Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Thomas J. Spencer, M.D.

Title
Institution
Department
Address
Phone

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. U01FD005240 (SPENCER, THOMAS J) Sep 10, 2014 - Aug 31, 2020
    FDA
    Pharmacokinetic Pharmacodynamic Studies of Methylphenidate Extended Release Products in Pediatric Attention Deficit Hyperactivity Disorder
    Role: Principal Investigator
  2. R01MH064019 (SPENCER, THOMAS J) Apr 24, 2003 - Jan 31, 2010
    NIH/NIMH
    Dopamine Transporter Binding by PET in Adult ADHD
    Role: Principal Investigator
  3. R29MH057511 (SPENCER, THOMAS J) May 1, 1998 - Feb 28, 2003
    NIH/NIMH
    CONTROLLED STUDY OF METHYLPHENIDATE IN ADULTS WITH ADHD
    Role: Principal Investigator
  4. K20MH001169 (SPENCER, THOMAS J) May 1, 1994 - Apr 30, 1999
    NIH/NIMH
    DESIPRAMINE IN CHILDREN AND ADOLESCENTS
    Role: Principal Investigator
  5. P51RR000168 (FLIER, JEFFREY S) Jun 1, 1978 - Apr 30, 2013
    NIH/NCRR
    New England Primate Research Center Base Grant
    Role: Co-Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Spencer T, Noyes E, Biederman J. Telemedicine in the Management of ADHD: Literature Review of Telemedicine in ADHD. J Atten Disord. 2019 Jul 01; 1087054719859081. PMID: 31257978.
    Citations:    
  2. Gomeni R, Fang LL, Bressolle-Gomeni F, Spencer TJ, Faraone SV, Babiskin A. A General Framework for Assessing In vitro/In vivo Correlation as a Tool for Maximizing the Benefit-Risk Ratio of a Treatment Using a Convolution-Based Modeling Approach. CPT Pharmacometrics Syst Pharmacol. 2019 Feb; 8(2):97-106. PMID: 30659771.
    Citations:    Fields:    
  3. Findling RL, Adler LA, Spencer TJ, Goldman R, Hopkins SC, Koblan KS, Kent J, Hsu J, Loebel A. Dasotraline in Children with Attention-Deficit/Hyperactivity Disorder: A Six-Week, Placebo-Controlled, Fixed-Dose Trial. J Child Adolesc Psychopharmacol. 2019 Mar; 29(2):80-89. PMID: 30694697.
    Citations:    Fields:    
  4. McCarthy DM, Morgan TJ, Lowe SE, Williamson MJ, Spencer TJ, Biederman J, Bhide PG. Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants. PLoS Biol. 2018 10; 16(10):e2006497. PMID: 30325916.
    Citations:    Fields:    
  5. Silverstein MJ, Faraone SV, Leon TL, Biederman J, Spencer TJ, Adler LA. The Relationship Between Executive Function Deficits and DSM-5-Defined ADHD Symptoms. J Atten Disord. 2018 Oct 08; 1087054718804347. PMID: 30296883.
    Citations:    Fields:    
  6. Iaccarino MA, Fitzgerald M, Pulli A, Woodworth KY, Spencer TJ, Zafonte R, Biederman J. Sport concussion and attention deficit hyperactivity disorder in student athletes: A cohort study. Neurol Clin Pract. 2018 Oct; 8(5):403-411. PMID: 30564494.
    Citations:    
  7. Abrams J, Faraone SV, Woodworth KY, Spencer TJ, Biederman I, Biederman J. Are Adult ADHD Patients Good Informants of Their Symptoms? A Qualitative Literature Review of Concordance Between Clinician and Self-Report ADHD Symptoms. J Nerv Ment Dis. 2018 Sep; 206(9):739-743. PMID: 30124570.
    Citations:    Fields:    
  8. Zhang L, Spencer TJ, Biederman J, Bhide PG. Attention and working memory deficits in a perinatal nicotine exposure mouse model. PLoS One. 2018; 13(5):e0198064. PMID: 29795664.
    Citations: 1     Fields:    Translation:Animals
  9. Biederman J, Fitzgerald M, Spencer TJ, Adler LA, Abrams J, Biederman I, Faraone SV. Informativeness of Self-Reports of ADHD Symptoms in Monitoring Response to Stimulant Treatment in Clinically Referred Adults With ADHD. J Atten Disord. 2018 May 01; 1087054718776425. PMID: 29804496.
    Citations:    Fields:    
  10. Spencer TJ, Bhide P, Zhu J, Faraone SV, Fitzgerald M, Yule AM, Uchida M, Spencer AE, Hall AM, Koster AJ, Feinberg L, Kassabian S, Storch B, Biederman J. The Mixed Opioid Receptor Antagonist Naltrexone Mitigates Stimulant-Induced Euphoria: A Double-Blind, Placebo-Controlled Trial of Naltrexone. J Clin Psychiatry. 2018 Mar/Apr; 79(2). PMID: 29617066.
    Citations:    Fields:    
  11. Silverstein MJ, Faraone SV, Alperin S, Leon TL, Biederman J, Spencer TJ, Adler LA. Validation of the Expanded Versions of the Adult ADHD Self-Report Scale v1.1 Symptom Checklist and the Adult ADHD Investigator Symptom Rating Scale. J Atten Disord. 2018 Feb 01; 1087054718756198. PMID: 29419345.
    Citations: 1     Fields:    
  12. Spencer TJ, Bhide P, Zhu J, Faraone SV, Fitzgerald M, Yule AM, Uchida M, Spencer AE, Hall AM, Koster AJ, Biederman J. Opiate Antagonists Do Not Interfere With the Clinical Benefits of Stimulants in ADHD: A Double-Blind, Placebo-Controlled Trial of the Mixed Opioid Receptor Antagonist Naltrexone. J Clin Psychiatry. 2018 Jan/Feb; 79(1). PMID: 28640990.
    Citations:    Fields:    
  13. Biederman J, Fitzgerald M, Uchida M, Spencer TJ, Fried R, Wicks J, Saunders A, Faraone SV. Towards operationalising internal distractibility (Mind Wandering) in adults with ADHD. Acta Neuropsychiatr. 2017 Dec; 29(6):330-336. PMID: 29151406.
    Citations:    Fields:    Translation:Humans
  14. Silverstein MJ, Faraone SV, Alperin S, Biederman J, Spencer TJ, Adler LA. How Informative Are Self-Reported Adult Attention-Deficit/Hyperactivity Disorder Symptoms? An Examination of the Agreement Between the Adult Attention-Deficit/Hyperactivity Disorder Self-Report Scale V1.1 and Adult Attention-Deficit/Hyperactivity Disorder Investigator Symptom Rating Scale. J Child Adolesc Psychopharmacol. 2018 06; 28(5):339-349. PMID: 29172673.
    Citations: 1     Fields:    
  15. Ustun B, Adler LA, Rudin C, Faraone SV, Spencer TJ, Berglund P, Gruber MJ, Kessler RC. The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5. JAMA Psychiatry. 2017 05 01; 74(5):520-526. PMID: 28384801.
    Citations: 4     Fields:    Translation:Humans
  16. Adler LA, Faraone SV, Spencer TJ, Berglund P, Alperin S, Kessler RC. The structure of adult ADHD. Int J Methods Psychiatr Res. 2017 03; 26(1). PMID: 28211596.
    Citations: 1     Fields:    Translation:Humans
  17. Spencer AE, Marin MF, Milad MR, Spencer TJ, Bogucki OE, Pope AL, Plasencia N, Hughes B, Pace-Schott EF, Fitzgerald M, Uchida M, Biederman J. Abnormal fear circuitry in Attention Deficit Hyperactivity Disorder: A controlled magnetic resonance imaging study. Psychiatry Res Neuroimaging. 2017 Apr 30; 262:55-62. PMID: 28235692.
