMID: 18384451.
    Citations: 6     Fields:    Translation:Humans
  39. Pereg D, Tirosh A, Shochat T, Hasdai D. Mild renal dysfunction associated with incident coronary artery disease in young males. Eur Heart J. 2008 Jan; 29(2):198-203. PMID: 18079138.
    Citations:    Fields:    Translation:Humans
  40. Tirosh A, Rudich A, Shochat T, Tekes-Manova D, Israeli E, Henkin Y, Kochba I, Shai I. Changes in triglyceride levels and risk for coronary heart disease in young men. Ann Intern Med. 2007 Sep 18; 147(6):377-85. PMID: 17876021.
    Citations: 40     Fields:    Translation:Humans
  41. Israeli E, Korzets Z, Tekes-Manova D, Tirosh A, Schochat T, Bernheim J, Golan E. Blood-pressure categories in adolescence predict development of hypertension in accordance with the European guidelines. Am J Hypertens. 2007 Jun; 20(6):705-9. PMID: 17531932.
    Citations: 7     Fields:    Translation:Humans
  42. Heymann AD, Shilo Y, Tirosh A, Valinsky L, Vinker S. Differences between soldiers, with and without emotional distress, in number of primary care medical visits and type of presenting complaints. Isr Med Assoc J. 2007 Feb; 9(2):90-3. PMID: 17348479.
    Citations:    Fields:    Translation:Humans
  43. Tirosh A, Mandel D, Mimouni FB, Zimlichman E, Shochat T, Kochba I. Autoimmune diseases in asthma. Ann Intern Med. 2006 Jun 20; 144(12):877-83. PMID: 16785476.
    Citations: 13     Fields:    Translation:HumansCells
  44. Tirosh A, Shai I, Tekes-Manova D, Israeli E, Pereg D, Shochat T, Kochba I, Rudich A. Normal fasting plasma glucose levels and type 2 diabetes in young men. N Engl J Med. 2005 Oct 06; 353(14):1454-62. PMID: 16207847.
    Citations: 102     Fields:    Translation:Humans
  45. Pereg D, Kimhi O, Tirosh A, Orr N, Kayouf R, Lishner M. The effect of fermented yogurt on the prevention of diarrhea in a healthy adult population. Am J Infect Control. 2005 Mar; 33(2):122-5. PMID: 15761413.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  46. Ben-Romano R, Rudich A, Tirosh A, Potashnik R, Sasaoka T, Riesenberg K, Schlaeffer F, Bashan N. Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-zeta. Diabetologia. 2004 Jun; 47(6):1107-17. PMID: 15168016.
    Citations: 15     Fields:    Translation:AnimalsCells
  47. Rudich A, Vanounou S, Riesenberg K, Porat M, Tirosh A, Harman-Boehm I, Greenberg AS, Schlaeffer F, Bashan N. The HIV protease inhibitor nelfinavir induces insulin resistance and increases basal lipolysis in 3T3-L1 adipocytes. Diabetes. 2001 Jun; 50(6):1425-31. PMID: 11375344.
    Citations: 16     Fields:    Translation:AnimalsCells
  48. Tirosh A, Rudich A, Potashnik R, Bashan N. Oxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytes. Biochem J. 2001 May 01; 355(Pt 3):757-63. PMID: 11311139; PMCID: PMC1221792.
    Citations: 8     Fields:    Translation:AnimalsCells
  49. Talmor D, Applebaum A, Rudich A, Shapira Y, Tirosh A. Activation of mitogen-activated protein kinases in human heart during cardiopulmonary bypass. Circ Res. 2000 May 12; 86(9):1004-7. PMID: 10807874.
    Citations: 12     Fields:    Translation:HumansCells
  50. Tirosh A, Rudich A, Bashan N. Regulation of glucose transporters--implications for insulin resistance states. J Pediatr Endocrinol Metab. 2000 Feb; 13(2):115-33. PMID: 10711656.
    Citations: 1     Fields:    Translation:Humans
  51. Rudich A, Tirosh A, Potashnik R, Khamaisi M, Bashan N. Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes. Diabetologia. 1999 Aug; 42(8):949-57. PMID: 10491755.
    Citations: 26     Fields:    Translation:AnimalsCells
  52. Tirosh A, Potashnik R, Bashan N, Rudich A. Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. J Biol Chem. 1999 Apr 09; 274(15):10595-602. PMID: 10187855.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  53. Rudich A, Tirosh A, Potashnik R, Hemi R, Kanety H, Bashan N. Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes. Diabetes. 1998 Oct; 47(10):1562-9. PMID: 9753293.
    Citations: 91     Fields:    Translation:AnimalsCells
  54. Khamaisi M, Potashnik R, Tirosh A, Demshchak E, Rudich A, Tritschler H, Wessel K, Bashan N. Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats. Metabolism. 1997 Jul; 46(7):763-8. PMID: 9225829.
    Citations: 14     Fields:    Translation:Animals
  55. Tirosh A, Anaise JZ. Prevalence of caries and periodontal disease and oral hygiene status in urban teenagers (15--17 years of age). Refuat Hapeh Vehashinayim. 1979 Jan; 28(1):39-44, 35-9. PMID: 289638.
    Citations:    Fields:    Translation:HumansPHPublic Health
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.