Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Thomas J. Spencer, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. U01FD005240 (SPENCER, THOMAS J) Sep 10, 2014 - Aug 31, 2020
    NIH
    Pharmacokinetic Pharmacodynamic Studies of Methylphenidate Extended Release Products in Pediatric Attention Deficit Hyperactivity Disorder
    Role: Principal Investigator
  2. R01MH064019 (SPENCER, THOMAS J) Apr 24, 2003 - Jan 31, 2010
    NIH
    Dopamine Transporter Binding by PET in Adult ADHD
    Role: Principal Investigator
  3. R29MH057511 (SPENCER, THOMAS J) May 1, 1998 - Feb 28, 2003
    NIH
    CONTROLLED STUDY OF METHYLPHENIDATE IN ADULTS WITH ADHD
    Role: Principal Investigator
  4. P51RR000168 (FLIER, JEFFREY S) May 1, 1997 - Apr 30, 2013
    NIH
    New England Primate Research Center Base Grant
    Role: Co-Principal Investigator
  5. K20MH001169 (SPENCER, THOMAS J) May 1, 1994 - Apr 30, 1999
    NIH
    DESIPRAMINE IN CHILDREN AND ADOLESCENTS
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jauhar S, Lai S, Bonoldi I, Salazar de Pablo G, di Forti M, Alameda L, Donocik J, Iacoponi E, Spencer T, Haege B, McLaughlan D, Taylor D, Young AH, Thornicroft G, Gaughran F, MacCabe JH, Murray RM, McGuire P, Fusar-Poli P. Early intervention in psychosis during the COVID-19 pandemic: Maudsley recommendations. Eur Neuropsychopharmacol. 2021 06; 47:130-135. PMID: 33642195.
    Citations:    Fields:    Translation:HumansPHPublic Health
  2. Zhang L, McCarthy DM, Eskow Jaunarajs KL, Biederman J, Spencer TJ, Bhide PG. Frontal Cortical Monoamine Release, Attention, and Working Memory in a Perinatal Nicotine Exposure Mouse Model Following Kappa Opioid Receptor Antagonism. Cereb Cortex. 2021 01 01; 31(1):483-496. PMID: 32869057.
    Citations:    Fields:    
  3. Angus DC, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Berry L, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Buzgau A, Cheng AC, de Jong M, Detry M, Estcourt L, Fitzgerald M, Goossens H, Green C, Haniffa R, Higgins AM, Horvat C, Hullegie SJ, Kruger P, Lamontagne F, Lawler PR, Linstrum K, Litton E, Lorenzi E, Marshall J, McAuley D, McGlothin A, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Parker J, Rowan K, Sanil A, Santos M, Saunders C, Seymour C, Turner A, van de Veerdonk F, Venkatesh B, Zarychanski R, Berry S, Lewis RJ, McArthur C, Webb SA, Gordon AC, Al-Beidh F, Angus D, Annane D, Arabi Y, van Bentum-Puijk W, Berry S, Beane A, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Cheng A, De Jong M, Derde L, Estcourt L, Goossens H, Gordon A, Green C, Haniffa R, Lamontagne F, Lawler P, Litton E, Marshall J, McAuley D, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Rowan K, Seymour C, Turner A, van de Veerdonk F, Webb S, Zarychanski R, Campbell L, Forbes A, Gattas D, Heritier S, Higgins L, Kruger P, Peake S, Presneill J, Seppelt I, Trapani T, Young P, Bagshaw S, Daneman N, Ferguson N, Misak C, Santos M, Hullegie S, Pletz M, Rohde G, Rowan K, Alexander B, Basile K, Girard T, Horvat C, Huang D, Linstrum K, Vates J, Beasley R, Fowler R, McGloughlin S, Morpeth S, Paterson D, Venkatesh B, Uyeki T, Baillie K, Duffy E, Fowler R, Hills T, Orr K, Patanwala A, Tong S, Netea M, Bihari S, Carrier M, Fergusson D, Goligher E, Haidar G, Hunt B, Kumar A, Laffan M, Lawless P, Lother S, McCallum P, Middeldopr S, McQuilten Z, Neal M, Pasi J, Schutgens R, Stanworth S, Turgeon A, Weissman A, Adhikari N, Anstey M, Brant E, de Man A, Lamonagne F, Masse MH, Udy A, Arnold D, Begin P, Charlewood R, Chasse M, Coyne M, Cooper J, Daly J, Gosbell I, Harvala-Simmonds H, Hills T, MacLennan S, Menon D, McDyer J, Pridee N, Roberts D, Shankar-Hari M, Thomas H, Tinmouth A, Triulzi D, Walsh T, Wood E, Calfee C, O’Kane C, Shyamsundar M, Sinha P, Thompson T, Young I, Bihari S, Hodgson C, Laffey J, McAuley D, Orford N, Neto A, Detry M, Fitzgerald M, Lewis R, McGlothlin A, Sanil A, Saunders C, Berry L, Lorenzi E, Miller E, Singh V, Zammit C, van Bentum Puijk W, Bouwman W, Mangindaan Y, Parker L, Peters S, Rietveld I, Raymakers K, Ganpat R, Brillinger N, Markgraf R, Ainscough K, Brickell K, Anjum A, Lane JB, Richards-Belle A, Saull M, Wiley D, Bion J, Connor J, Gates S, Manax V, van der Poll T, Reynolds J, van Beurden M, Effelaar E, Schotsman J, Boyd C, Harland C, Shearer A, Wren J, Clermont G, Garrard W, Kalchthaler K, King A, Ricketts D, Malakoutis S, Marroquin O, Music E, Quinn K, Cate H, Pearson K, Collins J, Hanson J, Williams P, Jackson S, Asghar A, Dyas S, Sutu M, Murphy S, Williamson D, Mguni N, Potter A, Porter D, Goodwin J, Rook C, Harrison S, Williams H, Campbell H, Lomme K, Williamson J, Sheffield J, van’t Hoff W, McCracken P, Young M, Board J, Mart E, Knott C, Smith J, Boschert C, Affleck J, Ramanan M, D’Souza R, Pateman K, Shakih A, Cheung W, Kol M, Wong H, Shah A, Wagh A, Simpson J, Duke G, Chan P, Cartner B, Hunter S, Laver R, Shrestha T, Regli A, Pellicano A, McCullough J, Tallott M, Kumar N, Panwar R, Brinkerhoff G, Koppen C, Cazzola F, Brain M, Mineall S, Fischer R, Biradar V, Soar N, White H, Estensen K, Morrison L, Smith J, Cooper M, Health M, Shehabi Y, Al-Bassam W, Hulley A, Whitehead C, Lowrey J, Gresha R, Walsham J, Meyer J, Harward M, Venz E, Williams P, Kurenda C, Smith K, Smith M, Garcia R, Barge D, Byrne D, Byrne K, Driscoll A, Fortune L, Janin P, Yarad E, Hammond N, Bass F, Ashelford A, Waterson S, Wedd S, McNamara R, Buhr H, Coles J, Schweikert S, Wibrow B, Rauniyar R, Myers E, Fysh E, Dawda A, Mevavala B, Litton E, Ferrier J, Nair P, Buscher H, Reynolds C, Santamaria J, Barbazza L, Homes J, Smith R, Murray L, Brailsford J, Forbes L, Maguire T, Mariappa V, Smith J, Simpson S, Maiden M, Bone A, Horton M, Salerno T, Sterba M, et al. Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial. JAMA. 2020 10 06; 324(13):1317-1329. PMID: 32876697.
