Harvard Catalyst Profiles

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Hanno Steen, Ph.D.

Title
Institution
Department
Address
Phone

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01DK108327 (CONWELL, DARWIN LEWIS) Sep 28, 2015 - Aug 31, 2020
    NIH/NIDDK
    The Ohio State University Pancreatic Disorders Network (OSU-PDN)
    Role: Co-Principal Investigator
  2. S10OD010706 (STEEN, HANNO) May 1, 2012 - Apr 30, 2013
    NIH
    TripleTOF 5600 Hybrid Mass Spectrometer
    Role: Principal Investigator
  3. R01GM094844 (STEEN, HANNO) Sep 1, 2010 - Aug 31, 2014
    NIH/NIGMS
    Defining the true nature of the minimal cell cycle with quantitative proteomics
    Role: Principal Investigator
  4. P30DK034854 (LENCER, WAYNE I) Sep 30, 1984 - Nov 30, 2020
    NIH/NIDDK
    Integrated Epithelial and Mucosal Biology
    Role: Co-Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Proteomics Center at Boston Children's Hospital - Core services (11) and Instruments (3)
Molecular and Cellular Biochemistry Core (BCH) - Core services (12) and Instruments (5)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kirov S, Sasson A, Zhang C, Chasalow S, Dongre A, Steen H, Stensballe A, Andersen V, Birkelund S, Bennike TB. Degradation of the extracellular matrix is part of the pathology of ulcerative colitis. Mol Omics. 2019 Feb 11; 15(1):67-76. PMID: 30702115.
    Citations:    
  2. Fisher WE, Cruz-Monserrate Z, McElhany AL, Lesinski GB, Hart PA, Ghosh R, Van Buren G, Fishman DS, Rinaudo JAS, Serrano J, Srivastava S, Mace T, Topazian M, Feng Z, Yadav D, Pandol SJ, Hughes SJ, Liu RY, Lu E, Orr R, Whitcomb DC, Abouhamze AS, Steen H, Sellers ZM, Troendle DM, Uc A, Lowe ME, Conwell DL. Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1213-1221. PMID: 30325860.
    Citations:    Fields:    
  3. Bennike TB, Bellin MD, Xuan Y, Stensballe A, Møller FT, Beilman GJ, Levy O, Cruz-Monserrate Z, Andersen V, Steen J, Conwell DL, Steen H. A Cost-Effective High-Throughput Plasma and Serum Proteomics Workflow Enables Mapping of the Molecular Impact of Total Pancreatectomy with Islet Autotransplantation. J Proteome Res. 2018 May 04; 17(5):1983-1992. PMID: 29641209.
    Citations:    Fields:    
  4. Carette X, Platig J, Young DC, Helmel M, Young AT, Wang Z, Potluri LP, Moody CS, Zeng J, Prisic S, Paulson JN, Muntel J, Madduri AVR, Velarde J, Mayfield JA, Locher C, Wang T, Quackenbush J, Rhee KY, Moody DB, Steen H, Husson RN. Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface. MBio. 2018 03 06; 9(2). PMID: 29511081.
    Citations:    Fields:    Translation:Cells
  5. Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, Emde AK, Shah M, Arora K, Reeves C, Socci ND, Perlman E, Antonescu CR, Roberts CWM, Steen H, Mullen E, Jackson SP, Torrents D, Weng Z, Armstrong SA, Kentsis A. Erratum: PGBD5 promotes site-specific oncogenic mutations in human tumors. Nat Genet. 2017 09 27; 49(10):1558. PMID: 28951624.
    Citations:    Fields:    
  6. Davis-Anderson KL, Berger S, Lunde-Young ER, Naik VD, Seo H, Johnson GA, Steen H, Ramadoss J. Placental Proteomics Reveal Insights into Fetal Alcohol Spectrum Disorders. Alcohol Clin Exp Res. 2017 Sep; 41(9):1551-1558. PMID: 28722160.
    Citations:    Fields:    Translation:Animals
  7. Meyer JG, Mukkamalla S, Steen H, Nesvizhskii AI, Gibson BW, Schilling B. PIQED: automated identification and quantification of protein modifications from DIA-MS data. Nat Methods. 2017 Jun 29; 14(7):646-647. PMID: 28661500.
    Citations: 3     Fields:    
  8. Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, Emde AK, Shah M, Arora K, Reeves C, Socci ND, Perlman E, Antonescu CR, Roberts CWM, Steen H, Mullen E, Jackson SP, Torrents D, Weng Z, Armstrong SA, Kentsis A. PGBD5 promotes site-specific oncogenic mutations in human tumors. Nat Genet. 2017 Jul; 49(7):1005-1014. PMID: 28504702.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Bennike TB, Steen H. High-Throughput Parallel Proteomic Sample Preparation Using 96-Well Polyvinylidene Fluoride (PVDF) Membranes and C18 Purification Plates. Methods Mol Biol. 2017; 1619:395-402. PMID: 28674899.
    Citations: 1     Fields:    Translation:Humans
  10. Hart PA, Topazian M, Raimondo M, Cruz-Monserrate Z, Fisher WE, Lesinski GB, Steen H, Conwell DL. Endoscopic Pancreas Fluid Collection: Methods and Relevance for Clinical Care and Translational Science. Am J Gastroenterol. 2016 09; 111(9):1258-66. PMID: 27481304.
    Citations: 6     Fields:    Translation:HumansCells
  11. Froehlich JW, Kostel SA, Cho PS, Briscoe AC, Steen H, Vaezzadeh AR, Lee RS. Urinary Proteomics Yield Pathological Insights for Ureteropelvic Junction Obstruction. Mol Cell Proteomics. 2016 08; 15(8):2607-15. PMID: 27215552; PMCID: PMC4974339.
    Citations:    Fields:    Translation:Humans
  12. Chatterjee B, Makarov A, Clemmer DE, Steen H, Steen J, Saffell-Clemmer W, Moghekar AR, Mohan Rao C, Bradshaw RA, Thakur SS. Proteomics in India: A Report on a Brainstorming Meeting at Hyderabad, India. Mol Cell Proteomics. 2016 07; 15(7):2229-35. PMID: 27114450; PMCID: PMC4937500.
    Citations:    Fields:    
  13. Tang S, Hemberg M, Cansizoglu E, Belin S, Kosik K, Kreiman G, Steen H, Steen J. f-divergence cutoff index to simultaneously identify differential expression in the integrated transcriptome and proteome. Nucleic Acids Res. 2016 06 02; 44(10):e97. PMID: 26980280; PMCID: PMC4889934.
    Citations:    Fields:    
  14. Mair W, Muntel J, Tepper K, Tang S, Biernat J, Seeley WW, Kosik KS, Mandelkow E, Steen H, Steen JA. FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease. Anal Chem. 2016 Apr 05; 88(7):3704-14. PMID: 26877193.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  15. Oh DY, Dowling DJ, Ahmed S, Choi H, Brightman S, Bergelson I, Berger ST, Sauld JF, Pettengill M, Kho AT, Pollack HJ, Steen H, Levy O. Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures. Mol Cell Proteomics. 2016 06; 15(6):1877-94. PMID: 26933193.