    Citations:    
  18. Zhu J, Fan F, McCarthy DM, Zhang L, Cannon EN, Spencer TJ, Biederman J, Bhide PG. A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes. Int J Dev Neurosci. 2017 May; 58:26-34. PMID: 28179105.
    Citations: 2     Fields:    Translation:Animals
  19. Biederman J, Fitzgerald M, Spencer TJ, Bhide PG, McCarthy DM, Woodworth KY, Saunders A, Faraone SV. Is Paternal Smoking at Conception a Risk for ADHD? A Controlled Study in Youth With and Without ADHD. J Atten Disord. 2017 Feb 01; 1087054717690809. PMID: 28152645.
    Citations: 1     Fields:    
  20. Biederman J, Fried R, Tarko L, Surman C, Spencer T, Pope A, Grossman R, McDermott K, Woodworth KY, Faraone SV. Memantine in the Treatment of Executive Function Deficits in Adults With ADHD. J Atten Disord. 2017 02; 21(4):343-352. PMID: 24970718.
    Citations: 3     Fields:    Translation:HumansCells
  21. Spencer AE, Faraone SV, Bogucki OE, Pope AL, Uchida M, Milad MR, Spencer TJ, Woodworth KY, Biederman J. Examining the association between posttraumatic stress disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. J Clin Psychiatry. 2016 Jan; 77(1):72-83. PMID: 26114394.
    Citations: 2     Fields:    Translation:Humans
  22. Mattfeld AT, Whitfield-Gabrieli S, Biederman J, Spencer T, Brown A, Fried R, Gabrieli JD. Dissociation of working memory impairments and attention-deficit/hyperactivity disorder in the brain. Neuroimage Clin. 2016; 10:274-82. PMID: 26900567.
    Citations: 5     Fields:    Translation:Humans
  23. Biederman J, Feinberg L, Chan J, Adeyemo BO, Woodworth KY, Panis W, McGrath N, Bhatnagar S, Spencer TJ, Uchida M, Kenworthy T, Grossman R, Zafonte R, Faraone SV. Mild Traumatic Brain Injury and Attention-Deficit Hyperactivity Disorder in Young Student Athletes. J Nerv Ment Dis. 2015 Nov; 203(11):813-9. PMID: 26461480.
    Citations: 6     Fields:    Translation:Humans
  24. Uchida M, Spencer TJ, Faraone SV, Biederman J. Adult Outcome of ADHD: An Overview of Results From the MGH Longitudinal Family Studies of Pediatrically and Psychiatrically Referred Youth With and Without ADHD of Both Sexes. J Atten Disord. 2018 04; 22(6):523-534. PMID: 26396145.
    Citations: 11     Fields:    
  25. Biederman J, Chan J, Faraone SV, Woodworth KY, Spencer TJ, Wozniak JR. A Familial Risk Analysis of Emotional Dysregulation: A Controlled Study. J Atten Disord. 2018 07; 22(9):848-854. PMID: 26220788.
    Citations:    Fields:    
  26. Biederman J, Martelon M, Woodworth KY, Spencer TJ, Faraone SV. Is Maternal Smoking During Pregnancy a Risk Factor for Cigarette Smoking in Offspring? A Longitudinal Controlled Study of ADHD Children Grown Up. J Atten Disord. 2017 Oct; 21(12):975-985. PMID: 25416463.
    Citations: 3     Fields:    Translation:Humans
  27. Spencer TJ, Faraone SV, Tarko L, McDermott K, Biederman J. Attention-deficit/hyperactivity disorder and adverse health outcomes in adults. J Nerv Ment Dis. 2014 Oct; 202(10):725-31. PMID: 25211634.
    Citations: 8     Fields:    Translation:Humans
  28. Adeyemo BO, Biederman J, Zafonte R, Kagan E, Spencer TJ, Uchida M, Kenworthy T, Spencer AE, Faraone SV. Mild traumatic brain injury and ADHD: a systematic review of the literature and meta-analysis. J Atten Disord. 2014 Oct; 18(7):576-84. PMID: 25047040.
    Citations: 8     Fields:    Translation:Humans
  29. Mattfeld AT, Gabrieli JD, Biederman J, Spencer T, Brown A, Kotte A, Kagan E, Whitfield-Gabrieli S. Brain differences between persistent and remitted attention deficit hyperactivity disorder. Brain. 2014 Sep; 137(Pt 9):2423-8. PMID: 24916335.
    Citations: 15     Fields:    Translation:Humans
  30. Uchida M, Faraone SV, Martelon M, Kenworthy T, Woodworth KY, Spencer TJ, Wozniak JR, Biederman J. Further evidence that severe scores in the aggression/anxiety-depression/attention subscales of child behavior checklist (severe dysregulation profile) can screen for bipolar disorder symptomatology: a conditional probability analysis. J Affect Disord. 2014 Aug; 165:81-6. PMID: 24882182.
    Citations: 3     Fields:    Translation:Humans
  31. Antshel KM, Biederman J, Spencer TJ, Faraone SV. The Neuropsychological Profile of Comorbid Post-Traumatic Stress Disorder in Adult ADHD. J Atten Disord. 2016 12; 20(12):1047-1055. PMID: 24567364.
    Citations:    Fields:    Translation:Humans
  32. Zhu J, Lee KP, Spencer TJ, Biederman J, Bhide PG. Transgenerational transmission of hyperactivity in a mouse model of ADHD. J Neurosci. 2014 Feb 19; 34(8):2768-73. PMID: 24553919.
    Citations: 14     Fields:    Translation:Animals
  33. Makris N, Liang L, Biederman J, Valera EM, Brown AB, Petty C, Spencer TJ, Faraone SV, Seidman LJ. Toward Defining the Neural Substrates of ADHD: A Controlled Structural MRI Study in Medication-Naïve Adults. J Atten Disord. 2015 Nov; 19(11):944-53. PMID: 24189200.
    Citations: 10     Fields:    Translation:HumansCells
  34. Spencer TJ, Brown A, Seidman LJ, Valera EM, Makris N, Lomedico A, Faraone SV, Biederman J. Effect of psychostimulants on brain structure and function in ADHD: a qualitative literature review of magnetic resonance imaging-based neuroimaging studies. J Clin Psychiatry. 2013 Sep; 74(9):902-17. PMID: 24107764.
    Citations: 20     Fields:    Translation:Humans
  35. Biederman J, Wozniak J, Martelon MK, Spencer TJ, Woodworth Y, Joshi G, Spencer A, Uchida M, Kotte A, Faraone SV. Can pediatric bipolar-I disorder be diagnosed in the context of posttraumatic stress disorder? A familial risk analysis. Psychiatry Res. 2013 Aug 15; 208(3):215-24. PMID: 23790757.
    Citations: 1     Fields:    Translation:Humans
  36. Biederman J, Petty C, Spencer TJ, Woodworth KY, Bhide P, Zhu J, Faraone SV. Is ADHD a risk for posttraumatic stress disorder (PTSD)? Results from a large longitudinal study of referred children with and without ADHD. World J Biol Psychiatry. 2014 Jan; 15(1):49-55. PMID: 23607442.
    Citations: 6     Fields:    Translation:Humans
  37. Surman CB, Biederman J, Spencer T, Miller CA, Petty CR, Faraone SV. Neuropsychological Deficits Are Not Predictive of Deficient Emotional Self-Regulation in Adults With ADHD. J Atten Disord. 2015 Dec; 19(12):1046-53. PMID: 23503813.
    Citations: 4     Fields:    Translation:Humans
  38. Antshel KM, Kaul P, Biederman J, Spencer TJ, Hier BO, Hendricks K, Faraone SV. Posttraumatic stress disorder in adult attention-deficit/hyperactivity disorder: clinical features and familial transmission. J Clin Psychiatry. 2013 Mar; 74(3):e197-204. PMID: 23561240.
