Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Raphael Bueno, M.D.

Title
Institution
Department
Address
Phone
Fax

Mentoring
completed student projects
From OR to bench: Identification of variables affecting success in generating patient derived organotypic spheroids (PDOTS)
Soma Weiss, 09/01/17 - 03/30/19

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01EB025964 (JAGADEESAN, JAYENDER) Sep 15, 2018 - May 31, 2022
    NIH/NIBIB
    Lung Navigation System for Localizing and Resecting Nodules
    Role: Co-Principal Investigator
  2. R01CA120528 (BUENO, RAPHAEL) Apr 7, 2006 - Jul 31, 2022
    NIH/NCI
    Prospective Validation of Prognostic and Predictive Molecular tests in Mesothelioma
    Role: Principal Investigator
  3. R33CA100315 (BUENO, RAPHAEL) Aug 1, 2004 - Jul 31, 2008
    NIH/NCI
    Gene Ratio Based Prognosis in Mesothelioma
    Role: Principal Investigator
  4. R21CA100315 (BUENO, RAPHAEL) Aug 1, 2004 - Jul 31, 2005
    NIH/NCI
    Gene Ratio Based Prognosis in Mesothelioma
    Role: Principal Investigator
  5. R21CA098501 (BUENO, RAPHAEL) Jul 1, 2003 - Jun 30, 2006
    NIH/NCI
    Gene Ratios for Lung Cancer Detection and Prognosis
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zilionis R, Engblom C, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ, Klein AM. Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species. Immunity. 2019 Apr 05. PMID: 30979687.
    Citations:    
  2. Cooley ME, Blonquist TM, Hong F, Nayak MM, Crouter SE, Hayman LL, Jaklitsch MT, Emmons KM, Bueno R. The effect of a lifestyle risk reduction intervention on lifestyle adherence and health-related quality of life in nonsmall cell lung cancer survivors: Feasibility study outcomes. Psychooncology. 2019 Apr; 28(4):920-923. PMID: 30673155.
    Citations:    Fields:    
  3. Follo C, Barbone D, Richards WG, Bueno R, Courtney Broaddus V. Autophagy in 3D In Vitro and Ex Vivo Cancer Models. Methods Mol Biol. 2019; 1880:491-510. PMID: 30610717.
    Citations:    Fields:    
  4. Hmeljak J, Sanchez-Vega F, Hoadley KA, Shih J, Stewart C, Heiman D, Tarpey P, Danilova L, Drill E, Gibb EA, Bowlby R, Kanchi R, Osmanbeyoglu HU, Sekido Y, Takeshita J, Newton Y, Graim K, Gupta M, Gay CM, Diao L, Gibbs DL, Thorsson V, Iype L, Kantheti H, Severson DT, Ravegnini G, Desmeules P, Jungbluth AA, Travis WD, Dacic S, Chirieac LR, Galateau-Sallé F, Fujimoto J, Husain AN, Silveira HC, Rusch VW, Rintoul RC, Pass H, Kindler H, Zauderer MG, Kwiatkowski DJ, Bueno R, Tsao AS, Creaney J, Lichtenberg T, Leraas K, Bowen J, Felau I, Zenklusen JC, Akbani R, Cherniack AD, Byers LA, Noble MS, Fletcher JA, Robertson AG, Shen R, Aburatani H, Robinson BW, Campbell P, Ladanyi M. Integrative Molecular Characterization of Malignant Pleural Mesothelioma. Cancer Discov. 2018 12; 8(12):1548-1565. PMID: 30322867.
    Citations:    Fields:    
  5. Tsao AS, Lindwasser OW, Adjei AA, Adusumilli PS, Beyers ML, Blumenthal GM, Bueno R, Burt BM, Carbone M, Dahlberg SE, de Perrot M, Fennell DA, Friedberg J, Gill RR, Gomez DR, Harpole DH, Hassan R, Hesdorffer M, Hirsch FR, Hmeljak J, Kindler HL, Korn EL, Liu G, Mansfield AS, Nowak AK, Pass HI, Peikert T, Rimner A, Robinson BWS, Rosenzweig KE, Rusch VW, Salgia R, Sepesi B, Simone CB, Sridhara R, Szlosarek P, Taioli E, Tsao MS, Yang H, Zauderer MG, Malik SM. Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation. J Thorac Oncol. 2018 11; 13(11):1655-1667. PMID: 30266660.
    Citations:    Fields:    
  6. Yu H, Chen Z, Ballman KV, Watson MA, Govindan R, Lanc I, Beer DG, Bueno R, Chirieac LR, Chui MH, Chen G, Franklin WA, Gandara DR, Genova C, Brovsky KA, Joshi MM, Merrick DT, Richards WG, Rivard CJ, Harpole DH, Tsao MS, van Bokhoven A, Shepherd FA, Hirsch FR. Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. J Thorac Oncol. 2019 Jan; 14(1):25-36. PMID: 30253973.
    Citations:    Fields:    
  7. Bueno R, Opitz I. Surgery in Malignant Pleural Mesothelioma. J Thorac Oncol. 2018 11; 13(11):1638-1654. PMID: 30121394.
    Citations:    Fields:    
  8. Kindler HL, Rusch V, Bueno R, Ismaila N, Pass H, Sterman D, Hassan R. Reply to D. de Fonseka et al. J Clin Oncol. 2018 Sep 10; 36(26):2746-2747. PMID: 29902108.
    Citations:    Fields:    
  9. Rodríguez M, Mallidi HR, da Silva A, Bueno R. Recurrence of Pericardial Mesothelioma Affecting the Myocardium After Pericardial Resection. Ann Thorac Surg. 2018 Nov; 106(5):e243-e245. PMID: 29792828.
    Citations:    Fields:    
  10. Morrow JD, Glass K, Cho MH, Hersh CP, Pinto-Plata V, Celli B, Marchetti N, Criner G, Bueno R, Washko G, Choi AMK, Quackenbush J, Silverman EK, DeMeo DL. Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci. Am J Respir Crit Care Med. 2018 May 15; 197(10):1275-1284. PMID: 29313708.
    Citations:    Fields:    
  11. Burt BM, Richards WG, Lee HS, Bartel S, Dasilva MC, Gill RR, Jaklitsch MT, Johnson BE, Swanson SJ, Bueno R, Sugarbaker DJ. A Phase I Trial of Surgical Resection and Intraoperative Hyperthermic Cisplatin and Gemcitabine for Pleural Mesothelioma. J Thorac Oncol. 2018 09; 13(9):1400-1409. PMID: 29753120.
    Citations:    Fields:    
  12. Gill RR, Yeap BY, Bueno R, Richards WG. Quantitative Clinical Staging for Patients With Malignant Pleural Mesothelioma. J Natl Cancer Inst. 2018 03 01; 110(3):258-264. PMID: 29931180.
    Citations:    Fields:    
  13. Lapidot M, Freyaldenhoven S, Bueno R. New concepts in the treatment of malignant pleural mesothelioma. J Thorac Dis. 2018 Mar; 10(3):1283-1285. PMID: 29708159.
    Citations:    
  14. Hung YP, Dong F, Watkins JC, Nardi V, Bueno R, Dal Cin P, Godleski JJ, Crum CP, Chirieac LR. Identification of ALK Rearrangements in Malignant Peritoneal Mesothelioma. JAMA Oncol. 2018 Feb 01; 4(2):235-238. PMID: 28910456.
    Citations: 6     Fields:    
  15. Kindler HL, Ismaila N, Armato SG, Bueno R, Hesdorffer M, Jahan T, Jones CM, Miettinen M, Pass H, Rimner A, Rusch V, Sterman D, Thomas A, Hassan R. Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol. 2018 May 01; 36(13):1343-1373. PMID: 29346042.
