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profileStephen Neil Gomperts, M.D., Ph.D.

TitleAssistant Professor of Neurology
InstitutionMassachusetts General Hospital
DepartmentNeurology
AddressMassachusetts General Hospital
Cny 2004
114 16th Street
Charlestown MA 02129
Phone617/726-2000
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R21NS090243     (GOMPERTS, STEPHEN N.)Sep 15, 2014 - Aug 31, 2016
NIH/NINDS
PET imaging of hyperphosphorylated tau differentiates PSP and CBD from PD
Role: Principal Investigator

K08MH081027     (GOMPERTS, STEPHEN N.)Jun 1, 2008 - Nov 30, 2013
NIH/NIMH
Ventral Tegmental Area and Hippocampal Interactions in Reinforced Spatial Learnin
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. 2017 Jun 07. PMID: 28592453.
    View in: PubMed
  2. Xia C, Makaretz SJ, Caso C, McGinnis S, Gomperts SN, Sepulcre J, Gomez-Isla T, Hyman BT, Schultz A, Vasdev N, Johnson KA, Dickerson BC. Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease. JAMA Neurol. 2017 Apr 01; 74(4):427-436. PMID: 28241163.
    View in: PubMed
  3. Marquié M, Normandin MD, Meltzer AC, Siao Tick Chong M, Andrea NV, Antón-Fernández A, Klunk WE, Mathis CA, Ikonomovic MD, Debnath M, Bien EA, Vanderburg CR, Costantino I, Makaretz S, DeVos SL, Oakley DH, Gomperts SN, Growdon JH, Domoto-Reilly K, Lucente D, Dickerson BC, Frosch MP, Hyman BT, Johnson KA, Gómez-Isla T. Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies. Ann Neurol. 2017 Jan; 81(1):117-128. PMID: 27997036.
    View in: PubMed
  4. Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. JAMA Neurol. 2016 Nov 01; 73(11):1334-1341. PMID: 27654968.
    View in: PubMed
  5. Gomperts SN. Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia. Continuum (Minneap Minn). 2016 Apr; 22(2 Dementia):435-63. PMID: 27042903.
    View in: PubMed
  6. Gomperts SN, Marquie M, Locascio JJ, Bayer S, Johnson KA, Growdon JH. PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies. Neurodegener Dis. 2016; 16(1-2):118-24. PMID: 26655867; PMCID: PMC4838335 [Available on 01/01/17].
  7. Gomperts SN, Kloosterman F, Wilson MA. VTA neurons coordinate with the hippocampal reactivation of spatial experience. Elife. 2015 Oct 14; 4. PMID: 26465113; PMCID: PMC4695386.
  8. Marquié M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG, Klunk WE, Mathis CA, Ikonomovic MD, Debnath ML, Vasdev N, Dickerson BC, Gomperts SN, Growdon JH, Johnson KA, Frosch MP, Hyman BT, Gómez-Isla T. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov; 78(5):787-800. PMID: 26344059; PMCID: PMC4900162 [Available on 11/01/16].
  9. Rieckmann A, Gomperts SN, Johnson KA, Growdon JH, Van Dijk KR. Putamen-midbrain functional connectivity is related to striatal dopamine transporter availability in patients with Lewy body diseases. Neuroimage Clin. 2015; 8:554-9. PMID: 26137443; PMCID: PMC4484547.
  10. Marquie M, Locascio JJ, Rentz DM, Becker JA, Hedden T, Johnson KA, Growdon JH, Gomperts SN. Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an (11)C altropane positron emission tomography study. Alzheimers Res Ther. 2014; 6(5-8):52. PMID: 25429309; PMCID: PMC4245149.
  11. Gomperts SN. Imaging the role of amyloid in PD dementia and dementia with Lewy bodies. Curr Neurol Neurosci Rep. 2014 Aug; 14(8):472. PMID: 25011528.
    View in: PubMed
  12. Chen Z, Gomperts SN, Yamamoto J, Wilson MA. Neural representation of spatial topology in the rodent hippocampus. Neural Comput. 2014 Jan; 26(1):1-39. PMID: 24102128; PMCID: PMC3967246.
  13. Ding H, Dhima K, Lockhart KC, Locascio JJ, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Hayes MT, Sohur US, Wills AM, Mollenhauer B, Flaherty AW, Hung AY, Mejia N, Khurana V, Gomperts SN, Selkoe DJ, Schwarzschild MA, Schlossmacher MG, Hyman BT, Sudarsky LR, Growdon JH, Scherzer CR. Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study. Neurology. 2013 Oct 22; 81(17):1531-7. PMID: 24068787; PMCID: PMC3888173.
  14. Gomperts SN, Johnson KA, Growdon J. Reply: Beyond the limits of detection: failure of PiB imaging to capture true Aß burden. Mov Disord. 2013 Mar; 28(3):407. PMID: 23401107; PMCID: PMC3741662.
  15. Gomperts SN, Locascio JJ, Rentz D, Santarlasci A, Marquie M, Johnson KA, Growdon JH. Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia. Neurology. 2013 Jan 01; 80(1):85-91. PMID: 23243071; PMCID: PMC3589197.
  16. Gomperts SN, Locascio JJ, Marquie M, Santarlasci AL, Rentz DM, Maye J, Johnson KA, Growdon JH. Brain amyloid and cognition in Lewy body diseases. Mov Disord. 2012 Jul; 27(8):965-73. PMID: 22693110; PMCID: PMC3725259.
  17. Nguyen DP, Layton SP, Hale G, Gomperts SN, Davidson TJ, Kloosterman F, Wilson MA. Micro-drive array for chronic in vivo recording: tetrode assembly. J Vis Exp. 2009 Apr 22; (26). PMID: 19387422; PMCID: PMC2794082.
  18. Kloosterman F, Davidson TJ, Gomperts SN, Layton SP, Hale G, Nguyen DP, Wilson MA. Micro-drive array for chronic in vivo recording: drive fabrication. J Vis Exp. 2009 Apr 20; (26). PMID: 19381129; PMCID: PMC2793172.
  19. Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA. Imaging amyloid deposition in Lewy body diseases. Neurology. 2008 Sep 16; 71(12):903-10. PMID: 18794492; PMCID: PMC2637553.
  20. Gomperts SN, Carroll R, Malenka RC, Nicoll RA. Distinct roles for ionotropic and metabotropic glutamate receptors in the maturation of excitatory synapses. J Neurosci. 2000 Mar 15; 20(6):2229-37. PMID: 10704498.
    View in: PubMed
  21. Kalman D, Gomperts SN, Hardy S, Kitamura M, Bishop JM. Ras family GTPases control growth of astrocyte processes. Mol Biol Cell. 1999 May; 10(5):1665-83. PMID: 10233170; PMCID: PMC30489.
  22. Gomperts SN, Rao A, Craig AM, Malenka RC, Nicoll RA. Postsynaptically silent synapses in single neuron cultures. Neuron. 1998 Dec; 21(6):1443-51. PMID: 9883736.
    View in: PubMed
  23. Lissin DV, Gomperts SN, Carroll RC, Christine CW, Kalman D, Kitamura M, Hardy S, Nicoll RA, Malenka RC, von Zastrow M. Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors. Proc Natl Acad Sci U S A. 1998 Jun 09; 95(12):7097-102. PMID: 9618545; PMCID: PMC22752.
  24. Gomperts SN. Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family. Cell. 1996 Mar 08; 84(5):659-62. PMID: 8625403.
    View in: PubMed
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