    Citations: 6     Fields:    Translation:Humans
  39. Surman CB, Biederman J, Spencer T, Miller CA, McDermott KM, Faraone SV. Understanding deficient emotional self-regulation in adults with attention deficit hyperactivity disorder: a controlled study. Atten Defic Hyperact Disord. 2013 Sep; 5(3):273-81. PMID: 23413201.
    Citations: 10     Fields:    Translation:Humans
  40. Spencer TJ, Biederman J, Faraone SV, Madras BK, Bonab AA, Dougherty DD, Batchelder H, Clarke A, Fischman AJ. Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects. Biol Psychiatry. 2013 Jul 15; 74(2):84-9. PMID: 23273726.
    Citations: 17     Fields:    Translation:HumansCells
  41. Biederman J, Martelon M, Faraone SV, Woodworth KY, Spencer TJ, Wozniak JR. Personal and familial correlates of bipolar (BP)-I disorder in children with a diagnosis of BP-I disorder with a positive child behavior checklist (CBCL)-severe dysregulation profile: a controlled study. J Affect Disord. 2013 May; 147(1-3):164-70. PMID: 23164462.
    Citations: 7     Fields:    Translation:Humans
  42. Hammerness P, Joshi G, Doyle R, Georgiopoulos A, Geller D, Spencer T, Petty CR, Faraone SV, Biederman J. Do stimulants reduce the risk for cigarette smoking in youth with attention-deficit hyperactivity disorder? A prospective, long-term, open-label study of extended-release methylphenidate. J Pediatr. 2013 Jan; 162(1):22-7.e2. PMID: 22878114.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  43. Zhu J, Zhang X, Xu Y, Spencer TJ, Biederman J, Bhide PG. Prenatal nicotine exposure mouse model showing hyperactivity, reduced cingulate cortex volume, reduced dopamine turnover, and responsiveness to oral methylphenidate treatment. J Neurosci. 2012 Jul 04; 32(27):9410-8. PMID: 22764249.
    Citations: 22     Fields:    Translation:Animals
  44. Biederman J, Spencer TJ, Petty C, Hyder LL, O'Connor KB, Surman CB, Faraone SV. Longitudinal course of deficient emotional self-regulation CBCL profile in youth with ADHD: prospective controlled study. Neuropsychiatr Dis Treat. 2012; 8:267-76. PMID: 22848182.
    Citations: 13     
  45. Spencer TJ, Madras BK, Fischman AJ, Krause J, La Fougère C. Striatal dopamine transporter binding in adults with ADHD. Am J Psychiatry. 2012 Jun; 169(6):665; author reply 666. PMID: 22684601.
    Citations: 2     Fields:    Translation:Humans
  46. Makris N, Seidman LJ, Brown A, Valera EM, Kaiser JR, Petty CR, Liang L, Aleardi M, Boriel D, Henderson CS, Giddens M, Faraone SV, Spencer TJ, Biederman J. Further understanding of the comorbidity between Attention-Deficit/Hyperactivity Disorder and bipolar disorder in adults: an MRI study of cortical thickness. Psychiatry Res. 2012 Apr 30; 202(1):1-11. PMID: 22640688.
    Citations: 2     Fields:    Translation:Humans
  47. Adler LA, Shaw DM, Spencer TJ, Newcorn JH, Hammerness P, Sitt DJ, Minerly C, Davidow JV, Faraone SV. Preliminary examination of the reliability and concurrent validity of the attention-deficit/hyperactivity disorder self-report scale v1.1 symptom checklist to rate symptoms of attention-deficit/hyperactivity disorder in adolescents. J Child Adolesc Psychopharmacol. 2012 Jun; 22(3):238-44. PMID: 22537184.
    Citations: 10     Fields:    Translation:Humans
  48. Biederman J, Petty CR, Day H, Goldin RL, Spencer T, Faraone SV, Surman CB, Wozniak J. Severity of the aggression/anxiety-depression/attention child behavior checklist profile discriminates between different levels of deficits in emotional regulation in youth with attention-deficit hyperactivity disorder. J Dev Behav Pediatr. 2012 Apr; 33(3):236-43. PMID: 22278125.
    Citations: 25     Fields:    Translation:Humans
  49. Surman CB, Hammerness PG, Petty C, Spencer T, Doyle R, Napolean S, Chu N, Yorks D, Biederman J. A pilot open label prospective study of memantine monotherapy in adults with ADHD. World J Biol Psychiatry. 2013 May; 14(4):291-8. PMID: 22436083.
    Citations: 6     Fields:    Translation:Humans
  50. Spencer TJ, Biederman J, Martin JM, Moorehead TM, Mirto T, Clarke A, Batchelder H, Faraone SV. Importance of pharmacokinetic profile and timing of coadministration of short- and long-acting formulations of methylphenidate on patterns of subjective responses and abuse potential. Postgrad Med. 2012 Jan; 124(1):166-73. PMID: 22314126.
    Citations: 3     Fields:    Translation:Humans
  51. Spencer TJ, Bonab AA, Dougherty DD, Mirto T, Martin J, Clarke A, Fischman AJ. Understanding the central pharmacokinetics of spheroidal oral drug absorption system (SODAS) dexmethylphenidate: a positron emission tomography study of dopamine transporter receptor occupancy measured with C-11 altropane. J Clin Psychiatry. 2012 Mar; 73(3):346-52. PMID: 22154896.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  52. Spencer TJ, Faraone SV, Surman CB, Petty C, Clarke A, Batchelder H, Wozniak J, Biederman J. Toward defining deficient emotional self-regulation in children with attention-deficit/hyperactivity disorder using the Child Behavior Checklist: a controlled study. Postgrad Med. 2011 Sep; 123(5):50-9. PMID: 21904086.
    Citations: 16     Fields:    Translation:Humans
  53. Adler LA, Shaw DM, Spencer TJ, Newcorn JH, Sitt DJ, Minerly AE, Davidow JV, Faraone SV. Preliminary reliability and validity of a new time-sensitive ADHD symptom scale in adolescents with ADHD. Postgrad Med. 2011 Sep; 123(5):7-13. PMID: 21904082.
    Citations:    Fields:    Translation:Humans
  54. Biederman J, Mick E, Spencer T, Surman C, Faraone SV. Is response to OROS-methylphenidate treatment moderated by treatment with antidepressants or psychiatric comorbidity? A secondary analysis from a large randomized double blind study of adults with ADHD. CNS Neurosci Ther. 2012 Feb; 18(2):126-32. PMID: 22070421.
    Citations: 3     Fields:    Translation:HumansCells
  55. Brown AB, Biederman J, Valera E, Makris N, Doyle A, Whitfield-Gabrieli S, Mick E, Spencer T, Faraone S, Seidman L. Relationship of DAT1 and adult ADHD to task-positive and task-negative working memory networks. Psychiatry Res. 2011 Jul 30; 193(1):7-16. PMID: 21596533.
    Citations: 18     Fields:    Translation:HumansCells
  56. Faraone SV, Spencer TJ, Kollins SH, Glatt SJ, Goodman D. Dose response effects of lisdexamfetamine dimesylate treatment in adults with ADHD: an exploratory study. J Atten Disord. 2012 Feb; 16(2):118-27. PMID: 21527575.
    Citations: 2     Fields:    Translation:Humans
  57. Zhu J, Spencer TJ, Liu-Chen LY, Biederman J, Bhide PG. Methylphenidate and µ opioid receptor interactions: a pharmacological target for prevention of stimulant abuse. Neuropharmacology. 2011 Jul-Aug; 61(1-2):283-92. PMID: 21545805.
