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Aarti Asnani, M.D.

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Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL163172 (ASNANI, AARTI) Apr 1, 2022 - Mar 31, 2027
    NIH
    Hemopexin as an Early Biomarker of Anthracycline Cardiac Toxicity
    Role: Principal Investigator
  2. R01HL157530 (YEH, ROBERT) Apr 1, 2021 - Mar 31, 2025
    NIH
    A Multi-Dimensional Linked Registry to Identify Biological, Clinical, Health System, and Socioeconomic Risk Factors for COVID-19-Related Cardiovascular Events
    Role: Co-Investigator
  3. R21HL148748 (ASNANI, AARTI) Aug 1, 2019 - Jul 31, 2021
    NIH
    Sex-Specific Differences in the Development of Anthracycline Cardiotoxicity
    Role: Principal Investigator
  4. K08HL145019 (ASNANI, AARTI) Jan 15, 2019 - Dec 31, 2023
    NIH
    CYP1 Inhibition as a New Therapeutic Strategy for Doxorubicin Cardiomyopathy
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kumar A, Ravi R, Sivakumar RK, Chidambaram V, Majella MG, Sinha S, Adamo L, Lau ES, Al'Aref SJ, Asnani A, Sharma G, Mehta JL. Prolactin Inhibition in Peripartum Cardiomyopathy: Systematic Review and Meta-analysis. Curr Probl Cardiol. 2022 Oct 17; 48(2):101461. PMID: 36261102.
    Citations:    Fields:    
  2. Abraham S, Nohria A, Neilan TG, Asnani A, Saji AM, Shah J, Lech T, Grossman J, Abraham GM, McQuillen DP, Martin DT, Sax PE, Dani SS, Ganatra S. Cardiovascular Drug Interactions With Nirmatrelvir/Ritonavir in Patients With COVID-19: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 Nov 15; 80(20):1912-1924. PMID: 36243540; PMCID: PMC9580069.
    Citations:    Fields:    Translation:HumansPHPublic Health
  3. Ganatra S, Dani SS, Kumar A, Khan SU, Wadhera R, Neilan TG, Thavendiranathan P, Barac A, Hermann J, Leja M, Deswal A, Fradley M, Liu JE, Sadler D, Asnani A, Baldassarre LA, Gupta D, Yang E, Guha A, Brown SA, Stevens J, Hayek SS, Porter C, Kalra A, Baron SJ, Ky B, Virani SS, Kazi D, Nasir K, Nohria A. Impact of Social Vulnerability on Comorbid Cancer and Cardiovascular Disease Mortality in the United States. JACC CardioOncol. 2022 Sep; 4(3):326-337. PMID: 36213357; PMCID: PMC9537091.
    Citations:    
  4. Oseran AS, Sun T, Wadhera RK, Dahabreh IJ, de Lemos JA, Das SR, Rutan C, Asnani AH, Yeh RW, Kazi DS. Enriching the American Heart Association COVID-19 Cardiovascular Disease Registry Through Linkage With External Data Sources: Rationale and Design. J Am Heart Assoc. 2022 09 20; 11(18):e7743. PMID: 36102226.
    Citations:    Fields:    Translation:Humans
  5. Liu J, Chen ZZ, Patel J, Asnani A. Understanding Myocardial Metabolism in the Context of Cardio-Oncology. Heart Fail Clin. 2022 Jul; 18(3):415-424. PMID: 35718416.
    Citations:    Fields:    Translation:Humans
  6. Power JR, Alexandre J, Choudhary A, Ozbay B, Hayek SS, Asnani A, Tamura Y, Aras M, Cautela J, Thuny F, Gilstrap L, Arangalage D, Ewer S, Huang S, Deswal A, Palaskas NL, Finke D, Lehmann LH, Ederhy S, Moslehi J, Salem JE. Association of early electrical changes with cardiovascular outcomes in immune checkpoint inhibitor myocarditis. Arch Cardiovasc Dis. 2022 May; 115(5):315-330. PMID: 35595646.
    Citations:    Fields:    Translation:Humans
  7. Al-Otaibi TK, Weitzman B, Tahir UA, Asnani A. Genetics of Anthracycline-Associated Cardiotoxicity. Front Cardiovasc Med. 2022; 9:867873. PMID: 35528837; PMCID: PMC9068960.
    Citations:    
  8. Menon AV, Liu J, Tsai HP, Zeng L, Yang S, Asnani A, Kim J. Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease. Blood. 2022 02 10; 139(6):936-941. PMID: 34388243; PMCID: PMC8832481.
