Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Gregory L. Verdine, Ph.D.


Development of a Novel Chemical Cross-Link for Peptide Stabilization
Summer, 06/01/09 - 09/01/09

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA100742 (VERDINE, GREGORY LAWRENCE) Apr 1, 2003 - Nov 30, 2013
    Structure and Mechanism in DNA Excision Repair
    Role: Principal Investigator
  2. P41RR015301 (EALICK, STEVEN E) Jun 15, 2001 - Mar 31, 2013
    An Undulator Resource for Structural Biology
    Role: Co-Principal Investigator
  3. P41RR012408 (SWEET, ROBERT M) Sep 30, 1998 - Jun 30, 2013
    Macromolecular Crystallography at the National Synchrotron Light Source
    Role: Co-Principal Investigator
  4. R01GM051330 (VERDINE, GREGORY L) May 1, 1996 - Apr 30, 2000
    Role: Principal Investigator
  5. R55GM051330 (VERDINE, GREGORY L) Sep 15, 1994 - Apr 30, 1996
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang X, Dong L, Cheng J, Verdine GL, Lin A, Chu Q. Targeted ß-catenin ubiquitination and degradation by multifunctional stapled peptides. J Pept Sci. 2021 Dec 22; e3389. PMID: 34937123.
    Citations:    Fields:    
  2. Shigdel UK, Ovchinnikov V, Lee SJ, Shih JA, Karplus M, Nam K, Verdine GL. The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun. 2020 09 07; 11(1):4437. PMID: 32895378.
    Citations: 6     Fields:    Translation:Cells
  3. Chatterjee N, D'Souza S, Shabab M, Harris CA, Hilinski GJ, Verdine GL, Walker GC. A stapled POL ? peptide targets REV1 to inhibit mutagenic translesion synthesis. Environ Mol Mutagen. 2020 10; 61(8):830-836. PMID: 32573829.
    Citations: 3     Fields:    
  4. Shigdel UK, Lee SJ, Sowa ME, Bowman BR, Robison K, Zhou M, Pua KH, Stiles DT, Blodgett JAV, Udwary DW, Rajczewski AT, Mann AS, Mostafavi S, Hardy T, Arya S, Weng Z, Stewart M, Kenyon K, Morgenstern JP, Pan E, Gray DC, Pollock RM, Fry AM, Klausner RD, Townson SA, Verdine GL. Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):17195-17203. PMID: 32606248.
    Citations: 11     Fields:    Translation:HumansCells
  5. Lee SJ, Sung RJ, Verdine GL. Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System. Research (Wash D C). 2019; 2019:5641746. PMID: 31549070.
    Citations: 4     
  6. Xu L, Li Y, Biggins JB, Bowman BR, Verdine GL, Gloer JB, Alspaugh JA, Bills GF. Identification of cyclosporin C from Amphichorda felina using a Cryptococcus neoformans differential temperature sensitivity assay. Appl Microbiol Biotechnol. 2018 Mar; 102(5):2337-2350. PMID: 29396588.
    Citations: 6     Fields:    Translation:Animals
  7. McGee JH, Shim SY, Lee SJ, Swanson PK, Jiang SY, Durney MA, Verdine GL. Exceptionally high-affinity Ras binders that remodel its effector domain. J Biol Chem. 2018 03 02; 293(9):3265-3280. PMID: 29282294.
    Citations: 9     Fields:    Translation:Cells
  8. Mitra S, Montgomery JE, Kolar MJ, Li G, Jeong KJ, Peng B, Verdine GL, Mills GB, Moellering RE. Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer. Nat Commun. 2017 09 22; 8(1):660. PMID: 28939823.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  9. Iwamoto N, Butler DCD, Svrzikapa N, Mohapatra S, Zlatev I, Sah DWY, Standley SM, Lu G, Apponi LH, Frank-Kamenetsky M, Zhang JJ, Vargeese C, Verdine GL. Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides. Nat Biotechnol. 2017 Sep; 35(9):845-851. PMID: 28829437.
    Citations: 67     Fields:    Translation:HumansAnimals
  10. Kauke MJ, Traxlmayr MW, Parker JA, Kiefer JD, Knihtila R, McGee J, Verdine G, Mattos C, Wittrup KD. An engineered protein antagonist of K-Ras/B-Raf interaction. Sci Rep. 2017 07 19; 7(1):5831. PMID: 28724936.
    Citations: 24     Fields:    Translation:HumansCells
  11. Levinson AM, McGee JH, Roberts AG, Creech GS, Wang T, Peterson MT, Hendrickson RC, Verdine GL, Danishefsky SJ. Total Chemical Synthesis and Folding of All-l and All-d Variants of Oncogenic KRas(G12V). J Am Chem Soc. 2017 06 07; 139(22):7632-7639. PMID: 28448128.
    Citations: 6     Fields:    Translation:HumansCells
  12. Wang L, Chakravarthy S, Verdine GL. Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase. J Biol Chem. 2017 03 24; 292(12):5007-5017. PMID: 28130451.
    Citations: 12     Fields:    Translation:Cells
  13. Pua KH, Stiles DT, Sowa ME, Verdine GL. IMPDH2 Is an Intracellular Target of the Cyclophilin A and Sanglifehrin A Complex. Cell Rep. 2017 01 10; 18(2):432-442. PMID: 28076787.
    Citations: 11     Fields:    Translation:HumansCells
  14. Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nat Biotechnol. 2016 07; 34(7):738-45. PMID: 27272386.
    Citations: 80     Fields:    Translation:AnimalsCells
  15. Amit I, Baker D, Barker R, Berger B, Bertozzi C, Bhatia S, Biffi A, Demichelis F, Doudna J, Dowdy SF, Endy D, Helmstaedter M, Junca H, June C, Kamb S, Khvorova A, Kim DH, Kim JS, Krishnan Y, Lakadamyali M, Lappalainen T, Lewin S, Liao J, Loman N, Lundberg E, Lynd L, Martin C, Mellman I, Miyawaki A, Mummery C, Nelson K, Paz J, Peralta-Yahya P, Picotti P, Polyak K, Prather K, Qin J, Quake S, Regev A, Rogers JA, Shetty R, Sommer M, Stevens M, Stolovitzky G, Takahashi M, Tang F, Teichmann S, Torres-Padilla ME, Tripathi L, Vemula P, Verdine G, Vollmer F, Wang J, Ying JY, Zhang F, Zhang T. Voices of biotech. Nat Biotechnol. 2016 Mar; 34(3):270-5. PMID: 26963549.
