Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Sharmila Dorbala, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. K24HL157648 (DORBALA, SHARMILA) May 1, 2021 - Apr 30, 2026
    NIH
    Mentoring Patient Oriented Research in Innovative Imaging and High-dimensional Data Approaches to Improve Outcomes in Cardiac Amyloidosis
    Role: Principal Investigator
  2. R01HL150342 (DORBALA, SHARMILA) Mar 1, 2020 - Jan 31, 2024
    NIH
    Early Detection of Transthyretin Cardiac Amyloidosis: Defining a Novel Target for HFpEF Treatment and Prevention in Late Life
    Role: Principal Investigator
  3. R01HL130563 (DORBALA, SHARMILA) Apr 1, 2016 - Mar 31, 2021
    NIH
    Molecular Imaging of Primary Amyloid Cardiomyopathy
    Role: Principal Investigator
  4. K23HL092299 (DORBALA, SHARMILA) Sep 1, 2009 - May 31, 2015
    NIH
    Prognostic Utility of Absolute Coronary Microvascular Function by PET/CT
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weber B, Wallace ZS, Parks S, Cook C, Huck DM, Garshick M, Brown JM, Divakaran S, Hainer J, Dorbala S, Blankstein R, Liao KP, Aghayev A, Choi HK, Di Carli M. Association Between Systemic Vasculitis and Coronary Microvascular Dysfunction in the Absence of Obstructive Coronary Artery Disease. Circ Cardiovasc Imaging. 2023 Jan; 16(1):e014940. PMID: 36649456.
    Citations:    Fields:    
  2. Khor YM, Cuddy SAM, Singh V, Falk RH, Di Carli MF, Dorbala S. 99mTc Bone-Avid Tracer Cardiac Scintigraphy: Role in Noninvasive Diagnosis of Transthyretin Cardiac Amyloidosis. Radiology. 2023 Feb; 306(2):e221082. PMID: 36537896.
    Citations:    Fields:    
  3. Abrahamson EE, Padera RF, Davies J, Farrar G, Villemagne VL, Dorbala S, Ikonomovic MD. The flutemetamol analogue cyano-flutemetamol detects myocardial AL and ATTR amyloid deposits: a post-mortem histofluorescence analysis. Amyloid. 2022 Nov 21; 1-19. PMID: 36411500.
    Citations:    Fields:    
  4. Cuddy SA, Datar Y, Ovsak G, Saith S, Murphy SP, Bay CP, Haddad M, Lilleness B, Muralidhar V, Pipilas A, Vuong J, Guardino E, Maurer MS, Ruberg FL, Falk RH, Dorbala S. Optimal Echocardiographic Parameters to Improve the Diagnostic Yield of Tc-99m-Bone Avid Tracer Cardiac Scintigraphy for Transthyretin Cardiac Amyloidosis. Circ Cardiovasc Imaging. 2022 11; 15(11):e014645. PMID: 36378779; PMCID: PMC9667717.
    Citations:    Fields:    Translation:Humans
  5. Dorbala S. Fibroblast Activation: A Novel Mechanism of Heart Failure in Light Chain Cardiac Amyloidosis? JACC Cardiovasc Imaging. 2022 11; 15(11):1971-1973. PMID: 36357139.
    Citations:    Fields:    Translation:HumansCells
  6. Singh A, Miller RJH, Otaki Y, Kavanagh P, Hauser MT, Tzolos E, Kwiecinski J, Van Kriekinge S, Wei CC, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Huang C, Han D, Dey D, Berman DS, Slomka PJ. Direct Risk Assessment From Myocardial Perfusion Imaging Using Explainable Deep Learning. JACC Cardiovasc Imaging. 2022 Oct 19. PMID: 36274041.
    Citations:    Fields:    
  7. Weber B, Parks S, Huck DM, Kim A, Bay C, Brown JM, Divakaran S, Hainer J, Bibbo C, Taqueti V, Dorbala S, Blankstein R, Woolley AE, Di Carli MF. Prior SARS-CoV-2 Infection Is Associated With Coronary Vasomotor Dysfunction as Assessed by Coronary Flow Reserve From Cardiac Positron Emission Tomography. J Am Heart Assoc. 2022 10 18; 11(20):e025844. PMID: 36250654; PMCID: PMC9673657.
    Citations:    Fields:    Translation:HumansCells
  8. Miller RJH, Singh A, Otaki Y, Tamarappoo BK, Kavanagh P, Parekh T, Hu LH, Gransar H, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli MF, Liang JX, Dey D, Berman DS, Slomka PJ. Mitigating bias in deep learning for diagnosis of coronary artery disease from myocardial perfusion SPECT images. Eur J Nucl Med Mol Imaging. 2023 01; 50(2):387-397. PMID: 36194270.
    Citations:    Fields:    Translation:Humans
  9. Ge Y, Pandya A, Cuddy SAM, Singh A, Singh A, Dorbala S. Modeling the Cost and Health Impacts of Diagnostic Strategies in Patients with Suspected Transthyretin Cardiac Amyloidosis. J Am Heart Assoc. 2022 09 20; 11(18):e026308. PMID: 36102240; PMCID: PMC9683684.
