Harvard Catalyst Profiles

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David Jonathan Glass, M.D.

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Institution
Department
Address

Overview
Our lab is focused on the molecular mechanisms that control skeletal muscle homeostasis; signaling pathways regulating muscle atrophy and hypertrophy; mechanisms responsible for sarcopenia (age-related muscle atrophy and weakness)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Grunseich C, Miller R, Swan T, Glass DJ, El Mouelhi M, Fornaro M, Petricoul O, Vostiar I, Roubenoff R, Meriggioli MN, Kokkinis A, Guber RD, Budron MS, Vissing J, Soraru G, Mozaffar T, Ludolph A, Kissel JT, Fischbeck KH. Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial. Lancet Neurol. 2018 Dec; 17(12):1043-1052. PMID: 30337273.
    Citations:    Fields:    
  2. Mannick JB, Morris M, Hockey HP, Roma G, Beibel M, Kulmatycki K, Watkins M, Shavlakadze T, Zhou W, Quinn D, Glass DJ, Klickstein LB. TORC1 inhibition enhances immune function and reduces infections in the elderly. Sci Transl Med. 2018 Jul 11; 10(449). PMID: 29997249.
    Citations: 1     Fields:    
  3. Shavlakadze T, Zhu J, Wang S, Zhou W, Morin B, Egerman MA, Fan L, Wang Y, Iartchouk O, Meyer A, Valdez RA, Mannick JB, Klickstein LB, Glass DJ. Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology. J Gerontol A Biol Sci Med Sci. 2018 Jun 14; 73(7):845-852. PMID: 29304191.
    Citations: 1     Fields:    
  4. Cruz JM, Hupper N, Wilson LS, Concannon JB, Wang Y, Oberhauser B, Patora-Komisarska K, Zhang Y, Glass DJ, Trendelenburg AU, Clarke BA. Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy. J Biol Chem. 2018 07 27; 293(30):11837-11849. PMID: 29899111.
    Citations:    Fields:    
  5. Jones JE, Cadena SM, Gong C, Wang X, Chen Z, Wang SX, Vickers C, Chen H, Lach-Trifilieff E, Hadcock JR, Glass DJ. Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15. Cell Rep. 2018 Mar 20; 22(12):3375. PMID: 29562191.
    Citations:    Fields:    
  6. Jones JE, Cadena SM, Gong C, Wang X, Chen Z, Wang SX, Vickers C, Chen H, Lach-Trifilieff E, Hadcock JR, Glass DJ. Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15. Cell Rep. 2018 02 06; 22(6):1522-1530. PMID: 29425507.
    Citations: 1     Fields:    
  7. Das S, Morvan F, Morozzi G, Jourde B, Minetti GC, Kahle P, Rivet H, Brebbia P, Toussaint G, Glass DJ, Fornaro M. ATP Citrate Lyase Regulates Myofiber Differentiation and Increases Regeneration by Altering Histone Acetylation. Cell Rep. 2017 Dec 12; 21(11):3003-3011. PMID: 29241530.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Brzeszczynska J, Meyer A, McGregor R, Schilb A, Degen S, Tadini V, Johns N, Langen R, Schols A, Glass DJ, Roubenoff R, Ross JA, Fearon KCH, Greig CA, Jacobi C. Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia. J Cachexia Sarcopenia Muscle. 2018 02; 9(1):93-105. PMID: 29214748.
    Citations: 1     Fields:    Translation:Humans
  9. Glass DJ, Flier JS. Dealing with Consequences of Irreproducibility and Modifying the Published Literature: Retractions versus Revisions. Cell Metab. 2017 Nov 07; 26(5):695-696. PMID: 29117541.
    Citations:    Fields:    
  10. Morvan F, Rondeau JM, Zou C, Minetti G, Scheufler C, Scharenberg M, Jacobi C, Brebbia P, Ritter V, Toussaint G, Koelbing C, Leber X, Schilb A, Witte F, Lehmann S, Koch E, Geisse S, Glass DJ, Lach-Trifilieff E. Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12448-12453. PMID: 29109273.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Glass DJ. What's So Special about FGF19-Unique Effects Reported on Skeletal Muscle Mass and Function. Cell Metab. 2017 Aug 01; 26(2):287-288. PMID: 28768168.
    Citations:    Fields:    
  12. Summermatter S, Bouzan A, Pierrel E, Melly S, Stauffer D, Gutzwiller S, Nolin E, Dornelas C, Fryer C, Leighton-Davies J, Glass DJ, Fournier B. Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength. Mol Cell Biol. 2017 03 01; 37(5). PMID: 27956698.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  13. Skipworth RJ, Stephens NA, Johns N, Guttridge DC, Tisdale MJ, Baracos VE, Glass DJ. Ken Fearon. Cell Metab. 2016 12 13; 24(6):765-766. PMID: 28034417.
    Citations:    Fields:    Translation:Humans
  14. Brzeszczynska J, Johns N, Schilb A, Degen S, Degen M, Langen R, Schols A, Glass DJ, Roubenoff R, Greig CA, Jacobi C, Fearon KCh, Ross JA. Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly. Aging (Albany NY). 2016 08; 8(8):1690-702. PMID: 27454226.
    Citations: 3     Fields:    Translation:HumansCells
  15. Glass DJ. Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans. Cell Metab. 2016 07 12; 24(1):7-8. PMID: 27411004.
    Citations: 3     Fields:    Translation:Humans
  16. Gingras J, Gawor M, Bernadzki KM, Grady RM, Hallock P, Glass DJ, Sanes JR, Proszynski TJ. ?-Dystrobrevin-1 recruits Grb2 and a-catulin to organize neurotransmitter receptors at the neuromuscular junction. J Cell Sci. 2016 Mar 01; 129(5):898-911. PMID: 26769899; PMCID: PMC4813319.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  17. Hallock PT, Chin S, Blais S, Neubert TA, Glass DJ. Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation. Mol Cell Biol. 2016 01 15; 36(2):262-70. PMID: 26527617.