    Citations: 6     Fields:    Translation:AnimalsCells
  58. Surman CB, Biederman J, Spencer T, Yorks D, Miller CA, Petty CR, Faraone SV. Deficient emotional self-regulation and adult attention deficit hyperactivity disorder: a family risk analysis. Am J Psychiatry. 2011 Jun; 168(6):617-23. PMID: 21498464.
    Citations: 19     Fields:    Translation:Humans
  59. Biederman J, Mick E, Fried R, Wilner N, Spencer TJ, Faraone SV. Are stimulants effective in the treatment of executive function deficits? Results from a randomized double blind study of OROS-methylphenidate in adults with ADHD. Eur Neuropsychopharmacol. 2011 Jul; 21(7):508-15. PMID: 21303732.
    Citations: 6     Fields:    Translation:Humans
  60. Adler LA, Shaw DM, Spencer TJ, Newcorn JH, Sitt DJ, Morrill M, Davidow JV, Glatt SJ, Faraone SV. Reliability and validity of the Time-Sensitive ADHD Symptom Scale in adults. Compr Psychiatry. 2011 Nov-Dec; 52(6):769-73. PMID: 21306705.
    Citations:    Fields:    Translation:Humans
  61. Trzepacz PT, Spencer TJ, Zhang S, Bangs ME, Witte MM, Desaiah D. Effect of atomoxetine on Tanner stage sexual development in children and adolescents with attention deficit/hyperactivity disorder: 18-month results from a double-blind, placebo-controlled trial. Curr Med Res Opin. 2011; 27 Suppl 2:45-52. PMID: 21973230.
    Citations: 2     Fields:    Translation:Humans
  62. Seidman LJ, Biederman J, Liang L, Valera EM, Monuteaux MC, Brown A, Kaiser J, Spencer T, Faraone SV, Makris N. Gray matter alterations in adults with attention-deficit/hyperactivity disorder identified by voxel based morphometry. Biol Psychiatry. 2011 May 01; 69(9):857-66. PMID: 21183160.
    Citations: 41     Fields:    Translation:HumansCells
  63. Spencer TJ, Madras BK, Bonab AA, Dougherty DD, Clarke A, Mirto T, Martin J, Fischman AJ. A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride. Biol Psychiatry. 2010 Nov 15; 68(10):964-70. PMID: 21035624.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  64. Biederman J, Spencer TJ, Monuteaux MC, Faraone SV. A naturalistic 10-year prospective study of height and weight in children with attention-deficit hyperactivity disorder grown up: sex and treatment effects. J Pediatr. 2010 Oct; 157(4):635-40, 640.e1. PMID: 20605163.
    Citations: 22     Fields:    Translation:Humans
  65. Biederman J, Mick E, Surman C, Doyle R, Hammerness P, Kotarski M, Spencer T. A randomized, 3-phase, 34-week, double-blind, long-term efficacy study of osmotic-release oral system-methylphenidate in adults with attention-deficit/hyperactivity disorder. J Clin Psychopharmacol. 2010 Oct; 30(5):549-53. PMID: 20814332.
    Citations: 21     Fields:    Translation:HumansCellsCTClinical Trials
  66. Wilens TE, Spencer TJ. Understanding attention-deficit/hyperactivity disorder from childhood to adulthood. Postgrad Med. 2010 Sep; 122(5):97-109. PMID: 20861593.
    Citations: 24     Fields:    Translation:Humans
  67. Valera EM, Spencer RM, Zeffiro TA, Makris N, Spencer TJ, Faraone SV, Biederman J, Seidman LJ. Neural substrates of impaired sensorimotor timing in adult attention-deficit/hyperactivity disorder. Biol Psychiatry. 2010 Aug 15; 68(4):359-67. PMID: 20619827.
    Citations: 30     Fields:    Translation:Humans
  68. Surman CB, Monuteaux MC, Petty CR, Faraone SV, Spencer TJ, Chu NF, Biederman J. Representativeness of participants in a clinical trial for attention-deficit/hyperactivity disorder? Comparison with adults from a large observational study. J Clin Psychiatry. 2010 Dec; 71(12):1612-6. PMID: 20816030.
    Citations: 12     Fields:    Translation:Humans
  69. Spencer TJ, Mick E, Surman CB, Hammerness P, Doyle R, Aleardi M, Kotarski M, Williams CG, Biederman J. A randomized, single-blind, substitution study of OROS methylphenidate (Concerta) in ADHD adults receiving immediate release methylphenidate. J Atten Disord. 2011 May; 15(4):286-94. PMID: 20495161.
    Citations: 6     Fields:    Translation:Humans
  70. Rios JJ, Fleming JG, Bryant UK, Carter CN, Huber JC, Long MT, Spencer TE, Adelson DL. OAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horses. PLoS One. 2010 May 07; 5(5):e10537. PMID: 20479874.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  71. Wilens TE, Prince JB, Waxmonsky J, Doyle R, Spencer T, Martelon M, Evans M. An Open Trial of Sustained Release Bupropion for Attention-Deficit/Hyperactivity Disorder in Adults with ADHD plus Substance Use Disorders. J ADHD Relat Disord. 2010 Apr 01; 1(3):25-35. PMID: 22500195.
    Citations: 4     
  72. Brown AB, Biederman J, Valera EM, Doyle AE, Bush G, Spencer T, Monuteaux MC, Mick E, Whitfield-Gabrieli S, Makris N, LaViolette PS, Oscar-Berman M, Faraone SV, Seidman LJ. Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 05; 153B(2):365-375. PMID: 19676101.
    Citations: 18     Fields:    Translation:Humans
  73. Spencer TJ, Bonab AA, Dougherty DD, Martin J, McDonnell T, Fischman AJ. A PET study examining pharmacokinetics and dopamine transporter occupancy of two long-acting formulations of methylphenidate in adults. Int J Mol Med. 2010 Feb; 25(2):261-5. PMID: 20043136.
    Citations: 2     Fields:    Translation:Humans
  74. Biederman J, Petty CR, Monuteaux MC, Fried R, Byrne D, Mirto T, Spencer T, Wilens TE, Faraone SV. Adult psychiatric outcomes of girls with attention deficit hyperactivity disorder: 11-year follow-up in a longitudinal case-control study. Am J Psychiatry. 2010 Apr; 167(4):409-17. PMID: 20080984.
    Citations: 51     Fields:    Translation:Humans
  75. Faraone SV, Spencer TJ, Kollins SH, Glatt SJ. Effects of lisdexamfetamine dimesylate treatment for ADHD on growth. J Am Acad Child Adolesc Psychiatry. 2010 Jan; 49(1):24-32. PMID: 20215923.
    Citations: 10     Fields:    Translation:Humans
  76. Bott RC, Ashley RL, Henkes LE, Antoniazzi AQ, Bruemmer JE, Niswender GD, Bazer FW, Spencer TE, Smirnova NP, Anthony RV, Hansen TR. Uterine vein infusion of interferon tau (IFNT) extends luteal life span in ewes. Biol Reprod. 2010 Apr; 82(4):725-35. PMID: 20042537.
    Citations: 7     Fields:    Translation:AnimalsCells
  77. Brown TE, Holdnack J, Saylor K, Adler L, Spencer T, Williams DW, Padival AK, Schuh K, Trzepacz PT, Kelsey D. Effect of atomoxetine on executive function impairments in adults with ADHD. J Atten Disord. 2011 Feb; 15(2):130-8. PMID: 20026871.
    Citations: 10     Fields:    Translation:Humans
  78. Biederman J, Petty CR, Ten Haagen KS, Small J, Doyle AE, Spencer T, Mick E, Monuteaux MC, Smoller JW, Faraone SV. Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorder. Psychiatry Res. 2009 Dec 30; 170(2-3):199-203. PMID: 19906444.