    Citations: 137     Fields:    Translation:HumansCellsPHPublic Health
  4. Fusar-Poli P, Spencer T, De Micheli A, Curzi V, Nandha S, McGuire P. Outreach and support in South-London (OASIS) 2001-2020: Twenty years of early detection, prognosis and preventive care for young people at risk of psychosis. Eur Neuropsychopharmacol. 2020 10; 39:111-122. PMID: 32921544.
    Citations: 2     Fields:    Translation:Humans
  5. Goetter EM, Blackburn AM, Stasko C, Han Y, Brenner LH, Lejeune S, Tanev KS, Spencer TJ, Wright EC. Comparative effectiveness of prolonged exposure and cognitive processing therapy for military service members in an intensive treatment program. Psychol Trauma. 2020 Sep 10. PMID: 32915044.
    Citations: 1     Fields:    
  6. McCarthy DM, Lowe SE, Morgan TJ, Cannon EN, Biederman J, Spencer TJ, Bhide PG. Transgenerational transmission of behavioral phenotypes produced by exposure of male mice to saccharin and nicotine. Sci Rep. 2020 07 20; 10(1):11974. PMID: 32686722.
    Citations: 1     Fields:    Translation:AnimalsCells
  7. Sylvia LG, Bui E, Chudnofsky R, Lakin L, McCarthy MD, Gupta CT, Furbish K, Mehta DH, Denninger JW, Park ER, Fricchione GL, Spencer TJ. A pilot study of a mind-body stress management program for student veterans. Complement Ther Clin Pract. 2020 Aug; 40:101221. PMID: 32891295.
    Citations:    Fields:    Translation:Humans
  8. Biederman J, DiSalvo M, Woodworth KY, Fried R, Uchida M, Biederman I, Spencer TJ, Surman C, Faraone SV. Toward operationalizing deficient emotional self-regulation in newly referred adults with ADHD: A receiver operator characteristic curve analysis. Eur Psychiatry. 2020 02 24; 63(1):e21. PMID: 32093797.
    Citations: 4     Fields:    Translation:Humans
  9. Hirschberg R, Sylvia LG, Wright EC, Gupta CT, McCarthy MD, Harward LK, Goetter EM, Boland H, Tanev K, Spencer TJ. Collaborative Songwriting Intervention for Veterans with Post-Traumatic Stress Disorder. J Altern Complement Med. 2020 Mar; 26(3):198-203. PMID: 31985263.
    Citations:    Fields:    Translation:Humans
  10. Sylvia L, West E, Blackburn AM, Gupta C, Bui E, Mahoney T, Duncan G, Wright EC, Lejeune S, Spencer TJ. Acceptability of an adjunct equine-assisted activities and therapies program for veterans with posttraumatic stress disorder and/or traumatic brain injury. J Integr Med. 2020 Mar; 18(2):169-173. PMID: 31996299.
    Citations: 2     Fields:    Translation:HumansAnimals
  11. Spencer T, Noyes E, Biederman J. Telemedicine in the Management of ADHD: Literature Review of Telemedicine in ADHD. J Atten Disord. 2020 01; 24(1):3-9. PMID: 31257978.
    Citations: 9     Fields:    Translation:Humans
  12. Gomeni R, Fang LL, Bressolle-Gomeni F, Spencer TJ, Faraone SV, Babiskin A. A General Framework for Assessing In vitro/In vivo Correlation as a Tool for Maximizing the Benefit-Risk Ratio of a Treatment Using a Convolution-Based Modeling Approach. CPT Pharmacometrics Syst Pharmacol. 2019 02; 8(2):97-106. PMID: 30659771.
    Citations: 4     Fields:    Translation:Humans
  13. Findling RL, Adler LA, Spencer TJ, Goldman R, Hopkins SC, Koblan KS, Kent J, Hsu J, Loebel A. Dasotraline in Children with Attention-Deficit/Hyperactivity Disorder: A Six-Week, Placebo-Controlled, Fixed-Dose Trial. J Child Adolesc Psychopharmacol. 2019 03; 29(2):80-89. PMID: 30694697.
    Citations: 1     Fields:    Translation:Humans
  14. McCarthy DM, Morgan TJ, Lowe SE, Williamson MJ, Spencer TJ, Biederman J, Bhide PG. Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants. PLoS Biol. 2018 10; 16(10):e2006497. PMID: 30325916.
