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Shahzad Shaefi, M.B.,B.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Subramaniam B, Shankar P, Shaefi S, Mueller A, O'Gara B, Banner-Goodspeed V, Gallagher J, Gasangwa D, Patxot M, Packiasabapathy S, Mathur P, Eikermann M, Talmor D, Marcantonio ER. Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial. JAMA. 2019 02 19; 321(7):686-696. PMID: 30778597.
    Citations:    
  2. Packiasabapathy S, Susheela AT, Mueller A, Patxot M, Gasangwa DV, O'Gara B, Shaefi S, Marcantonio ER, Yeh GY, Subramaniam B. Guided meditation as an adjunct to enhance postoperative recovery after cardiac surgery: study protocol for a prospective randomized controlled feasibility trial. Trials. 2019 Jan 11; 20(1):39. PMID: 30635064.
    Citations:    Fields:    
  3. Rostin P, Teja BJ, Friedrich S, Shaefi S, Murugappan KR, Ramachandran SK, Houle TT, Eikermann M. The association of early postoperative desaturation in the operating theatre with hospital discharge to a skilled nursing or long-term care facility. Anaesthesia. 2019 Apr; 74(4):457-467. PMID: 30632138.
    Citations:    Fields:    
  4. O'Gara B, Marcantonio ER, Pascual-Leone A, Shaefi S, Mueller A, Banner-Goodspeed V, Talmor D, Subramaniam B. Prevention of Early Postoperative Decline (PEaPoD): protocol for a randomized, controlled feasibility trial. Trials. 2018 Dec 11; 19(1):676. PMID: 30537982.
    Citations:    Fields:    
  5. Evans AS, Weiner M, Jain A, Patel PA, Jayaraman AL, Townsley MM, Shah R, Gutsche JT, Renew JR, Ha B, Martin AK, Linganna R, Leong R, Bhatt HV, Garcia H, Feduska E, Shaefi S, Feinman JW, Eden C, Weiss SJ, Silvay G, Augoustides JG, Ramakrishna H. The Year in Cardiothoracic and Vascular Anesthesia: Selected Highlights from 2018. J Cardiothorac Vasc Anesth. 2019 Jan; 33(1):2-11. PMID: 30472017.
    Citations:    Fields:    
  6. Loberman D, Shaefi S, Mohr R, Dombrowski P, Zelman RB, Zheng Y, Pirundini PA, Ziv-Baran T. Trans-catheter aortic valve replacement program in a community hospital - Comparison with US national data. PLoS One. 2018; 13(9):e0204766. PMID: 30261048.
    Citations:    Fields:    
  7. Cormican D, Jayaraman AL, Sheu R, Peterson C, Narasimhan S, Shaefi S, Gil IJN, Ramakrishna H. Coronary Artery Bypass Grafting Versus Percutaneous Transcatheter Coronary Interventions: Analysis of Outcomes in Myocardial Revascularization. J Cardiothorac Vasc Anesth. 2018 Sep 20. PMID: 30340948.
    Citations:    Fields:    
  8. Murugappan KR, Cocchi MN, Bose S, Neves SE, Cook CH, Sarge T, Shaefi S, Leibowitz A. Case Study: Fatal Exertional Rhabdomyolysis Possibly Related to Drastic Weight Cutting. Int J Sport Nutr Exerc Metab. 2018 Sep 11; 1-4. PMID: 29893586.
    Citations:    Fields:    
  9. Shankar P, Mueller A, Packiasabapathy S, Gasangwa D, Patxot M, O'Gara B, Shaefi S, Marcantonio ER, Subramaniam B. Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial. Trials. 2018 Jun 22; 19(1):326. PMID: 29929533.
    Citations:    Fields:    
  10. Shelton KT, Qu J, Bilotta F, Brown EN, Cudemus G, D'Alessandro DA, Deng H, DiBiasio A, Gitlin JA, Hahm EY, Hobbs LE, Houle TT, Ibala R, Loggia ML, Pavone KJ, Shaefi S, Tolis G, Westover MB, Akeju O. Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial. BMJ Open. 2018 04 20; 8(4):e020316. PMID: 29678977.
    Citations: 1     Fields:    Translation:Humans
  11. Shaefi S, Mittel A, Loberman D, Ramakrishna H. Off-Pump Versus On-Pump Coronary Artery Bypass Grafting-A Systematic Review and Analysis of Clinical Outcomes. J Cardiothorac Vasc Anesth. 2019 Jan; 33(1):232-244. PMID: 29753665.
    Citations:    Fields:    
  12. Patlak J, Shaefi S, Buhl L, Boone MD. Neurocritical Care Needs Predictive Scores That Succeed at Predicting Failure as Well as They Predict Success. Anesthesiology. 2018 Mar; 128(3):686-687. PMID: 29438255.
    Citations:    Fields:    
  13. Shaefi S, Eikermann M. Analysing tidal volumes early after a positive end-expiratory pressure increase: a new way to determine optimal PEEP in the operating theatre? Br J Anaesth. 2018 04; 120(4):623-626. PMID: 29576103.
