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Erik J Uhlmann, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Krichevsky AM, Uhlmann EJ. Oligonucleotide Therapeutics as a New Class of Drugs for Malignant Brain Tumors: Targeting mRNAs, Regulatory RNAs, Mutations, Combinations, and Beyond. Neurotherapeutics. 2019 Jan 14. PMID: 30644073.
    Citations:    Fields:    
  2. Carney BJ, Uhlmann EJ, Puligandla M, Mantia C, Weber GM, Neuberg DS, Zwicker JI. Intracranial hemorrhage with direct oral anticoagulants in patients with brain tumors. J Thromb Haemost. 2019 Jan; 17(1):72-76. PMID: 30450803.
    Citations:    Fields:    
  3. Mantia C, Uhlmann EJ, Puligandla M, Weber GM, Neuberg D, Zwicker JI. Predicting the higher rate of intracranial hemorrhage in glioma patients receiving therapeutic enoxaparin. Blood. 2017 06 22; 129(25):3379-3385. PMID: 28468796.
    Citations: 6     Fields:    Translation:Humans
  4. El Fatimy R, Subramanian S, Uhlmann EJ, Krichevsky AM. Genome Editing Reveals Glioblastoma Addiction to MicroRNA-10b. Mol Ther. 2017 02 01; 25(2):368-378. PMID: 28153089.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  5. Wong HA, Fatimy RE, Onodera C, Wei Z, Yi M, Mohan A, Gowrisankaran S, Karmali P, Marcusson E, Wakimoto H, Stephens R, Uhlmann EJ, Song JS, Tannous B, Krichevsky AM. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma. Mol Ther. 2015 Jul; 23(7):1234-1247. PMID: 28142001.
    Citations:    
  6. Weinstock MJ, Uhlmann EJ, Zwicker JI. Intracranial hemorrhage in cancer patients treated with anticoagulation. Thromb Res. 2016 Apr; 140 Suppl 1:S60-5. PMID: 27067980.
    Citations: 3     Fields:    Translation:Humans
  7. Teplyuk NM, Uhlmann EJ, Gabriely G, Volfovsky N, Wang Y, Teng J, Karmali P, Marcusson E, Peter M, Mohan A, Kraytsberg Y, Cialic R, Chiocca EA, Godlewski J, Tannous B, Krichevsky AM. Therapeutic potential of targeting microRNA-10b in established intracranial glioblastoma: first steps toward the clinic. EMBO Mol Med. 2016 Mar 01; 8(3):268-87. PMID: 26881967.
    Citations: 12     Fields:    Translation:HumansAnimals
  8. Mahadevan A, Sampson C, LaRosa S, Floyd SR, Wong ET, Uhlmann EJ, Sengupta S, Kasper EM. Dosimetric analysis of the alopecia preventing effect of hippocampus sparing whole brain radiation therapy. Radiat Oncol. 2015 Nov 26; 10:245. PMID: 26611656; PMCID: PMC4662000.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  9. Ippen FM, Mahadevan A, Wong ET, Uhlmann EJ, Sengupta S, Kasper EM. Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection. J Oncol. 2015; 2015:636918. PMID: 26681942; PMCID: PMC4668321.
    Citations: 4     
  10. Donato J, Campigotto F, Uhlmann EJ, Coletti E, Neuberg D, Weber GM, Zwicker JI. Intracranial hemorrhage in patients with brain metastases treated with therapeutic enoxaparin: a matched cohort study. Blood. 2015 Jul 23; 126(4):494-9. PMID: 25987658; PMCID: PMC4548746.
    Citations: 11     Fields:    Translation:Humans
  11. Wong HA, Fatimy RE, Onodera C, Wei Z, Yi M, Mohan A, Gowrisankaran S, Karmali P, Marcusson E, Wakimoto H, Stephens R, Uhlmann EJ, Song JS, Tannous B, Krichevsky AM. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma. Mol Ther. 2015 Jul; 23(7):1234-1247. PMID: 25903473; PMCID: PMC4817797.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  12. Teplyuk NM, Uhlmann EJ, Wong AH, Karmali P, Basu M, Gabriely G, Jain A, Wang Y, Chiocca EA, Stephens R, Marcusson E, Yi M, Krichevsky AM. MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma. Oncotarget. 2015 Feb 28; 6(6):3770-83. PMID: 25738367; PMCID: PMC4414152.
    Citations: 10     Fields:    Translation:HumansCells
  13. Rangachari D, Yamaguchi N, VanderLaan PA, Folch E, Mahadevan A, Floyd SR, Uhlmann EJ, Wong ET, Dahlberg SE, Huberman MS, Costa DB. Brain metastases in patients with EGFR-mutated or ALK-rearranged non-small-cell lung cancers. Lung Cancer. 2015 Apr; 88(1):108-11. PMID: 25682925.