    Citations: 15     Fields:    
  16. Morrow JD, Cho MH, Platig J, Zhou X, DeMeo DL, Qiu W, Celli B, Marchetti N, Criner GJ, Bueno R, Washko GR, Glass K, Quackenbush J, Silverman EK, Hersh CP. Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease. Hum Genomics. 2018 01 15; 12(1):1. PMID: 29335020.
    Citations:    Fields:    Translation:Humans
  17. Follo C, Cheng Y, Richards WG, Bueno R, Broaddus VC. Inhibition of autophagy initiation potentiates chemosensitivity in mesothelioma. Mol Carcinog. 2018 03; 57(3):319-332. PMID: 29073722.
    Citations:    Fields:    Translation:HumansCells
  18. Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 02; 8(2):196-215. PMID: 29101162.
    Citations: 4     Fields:    
  19. Deng J, Wang ES, Jenkins RW, Li S, Dries R, Yates K, Chhabra S, Huang W, Liu H, Aref AR, Ivanova E, Paweletz CP, Bowden M, Zhou CW, Herter-Sprie GS, Sorrentino JA, Bisi JE, Lizotte PH, Merlino AA, Quinn MM, Bufe LE, Yang A, Zhang Y, Zhang H, Gao P, Chen T, Cavanaugh ME, Rode AJ, Haines E, Roberts PJ, Strum JC, Richards WG, Lorch JH, Parangi S, Gunda V, Boland GM, Bueno R, Palakurthi S, Freeman GJ, Ritz J, Haining WN, Sharpless NE, Arthanari H, Shapiro GI, Barbie DA, Gray NS, Wong KK. CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation. Cancer Discov. 2018 02; 8(2):216-233. PMID: 29101163.
    Citations: 4     Fields:    
  20. White A, Kucukak S, Bueno R, Servais E, Lee DN, Colson Y, Jaklitsch M, McNamee C, Mentzer S, Wee J, Swanson SJ. Pneumonectomy is safe and effective for non-small cell lung cancer following induction therapy. J Thorac Dis. 2017 Nov; 9(11):4447-4453. PMID: 29268514.
    Citations:    
  21. Li M, Narayan V, Gill RR, Jagannathan JP, Barile MF, Gao F, Bueno R, Jayender J. Computer-Aided Diagnosis of Ground-Glass Opacity Nodules Using Open-Source Software for Quantifying Tumor Heterogeneity. AJR Am J Roentgenol. 2017 Dec; 209(6):1216-1227. PMID: 29045176.
    Citations: 1     Fields:    Translation:Humans
  22. Vivero M, Bueno R, Chirieac LR. Clinicopathologic and genetic characteristics of young patients with pleural diffuse malignant mesothelioma. Mod Pathol. 2018 01; 31(1):122-131. PMID: 28884745.
    Citations: 1     Fields:    Translation:Humans
  23. Agoston AT, Srivastava A, Zheng Y, Bueno R, Odze RD, Szallasi Z. Paraneoplastic thrombocytosis is associated with increased mortality and increased rate of lymph node metastasis in oesophageal adenocarcinoma. Pathology. 2017 Aug; 49(5):471-475. PMID: 28668174.
    Citations:    Fields:    Translation:Humans
  24. Blok AC, Blonquist TM, Nayak MM, Somayaji D, Crouter SE, Hayman LL, Colson YL, Bueno R, Emmons KM, Cooley ME. Feasibility and acceptability of "healthy directions" a lifestyle intervention for adults with lung cancer. Psychooncology. 2018 01; 27(1):250-257. PMID: 28426922.
    Citations:    Fields:    Translation:Humans
  25. Akbay EA, Koyama S, Liu Y, Dries R, Bufe LE, Silkes M, Alam MM, Magee DM, Jones R, Jinushi M, Kulkarni M, Carretero J, Wang X, Warner-Hatten T, Cavanaugh JD, Osa A, Kumanogoh A, Freeman GJ, Awad MM, Christiani DC, Bueno R, Hammerman PS, Dranoff G, Wong KK. Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade. J Thorac Oncol. 2017 08; 12(8):1268-1279. PMID: 28483607.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  26. Drage MG, Tippayawong M, Agoston AT, Zheng Y, Bueno R, Hornick JL, Odze RD, Srivastava A. Morphological Features and Prognostic Significance of ARID1A-Deficient Esophageal Adenocarcinomas. Arch Pathol Lab Med. 2017 Jul; 141(7):970-977. PMID: 28440661.
    Citations:    Fields:    Translation:Humans
  27. Morrow JD, Zhou X, Lao T, Jiang Z, DeMeo DL, Cho MH, Qiu W, Cloonan S, Pinto-Plata V, Celli B, Marchetti N, Criner GJ, Bueno R, Washko GR, Glass K, Quackenbush J, Choi AM, Silverman EK, Hersh CP. Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue. Sci Rep. 2017 03 13; 7:44232. PMID: 28287180.
    Citations: 7     Fields:    Translation:HumansAnimalsCTClinical Trials
  28. White A, Bueno R. Long-Term Management Challenges in Esophageal Atresia. Curr Treat Options Gastroenterol. 2017 Mar; 15(1):46-52. PMID: 28120278.
    Citations:    
  29. Wee JO, Bueno R, Swanson SJ. Minimally invasive esophagectomy: the Brigham and Women's Hospital experience. Ann Cardiothorac Surg. 2017 Mar; 6(2):175-178. PMID: 28447007.
    Citations:    
  30. De Rienzo A, Cook RW, Wilkinson J, Gustafson CE, Amin W, Johnson CE, Oelschlager KM, Maetzold DJ, Stone JF, Feldman MD, Becich MJ, Yeap BY, Richards WG, Bueno R. Validation of a Gene Expression Test for Mesothelioma Prognosis in Formalin-Fixed Paraffin-Embedded Tissues. J Mol Diagn. 2017 01; 19(1):65-71. PMID: 27863259.
    Citations: 2     Fields:    Translation:HumansCells
  31. Awad MM, Jones RE, Liu H, Lizotte PH, Ivanova EV, Kulkarni M, Herter-Sprie GS, Liao X, Santos AA, Bittinger MA, Keogh L, Koyama S, Almonte C, English JM, Barlow J, Richards WG, Barbie DA, Bass AJ, Rodig SJ, Hodi FS, Wucherpfennig KW, Jänne PA, Sholl LM, Hammerman PS, Wong KK, Bueno R. Cytotoxic T Cells in PD-L1-Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors. Cancer Immunol Res. 2016 12; 4(12):1038-1048. PMID: 27856426.
    Citations: 10     Fields:    Translation:HumansCells
  32. Morrow JD, Cho MH, Hersh CP, Pinto-Plata V, Celli B, Marchetti N, Criner G, Bueno R, Washko G, Glass K, Choi AMK, Quackenbush J, Silverman EK, DeMeo DL. DNA methylation profiling in human lung tissue identifies genes associated with COPD. Epigenetics. 2016 Oct 02; 11(10):730-739. PMID: 27564456.
    Citations: 6     Fields:    
  33. Lizotte PH, Ivanova EV, Awad MM, Jones RE, Keogh L, Liu H, Dries R, Almonte C, Herter-Sprie GS, Santos A, Feeney NB, Paweletz CP, Kulkarni MM, Bass AJ, Rustgi AK, Yuan GC, Kufe DW, Jänne PA, Hammerman PS, Sholl LM, Hodi FS, Richards WG, Bueno R, English JM, Bittinger MA, Wong KK. Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes. JCI Insight. 2016 09 08; 1(14):e89014. PMID: 27699239.
    Citations: 14     Fields:    Translation:HumansCells
  34. Lizotte PH, Jones RE, Keogh L, Ivanova E, Liu H, Awad MM, Hammerman PS, Gill RR, Richards WG, Barbie DA, Bass AJ, Bueno R, English JM, Bittinger M, Wong KK. Fine needle aspirate flow cytometric phenotyping characterizes immunosuppressive nature of the mesothelioma microenvironment. Sci Rep. 2016 08 19; 6:31745. PMID: 27539742.