    Citations: 2     Fields:    Translation:Humans
  16. Hilinski GJ, Kim YW, Hong J, Kutchukian PS, Crenshaw CM, Berkovitch SS, Chang A, Ham S, Verdine GL. Correction to "Stitched a-Helical Peptides via Bis Ring-Closing Metathesis". J Am Chem Soc. 2015 Jul 15; 137(27):8858. PMID: 26134449.
    Citations:    Fields:    
  17. Wang L, Lee SJ, Verdine GL. Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase. J Biol Chem. 2015 Jul 10; 290(28):17096-105. PMID: 25995449.
    Citations: 9     Fields:    Translation:Cells
  18. Hilinski GJ, Kim YW, Hong J, Kutchukian PS, Crenshaw CM, Berkovitch SS, Chang A, Ham S, Verdine GL. Stitched a-helical peptides via bis ring-closing metathesis. J Am Chem Soc. 2014 Sep 03; 136(35):12314-22. PMID: 25105213.
    Citations: 26     Fields:    Translation:HumansCells
  19. Shim SY, Kim YW, Verdine GL. A new i, i + 3 peptide stapling system for a-helix stabilization. Chem Biol Drug Des. 2013 Dec; 82(6):635-42. PMID: 24267668.
    Citations: 7     Fields:    Translation:Cells
  20. Sung RJ, Zhang M, Qi Y, Verdine GL. Structural and biochemical analysis of DNA helix invasion by the bacterial 8-oxoguanine DNA glycosylase MutM. J Biol Chem. 2013 Apr 05; 288(14):10012-10023. PMID: 23404556.
    Citations: 14     Fields:    Translation:Cells
  21. Grossmann TN, Yeh JT, Bowman BR, Chu Q, Moellering RE, Verdine GL. Inhibition of oncogenic Wnt signaling through direct targeting of ß-catenin. Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44):17942-7. PMID: 23071338.
    Citations: 85     Fields:    Translation:HumansCells
  22. Didovyk A, Verdine GL. Structural origins of DNA target selection and nucleobase extrusion by a DNA cytosine methyltransferase. J Biol Chem. 2012 Nov 23; 287(48):40099-105. PMID: 23012373.
    Citations:    Fields:    Translation:Cells
  23. Crenshaw CM, Nam K, Oo K, Kutchukian PS, Bowman BR, Karplus M, Verdine GL. Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J Biol Chem. 2012 Jul 20; 287(30):24916-28. PMID: 22511791.
    Citations: 23     Fields:    Translation:HumansCells
  24. Sung RJ, Zhang M, Qi Y, Verdine GL. Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J Biol Chem. 2012 May 25; 287(22):18044-54. PMID: 22465958.
    Citations: 10     Fields:    Translation:Cells
  25. Gude L, Berkovitch SS, Santos WL, Kutchukian PS, Pawloski AR, Kuimelis R, McGall G, Verdine GL. Mapping targetable sites on human telomerase RNA pseudoknot/template domain using 2'-OMe RNA-interacting polynucleotide (RIPtide) microarrays. J Biol Chem. 2012 May 25; 287(22):18843-53. PMID: 22451672.
    Citations: 8     Fields:    Translation:HumansCells
  26. Qi Y, Nam K, Spong MC, Banerjee A, Sung RJ, Zhang M, Karplus M, Verdine GL. Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1086-91. PMID: 22219368.
    Citations: 18     Fields:    Translation:Cells
  27. Wittrup KD, Verdine GL. Protein engineering for therapeutics, Part A. Preface. Methods Enzymol. 2012; 502:xiii-xiv. PMID: 22208991.
    Citations: 2     Fields:    Translation:Humans
  28. Wittrup KD, Verdine GL. Protein engineering for therapeutics, part B. Preface. Methods Enzymol. 2012; 503:xiii-xiv. PMID: 22230575.
    Citations: 1     Fields:    Translation:Humans
  29. Verdine GL, Hilinski GJ. Stapled peptides for intracellular drug targets. Methods Enzymol. 2012; 503:3-33. PMID: 22230563.
    Citations: 148     Fields:    Translation:HumansAnimalsCells
  30. Baek S, Kutchukian PS, Verdine GL, Huber R, Holak TA, Lee KW, Popowicz GM. Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc. 2012 Jan 11; 134(1):103-6. PMID: 22148351.
    Citations: 62     Fields:    Translation:HumansCells
  31. Kim YW, Grossmann TN, Verdine GL. Synthesis of all-hydrocarbon stapled a-helical peptides by ring-closing olefin metathesis. Nat Protoc. 2011 Jun; 6(6):761-71. PMID: 21637196.
    Citations: 100     Fields:    Translation:Cells
  32. Bowman BR, Lee S, Wang S, Verdine GL. Structure of Escherichia coli AlkA in complex with undamaged DNA. J Biol Chem. 2010 Nov 12; 285(46):35783-91. PMID: 20843803.
    Citations: 14     Fields:    Translation:Cells
  33. Kim YW, Kutchukian PS, Verdine GL. Introduction of all-hydrocarbon i,i+3 staples into alpha-helices via ring-closing olefin metathesis. Org Lett. 2010 Jul 02; 12(13):3046-9. PMID: 20527740.
    Citations: 25     Fields:    Translation:Cells
  34. Nam K, Verdine GL, Karplus M. Analysis of an anomalous mutant of MutM DNA glycosylase leads to new insights into the catalytic mechanism. J Am Chem Soc. 2009 Dec 30; 131(51):18208-9. PMID: 19961158.
    Citations: 9     Fields:    Translation:Cells
  35. Qi Y, Spong MC, Nam K, Banerjee A, Jiralerspong S, Karplus M, Verdine GL. Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature. 2009 Dec 10; 462(7274):762-6. PMID: 20010681.