    Citations: 3     Fields:    Translation:AnimalsCells
  18. Lodka D, Pahuja A, Geers-Knörr C, Scheibe RJ, Nowak M, Hamati J, Köhncke C, Purfürst B, Kanashova T, Schmidt S, Glass DJ, Morano I, Heuser A, Kraft T, Bassel-Duby R, Olson EN, Dittmar G, Sommer T, Fielitz J. Muscle RING-finger 2 and 3 maintain striated-muscle structure and function. J Cachexia Sarcopenia Muscle. 2016 05; 7(2):165-80. PMID: 27493870.
    Citations: 4     Fields:    
  19. Gong C, Li Z, Ramanujan K, Clay I, Zhang Y, Lemire-Brachat S, Glass DJ. A long non-coding RNA, LncMyoD, regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation. Dev Cell. 2015 Jul 27; 34(2):181-91. PMID: 26143994.
    Citations: 37     Fields:    Translation:AnimalsCells
  20. Rodríguez JE, Liao JY, He J, Schisler JC, Newgard CB, Drujan D, Glass DJ, Frederick CB, Yoder BC, Lalush DS, Patterson C, Willis MS. The ubiquitin ligase MuRF1 regulates PPARa activity in the heart by enhancing nuclear export via monoubiquitination. Mol Cell Endocrinol. 2015 Sep 15; 413:36-48. PMID: 26116825; PMCID: PMC4523404.
    Citations: 11     Fields:    Translation:AnimalsCells
  21. Kneissel M, Glass D. Introduction special issue. Bone. 2015 Nov; 80:1. PMID: 26115912.
    Citations:    Fields:    Translation:HumansAnimals
  22. Das S, Morvan F, Jourde B, Meier V, Kahle P, Brebbia P, Toussaint G, Glass DJ, Fornaro M. ATP citrate lyase improves mitochondrial function in skeletal muscle. Cell Metab. 2015 Jun 02; 21(6):868-76. PMID: 26039450.
    Citations: 13     Fields:    Translation:HumansCells
  23. Egerman MA, Cadena SM, Gilbert JA, Meyer A, Nelson HN, Swalley SE, Mallozzi C, Jacobi C, Jennings LL, Clay I, Laurent G, Ma S, Brachat S, Lach-Trifilieff E, Shavlakadze T, Trendelenburg AU, Brack AS, Glass DJ. GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration. Cell Metab. 2015 Jul 07; 22(1):164-74. PMID: 26001423; PMCID: PMC4497834.
    Citations: 97     Fields:    Translation:HumansAnimalsCells
  24. Mannick JB, Del Giudice G, Lattanzi M, Valiante NM, Praestgaard J, Huang B, Lonetto MA, Maecker HT, Kovarik J, Carson S, Glass DJ, Klickstein LB. mTOR inhibition improves immune function in the elderly. Sci Transl Med. 2014 Dec 24; 6(268):268ra179. PMID: 25540326.
    Citations: 95     Fields:    Translation:HumansCellsPHPublic Health
  25. Amato AA, Sivakumar K, Goyal N, David WS, Salajegheh M, Praestgaard J, Lach-Trifilieff E, Trendelenburg AU, Laurent D, Glass DJ, Roubenoff R, Tseng BS, Greenberg SA. Treatment of sporadic inclusion body myositis with bimagrumab. Neurology. 2014 Dec 09; 83(24):2239-46. PMID: 25381300; PMCID: PMC4277670.
    Citations: 33     Fields:    Translation:HumansCells
  26. White JP, Wrann CD, Rao RR, Nair SK, Jedrychowski MP, You JS, Martínez-Redondo V, Gygi SP, Ruas JL, Hornberger TA, Wu Z, Glass DJ, Piao X, Spiegelman BM. G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy. Proc Natl Acad Sci U S A. 2014 Nov 04; 111(44):15756-61. PMID: 25336758; PMCID: PMC4226111.
    Citations: 15     Fields:    Translation:AnimalsCells
  27. Glass DJ. NIH grants: Focus on questions, not hypotheses. Nature. 2014 Mar 20; 507(7492):306. PMID: 24646984.
    Citations: 1     Fields:    Translation:HumansAnimals
  28. Baskin KK, Rodriguez MR, Kansara S, Chen W, Carranza S, Frazier OH, Glass DJ, Taegtmeyer H. MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart. J Mol Cell Cardiol. 2014 Jul; 72:168-76. PMID: 24650875; PMCID: PMC4037330.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  29. Iyer CC, McGovern VL, Wise DO, Glass DJ, Burghes AH. Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy. Neuromuscul Disord. 2014 May; 24(5):436-44. PMID: 24656734; PMCID: PMC4005840.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Glass DJ, Campbell KP, Rudnicki MA. Skeletal muscle's 3rd year anniversary. Skelet Muscle. 2014 Jan 24; 4(1):3. PMID: 24456943; PMCID: PMC3911964.
    Citations:    Fields:    
  31. Johns N, Hatakeyama S, Stephens NA, Degen M, Degen S, Frieauff W, Lambert C, Ross JA, Roubenoff R, Glass DJ, Jacobi C, Fearon KC. Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle. PLoS One. 2014; 9(1):e83618. PMID: 24404136; PMCID: PMC3880262.