    Citations: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  15. Silverstein MJ, Faraone SV, Leon TL, Biederman J, Spencer TJ, Adler LA. The Relationship Between Executive Function Deficits and DSM-5-Defined ADHD Symptoms. J Atten Disord. 2020 01; 24(1):41-51. PMID: 30296883.
    Citations: 8     Fields:    Translation:Humans
  16. Iaccarino MA, Fitzgerald M, Pulli A, Woodworth KY, Spencer TJ, Zafonte R, Biederman J. Sport concussion and attention deficit hyperactivity disorder in student athletes: A cohort study. Neurol Clin Pract. 2018 Oct; 8(5):403-411. PMID: 30564494.
    Citations: 3     
  17. Abrams J, Faraone SV, Woodworth KY, Spencer TJ, Biederman I, Biederman J. Are Adult ADHD Patients Good Informants of Their Symptoms? A Qualitative Literature Review of Concordance Between Clinician and Self-Report ADHD Symptoms. J Nerv Ment Dis. 2018 09; 206(9):739-743. PMID: 30124570.
    Citations: 1     Fields:    Translation:Humans
  18. Biederman J, Fitzgerald M, Spencer TJ, Adler LA, Abrams J, Biederman I, Faraone SV. Informativeness of Self-Reports of ADHD Symptoms in Monitoring Response to Stimulant Treatment in Clinically Referred Adults With ADHD. J Atten Disord. 2020 02; 24(3):420-424. PMID: 29804496.
    Citations:    Fields:    Translation:Humans
  19. Zhang L, Spencer TJ, Biederman J, Bhide PG. Attention and working memory deficits in a perinatal nicotine exposure mouse model. PLoS One. 2018; 13(5):e0198064. PMID: 29795664.
    Citations: 14     Fields:    Translation:Animals
  20. Spencer TJ, Bhide P, Zhu J, Faraone SV, Fitzgerald M, Yule AM, Uchida M, Spencer AE, Hall AM, Koster AJ, Feinberg L, Kassabian S, Storch B, Biederman J. The Mixed Opioid Receptor Antagonist Naltrexone Mitigates Stimulant-Induced Euphoria: A Double-Blind, Placebo-Controlled Trial of Naltrexone. J Clin Psychiatry. 2018 Mar/Apr; 79(2). PMID: 29617066.
    Citations:    Fields:    Translation:Humans
  21. Silverstein MJ, Faraone SV, Alperin S, Leon TL, Biederman J, Spencer TJ, Adler LA. Validation of the Expanded Versions of the Adult ADHD Self-Report Scale v1.1 Symptom Checklist and the Adult ADHD Investigator Symptom Rating Scale. J Atten Disord. 2019 08; 23(10):1101-1110. PMID: 29419345.
    Citations: 7     Fields:    Translation:Humans
  22. Spencer TJ, Bhide P, Zhu J, Faraone SV, Fitzgerald M, Yule AM, Uchida M, Spencer AE, Hall AM, Koster AJ, Biederman J. Opiate Antagonists Do Not Interfere With the Clinical Benefits of Stimulants in ADHD: A Double-Blind, Placebo-Controlled Trial of the Mixed Opioid Receptor Antagonist Naltrexone. J Clin Psychiatry. 2018 Jan/Feb; 79(1). PMID: 28640990.
    Citations:    Fields:    Translation:Humans
  23. Biederman J, Fitzgerald M, Uchida M, Spencer TJ, Fried R, Wicks J, Saunders A, Faraone SV. Towards operationalising internal distractibility (Mind Wandering) in adults with ADHD. Acta Neuropsychiatr. 2017 Dec; 29(6):330-336. PMID: 29151406.
    Citations: 1     Fields:    Translation:Humans
  24. Silverstein MJ, Faraone SV, Alperin S, Biederman J, Spencer TJ, Adler LA. How Informative Are Self-Reported Adult Attention-Deficit/Hyperactivity Disorder Symptoms? An Examination of the Agreement Between the Adult Attention-Deficit/Hyperactivity Disorder Self-Report Scale V1.1 and Adult Attention-Deficit/Hyperactivity Disorder Investigator Symptom Rating Scale. J Child Adolesc Psychopharmacol. 2018 06; 28(5):339-349. PMID: 29172673.
    Citations: 4     Fields:    Translation:Humans
  25. Ustun B, Adler LA, Rudin C, Faraone SV, Spencer TJ, Berglund P, Gruber MJ, Kessler RC. The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5. JAMA Psychiatry. 2017 05 01; 74(5):520-527. PMID: 28384801.
    Citations: 31     Fields:    Translation:Humans
  26. Adler LA, Faraone SV, Spencer TJ, Berglund P, Alperin S, Kessler RC. The structure of adult ADHD. Int J Methods Psychiatr Res. 2017 03; 26(1). PMID: 28211596.
    Citations: 8     Fields:    Translation:Humans
  27. Spencer AE, Marin MF, Milad MR, Spencer TJ, Bogucki OE, Pope AL, Plasencia N, Hughes B, Pace-Schott EF, Fitzgerald M, Uchida M, Biederman J. Abnormal fear circuitry in Attention Deficit Hyperactivity Disorder: A controlled magnetic resonance imaging study. Psychiatry Res Neuroimaging. 2017 Apr 30; 262:55-62. PMID: 28235692.
    Citations: 3     Fields:    Translation:Humans
  28. Zhu J, Fan F, McCarthy DM, Zhang L, Cannon EN, Spencer TJ, Biederman J, Bhide PG. A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes. Int J Dev Neurosci. 2017 May; 58:26-34. PMID: 28179105.
    Citations: 12     Fields:    Translation:Animals
  29. Biederman J, Fitzgerald M, Spencer TJ, Bhide PG, McCarthy DM, Woodworth KY, Saunders A, Faraone SV. Is Paternal Smoking at Conception a Risk for ADHD? A Controlled Study in Youth With and Without ADHD. J Atten Disord. 2020 09; 24(11):1493-1496. PMID: 28152645.