    Citations: 67     Fields:    Translation:Cells
  36. Moellering RE, Cornejo M, Davis TN, Del Bianco C, Aster JC, Blacklow SC, Kung AL, Gilliland DG, Verdine GL, Bradner JE. Direct inhibition of the NOTCH transcription factor complex. Nature. 2009 Nov 12; 462(7270):182-8. PMID: 19907488.
    Citations: 331     Fields:    Translation:HumansAnimalsCells
  37. Blainey PC, Luo G, Kou SC, Mangel WF, Verdine GL, Bagchi B, Xie XS. Nonspecifically bound proteins spin while diffusing along DNA. Nat Struct Mol Biol. 2009 Dec; 16(12):1224-9. PMID: 19898474.
    Citations: 158     Fields:    Translation:Cells
  38. Qi Y, Spong MC, Nam K, Karplus M, Verdine GL. Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J Biol Chem. 2010 Jan 08; 285(2):1468-78. PMID: 19889642.
    Citations: 25     Fields:    Translation:Cells
  39. Lee S, Verdine GL. Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18497-502. PMID: 19841264.
    Citations: 43     Fields:    Translation:Cells
  40. Kutchukian PS, Yang JS, Verdine GL, Shakhnovich EI. All-atom model for stabilization of alpha-helical structure in peptides by hydrocarbon staples. J Am Chem Soc. 2009 Apr 08; 131(13):4622-7. PMID: 19334772.
    Citations: 30     Fields:    Translation:Cells
  41. Pakotiprapha D, Liu Y, Verdine GL, Jeruzalmi D. A structural model for the damage-sensing complex in bacterial nucleotide excision repair. J Biol Chem. 2009 May 08; 284(19):12837-44. PMID: 19287003.
    Citations: 27     Fields:    Translation:Cells
  42. Kim YW, Verdine GL. Stereochemical effects of all-hydrocarbon tethers in i,i+4 stapled peptides. Bioorg Med Chem Lett. 2009 May 01; 19(9):2533-6. PMID: 19332370.
    Citations: 16     Fields:    Translation:HumansCells
  43. Lee S, Bowman BR, Ueno Y, Wang S, Verdine GL. Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc. 2008 Sep 03; 130(35):11570-1. PMID: 18686953.
    Citations: 28     Fields:    Translation:Cells
  44. Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM. The human cytomegalovirus UL44 C clamp wraps around DNA. Structure. 2008 Aug 06; 16(8):1214-25. PMID: 18682223.
    Citations: 18     Fields:    Translation:HumansCells
  45. Bowman BR, Lee S, Wang S, Verdine GL. Structure of the E. coli DNA glycosylase AlkA bound to the ends of duplex DNA: a system for the structure determination of lesion-containing DNA. Structure. 2008 Aug 06; 16(8):1166-74. PMID: 18682218.
    Citations: 22     Fields:    Translation:Cells
  46. Lee S, Radom CT, Verdine GL. Trapping and structural elucidation of a very advanced intermediate in the lesion-extrusion pathway of hOGG1. J Am Chem Soc. 2008 Jun 25; 130(25):7784-5. PMID: 18507380.
    Citations: 12     Fields:    Translation:HumansCells
  47. Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM. The positively charged surface of herpes simplex virus UL42 mediates DNA binding. J Biol Chem. 2008 Mar 07; 283(10):6154-61. PMID: 18178550.
    Citations: 18     Fields:    Translation:Cells
  48. Pakotiprapha D, Inuzuka Y, Bowman BR, Moolenaar GF, Goosen N, Jeruzalmi D, Verdine GL. Crystal structure of Bacillus stearothermophilus UvrA provides insight into ATP-modulated dimerization, UvrB interaction, and DNA binding. Mol Cell. 2008 Jan 18; 29(1):122-33. PMID: 18158267.
    Citations: 45     Fields:    Translation:Cells
  49. Zhao Z, McKee CJ, Kessl JJ, Santos WL, Daigle JE, Engelman A, Verdine G, Kvaratskhelia M. Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding. J Biol Chem. 2008 Feb 29; 283(9):5632-41. PMID: 18093980.
    Citations: 39     Fields:    Translation:HumansCells
  50. Verdine GL, Walensky LD. The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members. Clin Cancer Res. 2007 Dec 15; 13(24):7264-70. PMID: 18094406.
    Citations: 144     Fields:    Translation:HumansAnimalsCells
  51. Lee S, Uttamapinant C, Verdine GL. A concise synthesis of 4'-fluoro nucleosides. Org Lett. 2007 Nov 22; 9(24):5007-9. PMID: 17975917.
    Citations: 2     Fields:    Translation:Cells
  52. Bernal F, Tyler AF, Korsmeyer SJ, Walensky LD, Verdine GL. Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide. J Am Chem Soc. 2007 Mar 07; 129(9):2456-7. PMID: 17284038.
    Citations: 170     Fields:    Translation:HumansCells
  53. Radom CT, Banerjee A, Verdine GL. Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J Biol Chem. 2007 Mar 23; 282(12):9182-94. PMID: 17114185.
    Citations: 34     Fields:    Translation:HumansCells
  54. Walensky LD, Pitter K, Morash J, Oh KJ, Barbuto S, Fisher J, Smith E, Verdine GL, Korsmeyer SJ. A stapled BID BH3 helix directly binds and activates BAX. Mol Cell. 2006 Oct 20; 24(2):199-210. PMID: 17052454.
    Citations: 171     Fields:    Translation:HumansCells
  55. Banerjee A, Verdine GL. A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15020-5. PMID: 17015827.
    Citations: 28     Fields:    Translation:HumansCells
  56. Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol. 2006 Aug; 13(8):713-9. PMID: 16878130.
    Citations: 391     Fields:    Translation:HumansCells
  57. Ruthenburg AJ, Wang W, Graybosch DM, Li H, Allis CD, Patel DJ, Verdine GL. Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol. 2006 Aug; 13(8):704-12. PMID: 16829959.
    Citations: 108     Fields:    Translation:HumansCells
  58. Blainey PC, van Oijen AM, Banerjee A, Verdine GL, Xie XS. A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5752-7. PMID: 16585517.
    Citations: 240     Fields:    Translation:HumansCells
  59. Banerjee A, Santos WL, Verdine GL. Structure of a DNA glycosylase searching for lesions. Science. 2006 Feb 24; 311(5764):1153-7. PMID: 16497933.