    Citations: 50     Fields:    Translation:Humans
  14. Tzachanis D, Hamdan A, Uhlmann EJ, Joyce RM. Successful treatment of refractory Guillain-Barré syndrome with alemtuzumab in a patient with chronic lymphocytic leukemia. Acta Haematol. 2014; 132(2):240-3. PMID: 24853856.
    Citations: 2     Fields:    Translation:HumansCells
  15. Uhlmann EJ, Shenoy S, Goodnough LT. Successful treatment of recurrent hyperhemolysis syndrome with immunosuppression and plasma-to-red blood cell exchange transfusion. Transfusion. 2014 Feb; 54(2):384-8. PMID: 23692505.
    Citations:    Fields:    Translation:Humans
  16. Floyd SR, Kasper EM, Uhlmann EJ, Fonkem E, Wong ET, Mahadevan A. Hypofractionated Radiotherapy and Stereotactic Boost with Concurrent and Adjuvant Temozolamide for Glioblastoma in Good Performance Status Elderly Patients - Early Results of a Phase II Trial. Front Oncol. 2012; 2:122. PMID: 23087896; PMCID: PMC3472503.
    Citations: 9     
  17. Fonkem E, Uhlmann EJ, Floyd SR, Mahadevan A, Kasper E, Eton O, Wong ET. Melanoma brain metastasis: overview of current management and emerging targeted therapies. Expert Rev Neurother. 2012 Oct; 12(10):1207-15. PMID: 23082737.
    Citations: 25     Fields:    Translation:HumansCells
  18. Uhlmann EJ, Plotkin SR. Neurofibromatoses. Adv Exp Med Biol. 2012; 724:266-77. PMID: 22411249.
    Citations: 7     Fields:    Translation:Humans
  19. McKinney AM, Lohman BD, Sarikaya B, Uhlmann E, Spanbauer J, Singewald T, Brace JR. Acute hepatic encephalopathy: diffusion-weighted and fluid-attenuated inversion recovery findings, and correlation with plasma ammonia level and clinical outcome. AJNR Am J Neuroradiol. 2010 Sep; 31(8):1471-9. PMID: 20448015.
    Citations: 11     Fields:    Translation:Humans
  20. Uhlmann EJ, Dunitz JM, Fiol ME. Pulmonary vein thrombosis after lung transplantation presenting as stroke. J Heart Lung Transplant. 2009 Feb; 28(2):209-10. PMID: 19201351.
    Citations: 2     Fields:    Translation:Humans
  21. Uhlmann EJ, Seed PC, Schwan TG, Storch GA. Tick-borne relapsing fever polymerase chain reaction of tick-borne relapsing fever caused by Borrelia hermsii. Pediatr Infect Dis J. 2007 Mar; 26(3):267-9. PMID: 17484230.
    Citations: 3     Fields:    Translation:HumansCells
  22. Jansen LA, Uhlmann EJ, Crino PB, Gutmann DH, Wong M. Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes. Epilepsia. 2005 Dec; 46(12):1871-80. PMID: 16393152.
    Citations: 47     Fields:    Translation:AnimalsCells
  23. Uhlmann EJ, Tebas P, Storch GA, Powderly WG, Lie YS, Whitcomb JM, Hellmann NS, Arens MQ. Effects of the G190A substitution of HIV reverse transcriptase on phenotypic susceptibility of patient isolates to delavirdine. J Clin Virol. 2004 Nov; 31(3):198-203. PMID: 15465412.
    Citations: 4     Fields:    Translation:Humans
  24. Fraser MM, Zhu X, Kwon CH, Uhlmann EJ, Gutmann DH, Baker SJ. Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo. Cancer Res. 2004 Nov 01; 64(21):7773-9. PMID: 15520182.
    Citations: 86     Fields:    Translation:AnimalsCells
  25. Uhlmann EJ, Li W, Scheidenhelm DK, Gau CL, Tamanoi F, Gutmann DH. Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation. Glia. 2004 Aug 01; 47(2):180-8. PMID: 15185396.
    Citations: 30     Fields:    Translation:AnimalsCells
  26. Uhlmann EJ, Eby CS. Recombinant activated factor VII for non-hemophiliac bleeding patients. Curr Opin Hematol. 2004 May; 11(3):198-204. PMID: 15257021.
    Citations: 6     Fields:    Translation:HumansAnimals
  27. Ess KC, Uhlmann EJ, Li W, Li H, Declue JE, Crino PB, Gutmann DH. Expression profiling in tuberous sclerosis complex (TSC) knockout mouse astrocytes to characterize human TSC brain pathology. Glia. 2004 Apr 01; 46(1):28-40. PMID: 14999811.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  28. Wong M, Ess KC, Uhlmann EJ, Jansen LA, Li W, Crino PB, Mennerick S, Yamada KA, Gutmann DH. Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Ann Neurol. 2003 Aug; 54(2):251-6. PMID: 12891680.