    Citations: 3     Fields:    Translation:Humans
  30. Biederman J, Fried R, Tarko L, Surman C, Spencer T, Pope A, Grossman R, McDermott K, Woodworth KY, Faraone SV. Memantine in the Treatment of Executive Function Deficits in Adults With ADHD. J Atten Disord. 2017 02; 21(4):343-352. PMID: 24970718.
    Citations: 3     Fields:    Translation:HumansCells
  31. Spencer AE, Faraone SV, Bogucki OE, Pope AL, Uchida M, Milad MR, Spencer TJ, Woodworth KY, Biederman J. Examining the association between posttraumatic stress disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. J Clin Psychiatry. 2016 Jan; 77(1):72-83. PMID: 26114394.
    Citations: 5     Fields:    Translation:Humans
  32. Mattfeld AT, Whitfield-Gabrieli S, Biederman J, Spencer T, Brown A, Fried R, Gabrieli JD. Dissociation of working memory impairments and attention-deficit/hyperactivity disorder in the brain. Neuroimage Clin. 2016; 10:274-82. PMID: 26900567.
    Citations: 15     Fields:    Translation:Humans
  33. Biederman J, Feinberg L, Chan J, Adeyemo BO, Woodworth KY, Panis W, McGrath N, Bhatnagar S, Spencer TJ, Uchida M, Kenworthy T, Grossman R, Zafonte R, Faraone SV. Mild Traumatic Brain Injury and Attention-Deficit Hyperactivity Disorder in Young Student Athletes. J Nerv Ment Dis. 2015 Nov; 203(11):813-9. PMID: 26461480.
    Citations: 15     Fields:    Translation:Humans
  34. Uchida M, Spencer TJ, Faraone SV, Biederman J. Adult Outcome of ADHD: An Overview of Results From the MGH Longitudinal Family Studies of Pediatrically and Psychiatrically Referred Youth With and Without ADHD of Both Sexes. J Atten Disord. 2018 04; 22(6):523-534. PMID: 26396145.
    Citations: 27     Fields:    Translation:Humans
  35. Biederman J, Chan J, Faraone SV, Woodworth KY, Spencer TJ, Wozniak JR. A Familial Risk Analysis of Emotional Dysregulation: A Controlled Study. J Atten Disord. 2018 07; 22(9):848-854. PMID: 26220788.
    Citations: 1     Fields:    Translation:Humans
  36. Biederman J, Martelon M, Woodworth KY, Spencer TJ, Faraone SV. Is Maternal Smoking During Pregnancy a Risk Factor for Cigarette Smoking in Offspring? A Longitudinal Controlled Study of ADHD Children Grown Up. J Atten Disord. 2017 Oct; 21(12):975-985. PMID: 25416463.
    Citations: 6     Fields:    Translation:Humans
  37. Spencer TJ, Faraone SV, Tarko L, McDermott K, Biederman J. Attention-deficit/hyperactivity disorder and adverse health outcomes in adults. J Nerv Ment Dis. 2014 Oct; 202(10):725-31. PMID: 25211634.
    Citations: 12     Fields:    Translation:Humans
  38. Adeyemo BO, Biederman J, Zafonte R, Kagan E, Spencer TJ, Uchida M, Kenworthy T, Spencer AE, Faraone SV. Mild traumatic brain injury and ADHD: a systematic review of the literature and meta-analysis. J Atten Disord. 2014 Oct; 18(7):576-84. PMID: 25047040.
    Citations: 22     Fields:    Translation:Humans
  39. Mattfeld AT, Gabrieli JD, Biederman J, Spencer T, Brown A, Kotte A, Kagan E, Whitfield-Gabrieli S. Brain differences between persistent and remitted attention deficit hyperactivity disorder. Brain. 2014 Sep; 137(Pt 9):2423-8. PMID: 24916335.
    Citations: 29     Fields:    Translation:Humans
  40. Uchida M, Faraone SV, Martelon M, Kenworthy T, Woodworth KY, Spencer TJ, Wozniak JR, Biederman J. Further evidence that severe scores in the aggression/anxiety-depression/attention subscales of child behavior checklist (severe dysregulation profile) can screen for bipolar disorder symptomatology: a conditional probability analysis. J Affect Disord. 2014 Aug; 165:81-6. PMID: 24882182.
    Citations: 6     Fields:    Translation:Humans
  41. Antshel KM, Biederman J, Spencer TJ, Faraone SV. The Neuropsychological Profile of Comorbid Post-Traumatic Stress Disorder in Adult ADHD. J Atten Disord. 2016 12; 20(12):1047-1055. PMID: 24567364.
    Citations: 5     Fields:    Translation:Humans
  42. Zhu J, Lee KP, Spencer TJ, Biederman J, Bhide PG. Transgenerational transmission of hyperactivity in a mouse model of ADHD. J Neurosci. 2014 Feb 19; 34(8):2768-73. PMID: 24553919.
    Citations: 26     Fields:    Translation:Animals
  43. Makris N, Liang L, Biederman J, Valera EM, Brown AB, Petty C, Spencer TJ, Faraone SV, Seidman LJ. Toward Defining the Neural Substrates of ADHD: A Controlled Structural MRI Study in Medication-Naïve Adults. J Atten Disord. 2015 Nov; 19(11):944-53. PMID: 24189200.
    Citations: 15     Fields:    Translation:HumansCells
  44. Spencer TJ, Brown A, Seidman LJ, Valera EM, Makris N, Lomedico A, Faraone SV, Biederman J. Effect of psychostimulants on brain structure and function in ADHD: a qualitative literature review of magnetic resonance imaging-based neuroimaging studies. J Clin Psychiatry. 2013 Sep; 74(9):902-17. PMID: 24107764.