    Citations: 102     Fields:    Translation:Cells
  60. Losey HC, Ruthenburg AJ, Verdine GL. Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA. Nat Struct Mol Biol. 2006 Feb; 13(2):153-9. PMID: 16415880.
    Citations: 84     Fields:    Translation:Cells
  61. Verdine GL. Drugging the "undruggable". Harvey Lect. 2006-2007; 102:1-15. PMID: 20166561.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  62. Johnson AA, Santos W, Pais GC, Marchand C, Amin R, Burke TR, Verdine G, Pommier Y. Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop. J Biol Chem. 2006 Jan 06; 281(1):461-7. PMID: 16257967.
    Citations: 34     Fields:    Translation:Cells
  63. He C, Hus JC, Sun LJ, Zhou P, Norman DP, Dötsch V, Wei H, Gross JD, Lane WS, Wagner G, Verdine GL. A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada. Mol Cell. 2005 Oct 07; 20(1):117-29. PMID: 16209950.
    Citations: 29     Fields:    Translation:Cells
  64. Plummer KA, Carothers JM, Yoshimura M, Szostak JW, Verdine GL. In vitro selection of RNA aptamers against a composite small molecule-protein surface. Nucleic Acids Res. 2005; 33(17):5602-10. PMID: 16199752.
    Citations: 2     Fields:    Translation:HumansCells
  65. Wei H, Ruthenburg AJ, Bechis SK, Verdine GL. Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase. J Biol Chem. 2005 Nov 04; 280(44):37041-7. PMID: 16100112.
    Citations: 54     Fields:    Translation:HumansCells
  66. Ruthenburg AJ, Graybosch DM, Huetsch JC, Verdine GL. A superhelical spiral in the Escherichia coli DNA gyrase A C-terminal domain imparts unidirectional supercoiling bias. J Biol Chem. 2005 Jul 15; 280(28):26177-84. PMID: 15897198.
    Citations: 49     Fields:    Translation:Cells
  67. Banerjee A, Yang W, Karplus M, Verdine GL. Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature. 2005 Mar 31; 434(7033):612-8. PMID: 15800616.
    Citations: 145     Fields:    Translation:HumansCells
  68. Chung SJ, Fromme JC, Verdine GL. Structure of human cytidine deaminase bound to a potent inhibitor. J Med Chem. 2005 Feb 10; 48(3):658-60. PMID: 15689149.
    Citations: 27     Fields:    Translation:HumansCells
  69. Chung SJ, Verdine GL. Structures of end products resulting from lesion processing by a DNA glycosylase/lyase. Chem Biol. 2004 Dec; 11(12):1643-9. PMID: 15610848.
    Citations: 9     Fields:    Translation:HumansCells
  70. Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL, Korsmeyer SJ. Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix. Science. 2004 Sep 03; 305(5689):1466-70. PMID: 15353804.
    Citations: 424     Fields:    Translation:HumansAnimalsCells
  71. Fromme JC, Banerjee A, Huang SJ, Verdine GL. Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature. 2004 Feb 12; 427(6975):652-6. PMID: 14961129.
    Citations: 135     Fields:    Translation:Cells
  72. Fromme JC, Banerjee A, Verdine GL. DNA glycosylase recognition and catalysis. Curr Opin Struct Biol. 2004 Feb; 14(1):43-9. PMID: 15102448.
    Citations: 74     Fields:    Translation:Cells
  73. Fromme JC, Verdine GL. Base excision repair. Adv Protein Chem. 2004; 69:1-41. PMID: 15588838.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  74. Fromme JC, Verdine GL. DNA lesion recognition by the bacterial repair enzyme MutM. J Biol Chem. 2003 Dec 19; 278(51):51543-8. PMID: 14525999.
    Citations: 74     Fields:    Translation:Cells
  75. Fromme JC, Verdine GL. Structure of a trapped endonuclease III-DNA covalent intermediate. EMBO J. 2003 Jul 01; 22(13):3461-71. PMID: 12840008.
    Citations: 85     Fields:    Translation:HumansCells
  76. Wibley JE, Waters TR, Haushalter K, Verdine GL, Pearl LH. Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1. Mol Cell. 2003 Jun; 11(6):1647-59. PMID: 12820976.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  77. Gierasch TM, Shi Z, Verdine GL. Extensively stereodiversified scaffolds for use in diversity-oriented library synthesis. Org Lett. 2003 Mar 06; 5(5):621-4. PMID: 12605474.
    Citations: 2     Fields:    
  78. Shi Z, Harrison BA, Verdine GL. Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols. Org Lett. 2003 Mar 06; 5(5):633-6. PMID: 12605477.
    Citations: 1     Fields:    Translation:AnimalsCells
  79. Fromme JC, Bruner SD, Yang W, Karplus M, Verdine GL. Product-assisted catalysis in base-excision DNA repair. Nat Struct Biol. 2003 Mar; 10(3):204-11. PMID: 12592398.
    Citations: 49     Fields:    Translation:Cells
  80. Harrison BA, Pasternak GW, Verdine GL. 2,6-Dimethyltyrosine analogues of a stereodiversified ligand library: highly potent, selective, non-peptidic mu opioid receptor agonists. J Med Chem. 2003 Feb 27; 46(5):677-80. PMID: 12593647.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  81. Norman DP, Chung SJ, Verdine GL. Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase. Biochemistry. 2003 Feb 18; 42(6):1564-72. PMID: 12578369.
    Citations: 32     Fields:    Translation:HumansCells
  82. He C, Wei H, Verdine GL. Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme. J Am Chem Soc. 2003 Feb 12; 125(6):1450-1. PMID: 12568584.
    Citations: 4     Fields:    Translation:Cells
  83. Verdine GL, Norman DP. Covalent trapping of protein-DNA complexes. Annu Rev Biochem. 2003; 72:337-66. PMID: 14527324.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  84. He C, Verdine GL. Trapping distinct structural states of a protein/DNA interaction through disulfide crosslinking. Chem Biol. 2002 Dec; 9(12):1297-303. PMID: 12498882.