    Citations: 5     Fields:    Translation:HumansCells
  35. Cleary JM, Mamon HJ, Szymonifka J, Bueno R, Choi N, Donahue DM, Fidias PM, Gaissert HA, Jaklitsch MT, Kulke MH, Lynch TP, Mentzer SJ, Meyerhardt JA, Swanson RS, Wain J, Fuchs CS, Enzinger PC. Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer. BMC Cancer. 2016 07 13; 16:468. PMID: 27412386.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  36. Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, Pinto-Plata VM, Criner GJ, Marchetti N, Bueno R, Agustí A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Zhou X, Laird NM, Lin X, Beaty TH, Silverman EK, Cho MH. Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 07 01; 194(1):48-57. PMID: 26771213.
    Citations: 10     Fields:    Translation:Humans
  37. Zheng Y, Jaklitsch MT, Bueno R. Neoadjuvant Therapy in Non-Small Cell Lung Cancer. Surg Oncol Clin N Am. 2016 07; 25(3):567-84. PMID: 27261916.
    Citations: 3     Fields:    Translation:Humans
  38. Meerang M, Bérard K, Friess M, Bitanihirwe BK, Soltermann A, Vrugt B, Felley-Bosco E, Bueno R, Richards WG, Seifert B, Stahel R, Weder W, Opitz I. Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma. Mol Oncol. 2016 10; 10(8):1255-65. PMID: 27378628.
    Citations: 11     Fields:    Translation:HumansCells
  39. Qiao D, Lange C, Beaty TH, Crapo JD, Barnes KC, Bamshad M, Hersh CP, Morrow J, Pinto-Plata VM, Marchetti N, Bueno R, Celli BR, Criner GJ, Silverman EK, Cho MH. Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 06 15; 193(12):1353-63. PMID: 26736064.
    Citations: 12     Fields:    Translation:Humans
  40. Follo C, Barbone D, Richards WG, Bueno R, Broaddus VC. Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome. Autophagy. 2016 07 02; 12(7):1180-94. PMID: 27097020.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  41. Barbone D, Van Dam L, Follo C, Jithesh PV, Zhang SD, Richards WG, Bueno R, Fennell DA, Broaddus VC. Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma. PLoS One. 2016; 11(3):e0150044. PMID: 26982031.
    Citations: 3     Fields:    Translation:HumansCells
  42. Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S. Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations. Nat Genet. 2016 Apr; 48(4):407-16. PMID: 26928227.
    Citations: 85     Fields:    Translation:HumansCells
  43. Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, Gandhi L, Redig AJ, Rodig SJ, Asahina H, Jones RE, Kulkarni MM, Kuraguchi M, Palakurthi S, Fecci PE, Johnson BE, Janne PA, Engelman JA, Gangadharan SP, Costa DB, Freeman GJ, Bueno R, Hodi FS, Dranoff G, Wong KK, Hammerman PS. Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints. Nat Commun. 2016 Feb 17; 7:10501. PMID: 26883990.
    Citations: 153     Fields:    Translation:HumansAnimals
  44. De Rienzo A, Archer MA, Yeap BY, Dao N, Sciaranghella D, Sideris AC, Zheng Y, Holman AG, Wang YE, Dal Cin PS, Fletcher JA, Rubio R, Croft L, Quackenbush J, Sugarbaker PE, Munir KJ, Battilana JR, Gustafson CE, Chirieac LR, Ching SM, Wong J, Tay LC, Rudd S, Hercus R, Sugarbaker DJ, Richards WG, Bueno R. Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma. Cancer Res. 2016 Jan 15; 76(2):319-28. PMID: 26554828.
    Citations: 8     Fields:    Translation:Humans
  45. Bravo Iñiguez CE, Armstrong KW, Cooper Z, Weissman JS, Ducko CT, Wee JO, Martinez MP, Bueno R, Jaklitsch MT, Wiener DC. Thirty-Day Mortality After Lobectomy in Elderly Patients Eligible for Lung Cancer Screening. Ann Thorac Surg. 2016 Feb; 101(2):541-6. PMID: 26603020.
    Citations: 2     Fields:    Translation:Humans
  46. Rao M, Atay SM, Shukla V, Hong Y, Upham T, Ripley RT, Hong JA, Zhang M, Reardon E, Fetsch P, Miettinen M, Li X, Peer CJ, Sissung T, Figg WD, De Rienzo A, Bueno R, Schrump DS. Mithramycin Depletes Specificity Protein 1 and Activates p53 to Mediate Senescence and Apoptosis of Malignant Pleural Mesothelioma Cells. Clin Cancer Res. 2016 Mar 01; 22(5):1197-210. PMID: 26459178.
    Citations: 6     Fields:    Translation:HumansAnimals
  47. Barbone D, Follo C, Echeverry N, Gerbaudo VH, Klabatsa A, Bueno R, Felley-Bosco E, Broaddus VC. Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models. PLoS One. 2015; 10(8):e0134825. PMID: 26284517.
    Citations: 1     Fields:    Translation:HumansCells
  48. Mody GN, Bravo Iñiguez C, Armstrong K, Perez Martinez M, Ferrone M, Bono C, Chi JH, Wee JO, Lebenthal A, Swanson SJ, Colson YL, Bueno R, Jaklitsch MT. Early Surgical Outcomes of En Bloc Resection Requiring Vertebrectomy for Malignancy Invading the Thoracic Spine. Ann Thorac Surg. 2016 Jan; 101(1):231-6; discussion 236-7. PMID: 26277561.
    Citations: 2     Fields:    Translation:Humans
  49. Agoston AT, Zheng Y, Bueno R, Lauwers GY, Odze RD, Srivastava A. Predictors of Disease Recurrence and Survival in Esophageal Adenocarcinomas With Complete Response to Neoadjuvant Therapy. Am J Surg Pathol. 2015 Aug; 39(8):1085-92. PMID: 26076061.
    Citations: 5     Fields:    Translation:Humans
  50. Spector R, Zheng Y, Yeap BY, Wee JO, Lebenthal A, Swanson SJ, Marchosky DE, Enzinger PC, Mamon HJ, Lerut A, Odze R, Srivastava A, Agoston AT, Tippayawang M, Bueno R. The 3-Hole Minimally Invasive Esophagectomy: A Safe Procedure Following Neoadjuvant Chemotherapy and Radiation. Semin Thorac Cardiovasc Surg. 2015; 27(2):205-15. PMID: 26686448.
    Citations: 3     Fields:    Translation:Humans
  51. Gill RR, Zheng Y, Barlow JS, Jayender J, Girard EE, Hartigan PM, Chirieac LR, Belle-King CJ, Murray K, Sears C, Wee JO, Jaklitsch MT, Colson YL, Bueno R. Image-guided video assisted thoracoscopic surgery (iVATS) - phase I-II clinical trial. J Surg Oncol. 2015 Jul; 112(1):18-25. PMID: 26031893.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  52. Zheng Y, Bueno R. Commercially available prognostic molecular models in early-stage lung cancer: a review of the Pervenio Lung RS and Myriad myPlan Lung Cancer tests. Expert Rev Mol Diagn. 2015 May; 15(5):589-96. PMID: 25896578.
    Citations: 7     Fields:    Translation:Humans
  53. Baldini EH, Richards WG, Gill RR, Goodman BM, Winfrey OK, Eisen HM, Mak RH, Chen AB, Kozono DE, Bueno R, Sugarbaker DJ. Updated patterns of failure after multimodality therapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2015 May; 149(5):1374-81. PMID: 25772281.