    Citations: 3     Fields:    Translation:HumansCells
  16. Chau KF, Springel MW, Broadbelt KG, Park HY, Topal S, Lun MP, Mullan H, Maynard T, Steen H, LaMantia AS, Lehtinen MK. Progressive Differentiation and Instructive Capacities of Amniotic Fluid and Cerebrospinal Fluid Proteomes following Neural Tube Closure. Dev Cell. 2015 Dec 21; 35(6):789-802. PMID: 26702835.
    Citations: 10     Fields:    Translation:AnimalsCells
  17. Muntel J, Xuan Y, Berger ST, Reiter L, Bachur R, Kentsis A, Steen H. Advancing Urinary Protein Biomarker Discovery by Data-Independent Acquisition on a Quadrupole-Orbitrap Mass Spectrometer. J Proteome Res. 2015 Nov 06; 14(11):4752-62. PMID: 26423119; PMCID: PMC4993212.
    Citations: 13     Fields:    Translation:HumansCells
  18. Bennike TB, Barnaby O, Steen H, Stensballe A. Characterization of the porcine synovial fluid proteome and a comparison to the plasma proteome. Data Brief. 2015 Dec; 5:241-7. PMID: 26543887; PMCID: PMC4589796.
    Citations:    
  19. Berger ST, Ahmed S, Muntel J, Cuevas Polo N, Bachur R, Kentsis A, Steen J, Steen H. MStern Blotting-High Throughput Polyvinylidene Fluoride (PVDF) Membrane-Based Proteomic Sample Preparation for 96-Well Plates. Mol Cell Proteomics. 2015 Oct; 14(10):2814-23. PMID: 26223766; PMCID: PMC4597154.
    Citations: 6     Fields:    Translation:HumansCells
  20. Dhabaria A, Cifani P, Reed C, Steen H, Kentsis A. A High-Efficiency Cellular Extraction System for Biological Proteomics. J Proteome Res. 2015 Aug 07; 14(8):3403-8. PMID: 26153614; PMCID: PMC4529808.
    Citations: 3     Fields:    Translation:HumansCells
  21. Prisic S, Hwang H, Dow A, Barnaby O, Pan TS, Lonzanida JA, Chazin WJ, Steen H, Husson RN. Zinc regulates a switch between primary and alternative S18 ribosomal proteins in Mycobacterium tuberculosis. Mol Microbiol. 2015 Jul; 97(2):263-80. PMID: 25858183; PMCID: PMC4548965.
    Citations: 9     Fields:    Translation:Cells
  22. Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK. Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25; 35(12):4903-16. PMID: 25810521; PMCID: PMC4389594.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  23. Laurent B, Ruitu L, Murn J, Hempel K, Ferrao R, Xiang Y, Liu S, Garcia BA, Wu H, Wu F, Steen H, Shi Y. A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation. Mol Cell. 2015 Mar 19; 57(6):957-970. PMID: 25684206.
    Citations: 47     Fields:    Translation:HumansCells
  24. Abu Dayyeh BK, Conwell D, Buttar NS, Kadilaya V, Hart PA, Baumann NA, Bick BL, Chari ST, Chowdhary S, Clain JE, Gleeson FC, Lee LS, Levy MJ, Pearson RK, Petersen BT, Rajan E, Steen H, Suleiman S, Banks PA, Vege SS, Topazian M. Pancreatic juice prostaglandin e2 concentrations are elevated in chronic pancreatitis and improve detection of early disease. Clin Transl Gastroenterol. 2015 Jan 29; 6:e72. PMID: 25630864; PMCID: PMC4418410.
    Citations: 1     
  25. Winter D, Dehghani A, Steen H. Optimization of cell lysis and protein digestion protocols for protein analysis by LC-MS/MS. Methods Mol Biol. 2015; 1295:259-73. PMID: 25820728.
    Citations: 1     Fields:    Translation:Cells
  26. Muntel J, Boswell SA, Tang S, Ahmed S, Wapinski I, Foley G, Steen H, Springer M. Abundance-based classifier for the prediction of mass spectrometric peptide detectability upon enrichment (PPA). Mol Cell Proteomics. 2015 Feb; 14(2):430-40. PMID: 25473088; PMCID: PMC4350037.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  27. Prabakaran S, Hemberg M, Chauhan R, Winter D, Tweedie-Cullen RY, Dittrich C, Hong E, Gunawardena J, Steen H, Kreiman G, Steen JA. Quantitative profiling of peptides from RNAs classified as noncoding. Nat Commun. 2014 Nov 18; 5:5429. PMID: 25403355; PMCID: PMC4416701.
    Citations: 11     Fields:    Translation:AnimalsCells
  28. Gallardo G, Barowski J, Ravits J, Siddique T, Lingrel JB, Robertson J, Steen H, Bonni A. An a2-Na/K ATPase/a-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration. Nat Neurosci. 2014 Dec; 17(12):1710-9. PMID: 25344630; PMCID: PMC4703324.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  29. Bennike T, Ayturk U, Haslauer CM, Froehlich JW, Proffen BL, Barnaby O, Birkelund S, Murray MM, Warman ML, Stensballe A, Steen H. A normative study of the synovial fluid proteome from healthy porcine knee joints. J Proteome Res. 2014 Oct 03; 13(10):4377-87. PMID: 25160569; PMCID: PMC4184458.
    Citations: 10     Fields:    Translation:AnimalsCells
  30. Singh SA, Winter D, Kirchner M, Chauhan R, Ahmed S, Ozlu N, Tzur A, Steen JA, Steen H. Co-regulation proteomics reveals substrates and mechanisms of APC/C-dependent degradation. EMBO J. 2014 Feb 18; 33(4):385-99. PMID: 24510915; PMCID: PMC3989644.
    Citations: 17     Fields:    Translation:HumansCells
  31. Gutierrez A, Pan L, Groen RW, Baleydier F, Kentsis A, Marineau J, Grebliunaite R, Kozakewich E, Reed C, Pflumio F, Poglio S, Uzan B, Clemons P, VerPlank L, An F, Burbank J, Norton S, Tolliday N, Steen H, Weng AP, Yuan H, Bradner JE, Mitsiades C, Look AT, Aster JC. Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia. J Clin Invest. 2014 Feb; 124(2):644-55. PMID: 24401270; PMCID: PMC3904599.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  32. Mosammaparast N, Kim H, Laurent B, Zhao Y, Lim HJ, Majid MC, Dango S, Luo Y, Hempel K, Sowa ME, Gygi SP, Steen H, Harper JW, Yankner B, Shi Y. The histone demethylase LSD1/KDM1A promotes the DNA damage response. J Cell Biol. 2013 Nov 11; 203(3):457-70. PMID: 24217620; PMCID: PMC3824007.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  33. Serang O, Cansizoglu AE, Käll L, Steen H, Steen JA. Nonparametric Bayesian evaluation of differential protein quantification. J Proteome Res. 2013 Oct 04; 12(10):4556-65. PMID: 24024742; PMCID: PMC3824391.
    Citations: 7     Fields:    Translation:HumansCells
  34. Ikeuchi Y, de la Torre-Ubieta L, Matsuda T, Steen H, Okazawa H, Bonni A. The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons. Cell Rep. 2013 Sep 12; 4(5):879-89. PMID: 23994472; PMCID: PMC4013279.
    Citations: 4     Fields:    Translation:AnimalsCells
  35. McDowell GS, Gaun A, Steen H. iFASP: combining isobaric mass tagging with filter-aided sample preparation. J Proteome Res. 2013 Aug 02; 12(8):3809-12. PMID: 23692318; PMCID: PMC4416645.
