Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Michael Karim Mansour, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI132638 (MANSOUR, MICHAEL K) Aug 16, 2018 - Jul 31, 2022
    The role of spleen tyrosine kinase (syk) in neutrophil responses to pathogenic fungi.
    Role: Principal Investigator
  2. K08AI110655 (MANSOUR, MICHAEL K) Feb 1, 2014 - Jan 31, 2019
    Subcellular Mechanisms for Fungal Phagosome Maturation in Macrophages
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Reedy JL, Crossen AJ, Negoro PE, Harding HB, Ward RA, Vargas-Blanco DA, Timmer KD, Reardon CM, Basham KJ, Mansour MK, Wüthrich M, Fontaine T, Latgé JP, Vyas JM. The C-Type Lectin Receptor Dectin-2 Is a Receptor for Aspergillus fumigatus Galactomannan. mBio. 2023 Jan 04; e0318422. PMID: 36598192.
    Citations:    Fields:    
  2. Miller PG, Fell GG, Foy BH, Scherer AK, Gibson CJ, Sperling AS, Burugula BB, Nakao T, Uddin MM, Warren H, Bry L, Pozdnyakova O, Frigault MJ, Bick AG, Neuberg D, Higgins JM, Mansour MK, Natarajan P, Kim AS, Kitzman JO, Ebert BL. Clonal hematopoiesis of indeterminate potential and risk of death from COVID-19. Blood. 2022 11 03; 140(18):1993-1997. PMID: 36096050; PMCID: PMC9474399.
    Citations:    Fields:    Translation:Humans
  3. Hopke A, Lin T, Scherer AK, Shay AE, Timmer KD, Wilson-Mifsud B, Mansour MK, Serhan CN, Irimia D, Hurley BP. Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi. iScience. 2022 Oct 21; 25(10):105226. PMID: 36267914; PMCID: PMC9576560.
  4. Jusuf S, Zhan Y, Zhang M, Alexander NJ, Viens A, Mansour MK, Cheng JX. Blue Light Deactivation of Catalase Suppresses Candida Hyphae Development Through Lipogenesis Inhibition. Photochem Photobiol. 2022 Sep 19. PMID: 36117418.
    Citations:    Fields:    
  5. Atallah NJ, Panossian VS, Atallah CJ, Schwabe A, Johannes S, Wiemer J, Mansour MK. Mid-regional Proadrenomedullin Biomarker Predicts Coronavirus Disease 2019 Clinical Outcomes: A US-Based Cohort Study. Open Forum Infect Dis. 2022 Sep; 9(9):ofac423. PMID: 36072696; PMCID: PMC9439577.
    Citations: 1     
  6. Atallah CJ, Panossian VS, Atallah NJ, Roberts MB, Mansour MK. Extra-pulmonary applications of procalcitonin: an updated literature review. Expert Rev Mol Diagn. 2022 05; 22(5):537-544. PMID: 35757858.
    Citations:    Fields:    Translation:Humans
  7. Atallah J, Archambault D, Randall JD, Shepro A, Styskal LE, Glenn DR, Connolly CB, Katsis K, Gallagher K, Ghebremichael M, Mansour MK. Rapid Quantum Magnetic IL-6 Point-of-Care Assay in Patients Hospitalized with COVID-19. Diagnostics (Basel). 2022 May 07; 12(5). PMID: 35626318; PMCID: PMC9139897.
  8. Sykes DB, Martinelli MM, Negoro P, Xu S, Maxcy K, Timmer K, Viens AL, Alexander NJ, Atallah J, Snarr BD, Baistrocchi SR, Atallah NJ, Hopke A, Scherer A, Rosales I, Irimia D, Sheppard DC, Mansour MK. Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections. J Leukoc Biol. 2022 06; 111(6):1133-1145. PMID: 35355310; PMCID: PMC9133213.
    Citations:    Fields:    Translation:AnimalsCells
  9. Viens AL, Timmer KD, Alexander NJ, Barghout R, Milosevic J, Hopke A, Atallah NJ, Scherer AK, Sykes DB, Irimia D, Mansour MK. TLR Signaling Rescues Fungicidal Activity in Syk-Deficient Neutrophils. J Immunol. 2022 04 01; 208(7):1664-1674. PMID: 35277418; PMCID: PMC8976732.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Sakuma M, Wang X, Ellett F, Edd JF, Babatunde KA, Viens A, Mansour MK, Irimia D. Microfluidic capture of chromatin fibres measures neutrophil extracellular traps (NETs) released in a drop of human blood. Lab Chip. 2022 03 01; 22(5):936-944. PMID: 35084421; PMCID: PMC8978531.