    Citations: 13     Fields:    Translation:Cells
  85. Harrison BA, Gierasch TM, Neilan C, Pasternak GW, Verdine GL. High-affinity mu opioid receptor ligands discovered by the screening of an exhaustively stereodiversified library of 1,5-enediols. J Am Chem Soc. 2002 Nov 13; 124(45):13352-3. PMID: 12418865.
    Citations: 8     Fields:    
  86. Storek MJ, Suciu A, Verdine GL. 5-amino-2'-deoxyuridine, a novel thymidine analogue for high-resolution footprinting of protein-DNA complexes. Org Lett. 2002 Oct 31; 4(22):3867-9. PMID: 12599479.
    Citations: 3     Fields:    Translation:Cells
  87. Michielin O, Zoete V, Gierasch TM, Eckstein J, Napper A, Verdine G, Karplus M. Conformational analysis of a stereochemically complete set of cis-enediol peptide analogues. J Am Chem Soc. 2002 Sep 18; 124(37):11131-41. PMID: 12224961.
    Citations: 1     Fields:    Translation:HumansCells
  88. Wolfe JL, Kawate T, Sarracino DA, Zillmann M, Olson J, Stanton VP, Verdine GL. A genotyping strategy based on incorporation and cleavage of chemically modified nucleotides. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11073-8. PMID: 12169663.
    Citations: 3     Fields:    Translation:HumansCells
  89. Fromme JC, Verdine GL. Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. Nat Struct Biol. 2002 Jul; 9(7):544-52. PMID: 12055620.
    Citations: 66     Fields:    Translation:Cells
  90. Chen L, Haushalter KA, Lieber CM, Verdine GL. Direct visualization of a DNA glycosylase searching for damage. Chem Biol. 2002 Mar; 9(3):345-50. PMID: 11927259.
    Citations: 42     Fields:    Translation:HumansCells
  91. Storek MJ, Ernst A, Verdine GL. High-resolution footprinting of sequence-specific protein-DNA contacts. Nat Biotechnol. 2002 Feb; 20(2):183-6. PMID: 11821865.
    Citations: 4     Fields:    Translation:HumansCells
  92. Sun LJ, Yim CK, Verdine GL. Chemical communication across the zinc tetrathiolate cluster in Escherichia coli Ada, a metalloactivated DNA repair protein. Biochemistry. 2001 Sep 25; 40(38):11596-603. PMID: 11560510.
    Citations: 4     Fields:    Translation:Cells
  93. Nilsen H, Haushalter KA, Robins P, Barnes DE, Verdine GL, Lindahl T. Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase. EMBO J. 2001 Aug 01; 20(15):4278-86. PMID: 11483530.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  94. Harrison BA, Verdine GL. The synthesis of an exhaustively stereodiversified library of cis-1,5 enediols by silyl-tethered ring-closing metathesis. Org Lett. 2001 Jul 12; 3(14):2157-9. PMID: 11440568.
    Citations: 3     Fields:    Translation:Cells
  95. Lin Y, Dötsch V, Wintner T, Peariso K, Myers LC, Penner-Hahn JE, Verdine GL, Wagner G. Structural basis for the functional switch of the E. coli Ada protein. Biochemistry. 2001 Apr 10; 40(14):4261-71. PMID: 11284682.
    Citations: 5     Fields:    Translation:Cells
  96. Koide K, Finkelstein JM, Ball Z, Verdine GL. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24; 123(3):398-408. PMID: 11456541.
    Citations: 6     Fields:    Translation:HumansCells
  97. Norman DP, Bruner SD, Verdine GL. Coupling of substrate recognition and catalysis by a human base-excision DNA repair protein. J Am Chem Soc. 2001 Jan 17; 123(2):359-60. PMID: 11456534.
    Citations: 20     Fields:    Translation:HumansCells
  98. Nyanguile O, Verdine GL. Template-directed interference footprinting of protein-phosphate contacts in DNA. Org Lett. 2001 Jan 11; 3(1):71-4. PMID: 11429875.
    Citations:    Fields:    Translation:HumansCells
  99. Gierasch TM, Chytil M, Didiuk MT, Park JY, Urban JJ, Nolan SP, Verdine GL. A modular synthetic approach toward exhaustively stereodiversified ligand libraries. Org Lett. 2000 Dec 14; 2(25):3999-4002. PMID: 11112627.
    Citations: 3     Fields:    Translation:Cells
  100. Sekino Y, Bruner SD, Verdine GL. Selective inhibition of herpes simplex virus type-1 uracil-DNA glycosylase by designed substrate analogs. J Biol Chem. 2000 Nov 24; 275(47):36506-8. PMID: 11084051.
    Citations: 5     Fields:    Translation:HumansCells
  101. Dow LK, Jones DN, Wolfe SA, Verdine GL, Churchill ME. Structural studies of the high mobility group globular domain and basic tail of HMG-D bound to disulfide cross-linked DNA. Biochemistry. 2000 Aug 15; 39(32):9725-36. PMID: 10933789.
    Citations: 12     Fields:    Translation:AnimalsCells
  102. Park S, Uesugi M, Verdine GL. A second calcineurin binding site on the NFAT regulatory domain. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7130-5. PMID: 10860980.
    Citations: 37     Fields:    Translation:HumansCells
  103. Huang H, Harrison SC, Verdine GL. Trapping of a catalytic HIV reverse transcriptase*template:primer complex through a disulfide bond. Chem Biol. 2000 May; 7(5):355-64. PMID: 10801473.
    Citations: 24     Fields:    Translation:Cells
  104. Bruner SD, Norman DP, Verdine GL. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature. 2000 Feb 24; 403(6772):859-66. PMID: 10706276.
    Citations: 297     Fields:    Translation:HumansCells
  105. Bruner SD, Norman DP, Fromme JC, Verdine GL. Structural and mechanistic studies on repair of 8-oxoguanine in mammalian cells. Cold Spring Harb Symp Quant Biol. 2000; 65:103-11. PMID: 12760025.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  106. Uesugi M, Verdine GL. The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14801-6. PMID: 10611293.
    Citations: 44     Fields:    Translation:HumansCells
  107. Barrett TE, Schärer OD, Savva R, Brown T, Jiricny J, Verdine GL, Pearl LH. Crystal structure of a thwarted mismatch glycosylase DNA repair complex. EMBO J. 1999 Dec 01; 18(23):6599-609. PMID: 10581234.