    Citations: 33     Fields:    Translation:Humans
  45. Biederman J, Wozniak J, Martelon MK, Spencer TJ, Woodworth Y, Joshi G, Spencer A, Uchida M, Kotte A, Faraone SV. Can pediatric bipolar-I disorder be diagnosed in the context of posttraumatic stress disorder? A familial risk analysis. Psychiatry Res. 2013 Aug 15; 208(3):215-24. PMID: 23790757.
    Citations: 1     Fields:    Translation:Humans
  46. Biederman J, Petty C, Spencer TJ, Woodworth KY, Bhide P, Zhu J, Faraone SV. Is ADHD a risk for posttraumatic stress disorder (PTSD)? Results from a large longitudinal study of referred children with and without ADHD. World J Biol Psychiatry. 2014 Jan; 15(1):49-55. PMID: 23607442.
    Citations: 7     Fields:    Translation:Humans
  47. Surman CB, Biederman J, Spencer T, Miller CA, Petty CR, Faraone SV. Neuropsychological Deficits Are Not Predictive of Deficient Emotional Self-Regulation in Adults With ADHD. J Atten Disord. 2015 Dec; 19(12):1046-53. PMID: 23503813.
    Citations: 7     Fields:    Translation:Humans
  48. Antshel KM, Kaul P, Biederman J, Spencer TJ, Hier BO, Hendricks K, Faraone SV. Posttraumatic stress disorder in adult attention-deficit/hyperactivity disorder: clinical features and familial transmission. J Clin Psychiatry. 2013 Mar; 74(3):e197-204. PMID: 23561240.
    Citations: 10     Fields:    Translation:Humans
  49. Surman CB, Biederman J, Spencer T, Miller CA, McDermott KM, Faraone SV. Understanding deficient emotional self-regulation in adults with attention deficit hyperactivity disorder: a controlled study. Atten Defic Hyperact Disord. 2013 Sep; 5(3):273-81. PMID: 23413201.
    Citations: 21     Fields:    Translation:Humans
  50. Spencer TJ, Biederman J, Faraone SV, Madras BK, Bonab AA, Dougherty DD, Batchelder H, Clarke A, Fischman AJ. Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects. Biol Psychiatry. 2013 Jul 15; 74(2):84-9. PMID: 23273726.
    Citations: 22     Fields:    Translation:HumansCells
  51. Biederman J, Martelon M, Faraone SV, Woodworth KY, Spencer TJ, Wozniak JR. Personal and familial correlates of bipolar (BP)-I disorder in children with a diagnosis of BP-I disorder with a positive child behavior checklist (CBCL)-severe dysregulation profile: a controlled study. J Affect Disord. 2013 May; 147(1-3):164-70. PMID: 23164462.
    Citations: 8     Fields:    Translation:Humans
  52. Hammerness P, Joshi G, Doyle R, Georgiopoulos A, Geller D, Spencer T, Petty CR, Faraone SV, Biederman J. Do stimulants reduce the risk for cigarette smoking in youth with attention-deficit hyperactivity disorder? A prospective, long-term, open-label study of extended-release methylphenidate. J Pediatr. 2013 Jan; 162(1):22-7.e2. PMID: 22878114.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  53. Zhu J, Zhang X, Xu Y, Spencer TJ, Biederman J, Bhide PG. Prenatal nicotine exposure mouse model showing hyperactivity, reduced cingulate cortex volume, reduced dopamine turnover, and responsiveness to oral methylphenidate treatment. J Neurosci. 2012 Jul 04; 32(27):9410-8. PMID: 22764249.
    Citations: 38     Fields:    Translation:Animals
  54. Biederman J, Spencer TJ, Petty C, Hyder LL, O'Connor KB, Surman CB, Faraone SV. Longitudinal course of deficient emotional self-regulation CBCL profile in youth with ADHD: prospective controlled study. Neuropsychiatr Dis Treat. 2012; 8:267-76. PMID: 22848182.
    Citations: 28     
  55. Spencer TJ, Madras BK, Fischman AJ, Krause J, La Fougère C. Striatal dopamine transporter binding in adults with ADHD. Am J Psychiatry. 2012 Jun; 169(6):665; author reply 666. PMID: 22684601.
    Citations: 2     Fields:    Translation:Humans
  56. Makris N, Seidman LJ, Brown A, Valera EM, Kaiser JR, Petty CR, Liang L, Aleardi M, Boriel D, Henderson CS, Giddens M, Faraone SV, Spencer TJ, Biederman J. Further understanding of the comorbidity between Attention-Deficit/Hyperactivity Disorder and bipolar disorder in adults: an MRI study of cortical thickness. Psychiatry Res. 2012 Apr 30; 202(1):1-11. PMID: 22640688.
    Citations: 2     Fields:    Translation:Humans
  57. Adler LA, Shaw DM, Spencer TJ, Newcorn JH, Hammerness P, Sitt DJ, Minerly C, Davidow JV, Faraone SV. Preliminary examination of the reliability and concurrent validity of the attention-deficit/hyperactivity disorder self-report scale v1.1 symptom checklist to rate symptoms of attention-deficit/hyperactivity disorder in adolescents. J Child Adolesc Psychopharmacol. 2012 Jun; 22(3):238-44. PMID: 22537184.
    Citations: 17     Fields:    Translation:Humans
  58. Biederman J, Petty CR, Day H, Goldin RL, Spencer T, Faraone SV, Surman CB, Wozniak J. Severity of the aggression/anxiety-depression/attention child behavior checklist profile discriminates between different levels of deficits in emotional regulation in youth with attention-deficit hyperactivity disorder. J Dev Behav Pediatr. 2012 Apr; 33(3):236-43. PMID: 22278125.
    Citations: 35     Fields:    Translation:Humans
  59. Surman CB, Hammerness PG, Petty C, Spencer T, Doyle R, Napolean S, Chu N, Yorks D, Biederman J. A pilot open label prospective study of memantine monotherapy in adults with ADHD. World J Biol Psychiatry. 2013 May; 14(4):291-8. PMID: 22436083.