    Citations:    Fields:    Translation:HumansCells
  11. Rosenberg JM, Villalba JA, Ferrè EMN, Mansour MK, Lionakis MS. A Case Report of Fatal Mucormycosis in a 30-Year-Old Patient with Autoimmune Polyendocrine Syndrome Type 1. J Clin Immunol. 2022 05; 42(4):863-865. PMID: 35141820.
    Citations:    Fields:    Translation:Humans
  12. Dong PT, Zhan Y, Jusuf S, Hui J, Dagher Z, Mansour MK, Cheng JX. Photoinactivation of Catalase Sensitizes Candida albicans and Candida auris to ROS-Producing Agents and Immune Cells. Adv Sci (Weinh). 2022 04; 9(10):e2104384. PMID: 35119220; PMCID: PMC8981478.
    Citations: 1     Fields:    Translation:Animals
  13. Atallah J, Mansour MK. Implications of Using Host Response-Based Molecular Diagnostics on the Management of Bacterial and Viral Infections: A Review. Front Med (Lausanne). 2022; 9:805107. PMID: 35186993; PMCID: PMC8850635.
    Citations: 1     
  14. Atallah NJ, Warren HM, Roberts MB, Elshaboury RH, Bidell MR, Gandhi RG, Adamsick M, Ibrahim MK, Sood R, Bou Zein Eddine S, Cobler-Lichter MJ, Alexander NJ, Timmer KD, Atallah CJ, Viens AL, Panossian VS, Scherer AK, Proctor T, Smartt S, Letourneau AR, Paras ML, Johannes S, Wiemer J, Mansour MK. Baseline procalcitonin as a predictor of bacterial infection and clinical outcomes in COVID-19: A case-control study. PLoS One. 2022; 17(1):e0262342. PMID: 35025929; PMCID: PMC8758006.
    Citations: 2     Fields:    Translation:HumansCells
  15. Ward RA, Aghaeepour N, Bhattacharyya RP, Clish CB, Gaudillière B, Hacohen N, Mansour MK, Mudd PA, Pasupneti S, Presti RM, Rhee EP, Sen P, Spec A, Tam JM, Villani AC, Woolley AE, Hsu JL, Vyas JM. Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease. Open Forum Infect Dis. 2021 Nov; 8(11):ofab483. PMID: 34805429; PMCID: PMC8598922.
  16. Kfoury YS, Ji F, Mazzola M, Sykes DB, Scherer AK, Anselmo A, Akiyama Y, Mercier F, Severe N, Kokkaliaris KD, Zhao T, Brouse T, Saez B, Seidl J, Papazian A, Ivanov P, Mansour MK, Sadreyev RI, Scadden DT. tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche. Cell Stem Cell. 2021 12 02; 28(12):2090-2103.e9. PMID: 34551362; PMCID: PMC8642285.
    Citations: 2     Fields:    Translation:Cells
  17. Barros N, Alexander N, Viens A, Timmer K, Atallah N, Knooihuizen SAI, Hopke A, Scherer A, Dagher Z, Irimia D, Mansour MK. Cytokine Augmentation Reverses Transplant Recipient Neutrophil Dysfunction Against the Human Fungal Pathogen Candida albicans. J Infect Dis. 2021 09 01; 224(5):894-902. PMID: 33417688; PMCID: PMC8577195.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  18. Sundaresh B, Xu S, Noonan B, Mansour MK, Leong JM, van Opijnen T. Host-informed therapies for the treatment of pneumococcal pneumonia. Trends Mol Med. 2021 10; 27(10):971-989. PMID: 34376327.
    Citations: 3     Fields:    Translation:HumansCells
  19. Scherer AK, Hopke A, Sykes DB, Irimia D, Mansour MK. Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities? PLoS Pathog. 2021 07; 17(7):e1009691. PMID: 34324592; PMCID: PMC8321001.
    Citations:    Fields:    Translation:HumansAnimalsCells
  20. Nguyen GT, Xu S, Adams W, Leong JM, Bunnell SC, Mansour MK, Sykes DB, Mecsas J. Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation. iScience. 2021 Aug 20; 24(8):102871. PMID: 34386732; PMCID: PMC8346660.