    Citations: 9     Fields:    Translation:AnimalsCells
  36. Paulo JA, Kadiyala V, Brizard S, Banks PA, Steen H, Conwell DL. A proteomic comparison of formalin-fixed paraffin-embedded pancreatic tissue from autoimmune pancreatitis, chronic pancreatitis, and pancreatic cancer. JOP. 2013 Jul 10; 14(4):405-14. PMID: 23846938; PMCID: PMC4506757.
    Citations: 4     Fields:    Translation:Humans
  37. Froehlich JW, Vaezzadeh AR, Kirchner M, Briscoe AC, Hofmann O, Hide W, Steen H, Lee RS. An in-depth comparison of the male pediatric and adult urinary proteomes. Biochim Biophys Acta. 2014 May; 1844(5):1044-50. PMID: 23707565; PMCID: PMC3796057.
    Citations: 3     Fields:    Translation:HumansCells
  38. Paulo JA, Urrutia R, Kadiyala V, Banks P, Conwell DL, Steen H. Cross-species analysis of nicotine-induced proteomic alterations in pancreatic cells. Proteomics. 2013 May; 13(9):1499-1512. PMID: 23456891; PMCID: PMC4036444.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  39. Paulo JA, Kadiyala V, Banks PA, Conwell DL, Steen H. Mass spectrometry-based quantitative proteomic profiling of human pancreatic and hepatic stellate cell lines. Genomics Proteomics Bioinformatics. 2013 Apr; 11(2):105-13. PMID: 23528454; PMCID: PMC4123426.
    Citations: 4     Fields:    Translation:HumansCells
  40. Paulo JA, Kadiyala V, Brizard S, Banks PA, Steen H, Conwell DL. Post-translational modifications of pancreatic fluid proteins collected via the endoscopic pancreatic function test (ePFT). J Proteomics. 2013 Oct 30; 92:216-27. PMID: 23500127; PMCID: PMC3731404.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  41. Paulo JA, Kadiyala V, Gaun A, Sauld JF, Ghoulidi A, Banks PA, Steen H, Conwell DL. Analysis of endoscopic pancreatic function test (ePFT)-collected pancreatic fluid proteins precipitated via ultracentrifugation. JOP. 2013 Mar 10; 14(2):176-86. PMID: 23474565; PMCID: PMC4506755.
    Citations:    Fields:    Translation:HumansCells
  42. Berg AH, Drechsler C, Wenger J, Buccafusca R, Hod T, Kalim S, Ramma W, Parikh SM, Steen H, Friedman DJ, Danziger J, Wanner C, Thadhani R, Karumanchi SA. Carbamylation of serum albumin as a risk factor for mortality in patients with kidney failure. Sci Transl Med. 2013 Mar 06; 5(175):175ra29. PMID: 23467560; PMCID: PMC3697767.
    Citations: 30     Fields:    Translation:Humans
  43. Larman HB, Salajegheh M, Nazareno R, Lam T, Sauld J, Steen H, Kong SW, Pinkus JL, Amato AA, Elledge SJ, Greenberg SA. Cytosolic 5'-nucleotidase 1A autoimmunity in sporadic inclusion body myositis. Ann Neurol. 2013 Mar; 73(3):408-18. PMID: 23596012.
    Citations: 37     Fields:    Translation:HumansCells
  44. Pe'er T, Lahmi R, Sharaby Y, Chorni E, Noach M, Vecsler M, Zlotorynski E, Steen H, Steen JA, Tzur A. Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex. PLoS One. 2013; 8(2):e57532. PMID: 23469016; PMCID: PMC3585356.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  45. Serang O, Froehlich JW, Muntel J, McDowell G, Steen H, Lee RS, Steen JA. SweetSEQer, simple de novo filtering and annotation of glycoconjugate mass spectra. Mol Cell Proteomics. 2013 Jun; 12(6):1735-40. PMID: 23443135; PMCID: PMC3675827.
    Citations: 5     Fields:    Translation:Humans
  46. Paulo JA, Gaun A, Kadiyala V, Ghoulidi A, Banks PA, Conwell DL, Steen H. Subcellular fractionation enhances proteome coverage of pancreatic duct cells. Biochim Biophys Acta. 2013 Apr; 1834(4):791-7. PMID: 23352835; PMCID: PMC3618666.
    Citations: 3     Fields:    Translation:Cells
  47. Serang O, Paulo J, Steen H, Steen JA. A non-parametric cutout index for robust evaluation of identified proteins. Mol Cell Proteomics. 2013 Mar; 12(3):807-12. PMID: 23292186; PMCID: PMC3591671.
    Citations: 6     Fields:    Translation:HumansCells
  48. Paulo JA, Kadiyala V, Brizard S, Banks PA, Conwell DL, Steen H. Short Gel, Long Gradient Liquid Chromatography Tandem Mass Spectrometry to Discover Urinary Biomarkers of Chronic Pancreatitis. Open Proteomics J. 2013; 6:1-13. PMID: 25346780.
    Citations: 3     
  49. Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20. PMID: 23281308; PMCID: PMC3569638.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  50. Prabakaran S, Lippens G, Steen H, Gunawardena J. Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding. Wiley Interdiscip Rev Syst Biol Med. 2012 Nov-Dec; 4(6):565-83. PMID: 22899623; PMCID: PMC3473174.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  51. Huang H, Woo AJ, Waldon Z, Schindler Y, Moran TB, Zhu HH, Feng GS, Steen H, Cantor AB. A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation. Genes Dev. 2012 Jul 15; 26(14):1587-601. PMID: 22759635; PMCID: PMC3404386.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  52. Yang W, Kim Y, Kim TK, Keay SK, Kim KP, Steen H, Freeman MR, Hwang D, Kim J. Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled-8 protein-related antiproliferative factor in vivo. BJU Int. 2012 Dec; 110(11 Pt C):E1138-46. PMID: 22738385; PMCID: PMC3461241.
    Citations: 8     Fields:    Translation:HumansCells
  53. Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X. Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Cell. 2012 Jun 22; 149(7):1565-77. PMID: 22726442; PMCID: PMC3383638.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  54. Paulo JA, Kadiyala V, Banks PA, Steen H, Conwell DL. Mass Spectrometry-Based (GeLC-MS/MS) Comparative Proteomic Analysis of Endoscopically (ePFT) Collected Pancreatic and Gastroduodenal Fluids. Clin Transl Gastroenterol. 2012 May 03; 3:e14. PMID: 23238231; PMCID: PMC3367612.
    Citations: 4     
  55. Singh SA, Winter D, Bilimoria PM, Bonni A, Steen H, Steen JA. FLEXIQinase, a mass spectrometry-based assay, to unveil multikinase mechanisms. Nat Methods. 2012 Apr 08; 9(5):504-8. PMID: 22484849; PMCID: PMC3595540.
    Citations: 10     Fields:    Translation:Cells
  56. Renard BY, Xu B, Kirchner M, Zickmann F, Winter D, Korten S, Brattig NW, Tzur A, Hamprecht FA, Steen H. Overcoming species boundaries in peptide identification with Bayesian information criterion-driven error-tolerant peptide search (BICEPS). Mol Cell Proteomics. 2012 Jul; 11(7):M111.014167. PMID: 22493179; PMCID: PMC3394943.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  57. Paulo JA, Kadiyala V, Banks PA, Steen H, Conwell DL. Mass spectrometry-based proteomics for translational research: a technical overview. Yale J Biol Med. 2012 Mar; 85(1):59-73. PMID: 22461744; PMCID: PMC3313540.
