Harvard Catalyst Profiles

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Ole V. Gjoerup, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kim JW, Berrios C, Kim M, Schade AE, Adelmant G, Yeerna H, Damato E, Iniguez AB, Florens L, Washburn MP, Stegmaier K, Gray NS, Tamayo P, Gjoerup O, Marto JA, DeCaprio J, Hahn WC. STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. Elife. 2020 Jan 08; 9. PMID: 31913126.
    Citations:    
  2. Hwang JH, Seo JH, Beshiri ML, Wankowicz S, Liu D, Cheung A, Li J, Qiu X, Hong AL, Botta G, Golumb L, Richter C, So J, Sandoval GJ, Giacomelli AO, Ly SH, Han C, Dai C, Pakula H, Sheahan A, Piccioni F, Gjoerup O, Loda M, Sowalsky AG, Ellis L, Long H, Root DE, Kelly K, Van Allen EM, Freedman ML, Choudhury AD, Hahn WC. CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell Rep. 2019 11 19; 29(8):2355-2370.e6. PMID: 31747605.
    Citations:    
  3. Hong AL, Tseng YY, Wala JA, Kim WJ, Kynnap BD, Doshi MB, Kugener G, Sandoval GJ, Howard TP, Li J, Yang X, Tillgren M, Ghandi M, Sayeed A, Deasy R, Ward A, McSteen B, Labella KM, Keskula P, Tracy A, Connor C, Clinton CM, Church AJ, Crompton BD, Janeway KA, Van Hare B, Sandak D, Gjoerup O, Bandopadhayay P, Clemons PA, Schreiber SL, Root DE, Gokhale PC, Chi SN, Mullen EA, Roberts CW, Kadoch C, Beroukhim R, Ligon KL, Boehm JS, Hahn WC. Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. Elife. 2019 03 12; 8. PMID: 30860482.
    Citations:    
  4. Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC. An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer. Elife. 2018 07 30; 7. PMID: 30059005.
    Citations:    Fields:    
  5. Shin J, Phelan PJ, Chhum P, Bashkenova N, Yim S, Parker R, Gagnon D, Gjoerup O, Archambault J, Bullock PA. Analysis of JC virus DNA replication using a quantitative and high-throughput assay. Virology. 2014 Nov; 468-470:113-125. PMID: 25155200.
    Citations: 1     Fields:    Translation:HumansCells
  6. Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN. Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase. J Immunol. 2014 Jun 15; 192(12):5933-42. PMID: 24799566.
    Citations: 11     Fields:    Translation:HumansCells
  7. Banerjee P, DeJesus R, Gjoerup O, Schaffhausen BS. Viral interference with DNA repair by targeting of the single-stranded DNA binding protein RPA. PLoS Pathog. 2013 Oct; 9(10):e1003725. PMID: 24204272.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  8. Hu L, Filippakis H, Huang H, Yen TJ, Gjoerup OV. Replication stress and mitotic dysfunction in cells expressing simian virus 40 large T antigen. J Virol. 2013 Dec; 87(24):13179-92. PMID: 24067972.
    Citations: 8     Fields:    Translation:HumansCells
  9. Watanabe M, Phamduong E, Huang CH, Itoh N, Bernal J, Nakanishi A, Rundell K, Gjoerup O, Kasamatsu H. Formation of covalently modified folding intermediates of simian virus 40 Vp1 in large T antigen-expressing cells. J Virol. 2013 May; 87(9):5053-64. PMID: 23427157.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Boichuk S, Hu L, Makielski K, Pandolfi PP, Gjoerup OV. Functional connection between Rad51 and PML in homology-directed repair. PLoS One. 2011; 6(10):e25814. PMID: 21998700.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  11. Kucharski TJ, Gamache I, Gjoerup O, Teodoro JG. DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin. J Virol. 2011 Dec; 85(23):12638-49. PMID: 21937663.
    Citations: 10     Fields:    Translation:HumansCells
  12. Feng H, Kwun HJ, Liu X, Gjoerup O, Stolz DB, Chang Y, Moore PS. Cellular and viral factors regulating Merkel cell polyomavirus replication. PLoS One. 2011; 6(7):e22468. PMID: 21799863.
    Citations: 36     Fields:    Translation:HumansCells
  13. Liu X, Hein J, Richardson SC, Basse PH, Toptan T, Moore PS, Gjoerup OV, Chang Y. Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus. J Biol Chem. 2011 May 13; 286(19):17079-90. PMID: 21454559.
    Citations: 21     Fields:    Translation:HumansCells
  14. Boichuk S, Hu L, Hein J, Gjoerup OV. Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen. J Virol. 2010 Aug; 84(16):8007-20. PMID: 20519379.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  15. Gjoerup O, Chang Y. Update on human polyomaviruses and cancer. Adv Cancer Res. 2010; 106:1-51. PMID: 20399955.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  16. Shuda M, Arora R, Kwun HJ, Feng H, Sarid R, Fern√°ndez-Figueras MT, Tolstov Y, Gjoerup O, Mansukhani MM, Swerdlow SH, Chaudhary PM, Kirkwood JM, Nalesnik MA, Kant JA, Weiss LM, Moore PS, Chang Y. Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors. Int J Cancer. 2009 Sep 15; 125(6):1243-9. PMID: 19499546.