    Citations: 50     Fields:    Translation:Cells
  108. van Aalten DM, Erlanson DA, Verdine GL, Joshua-Tor L. A structural snapshot of base-pair opening in DNA. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):11809-14. PMID: 10518532.
    Citations: 6     Fields:    Translation:Cells
  109. Zhang XM, Verdine GL. A small region in HMG I(Y) is critical for cooperation with NF-kappaB on DNA. J Biol Chem. 1999 Jul 16; 274(29):20235-43. PMID: 10400641.
    Citations: 9     Fields:    Translation:AnimalsCells
  110. Haushalter KA, Todd Stukenberg MW, Kirschner MW, Verdine GL. Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr Biol. 1999 Feb 25; 9(4):174-85. PMID: 10074426.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  111. Cedar H, Verdine GL. Gene expression. The amazing demethylase. Nature. 1999 Feb 18; 397(6720):568-9. PMID: 10050847.
    Citations: 8     Fields:    Translation:Cells
  112. Huang H, Chopra R, Verdine GL, Harrison SC. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science. 1998 Nov 27; 282(5394):1669-75. PMID: 9831551.
    Citations: 525     Fields:    Translation:HumansCells
  113. Chytil M, Peterson BR, Erlanson DA, Verdine GL. The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency. Proc Natl Acad Sci U S A. 1998 Nov 24; 95(24):14076-81. PMID: 9826656.
    Citations: 11     Fields:    Translation:AnimalsCells
  114. Lau AY, Schärer OD, Samson L, Verdine GL, Ellenberger T. Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell. 1998 Oct 16; 95(2):249-58. PMID: 9790531.
    Citations: 93     Fields:    Translation:HumansCells
  115. Schärer OD, Nash HM, Jiricny J, Laval J, Verdine GL. Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases. J Biol Chem. 1998 Apr 10; 273(15):8592-7. PMID: 9535832.
    Citations: 33     Fields:    Translation:Cells
  116. Bruner SD, Nash HM, Lane WS, Verdine GL. Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway. Curr Biol. 1998 Mar 26; 8(7):393-403. PMID: 9545197.
    Citations: 20     Fields:    Translation:AnimalsCells
  117. Zhou P, Sun LJ, Dötsch V, Wagner G, Verdine GL. Solution structure of the core NFATC1/DNA complex. Cell. 1998 Mar 06; 92(5):687-96. PMID: 9506523.
    Citations: 20     Fields:    Translation:HumansCells
  118. Nyanguile O, Uesugi M, Austin DJ, Verdine GL. A nonnatural transcriptional coactivator. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):13402-6. PMID: 9391036.
    Citations: 13     Fields:    Translation:HumansCells
  119. Schärer OD, Deng L, Verdine GL. Chemical approaches toward understanding base excision DNA repair. Curr Opin Chem Biol. 1997 Dec; 1(4):526-31. PMID: 9667887.
    Citations: 2     Fields:    Translation:Cells
  120. Cramer P, Larson CJ, Verdine GL, Müller CW. Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution. EMBO J. 1997 Dec 01; 16(23):7078-90. PMID: 9384586.
    Citations: 33     Fields:    Translation:HumansCells
  121. Nash HM, Lu R, Lane WS, Verdine GL. The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution. Chem Biol. 1997 Sep; 4(9):693-702. PMID: 9331411.
    Citations: 47     Fields:    Translation:HumansCells
  122. Uesugi M, Nyanguile O, Lu H, Levine AJ, Verdine GL. Induced alpha helix in the VP16 activation domain upon binding to a human TAF. Science. 1997 Aug 29; 277(5330):1310-3. PMID: 9271577.
    Citations: 112     Fields:    Translation:HumansCells
  123. Yoder JA, Soman NS, Verdine GL, Bestor TH. DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe. J Mol Biol. 1997 Jul 18; 270(3):385-95. PMID: 9237905.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  124. Lu R, Nash HM, Verdine GL. A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer. Curr Biol. 1997 Jun 01; 7(6):397-407. PMID: 9197244.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  125. Sun LJ, Peterson BR, Verdine GL. Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1. Proc Natl Acad Sci U S A. 1997 May 13; 94(10):4919-24. PMID: 9144165.
    Citations: 12     Fields:    Translation:AnimalsCells
  126. Schärer OD, Kawate T, Gallinari P, Jiricny J, Verdine GL. Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors. Proc Natl Acad Sci U S A. 1997 May 13; 94(10):4878-83. PMID: 9144158.
    Citations: 34     Fields:    Translation:HumansCells
  127. Verdine GL, Bruner SD. How do DNA repair proteins locate damaged bases in the genome? Chem Biol. 1997 May; 4(5):329-34. PMID: 9195879.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  128. Wolfe SA, Zhou P, Dötsch V, Chen L, You A, Ho SN, Crabtree GR, Wagner G, Verdine GL. Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. Nature. 1997 Jan 09; 385(6612):172-6. PMID: 8990122.
    Citations: 24     Fields:    Translation:HumansCells
  129. McCullough AK, Schärer O, Verdine GL, Lloyd RS. Structural determinants for specific recognition by T4 endonuclease V. J Biol Chem. 1996 Dec 13; 271(50):32147-52. PMID: 8943268.
    Citations: 7     Fields:    Translation:Cells
  130. Erlanson DA, Chytil M, Verdine GL. The leucine zipper domain controls the orientation of AP-1 in the NFAT.AP-1.DNA complex. Chem Biol. 1996 Dec; 3(12):981-91. PMID: 9000009.
    Citations: 33     Fields:    Translation:Cells
  131. Peterson BR, Sun LJ, Verdine GL. A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1. Proc Natl Acad Sci U S A. 1996 Nov 26; 93(24):13671-6. PMID: 8942992.
    Citations: 15     Fields:    Translation:AnimalsCells
  132. Verdine GL. The combinatorial chemistry of nature. Nature. 1996 Nov 07; 384(6604 Suppl):11-3. PMID: 8895593.
    Citations: 17     Fields:    
  133. Min C, Verdine GL. Immobilized metal affinity chromatography of DNA. Nucleic Acids Res. 1996 Oct 01; 24(19):3806-10. PMID: 8871562.