  21. Meyerowitz EA, Sen P, Schoenfeld SR, Neilan TG, Frigault MJ, Stone JH, Kim AY, Mansour MK. Immunomodulation as Treatment for Severe Coronavirus Disease 2019: A Systematic Review of Current Modalities and Future Directions. Clin Infect Dis. 2021 06 15; 72(12):e1130-e1143. PMID: 33216852; PMCID: PMC7717185.
    Citations: 15     Fields:    Translation:HumansCells
  22. Ward RA, Thompson GR, Villani AC, Li B, Mansour MK, Wuethrich M, Tam JM, Klein BS, Vyas JM. The Known Unknowns of the Immune Response to Coccidioides. J Fungi (Basel). 2021 May 11; 7(5). PMID: 34065016; PMCID: PMC8151481.
    Citations: 1     
  23. Elgendy IY, Kolte D, Mansour MK, Sakhuja R, Elmariah S, Jaffer FA, Neilan TG, Januzzi JL, Weinberg I, Albaghdadi MS. Incidence, Predictors, and Outcomes of Thrombotic Events in Hospitalized Patients With Viral Pneumonia. Am J Cardiol. 2021 03 15; 143:164-165. PMID: 33453170; PMCID: PMC7807171.
    Citations: 1     Fields:    Translation:HumansCells
  24. Dong PT, Zong C, Dagher Z, Hui J, Li J, Zhan Y, Zhang M, Mansour MK, Cheng JX. Polarization-sensitive stimulated Raman scattering imaging resolves amphotericin B orientation in Candida membrane. Sci Adv. 2021 01; 7(2). PMID: 33523971; PMCID: PMC7787481.
    Citations: 7     Fields:    Translation:Animals
  25. Knooihuizen SAI, Alexander NJ, Hopke A, Barros N, Viens A, Scherer A, Atallah NJ, Dagher Z, Irimia D, Chung RT, Mansour MK. Loss of Coordinated Neutrophil Responses to the Human Fungal Pathogen, Candida albicans, in Patients With Cirrhosis. Hepatol Commun. 2021 03; 5(3):502-515. PMID: 33681682; PMCID: PMC7917271.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  26. Meyerowitz EA, Sanchez S, Mansour MK, Triant VA, Goldberg MB. Isolated Cerebral Mucormycosis in Immunocompetent Adults who Inject Drugs: Case Reports and Systematic Review of the Literature. Open Forum Infect Dis. 2020 Dec; 7(12):ofaa552. PMID: 33409328; PMCID: PMC7765436.
    Citations: 2     
  27. Stone JH, Frigault MJ, Serling-Boyd NJ, Fernandes AD, Harvey L, Foulkes AS, Horick NK, Healy BC, Shah R, Bensaci AM, Woolley AE, Nikiforow S, Lin N, Sagar M, Schrager H, Huckins DS, Axelrod M, Pincus MD, Fleisher J, Sacks CA, Dougan M, North CM, Halvorsen YD, Thurber TK, Dagher Z, Scherer A, Wallwork RS, Kim AY, Schoenfeld S, Sen P, Neilan TG, Perugino CA, Unizony SH, Collier DS, Matza MA, Yinh JM, Bowman KA, Meyerowitz E, Zafar A, Drobni ZD, Bolster MB, Kohler M, D'Silva KM, Dau J, Lockwood MM, Cubbison C, Weber BN, Mansour MK. Efficacy of Tocilizumab in Patients Hospitalized with Covid-19. N Engl J Med. 2020 12 10; 383(24):2333-2344. PMID: 33085857; PMCID: PMC7646626.
    Citations: 510     Fields:    Translation:Humans
  28. Mansour MK, Smibert OC, Kambadakone A, Sfeir MM. Case 31-2020: A 48-Year-Old Man with Lymphoma and Abdominal Pain. N Engl J Med. 2020 Oct 08; 383(15):1469-1477. PMID: 33027573.
    Citations:    Fields:    Translation:HumansAnimals
  29. Alexander NJ, Bozym DJ, Farmer JR, Parris P, Viens A, Atallah N, Hopke A, Scherer A, Dagher Z, Barros N, Knooihuizen SAI, Saff RR, Pasternack MS, Thompson RW, Irimia D, Mansour MK. Neutrophil functional profiling and cytokine augmentation for patients with multiple recurrent infections: A case study. J Allergy Clin Immunol Pract. 2021 02; 9(2):986-988. PMID: 32853820; PMCID: PMC7870511.