    Citations: 8     Fields:    Translation:Humans
  54. Bueno R, Hughes E, Wagner S, Gutin AS, Lanchbury JS, Zheng Y, Archer MA, Gustafson C, Jones JT, Rushton K, Saam J, Kim E, Barberis M, Wistuba I, Wenstrup RJ, Wallace WA, Hartman AR, Harrison DJ. Validation of a molecular and pathological model for five-year mortality risk in patients with early stage lung adenocarcinoma. J Thorac Oncol. 2015 Jan; 10(1):67-73. PMID: 25396679.
    Citations: 12     Fields:    Translation:Humans
  55. Opitz I, Bueno R, Lim E, Pass H, Pastorino U, Boeri M, Rocco G. Corrigendum to 'Biomolecular and clinical practice in malignant pleural mesothelioma and lung cancer: what thoracic surgeons should know'. Eur J Cardiothorac Surg. 2015 Jan; 47(1):200. PMID: 25694655.
    Citations:    Fields:    
  56. Sugarbaker DJ, Richards WG, Bueno R. Extrapleural pneumonectomy in the treatment of epithelioid malignant pleural mesothelioma: novel prognostic implications of combined N1 and N2 nodal involvement based on experience in 529 patients. Ann Surg. 2014 Oct; 260(4):577-80; discussion 580-2. PMID: 25203873.
    Citations: 16     Fields:    Translation:Humans
  57. Wakeam E, Wee J, Lebenthal A, Ali SO, Gilbert RJ, Bueno R. Does BMI predict recurrence or complications after reoperative reflux surgery? Review of a single center's experience and a comparison of outcomes. J Gastrointest Surg. 2014 Nov; 18(11):1965-73. PMID: 25227639.
    Citations: 2     Fields:    Translation:Humans
  58. Kanteti R, Dhanasingh I, Kawada I, Lennon FE, Arif Q, Bueno R, Hasina R, Husain AN, Vigneswaran W, Seiwert T, Kindler HL, Salgia R. MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma. PLoS One. 2014; 9(9):e105919. PMID: 25221930.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  59. Tempany CM, Jayender J, Kapur T, Bueno R, Golby A, Agar N, Jolesz FA. Multimodal imaging for improved diagnosis and treatment of cancers. Cancer. 2015 Mar 15; 121(6):817-27. PMID: 25204551.
    Citations: 9     Fields:    Translation:Humans
  60. Doyle LA, Wong KK, Bueno R, Dal Cin P, Fletcher JA, Sholl LM, Kuo F. Ewing sarcoma mimicking atypical carcinoid tumor: detection of unexpected genomic alterations demonstrates the use of next generation sequencing as a diagnostic tool. Cancer Genet. 2014 Jul-Aug; 207(7-8):335-9. PMID: 25441687.
    Citations: 6     Fields:    Translation:Humans
  61. Rahaghi FN, Lazea D, Dihya S, San José Estépar R, Bueno R, Sugarbaker D, Frendl G, Washko GR. Preoperative pulmonary vascular morphology and its relationship to postpneumonectomy hemodynamics. Acad Radiol. 2014 Jun; 21(6):704-10. PMID: 24809312.
    Citations:    Fields:    Translation:Humans
  62. Shtivelman E, Hensing T, Simon GR, Dennis PA, Otterson GA, Bueno R, Salgia R. Molecular pathways and therapeutic targets in lung cancer. Oncotarget. 2014 Mar 30; 5(6):1392-433. PMID: 24722523.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  63. Opitz I, Bueno R, Lim E, Pass H, Pastorino U, Boeri M, Rocco G. Biomolecular and clinical practice in malignant pleural mesothelioma and lung cancer: what thoracic surgeons should know. Eur J Cardiothorac Surg. 2014 Oct; 46(4):602-6. PMID: 24623168.
    Citations:    Fields:    Translation:Humans
  64. Boskovski MT, Gosev I, Bueno R, Steigner ML, Saboo S, Aranki SF. Aneurysm of a saphenous vein aortocoronary graft. J Card Surg. 2015 Mar; 30(3):270-1. PMID: 24512216.
    Citations:    Fields:    Translation:Humans
  65. De Rienzo A, Yeap BY, Cibas ES, Richards WG, Dong L, Gill RR, Sugarbaker DJ, Bueno R. Gene expression ratio test distinguishes normal lung from lung tumors in solid tissue and FNA biopsies. J Mol Diagn. 2014 Mar; 16(2):267-72. PMID: 24412526.
    Citations: 4     Fields:    Translation:Humans
  66. Mohiuddin K, Haneuse S, Sofer T, Gill R, Jaklitsch MT, Colson YL, Wee J, Bueno R, Mentzer SJ, Sugarbaker DJ, Swanson SJ. Relationship between margin distance and local recurrence among patients undergoing wedge resection for small (=2 cm) non-small cell lung cancer. J Thorac Cardiovasc Surg. 2014 Apr; 147(4):1169-75; discussion 1175-7. PMID: 24507406.
    Citations: 16     Fields:    Translation:Humans
  67. Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF, Quintana C, Osorio JC, Wang Z, Zhao Y, Lawler LA, Christie JD, Meyer NJ, Mc Causland FR, Waikar SS, Waxman AB, Chung RT, Bueno R, Rosas IO, Fredenburgh LE, Baron RM, Christiani DC, Hunninghake GM, Choi AM. Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation. PLoS Med. 2013 Dec; 10(12):e1001577; discussion e1001577. PMID: 24391478.
    Citations: 75     Fields:    Translation:Humans
  68. Bueno RC, Canevari RA, Villacis RA, Domingues MA, Caldeira JR, Rocha RM, Drigo SA, Rogatto SR. ATM down-regulation is associated with poor prognosis in sporadic breast carcinomas. Ann Oncol. 2014 Jan; 25(1):69-75. PMID: 24285016.
    Citations: 15     Fields:    Translation:HumansCells
  69. Chirieac LR, Barletta JA, Yeap BY, Richards WG, Tilleman T, Bueno R, Baldini EH, Godleski J, Sugarbaker DJ. Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma. J Clin Oncol. 2013 Dec 20; 31(36):4544-9. PMID: 24248693.
    Citations: 12     Fields:    Translation:Humans
  70. Guo Y, Chirieac LR, Bueno R, Pass H, Wu W, Malinowska IA, Kwiatkowski DJ. Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma. Oncogene. 2014 Jun 12; 33(24):3151-60. PMID: 23851502.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  71. Oxman DA, Issa NC, Marty FM, Patel A, Panizales CZ, Johnson NN, Licona JH, McKenna SS, Frendl G, Mentzer SJ, Jaklitsch MT, Bueno R, Colson Y, Swanson SJ, Sugarbaker DJ, Baden LR. Postoperative antibacterial prophylaxis for the prevention of infectious complications associated with tube thoracostomy in patients undergoing elective general thoracic surgery: a double-blind, placebo-controlled, randomized trial. JAMA Surg. 2013 May; 148(5):440-6. PMID: 23325435.
    Citations: 3     Fields:    Translation:Humans
  72. De Rienzo A, Richards WG, Yeap BY, Coleman MH, Sugarbaker PE, Chirieac LR, Wang YE, Quackenbush J, Jensen RV, Bueno R. Sequential binary gene ratio tests define a novel molecular diagnostic strategy for malignant pleural mesothelioma. Clin Cancer Res. 2013 May 01; 19(9):2493-502. PMID: 23493352.
    Citations: 4     Fields:    Translation:HumansCells
  73. Lee MS, Mamon HJ, Hong TS, Choi NC, Fidias PM, Kwak EL, Meyerhardt JA, Ryan DP, Bueno R, Donahue DM, Jaklitsch MT, Lanuti M, Rattner DW, Fuchs CS, Enzinger PC. Preoperative cetuximab, irinotecan, cisplatin, and radiation therapy for patients with locally advanced esophageal cancer. Oncologist. 2013; 18(3):281-7. PMID: 23429739.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  74. Sugarbaker DJ, Gill RR, Yeap BY, Wolf AS, DaSilva MC, Baldini EH, Bueno R, Richards WG. Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection. J Thorac Cardiovasc Surg. 2013 Apr; 145(4):955-963. PMID: 23434448.