    Citations: 6     Fields:    Translation:HumansAnimals
  58. Paulo JA, Lee LS, Banks PA, Steen H, Conwell DL. Proteomic analysis of formalin-fixed paraffin-embedded pancreatic tissue using liquid chromatography tandem mass spectrometry. Pancreas. 2012 Mar; 41(2):175-85. PMID: 22015969; PMCID: PMC3368275.
    Citations: 11     Fields:    Translation:Humans
  59. Paulo JA, Kadiyala V, Lee LS, Banks PA, Conwell DL, Steen H. Proteomic analysis (GeLC-MS/MS) of ePFT-collected pancreatic fluid in chronic pancreatitis. J Proteome Res. 2012 Mar 02; 11(3):1897-912. PMID: 22243521; PMCID: PMC3294251.
    Citations: 14     Fields:    Translation:Humans
  60. Kentsis A, Ahmed S, Kurek K, Brennan E, Bradwin G, Steen H, Bachur R. Detection and diagnostic value of urine leucine-rich a-2-glycoprotein in children with suspected acute appendicitis. Ann Emerg Med. 2012 Jul; 60(1):78-83.e1. PMID: 22305331; PMCID: PMC3726720.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  61. Singh S, Kirchner M, Steen JA, Steen H. A practical guide to the FLEXIQuant method. Methods Mol Biol. 2012; 893:295-319. PMID: 22665308.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  62. Greenberg SA, Salajegheh M, Judge DP, Feldman MW, Kuncl RW, Waldon Z, Steen H, Wagner KR. Etiology of limb girdle muscular dystrophy 1D/1E determined by laser capture microdissection proteomics. Ann Neurol. 2012 Jan; 71(1):141-5. PMID: 22275259.
    Citations: 17     Fields:    Translation:Humans
  63. Winter D, Steen H. Optimization of cell lysis and protein digestion protocols for the analysis of HeLa S3 cells by LC-MS/MS. Proteomics. 2011 Dec; 11(24):4726-30. PMID: 22002805.
    Citations: 8     Fields:    Translation:HumansCells
  64. Anderson DS, Kirchner M, Kellogg M, Kalish LA, Jeong JY, Vanasse G, Berliner N, Fleming MD, Steen H. Design and validation of a high-throughput matrix-assisted laser desorption ionization time-of-flight mass spectrometry method for quantification of hepcidin in human plasma. Anal Chem. 2011 Nov 01; 83(21):8357-62. PMID: 21958231.
    Citations: 3     Fields:    Translation:Humans
  65. Broadbelt KG, Rivera KD, Paterson DS, Duncan JR, Trachtenberg FL, Paulo JA, Stapels MD, Borenstein NS, Belliveau RA, Haas EA, Stanley C, Krous HF, Steen H, Kinney HC. Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndrome. Mol Cell Proteomics. 2012 Jan; 11(1):M111.009530. PMID: 21976671; PMCID: PMC3270099.
    Citations: 14     Fields:    Translation:Humans
  66. Soblik H, Younis AE, Mitreva M, Renard BY, Kirchner M, Geisinger F, Steen H, Brattig NW. Life cycle stage-resolved proteomic analysis of the excretome/secretome from Strongyloides ratti--identification of stage-specific proteases. Mol Cell Proteomics. 2011 Dec; 10(12):M111.010157. PMID: 21964353; PMCID: PMC3237078.
    Citations: 24     Fields:    Translation:AnimalsCells
  67. Wilhelm M, Kirchner M, Steen JA, Steen H. mz5: space- and time-efficient storage of mass spectrometry data sets. Mol Cell Proteomics. 2012 Jan; 11(1):O111.011379. PMID: 21960719; PMCID: PMC3270111.
    Citations: 16     Fields:    Translation:HumansCells
  68. Paulo JA, Urrutia R, Banks PA, Conwell DL, Steen H. Proteomic analysis of a rat pancreatic stellate cell line using liquid chromatography tandem mass spectrometry (LC-MS/MS). J Proteomics. 2011 Dec 21; 75(2):708-17. PMID: 21968429; PMCID: PMC3238025.
    Citations: 16     Fields:    Translation:AnimalsCells
  69. Vanasse GJ, Jeong JY, Tate J, Bathulapalli H, Anderson D, Steen H, Fleming M, Mattocks K, Telenti A, Fellay J, Justice AC, Berliner N. A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease. Blood. 2011 Nov 17; 118(20):5401-8. PMID: 21926355; PMCID: PMC3217345.
    Citations: 1     Fields:    Translation:HumansCells
  70. Paulo JA, Urrutia R, Banks PA, Conwell DL, Steen H. Proteomic analysis of an immortalized mouse pancreatic stellate cell line identifies differentially-expressed proteins in activated vs nonproliferating cell states. J Proteome Res. 2011 Oct 07; 10(10):4835-44. PMID: 21838295; PMCID: PMC3189387.
    Citations: 21     Fields:    Translation:AnimalsCells
  71. Younis AE, Geisinger F, Ajonina-Ekoti I, Soblik H, Steen H, Mitreva M, Erttmann KD, Perbandt M, Liebau E, Brattig NW. Stage-specific excretory-secretory small heat shock proteins from the parasitic nematode Strongyloides ratti--putative links to host's intestinal mucosal defense system. FEBS J. 2011 Sep; 278(18):3319-36. PMID: 21762402; PMCID: PMC3718022.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  72. Lysaght AC, Kao SY, Paulo JA, Merchant SN, Steen H, Stankovic KM. Proteome of human perilymph. J Proteome Res. 2011 Sep 02; 10(9):3845-51. PMID: 21740021; PMCID: PMC3179892.
    Citations: 11     Fields:    Translation:Humans
  73. Dowal L, Yang W, Freeman MR, Steen H, Flaumenhaft R. Proteomic analysis of palmitoylated platelet proteins. Blood. 2011 Sep 29; 118(13):e62-73. PMID: 21813449; PMCID: PMC3186346.
    Citations: 34     Fields:    Translation:HumansCells
  74. Paulo JA, Lee LS, Banks PA, Steen H, Conwell DL. Difference gel electrophoresis identifies differentially expressed proteins in endoscopically collected pancreatic fluid. Electrophoresis. 2011 Aug; 32(15):1939-51. PMID: 21792986; PMCID: PMC3374332.
    Citations: 5     Fields:    Translation:Humans
  75. Paulo JA, Lee LS, Wu B, Banks PA, Steen H, Conwell DL. Cytokine profiling of pancreatic fluid using the ePFT collection method in tandem with a multiplexed microarray assay. J Immunol Methods. 2011 Jun 30; 369(1-2):98-107. PMID: 21569776; PMCID: PMC3116066.
    Citations: 8     Fields:    Translation:Humans
  76. Prabakaran S, Everley RA, Landrieu I, Wieruszeski JM, Lippens G, Steen H, Gunawardena J. Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions. Mol Syst Biol. 2011 Apr 12; 7:482. PMID: 21487401; PMCID: PMC3097084.