    Citations: 13     Fields:    Translation:HumansCells
  79. Wilens TE, Biederman J, Faraone SV, Martelon M, Westerberg D, Spencer TJ. Presenting ADHD symptoms, subtypes, and comorbid disorders in clinically referred adults with ADHD. J Clin Psychiatry. 2009 Nov; 70(11):1557-62. PMID: 20031097.
    Citations: 30     Fields:    Translation:Humans
  80. Spencer TJ, Greenbaum M, Ginsberg LD, Murphy WR. Safety and effectiveness of coadministration of guanfacine extended release and psychostimulants in children and adolescents with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2009 Oct; 19(5):501-10. PMID: 19877974.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  81. Spencer TJ, Adler LA, Saylor KE, Brown TE, Holdnack JA, Schuh KJ, Trzepacz PT, Kelsey DK. Validation of the adult ADHD investigator symptom rating scale (AISRS). J Atten Disord. 2010 Jul; 14(1):57-68. PMID: 19794135.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  82. Childress AC, Spencer T, Lopez F, Gerstner O, Thulasiraman A, Muniz R, Post A. Efficacy and safety of dexmethylphenidate extended-release capsules administered once daily to children with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2009 Aug; 19(4):351-61. PMID: 19702487.
    Citations: 4     Fields:    Translation:Humans
  83. Balcioglu A, Ren JQ, McCarthy D, Spencer TJ, Biederman J, Bhide PG. Plasma and brain concentrations of oral therapeutic doses of methylphenidate and their impact on brain monoamine content in mice. Neuropharmacology. 2009 Dec; 57(7-8):687-93. PMID: 19631228.
    Citations: 15     Fields:    Translation:Animals
  84. Biederman J, Monuteaux MC, Spencer T, Wilens TE, Faraone SV. Do stimulants protect against psychiatric disorders in youth with ADHD? A 10-year follow-up study. Pediatrics. 2009 Jul; 124(1):71-8. PMID: 19564285.
    Citations: 40     Fields:    Translation:Humans
  85. Adler LA, Zimmerman B, Starr HL, Silber S, Palumbo J, Orman C, Spencer T. Efficacy and safety of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled, double-blind, parallel group, dose-escalation study. J Clin Psychopharmacol. 2009 Jun; 29(3):239-47. PMID: 19440077.
    Citations: 28     Fields:    Translation:Humans
  86. Biederman J, Petty CR, Wilens TE, Spencer T, Henin A, Faraone SV, Mick E, Monuteaux MC, Kenealy D, Mirto T, Wozniak J. Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorder. Bipolar Disord. 2009 May; 11(3):298-306. PMID: 19419387.
    Citations: 3     Fields:    Translation:Humans
  87. Hammerness P, Wilens T, Mick E, Spencer T, Doyle R, McCreary M, Becker J, Biederman J. Cardiovascular effects of longer-term, high-dose OROS methylphenidate in adolescents with attention deficit hyperactivity disorder. J Pediatr. 2009 Jul; 155(1):84-9, 89.e1. PMID: 19394037.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  88. Adler LA, Spencer T, McGough JJ, Jiang H, Muniz R. Long-term effectiveness and safety of dexmethylphenidate extended-release capsules in adult ADHD. J Atten Disord. 2009 Mar; 12(5):449-59. PMID: 19218542.
    Citations: 17     Fields:    Translation:Humans
  89. Adler LA, Spencer T, Brown TE, Holdnack J, Saylor K, Schuh K, Trzepacz PT, Williams DW, Kelsey D. Once-daily atomoxetine for adult attention-deficit/hyperactivity disorder: a 6-month, double-blind trial. J Clin Psychopharmacol. 2009 Feb; 29(1):44-50. PMID: 19142107.
    Citations: 29     Fields:    Translation:Humans
  90. Donnelly C, Bangs M, Trzepacz P, Jin L, Zhang S, Witte MM, Ball SG, Spencer TJ. Safety and tolerability of atomoxetine over 3 to 4 years in children and adolescents with ADHD. J Am Acad Child Adolesc Psychiatry. 2009 Feb; 48(2):176-85. PMID: 20040824.
    Citations: 19     Fields:    Translation:Humans
  91. Spencer TJ. Issues in the management of patients with complex attention-deficit hyperactivity disorder symptoms. CNS Drugs. 2009; 23 Suppl 1:9-20. PMID: 19621974.
    Citations: 5     Fields:    Translation:Humans
  92. Spencer TJ. Toward a new understanding of attention-deficit hyperactivity disorder: advances in research and treatment. CNS Drugs. 2009; 23 Suppl 1:5-8. PMID: 19621973.
    Citations: 2     Fields:    Translation:Humans
  93. Monuteaux MC, Seidman LJ, Faraone SV, Makris N, Spencer T, Valera E, Brown A, Bush G, Doyle AE, Hughes S, Helliesen M, Mick E, Biederman J. A preliminary study of dopamine D4 receptor genotype and structural brain alterations in adults with ADHD. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1436-41. PMID: 18951431.
    Citations: 11     Fields:    Translation:Humans
  94. Spencer TJ, Landgraf JM, Adler LA, Weisler RH, Anderson CS, Youcha SH. Attention-deficit/hyperactivity disorder-specific quality of life with triple-bead mixed amphetamine salts (SPD465) in adults: results of a randomized, double-blind, placebo-controlled study. J Clin Psychiatry. 2008 Nov; 69(11):1766-75. PMID: 19026251.
    Citations: 7     Fields:    Translation:Humans
  95. Mick E, Kim JW, Biederman J, Wozniak J, Wilens T, Spencer T, Smoller JW, Faraone SV. Family based association study of pediatric bipolar disorder and the dopamine transporter gene (SLC6A3). Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 05; 147B(7):1182-5. PMID: 18361424.
    Citations: 17     Fields:    Translation:Humans
  96. Spencer TJ. Adult ADHD: diversion and misuse of medications. CNS Spectr. 2008 Oct; 13(10 Suppl 15):9-13. PMID: 18955949.
    Citations:    Fields:    Translation:Humans
  97. Spencer TJ, Adler LA, Weisler RH, Youcha SH. Triple-bead mixed amphetamine salts (SPD465), a novel, enhanced extended-release amphetamine formulation for the treatment of adults with ADHD: a randomized, double-blind, multicenter, placebo-controlled study. J Clin Psychiatry. 2008 Sep; 69(9):1437-48. PMID: 19012813.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  98. Spencer TJ. Neurobiology and genetics of ADHD in adults. CNS Spectr. 2008 Sep; 13(9 Suppl 13):5-7. PMID: 18849903.
    Citations: 2     Fields:    Translation:Humans
  99. Faraone SV, Biederman J, Morley CP, Spencer TJ. Effect of stimulants on height and weight: a review of the literature. J Am Acad Child Adolesc Psychiatry. 2008 Sep; 47(9):994-1009. PMID: 18580502.
    Citations: 53     Fields:    Translation:Humans
  100. Spencer TJ. The epidemiology of adult ADHD. CNS Spectr. 2008 Aug; 13(8 Suppl 12):6-8. PMID: 18704029.
    Citations:    Fields:    Translation:Humans
  101. Dunlap KA, Erikson DW, Burghardt RC, White FJ, Reed KM, Farmer JL, Spencer TE, Magness RR, Bazer FW, Bayless KJ, Johnson GA. Progesterone and placentation increase secreted phosphoprotein one (SPP1 or osteopontin) in uterine glands and stroma for histotrophic and hematotrophic support of ovine pregnancy. Biol Reprod. 2008 Nov; 79(5):983-90. PMID: 18667748.
    Citations:    
  102. Spencer TJ. Treatment of adult ADHD and comorbid depression. CNS Spectr. 2008 May; 13(5 Suppl 8):14-6. PMID: 18567134.