    Citations: 3     Fields:    Translation:HumansCells
  30. Grover S, Bond SA, Mansour MK, Friedman S. Management of immunotherapy colitis: Special considerations in the COVID-19 era. Cancer. 2020 11 01; 126(21):4630-4633. PMID: 32797685; PMCID: PMC7461305.
    Citations: 2     Fields:    Translation:Humans
  31. Frigault MJ, Nikiforow S, Mansour MK, Hu ZH, Horowitz MM, Riches ML, Hematti P, Turtle CJ, Zhang MJ, Perales MA, Pasquini MC. Tocilizumab not associated with increased infection risk after CAR T-cell therapy: implications for COVID-19? Blood. 2020 07 02; 136(1):137-139. PMID: 32457999; PMCID: PMC7332891.
    Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
  32. Armstrong KA, Cohen JV, Shepard JO, Folch EE, Mansour MK, Stefely JA. Case 16-2020: A 47-Year-Old Woman with Recurrent Melanoma and Pulmonary Nodules. N Engl J Med. 2020 May 21; 382(21):2034-2043. PMID: 32433841.
    Citations: 1     Fields:    Translation:HumansAnimals
  33. Hopke A, Scherer A, Kreuzburg S, Abers MS, Zerbe CS, Dinauer MC, Mansour MK, Irimia D. Publisher Correction: Neutrophil swarming delays the growth of clusters of pathogenic fungi. Nat Commun. 2020 05 14; 11(1):2492. PMID: 32409681.
    Citations:    Fields:    
  34. Negoro PE, Xu S, Dagher Z, Hopke A, Reedy JL, Feldman MB, Khan NS, Viens AL, Alexander NJ, Atallah NJ, Scherer AK, Dutko RA, Jeffery J, Kernien JF, Fites JS, Nett JE, Klein BS, Vyas JM, Irimia D, Sykes DB, Mansour MK. Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species. mBio. 2020 05 12; 11(3). PMID: 32398316; PMCID: PMC7218286.
    Citations: 12     Fields:    Translation:AnimalsCells
  35. Hopke A, Scherer A, Kreuzburg S, Abers MS, Zerbe CS, Dinauer MC, Mansour MK, Irimia D. Neutrophil swarming delays the growth of clusters of pathogenic fungi. Nat Commun. 2020 04 27; 11(1):2031. PMID: 32341348.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  36. Atallah NJ, Scherer AK, Alexander NJ, Dagher Z, Viens AL, Muhammed M, Branda JA, Mansour MK. Candida albicans necrotizing fasciitis following elective surgery. Med Mycol Case Rep. 2020 Jun; 28:39-41. PMID: 32420013; PMCID: PMC7214761.
    Citations: 1     
  37. Reynolds KL, Sullivan RJ, Fintelmann FJ, Mansour MK, England J. Case 9-2020: A 64-Year-Old Man with Shortness of Breath, Cough, and Hypoxemia. N Engl J Med. 2020 Mar 19; 382(12):1150-1159. PMID: 32187473.
    Citations: 1     Fields:    Translation:Humans
  38. DeFilipp Z, Bloom PP, Torres Soto M, Mansour MK, Sater MRA, Huntley MH, Turbett S, Chung RT, Chen YB, Hohmann EL. Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant. N Engl J Med. 2019 11 21; 381(21):2043-2050. PMID: 31665575.
    Citations: 250     Fields:    Translation:HumansCells
  39. Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM. CD82 controls CpG-dependent TLR9 signaling. FASEB J. 2019 11; 33(11):12500-12514. PMID: 31408613; PMCID: PMC6988855.
    Citations: 6     Fields:    Translation:AnimalsCells
  40. Mewes JC, Pulia MS, Mansour MK, Broyles MR, Nguyen HB, Steuten LM. The cost impact of PCT-guided antibiotic stewardship versus usual care for hospitalised patients with suspected sepsis or lower respiratory tract infections in the US: A health economic model analysis. PLoS One. 2019; 14(4):e0214222. PMID: 31013271; PMCID: PMC6478294.