    Citations: 26     Fields:    Translation:Humans
  75. Rusch V, Baldini EH, Bueno R, De Perrot M, Flores R, Hasegawa S, Klepetko W, Krug L, Lang-Lazdunski L, Pass H, Weder W, Sugarbaker DJ. The role of surgical cytoreduction in the treatment of malignant pleural mesothelioma: meeting summary of the International Mesothelioma Interest Group Congress, September 11-14, 2012, Boston, Mass. J Thorac Cardiovasc Surg. 2013 Apr; 145(4):909-910. PMID: 23415687.
    Citations: 34     Fields:    Translation:Humans
  76. Barbone D, Cheung P, Battula S, Busacca S, Gray SG, Longley DB, Bueno R, Sugarbaker DJ, Fennell DA, Broaddus VC. Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression. PLoS One. 2012; 7(12):e52753. PMID: 23300762.
    Citations: 12     Fields:    Translation:HumansCells
  77. Boylan AM, Wang XF, Ko R, Watson PM, Gu L, Harpole D, Bueno R, Kelly R, Kohman L, Kratzke R. Detection of human telomerase reverse transcriptase mRNA in cells obtained by lavage of the pleura is not associated with worse outcome in patients with stage I/II non-small cell lung cancer: results from Cancer and Leukemia Group B 159902. J Thorac Cardiovasc Surg. 2013 Jul; 146(1):206-11. PMID: 23026566.
    Citations:    Fields:    Translation:Humans
  78. Ersoy H, Steigner ML, Coyner KB, Gerhard-Herman MD, Rybicki FJ, Bueno R, Nguyen LL. Vascular thoracic outlet syndrome: protocol design and diagnostic value of contrast-enhanced 3D MR angiography and equilibrium phase imaging on 1.5- and 3-T MRI scanners. AJR Am J Roentgenol. 2012 May; 198(5):1180-7. PMID: 22528911.
    Citations: 4     Fields:    Translation:Humans
  79. West L, Vidwans SJ, Campbell NP, Shrager J, Simon GR, Bueno R, Dennis PA, Otterson GA, Salgia R. A novel classification of lung cancer into molecular subtypes. PLoS One. 2012; 7(2):e31906. PMID: 22363766.
    Citations: 30     Fields:    Translation:HumansCells
  80. Gill RR, Richards WG, Yeap BY, Matsuoka S, Wolf AS, Gerbaudo VH, Bueno R, Sugarbaker DJ, Hatabu H. Epithelial malignant pleural mesothelioma after extrapleural pneumonectomy: stratification of survival with CT-derived tumor volume. AJR Am J Roentgenol. 2012 Feb; 198(2):359-63. PMID: 22268178.
    Citations: 14     Fields:    Translation:Humans
  81. Burt BM, Bader A, Winter D, Rodig SJ, Bueno R, Sugarbaker DJ. Expression of interleukin-4 receptor alpha in human pleural mesothelioma is associated with poor survival and promotion of tumor inflammation. Clin Cancer Res. 2012 Mar 15; 18(6):1568-77. PMID: 22261806.
    Citations: 12     Fields:    Translation:HumansCells
  82. Cooley ME, Wang Q, Johnson BE, Catalano P, Haddad RI, Bueno R, Emmons KM. Factors associated with smoking abstinence among smokers and recent-quitters with lung and head and neck cancer. Lung Cancer. 2012 May; 76(2):144-9. PMID: 22093155.
    Citations: 11     Fields:    Translation:Humans
  83. Wolf AS, Richards WG, Jaklitsch MT, Gill R, Chirieac LR, Colson YL, Mohiuddin K, Mentzer SJ, Bueno R, Sugarbaker DJ, Swanson SJ. Lobectomy versus sublobar resection for small (2 cm or less) non-small cell lung cancers. Ann Thorac Surg. 2011 Nov; 92(5):1819-23; discussion 1824-5. PMID: 22051277.
    Citations: 33     Fields:    Translation:Humans
  84. Kemp CD, Rao M, Xi S, Inchauste S, Mani H, Fetsch P, Filie A, Zhang M, Hong JA, Walker RL, Zhu YJ, Ripley RT, Mathur A, Liu F, Yang M, Meltzer PA, Marquez VE, De Rienzo A, Bueno R, Schrump DS. Polycomb repressor complex-2 is a novel target for mesothelioma therapy. Clin Cancer Res. 2012 Jan 01; 18(1):77-90. PMID: 22028491.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  85. Coleman MH, Bueno R. Role of adjuvant chemotherapy in NSCLC (stages I to III). Surg Oncol Clin N Am. 2011 Oct; 20(4):757-67. PMID: 21986270.
    Citations: 5     Fields:    Translation:Humans
  86. Burt BM, Ocejo S, Mery CM, Dasilva M, Bueno R, Sugarbaker DJ, Jaklitsch MT. Repeated and aggressive pulmonary resections for leiomyosarcoma metastases extends survival. Ann Thorac Surg. 2011 Oct; 92(4):1202-7. PMID: 21867989.
    Citations: 12     Fields:    Translation:Humans
  87. Nelson HH, Almquist LM, LaRocca JL, Plaza SL, Lambert-Messerlian GM, Sugarbaker DJ, Bueno R, Godleski JJ, Marsit CJ, Christensen BC, Kelsey KT. The relationship between tumor MSLN methylation and serum mesothelin (SMRP) in mesothelioma. Epigenetics. 2011 Aug; 6(8):1029-34. PMID: 21775819.
    Citations: 3     Fields:    Translation:HumansCells
  88. Gordon GJ, Bueno R, Sugarbaker DJ. Genes associated with prognosis after surgery for malignant pleural mesothelioma promote tumor cell survival in vitro. BMC Cancer. 2011 May 13; 11:169. PMID: 21569526.
    Citations: 7     Fields:    Translation:HumansCells
  89. Burt BM, Rodig SJ, Tilleman TR, Elbardissi AW, Bueno R, Sugarbaker DJ. Circulating and tumor-infiltrating myeloid cells predict survival in human pleural mesothelioma. Cancer. 2011 Nov 15; 117(22):5234-44. PMID: 21523763.
    Citations: 24     Fields:    Translation:HumansCells
  90. Sugarbaker DJ, Wolf AS, Chirieac LR, Godleski JJ, Tilleman TR, Jaklitsch MT, Bueno R, Richards WG. Clinical and pathological features of three-year survivors of malignant pleural mesothelioma following extrapleural pneumonectomy. Eur J Cardiothorac Surg. 2011 Aug; 40(2):298-303. PMID: 21310625.
    Citations: 16     Fields:    Translation:Humans
  91. Cooley ME, Emmons KM, Haddad R, Wang Q, Posner M, Bueno R, Cohen TJ, Johnson BE. Patient-reported receipt of and interest in smoking-cessation interventions after a diagnosis of cancer. Cancer. 2011 Jul 01; 117(13):2961-9. PMID: 21692055.
    Citations: 17     Fields:    Translation:Humans
  92. Ou WB, Hubert C, Corson JM, Bueno R, Flynn DL, Sugarbaker DJ, Fletcher JA. Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma. Neoplasia. 2011 Jan; 13(1):12-22. PMID: 21245936.
    Citations: 22     Fields:    Translation:HumansCells
  93. Ou WB, Corson JM, Flynn DL, Lu WP, Wise SC, Bueno R, Sugarbaker DJ, Fletcher JA. AXL regulates mesothelioma proliferation and invasiveness. Oncogene. 2011 Apr 07; 30(14):1643-52. PMID: 21132014.
