Christopher Joseph O'Donnell, M.D.
|Title||Associate Professor of Medicine, Part-time|
|Institution||Brigham and Women's Hospital|
|Address||National Heart, Lung and Blood Inst|
Framingham Heart Study, #2
73 Mount Wayte Ave
Framingham MA 01702
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Available: 07/01/17, Expires: 08/31/19
Dr. O’Donnell conducts his research through his role as Chief Scientist of the Veteran's Administration Million Veteran Program, a mega-biobank that has enrolled over 500,000 Veteran participants with extensive genotype and DNA sequence and clinical phenotype data. He is also a senior investigator associated with the National Heart, Lung and Blood Institute's Framingham Heart Study, in which detailed clinical phenotyping has been completed and genomewide scans of single nucleotide polymorphisms, exome/whole genome sequencing, transcriptome profiling and RNA sequencing has been completed. In collaboration with multiple other cohorts in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and the Exome Sequencing Program, Dr. O'Donnell directs studies of the genetic determinants of subclinical atherosclerosis, clinical coronary heart disease, thrombosis and hemostasis and coronary heart disease risk factors. He has been director and principal investigator of a large study of multidetector computed tomography imaging in two generations of family members to study coronary and aortic atherosclerosis. He is VA Principle Investigator of the national Precision Medicine Initiative All of Us Program and a Co-Investigator in the American Heart Association One Brave idea Program.
A number of student projects are possible using data from these various projects and programs.
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