    Citations: 10     Fields:    Translation:Animals
  9. Obasi M, Abovich A, Vo JB, Gao Y, Papatheodorou SI, Nohria A, Asnani A, Partridge AH. Correction to: Statins to mitigate cardiotoxicity in cancer patients treated with anthracyclines and/or trastuzumab: a systematic review and meta-analysis. Cancer Causes Control. 2021 Dec; 32(12):1407-1409. PMID: 34533664; PMCID: PMC9172661.
    Citations: 1     Fields:    
  10. Raber I, Al Rifai M, McCarthy CP, Vaduganathan M, Michos ED, Wood MJ, Smyth YM, Ibrahim NE, Asnani A, Mehran R, McEvoy JW. Gender Differences in Medicare Payments Among Cardiologists. JAMA Cardiol. 2021 12 01; 6(12):1432-1439. PMID: 34495296; PMCID: PMC8427494.
    Citations:    Fields:    Translation:Humans
  11. Power JR, Alexandre J, Choudhary A, Ozbay B, Hayek S, Asnani A, Tamura Y, Aras M, Cautela J, Thuny F, Gilstrap L, Arangalage D, Ewer S, Huang S, Deswal A, Palaskas NL, Finke D, Lehman L, Ederhy S, Moslehi J, Salem JE. Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Myocarditis. Circulation. 2021 11 02; 144(18):1521-1523. PMID: 34723640; PMCID: PMC8567307.
    Citations: 8     Fields:    Translation:Humans
  12. Lehmann LH, Cautela J, Palaskas N, Baik AH, Meijers WC, Allenbach Y, Alexandre J, Rassaf T, Müller OJ, Aras M, Asnani AH, Deswal A, Laufer-Perl M, Thuny F, Kerneis M, Hayek SS, Ederhy S, Salem JE, Moslehi JJ. Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor-Associated Myocarditis: A Narrative Review. JAMA Cardiol. 2021 11 01; 6(11):1329-1337. PMID: 34232253.
    Citations: 8     Fields:    Translation:Humans
  13. Asnani A. Activating Autophagy to Prevent Doxorubicin Cardiomyopathy: The Timing Matters. Circ Res. 2021 10; 129(8):801-803. PMID: 34591656.
    Citations: 1     Fields:    Translation:Humans
  14. Obasi M, Abovich A, Vo JB, Gao Y, Papatheodorou SI, Nohria A, Asnani A, Partridge AH. Statins to mitigate cardiotoxicity in cancer patients treated with anthracyclines and/or trastuzumab: a systematic review and meta-analysis. Cancer Causes Control. 2021 Dec; 32(12):1395-1405. PMID: 34406595; PMCID: PMC8541988.
    Citations: 3     Fields:    Translation:Humans
  15. Asnani A, Moslehi JJ, Adhikari BB, Baik AH, Beyer AM, de Boer RA, Ghigo A, Grumbach IM, Jain S, Zhu H. Preclinical Models of Cancer Therapy-Associated Cardiovascular Toxicity: A Scientific Statement From the American Heart Association. Circ Res. 2021 06 25; 129(1):e21-e34. PMID: 33934611.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  16. More LA, Lane S, Asnani A. 5-FU Cardiotoxicity: Vasospasm, Myocarditis, and Sudden Death. Curr Cardiol Rep. 2021 02 03; 23(3):17. PMID: 33537861.
    Citations: 4     Fields:    Translation:Humans
  17. Lane S, More LA, Asnani A. Zebrafish Models of Cancer Therapy-Induced Cardiovascular Toxicity. J Cardiovasc Dev Dis. 2021 Jan 22; 8(2). PMID: 33499052.
    Citations: 1     
  18. Raines NH, Ganatra S, Nissaisorakarn P, Pandit A, Morales A, Asnani A, Sadrolashrafi M, Maheshwari R, Patel R, Bang V, Shreyder K, Brar S, Singh A, Dani SS, Knapp S, Poyan Mehr A, Brown RS, Zeidel ML, Bhargava R, Schlondorff J, Steinman TI, Mukamal KJ, Parikh SM. Niacinamide May Be Associated with Improved Outcomes in COVID-19-Related Acute Kidney Injury: An Observational Study. Kidney360. 2021 01 28; 2(1):33-41. PMID: 35368823; PMCID: PMC8785722.
    Citations:    Translation:Humans
  19. Ganatra S, Dani SS, Redd R, Rieger-Christ K, Patel R, Parikh R, Asnani A, Bang V, Shreyder K, Brar SS, Singh A, Kazi DS, Guha A, Hayek SS, Barac A, Gunturu KS, Zarwan C, Mosenthal AC, Yunus SA, Kumar A, Patel JM, Patten RD, Venesy DM, Shah SP, Resnic FS, Nohria A, Baron SJ. Outcomes of COVID-19 in Patients With a History of Cancer and Comorbid Cardiovascular Disease. J Natl Compr Canc Netw. 2020 Nov 03; 1-10. PMID: 33142266.