    Citations: 12     Fields:    Translation:Humans
  41. Tam JM, Reedy JL, Lukason DP, Kuna SG, Acharya M, Khan NS, Negoro PE, Xu S, Ward RA, Feldman MB, Dutko RA, Jeffery JB, Sokolovska A, Wivagg CN, Lassen KG, Le Naour F, Matzaraki V, Garner EC, Xavier RJ, Kumar V, van de Veerdonk FL, Netea MG, Miranti CK, Mansour MK, Vyas JM. Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans. J Immunol. 2019 06 01; 202(11):3256-3266. PMID: 31010852; PMCID: PMC6529278.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  42. Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Hoggatt J, Saez B, Pang WW, Mansour MK, Tate TA, Chan YY, Walck E, Wernig G, Shizuru JA, Winau F, Scadden DT, Rossi DJ. Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation. Nat Commun. 2019 02 06; 10(1):617. PMID: 30728354.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  43. Adamsick ML, Elshaboury RH, Gift T, Mansour MK, Kotton CN, Gandhi RG. Therapeutic drug concentrations of isavuconazole following the administration of isavuconazonium sulfate capsules via gastro-jejunum tube: A case report. Transpl Infect Dis. 2019 Apr; 21(2):e13048. PMID: 30636363.
    Citations: 6     Fields:    Translation:Humans
  44. Kugadas A, Geddes-McAlister J, Guy E, DiGiandomenico A, Sykes DB, Mansour MK, Mirchev R, Gadjeva M. Frontline Science: Employing enzymatic treatment options for management of ocular biofilm-based infections. J Leukoc Biol. 2019 06; 105(6):1099-1110. PMID: 30690787.
    Citations: 10     Fields:    Translation:AnimalsCells
  45. Lane RJ, Kradin R, Xia D, Buchan CA, Turbett S, Kotton CN, Mansour MK. Malakoplakia in Thoracic Transplant Recipients. Transplant Proc. 2019 Apr; 51(3):871-874. PMID: 30979478; PMCID: PMC6464378.
    Citations:    Fields:    Translation:Humans
  46. Mamouei Z, Alqarihi A, Singh S, Xu S, Mansour MK, Ibrahim AS, Uppuluri P. Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens. mSphere. 2018 10 31; 3(5). PMID: 30381356.
    Citations: 12     Fields:    Translation:Animals
  47. Vyas JM, Rajagopal J, Sokol CL, Wein MN, Mansour MK, Corey KE, Fishman MC, Armstrong KA. The Great Opportunity: Cultivating Scientific Inquiry in Medical Residency. J Infect Dis. 2018 08 14; 218(suppl_1):S44-S48. PMID: 29878132; PMCID: PMC6093444.
    Citations: 1     Fields:    Translation:Humans
  48. Feldman MB, Vyas JM, Mansour MK. It takes a village: Phagocytes play a central role in fungal immunity. Semin Cell Dev Biol. 2019 05; 89:16-23. PMID: 29727727; PMCID: PMC6235731.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  49. Simmonds JC, Mansour MK, Dagher WI. Cervical Lymphatic Filariasis in a Pediatric Patient: Case Report and Database Analysis of Lymphatic Filariasis in the United States. Am J Trop Med Hyg. 2018 07; 99(1):104-111. PMID: 29848402; PMCID: PMC6085779.
    Citations:    Fields:    Translation:HumansAnimals
  50. Fites JS, Gui M, Kernien JF, Negoro P, Dagher Z, Sykes DB, Nett JE, Mansour MK, Klein BS. An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections. PLoS Pathog. 2018 05; 14(5):e1007073. PMID: 29782541; PMCID: PMC5983859.
    Citations: 29     Fields:    Translation:AnimalsCells
  51. Dagher Z, Xu S, Negoro PE, Khan NS, Feldman MB, Reedy JL, Tam JM, Sykes DB, Mansour MK. Fluorescent Tracking of Yeast Division Clarifies the Essential Role of Spleen Tyrosine Kinase in the Intracellular Control of Candida glabrata in Macrophages. Front Immunol. 2018; 9:1058. PMID: 29868018; PMCID: PMC5964189.
    Citations: 4     Fields:    Translation:AnimalsCells
  52. DeFilipp Z, Peled JU, Li S, Mahabamunuge J, Dagher Z, Slingerland AE, Del Rio C, Valles B, Kempner ME, Smith M, Brown J, Dey BR, El-Jawahri A, McAfee SL, Spitzer TR, Ballen KK, Sung AD, Dalton TE, Messina JA, Dettmer K, Liebisch G, Oefner P, Taur Y, Pamer EG, Holler E, Mansour MK, van den Brink MRM, Hohmann E, Jenq RR, Chen YB. Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity. Blood Adv. 2018 04 10; 2(7):745-753. PMID: 29592876.