    Citations: 10     Fields:    Translation:HumansCells
  32. Lach-Trifilieff E, Minetti GC, Sheppard K, Ibebunjo C, Feige JN, Hartmann S, Brachat S, Rivet H, Koelbing C, Morvan F, Hatakeyama S, Glass DJ. An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy. Mol Cell Biol. 2014 Feb; 34(4):606-18. PMID: 24298022; PMCID: PMC3911487.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  33. Minetti GC, Feige JN, Bombard F, Heier A, Morvan F, Nürnberg B, Leiss V, Birnbaumer L, Glass DJ, Fornaro M. Gai2 signaling is required for skeletal muscle growth, regeneration, and satellite cell proliferation and differentiation. Mol Cell Biol. 2014 Feb; 34(4):619-30. PMID: 24298018; PMCID: PMC3911486.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  34. Fornaro M, Hinken AC, Needle S, Hu E, Trendelenburg AU, Mayer A, Rosenstiel A, Chang C, Meier V, Billin AN, Becherer JD, Brace AD, Evans WJ, Glass DJ, Russell AJ. Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells. Am J Physiol Endocrinol Metab. 2014 Jan 15; 306(2):E150-6. PMID: 24253050.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  35. Egerman MA, Glass DJ. Signaling pathways controlling skeletal muscle mass. Crit Rev Biochem Mol Biol. 2014 Jan-Feb; 49(1):59-68. PMID: 24237131; PMCID: PMC3913083.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  36. Levy JR, Campbell KP, Glass DJ. MG53's new identity. Skelet Muscle. 2013 Nov 01; 3(1):25. PMID: 24175977; PMCID: PMC4177543.
    Citations: 1     Fields:    
  37. Li Z, Zhang Y, Ramanujan K, Ma Y, Kirsch DG, Glass DJ. Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway. Cancer Res. 2013 May 15; 73(10):3041-50. PMID: 23536553; PMCID: PMC3732831.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  38. Willis MS, Wadosky KM, Rodríguez JE, Schisler JC, Lockyer P, Hilliard EG, Glass DJ, Patterson C. Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo. Cell Biochem Funct. 2014 Jan; 32(1):39-50. PMID: 23512667; PMCID: PMC3728166.
    Citations: 14     Fields:    Translation:AnimalsCells
  39. Li Z, Gilbert JA, Zhang Y, Zhang M, Qiu Q, Ramanujan K, Shavlakadze T, Eash JK, Scaramozza A, Goddeeris MM, Kirsch DG, Campbell KP, Brack AS, Glass DJ. An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis. Dev Cell. 2012 Dec 11; 23(6):1176-88. PMID: 23177649; PMCID: PMC3645921.
    Citations: 35     Fields:    Translation:AnimalsCells
  40. Ibebunjo C, Chick JM, Kendall T, Eash JK, Li C, Zhang Y, Vickers C, Wu Z, Clarke BA, Shi J, Cruz J, Fournier B, Brachat S, Gutzwiller S, Ma Q, Markovits J, Broome M, Steinkrauss M, Skuba E, Galarneau JR, Gygi SP, Glass DJ. Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia. Mol Cell Biol. 2013 Jan; 33(2):194-212. PMID: 23109432; PMCID: PMC3554128.
    Citations: 56     Fields:    Translation:AnimalsCells
  41. Zaglia T, Milan G, Franzoso M, Bertaggia E, Pianca N, Piasentini E, Voltarelli VA, Chiavegato D, Brum PC, Glass DJ, Schiaffino S, Sandri M, Mongillo M. Cardiac sympathetic neurons provide trophic signal to the heart via ß2-adrenoceptor-dependent regulation of proteolysis. Cardiovasc Res. 2013 Feb 01; 97(2):240-50. PMID: 23090606.
    Citations: 14     Fields:    Translation:AnimalsCells
  42. Fearon KC, Glass DJ, Guttridge DC. Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metab. 2012 Aug 08; 16(2):153-66. PMID: 22795476.
    Citations: 191     Fields:    Translation:HumansCells
  43. Glass DJ, Spiegelman BM. Se-Jin Lee, myostatin discoverer, elected to the National Academy of Science. Skelet Muscle. 2012 Jun 07; 2(1):11. PMID: 22676848; PMCID: PMC3514131.
    Citations:    Fields:    
  44. Fournier B, Murray B, Gutzwiller S, Marcaletti S, Marcellin D, Bergling S, Brachat S, Persohn E, Pierrel E, Bombard F, Hatakeyama S, Trendelenburg AU, Morvan F, Richardson B, Glass DJ, Lach-Trifilieff E, Feige JN. Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism. Mol Cell Biol. 2012 Jul; 32(14):2871-9. PMID: 22586266; PMCID: PMC3416189.
    Citations: 29     Fields:    Translation:AnimalsCells
  45. Hu SI, Katz M, Chin S, Qi X, Cruz J, Ibebunjo C, Zhao S, Chen A, Glass DJ. MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle. Sci Signal. 2012 Feb 14; 5(211):ra14. PMID: 22337810.
    Citations: 13     Fields:    Translation:AnimalsCells
  46. Trendelenburg AU, Meyer A, Jacobi C, Feige JN, Glass DJ. TAK-1/p38/nNF?B signaling inhibits myoblast differentiation by increasing levels of Activin A. Skelet Muscle. 2012 Feb 07; 2(1):3. PMID: 22313861; PMCID: PMC3295657.
    Citations: 38     Fields:    
  47. Glass D, Campbell K, Rudnicki M. Skeletal Muscle - one year on. Skelet Muscle. 2012 Jan 05; 2(1):1. PMID: 22221535; PMCID: PMC3285074.
    Citations: 1     Fields:    
  48. Glass DJ, Arnold SE. Some evolutionary perspectives on Alzheimer's disease pathogenesis and pathology. Alzheimers Dement. 2012 Jul; 8(4):343-51. PMID: 22137143; PMCID: PMC3646265.
    Citations: 8     Fields:    Translation:Humans
  49. Minetti GC, Feige JN, Rosenstiel A, Bombard F, Meier V, Werner A, Bassilana F, Sailer AW, Kahle P, Lambert C, Glass DJ, Fornaro M. Gai2 signaling promotes skeletal muscle hypertrophy, myoblast differentiation, and muscle regeneration. Sci Signal. 2011 Nov 29; 4(201):ra80. PMID: 22126963.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  50. Shi J, Luo L, Eash J, Ibebunjo C, Glass DJ. The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling. Dev Cell. 2011 Nov 15; 21(5):835-47. PMID: 22033112.
    Citations: 40     Fields:    Translation:AnimalsCells
  51. Bleris L, Xie Z, Glass D, Adadey A, Sontag E, Benenson Y. Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template. Mol Syst Biol. 2011 Aug 02; 7:519. PMID: 21811230; PMCID: PMC3202791.