    Citations: 21     Fields:    Translation:AnimalsCells
  77. Yang W, Chung YG, Kim Y, Kim TK, Keay SK, Zhang CO, Ji M, Hwang D, Kim KP, Steen H, Freeman MR, Kim J. Quantitative proteomics identifies a beta-catenin network as an element of the signaling response to Frizzled-8 protein-related antiproliferative factor. Mol Cell Proteomics. 2011 Jun; 10(6):M110.007492. PMID: 21422242; PMCID: PMC3108841.
    Citations: 12     Fields:    Translation:HumansCells
  78. Paulo JA, Lee LS, Wu B, Banks PA, Steen H, Conwell DL. Mass spectrometry-based proteomics of endoscopically collected pancreatic fluid in chronic pancreatitis research. Proteomics Clin Appl. 2011 Apr; 5(3-4):109-20. PMID: 21360826; PMCID: PMC3085141.
    Citations: 11     Fields:    Translation:Humans
  79. Kirchner M, Xu B, Steen H, Steen JA. libfbi: a C++ implementation for fast box intersection and application to sparse mass spectrometry data. Bioinformatics. 2011 Apr 15; 27(8):1166-7. PMID: 21330291.
    Citations: 2     Fields:    
  80. Vaezzadeh AR, Briscoe AC, Steen H, Lee RS. One-step sample concentration, purification, and albumin depletion method for urinary proteomics. J Proteome Res. 2010 Nov 05; 9(11):6082-9. PMID: 20923230; PMCID: PMC2974758.
    Citations: 6     Fields:    Translation:Humans
  81. Armand P, Kim HT, Rhodes J, Sainvil MM, Cutler C, Ho VT, Koreth J, Alyea EP, Hearsey D, Neufeld EJ, Fleming MD, Steen H, Anderson D, Kwong RY, Soiffer RJ, Antin JH. Iron overload in patients with acute leukemia or MDS undergoing myeloablative stem cell transplantation. Biol Blood Marrow Transplant. 2011 Jun; 17(6):852-60. PMID: 20854920; PMCID: PMC3954514.
    Citations: 17     Fields:    Translation:Humans
  82. Paulo JA, Lee LS, Wu B, Repas K, Banks PA, Conwell DL, Steen H. Proteomic analysis of endoscopically (endoscopic pancreatic function test) collected gastroduodenal fluid using in-gel tryptic digestion followed by LC-MS/MS. Proteomics Clin Appl. 2010 Sep; 4(8-9):715-25. PMID: 21137089; PMCID: PMC3210639.
    Citations: 14     Fields:    Translation:Humans
  83. Paulo JA, Lee LS, Wu B, Repas K, Mortele KJ, Banks PA, Steen H, Conwell DL. Identification of pancreas-specific proteins in endoscopically (endoscopic pancreatic function test) collected pancreatic fluid with liquid chromatography--tandem mass spectrometry. Pancreas. 2010 Aug; 39(6):889-96. PMID: 20182389; PMCID: PMC2891328.
    Citations: 17     Fields:    Translation:Humans
  84. Paulo JA, Lee LS, Wu B, Repas K, Banks PA, Conwell DL, Steen H. Optimized sample preparation of endoscopic collected pancreatic fluid for SDS-PAGE analysis. Electrophoresis. 2010 Jul; 31(14):2377-87. PMID: 20589857; PMCID: PMC3019099.
    Citations: 13     Fields:    Translation:HumansCells
  85. Yang W, Cai Q, Lui VW, Everley PA, Kim J, Bhola N, Quesnelle KM, Zetter BR, Steen H, Freeman MR, Grandis JR. Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer. J Proteome Res. 2010 Jun 04; 9(6):3073-82. PMID: 20426488.
    Citations: 7     Fields:    Translation:HumansCells
  86. Renard BY, Timm W, Kirchner M, Steen JA, Hamprecht FA, Steen H. Estimating the confidence of peptide identifications without decoy databases. Anal Chem. 2010 Jun 01; 82(11):4314-8. PMID: 20455556.
    Citations: 10     Fields:    Translation:HumansAnimals
  87. Timm W, Ozlu N, Steen JJ, Steen H. Effect of high-accuracy precursor masses on phosphopeptide identification from MS3 spectra. Anal Chem. 2010 May 15; 82(10):3977-80. PMID: 20426395.
    Citations: 2     Fields:    Translation:Cells
  88. Kirchner M, Steen JA, Hamprecht FA, Steen H. MGFp: an open Mascot Generic Format parser library implementation. J Proteome Res. 2010 May 07; 9(5):2762-3. PMID: 20334363.
    Citations: 2     Fields:    
  89. Lou X, Kirchner M, Renard BY, Köthe U, Boppel S, Graf C, Lee CT, Steen JA, Steen H, Mayer MP, Hamprecht FA. Deuteration distribution estimation with improved sequence coverage for HX/MS experiments. Bioinformatics. 2010 Jun 15; 26(12):1535-41. PMID: 20439256.
    Citations: 17     Fields:    
  90. Ozlu N, Akten B, Timm W, Haseley N, Steen H, Steen JAJ. Phosphoproteomics. Wiley Interdiscip Rev Syst Biol Med. 2010 May-Jun; 2(3):255-276. PMID: 20836028.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  91. Prisic S, Dankwa S, Schwartz D, Chou MF, Locasale JW, Kang CM, Bemis G, Church GM, Steen H, Husson RN. Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7521-6. PMID: 20368441; PMCID: PMC2867705.
    Citations: 71     Fields:    Translation:Cells
  92. Anderson DS, Heeney MM, Roth U, Menzel C, Fleming MD, Steen H. High-throughput matrix-assisted laser desorption ionization-time-of-flight mass spectrometry method for quantification of hepcidin in human urine. Anal Chem. 2010 Feb 15; 82(4):1551-5. PMID: 20102179; PMCID: PMC2830621.
    Citations: 6     Fields:    Translation:Humans
  93. Kirchner M, Timm W, Fong P, Wangemann P, Steen H. Non-linear classification for on-the-fly fractional mass filtering and targeted precursor fragmentation in mass spectrometry experiments. Bioinformatics. 2010 Mar 15; 26(6):791-7. PMID: 20134030; PMCID: PMC3202308.
    Citations: 6     Fields:    
  94. Renard BY, Kirchner M, Monigatti F, Ivanov AR, Rappsilber J, Winter D, Steen JA, Hamprecht FA, Steen H. When less can yield more - Computational preprocessing of MS/MS spectra for peptide identification. Proteomics. 2009 Nov; 9(21):4978-84. PMID: 19743429.
    Citations: 22     Fields:    Translation:HumansAnimals
  95. Kirchner M, Renard BY, Köthe U, Pappin DJ, Hamprecht FA, Steen H, Steen JA. Computational protein profile similarity screening for quantitative mass spectrometry experiments. Bioinformatics. 2010 Jan 01; 26(1):77-83. PMID: 19861354.
    Citations: 6     Fields:    Translation:Cells
  96. Yang W, Di Vizio D, Kirchner M, Steen H, Freeman MR. Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. Mol Cell Proteomics. 2010 Jan; 9(1):54-70. PMID: 19801377; PMCID: PMC2808267.
    Citations: 101     Fields:    Translation:HumansCells
  97. Ozlü N, Monigatti F, Renard BY, Field CM, Steen H, Mitchison TJ, Steen JJ. Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Mol Cell Proteomics. 2010 Feb; 9(2):336-50. PMID: 19786723; PMCID: PMC2830844.