    Citations: 1     Fields:    Translation:Cells
  134. Zhang X, Verdine GL. Mammalian DNA cytosine-5 methyltransferase interacts with p23 protein. FEBS Lett. 1996 Aug 26; 392(2):179-83. PMID: 8772199.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  135. Nash HM, Bruner SD, Schärer OD, Kawate T, Addona TA, Spooner E, Lane WS, Verdine GL. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Curr Biol. 1996 Aug 01; 6(8):968-80. PMID: 8805338.
    Citations: 132     Fields:    Translation:AnimalsCells
  136. Labahn J, Schärer OD, Long A, Ezaz-Nikpay K, Verdine GL, Ellenberger TE. Structural basis for the excision repair of alkylation-damaged DNA. Cell. 1996 Jul 26; 86(2):321-9. PMID: 8706136.
    Citations: 77     Fields:    Translation:Cells
  137. Habazettl J, Myers LC, Yuan F, Verdine GL, Wagner G. Backbone dynamics, amide hydrogen exchange, and resonance assignments of the DNA methylphosphotriester repair domain of Escherichia coli Ada using NMR. Biochemistry. 1996 Jul 23; 35(29):9335-48. PMID: 8755711.
    Citations: 8     Fields:    Translation:Cells
  138. Dyer MA, Naidoo R, Hayes RJ, Larson CJ, Verdine GL, Baron MH. A DNA-bending protein interacts with an essential upstream regulatory element of the human embryonic beta-like globin gene. Mol Cell Biol. 1996 Mar; 16(3):829-38. PMID: 8622684.
    Citations: 6     Fields:    Translation:HumansCells
  139. Chytil M, Verdine GL. The Rel family of eukaryotic transcription factors. Curr Opin Struct Biol. 1996 Feb; 6(1):91-100. PMID: 8696978.
    Citations: 11     Fields:    Translation:AnimalsCells
  140. Allerson CR, Verdine GL. Synthesis and biochemical evaluation of RNA containing an intrahelical disulfide crosslink. Chem Biol. 1995 Oct; 2(10):667-75. PMID: 9383473.
    Citations: 10     Fields:    Translation:Cells
  141. Chen L, Oakley MG, Glover JN, Jain J, Dervan PB, Hogan PG, Rao A, Verdine GL. Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Curr Biol. 1995 Aug 01; 5(8):882-9. PMID: 7583146.
    Citations: 21     Fields:    Translation:Cells
  142. Reinisch KM, Chen L, Verdine GL, Lipscomb WN. The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing. Cell. 1995 Jul 14; 82(1):143-53. PMID: 7606780.
    Citations: 113     Fields:    Translation:Cells
  143. Stanojevic D, Verdine GL. Deconstruction of GCN4/GCRE into a monomeric peptide-DNA complex. Nat Struct Biol. 1995 Jun; 2(6):450-7. PMID: 7664107.
    Citations: 8     Fields:    Translation:Cells
  144. Wolfe SA, Ferentz AE, Grantcharova V, Churchill ME, Verdine GL. Modifying the helical structure of DNA by design: recruitment of an architecture-specific protein to an enforced DNA bend. Chem Biol. 1995 Apr; 2(4):213-21. PMID: 9383423.
    Citations: 10     Fields:    Translation:Cells
  145. Myers LC, Jackow F, Verdine GL. Metal dependence of transcriptional switching in Escherichia coli Ada. J Biol Chem. 1995 Mar 24; 270(12):6664-70. PMID: 7896807.
    Citations: 11     Fields:    Translation:Cells
  146. Müller CW, Rey FA, Sodeoka M, Verdine GL, Harrison SC. Structure of the NF-kappa B p50 homodimer bound to DNA. Nature. 1995 Jan 26; 373(6512):311-7. PMID: 7830764.
    Citations: 133     Fields:    Translation:HumansCells
  147. MacMillan AM, Query CC, Allerson CR, Chen S, Verdine GL, Sharp PA. Dynamic association of proteins with the pre-mRNA branch region. Genes Dev. 1994 Dec 15; 8(24):3008-20. PMID: 8001820.
    Citations: 80     Fields:    Translation:HumansCells
  148. Ezaz-Nikpay K, Verdine GL. The effects of N7-methylguanine on duplex DNA structure. Chem Biol. 1994 Dec; 1(4):235-40. PMID: 9383396.
    Citations: 14     Fields:    Translation:Cells
  149. Erlanson DA, Verdine GL. Falling out of the fold: tumorigenic mutations and p53. Chem Biol. 1994 Oct; 1(2):79-84. PMID: 9383374.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  150. Myers LC, Cushing TD, Wagner G, Verdine GL. Metal-coordination sphere in the methylated Ada protein-DNA co-complex. Chem Biol. 1994 Oct; 1(2):91-7. PMID: 9383376.
    Citations: 4     Fields:    Translation:Cells
  151. Liu J, Fan QR, Sodeoka M, Lane WS, Verdine GL. DNA binding by an amino acid residue in the C-terminal half of the Rel homology region. Chem Biol. 1994 Sep; 1(1):47-55. PMID: 9383370.
    Citations:    Fields:    
  152. Bestor TH, Verdine GL. DNA methyltransferases. Curr Opin Cell Biol. 1994 Jun; 6(3):380-9. PMID: 7917329.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  153. Reinisch KM, Chen L, Verdine GL, Lipscomb WN. Crystallization and preliminary crystallographic analysis of a DNA (cytosine-5)-methyltransferase from Haemophilus aegyptius bound covalently to DNA. J Mol Biol. 1994 May 13; 238(4):626-9. PMID: 8176750.
    Citations: 1     Fields:    Translation:Cells
  154. Liu J, Sodeoka M, Lane WS, Verdine GL. Evidence for a non-alpha-helical DNA-binding motif in the Rel homology region. Proc Natl Acad Sci U S A. 1994 Feb 01; 91(3):908-12. PMID: 8302865.
    Citations: 12     Fields:    Translation:HumansCells
  155. Verdine GL. The flip side of DNA methylation. Cell. 1994 Jan 28; 76(2):197-200. PMID: 8293456.
    Citations: 14     Fields:    Translation:Cells
  156. Ezaz-Nikpay K, Uchino K, Lerner RE, Verdine GL. Construction of an overproduction vector containing the novel srp (sterically repressed) promoter. Protein Sci. 1994 Jan; 3(1):132-8. PMID: 8142890.