    Citations: 45     Fields:    Translation:HumansCells
  52. Usui S, Maejima Y, Pain J, Hong C, Cho J, Park JY, Zablocki D, Tian B, Glass DJ, Sadoshima J. Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB. Circ Res. 2011 Jul 08; 109(2):161-71. PMID: 21617130; PMCID: PMC3257317.
    Citations: 27     Fields:    Translation:AnimalsCells
  53. Rakhilin S, Turner G, Katz M, Warden R, Irelan J, Abassi YA, Glass DJ. Electrical impedance as a novel biomarker of myotube atrophy and hypertrophy. J Biomol Screen. 2011 Jul; 16(6):565-74. PMID: 21493966.
    Citations: 11     Fields:    Translation:AnimalsCells
  54. Lee SJ, Glass DJ. Treating cancer cachexia to treat cancer. Skelet Muscle. 2011 Jan 24; 1(1):2. PMID: 21798080; PMCID: PMC3143902.
    Citations: 19     Fields:    
  55. Glass DJ, Campbell KP, Rudnicki MA. Welcome to skeletal muscle. Skelet Muscle. 2011 Jan 24; 1(1):1. PMID: 21798079; PMCID: PMC3143905.
    Citations: 3     Fields:    
  56. Rüegg MA, Glass DJ. Molecular mechanisms and treatment options for muscle wasting diseases. Annu Rev Pharmacol Toxicol. 2011; 51:373-95. PMID: 20936944.
    Citations: 39     Fields:    Translation:HumansAnimals
  57. Ibebunjo C, Eash JK, Li C, Ma Q, Glass DJ. Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement. Am J Physiol Endocrinol Metab. 2011 Feb; 300(2):E327-40. PMID: 21045173.
    Citations: 28     Fields:    Translation:AnimalsCells
  58. Glass D, Roubenoff R. Recent advances in the biology and therapy of muscle wasting. Ann N Y Acad Sci. 2010 Nov; 1211:25-36. PMID: 21062293.
    Citations: 42     Fields:    Translation:HumansAnimals
  59. Glass DJ. A critique of the hypothesis, and a defense of the question, as a framework for experimentation. Clin Chem. 2010 Jul; 56(7):1080-5. PMID: 20511448.
    Citations: 3     Fields:    
  60. Glass DJ. Signaling pathways perturbing muscle mass. Curr Opin Clin Nutr Metab Care. 2010 May; 13(3):225-9. PMID: 20397318.
    Citations: 99     Fields:    Translation:Cells
  61. Mittal A, Bhatnagar S, Kumar A, Lach-Trifilieff E, Wauters S, Li H, Makonchuk DY, Glass DJ, Kumar A. The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice. J Cell Biol. 2010 Mar 22; 188(6):833-49. PMID: 20308426; PMCID: PMC2845082.
    Citations: 68     Fields:    Translation:Animals
  62. Glass DJ. PI3 kinase regulation of skeletal muscle hypertrophy and atrophy. Curr Top Microbiol Immunol. 2010; 346:267-78. PMID: 20593312.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  63. Cohen S, Brault JJ, Gygi SP, Glass DJ, Valenzuela DM, Gartner C, Latres E, Goldberg AL. During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol. 2009 Jun 15; 185(6):1083-95. PMID: 19506036; PMCID: PMC2711608.
    Citations: 178     Fields:    Translation:AnimalsCells
  64. Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ. Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. Am J Physiol Cell Physiol. 2009 Jun; 296(6):C1258-70. PMID: 19357233.
    Citations: 187     Fields:    Translation:HumansAnimalsCells
  65. Willis MS, Rojas M, Li L, Selzman CH, Tang RH, Stansfield WE, Rodriguez JE, Glass DJ, Patterson C. Muscle ring finger 1 mediates cardiac atrophy in vivo. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H997-H1006. PMID: 19168726; PMCID: PMC2670686.
    Citations: 45     Fields:    Translation:AnimalsCells
  66. Carrasco R, Lovell DJ, Giannini EH, Henderson CJ, Huang B, Kramer S, Ranz J, Heubi J, Glass D. Biochemical markers of bone turnover associated with calcium supplementation in children with juvenile rheumatoid arthritis: results of a double-blind, placebo-controlled intervention trial. Arthritis Rheum. 2008 Dec; 58(12):3932-40. PMID: 19035501; PMCID: PMC2630222.
    Citations: 4     Fields:    Translation:Humans
  67. Glass DJ, Hall N. A brief history of the hypothesis. Cell. 2008 Aug 08; 134(3):378-81. PMID: 18692458.
    Citations: 9     Fields:    
  68. Clarke BA, Drujan D, Willis MS, Murphy LO, Corpina RA, Burova E, Rakhilin SV, Stitt TN, Patterson C, Latres E, Glass DJ. The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell Metab. 2007 Nov; 6(5):376-85. PMID: 17983583.
    Citations: 173     Fields:    Translation:AnimalsCells
  69. Li HH, Willis MS, Lockyer P, Miller N, McDonough H, Glass DJ, Patterson C. Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. J Clin Invest. 2007 Nov; 117(11):3211-23. PMID: 17965779; PMCID: PMC2040316.
    Citations: 97     Fields:    Translation:HumansAnimalsCells
  70. Fielitz J, Kim MS, Shelton JM, Latif S, Spencer JA, Glass DJ, Richardson JA, Bassel-Duby R, Olson EN. Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3. J Clin Invest. 2007 Sep; 117(9):2486-95. PMID: 17786241; PMCID: PMC1957544.
    Citations: 86     Fields:    Translation:AnimalsCells
  71. Glass DJ. Two tales concerning skeletal muscle. J Clin Invest. 2007 Sep; 117(9):2388-91. PMID: 17786235; PMCID: PMC1952649.
    Citations: 7     Fields:    Translation:AnimalsCells
  72. Okamoto H, Latres E, Liu R, Thabet K, Murphy A, Valenzeula D, Yancopoulos GD, Stitt TN, Glass DJ, Sleeman MW. Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis. Diabetes. 2007 May; 56(5):1350-6. PMID: 17303803.