    Citations: 7     Fields:    Translation:Humans
  60. Spencer TJ, Biederman J, Martin JM, Moorehead TM, Mirto T, Clarke A, Batchelder H, Faraone SV. Importance of pharmacokinetic profile and timing of coadministration of short- and long-acting formulations of methylphenidate on patterns of subjective responses and abuse potential. Postgrad Med. 2012 Jan; 124(1):166-73. PMID: 22314126.
    Citations: 4     Fields:    Translation:Humans
  61. Spencer TJ, Bonab AA, Dougherty DD, Mirto T, Martin J, Clarke A, Fischman AJ. Understanding the central pharmacokinetics of spheroidal oral drug absorption system (SODAS) dexmethylphenidate: a positron emission tomography study of dopamine transporter receptor occupancy measured with C-11 altropane. J Clin Psychiatry. 2012 Mar; 73(3):346-52. PMID: 22154896.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  62. Spencer TJ, Faraone SV, Surman CB, Petty C, Clarke A, Batchelder H, Wozniak J, Biederman J. Toward defining deficient emotional self-regulation in children with attention-deficit/hyperactivity disorder using the Child Behavior Checklist: a controlled study. Postgrad Med. 2011 Sep; 123(5):50-9. PMID: 21904086.
    Citations: 28     Fields:    Translation:Humans
  63. Adler LA, Shaw DM, Spencer TJ, Newcorn JH, Sitt DJ, Minerly AE, Davidow JV, Faraone SV. Preliminary reliability and validity of a new time-sensitive ADHD symptom scale in adolescents with ADHD. Postgrad Med. 2011 Sep; 123(5):7-13. PMID: 21904082.
    Citations:    Fields:    Translation:Humans
  64. Biederman J, Mick E, Spencer T, Surman C, Faraone SV. Is response to OROS-methylphenidate treatment moderated by treatment with antidepressants or psychiatric comorbidity? A secondary analysis from a large randomized double blind study of adults with ADHD. CNS Neurosci Ther. 2012 Feb; 18(2):126-32. PMID: 22070421.
    Citations: 5     Fields:    Translation:HumansCells
  65. Brown AB, Biederman J, Valera E, Makris N, Doyle A, Whitfield-Gabrieli S, Mick E, Spencer T, Faraone S, Seidman L. Relationship of DAT1 and adult ADHD to task-positive and task-negative working memory networks. Psychiatry Res. 2011 Jul 30; 193(1):7-16. PMID: 21596533.
    Citations: 25     Fields:    Translation:HumansCells
  66. Faraone SV, Spencer TJ, Kollins SH, Glatt SJ, Goodman D. Dose response effects of lisdexamfetamine dimesylate treatment in adults with ADHD: an exploratory study. J Atten Disord. 2012 Feb; 16(2):118-27. PMID: 21527575.
    Citations: 3     Fields:    Translation:Humans
  67. Zhu J, Spencer TJ, Liu-Chen LY, Biederman J, Bhide PG. Methylphenidate and µ opioid receptor interactions: a pharmacological target for prevention of stimulant abuse. Neuropharmacology. 2011 Jul-Aug; 61(1-2):283-92. PMID: 21545805.
    Citations: 7     Fields:    Translation:AnimalsCells
  68. Surman CB, Biederman J, Spencer T, Yorks D, Miller CA, Petty CR, Faraone SV. Deficient emotional self-regulation and adult attention deficit hyperactivity disorder: a family risk analysis. Am J Psychiatry. 2011 Jun; 168(6):617-23. PMID: 21498464.
    Citations: 27     Fields:    Translation:Humans
  69. Biederman J, Mick E, Fried R, Wilner N, Spencer TJ, Faraone SV. Are stimulants effective in the treatment of executive function deficits? Results from a randomized double blind study of OROS-methylphenidate in adults with ADHD. Eur Neuropsychopharmacol. 2011 Jul; 21(7):508-15. PMID: 21303732.
    Citations: 8     Fields:    Translation:Humans
  70. Adler LA, Shaw DM, Spencer TJ, Newcorn JH, Sitt DJ, Morrill M, Davidow JV, Glatt SJ, Faraone SV. Reliability and validity of the Time-Sensitive ADHD Symptom Scale in adults. Compr Psychiatry. 2011 Nov-Dec; 52(6):769-73. PMID: 21306705.
    Citations: 1     Fields:    Translation:Humans
  71. Trzepacz PT, Spencer TJ, Zhang S, Bangs ME, Witte MM, Desaiah D. Effect of atomoxetine on Tanner stage sexual development in children and adolescents with attention deficit/hyperactivity disorder: 18-month results from a double-blind, placebo-controlled trial. Curr Med Res Opin. 2011; 27 Suppl 2:45-52. PMID: 21973230.
    Citations: 2     Fields:    Translation:Humans
  72. Seidman LJ, Biederman J, Liang L, Valera EM, Monuteaux MC, Brown A, Kaiser J, Spencer T, Faraone SV, Makris N. Gray matter alterations in adults with attention-deficit/hyperactivity disorder identified by voxel based morphometry. Biol Psychiatry. 2011 May 01; 69(9):857-66. PMID: 21183160.
    Citations: 61     Fields:    Translation:HumansCells
  73. Spencer TJ, Madras BK, Bonab AA, Dougherty DD, Clarke A, Mirto T, Martin J, Fischman AJ. A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride. Biol Psychiatry. 2010 Nov 15; 68(10):964-70. PMID: 21035624.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  74. Biederman J, Spencer TJ, Monuteaux MC, Faraone SV. A naturalistic 10-year prospective study of height and weight in children with attention-deficit hyperactivity disorder grown up: sex and treatment effects. J Pediatr. 2010 Oct; 157(4):635-40, 640.e1. PMID: 20605163.