    Citations: 1     Fields:    Translation:Humans
  103. Adler LA, Spencer TJ, Williams DW, Moore RJ, Michelson D. Long-term, open-label safety and efficacy of atomoxetine in adults with ADHD: final report of a 4-year study. J Atten Disord. 2008 Nov; 12(3):248-53. PMID: 18448861.
    Citations: 17     Fields:    Translation:Humans
  104. Biederman J, Ball SW, Monuteaux MC, Mick E, Spencer TJ, McCreary M, Cote M, Faraone SV. New insights into the comorbidity between ADHD and major depression in adolescent and young adult females. J Am Acad Child Adolesc Psychiatry. 2008 Apr; 47(4):426-34. PMID: 18388760.
    Citations: 45     Fields:    Translation:Humans
  105. Biederman J, Spencer TJ. Psychopharmacological interventions. Child Adolesc Psychiatr Clin N Am. 2008 Apr; 17(2):439-58, xi. PMID: 18295155.
    Citations: 7     Fields:    Translation:Humans
  106. Biederman J, Monuteaux MC, Spencer T, Wilens TE, Macpherson HA, Faraone SV. Stimulant therapy and risk for subsequent substance use disorders in male adults with ADHD: a naturalistic controlled 10-year follow-up study. Am J Psychiatry. 2008 May; 165(5):597-603. PMID: 18316421.
    Citations: 44     Fields:    Translation:Humans
  107. Biederman J, Petty CR, Doyle AE, Spencer T, Henderson CS, Marion B, Fried R, Faraone SV. Stability of executive function deficits in girls with ADHD: a prospective longitudinal followup study into adolescence. Dev Neuropsychol. 2008; 33(1):44-61. PMID: 18443969.
    Citations: 15     Fields:    Translation:Humans
  108. Bush G, Spencer TJ, Holmes J, Shin LM, Valera EM, Seidman LJ, Makris N, Surman C, Aleardi M, Mick E, Biederman J. Functional magnetic resonance imaging of methylphenidate and placebo in attention-deficit/hyperactivity disorder during the multi-source interference task. Arch Gen Psychiatry. 2008 Jan; 65(1):102-14. PMID: 18180434.
    Citations: 58     Fields:    Translation:Humans
  109. Biederman J, Mick E, Spencer T, Dougherty M, Aleardi M, Wozniak J. A prospective open-label treatment trial of ziprasidone monotherapy in children and adolescents with bipolar disorder. Bipolar Disord. 2007 Dec; 9(8):888-94. PMID: 18076539.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  110. Adler LA, Faraone SV, Spencer TJ, Michelson D, Reimherr FW, Glatt SJ, Marchant BK, Biederman J. The reliability and validity of self- and investigator ratings of ADHD in adults. J Atten Disord. 2008 May; 11(6):711-9. PMID: 18025250.
    Citations: 18     Fields:    Translation:Humans
  111. Adler LA, Spencer TJ, Levine LR, Ramsey JL, Tamura R, Kelsey D, Ball SG, Allen AJ, Biederman J. Functional outcomes in the treatment of adults with ADHD. J Atten Disord. 2008 May; 11(6):720-7. PMID: 17968028.
    Citations: 17     Fields:    Translation:Humans
  112. Spencer TJ, Sallee FR, Gilbert DL, Dunn DW, McCracken JT, Coffey BJ, Budman CL, Ricardi RK, Leonard HL, Allen AJ, Milton DR, Feldman PD, Kelsey DK, Geller DA, Linder SL, Lewis DW, Winner PK, Kurlan RM, Mintz M. Atomoxetine treatment of ADHD in children with comorbid Tourette syndrome. J Atten Disord. 2008 Jan; 11(4):470-81. PMID: 17934184.
    Citations: 21     Fields:    Translation:Humans
  113. Mick E, Faraone SV, Spencer T, Zhang HF, Biederman J. Assessing the validity of the Quality of Life Enjoyment and Satisfaction Questionnaire Short Form in adults with ADHD. J Atten Disord. 2008 Jan; 11(4):504-9. PMID: 17934183.
    Citations: 16     Fields:    Translation:Humans
  114. Spencer TJ, Kratochvil CJ, Sangal RB, Saylor KE, Bailey CE, Dunn DW, Geller DA, Casat CD, Lipetz RS, Jain R, Newcorn JH, Ruff DD, Feldman PD, Furr AJ, Allen AJ. Effects of atomoxetine on growth in children with attention-deficit/hyperactivity disorder following up to five years of treatment. J Child Adolesc Psychopharmacol. 2007 Oct; 17(5):689-700. PMID: 17979588.
    Citations: 18     Fields:    Translation:Humans
  115. Biederman J, Mick EO, Surman C, Doyle R, Hammerness P, Michel E, Martin J, Spencer TJ. Comparative acute efficacy and tolerability of OROS and immediate release formulations of methylphenidate in the treatment of adults with attention-deficit/hyperactivity disorder. BMC Psychiatry. 2007 Sep 14; 7:49. PMID: 17868455.
    Citations: 10     Fields:    Translation:Humans
  116. Biederman J, Mick E, Spencer T, Doyle R, Joshi G, Hammerness P, Kotarski M, Aleardi M, Wozniak J. An open-label trial of aripiprazole monotherapy in children and adolescents with bipolar disorder. CNS Spectr. 2007 Sep; 12(9):683-9. PMID: 17805214.
    Citations: 19     Fields:    Translation:Humans
  117. Bangs ME, Emslie GJ, Spencer TJ, Ramsey JL, Carlson C, Bartky EJ, Busner J, Duesenberg DA, Harshawat P, Kaplan SL, Quintana H, Allen AJ, Sumner CR. Efficacy and safety of atomoxetine in adolescents with attention-deficit/hyperactivity disorder and major depression. J Child Adolesc Psychopharmacol. 2007 Aug; 17(4):407-20. PMID: 17822337.
    Citations: 29     Fields:    Translation:Humans
  118. Monuteaux MC, Spencer TJ, Faraone SV, Wilson AM, Biederman J. A randomized, placebo-controlled clinical trial of bupropion for the prevention of smoking in children and adolescents with attention-deficit/hyperactivity disorder. J Clin Psychiatry. 2007 Jul; 68(7):1094-101. PMID: 17685748.
    Citations: 14     Fields:    Translation:Humans
  119. Spencer TJ, Biederman J, Mick E. Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. J Pediatr Psychol. 2007 Jul; 32(6):631-42. PMID: 17556405.
    Citations: 93     Fields:    Translation:Humans
  120. Spencer TJ, Biederman J, Madras BK, Dougherty DD, Bonab AA, Livni E, Meltzer PC, Martin J, Rauch S, Fischman AJ. Further evidence of dopamine transporter dysregulation in ADHD: a controlled PET imaging study using altropane. Biol Psychiatry. 2007 Nov 01; 62(9):1059-61. PMID: 17511972.
    Citations: 32     Fields:    Translation:Humans
  121. Spencer TJ. Pharmacology of adult ADHD with stimulants. CNS Spectr. 2007 Apr; 12(4 Suppl 6):8-11. PMID: 17715564.
    Citations:    Fields:    Translation:Humans
  122. Biederman J, Petty CR, Fried R, Doyle AE, Mick E, Aleardi M, Monuteaux MC, Seidman LJ, Spencer T, Faneuil AR, Holmes L, Faraone SV. Utility of an abbreviated questionnaire to identify individuals with ADHD at risk for functional impairments. J Psychiatr Res. 2008 Mar; 42(4):304-10. PMID: 17335849.
    Citations: 4     Fields:    Translation:Humans
  123. Biederman J, Fried R, Monuteaux MC, Reimer B, Coughlin JF, Surman CB, Aleardi M, Dougherty M, Schoenfeld S, Spencer TJ, Faraone SV. A laboratory driving simulation for assessment of driving behavior in adults with ADHD: a controlled study. Ann Gen Psychiatry. 2007 Jan 30; 6:4. PMID: 17263888.