    Citations: 14     Fields:    
  20. Raber I, Peters ML, Asnani A. In Reply. Oncologist. 2020 08; 25(8):e1255-e1256. PMID: 32436313.
    Citations:    Fields:    Translation:Humans
  21. Raber I, Frazer MB, Zerillo JA, Asnani A. Uridine Triacetate for Severe Fluoropyrimidine Cardiotoxicity in a Patient With Thymidylate Synthase Gene Variants. JACC CardioOncol. 2020 Jun; 2(2):329-332. PMID: 34396241.
    Citations: 1     
  22. Ganatra S, Dani SS, Shah S, Asnani A, Neilan TG, Lenihan D, Ky B, Barac A, Hayek SS, Leja M, Herrmann J, Thavendiranathan P, Fradley M, Bang V, Shreyder K, Parikh R, Patel R, Singh A, Brar S, Guha A, Gupta D, Mascari P, Patten RD, Venesy DM, Nohria A, Resnic FS. Management of Cardiovascular Disease During Coronavirus Disease (COVID-19) Pandemic. Trends Cardiovasc Med. 2020 08; 30(6):315-325. PMID: 32474135.
    Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
  23. Piper-Vallillo AJ, Costa DB, Sabe MA, Asnani A. Heart Failure Associated With the Epidermal Growth Factor Receptor Inhibitor Osimertinib. JACC CardioOncol. 2020 Mar; 2(1):119-122. PMID: 34396216.
    Citations: 3     
  24. Lam PY, Kutchukian P, Anand R, Imbriglio J, Andrews C, Padilla H, Vohra A, Lane S, Parker DL, Cornella Taracido I, Johns DG, Beerens M, MacRae CA, Caldwell JP, Sorota S, Asnani A, Peterson RT. Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model. Chembiochem. 2020 07 01; 21(13):1905-1910. PMID: 32003101.
    Citations: 6     Fields:    Translation:Animals
  25. Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari SR, Mitchell K, Lopez A, Margulets V, Scarlata M, Santulli G, Asnani A, Peterson RT, Hazan RB, Condeelis JS, Oktay MH, Steidl U, Kirshenbaum LA, Gavathiotis E, Kitsis RN. A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy. Nat Cancer. 2020 03; 1(3):315-328. PMID: 32776015; PMCID: PMC7413180.
    Citations: 25     Translation:Animals
  26. Raber I, McCarthy CP, Al Rifai M, Vaduganathan M, Michos ED, Wood MJ, Smyth YM, Ibrahim NE, DeFaria Yeh D, Asnani A, Mehran R, McEvoy JW. Gender differences in industry payments among cardiologists. Am Heart J. 2020 05; 223:123-131. PMID: 31926591.
    Citations: 4     Fields:    Translation:Humans
  27. Raber I, Warack S, Kanduri J, Pribish A, Godishala A, Abovich A, Orbite A, Dommaraju S, Frazer M, Peters ML, Asnani A. Fluoropyrimidine-Associated Cardiotoxicity: A Retrospective Case-Control Study. Oncologist. 2020 03; 25(3):e606-e609. PMID: 32162823; PMCID: PMC7066698.
    Citations: 10     Fields:    Translation:Humans
  28. Kanduri J, More LA, Godishala A, Asnani A. Fluoropyrimidine-Associated Cardiotoxicity. Cardiol Clin. 2019 Nov; 37(4):399-405. PMID: 31587781.
    Citations: 16     Fields:    Translation:Humans
  29. Asnani A, Shi X, Farrell L, Lall R, Sebag IA, Plana JC, Gerszten RE, Scherrer-Crosbie M. Changes in Citric Acid Cycle and Nucleoside Metabolism Are Associated with Anthracycline Cardiotoxicity in Patients with Breast Cancer. J Cardiovasc Transl Res. 2020 06; 13(3):349-356. PMID: 31278494.
    Citations: 9     Fields:    Translation:HumansCells
  30. Raber I, Asnani A. Cardioprotection in cancer therapy: novel insights with anthracyclines. Cardiovasc Res. 2019 04 15; 115(5):915-921. PMID: 30726931.
    Citations: 6     Fields:    Translation:HumansAnimals
  31. Baumgartner C, Spath-Blass V, Niederkofler V, Bergmoser K, Langthaler S, Lassnig A, Rienmüller T, Baumgartner D, Asnani A, Gerszten RE. A novel network-based approach for discovering dynamic metabolic biomarkers in cardiovascular disease. PLoS One. 2018; 13(12):e0208953. PMID: 30533038; PMCID: PMC6289413.