    Citations: 29     Fields:    Translation:Humans
  75. Biederman J, Mick E, Surman C, Doyle R, Hammerness P, Kotarski M, Spencer T. A randomized, 3-phase, 34-week, double-blind, long-term efficacy study of osmotic-release oral system-methylphenidate in adults with attention-deficit/hyperactivity disorder. J Clin Psychopharmacol. 2010 Oct; 30(5):549-53. PMID: 20814332.
    Citations: 27     Fields:    Translation:HumansCellsCTClinical Trials
  76. Wilens TE, Spencer TJ. Understanding attention-deficit/hyperactivity disorder from childhood to adulthood. Postgrad Med. 2010 Sep; 122(5):97-109. PMID: 20861593.
    Citations: 43     Fields:    Translation:Humans
  77. Valera EM, Spencer RM, Zeffiro TA, Makris N, Spencer TJ, Faraone SV, Biederman J, Seidman LJ. Neural substrates of impaired sensorimotor timing in adult attention-deficit/hyperactivity disorder. Biol Psychiatry. 2010 Aug 15; 68(4):359-67. PMID: 20619827.
    Citations: 39     Fields:    Translation:Humans
  78. Surman CB, Monuteaux MC, Petty CR, Faraone SV, Spencer TJ, Chu NF, Biederman J. Representativeness of participants in a clinical trial for attention-deficit/hyperactivity disorder? Comparison with adults from a large observational study. J Clin Psychiatry. 2010 Dec; 71(12):1612-6. PMID: 20816030.
    Citations: 18     Fields:    Translation:Humans
  79. Spencer TJ, Mick E, Surman CB, Hammerness P, Doyle R, Aleardi M, Kotarski M, Williams CG, Biederman J. A randomized, single-blind, substitution study of OROS methylphenidate (Concerta) in ADHD adults receiving immediate release methylphenidate. J Atten Disord. 2011 May; 15(4):286-94. PMID: 20495161.
    Citations: 8     Fields:    Translation:Humans
  80. Rios JJ, Fleming JG, Bryant UK, Carter CN, Huber JC, Long MT, Spencer TE, Adelson DL. OAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horses. PLoS One. 2010 May 07; 5(5):e10537. PMID: 20479874.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  81. Wilens TE, Prince JB, Waxmonsky J, Doyle R, Spencer T, Martelon M, Evans M. An Open Trial of Sustained Release Bupropion for Attention-Deficit/Hyperactivity Disorder in Adults with ADHD plus Substance Use Disorders. J ADHD Relat Disord. 2010 Apr 01; 1(3):25-35. PMID: 22500195.
    Citations: 5     
  82. Brown AB, Biederman J, Valera EM, Doyle AE, Bush G, Spencer T, Monuteaux MC, Mick E, Whitfield-Gabrieli S, Makris N, LaViolette PS, Oscar-Berman M, Faraone SV, Seidman LJ. Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorder. . 2010 Mar 05; 153B(2):365-375. PMID: 19676101.
    Citations: 20     Translation:Humans
  83. Spencer TJ, Bonab AA, Dougherty DD, Martin J, McDonnell T, Fischman AJ. A PET study examining pharmacokinetics and dopamine transporter occupancy of two long-acting formulations of methylphenidate in adults. Int J Mol Med. 2010 Feb; 25(2):261-5. PMID: 20043136.
    Citations: 4     Fields:    Translation:Humans
  84. Biederman J, Petty CR, Monuteaux MC, Fried R, Byrne D, Mirto T, Spencer T, Wilens TE, Faraone SV. Adult psychiatric outcomes of girls with attention deficit hyperactivity disorder: 11-year follow-up in a longitudinal case-control study. Am J Psychiatry. 2010 Apr; 167(4):409-17. PMID: 20080984.
    Citations: 69     Fields:    Translation:Humans
  85. Faraone SV, Spencer TJ, Kollins SH, Glatt SJ. Effects of lisdexamfetamine dimesylate treatment for ADHD on growth. J Am Acad Child Adolesc Psychiatry. 2010 Jan; 49(1):24-32. PMID: 20215923.
    Citations: 13     Fields:    Translation:Humans
  86. Bott RC, Ashley RL, Henkes LE, Antoniazzi AQ, Bruemmer JE, Niswender GD, Bazer FW, Spencer TE, Smirnova NP, Anthony RV, Hansen TR. Uterine vein infusion of interferon tau (IFNT) extends luteal life span in ewes. Biol Reprod. 2010 Apr; 82(4):725-35. PMID: 20042537.
    Citations: 20     Fields:    Translation:AnimalsCells
  87. Brown TE, Holdnack J, Saylor K, Adler L, Spencer T, Williams DW, Padival AK, Schuh K, Trzepacz PT, Kelsey D. Effect of atomoxetine on executive function impairments in adults with ADHD. J Atten Disord. 2011 Feb; 15(2):130-8. PMID: 20026871.
    Citations: 11     Fields:    Translation:Humans
  88. Biederman J, Petty CR, Ten Haagen KS, Small J, Doyle AE, Spencer T, Mick E, Monuteaux MC, Smoller JW, Faraone SV. Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorder. Psychiatry Res. 2009 Dec 30; 170(2-3):199-203. PMID: 19906444.
    Citations: 14     Fields:    Translation:HumansCells
  89. Wilens TE, Biederman J, Faraone SV, Martelon M, Westerberg D, Spencer TJ. Presenting ADHD symptoms, subtypes, and comorbid disorders in clinically referred adults with ADHD. J Clin Psychiatry. 2009 Nov; 70(11):1557-62. PMID: 20031097.