    Citations: 103     Fields:    Translation:HumansCells
  17. Cheng H, Liu P, Wang ZC, Zou L, Santiago S, Garbitt V, Gjoerup OV, Iglehart JD, Miron A, Richardson AL, Hahn WC, Zhao JJ. SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis. Sci Signal. 2009 Jul 21; 2(80):ra35. PMID: 19622832.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  18. Hein J, Boichuk S, Wu J, Cheng Y, Freire R, Jat PS, Roberts TM, Gjoerup OV. Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding. J Virol. 2009 Jan; 83(1):117-27. PMID: 18922873.
    Citations: 47     Fields:    Translation:HumansCells
  19. Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS, Chang Y. T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42):16272-7. PMID: 18812503.
    Citations: 194     Fields:    Translation:HumansCells
  20. Andrabi S, Gjoerup OV, Kean JA, Roberts TM, Schaffhausen B. Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):19011-6. PMID: 18006659.
    Citations: 36     Fields:    Translation:AnimalsCells
  21. Lock RL, Szeto TH, Entwistle A, Gjoerup OV, Jat PS. Preparation of monoclonal antibodies against the spindle checkpoint kinase Bub1. Hybridoma (Larchmt). 2007 Jun; 26(3):140-7. PMID: 17600495.
    Citations:    Fields:    Translation:AnimalsCells
  22. Williams GL, Roberts TM, Gjoerup OV. Bub1: escapades in a cellular world. Cell Cycle. 2007 Jul 15; 6(14):1699-704. PMID: 17643075.
    Citations: 15     Fields:    Translation:HumansCells
  23. Gjoerup OV, Wu J, Chandler-Militello D, Williams GL, Zhao J, Schaffhausen B, Jat PS, Roberts TM. Surveillance mechanism linking Bub1 loss to the p53 pathway. Proc Natl Acad Sci U S A. 2007 May 15; 104(20):8334-9. PMID: 17488820.
    Citations: 25     Fields:    Translation:HumansCells
  24. Zhao JJ, Cheng H, Jia S, Wang L, Gjoerup OV, Mikami A, Roberts TM. The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16296-300. PMID: 17060635.
    Citations: 80     Fields:    Translation:AnimalsCells
  25. Kaur R, Liu X, Gjoerup O, Zhang A, Yuan X, Balk SP, Schneider MC, Lu ML. Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase. J Biol Chem. 2005 Feb 04; 280(5):3323-30. PMID: 15550393.
    Citations: 17     Fields:    Translation:HumansCells
  26. Zhang L, Gjoerup O, Roberts TM. The serine/threonine kinase cyclin G-associated kinase regulates epidermal growth factor receptor signaling. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10296-301. PMID: 15240878.
    Citations: 24     Fields:    Translation:HumansCells
  27. Cotsiki M, Lock RL, Cheng Y, Williams GL, Zhao J, Perera D, Freire R, Entwistle A, Golemis EA, Roberts TM, Jat PS, Gjoerup OV. Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):947-52. PMID: 14732683.
    Citations: 39     Fields:    Translation:AnimalsCells
  28. Zhao JJ, Gjoerup OV, Subramanian RR, Cheng Y, Chen W, Roberts TM, Hahn WC. Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase. Cancer Cell. 2003 May; 3(5):483-95. PMID: 12781366.
    Citations: 108     Fields:    Translation:HumansCells
  29. Gjoerup O, Zaveri D, Roberts TM. Induction of p53-independent apoptosis by simian virus 40 small t antigen. J Virol. 2001 Oct; 75(19):9142-55. PMID: 11533178.
    Citations: 18     Fields:    Translation:HumansCells
  30. Grammatikakis N, Jaronczyk K, Siganou A, Vultur A, Brownell HL, Benzaquen M, Rausch C, Lapointe R, Gjoerup O, Roberts TM, Raptis L. Simian virus 40 large tumor antigen modulates the Raf signaling pathway. J Biol Chem. 2001 Jul 27; 276(30):27840-5. PMID: 11382757.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  31. Gjoerup O, Chao H, DeCaprio JA, Roberts TM. pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression. J Virol. 2000 Jan; 74(2):864-74. PMID: 10623749.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  32. Jun T, Gjoerup O, Roberts TM. Tangled webs: evidence of cross-talk between c-Raf-1 and Akt. Sci STKE. 1999 Dec 21; 1999(13):PE1. PMID: 11865188.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  33. Holman PS, Gjoerup OV, Davin T, Schaffhausen BS. Characterization of an immortalizing N-terminal domain of polyomavirus large T antigen. J Virol. 1994 Feb; 68(2):668-73. PMID: 8289370.
    Citations: 18     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.