    Citations: 83     Fields:    Translation:HumansCTClinical Trials
  53. Li SS, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, Robbins SM, Mody CH. Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida. Nat Commun. 2018 02 21; 9(1):751. PMID: 29467448.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  54. Xu S, Feliu M, Lord AK, Lukason DP, Negoro PE, Khan NS, Dagher Z, Feldman MB, Reedy JL, Steiger SN, Tam JM, Soukas AA, Sykes DB, Mansour MK. Biguanides enhance antifungal activity against Candida glabrata. Virulence. 2018; 9(1):1150-1162. PMID: 29962263; PMCID: PMC6086317.
    Citations: 7     Fields:    Translation:HumansAnimals
  55. Mansour MK, Letourneau AR, Wallace ZS, Fintelmann FJ, Foreman RK. Case 15-2017 - A 27-Year-Old Woman with Anemia, Thrombocytosis, and Skin Lesions after Travel Abroad. N Engl J Med. 2017 May 18; 376(20):1973-1981. PMID: 28514603.
    Citations: 1     Fields:    Translation:Humans
  56. Reedy JL, Negoro PE, Feliu M, Lord AK, Khan NS, Lukason DP, Wiederhold NP, Tam JM, Mansour MK, Patterson TF, Vyas JM. The Carbohydrate Lectin Receptor Dectin-1 Mediates the Immune Response to Exserohilum rostratum. Infect Immun. 2017 03; 85(3). PMID: 28031265; PMCID: PMC5328484.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  57. McCluskey SM, Schuetz P, Abers MS, Bearnot B, Morales ME, Hoffman D, Patel S, Rosario L, Chiappa V, Parry BA, Callahan RT, Bond SA, Lewandrowski K, Binder W, Filbin MR, Vyas JM, Mansour MK. Serial Procalcitonin as a Predictor of Bacteremia and Need for Intensive Care Unit Care in Adults With Pneumonia, Including Those With Highest Severity: A Prospective Cohort Study. Open Forum Infect Dis. 2017; 4(1):ofw238. PMID: 28480236; PMCID: PMC5414101.
    Citations: 3     
  58. Al-Mozaini MA, Mansour MK. Personalized medicine. Is it time for infectious diseases? Saudi Med J. 2016 Dec; 37(12):1309-1311. PMID: 27874145.
    Citations: 3     Fields:    Translation:Humans
  59. Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nat Biotechnol. 2016 07; 34(7):738-45. PMID: 27272386; PMCID: PMC5179034.
    Citations: 86     Fields:    Translation:AnimalsCells
  60. Turbett SE, Mansour MK. Editorial Commentary: Fecal ESBL Screening: Are We Ready for This Information? Clin Infect Dis. 2016 08 01; 63(3):319-21. PMID: 27143673; PMCID: PMC4946017.
    Citations: 3     Fields:    Translation:HumansCells
  61. Tam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM. The Role of Autophagy-Related Proteins in Candida albicans Infections. Pathogens. 2016 Mar 29; 5(2). PMID: 27043636; PMCID: PMC4931385.
    Citations: 6     
  62. Li X, Cullere X, Nishi H, Saggu G, Durand E, Mansour MK, Tam JM, Song XY, Lin X, Vyas JM, Mayadas T. PKC-d activation in neutrophils promotes fungal clearance. J Leukoc Biol. 2016 09; 100(3):581-8. PMID: 26965632; PMCID: PMC6608027.
    Citations: 11     Fields:    Translation:AnimalsCells
  63. Khan NS, Kasperkovitz PV, Timmons AK, Mansour MK, Tam JM, Seward MW, Reedy JL, Puranam S, Feliu M, Vyas JM. Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing ß-1,3 Glucan. J Immunol. 2016 Mar 01; 196(5):2249-61. PMID: 26829985; PMCID: PMC4761466.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  64. Mansour MK, Ackman JB, Branda JA, Kradin RL. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 32-2015. A 57-Year-Old Man with Severe Pneumonia and Hypoxemic Respiratory Failure. N Engl J Med. 2015 Oct 15; 373(16):1554-64. PMID: 26465989.