    Citations: 33     Fields:    Translation:AnimalsCells
  73. Willis MS, Ike C, Li L, Wang DZ, Glass DJ, Patterson C. Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circ Res. 2007 Mar 02; 100(4):456-9. PMID: 17272810; PMCID: PMC4112093.
    Citations: 87     Fields:    Translation:Animals
  74. Crepaldi T, Bersani F, Scuoppo C, Accornero P, Prunotto C, Taulli R, Forni PE, Leo C, Chiarle R, Griffiths J, Glass DJ, Ponzetto C. Conditional activation of MET in differentiated skeletal muscle induces atrophy. J Biol Chem. 2007 Mar 02; 282(9):6812-22. PMID: 17194700.
    Citations: 12     Fields:    Translation:AnimalsCells
  75. Mor-Vaknin N, Punturieri A, Sitwala K, Faulkner N, Legendre M, Khodadoust MS, Kappes F, Ruth JH, Koch A, Glass D, Petruzzelli L, Adams BS, Markovitz DM. The DEK nuclear autoantigen is a secreted chemotactic factor. Mol Cell Biol. 2006 Dec; 26(24):9484-96. PMID: 17030615; PMCID: PMC1698538.
    Citations: 34     Fields:    Translation:HumansCells
  76. Glass DJ. A signaling role for dystrophin: inhibiting skeletal muscle atrophy pathways. Cancer Cell. 2005 Nov; 8(5):351-2. PMID: 16286242.
    Citations: 11     Fields:    Translation:AnimalsCells
  77. Glass DJ. Skeletal muscle hypertrophy and atrophy signaling pathways. Int J Biochem Cell Biol. 2005 Oct; 37(10):1974-84. PMID: 16087388.
    Citations: 258     Fields:    Translation:HumansCells
  78. Sleeman MW, Wortley KE, Lai KM, Gowen LC, Kintner J, Kline WO, Garcia K, Stitt TN, Yancopoulos GD, Wiegand SJ, Glass DJ. Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity. Nat Med. 2005 Feb; 11(2):199-205. PMID: 15654325.
    Citations: 64     Fields:    Translation:AnimalsCells
  79. Latres E, Amini AR, Amini AA, Griffiths J, Martin FJ, Wei Y, Lin HC, Yancopoulos GD, Glass DJ. Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. J Biol Chem. 2005 Jan 28; 280(4):2737-44. PMID: 15550386.
    Citations: 134     Fields:    Translation:AnimalsCells
  80. Lai KM, Gonzalez M, Poueymirou WT, Kline WO, Na E, Zlotchenko E, Stitt TN, Economides AN, Yancopoulos GD, Glass DJ. Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy. Mol Cell Biol. 2004 Nov; 24(21):9295-304. PMID: 15485899; PMCID: PMC522257.
    Citations: 122     Fields:    Translation:AnimalsCells
  81. Cai D, Frantz JD, Tawa NE, Melendez PA, Oh BC, Lidov HG, Hasselgren PO, Frontera WR, Lee J, Glass DJ, Shoelson SE. IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell. 2004 Oct 15; 119(2):285-98. PMID: 15479644.
    Citations: 371     Fields:    Translation:HumansAnimalsCells
  82. Veitenhansl M, Stegner K, Hierl FX, Dieterle C, Feldmeier H, Gutt B, Landgraf R, Garrow AP, Vileikyte L, Findlow A, Waterman C, Boulton AJ, Shankhdhar K, Shankhdhar L, Shankhdhar U, Petrova NL, Foster AV, Edmonds ME, Ferraresi R, Caravaggi C, De Giglio R, Cavaiani P, Pogliaghi I, Sommariva E, Katz IA, Harlan A, Miranda-Palma B, Prieto-Sanchez L, Armstrong DG, Bowker JH, Mizel MS, Cernea S, Wohlgelernter J, Kidron M, Modi P, Raz I, Arbit E, Nosek L, Kapitza C, Beckett P, Gelfand R, Goldberg M, Heise T, Testa MA, Turner RR, Hayes JF, Scranton RE, Simonson DC, Yang YW, Hsu YJ, Naujok O, Francini F, Jörns A, Tiedge M, Lenzen S, Abdel-Wahab YH, Marenah L, Orr DF, Shaw C, Flatt PR, Chokkalingam K, Mansell PI, Clausen P, Ekbom P, Damm P, Feldt-Rasmussen U, Nielsen B, Mathiesen ER, Feldt-Rasmussen B, Dewan S, Da Silva N, Ternan PM, Leong KS, Wilding JP, Asatiani N, Kurashvili R, Dundua M, Shelestova E, Pagava K, Ramazashvili M, Hod M, Smirnov S, Petersen JL, Justesen TI, Ringholm Nielsen L, Müller C, Højlund K, Wensaas A, Kase ET, Aas V, Rustan AC, Thoresen GH, Levin K, Beck-Nielsen H, Gaster M, Im SS, Kang SY, Kim SY, Ahn YH, Lihn AS, Schmoll D, Werner T, Kienitz A, Meyer M, Barthel A, Ailett F, Sutherland C, Walther R, Grempler R, Sasson S, Reich R, Tenenbaum T, Alpert E, Anfossi G, Russo I, Traversa M, Massucco P, Mattiello L, Doronzo G, Trovati M, Lally S, Tan CY, Owens D, Tomkin GH, Porchay I, Péan F, Bellili N, Betoulle D, Balkau B, Tichet J, Marre M, Fumeron F, Chatellier G, Alhenc-Gelas F, Nichols GA, Brown JB, Hayes RP, Bowman L, Drexel H, Saely CH, Marte T, Benzer W, Langer P, Hoefle G, Moll W, Aczel S, Karagiannis E, Lübben G, Urquhart R, Edwards G, Bruce S, Howlett HS, Cugnardey N, Turner KC, Park JS, Fiedorek FT, Avogaro A, Gallo A, Pinton P, Rizzuto R, Murphy E, Ceolotto G, Caterson I, Guy-Grand B, Hill J, Barone M, Aiello A, Allochis G, Borzì V, Cannatà F, Caronna S, D'Avanzo A, Elli R, Formoso G, Paroli A, Scardapane R, Sorichetti P, Tatti P, Viviani G, Santeusanio F, Manzella