    Citations: 63     Fields:    Translation:AnimalsCells
  29. Tabancay AP, Gau CL, Machado IM, Uhlmann EJ, Gutmann DH, Guo L, Tamanoi F. Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K. J Biol Chem. 2003 Oct 10; 278(41):39921-30. PMID: 12869548.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  30. Apicelli AJ, Uhlmann EJ, Baldwin RL, Ding H, Nagy A, Guha A, Gutmann DH. Role of the Rap1 GTPase in astrocyte growth regulation. Glia. 2003 May; 42(3):225-34. PMID: 12673829.
    Citations: 5     Fields:    Translation:AnimalsCells
  31. Lau N, Uhlmann EJ, Von Lintig FC, Nagy A, Boss GR, Gutmann DH, Guha A. Rap1 activity is elevated in malignant astrocytomas independent of tuberous sclerosis complex-2 gene expression. Int J Oncol. 2003 Jan; 22(1):195-200. PMID: 12469204.
    Citations: 2     Fields:    Translation:Humans
  32. Uhlmann EJ, Wong M, Baldwin RL, Bajenaru ML, Onda H, Kwiatkowski DJ, Yamada K, Gutmann DH. Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures. Ann Neurol. 2002 Sep; 52(3):285-96. PMID: 12205640.
    Citations: 139     Fields:    Translation:AnimalsCells
  33. Uhlmann EJ, Apicelli AJ, Baldwin RL, Burke SP, Bajenaru ML, Onda H, Kwiatkowski D, Gutmann DH. Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells. Oncogene. 2002 Jun 06; 21(25):4050-9. PMID: 12037687.
    Citations: 21     Fields:    Translation:AnimalsCells
  34. Uhlmann EJ, Hock KG, Issitt C, Sneeringer MR, Cervelli DR, Gorman RT, Scott MG. Reference intervals for plasma cystatin C in healthy volunteers and renal patients, as measured by the Dade Behring BN II System, and correlation with creatinine. Clin Chem. 2001 Nov; 47(11):2031-3. PMID: 11673373.
    Citations: 11     Fields:    Translation:Humans
  35. Kyin R, Hua Y, Baybis M, Scheithauer B, Kolson D, Uhlmann E, Gutmann D, Crino PB. Differential cellular expression of neurotrophins in cortical tubers of the tuberous sclerosis complex. Am J Pathol. 2001 Oct; 159(4):1541-54. PMID: 11583980; PMCID: PMC1850517.
    Citations: 8     Fields:    Translation:HumansCells
  36. Uhlmann EJ, Isgriggs E, Wallhermfechtel M, Goodnough LT. Prestorage universal WBC reduction of RBC units does not affect the incidence of transfusion reactions. Transfusion. 2001 Aug; 41(8):997-1000. PMID: 11493730.
    Citations: 13     Fields:    Translation:HumansCells
  37. Arbiser JL, Yeung R, Weiss SW, Arbiser ZK, Amin MB, Cohen C, Frank D, Mahajan S, Herron GS, Yang J, Onda H, Zhang HB, Bai X, Uhlmann E, Loehr A, Northrup H, Au P, Davis I, Fisher DE, Gutmann DH. The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms. Am J Pathol. 2001 Aug; 159(2):483-91. PMID: 11485907; PMCID: PMC1850536.
    Citations: 19     Fields:    Translation:HumansCells
  38. Uhlmann EJ, Gutmann DH. Tumor suppressor gene regulation of cell growth: recent insights into neurofibromatosis 1 and 2 gene function. Cell Biochem Biophys. 2001; 34(1):61-78. PMID: 11394441.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  39. Rait A, Pirollo K, Will DW, Peyman A, Rait V, Uhlmann E, Chang EH. 3'-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells. Bioconjug Chem. 2000 Mar-Apr; 11(2):153-60. PMID: 10725091.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  40. Uhlmann EJ, Subramanian T, Vater CA, Lutz R, Chinnadurai G. A potent cell death activity associated with transient high level expression of BCL-2. J Biol Chem. 1998 Jul 10; 273(28):17926-32. PMID: 9651399.
    Citations: 10     Fields:    Translation:HumansCells
  41. Uhlmann EJ, D'Sa-Eipper C, Subramanian T, Wagner AJ, Hay N, Chinnadurai G. Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation. Cancer Res. 1996 Jun 01; 56(11):2506-9. PMID: 8653686.
    Citations: 11     Fields:    Translation:HumansCells
  42. Schaeper U, Boyd JM, Verma S, Uhlmann E, Subramanian T, Chinnadurai G. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc Natl Acad Sci U S A. 1995 Nov 07; 92(23):10467-71. PMID: 7479821; PMCID: PMC40632.
    Citations: 110     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.