    Citations: 2     Fields:    Translation:HumansAnimals
  65. Khajuria RK, Blankenburg F, Wuithschick I, Rueckriegel S, Thomale UW, Mansour M, Driever PH. Morphological brain lesions of pediatric cerebellar tumor survivors correlate with inferior neurocognitive function but do not affect health-related quality of life. Childs Nerv Syst. 2015 Apr; 31(4):569-80. PMID: 25686892.
    Citations: 5     Fields:    Translation:Humans
  66. Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Tam JM, Vyas JM, Slevogt H. Erratum to: Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes. Med Microbiol Immunol. 2014 Dec; 203(6):425. PMID: 25298302.
  67. Al-Mozaini MA, Mansour MK, Al-Hokail AA, Mohmed MA, Daham MA, Al-Abdely HM, Frayha HH, Al-Rabiah FA, Alhajjar SH, Keshavjee S, Adra CN, Alrajhi AA. HIV-Care Outcome in Saudi Arabia; a Longitudinal Cohort. J AIDS Clin Res. 2014 Nov 08; 5(11). PMID: 25750760; PMCID: PMC4350238.
    Citations: 4     
  68. Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Mansour MM, Tam JM, Vyas JM, Slevogt H. Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes. Med Microbiol Immunol. 2014 Dec; 203(6):415-24. PMID: 25129478.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  69. Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM. Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages. J Infect Dis. 2014 Dec 01; 210(11):1844-54. PMID: 24842831; PMCID: PMC4271056.
    Citations: 53     Fields:    Translation:AnimalsCells
  70. Kasper L, Seider K, Gerwien F, Allert S, Brunke S, Schwarzmüller T, Ames L, Zubiria-Barrera C, Mansour MK, Becken U, Barz D, Vyas JM, Reiling N, Haas A, Haynes K, Kuchler K, Hube B. Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages. PLoS One. 2014; 9(5):e96015. PMID: 24789333; PMCID: PMC4006850.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  71. Mansour MK, Reedy JL, Tam JM, Vyas JM. Macrophage Cryptococcus interactions: an update. Curr Fungal Infect Rep. 2014 Mar 01; 8(1):109-115. PMID: 24660045.
    Citations: 10     
  72. Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM. Dectin-1 activation controls maturation of ß-1,3-glucan-containing phagosomes. J Biol Chem. 2013 May 31; 288(22):16043-54. PMID: 23609446.
    Citations: 37     Fields:    Translation:AnimalsCells
  73. Grimm MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan AN, D'Auria AC, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Röhm M, Urban CF, Kelkka T, Holmdahl R, Segal BH. Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. J Immunol. 2013 Apr 15; 190(8):4175-84. PMID: 23509361; PMCID: PMC3622122.
    Citations: 38     Fields:    Translation:AnimalsCells
  74. Mitsuma SF, Mansour MK, Dekker JP, Kim J, Rahman MZ, Tweed-Kent A, Schuetz P. Promising new assays and technologies for the diagnosis and management of infectious diseases. Clin Infect Dis. 2013 Apr; 56(7):996-1002. PMID: 23223587.
    Citations: 17     Fields:    Translation:Humans
  75. Mansour MK, Tam JM, Vyas JM. The cell biology of the innate immune response to Aspergillus fumigatus. Ann N Y Acad Sci. 2012 Dec; 1273:78-84. PMID: 23230841.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  76. Tam JM, Mansour MK, Khan NS, Yoder NC, Vyas JM. Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity. Integr Biol (Camb). 2012 Feb; 4(2):220-7. PMID: 22200052.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  77. Mansour MK, Vyas JM, Levitz SM. Dynamic virulence: real-time assessment of intracellular pathogenesis links Cryptococcus neoformans phenotype with clinical outcome. mBio. 2011; 2(5). PMID: 21954307.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  78. Kasperkovitz PV, Khan NS, Tam JM, Mansour MK, Davids PJ, Vyas JM. Toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of Candida albicans and Saccharomyces cerevisiae. Infect Immun. 2011 Dec; 79(12):4858-67. PMID: 21947771.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  79. Tam JM, Castro CE, Heath RJ, Mansour MK, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM. Use of an optical trap for study of host-pathogen interactions for dynamic live cell imaging. J Vis Exp. 2011 Jul 28; (53). PMID: 21841755.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  80. Streibert PF, Piroth W, Mansour M, Haage P, Langer T, Borusiak P. Magnetic resonance imaging of the brain in children with headache: the clinical relevance with modern acquisition techniques. Clin Pediatr (Phila). 2011 Dec; 50(12):1134-9. PMID: 21757775.