D, Grella R, Abbatecola AM, Paolisso G, Søndergaard LG, Monster TB, Johnsen SP, Olsen ML, McLaughlin JK, Sørensen HT, Lervang HH, Rungby J, Lyssenko V, Fredriksson J, Almgren P, Anevski D, Orho-Melander M, Sjögren M, Tuomi T, Groop L, Jaziri R, Aubert R, Tuomilehto J, Hu G, Jousilahti P, Peltonen M, Lindstrom J, Laina A, Alevizaki M, Philippou G, Souvatzoglou A, Anastasiou E, Alba S, Metcalf BS, Voss LD, Jeffery AN, Wilkin TJ, Glüimer C, Colagiuri S, Vistisen D, Borch-Johnsen K, Haynes A, Bower C, Bulsara MK, Jones TW, Davis EA, Mortensen HB, Hougaard P, Holl R, Swift P, Pociot F, Knip M, Hansen L, Szadkowska A, Pietrzak I, Zmyslowska A, Wyka K, Bodalski J, Holl RW, Swift R, Hougaard R, Gerstl EM, Engelsberger I, Rabl W, Rosenbauer J, Gröbe H, Hofer SE, Krause U, Dabelea D, Morgan T, Pettitt DJ, Dolan L, Mayer-Davis EJ, Pihoker C, Hillier TA, Imperatore G, Ruggiero A, Hamman RE, Stylianou A, Tentolouris N, Perrea D, Tselepis AD, Lourida E, Kitsou E, Katsilambros N, Vedovato M, Dodesini AR, Lepore G, Tiengo A, Trevisan R, Penno G, Miccoli R, Pucci L, Lucchesi D, Bandinelli S, Fotino C, Triscornia S, Baldassari E, Del Prato S, Reboldi P, Santeusanio E, Fuller J, Langham RG, Gow RM, Zhang Y, Kelly DJ, Christensen PK, Parving HH, Gilbert RE, Chibalin AV, Zhong Z, Kotova O, Davidescu A, Ehrén I, Ekberg K, Wahren J, Wassef L, Buckley AJ, Rooney KB, Briody J, Thompson M, Ozanne SE, Thompson CH, Chamson-Reig A, Summers K, Arany EJ, Hill DJ, Solerte SB, Gazzaruso C, Locatelli E, Precerutti S, Schifino N, Ferrari E, Fioravanti M, Phenekos CV, Ginis A, Fragaki I, Chalkiadaki M, Tzioras C, Powell LA, McGuire GM, Jewhurst V, Trimble ER, Rasmussen BM, Vessby B, Uusitupa M, Berglund L, Pedersen E, Riccardi G, Rivellese AA, Tapsell L, Hermansen K, da Silva Xavier G, Rutter J, Rutter GA, Briaud IM, Lingohr MK, Dickson LM, McCuaig JR, Lawrence JC, Rhodes CJ, Wikstrom JD, Katzman SM, Shirihai OS, Yang J, Deng S, Wang X, Hessner MJ, Wu J, Wong RK, et al. 40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 2004 Aug; 47(Suppl 1):A1-A464. PMID: 27770180.
    Citations: 2     Fields:    
  83. Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, Gonzalez M, Yancopoulos GD, Glass DJ. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell. 2004 May 07; 14(3):395-403. PMID: 15125842.
    Citations: 477     Fields:    Translation:AnimalsCells
  84. Glass DJ, Harper AS. Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine. BMC Fam Pract. 2003 Aug 13; 4:10. PMID: 12917016; PMCID: PMC194638.
    Citations: 3     Fields:    Translation:Humans
  85. Glass DJ. Molecular mechanisms modulating muscle mass. Trends Mol Med. 2003 Aug; 9(8):344-50. PMID: 12928036.
    Citations: 86     Fields:    Translation:HumansCells
  86. Glass DJ. Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat Cell Biol. 2003 Feb; 5(2):87-90. PMID: 12563267.
    Citations: 168     Fields:    Translation:HumansAnimalsCells
  87. Burgess RW, Dickman DK, Nunez L, Glass DJ, Sanes JR. Mapping sites responsible for interactions of agrin with neurons. J Neurochem. 2002 Oct; 83(2):271-84. PMID: 12423238.
    Citations: 17     Fields:    Translation:AnimalsCells
  88. Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ, Yancopoulos GD. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol. 2001 Nov; 3(11):1014-9. PMID: 11715023.
    Citations: 614     Fields:    Translation:AnimalsCells
  89. Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD, Glass DJ. Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol. 2001 Nov; 3(11):1009-13. PMID: 11715022.
    Citations: 407     Fields:    Translation:AnimalsCells
  90. Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science. 2001 Nov 23; 294(5547):1704-8. PMID: 11679633.
    Citations: 847     Fields:    Translation:HumansAnimalsCells
  91. Berzin TM, Zipser BD, Rafii MS, Kuo-Leblanc V, Yancopoulos GD, Glass DJ, Fallon JR, Stopa EG. Agrin and microvascular damage in Alzheimer's disease. Neurobiol Aging. 2000 Mar-Apr; 21(2):349-55. PMID: 10867220.
    Citations: 31     Fields:    Translation:Humans
  92. Rommel C, Clarke BA, Zimmermann S, Nuñez L, Rossman R, Reid K, Moelling K, Yancopoulos GD, Glass DJ. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science. 1999 Nov 26; 286(5445):1738-41. PMID: 10576741.
    Citations: 193     Fields:    Translation:AnimalsCells
  93. Zhou H, Glass DJ, Yancopoulos GD, Sanes JR. Distinct domains of MuSK mediate its abilities to induce and to associate with postsynaptic specializations. J Cell Biol. 1999 Sep 06; 146(5):1133-46. PMID: 10477765; PMCID: PMC2169478.