    Citations: 9     
  124. Faraone SV, Wilens TE, Petty C, Antshel K, Spencer T, Biederman J. Substance use among ADHD adults: implications of late onset and subthreshold diagnoses. Am J Addict. 2007; 16 Suppl 1:24-32; quiz 33-4. PMID: 17453604.
    Citations: 23     Fields:    Translation:Humans
  125. Kessler RC, Adler LA, Gruber MJ, Sarawate CA, Spencer T, Van Brunt DL. Validity of the World Health Organization Adult ADHD Self-Report Scale (ASRS) Screener in a representative sample of health plan members. Int J Methods Psychiatr Res. 2007; 16(2):52-65. PMID: 17623385.
    Citations: 75     Fields:    Translation:HumansPHPublic Health
  126. Spencer TJ, Biederman J, Mick E. Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. Ambul Pediatr. 2007 Jan-Feb; 7(1 Suppl):73-81. PMID: 17261486.
    Citations: 37     Fields:    Translation:Humans
  127. Mick E, Biederman J, Spencer T, Faraone SV, Sklar P. Absence of association with DAT1 polymorphism and response to methylphenidate in a sample of adults with ADHD. Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 05; 141B(8):890-4. PMID: 16917950.
    Citations: 12     Fields:    Translation:HumansCells
  128. White FJ, Burghardt RC, Hu J, Joyce MM, Spencer TE, Johnson GA. Secreted phosphoprotein 1 (osteopontin) is expressed by stromal macrophages in cyclic and pregnant endometrium of mice, but is induced by estrogen in luminal epithelium during conceptus attachment for implantation. Reproduction. 2006 Dec; 132(6):919-29. PMID: 17127752.
    Citations: 14     Fields:    Translation:AnimalsCells
  129. Perwien AR, Kratochvil CJ, Faries DE, Vaughan BS, Spencer T, Brown RT. Atomoxetine treatment in children and adolescents with attention-deficit hyperactivity disorder: what are the long-term health-related quality-of-life outcomes? J Child Adolesc Psychopharmacol. 2006 Dec; 16(6):713-24. PMID: 17201615.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  130. Spencer TJ, Adler LA, McGough JJ, Muniz R, Jiang H, Pestreich L. Efficacy and safety of dexmethylphenidate extended-release capsules in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2007 Jun 15; 61(12):1380-7. PMID: 17137560.
    Citations: 35     Fields:    Translation:Humans
  131. Biederman J, Spencer TJ, Newcorn JH, Gao H, Milton DR, Feldman PD, Witte MM. Effect of comorbid symptoms of oppositional defiant disorder on responses to atomoxetine in children with ADHD: a meta-analysis of controlled clinical trial data. Psychopharmacology (Berl). 2007 Jan; 190(1):31-41. PMID: 17093981.
    Citations: 23     Fields:    Translation:Humans
  132. Faraone SV, Biederman J, Spencer TJ, Aleardi M. Comparing the efficacy of medications for ADHD using meta-analysis. MedGenMed. 2006 Oct 05; 8(4):4. PMID: 17415287.
    Citations: 60     Fields:    Translation:Humans
  133. Biederman J, Spencer TJ, Wilens TE, Prince JB, Faraone SV. Treatment of ADHD with stimulant medications: response to Nissen perspective in the New England Journal of Medicine. J Am Acad Child Adolesc Psychiatry. 2006 Oct; 45(10):1147-50. PMID: 16840880.
    Citations: 7     Fields:    Translation:Humans
  134. Faraone SV, Biederman J, Spencer T, Mick E, Murray K, Petty C, Adamson JJ, Monuteaux MC. Diagnosing adult attention deficit hyperactivity disorder: are late onset and subthreshold diagnoses valid? Am J Psychiatry. 2006 Oct; 163(10):1720-9; quiz 1859. PMID: 17012682.
    Citations: 59     Fields:    Translation:Humans
  135. Wilens TE, Prince JB, Spencer TJ, Biederman J. Stimulants and sudden death: what is a physician to do? Pediatrics. 2006 Sep; 118(3):1215-9. PMID: 16951018.
    Citations: 16     Fields:    Translation:Humans
  136. Buitelaar JK, Michelson D, Danckaerts M, Gillberg C, Spencer TJ, Zuddas A, Faries DE, Zhang S, Biederman J. A randomized, double-blind study of continuation treatment for attention-deficit/hyperactivity disorder after 1 year. Biol Psychiatry. 2007 Mar 01; 61(5):694-9. PMID: 16893523.
    Citations: 19     Fields:    Translation:HumansPHPublic Health
  137. Madras BK, Xie Z, Lin Z, Jassen A, Panas H, Lynch L, Johnson R, Livni E, Spencer TJ, Bonab AA, Miller GM, Fischman AJ. Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro. J Pharmacol Exp Ther. 2006 Nov; 319(2):561-9. PMID: 16885432.
    Citations: 99     Fields:    Translation:Animals
  138. Weisler RH, Biederman J, Spencer TJ, Wilens TE, Faraone SV, Chrisman AK, Read SC, Tulloch SJ. Mixed amphetamine salts extended-release in the treatment of adult ADHD: a randomized, controlled trial. CNS Spectr. 2006 Aug; 11(8):625-39. PMID: 16871129.
    Citations: 36     Fields:    Translation:Humans
  139. Adler LA, Spencer T, Faraone SV, Kessler RC, Howes MJ, Biederman J, Secnik K. Validity of pilot Adult ADHD Self- Report Scale (ASRS) to Rate Adult ADHD symptoms. Ann Clin Psychiatry. 2006 Jul-Sep; 18(3):145-8. PMID: 16923651.
    Citations: 81     Fields:    Translation:Humans
  140. Biederman J, Gao H, Rogers AK, Spencer TJ. Comparison of parent and teacher reports of attention-deficit/hyperactivity disorder symptoms from two placebo-controlled studies of atomoxetine in children. Biol Psychiatry. 2006 Nov 15; 60(10):1106-10. PMID: 16806096.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  141. Anderson CM, Maas LC, Frederick Bd, Bendor JT, Spencer TJ, Livni E, Lukas SE, Fischman AJ, Madras BK, Renshaw PF, Kaufman MJ. Cerebellar vermis involvement in cocaine-related behaviors. Neuropsychopharmacology. 2006 Jun; 31(6):1318-26. PMID: 16237382.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  142. Biederman J, Monuteaux MC, Mick E, Spencer T, Wilens TE, Klein KL, Price JE, Faraone SV. Psychopathology in females with attention-deficit/hyperactivity disorder: a controlled, five-year prospective study. Biol Psychiatry. 2006 Nov 15; 60(10):1098-105. PMID: 16712802.
    Citations: 52     Fields:    Translation:Humans
  143. Biederman J, Mick E, Faraone SV, Wozniak J, Spencer T, Pandina G. Risperidone for the treatment of affective symptoms in children with disruptive behavior disorder: a post hoc analysis of data from a 6-week, multicenter, randomized, double-blind, parallel-arm study. Clin Ther. 2006 May; 28(5):794-800. PMID: 16861101.
    Citations: 6     Fields:    Translation:Humans
  144. Spencer TJ, Faraone SV, Biederman J, Lerner M, Cooper KM, Zimmerman B. Does prolonged therapy with a long-acting stimulant suppress growth in children with ADHD? J Am Acad Child Adolesc Psychiatry. 2006 May; 45(5):527-37. PMID: 16670649.