    Citations: 9     Fields:    Translation:Cells
  157. Myers LC, Verdine GL, Wagner G. Solution structure of the DNA methyl phosphotriester repair domain of Escherichia coli Ada. Biochemistry. 1993 Dec 28; 32(51):14089-94. PMID: 8260490.
    Citations: 13     Fields:    Translation:Cells
  158. Jain J, McCaffrey PG, Miner Z, Kerppola TK, Lambert JN, Verdine GL, Curran T, Rao A. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature. 1993 Sep 23; 365(6444):352-5. PMID: 8397339.
    Citations: 248     Fields:    Translation:AnimalsCells
  159. Potter DA, Larson CJ, Eckes P, Schmid RM, Nabel GJ, Verdine GL, Sharp PA. Purification of the major histocompatibility complex class I transcription factor H2TF1. The full-length product of the nfkb2 gene. J Biol Chem. 1993 Sep 05; 268(25):18882-90. PMID: 8360178.
    Citations: 5     Fields:    Translation:HumansCells
  160. Myers LC, Terranova MP, Ferentz AE, Wagner G, Verdine GL. Repair of DNA methylphosphotriesters through a metalloactivated cysteine nucleophile. Science. 1993 Aug 27; 261(5125):1164-7. PMID: 8395079.
    Citations: 24     Fields:    Translation:Cells
  161. MacFerrin KD, Chen L, Terranova MP, Schreiber SL, Verdine GL. Overproduction of proteins using expression-cassette polymerase chain reaction. Methods Enzymol. 1993; 217:79-102. PMID: 8474353.
    Citations: 7     Fields:    Translation:HumansCells
  162. Hayashibara KC, Verdine GL. Template-directed interference footprinting of cytosine contacts in a protein-DNA complex: potent interference by 5-aza-2'-deoxycytidine. Biochemistry. 1992 Nov 24; 31(46):11265-73. PMID: 1280158.
    Citations: 5     Fields:    Translation:Cells
  163. Larson CJ, Verdine GL. A high-capacity column for affinity purification of sequence-specific DNA-binding proteins. Nucleic Acids Res. 1992 Jul 11; 20(13):3525. PMID: 1630934.
    Citations: 10     Fields:    Translation:Cells
  164. Myers LC, Terranova MP, Nash HM, Markus MA, Verdine GL. Zinc binding by the methylation signaling domain of the Escherichia coli Ada protein. Biochemistry. 1992 May 19; 31(19):4541-7. PMID: 1581309.
    Citations: 13     Fields:    Translation:Cells
  165. Chen L, MacMillan AM, Chang W, Ezaz-Nikpay K, Lane WS, Verdine GL. Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase. Biochemistry. 1991 Nov 19; 30(46):11018-25. PMID: 1932026.
    Citations: 94     Fields:    Translation:Cells
  166. Standaert RF, Galat A, Verdine GL, Schreiber SL. Molecular cloning and overexpression of the human FK506-binding protein FKBP. Nature. 1990 Aug 16; 346(6285):671-4. PMID: 1696686.
    Citations: 89     Fields:    Translation:HumansCells
  167. MacFerrin KD, Terranova MP, Schreiber SL, Verdine GL. Overproduction and dissection of proteins by the expression-cassette polymerase chain reaction. Proc Natl Acad Sci U S A. 1990 Mar; 87(5):1937-41. PMID: 2408046.
    Citations: 25     Fields:    Translation:HumansCells
  168. Shewchuk LM, Verdine GL, Nash H, Walsh CT. Mutagenesis of the cysteines in the metalloregulatory protein MerR indicates that a metal-bridged dimer activates transcription. Biochemistry. 1989 Jul 25; 28(15):6140-5. PMID: 2551364.
    Citations: 9     Fields:    Translation:Cells
  169. Shewchuk LM, Verdine GL, Walsh CT. Transcriptional switching by the metalloregulatory MerR protein: initial characterization of DNA and mercury (II) binding activities. Biochemistry. 1989 Mar 07; 28(5):2331-9. PMID: 2719955.
    Citations: 16     Fields:    Translation:Cells
  170. Walsh CT, Distefano MD, Moore MJ, Shewchuk LM, Verdine GL. Molecular basis of bacterial resistance to organomercurial and inorganic mercuric salts. FASEB J. 1988 Feb; 2(2):124-30. PMID: 3277886.
    Citations: 23     Fields:    Translation:Cells
  171. Tomasz M, Lipman R, Lee MS, Verdine GL, Nakanishi K. Reaction of acid-activated mitomycin C with calf thymus DNA and model guanines: elucidation of the base-catalyzed degradation of N7-alkylguanine nucleosides. Biochemistry. 1987 Apr 07; 26(7):2010-27. PMID: 3109476.
    Citations: 21     Fields:    
  172. Tomasz M, Lipman R, Chowdary D, Pawlak J, Verdine GL, Nakanishi K. Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science. 1987 Mar 06; 235(4793):1204-8. PMID: 3103215.
    Citations: 86     Fields:    
  173. Tomasz M, Chowdary D, Lipman R, Shimotakahara S, Veiro D, Walker V, Verdine GL. Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct. Proc Natl Acad Sci U S A. 1986 Sep; 83(18):6702-6. PMID: 3018744.
    Citations: 32     Fields:    Translation:Cells
  174. Tomasz M, Lipman R, Verdine GL, Nakanishi K. Reassignment of the guanine-binding mode of reduced mitomycin C. Biochemistry. 1986 Jul 29; 25(15):4337-44. PMID: 3092855.
    Citations: 6     Fields:    
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: FAS faculty should contact the Office for Scholarly Communication (oschulmail.harvard.edu) for general questions about Profiles. For data questions, please contact Raelyn Lincoln (raelyn_lincolnharvard.edu) from the FAS Division of Science; Jennifer Shephard (jmshephfas.harvard.edu) from the FAS Division of Social Science; or Alexander Parker (afparkerfas.harvard.edu) from the FAS Division of Arts and Humanities.
Verdine's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (542)
Co-Authors (22)
Similar People (60)
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.