    Citations: 47     Fields:    Translation:AnimalsCells
  94. Donahue JE, Berzin TM, Rafii MS, Glass DJ, Yancopoulos GD, Fallon JR, Stopa EG. Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchyma. Proc Natl Acad Sci U S A. 1999 May 25; 96(11):6468-72. PMID: 10339611; PMCID: PMC26905.
    Citations: 13     Fields:    Translation:HumansCells
  95. Gautam M, DeChiara TM, Glass DJ, Yancopoulos GD, Sanes JR. Distinct phenotypes of mutant mice lacking agrin, MuSK, or rapsyn. Brain Res Dev Brain Res. 1999 May 14; 114(2):171-8. PMID: 10320756.
    Citations: 18     Fields:    Translation:AnimalsCells
  96. Glass D, Boorman GC, Stables GI, Cunliffe WJ, Goode K. A placebo-controlled clinical trial to compare a gel containing a combination of isotretinoin (0.05%) and erythromycin (2%) with gels containing isotretinoin (0.05%) or erythromycin (2%) alone in the topical treatment of acne vulgaris. Dermatology. 1999; 199(3):242-7. PMID: 10592405.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  97. Bowen DC, Park JS, Bodine S, Stark JL, Valenzuela DM, Stitt TN, Yancopoulos GD, Lindsay RM, Glass DJ, DiStefano PS. Localization and regulation of MuSK at the neuromuscular junction. Dev Biol. 1998 Jul 15; 199(2):309-19. PMID: 9698449.
    Citations: 19     Fields:    Translation:AnimalsCells
  98. Sanes JR, Apel ED, Burgess RW, Emerson RB, Feng G, Gautam M, Glass D, Grady RM, Krejci E, Lichtman JW, Lu JT, Massoulié J, Miner JH, Moscoso LM, Nguyen Q, Nichol M, Noakes PG, Patton BL, Son YJ, Yancopoulos GD, Zhou H. Development of the neuromuscular junction: genetic analysis in mice. J Physiol Paris. 1998 Jun-Aug; 92(3-4):167-72. PMID: 9789802.
    Citations: 9     Fields:    Translation:AnimalsCells
  99. Sanes JR, Apel ED, Gautam M, Glass D, Grady RM, Martin PT, Nichol MC, Yancopoulos GD. Agrin receptors at the skeletal neuromuscular junction. Ann N Y Acad Sci. 1998 May 13; 841:1-13. PMID: 9668217.
    Citations: 5     Fields:    Translation:AnimalsCells
  100. Shrivastava A, Radziejewski C, Campbell E, Kovac L, McGlynn M, Ryan TE, Davis S, Goldfarb MP, Glass DJ, Lemke G, Yancopoulos GD. An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. Mol Cell. 1997 Dec; 1(1):25-34. PMID: 9659900.
    Citations: 118     Fields:    Translation:AnimalsCells
  101. Sugiyama JE, Glass DJ, Yancopoulos GD, Hall ZW. Laminin-induced acetylcholine receptor clustering: an alternative pathway. J Cell Biol. 1997 Oct 06; 139(1):181-91. PMID: 9314538; PMCID: PMC2139811.
    Citations: 24     Fields:    Translation:AnimalsCells
  102. Glass DJ, Apel ED, Shah S, Bowen DC, DeChiara TM, Stitt TN, Sanes JR, Yancopoulos GD. Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: required role for the MuSK ectodomain? Proc Natl Acad Sci U S A. 1997 Aug 05; 94(16):8848-53. PMID: 9238066; PMCID: PMC23162.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  103. Glass DJ, Yancopoulos GD. Sequential roles of agrin, MuSK and rapsyn during neuromuscular junction formation. Curr Opin Neurobiol. 1997 Jun; 7(3):379-84. PMID: 9232805.
    Citations: 13     Fields:    Translation:AnimalsCells
  104. Apel ED, Glass DJ, Moscoso LM, Yancopoulos GD, Sanes JR. Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold. Neuron. 1997 Apr; 18(4):623-35. PMID: 9136771.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  105. Wong V, Glass DJ, Arriaga R, Yancopoulos GD, Lindsay RM, Conn G. Hepatocyte growth factor promotes motor neuron survival and synergizes with ciliary neurotrophic factor. J Biol Chem. 1997 Feb 21; 272(8):5187-91. PMID: 9030587.
    Citations: 13     Fields:    Translation:AnimalsCells
  106. Lai KO, Glass DJ, Geis D, Yancopoulos GD, Ip NY. Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras. J Neurosci Res. 1996 Dec 01; 46(5):618-29. PMID: 8951673.
    Citations:    Fields:    Translation:HumansAnimalsCells
  107. DeChiara TM, Bowen DC, Valenzuela DM, Simmons MV, Poueymirou WT, Thomas S, Kinetz E, Compton DL, Rojas E, Park JS, Smith C, DiStefano PS, Glass DJ, Burden SJ, Yancopoulos GD. The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo. Cell. 1996 May 17; 85(4):501-12. PMID: 8653786.
    Citations: 179     Fields:    Translation:AnimalsCells
  108. Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, Ryan TE, Gies DR, Shah S, Mattsson K, Burden SJ, DiStefano PS, Valenzuela DM, DeChiara TM, Yancopoulos GD. Agrin acts via a MuSK receptor complex. Cell. 1996 May 17; 85(4):513-23. PMID: 8653787.
    Citations: 148     Fields:    Translation:AnimalsCells
  109. Glass DJ, DeChiara TM, Stitt TN, DiStefano PS, Valenzuela DM, Yancopoulos GD. The receptor tyrosine kinase MuSK is required for neuromuscular junction formation and is a functional receptor for agrin. Cold Spring Harb Symp Quant Biol. 1996; 61:435-44. PMID: 9246472.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  110. Guiton M, Gunn-Moore FJ, Glass DJ, Geis DR, Yancopoulos GD, Tavaré JM. Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signaling. J Biol Chem. 1995 Sep 01; 270(35):20384-90. PMID: 7657612.