    Citations:    Fields:    
  14. Shankar P, Robson SC, Otterbein LE, Shaefi S. Clinical Implications of Hyperoxia. Int Anesthesiol Clin. 2018; 56(1):68-79. PMID: 29227312.
    Citations:    Fields:    
  15. Shaefi S, Marcantonio ER, Mueller A, Banner-Goodspeed V, Robson SC, Spear K, Otterbein LE, O'Gara BP, Talmor DS, Subramaniam B. Intraoperative oxygen concentration and neurocognition after cardiac surgery: study protocol for a randomized controlled trial. Trials. 2017 Dec 19; 18(1):600. PMID: 29254495.
    Citations:    Fields:    Translation:Humans
  16. Shaefi S, Mittel A, Klick J, Evans A, Ivascu NS, Gutsche J, Augoustides JGT. Vasoplegia After Cardiovascular Procedures-Pathophysiology and Targeted Therapy. J Cardiothorac Vasc Anesth. 2018 04; 32(2):1013-1022. PMID: 29223724.
    Citations:    Fields:    Translation:Humans
  17. Bagchi A, Rudolph MI, Ng PY, Timm FP, Long DR, Shaefi S, Ladha K, Vidal Melo MF, Eikermann M. The association of postoperative pulmonary complications in 109,360 patients with pressure-controlled or volume-controlled ventilation. Anaesthesia. 2017 Nov; 72(11):1334-1343. PMID: 28891046.
    Citations: 2     Fields:    
  18. Amir R, Knio ZO, Mahmood F, Oren-Grinberg A, Leibowitz A, Bose R, Shaefi S, Mitchell JD, Ahmed M, Bardia A, Talmor D, Matyal R. Ultrasound as a Screening Tool for Central Venous Catheter Positioning and Exclusion of Pneumothorax. Crit Care Med. 2017 Jul; 45(7):1192-1198. PMID: 28422778.
    Citations: 1     Fields:    Translation:Humans
  19. Boone MD, Jinadasa SP, Mueller A, Shaefi S, Kasper EM, Hanafy KA, O'Gara BP, Talmor DS. The Effect of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Hemodynamics. Neurocrit Care. 2017 04; 26(2):174-181. PMID: 27848125.
    Citations: 3     Fields:    Translation:Humans
  20. Amir R, Knio Z, Mahmood F, Oren-Grinberg A, Leibowitz A, Shaefi S, Mitchell J, Matyal R. 1103: ULTRASOUND AS A SCREENING TOOL FOR CENTRAL VENOUS CATHETER POSITIONING AND EXCLUSION OF PNEUMOTHORAX. Crit Care Med. 2016 Dec; 44(12 Suppl 1):351. PMID: 27850740.
    Citations:    
  21. Patlak J, Bose S, Shankar P, Shaefi S. 1622: MECHANICAL MITRAL VALVE THROMBOSIS PRESENTING AS SEPTIC SHOCK. Crit Care Med. 2016 Dec; 44(12 Suppl 1):481. PMID: 27851257.
    Citations:    
  22. Shaefi S, Mueller A, Banner-Goodspeed V, Shahul S, Sarge T, Sevransky J, Talmor D. 937: PREVALENCE AND OUTCOMES OF HYPEROXIA IN THE INTENSIVE CARE UNIT. Crit Care Med. 2016 Dec; 44(12 Suppl 1):310. PMID: 27850575.
    Citations:    
  23. Katsios C, Doumouras A, Shaefi S, Novack V, Talmor D. 22: CONSERVATIVE FLUID STRATEGIES DECREASE MORTALITY IN SEPSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. Crit Care Med. 2016 Dec; 44(12 Suppl 1):92. PMID: 27849702.
    Citations:    
  24. Shaefi S, Mittel AM, Hyam JA, Boone MD, Chen CC, Kasper EM. Hypothermia for severe traumatic brain injury in adults: Recent lessons from randomized controlled trials. Surg Neurol Int. 2016; 7:103. PMID: 28168089.
    Citations: 1     
  25. Nizamuddin J, Mahmood F, Tung A, Mueller A, Brown SM, Shaefi S, O'Connor M, Talmor D, Shahul S. Interval Changes in Myocardial Performance Index Predict Outcome in Severe Sepsis. J Cardiothorac Vasc Anesth. 2017 Jun; 31(3):957-964. PMID: 28094172.
    Citations: 1     Fields:    Translation:Humans
  26. Ramakrishna H, Gutsche JT, Patel PA, Evans AS, Weiner M, Morozowich ST, Gordon EK, Riha H, Bracker J, Ghadimi K, Murphy S, Spitz W, MacKay E, Cios TJ, Malhotra AK, Baron E, Shaefi S, Fassl J, Weiss SJ, Silvay G, Augoustides JG. The Year in Cardiothoracic and Vascular Anesthesia: Selected Highlights From 2016. J Cardiothorac Vasc Anesth. 2017 02; 31(1):1-13. PMID: 28041810.