    Citations: 26     Fields:    Translation:HumansCells
  94. De Rienzo A, Dong L, Yeap BY, Jensen RV, Richards WG, Gordon GJ, Sugarbaker DJ, Bueno R. Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma. Clin Cancer Res. 2011 Jan 15; 17(2):310-6. PMID: 21088255.
    Citations: 9     Fields:    Translation:HumansCells
  95. Wolf AS, Richards WG, Tilleman TR, Chirieac L, Hurwitz S, Bueno R, Sugarbaker DJ. Characteristics of malignant pleural mesothelioma in women. Ann Thorac Surg. 2010 Sep; 90(3):949-56; discussion 956. PMID: 20732523.
    Citations: 9     Fields:    Translation:Humans
  96. Koestler DC, Marsit CJ, Christensen BC, Karagas MR, Bueno R, Sugarbaker DJ, Kelsey KT, Houseman EA. Semi-supervised recursively partitioned mixture models for identifying cancer subtypes. Bioinformatics. 2010 Oct 15; 26(20):2578-85. PMID: 20834038.
    Citations: 25     Fields:    Translation:Humans
  97. Mujoomdar AA, Tilleman TR, Richards WG, Bueno R, Sugarbaker DJ. Prevalence of in vitro chemotherapeutic drug resistance in primary malignant pleural mesothelioma: result in a cohort of 203 resection specimens. J Thorac Cardiovasc Surg. 2010 Aug; 140(2):352-5. PMID: 20653100.
    Citations: 7     Fields:    Translation:HumansCells
  98. Christensen BC, Houseman EA, Poage GM, Godleski JJ, Bueno R, Sugarbaker DJ, Wiencke JK, Nelson HH, Marsit CJ, Kelsey KT. Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma. Cancer Res. 2010 Jul 15; 70(14):5686-94. PMID: 20587528.
    Citations: 14     Fields:    Translation:HumansCells
  99. Bueno R, De Rienzo A, Dong L, Gordon GJ, Hercus CF, Richards WG, Jensen RV, Anwar A, Maulik G, Chirieac LR, Ho KF, Taillon BE, Turcotte CL, Hercus RG, Gullans SR, Sugarbaker DJ. Second generation sequencing of the mesothelioma tumor genome. PLoS One. 2010 May 13; 5(5):e10612. PMID: 20485525.
    Citations: 26     Fields:    Translation:HumansCells
  100. Richards WG, Godleski JJ, Yeap BY, Corson JM, Chirieac LR, Zellos L, Mujoomdar A, Jaklitsch MT, Bueno R, Sugarbaker DJ. Proposed adjustments to pathologic staging of epithelial malignant pleural mesothelioma based on analysis of 354 cases. Cancer. 2010 Mar 15; 116(6):1510-7. PMID: 20108310.
    Citations: 15     Fields:    Translation:Humans
  101. Bueno R. New technique for Heller myotomy with the LigaSure device alone. Semin Thorac Cardiovasc Surg. 2010; 22(2):187-8. PMID: 21092899.
    Citations:    Fields:    Translation:Humans
  102. Dong L, Jensen RV, De Rienzo A, Gordon GJ, Xu Y, Sugarbaker DJ, Bueno R. Differentially expressed alternatively spliced genes in malignant pleural mesothelioma identified using massively parallel transcriptome sequencing. BMC Med Genet. 2009 Dec 31; 10:149. PMID: 20043850.
    Citations: 5     Fields:    Translation:HumansCells
  103. DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK. Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet. 2009 Oct; 85(4):493-502. PMID: 19800047.
    Citations: 54     Fields:    Translation:HumansCells
  104. Caglar HB, Baldini EH, Othus M, Rabin MS, Bueno R, Sugarbaker DJ, Mentzer SJ, Jänne PA, Johnson BE, Allen AM. Outcomes of patients with stage III nonsmall cell lung cancer treated with chemotherapy and radiation with and without surgery. Cancer. 2009 Sep 15; 115(18):4156-66. PMID: 19551884.
    Citations: 11     Fields:    Translation:Humans
  105. Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet. 2009 Aug; 5(8):e1000602. PMID: 19680444.
    Citations: 335     Fields:    Translation:HumansCellsPHPublic Health
  106. Tilleman TR, Richards WG, Zellos L, Johnson BE, Jaklitsch MT, Mueller J, Yeap BY, Mujoomdar AA, Ducko CT, Bueno R, Sugarbaker DJ. Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):405-11. PMID: 19619785.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  107. Christensen BC, Marsit CJ, Houseman EA, Godleski JJ, Longacker JL, Zheng S, Yeh RF, Wrensch MR, Wiemels JL, Karagas MR, Bueno R, Sugarbaker DJ, Nelson HH, Wiencke JK, Kelsey KT. Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles. Cancer Res. 2009 Aug 01; 69(15):6315-21. PMID: 19638575.
    Citations: 22     Fields:    Translation:HumansCells
  108. Sugarbaker DJ, Tilleman TR, Swanson SJ, Jaklitsch MT, Mentzer SJ, Mujoomdar AA, Bueno R. The role of extrapleural pneumonectomy in the management of pleural cancers. J Clin Oncol. 2009 May 20; 27(15_suppl):7577. PMID: 27963385.
    Citations:    
  109. Paul S, Escareno CE, Clancy K, Jaklitsch MT, Bueno R, Lautz DB. Gastrointestinal complications after lung transplantation. J Heart Lung Transplant. 2009 May; 28(5):475-9. PMID: 19416776.
    Citations: 9     Fields:    Translation:Humans
  110. Gordon GJ, Dong L, Yeap BY, Richards WG, Glickman JN, Edenfield H, Mani M, Colquitt R, Maulik G, Van Oss B, Sugarbaker DJ, Bueno R. Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma. J Natl Cancer Inst. 2009 May 06; 101(9):678-86. PMID: 19401544.
    Citations: 22     Fields:    Translation:Humans
  111. Cooley ME, Sarna L, Kotlerman J, Lukanich JM, Jaklitsch M, Green SB, Bueno R. Smoking cessation is challenging even for patients recovering from lung cancer surgery with curative intent. Lung Cancer. 2009 Nov; 66(2):218-25. PMID: 19321223.
    Citations: 33     Fields:    Translation:Humans
  112. Zellos L, Richards WG, Capalbo L, Jaklitsch MT, Chirieac LR, Johnson BE, Bueno R, Sugarbaker DJ. A phase I study of extrapleural pneumonectomy and intracavitary intraoperative hyperthermic cisplatin with amifostine cytoprotection for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2009 Feb; 137(2):453-8. PMID: 19185169.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  113. Dong L, Bard AJ, Richards WG, Nitz MD, Theodorescu D, Bueno R, Gordon GJ. A gene expression ratio-based diagnostic test for bladder cancer. Adv Appl Bioinform Chem. 2009; 2:17-22. PMID: 21918612.
    Citations: 6     
  114. Bueno R. Making the case for molecular staging of malignant pleural mesothelioma. Semin Thorac Cardiovasc Surg. 2009; 21(2):188-93. PMID: 19822292.
    Citations: 1     Fields:    Translation:Humans
  115. Christensen BC, Houseman EA, Godleski JJ, Marsit CJ, Longacker JL, Roelofs CR, Karagas MR, Wrensch MR, Yeh RF, Nelson HH, Wiemels JL, Zheng S, Wiencke JK, Bueno R, Sugarbaker DJ, Kelsey KT. Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res. 2009 Jan 01; 69(1):227-34. PMID: 19118007.
    Citations: 45     Fields:    Translation:HumansCells
  116. Miller NA, Kingsmore SF, Farmer A, Langley RJ, Mudge J, Crow JA, Gonzalez AJ, Schilkey FD, Kim RJ, van Velkinburgh J, May GD, Black CF, Myers MK, Utsey JP, Frost NS, Sugarbaker DJ, Bueno R, Gullans SR, Baxter SM, Day SW, Retzel EF. Management of High-Throughput DNA Sequencing Projects: Alpheus. J Comput Sci Syst Biol. 2008 Dec 26; 1:132. PMID: 20151039.