    Citations: 21     Fields:    Translation:Humans
  145. Biederman J, Mick E, Spencer T, Surman C, Hammerness P, Doyle R, Dougherty M, Aleardi M, Schweitzer K. An open-label trial of OROS methylphenidate in adults with late-onset ADHD. CNS Spectr. 2006 May; 11(5):390-6. PMID: 16641844.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  146. Wilens TE, Zusman RM, Hammerness PG, Podolski A, Whitley J, Spencer TJ, Gignac M, Biederman J. An open-label study of the tolerability of mixed amphetamine salts in adults with attention-deficit/hyperactivity disorder and treated primary essential hypertension. J Clin Psychiatry. 2006 May; 67(5):696-702. PMID: 16841618.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  147. Biederman J, Mick E, Faraone S, Hammerness P, Surman C, Harpold T, Dougherty M, Aleardi M, Spencer T. A double-blind comparison of galantamine hydrogen bromide and placebo in adults with attention-deficit/hyperactivity disorder: a pilot study. J Clin Psychopharmacol. 2006 Apr; 26(2):163-6. PMID: 16633145.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  148. Biederman J, Faraone SV, Spencer TJ, Mick E, Monuteaux MC, Aleardi M. Functional impairments in adults with self-reports of diagnosed ADHD: A controlled study of 1001 adults in the community. J Clin Psychiatry. 2006 Apr; 67(4):524-40. PMID: 16669717.
    Citations: 96     Fields:    Translation:Humans
  149. Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, Faraone SV, Greenhill LL, Howes MJ, Secnik K, Spencer T, Ustun TB, Walters EE, Zaslavsky AM. The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. Am J Psychiatry. 2006 Apr; 163(4):716-23. PMID: 16585449.
    Citations: 565     Fields:    Translation:Humans
  150. Spencer TJ, Abikoff HB, Connor DF, Biederman J, Pliszka SR, Boellner S, Read SC, Pratt R. Efficacy and safety of mixed amphetamine salts extended release (adderall XR) in the management of oppositional defiant disorder with or without comorbid attention-deficit/hyperactivity disorder in school-aged children and adolescents: A 4-week, multicenter, randomized, double-blind, parallel-group, placebo-controlled, forced-dose-escalation study. Clin Ther. 2006 Mar; 28(3):402-18. PMID: 16750455.
    Citations: 15     Fields:    Translation:Humans
  151. Spencer TJ, Faraone SV, Michelson D, Adler LA, Reimherr FW, Glatt SJ, Biederman J. Atomoxetine and adult attention-deficit/hyperactivity disorder: the effects of comorbidity. J Clin Psychiatry. 2006 Mar; 67(3):415-20. PMID: 16649828.
    Citations: 11     Fields:    Translation:Humans
  152. Spencer TJ, Biederman J, Ciccone PE, Madras BK, Dougherty DD, Bonab AA, Livni E, Parasrampuria DA, Fischman AJ. PET study examining pharmacokinetics, detection and likeability, and dopamine transporter receptor occupancy of short- and long-acting oral methylphenidate. Am J Psychiatry. 2006 Mar; 163(3):387-95. PMID: 16513858.
    Citations: 58     Fields:    Translation:HumansCellsPHPublic Health
  153. Biederman J, Wigal SB, Spencer TJ, McGough JJ, Mays DA. A post hoc subgroup analysis of an 18-day randomized controlled trial comparing the tolerability and efficacy of mixed amphetamine salts extended release and atomoxetine in school-age girls with attention-deficit/hyperactivity disorder. Clin Ther. 2006 Feb; 28(2):280-93. PMID: 16678649.
    Citations: 6     Fields:    Translation:Humans
  154. Biederman J, Monuteaux MC, Mick E, Spencer T, Wilens TE, Silva JM, Snyder LE, Faraone SV. Young adult outcome of attention deficit hyperactivity disorder: a controlled 10-year follow-up study. Psychol Med. 2006 Feb; 36(2):167-79. PMID: 16420713.
    Citations: 169     Fields:    Translation:Humans
  155. Doyle RL, Frazier J, Spencer TJ, Geller D, Biederman J, Wilens T. Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series. J Atten Disord. 2006 Feb; 9(3):543-9. PMID: 16481671.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  156. Spencer TJ, Wilens TE, Biederman J, Weisler RH, Read SC, Pratt R. Efficacy and safety of mixed amphetamine salts extended release (Adderall XR) in the management of attention-deficit/hyperactivity disorder in adolescent patients: a 4-week, randomized, double-blind, placebo-controlled, parallel-group study. Clin Ther. 2006 Feb; 28(2):266-79. PMID: 16678648.
    Citations: 24     Fields:    Translation:Humans
  157. Spencer TJ. ADHD and comorbidity in childhood. J Clin Psychiatry. 2006; 67 Suppl 8:27-31. PMID: 16961427.
    Citations: 44     Fields:    Translation:Humans
  158. Biederman J, Arnsten AF, Faraone SV, Doyle AE, Spencer TJ, Wilens TE, Weiss MD, Safren SA, Culpepper L. New developments in the treatment of ADHD. J Clin Psychiatry. 2006 Jan; 67(1):148-59. PMID: 16426101.
    Citations: 11     Fields:    Translation:Humans
  159. Biederman J, Mick E, Surman C, Doyle R, Hammerness P, Harpold T, Dunkel S, Dougherty M, Aleardi M, Spencer T. A randomized, placebo-controlled trial of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2006 May 01; 59(9):829-35. PMID: 16373066.
    Citations: 62     Fields:    Translation:HumansCTClinical Trials
  160. Wilens TE, Waxmonsky J, Scott M, Swezey A, Kwon A, Spencer TJ, Biederman J. An open trial of adjunctive donepezil in attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2005 Dec; 15(6):947-55. PMID: 16379515.
    Citations: 6     Fields:    Translation:Humans
  161. Weisler RH, Biederman J, Spencer TJ, Wilens TE. Long-term cardiovascular effects of mixed amphetamine salts extended release in adults with ADHD. CNS Spectr. 2005 Dec; 10(12 Suppl 20):35-43. PMID: 16344839.
    Citations: 14     Fields:    Translation:Humans
  162. Biederman J, Spencer TJ, Wilens TE, Weisler RH, Read SC, Tulloch SJ. Long-term safety and effectiveness of mixed amphetamine salts extended release in adults with ADHD. CNS Spectr. 2005 Dec; 10(12 Suppl 20):16-25. PMID: 16344837.
    Citations: 13     Fields:    Translation:Humans
  163. Faraone SV, Biederman J, Spencer T, Michelson D, Adler L, Reimherr F, Glatt SJ. Efficacy of atomoxetine in adult attention-deficit/hyperactivity disorder: a drug-placebo response curve analysis. Behav Brain Funct. 2005 Oct 03; 1:16. PMID: 16202140.
    Citations: 17     Fields:    
  164. Connor DF, Spencer TJ. Short-term cardiovascular effects of mixed amphetamine salts extended release in children and adolescents with oppositional defiant disorder. CNS Spectr. 2005 Oct; 10(10 Suppl 15):31-8. PMID: 17151574.
    Citations:    
  165. Wilens TE, Spencer TJ, Biederman J. Short- and long-term cardiovascular effects of mixed amphetamine salts extended-release in adolescents with ADHD. CNS Spectr. 2005 Oct; 10(10 Suppl 15):22-30. PMID: 17151573.
    Citations:    
  166. Spencer TJ, Biederman J, Wilens TE. Efficacy and tolerability of long-term, open-label, mixed amphetamine salts extended release in adolescents with ADHD. CNS Spectr. 2005 Oct; 10(10 Suppl 15):14-21. PMID: 17151572.
    Citations:    
  167. Wilens T, McBurnett K, Stein M, Lerner M, Spencer T, Wolraich M. ADHD treatment with once-daily OROS methylphenidate: final results from a long-term open-label study. J Am Acad Child Adolesc Psychiatry. 2005 Oct; 44(10):1015-23. PMID: 16175106.
    Citations: 20