    Citations: 1     Fields:    
  27. Shaefi S, Talmor DS, Subramaniam B. Oxygen Therapy: When Is Too Much Too Much? Anesthesiology. 2016 09; 125(3):449-50. PMID: 27404220.
    Citations: 1     Fields:    Translation:Humans
  28. Shahul S, Tung A, Minhaj M, Nizamuddin J, Wenger J, Mahmood E, Mueller A, Shaefi S, Scavone B, Kociol RD, Talmor D, Rana S. Racial Disparities in Comorbidities, Complications, and Maternal and Fetal Outcomes in Women With Preeclampsia/eclampsia. Hypertens Pregnancy. 2015 Nov; 34(4):506-515. PMID: 26636247.
    Citations: 2     Fields:    
  29. Shaefi S, O'Gara B, Kociol RD, Joynt K, Mueller A, Nizamuddin J, Mahmood E, Talmor D, Shahul S. Effect of cardiogenic shock hospital volume on mortality in patients with cardiogenic shock. J Am Heart Assoc. 2015 Jan 05; 4(1):e001462. PMID: 25559014.
    Citations: 4     Fields:    Translation:Humans
  30. Shahul S, Hacker MR, Novack V, Mueller A, Shaefi S, Mahmood B, Ali SH, Talmor D. The effect of hospital volume on mortality in patients admitted with severe sepsis. PLoS One. 2014; 9(9):e108754. PMID: 25264788.
    Citations: 2     Fields:    Translation:Humans
  31. José RJ, Shaefi S, Navani N. Anesthesia for bronchoscopy. Curr Opin Anaesthesiol. 2014 Aug; 27(4):453-7. PMID: 24785119.
    Citations: 7     Fields:    Translation:Humans
  32. Beitler JR, Shaefi S, Montesi SB, Devlin A, Loring SH, Talmor D, Malhotra A. Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis. Intensive Care Med. 2014 Mar; 40(3):332-41. PMID: 24435203.
    Citations: 23     Fields:    Translation:Humans
  33. Odom SR, Shaefi S, Gupta A, Reed AJ. The seventh patient. Am J Respir Crit Care Med. 2013 Jul 15; 188(2):131-2. PMID: 23855690.
    Citations:    Fields:    Translation:Humans
  34. José RJ, Shaefi S, Navani N. Sedation for flexible bronchoscopy: current and emerging evidence. Eur Respir Rev. 2013 Jun 01; 22(128):106-16. PMID: 23728864.
    Citations: 16     Fields:    Translation:Humans
  35. Malhotra G, Elkassabany NM, Frogel J, Patel AR, Steinberg G, Shaefi S, Mahmood F. CASE 8--2012 intraoperative embolization of renal cell tumor thrombus during radical nephrectomy. J Cardiothorac Vasc Anesth. 2012 Dec; 26(6):1124-30. PMID: 22883446.
    Citations:    Fields:    Translation:Humans
  36. Coleman MD, Shaefi S, Sladen RN. Preventing acute kidney injury after cardiac surgery. Curr Opin Anaesthesiol. 2011 Feb; 24(1):70-6. PMID: 21157303.
    Citations: 17     Fields:    Translation:Humans
  37. Khawaja OM, Reed JT, Shaefi S, Chitilian HV, Sandberg WS. Crisis resource management of the airway in a patient with Klippel-Feil syndrome, congenital deafness, and aortic dissection. Anesth Analg. 2009 Apr; 108(4):1220-5. PMID: 19299791.
    Citations: 2     Fields:    Translation:Humans
  38. Bateman BT, Schumacher HC, Wang S, Shaefi S, Berman MF. Perioperative acute ischemic stroke in noncardiac and nonvascular surgery: incidence, risk factors, and outcomes. Anesthesiology. 2009 Feb; 110(2):231-8. PMID: 19194149.
    Citations: 34     Fields:    Translation:Humans
  39. Newman S, Stygall J, Hirani S, Shaefi S, Maze M. Postoperative cognitive dysfunction after noncardiac surgery: a systematic review. Anesthesiology. 2007 Mar; 106(3):572-90. PMID: 17325517.
    Citations: 104     Fields:    Translation:Humans
  40. Hirani SP, Hyam JA, Shaefi S, Walker JM, Walesby RK, Newman SP. An examination of factors influencing the choice of therapy for patients with coronary artery disease. BMC Cardiovasc Disord. 2006 Jul 04; 6:31. PMID: 16820053.
    Citations:    Fields:    Translation:Humans
  41. Bennett-Guerrero E, Hyam JA, Shaefi S, Prytherch DR, Sutton GL, Weaver PC, Mythen MG, Grocott MP, Parides MK. Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK. Br J Surg. 2003 Dec; 90(12):1593-8. PMID: 14648741.
    Citations: 27     Fields:    Translation:Humans
  42. Shaefi S, Harkness W. Current status of surgery in the management of epilepsy. Epilepsia. 2003; 44 Suppl 1:43-7. PMID: 12558832.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.