    Citations: 2     Fields:    Translation:Humans
  81. Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, et al. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7. PMID: 21051598; PMCID: PMC3235490.
    Citations: 654     Fields:    Translation:HumansCells
  82. Mansour MK, Latz E, and Levitz SM. Cryptococcus neoformans Mannoprotein Are Captured by Multiple Lectin Receptors and Exclusively Presented by Dendritic Cells. Journal of Immunology. 2006; 176(5):3053-61.
  83. Mansour MK, Latz E, Levitz SM. Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells. J Immunol. 2006 Mar 01; 176(5):3053-61. PMID: 16493064.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  84. Lam J, Mansour MK, Specht C, and Levitz SM. A model vaccine exploiting fungal mannosylation to increase antigen immunogenicity. Journal of Immunology. 2005; 175(11):7496-503.
  85. Lam JS, Mansour MK, Specht CA, Levitz SM. A model vaccine exploiting fungal mannosylation to increase antigen immunogenicity. J Immunol. 2005 Dec 01; 175(11):7496-503. PMID: 16301657.
    Citations: 34     Fields:    Translation:AnimalsCells
  86. Yauch LE, Mansour MK, Levitz SM. Receptor-mediated clearance of Cryptococcus neoformans capsular polysaccharide in vivo. Infect Immun. 2005 Dec; 73(12):8429-32. PMID: 16299344; PMCID: PMC1307074.
    Citations: 23     Fields:    Translation:Animals
  87. Mansour MK. Host Response to the Mannosylated Antigens from the Pathogenic Yeast, Cryptococcus neoformans. 2005.
  88. Herrero AB, Magnelli P, Mansour MK, Levitz SM, Bussey H, Abeijon C. KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties. Eukaryot Cell. 2004 Dec; 3(6):1423-32. PMID: 15590817; PMCID: PMC539026.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  89. Yauch LE, Mansour MK, Shoham S, Rottman JB, Levitz SM. Involvement of CD14, toll-like receptors 2 and 4, and MyD88 in the host response to the fungal pathogen Cryptococcus neoformans in vivo. Infect Immun. 2004 Sep; 72(9):5373-82. PMID: 15322035; PMCID: PMC517466.
    Citations: 67     Fields:    Translation:Animals
  90. Mansour MK, Yauch LE, Rottman JB, Levitz SM. Protective efficacy of antigenic fractions in mouse models of cryptococcosis. Infect Immun. 2004 Mar; 72(3):1746-54. PMID: 14977983.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  91. Mansour MK and Levitz SM. Fungal Mannoprotein: The Sweet Path to Immunodominance. ASM News. 2003; 69(12):595-600.
  92. Mansour MK and Levitz SM. Methods and Compositions for Eliciting Immune Responses Using Mannosylated-Antigen Fusion Delivery. 2002.
  93. Huang C, Nong SH, Mansour MK, Specht CA, Levitz SM. Purification and characterization of a second immunoreactive mannoprotein from Cryptococcus neoformans that stimulates T-Cell responses. Infect Immun. 2002 Oct; 70(10):5485-93. PMID: 12228274.
    Citations: 39     Fields:    Translation:AnimalsCells
  94. Mansour MK, Levitz SM. Interactions of fungi with phagocytes. Curr Opin Microbiol. 2002 Aug; 5(4):359-65. PMID: 12160853.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  95. Mansour MK, Schlesinger LS, Levitz SM. Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors. J Immunol. 2002 Mar 15; 168(6):2872-9. PMID: 11884457.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  96. Mansour MK, Schelsinger LS, Levitz SM. Optimal T-cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors. Journal of Immunology. 2002; 168(6):2872-2879.
  97. Levitz SM, Nong S, Mansour MK, Huang C, Specht CA. Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10422-7. PMID: 11504924; PMCID: PMC56976.
    Citations: 60     Fields:    Translation:AnimalsCells
  98. Rand ML, Warren JS, Mansour MK, Newman W, Ringler DJ. Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1. Am J Pathol. 1996 Mar; 148(3):855-64. PMID: 8774140; PMCID: PMC1861724.
    Citations: 15     Fields:    Translation:AnimalsCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Mansour's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (446)
Co-Authors (135)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.