    Citations: 34     
  117. Garcia A, Byrne JG, Bueno R, Flores RM. Aneurysm of the main pulmonary artery. Ann Thorac Cardiovasc Surg. 2008 Dec; 14(6):399-401. PMID: 19131930.
    Citations: 2     Fields:    Translation:Humans
  118. Bhattacharya S, Srisuma S, Demeo DL, Shapiro SD, Bueno R, Silverman EK, Reilly JJ, Mariani TJ. Molecular biomarkers for quantitative and discrete COPD phenotypes. Am J Respir Cell Mol Biol. 2009 Mar; 40(3):359-67. PMID: 18849563.
    Citations: 44     Fields:    Translation:Humans
  119. Paul S, Su S, Edenfield H, Kwiatkowski DJ, Bueno R. Treatment of refractory lymphangioleiomyomatosis-associated chylous effusion with a pleuroperitoneal window and omental flap. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):497-8. PMID: 19619804.
    Citations:    Fields:    Translation:Humans
  120. Christensen BC, Godleski JJ, Roelofs CR, Longacker JL, Bueno R, Sugarbaker DJ, Marsit CJ, Nelson HH, Kelsey KT. Asbestos burden predicts survival in pleural mesothelioma. Environ Health Perspect. 2008 Jun; 116(6):723-6. PMID: 18560526.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  121. Wilson SM, Barbone D, Yang TM, Jablons DM, Bueno R, Sugarbaker DJ, Nishimura SL, Gordon GJ, Broaddus VC. mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids. Am J Respir Cell Mol Biol. 2008 Nov; 39(5):576-83. PMID: 18511708.
    Citations: 23     Fields:    Translation:HumansCells
  122. Allen AM, Mentzer SJ, Yeap BY, Soto R, Baldini EH, Rabin MS, Sugarbaker DJ, Bueno R. Pneumonectomy after chemoradiation: the Dana-Farber Cancer Institute/Brigham and Women's Hospital experience. Cancer. 2008 Mar 01; 112(5):1106-13. PMID: 18286507.
    Citations: 8     Fields:    Translation:Humans
  123. Christensen BC, Godleski JJ, Marsit CJ, Houseman EA, Lopez-Fagundo CY, Longacker JL, Bueno R, Sugarbaker DJ, Nelson HH, Kelsey KT. Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma. Carcinogenesis. 2008 Aug; 29(8):1555-9. PMID: 18310086.
    Citations: 24     Fields:    Translation:HumansCellsPHPublic Health
  124. Sugarbaker DJ, Richards WG, Gordon GJ, Dong L, De Rienzo A, Maulik G, Glickman JN, Chirieac LR, Hartman ML, Taillon BE, Du L, Bouffard P, Kingsmore SF, Miller NA, Farmer AD, Jensen RV, Gullans SR, Bueno R. Transcriptome sequencing of malignant pleural mesothelioma tumors. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3521-6. PMID: 18303113.
    Citations: 63     Fields:    Translation:HumansCells
  125. Feller-Kopman D, Lukanich JM, Shapira G, Kolodny U, Schori B, Edenfield H, Temelkuran B, Ernst A, Schindel Y, Fink Y, Fox J, Bueno R. Gas flow during bronchoscopic ablation therapy causes gas emboli to the heart: a comparative animal study. Chest. 2008 Apr; 133(4):892-6. PMID: 18198247.
    Citations: 4     Fields:    Translation:Animals
  126. Neragi-Miandoab S, Linden PA, Ducko CT, Bueno R, Richards WG, Sugarbaker DJ, Jaklitsch MT. VATS pericardiotomy for patients with known malignancy and pericardial effusion: survival and prognosis of positive cytology and metastatic involvement of the pericardium: a case control study. Int J Surg. 2008 Apr; 6(2):110-4. PMID: 18329349.
    Citations: 3     Fields:    Translation:Humans
  127. Jagadeeswaran R, Surawska H, Krishnaswamy S, Janamanchi V, Mackinnon AC, Seiwert TY, Loganathan S, Kanteti R, Reichman T, Nallasura V, Schwartz S, Faoro L, Wang YC, Girard L, Tretiakova MS, Ahmed S, Zumba O, Soulii L, Bindokas VP, Szeto LL, Gordon GJ, Bueno R, Sugarbaker D, Lingen MW, Sattler M, Krausz T, Vigneswaran W, Natarajan V, Minna J, Vokes EE, Ferguson MK, Husain AN, Salgia R. Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Cancer Res. 2008 Jan 01; 68(1):132-42. PMID: 18172305.
    Citations: 53     Fields:    Translation:HumansAnimals
  128. Allen AM, Den R, Wong JS, Zurakowski D, Soto R, Jänne PA, Zellos L, Bueno R, Sugarbaker DJ, Baldini EH. Influence of radiotherapy technique and dose on patterns of failure for mesothelioma patients after extrapleural pneumonectomy. Int J Radiat Oncol Biol Phys. 2007 Aug 01; 68(5):1366-74. PMID: 17674974.
    Citations: 10     Fields:    Translation:Humans
  129. Richards WG, Van Oss SB, Glickman JN, Chirieac LR, Yeap B, Dong L, Gordon GJ, Mercer H, Gill KK, Imrich A, Bueno R, Sugarbaker DJ. A microaliquoting technique for precise histological annotation and optimization of cell content in frozen tissue specimens. Biotech Histochem. 2007 Aug; 82(4-5):189-97. PMID: 17917854.
    Citations: 7     Fields:    Translation:Humans
  130. Paul S, Jain SH, Gallegos RP, Aranki SF, Bueno R. Functional paraganglioma of the middle mediastinum. Ann Thorac Surg. 2007 Jun; 83(6):e14-6. PMID: 17532372.
    Citations: 6     Fields:    Translation:Humans
  131. Gordon GJ, Mani M, Maulik G, Mukhopadhyay L, Yeap BY, Kindler HL, Salgia R, Sugarbaker DJ, Bueno R. Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma. Cancer Chemother Pharmacol. 2008 Apr; 61(4):549-58. PMID: 17522864.
    Citations: 17     Fields:    Translation:HumansCells
  132. Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Yeap BY, Sugarbaker DJ, Bueno R. Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma. J Pathol. 2007 Mar; 211(4):439-46. PMID: 17253597.
    Citations: 22     Fields:    Translation:HumansCells
  133. Silletti JP, Gordon GJ, Bueno R, Jaklitsch M, Loughlin KR. Prostate biopsy: past, present, and future. Urology. 2007 Mar; 69(3):413-6. PMID: 17382133.
    Citations: 6     Fields:    Translation:Humans
  134. Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Edenfield HR, Glickman JN, Yeap BY, Sugarbaker DJ, Bueno R. Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma. J Pathol. 2007 Mar; 211(4):447-54. PMID: 17253596.
    Citations: 18     Fields:    Translation:HumansCells
  135. Linden PA, Bueno R, Mentzer SJ, Zellos L, Lebenthal A, Colson YL, Sugarbaker DJ, Jaklitsch MT. Modified T-tube repair of delayed esophageal perforation results in a low mortality rate similar to that seen with acute perforations. Ann Thorac Surg. 2007 Mar; 83(3):1129-33. PMID: 17307472.
    Citations: 15     Fields:    Translation:Humans
  136. Linden PA, Yeap BY, Chang MY, Henderson WG, Jaklitsch MT, Khuri S, Sugarbaker DJ, Bueno R. Morbidity of lung resection after prior lobectomy: results from the Veterans Affairs National Surgical Quality Improvement Program. Ann Thorac Surg. 2007 Feb; 83(2):425-31; discussion 432. PMID: 17257965.