    Citations:    Fields:    Translation:Humans
  10. Brown JM, Zhou W, Weber B, Divakaran S, Barrett L, Bibbo CF, Hainer J, Taqueti VR, Dorbala S, Blankstein R, Di Carli MF. Low coronary flow relative to myocardial mass predicts heart failure in symptomatic hypertensive patients with no obstructive coronary artery disease. Eur Heart J. 2022 09 14; 43(35):3323-3331. PMID: 34491335; PMCID: PMC9470377.
    Citations: 3     Fields:    
  11. Thompson RC, Einstein AJ, Dorbala S, Iskandrian AE. What makes for a great editorial? The Ken Brown JNC Editorial Award. J Nucl Cardiol. 2022 08; 29(4):1498-1499. PMID: 35764776.
    Citations:    Fields:    
  12. Giblin GT, Cuddy SAM, González-López E, Sewell A, Murphy A, Dorbala S, Falk RH. Effect of tafamidis on global longitudinal strain and myocardial work in transthyretin cardiac amyloidosis. Eur Heart J Cardiovasc Imaging. 2022 07 21; 23(8):1029-1039. PMID: 35274130; PMCID: PMC9303005.
    Citations:    Fields:    Translation:Humans
  13. Rios R, Miller RJH, Hu LH, Otaki Y, Singh A, Diniz M, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, DiCarli M, Van Kriekinge S, Kavanagh P, Parekh T, Liang JX, Dey D, Berman DS, Slomka P. Determining a minimum set of variables for machine learning cardiovascular event prediction: results from REFINE SPECT registry. Cardiovasc Res. 2022 07 20; 118(9):2152-2164. PMID: 34259870; PMCID: PMC9302886.
    Citations: 2     Fields:    Translation:Humans
  14. Tamarappoo BK, Otaki Y, Sharir T, Hu LH, Gransar H, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Eisenberg E, Liang JX, Dey D, Berman DS, Slomka PJ. Differences in Prognostic Value of Myocardial Perfusion Single-Photon Emission Computed Tomography Using High-Efficiency Solid-State Detector Between Men and Women in a Large International Multicenter Study. Circ Cardiovasc Imaging. 2022 06; 15(6):e012741. PMID: 35727872; PMCID: PMC9307118.
    Citations:    Fields:    Translation:Humans
  15. de Souza ACDAH, Harms HJ, Martell L, Bibbo C, Harrington M, Sullivan K, Hainer J, Dorbala S, Blankstein R, Taqueti VR, Foley Kijewski M, Park MA, Meretta A, Breault C, Roth N, Poitrasson-Rivière A, Soman P, Gullberg GT, Di Carli MF. Accuracy and Reproducibility of Myocardial Blood Flow Quantification by Single Photon Emission Computed Tomography Imaging in Patients With Known or Suspected Coronary Artery Disease. Circ Cardiovasc Imaging. 2022 06; 15(6):e013987. PMID: 35674051; PMCID: PMC9233115.
    Citations:    Fields:    Translation:Humans
  16. Benz DC, Dorbala S, Pazhenkottil AP. Quantifying the burden of cardiac amyloid: The future is about numbers! J Nucl Cardiol. 2022 Jun 07. PMID: 35672568.
    Citations:    Fields:    
  17. Miller RJH, Hauser MT, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Huang C, Liang JX, Han D, Dey D, Berman DS, Slomka PJ. Machine learning to predict abnormal myocardial perfusion from pre-test features. J Nucl Cardiol. 2022 Oct; 29(5):2393-2403. PMID: 35672567; PMCID: PMC9588501.
    Citations:    Fields:    
  18. Einstein AJ, Hirschfeld C, Williams MC, Vitola JV, Better N, Villines TC, Cerci R, Shaw LJ, Choi AD, Dorbala S, Karthikeyan G, Lu B, Sinitsyn V, Ansheles AA, Kudo T, Bucciarelli-Ducci C, Nørgaard BL, Maurovich-Horvat P, Campisi R, Milan E, Louw L, Allam AH, Bhatia M, Sewanan L, Malkovskiy E, Cohen Y, Randazzo M, Narula J, Morozova O, Pascual TNB, Pynda Y, Dondi M, Paez D. Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19. J Am Coll Cardiol. 2022 05 24; 79(20):2001-2017. PMID: 35589162; PMCID: PMC9109706.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  19. Miller RJH, Kuronuma K, Singh A, Otaki Y, Hayes S, Chareonthaitawee P, Kavanagh P, Parekh T, Tamarappoo BK, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Carli MD, Cadet S, Liang JX, Dey D, Berman DS, Slomka PJ. Explainable Deep Learning Improves Physician Interpretation of Myocardial Perfusion Imaging. J Nucl Med. 2022 11; 63(11):1768-1774. PMID: 35512997; PMCID: PMC9635672.
    Citations:    Fields:    
  20. Akintoye E, Salih M, Aje K, Alvarez P, Sellke F, Briasoulis A, Dorbala S. Trends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation. Can J Cardiol. 2022 08; 38(8):1263-1270. PMID: 35525397.
    Citations:    Fields:    
  21. Thompson RC, Phillips LM, Dilsizian V, Gutierrez DP, Einstein AJ, Crews SF, Skali H, Jih FKY, Dondi