    Citations: 8     Fields:    Translation:AnimalsCells
  111. Rydén M, Murray-Rust J, Glass D, Ilag LL, Trupp M, Yancopoulos GD, McDonald NQ, Ibáñez CF. Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling. EMBO J. 1995 May 01; 14(9):1979-90. PMID: 7744005; PMCID: PMC398297.
    Citations: 21     Fields:    Translation:AnimalsCells
  112. Ilag LL, Curtis R, Glass D, Funakoshi H, Tobkes NJ, Ryan TE, Acheson A, Lindsay RM, Persson H, Yancopoulos GD, et al. Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo. Proc Natl Acad Sci U S A. 1995 Jan 17; 92(2):607-11. PMID: 7831338; PMCID: PMC42791.
    Citations: 1     Fields:    Translation:AnimalsCells
  113. Hantzopoulos PA, Suri C, Glass DJ, Goldfarb MP, Yancopoulos GD. The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins. Neuron. 1994 Jul; 13(1):187-201. PMID: 8043276.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  114. Altenberg GA, Young G, Horton JK, Glass D, Belli JA, Reuss L. Changes in intra- or extracellular pH do not mediate P-glycoprotein-dependent multidrug resistance. Proc Natl Acad Sci U S A. 1993 Oct 15; 90(20):9735-8. PMID: 8105483; PMCID: PMC47645.
    Citations: 12     Fields:    Translation:AnimalsCells
  115. Glass DJ, Yancopoulos GD. The neurotrophins and their receptors. Trends Cell Biol. 1993 Aug; 3(8):262-8. PMID: 14731744.
    Citations: 14     Fields:    
  116. Barker PA, Lomen-Hoerth C, Gensch EM, Meakin SO, Glass DJ, Shooter EM. Tissue-specific alternative splicing generates two isoforms of the trkA receptor. J Biol Chem. 1993 Jul 15; 268(20):15150-7. PMID: 8325889.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  117. Valenzuela DM, Maisonpierre PC, Glass DJ, Rojas E, Nuñez L, Kong Y, Gies DR, Stitt TN, Ip NY, Yancopoulos GD. Alternative forms of rat TrkC with different functional capabilities. Neuron. 1993 May; 10(5):963-74. PMID: 8494647.
    Citations: 58     Fields:    Translation:AnimalsCells
  118. Ip NY, Stitt TN, Tapley P, Klein R, Glass DJ, Fandl J, Greene LA, Barbacid M, Yancopoulos GD. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron. 1993 Feb; 10(2):137-49. PMID: 7679912.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  119. Nye SH, Squinto SP, Glass DJ, Stitt TN, Hantzopoulos P, Macchi MJ, Lindsay NS, Ip NY, Yancopoulos GD. K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses. Mol Biol Cell. 1992 Jun; 3(6):677-86. PMID: 1323351.
    Citations: 29     Fields:    Translation:AnimalsCells
  120. Glass DJ, Gies DR, Stitt T, Davis S, Hantzopoulos P, Ip NY, Goldfarb M, Yancopoulos GD. Cloning and analysis of neurotrophic factor receptors using function-based strategies. Cold Spring Harb Symp Quant Biol. 1992; 57:53-62. PMID: 1339690.
    Citations:    Fields:    Translation:HumansAnimalsCells
  121. Glass DJ, Nye SH, Hantzopoulos P, Macchi MJ, Squinto SP, Goldfarb M, Yancopoulos GD. TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor. Cell. 1991 Jul 26; 66(2):405-13. PMID: 1649703.
    Citations: 35     Fields:    Translation:AnimalsCells
  122. Squinto SP, Stitt TN, Aldrich TH, Davis S, Bianco SM, Radziejewski C, Glass DJ, Masiakowski P, Furth ME, Valenzuela DM, et al. trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell. 1991 May 31; 65(5):885-93. PMID: 1710174.
    Citations: 102     Fields:    Translation:AnimalsCells
  123. Glass DJ. Agricultural biotechnology: occupational health and regulatory issues. Occup Med. 1991 Apr-Jun; 6(2):301-10. PMID: 2047979.
    Citations:    Fields:    Translation:Humans
  124. Glass DJ, Owens ED. States noticing field releases. Biotechnology (N Y). 1990 Nov; 8(11):1064. PMID: 1366933.
    Citations:    Fields:    Translation:PHPublic Health
  125. Parker CM, Groh V, Band H, Porcelli SA, Morita C, Fabbi M, Glass D, Strominger JL, Brenner MB. Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire. J Exp Med. 1990 May 01; 171(5):1597-612. PMID: 2185330; PMCID: PMC2187908.
    Citations: 140     Fields:    Translation:HumansCells
  126. Glass DJ, Rees-Jones RW, Goff SP. Isolation and characterization of flat revertant cell lines from A-MuLV-transformed fibroblasts. Oncogene Res. 1990; 5(3):175-85. PMID: 2157187.
    Citations: 1     Fields:    Translation:AnimalsCells
  127. Glass DJ, Polvere RI, Van der Ploeg LH. Conserved sequences and transcription of the hsp70 gene family in Trypanosoma brucei. Mol Cell Biol. 1986 Dec; 6(12):4657-66. PMID: 3796613; PMCID: PMC367251.
    Citations: 40     Fields:    Translation:AnimalsCells
  128. Shea C, Glass DJ, Parangi S, Van der Ploeg LH. Variant surface glycoprotein gene expression site switches in Trypanosoma brucei. J Biol Chem. 1986 May 05; 261(13):6056-63. PMID: 3009443.
    Citations: 9     Fields:    Translation:AnimalsCells
  129. Brodman R, Gilfillan R, Glass D, Schur PH. Influenzal vaccine response in systemic lupus erythematosus. Ann Intern Med. 1978 Jun; 88(6):735-40. PMID: 307353.
    Citations: 18     Fields:    Translation:HumansPHPublic Health
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.