    Citations: 31     Fields:    Translation:HumansCells
  98. Kentsis A, Monigatti F, Dorff K, Campagne F, Bachur R, Steen H. Urine proteomics for profiling of human disease using high accuracy mass spectrometry. Proteomics Clin Appl. 2009 Sep 01; 3(9):1052-1061. PMID: 21127740.
    Citations: 34     Fields:    
  99. Tazir Y, Steisslinger V, Soblik H, Younis AE, Beckmann S, Grevelding CG, Steen H, Brattig NW, Erttmann KD. Molecular and functional characterisation of the heat shock protein 10 of Strongyloides ratti. Mol Biochem Parasitol. 2009 Dec; 168(2):149-57. PMID: 19643150.
    Citations: 12     Fields:    Translation:AnimalsCells
  100. Vaezzadeh AR, Steen H, Freeman MR, Lee RS. Proteomics and opportunities for clinical translation in urological disease. J Urol. 2009 Sep; 182(3):835-43. PMID: 19616261; PMCID: PMC4370209.
    Citations: 4     Fields:    Translation:Humans
  101. Kentsis A, Lin YY, Kurek K, Calicchio M, Wang YY, Monigatti F, Campagne F, Lee R, Horwitz B, Steen H, Bachur R. Discovery and validation of urine markers of acute pediatric appendicitis using high-accuracy mass spectrometry. Ann Emerg Med. 2010 Jan; 55(1):62-70.e4. PMID: 19556024; PMCID: PMC4422167.
    Citations: 29     Fields:    Translation:Humans
  102. Huang H, Yu M, Akie TE, Moran TB, Woo AJ, Tu N, Waldon Z, Lin YY, Steen H, Cantor AB. Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development. Mol Cell Biol. 2009 Aug; 29(15):4103-15. PMID: 19470763; PMCID: PMC2715817.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  103. Singh S, Springer M, Steen J, Kirschner MW, Steen H. FLEXIQuant: a novel tool for the absolute quantification of proteins, and the simultaneous identification and quantification of potentially modified peptides. J Proteome Res. 2009 May; 8(5):2201-10. PMID: 19344176; PMCID: PMC2868505.
    Citations: 27     Fields:    Translation:HumansCells
  104. Jorgensen P, Steen JA, Steen H, Kirschner MW. The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus. Development. 2009 May; 136(9):1539-48. PMID: 19363155.
    Citations: 20     Fields:    Translation:AnimalsCells
  105. Wang Z, Dong G, Singh S, Steen H, Li J. A simple and effective method for detecting phosphopeptides for phosphoproteomic analysis. J Proteomics. 2009 Jul 21; 72(5):831-5. PMID: 19341826.
    Citations: 5     Fields:    Translation:AnimalsCells
  106. Kentsis A, Monigatti F, Dorff K, Campagne F, Bachur R, Steen H. Urine proteomics for profiling of human disease using high accuracy mass spectrometry. Proteomics Clin Appl. 2009; 3:1052-61.
  107. Renard BY, Kirchner M, Steen H, Steen JA, Hamprecht FA. NITPICK: peak identification for mass spectrometry data. BMC Bioinformatics. 2008 Aug 28; 9:355. PMID: 18755032; PMCID: PMC2655099.
    Citations: 30     Fields:    
  108. Koenig T, Menze BH, Kirchner M, Monigatti F, Parker KC, Patterson T, Steen JJ, Hamprecht FA, Steen H. Robust prediction of the MASCOT score for an improved quality assessment in mass spectrometric proteomics. J Proteome Res. 2008 Sep; 7(9):3708-17. PMID: 18707158.
    Citations: 35     Fields:    
  109. Lee RS, Monigatti F, Briscoe AC, Waldon Z, Freeman MR, Steen H. Optimizing sample handling for urinary proteomics. J Proteome Res. 2008 Sep; 7(9):4022-30. PMID: 18662026.
    Citations: 23     Fields:    Translation:HumansCells
  110. Adam RM, Yang W, Di Vizio D, Mukhopadhyay NK, Steen H. Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis. BMC Cell Biol. 2008 Jun 05; 9:30. PMID: 18534013; PMCID: PMC2440737.
    Citations: 19     Fields:    Translation:HumansCells
  111. Steen H, Stensballe A, Jensen ON. Alkaline Phosphatase Treatment of Phosphopeptides: On-Probe Dephosphorylation after MALDI-MS Analysis. CSH Protoc. 2008 May 01; 2008:pdb.prot4612. PMID: 21356824.
    Citations:    
  112. Steen H, Stensballe A, Jensen ON. Alkaline Phosphatase Treatment of Phosphopeptides: In-Solution Dephosphorylation after MALDI-MS Analysis. CSH Protoc. 2008 May 01; 2008:pdb.prot4611. PMID: 21356823.
    Citations:    
  113. Steen H, Stensballe A, Jensen ON. Alkaline Phosphatase Treatment of Phosphopeptides: In-Solution Dephosphorylation prior to MALDI-MS Analysis. CSH Protoc. 2008 May 01; 2008:pdb.prot4610. PMID: 21356822.
    Citations:    
  114. Steen JA, Steen H, Georgi A, Parker K, Springer M, Kirchner M, Hamprecht F, Kirschner MW. Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis. Proc Natl Acad Sci U S A. 2008 Apr 22; 105(16):6069-74. PMID: 18420821; PMCID: PMC2329673.
    Citations: 41     Fields:    Translation:HumansCells
  115. Monigatti F, Steen H. SALAMI (Spectrum ALignments using high Accuracy Mass and hIgh sensitivity data): how to make the best out of hybrid MS/MS data. J Proteome Res. 2008 May; 7(5):1984-93. PMID: 18407685.
    Citations: 1     Fields:    Translation:AnimalsCells
  116. Lee RS, Monigatti F, Lutchman M, Patterson T, Budnik B, Steen JA, Freeman MR, Steen H. Temporal variations of the postnatal rat urinary proteome as a reflection of systemic maturation. Proteomics. 2008 Mar; 8(5):1097-112. PMID: 18324733.
    Citations: 6     Fields:    Translation:Animals
  117. Yang W, Steen H, Freeman MR. Proteomic approaches to the analysis of multiprotein signaling complexes. Proteomics. 2008 Feb; 8(4):832-51. PMID: 18297654.
    Citations: 16     Fields:    Translation:Cells
  118. Steen H, Stensballe A, Jensen ON. Preparation and Use of Microcolumns for Sample Desalting or Nanoscale IMAC. CSH Protoc. 2007 Nov 01; 2007:pdb.prot4608. PMID: 21356964.
    Citations:    
  119. Steen H, Stensballe A, Jensen ON. Phosphopeptide Purification by IMAC with Fe(III) and Ga(III). CSH Protoc. 2007 Nov 01; 2007:pdb.prot4607. PMID: 21356963.
    Citations: 2     
  120. Kirchner M, Saussen B, Steen H, Steen JAJ, Hamprecht FA. amsrpm: Robust Point Matching for Retention Time Alignment of LC/MS Data with R. J Stat Software. 2007; 18:4.
  121. Bensadek D, Monigatti F, Steen JAJ, Steen H. Why b, y’s? Sodiation-induced tryptic peptide-like fragmentation of non-tryptic peptides. Int J Mass Spectrom. 2007; 268:181-189.
  122. Monigatti F, Hekking B, Steen H. Protein sulfation analysis--A primer. Biochim Biophys Acta. 2006 Dec; 1764(12):1904-13. PMID: 16952486.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  123. MacLellan DL, Steen H, Adam RM, Garlick M, Zurakowski D, Gygi SP, Freeman MR, Solomon KR. A quantitative proteomic analysis of growth factor-induced compositional changes in lipid rafts of human smooth muscle cells. Proteomics. 2005 Dec; 5(18):4733-42. PMID: 16267816.
    Citations: 26     Fields:    Translation:HumansCells
  124. Steen H, Jebanathirajah JA, Rush J, Morrice N, Kirschner MW. Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements. Mol Cell Proteomics. 2006 Jan; 5(1):172-81. PMID: 16204703.
    Citations: 74     Fields:    Translation:Cells
  125. Steen H, Jebanathirajah JA, Springer M, Kirschner MW. Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS. Proc Natl Acad Sci U S A. 2005 Mar 15; 102(11):3948-53. PMID: 15741271; PMCID: PMC552780.
    Citations: 56     Fields:    Translation:AnimalsCells
  126. Auty R, Steen H, Myers LC, Persinger J, Bartholomew B, Gygi SP, Buratowski S. Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function. J Biol Chem. 2004 Nov 26; 279(48):49973-81. PMID: 15448131.
    Citations: 16     Fields:    Translation:AnimalsCells
  127. Steen H, Mann M. The ABC's (and XYZ's) of peptide sequencing. Nat Rev Mol Cell Biol. 2004 Sep; 5(9):699-711. PMID: 15340378.
    Citations: 191     Fields:    Translation:Cells
  128. Argetsinger LS, Kouadio JL, Steen H, Stensballe A, Jensen ON, Carter-Su C. Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity. Mol Cell Biol. 2004 Jun; 24(11):4955-67. PMID: 15143187; PMCID: PMC416404.
    Citations: 38     Fields:    Translation:AnimalsCells
  129. Gautreau A, Ho HY, Li J, Steen H, Gygi SP, Kirschner MW. Purification and architecture of the ubiquitous Wave complex. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4379-83. PMID: 15070726; PMCID: PMC384755.
    Citations: 87     Fields:    Translation:HumansCells
  130. Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V, Niranjan V, Muthusamy B, Gandhi TK, Gronborg M, Ibarrola N, Deshpande N, Shanker K, Shivashankar HN, Rashmi BP, Ramya MA, Zhao Z, Chandrika KN, Padma N, Harsha HC, Yatish AJ, Kavitha MP, Menezes M, Choudhury DR, Suresh S, Ghosh N, Saravana R, Chandran S, Krishna S, Joy M, Anand SK, Madavan V, Joseph A, Wong GW, Schiemann WP, Constantinescu SN, Huang L, Khosravi-Far R, Steen H, Tewari M, Ghaffari S, Blobe GC, Dang CV, Garcia JG, Pevsner J, Jensen ON, Roepstorff P, Deshpande KS, Chinnaiyan AM, Hamosh A, Chakravarti A, Pandey A. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res. 2003 Oct; 13(10):2363-71. PMID: 14525934; PMCID: PMC403728.
    Citations: 356     Fields:    Translation:HumansCells
  131. Li J, Steen H, Gygi SP. Protein profiling with cleavable isotope-coded affinity tag (cICAT) reagents: the yeast salinity stress response. Mol Cell Proteomics. 2003 Nov; 2(11):1198-204. PMID: 14506205.
    Citations: 31     Fields:    Translation:AnimalsCells
  132. Jebanathirajah J, Steen H, Roepstorff P. Using optimized collision energies and high resolution, high accuracy fragment ion selection to improve glycopeptide detection by precursor ion scanning. J Am Soc Mass Spectrom. 2003 Jul; 14(7):777-84. PMID: 12837600.
    Citations: 16     Fields:    Translation:AnimalsCells
  133. Steen H, Fernandez M, Ghaffari S, Pandey A, Mann M. Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning. Mol Cell Proteomics. 2003 Mar; 2(3):138-45. PMID: 12644574.
    Citations: 8     Fields:    Translation:HumansCells
  134. Steen H, Mann M. Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags. Anal Chem. 2002 Dec 15; 74(24):6230-6. PMID: 12510743.
    Citations: 11     Fields:    Translation:Animals
  135. Steen H, Pandey A, Andersen JS, Mann M. Analysis of tyrosine phosphorylation sites in signaling molecules by a phosphotyrosine-specific immonium ion scanning method. Sci STKE. 2002 Oct 15; 2002(154):pl16. PMID: 12381836.
    Citations: 12     Fields:    Translation:HumansCells
  136. Steen H, Pandey A. Proteomics goes quantitative: measuring protein abundance. Trends Biotechnol. 2002 Sep; 20(9):361-4. PMID: 12175758.
    Citations: 11     Fields:    
  137. Steen H, Mann M. A new derivatization strategy for the analysis of phosphopeptides by precursor ion scanning in positive ion mode. J Am Soc Mass Spectrom. 2002 Aug; 13(8):996-1003. PMID: 12216740.
    Citations: 12     Fields:    Translation:Cells
  138. Mann M, Ong SE, Grønborg M, Steen H, Jensen ON, Pandey A. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends Biotechnol. 2002 Jun; 20(6):261-8. PMID: 12007495.
    Citations: 172     Fields:    Translation:AnimalsCells
  139. Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, Mann M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics. 2002 May; 1(5):376-86. PMID: 12118079.
    Citations: 1481     Fields:    Translation:AnimalsCells
  140. Steen H, Jensen ON. Analysis of protein-nucleic acid interactions by photochemical cross-linking and mass spectrometry. Mass Spectrom Rev. 2002 May-Jun; 21(3):163-82. PMID: 12476441.
    Citations: 20     Fields:    Translation:Cells
  141. Andersen JS, Rappsilber J, Steen H, Pandey A, Molina H, Lund M, Podtelejnikov A, Lamond AI, Mann M. Multi-Protein Complexes Studied by Mass Spectrometry. ScientificWorldJournal. 2002; 2:91-92. PMID: 29973817.
    Citations:    Fields:    
  142. Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI. Directed proteomic analysis of the human nucleolus. Curr Biol. 2002 Jan 08; 12(1):1-11. PMID: 11790298.
    Citations: 303     Fields:    Translation:HumansCells
  143. Peri S, Steen H, Pandey A. GPMAW--a software tool for analyzing proteins and peptides. Trends Biochem Sci. 2001 Nov; 26(11):687-9. PMID: 11701329.
    Citations: 27     Fields:    Translation:Cells
  144. Steen H, Kuster B, Fernandez M, Pandey A, Mann M. Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway. J Biol Chem. 2002 Jan 11; 277(2):1031-9. PMID: 11687594.
    Citations: 34     Fields:    Translation:HumansCells
  145. Steen H, Petersen J, Mann M, Jensen ON. Mass spectrometric analysis of a UV-cross-linked protein-DNA complex: tryptophans 54 and 88 of E. coli SSB cross-link to DNA. Protein Sci. 2001 Oct; 10(10):1989-2001. PMID: 11567090; PMCID: PMC2374209.
    Citations: 16     Fields:    Translation:Cells
  146. Steen H, Küster B, Mann M. Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning. J Mass Spectrom. 2001 Jul; 36(7):782-90. PMID: 11473401.
    Citations: 22     Fields:    Translation:Cells
  147. Rappsilber J, Steen H, Mann M. Labile sulfogroup allows differentiation of sulfotyrosine and phosphotyrosine in peptides. J Mass Spectrom. 2001 Jul; 36(7):832-3. PMID: 11473407.
    Citations: 4     Fields:    
  148. Petersson AS, Steen H, Kalume DE, Caidahl K, Roepstorff P. Investigation of tyrosine nitration in proteins by mass spectrometry. J Mass Spectrom. 2001 Jun; 36(6):616-25. PMID: 11433534.
    Citations: 23     Fields:    Translation:Cells
  149. Steen H, Küster B, Fernandez M, Pandey A, Mann M. Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode. Anal Chem. 2001 Apr 01; 73(7):1440-8. PMID: 11321292.
    Citations: 56     Fields:    Translation:HumansCells
  150. Spada F, Steen H, Troedsson C, Kallesoe T, Spriet E, Mann M, Thompson EM. Molecular patterning of the oikoplastic epithelium of the larvacean tunicate Oikopleura dioica. J Biol Chem. 2001 Jun 08; 276(23):20624-32. PMID: 11279070.
    Citations: 13     Fields:    Translation:AnimalsCells
  151. Steen H, Mann M. Similarity between condensed phase and gas phase chemistry: fragmentation of peptides containing oxidized cysteine residues and its implications for proteomics. J Am Soc Mass Spectrom. 2001 Feb; 12(2):228-32. PMID: 11212008.
    Citations: 21     Fields:    Translation:Cells
  152. Steen, H. Mass Spectrometry for the Analysis of Protein Modifications (Ph.D. Thesis). 2001.
  153. Pandey A, Fernandez MM, Steen H, Blagoev B, Nielsen MM, Roche S, Mann M, Lodish HF. Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways. J Biol Chem. 2000 Dec 08; 275(49):38633-9. PMID: 10993906.
    Citations: 21     Fields:    Translation:HumansCells
  154. Dahle J, Mikalsen SO, Rivedal E, Steen HB. Gap junctional intercellular communication is not a major mediator in the bystander effect in photodynamic treatment of MDCK II cells. Radiat Res. 2000 Sep; 154(3):331-41. PMID: 10956441.
    Citations: 3     Fields:    Translation:AnimalsCells
  155. Dahle J, Bagdonas S, Kaalhus O, Olsen G, Steen HB, Moan J. The bystander effect in photodynamic inactivation of cells. Biochim Biophys Acta. 2000 Jul 26; 1475(3):273-80. PMID: 10913826.
    Citations: 8     Fields:    Translation:AnimalsCells
  156. Gobom J, Kraeuter KO, Persson R, Steen H, Roepstorff P, Ekman R. Detection and quantification of neurotensin in human brain tissue by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Chem. 2000 Jul 15; 72(14):3320-6. PMID: 10939406.
    Citations: 8     Fields:    Translation:Humans
  157. Summerfield SG, Steen H, O’Malley M, Gaskell SJ. Phenyl thiocarbamoyl and related derivatives of peptides: Edman chemistry in the gas phase. Int J Mass Spectrom. 1999; 188:95-103.
  158. Studer A, Steen H. The SHi Reaction at Silicon – A New Entry into Cyclic Alkoxy-silanes. Chem Eur J. 1999; 5:759-73.
  159. Studer A, Bossart M, Steen H. Stereoselective Phenyl Migration from Silicon to Carbon. Tetrahedron Lett. 1998; 39:8829-32.
  160. Steen, H. Intramolecular Homolytic Substitution on Silicon – Influence of the Degree of Substitution on the Rate of Cyclisation (Dipl. Chem. Thesis). 1998.
  161. Steen, H. Techniques for the Mass Spectrometric Localisation of Double Bonds (B.Sc. Thesis). 1995.
  162. Wold S, Skarstad K, Steen HB, Stokke T, Boye E. The initiation mass for DNA replication in Escherichia coli K-12 is dependent on growth rate. EMBO J. 1994 May 01; 13(9):2097-102. PMID: 8187762; PMCID: PMC395061.
    Citations: 44     Fields:    Translation:Cells
  163. Kvam E, Berg K, Steen HB. Characterization of singlet oxygen-induced guanine residue damage after photochemical treatment of free nucleosides and DNA. Biochim Biophys Acta. 1994 Jan 18; 1217(1):9-15. PMID: 8286420.
    Citations: 3     Fields:    
  164. Kvam E, Stokke T, Moan J, Steen HB. Plateau distributions of DNA fragment lengths produced by extended light exposure of extranuclear photosensitizers in human cells. Nucleic Acids Res. 1992 Dec 25; 20(24):6687-93. PMID: 1480490; PMCID: PMC334587.
    Citations:    Fields:    Translation:HumansCells
  165. Stokke T, Holte H, Smeland EB, Lie SO, Steen HB. Differential chromatin structure-dependent binding of 7-aminoactinomycin D in normal and malignant bone marrow hematopoietic cells. Cancer Res. 1992 Sep 15; 52(18):5007-12. PMID: 1516056.
    Citations:    Fields:    Translation:HumansCells
  166. Berg K, Steen HB, Winkelman JW, Moan J. Synergistic effects of photoactivated tetra(4-sulfonatophenyl)porphine and nocodazole on microtubule assembly, accumulation of cells in mitosis and cell survival. J Photochem Photobiol B. 1992 Apr 15; 13(1):59-70. PMID: 1403369.
    Citations: 3     Fields:    Translation:HumansCells
  167. Stokke T, Erikstein B, Holte H, Funderud S, Steen HB. Cell cycle-specific expression and nuclear binding of DNA polymerase alpha. Mol Cell Biol. 1991 Jun; 11(6):3384-9. PMID: 2038340; PMCID: PMC360194.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  168. Stokke T, Steen HB. Fluorescence spectra of Hoechst 33258 bound to chromatin. Biochim Biophys Acta. 1986 Oct 16; 868(1):17-23. PMID: 2428400.
    Citations: 2     Fields:    Translation:AnimalsCells
  169. Skarstad K, Boye E, Steen HB. Timing of initiation of chromosome replication in individual Escherichia coli cells. EMBO J. 1986 Jul; 5(7):1711-7. PMID: 3527695; PMCID: PMC1166998.
    Citations: 136     Fields:    Translation:Cells
  170. Stokke T, Steen HB. Neither adriamycin nor actinomycin D displaces Tb3+ from DNA. Biochim Biophys Acta. 1985 Aug 21; 825(4):416-8. PMID: 4016123.
    Citations:    Fields:    Translation:Cells
  171. Steen HB, Munthe-Kaas AC. Promotive and inhibitory effects of macrophages on the mitogen-induced blastogenesis of lymphocytes: a flow-cytometric study. Scand J Immunol. 1981 Jul; 14(1):39-46. PMID: 6797048.
    Citations: 2     Fields:    Translation:AnimalsCells
  172. Steen HB. Further developments of a microscope-based flow cytometer: light scatter detection and excitation intensity compensation. Cytometry. 1980 Jul; 1(1):26-31. PMID: 7273962.
    Citations: 6     Fields:    Translation:HumansCells
  173. Steen HB. Molecular excitations in radiation damage as studies by the radiation-induced luminescence of proteins. Scand J Clin Lab Invest Suppl. 1968; 106:21-30. PMID: 5731705.
    Citations:    Fields:    Translation:Cells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.