    Citations: 2     Fields:    Translation:Humans
  137. Stewart AJ, O'Farrell DA, Mutyala S, Bueno R, Sugarbaker DJ, Cormack RA, Devlin PM. Severe toxicity after permanent radioactive seed implantation for mediastinal carcinoid tumors. Brachytherapy. 2007 Jan-Mar; 6(1):58-61. PMID: 17284388.
    Citations:    Fields:    Translation:Humans
  138. Marsit CJ, Houseman EA, Christensen BC, Eddy K, Bueno R, Sugarbaker DJ, Nelson HH, Karagas MR, Kelsey KT. Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res. 2006 Nov 01; 66(21):10621-9. PMID: 17079487.
    Citations: 30     Fields:    Translation:HumansCells
  139. Gordon GJ, Deters LA, Nitz MD, Lieberman BC, Yeap BY, Bueno R. Differential diagnosis of solitary lung nodules with gene expression ratios. J Thorac Cardiovasc Surg. 2006 Sep; 132(3):621-7. PMID: 16935118.
    Citations: 4     Fields:    Translation:Humans
  140. Fong DG, Bueno R, Thompson CC. Esophageal mucocele presenting as a draining fistula after colonic interposition. Gastrointest Endosc. 2006 Aug; 64(2):290-1. PMID: 16860092.
    Citations: 1     Fields:    Translation:Humans
  141. Bhattacharya S, Srisuma S, Demeo DL, Reilly JJ, Bueno R, Silverman EK, Mariani TJ. Microarray data-based prioritization of chronic obstructive pulmonary disease susceptibility genes. Proc Am Thorac Soc. 2006 Aug; 3(6):472. PMID: 16921109.
    Citations: 4     Fields:    Translation:Humans
  142. Allen AM, Czerminska M, Jänne PA, Sugarbaker DJ, Bueno R, Harris JR, Court L, Baldini EH. Fatal pneumonitis associated with intensity-modulated radiation therapy for mesothelioma. Int J Radiat Oncol Biol Phys. 2006 Jul 01; 65(3):640-5. PMID: 16751058.
    Citations: 80     Fields:    Translation:Humans
  143. Ettinger DS, Bepler G, Bueno R, Chang A, Chang JY, Chirieac LR, D'Amico TA, Demmy TL, Feigenberg SJ, Grannis FW, Jahan T, Jahanzeb M, Kessinger A, Komaki R, Kris MG, Langer CJ, Le QT, Martins R, Otterson GA, Robert F, Sugarbaker DJ, Wood DE. Non-small cell lung cancer clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2006 Jul; 4(6):548-82. PMID: 16813724.
    Citations: 41     Fields:    Translation:Humans
  144. Allen AM, Den R, Wong JS, Janne PA, Zurakowski D, Soto R, Bueno R, Sugarbaker DJ, Baldini EH. The influence of radiotherapy technique and dose on the patterns of failure for mesothelioma patients following extrapleural pneumonectomy. J Clin Oncol. 2006 Jun 20; 24(18_suppl):7094. PMID: 27953361.
    Citations:    
  145. Richards WG, Zellos L, Bueno R, Jaklitsch MT, Jänne PA, Chirieac LR, Yeap BY, Dekkers RJ, Hartigan PM, Capalbo L, Sugarbaker DJ. Phase I to II study of pleurectomy/decortication and intraoperative intracavitary hyperthermic cisplatin lavage for mesothelioma. J Clin Oncol. 2006 Apr 01; 24(10):1561-7. PMID: 16575008.
    Citations: 40     Fields:    Translation:HumansCTClinical Trials
  146. Mukhopadhyay NK, Weisberg E, Gilchrist D, Bueno R, Sugarbaker DJ, Jaklitsch MT. Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. Ann Thorac Surg. 2006 Mar; 81(3):1034-42. PMID: 16488717.
    Citations: 14     Fields:    Translation:HumansCells
  147. Linden PA, Gilbert RJ, Yeap BY, Boyle K, Deykin A, Jaklitsch MT, Sugarbaker DJ, Bueno R. Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation. J Thorac Cardiovasc Surg. 2006 Feb; 131(2):438-46. PMID: 16434276.
    Citations: 42     Fields:    Translation:Humans
  148. Jagadeeswaran R, Ma PC, Seiwert TY, Jagadeeswaran S, Zumba O, Nallasura V, Ahmed S, Filiberti R, Paganuzzi M, Puntoni R, Kratzke RA, Gordon GJ, Sugarbaker DJ, Bueno R, Janamanchi V, Bindokas VP, Kindler HL, Salgia R. Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma. Cancer Res. 2006 Jan 01; 66(1):352-61. PMID: 16397249.
    Citations: 58     Fields:    Translation:HumansCells
  149. Bueno R. Multimodality treatments in the management of malignant pleural mesothelioma: an update. Hematol Oncol Clin North Am. 2005 Dec; 19(6):1089-97, vii. PMID: 16325125.
    Citations: 4     Fields:    Translation:Humans
  150. Chen RH, Lautz D, Gilbert RJ, Bueno R. Antireflux operation for gastroesophageal reflux after Roux-en-y gastric bypass for obesity. Ann Thorac Surg. 2005 Nov; 80(5):1938-40. PMID: 16242496.
    Citations: 2     Fields:    Translation:Humans
  151. Mery CM, Pappas AN, Burt BM, Bueno R, Linden PA, Sugarbaker DJ, Jaklitsch MT. Diameter of non-small cell lung cancer correlates with long-term survival: implications for T stage. Chest. 2005 Nov; 128(5):3255-60. PMID: 16304270.
    Citations: 9     Fields:    Translation:Humans
  152. Mukhopadhyay NK, Gordon GJ, Maulik G, Doerre G, Liu BC, Bueno R, Sugarbaker DJ, Jaklitsch MT. Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast. J Cell Mol Med. 2005 Jul-Sep; 9(3):662-9. PMID: 16202213.
    Citations: 3     Fields:    Translation:HumansCells
  153. Mery CM, Pappas AN, Bueno R, Colson YL, Linden P, Sugarbaker DJ, Jaklitsch MT. Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the surveillance, epidemiology, and end results database. Chest. 2005 Jul; 128(1):237-45. PMID: 16002941.
    Citations: 68     Fields:    Translation:Humans
  154. Gordon GJ, Rockwell GN, Godfrey PA, Jensen RV, Glickman JN, Yeap BY, Richards WG, Sugarbaker DJ, Bueno R. Validation of genomics-based prognostic tests in malignant pleural mesothelioma. Clin Cancer Res. 2005 Jun 15; 11(12):4406-14. PMID: 15958625.
    Citations: 18     Fields:    Translation:Humans
  155. Linden PA, Bueno R, Colson YL, Jaklitsch MT, Lukanich J, Mentzer S, Sugarbaker DJ. Lung resection in patients with preoperative FEV1 < 35% predicted. Chest. 2005 Jun; 127(6):1984-90. PMID: 15951309.
    Citations: 18     Fields:    Translation:Humans
  156. Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R. Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling. Am J Pathol. 2005 Jun; 166(6):1827-40. PMID: 15920167.
    Citations: 58     Fields:    Translation:HumansCells
  157. Mukhopadhyay NK, Gordon GJ, Chen CJ, Bueno R, Sugarbaker DJ, Jaklitsch MT. Activation of focal adhesion kinase in human lung cancer cells involves multiple and potentially parallel signaling events. J Cell Mol Med. 2005 Apr-Jun; 9(2):387-97. PMID: 15963258.
    Citations: 13     Fields:    Translation:HumansCells
  158. Mamon HJ, Yeap BY, Jänne PA, Reblando J, Shrager S, Jaklitsch MT, Mentzer S, Lukanich JM, Sugarbaker DJ, Baldini EH, Berman S, Skarin A, Bueno R. High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation. J Clin Oncol. 2005 Mar 01; 23(7):1530-7. PMID: 15735128.
    Citations: 38     Fields:    Translation:Humans