    Citations: 3     Fields:    Translation:Humans
  32. Yang S, Asnani A. Cardiotoxicities associated with immune checkpoint inhibitors. Curr Probl Cancer. 2018 07; 42(4):422-432. PMID: 30173878.
    Citations: 20     Fields:    Translation:Humans
  33. Mukhopadhyay A, Faridi KF, Asnani A, Osborn EA, Yang JX, Phillips CT, York M. Chest Pain During Chemotherapy: A Case of Severe Myocardial Bridging. J Invasive Cardiol. 2018 Jul; 30(7):E61. PMID: 29958181.
    Citations:    Fields:    Translation:Humans
  34. Vohra A, Asnani A. Biomarker Discovery in Cardio-Oncology. Curr Cardiol Rep. 2018 05 25; 20(7):52. PMID: 29802472.
    Citations: 6     Fields:    Translation:Humans
  35. Asnani A. Beta-Blockers for Primary Prevention of Anthracycline Cardiotoxicity: Not Quite Ready for Prime Time. J Am Coll Cardiol. 2018 05 22; 71(20):2291-2292. PMID: 29773156.
    Citations: 1     Fields:    Translation:PHPublic Health
  36. Godishala A, Yang S, Asnani A. Cardioprotection in the Modern Era of Cancer Chemotherapy. Cardiol Rev. 2018 May/Jun; 26(3):113-121. PMID: 29608498.
    Citations: 2     Fields:    Translation:Humans
  37. Asnani A. Cardiotoxicity of Immunotherapy: Incidence, Diagnosis, and Management. Curr Oncol Rep. 2018 04 11; 20(6):44. PMID: 29644505.
    Citations: 15     Fields:    Translation:Humans
  38. Asnani A, Zheng B, Liu Y, Wang Y, Chen HH, Vohra A, Chi A, Cornella-Taracido I, Wang H, Johns DG, Sosnovik DE, Peterson RT. Highly potent visnagin derivatives inhibit Cyp1 and prevent doxorubicin cardiotoxicity. JCI Insight. 2018 01 11; 3(1). PMID: 29321375.
    Citations: 12     Fields:    Translation:AnimalsCells
  39. Asnani A, Manning A, Mansour M, Ruskin J, Hochberg EP, Ptaszek LM. Management of atrial fibrillation in patients taking targeted cancer therapies. Cardiooncology. 2017; 3:2. PMID: 32153998; PMCID: PMC7048041.
    Citations: 4     
  40. Francis SA, Asnani A, Neilan T, Scherrer-Crosbie M. Optimizing cardio-oncology programs for cancer patients. Future Oncol. 2015; 11(14):2011-5. PMID: 26198828.
    Citations: 2     Fields:    Translation:Humans
  41. Liu Y, Asnani A, Zou L, Bentley VL, Yu M, Wang Y, Dellaire G, Sarkar KS, Dai M, Chen HH, Sosnovik DE, Shin JT, Haber DA, Berman JN, Chao W, Peterson RT. Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. Sci Transl Med. 2014 Dec 10; 6(266):266ra170. PMID: 25504881; PMCID: PMC4360984.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  42. Asnani A, Peterson RT. The zebrafish as a tool to identify novel therapies for human cardiovascular disease. Dis Model Mech. 2014 Jul; 7(7):763-7. PMID: 24973746.
    Citations: 59     Fields:    Translation:HumansAnimals
  43. Gerszten RE, Asnani A, Carr SA. Status and prospects for discovery and verification of new biomarkers of cardiovascular disease by proteomics. Circ Res. 2011 Aug 05; 109(4):463-74. PMID: 21817166.
    Citations: 26     Fields:    Translation:HumansAnimals
  44. Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE. Metabolic signatures of exercise in human plasma. Sci Transl Med. 2010 May 26; 2(33):33ra37. PMID: 20505214.
    Citations: 160     Fields:    Translation:HumansAnimalsCells
  45. Lewis GD, Wei R, Liu E, Yang E, Shi X, Martinovic M, Farrell L, Asnani A, Cyrille M, Ramanathan A, Shaham O, Berriz G, Lowry PA, Palacios IF, Tasan M, Roth FP, Min J, Baumgartner C, Keshishian H, Addona T, Mootha VK, Rosenzweig A, Carr SA, Fifer MA, Sabatine MS, Gerszten RE. Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury. J Clin Invest. 2008 Oct; 118(10):3503-12. PMID: 18769631; PMCID: PMC2525696.
    Citations: 111     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  46. Lewis GD, Asnani A, Gerszten RE. Application of metabolomics to cardiovascular biomarker and pathway discovery. J Am Coll Cardiol. 2008 Jul 08; 52(2):117-23. PMID: 18598890; PMCID: PMC3204897.
    Citations: 87     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.