    Citations: 50     Fields:    Translation:Humans
  90. Spencer TJ, Greenbaum M, Ginsberg LD, Murphy WR. Safety and effectiveness of coadministration of guanfacine extended release and psychostimulants in children and adolescents with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2009 Oct; 19(5):501-10. PMID: 19877974.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  91. Spencer TJ, Adler LA, Saylor KE, Brown TE, Holdnack JA, Schuh KJ, Trzepacz PT, Kelsey DK. Validation of the adult ADHD investigator symptom rating scale (AISRS). J Atten Disord. 2010 Jul; 14(1):57-68. PMID: 19794135.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  92. Childress AC, Spencer T, Lopez F, Gerstner O, Thulasiraman A, Muniz R, Post A. Efficacy and safety of dexmethylphenidate extended-release capsules administered once daily to children with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2009 Aug; 19(4):351-61. PMID: 19702487.
    Citations: 6     Fields:    Translation:Humans
  93. Balcioglu A, Ren JQ, McCarthy D, Spencer TJ, Biederman J, Bhide PG. Plasma and brain concentrations of oral therapeutic doses of methylphenidate and their impact on brain monoamine content in mice. Neuropharmacology. 2009 Dec; 57(7-8):687-93. PMID: 19631228.
    Citations: 21     Fields:    Translation:Animals
  94. Biederman J, Monuteaux MC, Spencer T, Wilens TE, Faraone SV. Do stimulants protect against psychiatric disorders in youth with ADHD? A 10-year follow-up study. Pediatrics. 2009 Jul; 124(1):71-8. PMID: 19564285.
    Citations: 56     Fields:    Translation:Humans
  95. Adler LA, Zimmerman B, Starr HL, Silber S, Palumbo J, Orman C, Spencer T. Efficacy and safety of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled, double-blind, parallel group, dose-escalation study. J Clin Psychopharmacol. 2009 Jun; 29(3):239-47. PMID: 19440077.
    Citations: 32     Fields:    Translation:Humans
  96. Biederman J, Petty CR, Wilens TE, Spencer T, Henin A, Faraone SV, Mick E, Monuteaux MC, Kenealy D, Mirto T, Wozniak J. Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorder. Bipolar Disord. 2009 May; 11(3):298-306. PMID: 19419387.
    Citations: 4     Fields:    Translation:Humans
  97. Hammerness P, Wilens T, Mick E, Spencer T, Doyle R, McCreary M, Becker J, Biederman J. Cardiovascular effects of longer-term, high-dose OROS methylphenidate in adolescents with attention deficit hyperactivity disorder. J Pediatr. 2009 Jul; 155(1):84-9, 89.e1. PMID: 19394037.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  98. Adler LA, Spencer T, McGough JJ, Jiang H, Muniz R. Long-term effectiveness and safety of dexmethylphenidate extended-release capsules in adult ADHD. J Atten Disord. 2009 Mar; 12(5):449-59. PMID: 19218542.
    Citations: 18     Fields:    Translation:Humans
  99. Adler LA, Spencer T, Brown TE, Holdnack J, Saylor K, Schuh K, Trzepacz PT, Williams DW, Kelsey D. Once-daily atomoxetine for adult attention-deficit/hyperactivity disorder: a 6-month, double-blind trial. J Clin Psychopharmacol. 2009 Feb; 29(1):44-50. PMID: 19142107.
    Citations: 36     Fields:    Translation:Humans
  100. Donnelly C, Bangs M, Trzepacz P, Jin L, Zhang S, Witte MM, Ball SG, Spencer TJ. Safety and tolerability of atomoxetine over 3 to 4 years in children and adolescents with ADHD. J Am Acad Child Adolesc Psychiatry. 2009 Feb; 48(2):176-85. PMID: 20040824.
    Citations: 21     Fields:    Translation:Humans
  101. Spencer TJ. Issues in the management of patients with complex attention-deficit hyperactivity disorder symptoms. CNS Drugs. 2009; 23 Suppl 1:9-20. PMID: 19621974.
    Citations: 4     Fields:    Translation:Humans
  102. Spencer TJ. Toward a new understanding of attention-deficit hyperactivity disorder: advances in research and treatment. CNS Drugs. 2009; 23 Suppl 1:5-8. PMID: 19621973.
    Citations: 1     Fields:    Translation:Humans
  103. Monuteaux MC, Seidman LJ, Faraone SV, Makris N, Spencer T, Valera E, Brown A, Bush G, Doyle AE, Hughes S, Helliesen M, Mick E, Biederman J. A preliminary study of dopamine D4 receptor genotype and structural brain alterations in adults with ADHD. . 2008 Dec 05; 147B(8):1436-41. PMID: 18951431.
    Citations: 16     Translation:Humans
  104. Spencer TJ, Landgraf JM, Adler LA, Weisler RH, Anderson CS, Youcha SH. Attention-deficit/hyperactivity disorder-specific quality of life with triple-bead mixed amphetamine salts (SPD465) in adults: results of a randomized, double-blind, placebo-controlled study. J Clin Psychiatry. 2008 Nov; 69(11):1766-75. PMID: 19026251.
    Citations: 8     Fields:    Translation:Humans
  105. Mick E, Kim JW, Biederman J, Wozniak J, Wilens T, Spencer T, Smoller JW, Faraone SV. Family based association study of pediatric bipolar disorder and the dopamine transporter gene (SLC6A3). . 2008 Oct 05; 147B(7):1182-5. PMID: 18361424.
    Citations: 21     Translation:Humans
  106. Spencer TJ. Adult ADHD: diversion and misuse of medications. CNS Spectr. 2008 Oct; 13(10 Suppl 15):9-13. PMID: 18955949.
    Citations:    Fields:    Translation:Humans
  107. Spencer TJ, Adler LA, Weisler RH, Youcha SH. Triple-bead mixed amphetamine salts (SPD465), a novel, enhanced extended-release amphetamine formulation for the treatment of adults with ADHD: a randomized, double-blind, multicenter, placebo-controlled study. J Clin Psychiatry. 2008 Sep; 69(9):1437-48. PMID: 19012813.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  108. Spencer TJ. Neurobiology and genetics of ADHD in adults. CNS Spectr. 2008 Sep; 13(9 Suppl 13):5-7. PMID: 18849903.
    Citations: 2     Fields: