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Irene Emily Kochevar, Ph.D.

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Research
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  1. R01AR043895 (KOCHEVAR, IRENE E) Jul 10, 1996 - Jun 30, 2005
    NIH/NIAMS
    MECHANISMS FOR CHRONIC UVR-INDUCED DAMAGE TO SKIN
    Role: Principal Investigator
  2. R01GM030755 (KOCHEVAR, IRENE E) Sep 1, 1981 - May 31, 2005
    NIH/NIGMS
    Ultraviolet Light Induced Phenomena in Biomembranes
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Germann JA, Martínez-Enríquez E, Martínez-García MC, Kochevar IE, Marcos S. Corneal Collagen Ordering After In Vivo Rose Bengal and Riboflavin Cross-Linking. Invest Ophthalmol Vis Sci. 2020 03 09; 61(3):28. PMID: 32186674.
    Citations:    
  2. Redmond RW, Kochevar IE. Medical Applications of Rose Bengal- and Riboflavin-Photosensitized Protein Crosslinking. Photochem Photobiol. 2019 09; 95(5):1097-1115. PMID: 31111489.
    Citations:    
  3. Kwok SJJ, Forward S, Wertheimer CM, Liapis AC, Lin HH, Kim M, Seiler TG, Birngruber R, Kochevar IE, Seiler T, Yun SH. Selective Equatorial Sclera Crosslinking in the Orbit Using a Metal-Coated Polymer Waveguide. Invest Ophthalmol Vis Sci. 2019 06 03; 60(7):2563-2570. PMID: 31212308.
    Citations:    
  4. Wertheimer CM, Elhardt C, Kaminsky SM, Pham L, Pei Q, Mendes B, Afshar S, Kochevar IE. Enhancing Rose Bengal-Photosensitized Protein Crosslinking in the Cornea. Invest Ophthalmol Vis Sci. 2019 05 01; 60(6):1845-1852. PMID: 31042790.
    Citations:    
  5. Lorenzo-Martín E, Gallego-Muñoz P, Ibares-Frías L, Marcos S, Pérez-Merino P, Fernández I, Kochevar IE, Martínez-García MC. Rose Bengal and Green Light Versus Riboflavin-UVA Cross-Linking: Corneal Wound Repair Response. Invest Ophthalmol Vis Sci. 2018 10 01; 59(12):4821-4830. PMID: 30347076.
    Citations:    Fields:    
  6. Soeken TA, Zhu H, DeMartelaere S, Davies BW, Kim M, Wang HC, Aden J, Grimm R, Alt C, Kochevar IE, Johnson AJ. Sealing of Corneal Lacerations Using Photoactivated Rose Bengal Dye and Amniotic Membrane. Cornea. 2018 Feb; 37(2):211-217. PMID: 29140861.
    Citations:    Fields:    Translation:Animals
  7. Seiler TG, Engler M, Beck E, Birngruber R, Kochevar IE. Interface Bonding With Corneal Crosslinking (CXL) After LASIK Ex Vivo. Invest Ophthalmol Vis Sci. 2017 12 01; 58(14):6292-6298. PMID: 29242903.
    Citations:    Fields:    Translation:Animals
  8. Alarcon EI, Poblete H, Roh H, Couture JF, Comer J, Kochevar IE. Rose Bengal Binding to Collagen and Tissue Photobonding. ACS Omega. 2017 Oct 31; 2(10):6646-6657. PMID: 31457260.
    Citations:    
  9. Ortega-Martinez A, Touchette G, Zhu H, Kochevar IE, Franco W. Variations in the endogenous fluorescence of rabbit corneas after mechanical property alterations. J Biomed Opt. 2017 Sep; 22(9):1-7. PMID: 28933070.
    Citations:    Fields:    Translation:Animals
  10. Gallego-Muñoz P, Ibares-Frías L, Lorenzo E, Marcos S, Peréz-Merino P, Bekesi N, Kochevar IE, Martínez-García MC. Corneal Wound Repair After Rose Bengal and Green Light Crosslinking: Clinical and Histologic Study. Invest Ophthalmol Vis Sci. 2017 07 01; 58(9):3471-3480. PMID: 28700779.
    Citations: 2     Fields:    Translation:Animals
  11. Senthil-Kumar P, Ng-Glazier JH, Randolph MA, Bodugoz-Senturk H, Muratoglu OK, Kochevar IE, Winograd JM, Redmond RW. An intraluminal stent facilitates light-activated vascular anastomosis. J Trauma Acute Care Surg. 2017 07; 83(1 Suppl 1):S43-S49. PMID: 28383474.
    Citations:    Fields:    Translation:Animals
  12. Kwok SJJ, Kim M, Lin HH, Seiler TG, Beck E, Shao P, Kochevar IE, Seiler T, Yun SH. Flexible Optical Waveguides for Uniform Periscleral Cross-Linking. Invest Ophthalmol Vis Sci. 2017 05 01; 58(5):2596-2602. PMID: 28494493.
    Citations: 4     Fields:    Translation:Animals
  13. Pupkaite J, Ahumada M, Mclaughlin S, Temkit M, Alaziz S, Seymour R, Ruel M, Kochevar I, Griffith M, Suuronen EJ, Alarcon EI. Collagen-Based Photoactive Agent for Tissue Bonding. ACS Appl Mater Interfaces. 2017 Mar 22; 9(11):9265-9270. PMID: 28282110.
    Citations:    Fields:    Translation:Animals
  14. Bekesi N, Gallego-Muñoz P, Ibarés-Frías L, Perez-Merino P, Martinez-Garcia MC, Kochevar IE, Marcos S. Biomechanical Changes After In Vivo Collagen Cross-Linking With Rose Bengal-Green Light and Riboflavin-UVA. Invest Ophthalmol Vis Sci. 2017 03 01; 58(3):1612-1620. PMID: 28297026.
    Citations: 2     Fields:    Translation:Animals
  15. Zhu H, Kochevar IE, Behlau I, Zhao J, Wang F, Wang Y, Sun X, Hamblin MR, Dai T. Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies. Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):586-593. PMID: 28129422.
    Citations: 2     Fields:    Translation:AnimalsCells
  16. Fadlallah A, Zhu H, Arafat S, Kochevar I, Melki S, Ciolino JB. Corneal Resistance to Keratolysis After Collagen Crosslinking With Rose Bengal and Green Light. Invest Ophthalmol Vis Sci. 2016 12 01; 57(15):6610-6614. PMID: 27926752.
    Citations: 1     Fields:    Translation:Animals
  17. Zhu H, Alt C, Webb RH, Melki S, Kochevar IE. Corneal Crosslinking With Rose Bengal and Green Light: Efficacy and Safety Evaluation. Cornea. 2016 Sep; 35(9):1234-41. PMID: 27362877.
    Citations: 2     Fields:    Translation:AnimalsCells
  18. Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Kochevar IE, Winograd JM, Redmond RW. Erratum: Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury. J Reconstr Microsurg. 2016 11; 32(9):e1. PMID: 27341523.
    Citations:    Fields:    
  19. Liu C, Vojnovic D, Kochevar IE, Jurkunas UV. UV-A Irradiation Activates Nrf2-Regulated Antioxidant Defense and Induces p53/Caspase3-Dependent Apoptosis in Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2016 Apr 01; 57(4):2319-27. PMID: 27127932.
    Citations: 6     Fields:    Translation:HumansCells
  20. Senthil-Kumar P, Ni T, Randolph MA, Velmahos GC, Kochevar IE, Redmond RW. A light-activated amnion wrap strengthens colonic anastomosis and reduces peri-anastomotic adhesions. Lasers Surg Med. 2016 07; 48(5):530-7. PMID: 26996284.
    Citations:    Fields:    Translation:HumansAnimals
  21. Bekesi N, Kochevar IE, Marcos S. Corneal Biomechanical Response Following Collagen Cross-Linking With Rose Bengal-Green Light and Riboflavin-UVA. Invest Ophthalmol Vis Sci. 2016 Mar; 57(3):992-1001. PMID: 26968733.
    Citations: 4     Fields:    Translation:Animals
  22. Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Kochevar IE, Winograd JM, Redmond RW. Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury. J Reconstr Microsurg. 2016 Jul; 32(6):421-30. PMID: 26878685.
    Citations:    Fields:    Translation:AnimalsCells
  23. Marcos S, Alejandre N, Lamela J, Dorronsoro C, Kochevar IE. Toward New Engagement Paradigms For Intraocular Lenses: Light-Initiated Bonding of Capsular Bag to Lens Materials. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4249-56. PMID: 26161986.
    Citations: 1     Fields:    Translation:Animals
  24. Xu N, Yao M, Farinelli W, Hajjarian Z, Wang Y, Redmond RW, Kochevar IE. Light-activated sealing of skin wounds. Lasers Surg Med. 2015 Jan; 47(1):17-29. PMID: 25418831.
    Citations: 3     Fields:    Translation:Animals
  25. Liu C, Chen Y, Kochevar IE, Jurkunas UV. Decreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2014 Jul 31; 55(9):5551-60. PMID: 25082883.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  26. Yao M, Gu C, Doyle FJ, Zhu H, Redmond RW, Kochevar IE. Why is rose bengal more phototoxic to fibroblasts in vitro than in vivo? Photochem Photobiol. 2014 Mar-Apr; 90(2):297-305. PMID: 24266530.
    Citations: 4     Fields:    Translation:HumansCells
  27. Cherfan D, Verter EE, Melki S, Gisel TE, Doyle FJ, Scarcelli G, Yun SH, Redmond RW, Kochevar IE. Collagen cross-linking using rose bengal and green light to increase corneal stiffness. Invest Ophthalmol Vis Sci. 2013 May 13; 54(5):3426-33. PMID: 23599326.
    Citations: 10     Fields:    Translation:AnimalsCells
  28. Ni T, Senthil-Kumar P, Dubbin K, Aznar-Cervantes SD, Datta N, Randolph MA, Cenis JL, Rutledge GC, Kochevar IE, Redmond RW. A photoactivated nanofiber graft material for augmented Achilles tendon repair. Lasers Surg Med. 2012 Oct; 44(8):645-52. PMID: 22911554.
    Citations: 5     Fields:    Translation:AnimalsCells
  29. Tsao S, Yao M, Tsao H, Henry FP, Zhao Y, Kochevar JJ, Redmond RW, Kochevar IE. Light-activated tissue bonding for excisional wound closure: a split-lesion clinical trial. Br J Dermatol. 2012 Mar; 166(3):555-63. PMID: 22032650.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  30. Yang P, Yao M, DeMartelaere SL, Redmond RW, Kochevar IE. Light-activated sutureless closure of wounds in thin skin. Lasers Surg Med. 2012 Feb; 44(2):163-7. PMID: 22170339.
    Citations: 3     Fields:    Translation:AnimalsCells
  31. Verter EE, Gisel TE, Yang P, Johnson AJ, Redmond RW, Kochevar IE. Light-initiated bonding of amniotic membrane to cornea. Invest Ophthalmol Vis Sci. 2011 Dec 09; 52(13):9470-7. PMID: 22058339.
    Citations: 4     Fields:    Translation:HumansAnimals
  32. Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D. In vivo evaluation of demyelination and remyelination in a nerve crush injury model. Biomed Opt Express. 2011 Sep 01; 2(9):2698-708. PMID: 22091449.
    Citations: 22     
  33. Wang Y, Kochevar IE, Redmond RW, Yao M. A light-activated method for repair of corneal surface defects. Lasers Surg Med. 2011 Aug; 43(6):481-9. PMID: 21761418.
    Citations: 1     Fields:    Translation:Animals
  34. Gu C, Ni T, Verter EE, Redmond RW, Kochevar IE, Yao M. Photochemical tissue bonding: a potential strategy for treating limbal stem cell deficiency. Lasers Surg Med. 2011 Jul; 43(5):433-42. PMID: 21674548.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  35. Franco RA, Dowdall JR, Bujold K, Amann C, Faquin W, Redmond RW, Kochevar IE. Photochemical repair of vocal fold microflap defects. Laryngoscope. 2011 Jun; 121(6):1244-51. PMID: 21480282.
    Citations: 4     Fields:    Translation:AnimalsCells
  36. Venditti E, Brugè F, Astolfi P, Kochevar I, Damiani E. Nitroxides and a nitroxide-based UV filter have the potential to photoprotect UVA-irradiated human skin fibroblasts against oxidative damage. J Dermatol Sci. 2011 Jul; 63(1):55-61. PMID: 21530182.
    Citations: 3     Fields:    Translation:HumansCells
  37. Yao M, Yaroslavsky A, Henry FP, Redmond RW, Kochevar IE. Phototoxicity is not associated with photochemical tissue bonding of skin. Lasers Surg Med. 2010 Feb; 42(2):123-31. PMID: 20166159.
    Citations: 12     Fields:    Translation:AnimalsCells
  38. Choi WS, Mitsumoto A, Kochevar IE. Involvement of reactive oxygen species in TGF-beta1-induced tropoelastin expression by human dermal fibroblasts. Photochem Photobiol. 2009 Nov-Dec; 85(6):1425-33. PMID: 19709383.
    Citations: 4     Fields:    Translation:HumansCells
  39. O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Preparation and integration of human amnion nerve conduits using a light-activated technique. Plast Reconstr Surg. 2009 Aug; 124(2):428-37. PMID: 19644257.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  40. Yamaura M, Yao M, Yaroslavsky I, Cohen R, Smotrich M, Kochevar IE. Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes. Lasers Surg Med. 2009 Apr; 41(4):282-90. PMID: 19347944.
    Citations: 32     Fields:    Translation:HumansCells
  41. Henry FP, Côté D, Randolph MA, Rust EA, Redmond RW, Kochevar IE, Lin CP, Winograd JM. Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg. 2009 Feb; 123(2 Suppl):123S-30S. PMID: 19182671.
    Citations: 21     Fields:    Translation:Animals
  42. Henry FP, Goyal NA, David WS, Wes D, Bujold KE, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Improving electrophysiologic and histologic outcomes by photochemically sealing amnion to the peripheral nerve repair site. Surgery. 2009 Mar; 145(3):313-21. PMID: 19231584.
    Citations: 7     Fields:    Translation:HumansAnimals
  43. Ibusuki S, Papadopoulos A, Ranka MP, Halbesma GJ, Randolph MA, Redmond RW, Kochevar IE, Gill TJ. Engineering cartilage in a photochemically crosslinked collagen gel. J Knee Surg. 2009 Jan; 22(1):72-81. PMID: 19216355.
    Citations: 8     Fields:    Translation:AnimalsCells
  44. O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Photochemical sealing improves outcome following peripheral neurorrhaphy. J Surg Res. 2009 Jan; 151(1):33-9. PMID: 18599081.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  45. O'Neill AC, Winograd JM, Zeballos JL, Johnson TS, Randolph MA, Bujold KE, Kochevar IE, Redmond RW. Microvascular anastomosis using a photochemical tissue bonding technique. Lasers Surg Med. 2007 Oct; 39(9):716-22. PMID: 17960755.
    Citations: 8     Fields:    Translation:Animals
  46. Ibusuki S, Halbesma GJ, Randolph MA, Redmond RW, Kochevar IE, Gill TJ. Photochemically cross-linked collagen gels as three-dimensional scaffolds for tissue engineering. Tissue Eng. 2007 Aug; 13(8):1995-2001. PMID: 17518705.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  47. Valencia A, Kochevar IE. Nox1-based NADPH oxidase is the major source of UVA-induced reactive oxygen species in human keratinocytes. J Invest Dermatol. 2008 Jan; 128(1):214-22. PMID: 17611574.
    Citations: 36     Fields:    Translation:HumansCells
  48. Johnson TS, O'Neill AC, Motarjem PM, Amann C, Nguyen T, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Photochemical tissue bonding: a promising technique for peripheral nerve repair. J Surg Res. 2007 Dec; 143(2):224-9. PMID: 17543988.
    Citations: 6     Fields:    Translation:AnimalsCells
  49. Bargagna-Mohan P, Mohan R, Russo L, Kochevar IE, Fini ME. Cell lines and transgenic mice expressing a matrix metalloproteinase-9 promoter-driven reporter gene: potential for assay of ultraviolet light effects and light-inhibiting compounds. Cutan Ocul Toxicol. 2007; 26(4):383-97. PMID: 18058311.
    Citations:    Fields:    Translation:AnimalsCells
  50. Valencia A, Rajadurai A, Carle AB, Kochevar IE. 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts. Free Radic Biol Med. 2006 Dec 01; 41(11):1704-18. PMID: 17145559.
    Citations: 13     Fields:    Translation:HumansCells
  51. Redmond RW, Kochevar IE. Spatially resolved cellular responses to singlet oxygen. Photochem Photobiol. 2006 Sep-Oct; 82(5):1178-86. PMID: 16740059.
    Citations: 52     Fields:    Translation:HumansCells
  52. Valencia A, Kochevar IE. Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome. Free Radic Biol Med. 2006 Feb 15; 40(4):641-50. PMID: 16458195.
    Citations: 15     Fields:    Translation:HumansCells
  53. Kamegaya Y, Farinelli WA, Vila Echague AV, Akita H, Gallagher J, Flotte TJ, Anderson RR, Redmond RW, Kochevar IE. Evaluation of photochemical tissue bonding for closure of skin incisions and excisions. Lasers Surg Med. 2005 Oct; 37(4):264-70. PMID: 16196042.
    Citations: 4     Fields:    Translation:Animals
  54. Chan BP, Amann C, Yaroslavsky AN, Title C, Smink D, Zarins B, Kochevar IE, Redmond RW. Photochemical repair of Achilles tendon rupture in a rat model. J Surg Res. 2005 Apr; 124(2):274-9. PMID: 15820258.
    Citations: 7     Fields:    Translation:Animals
  55. Wang H, Kochevar IE. Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes. Free Radic Biol Med. 2005 Apr 01; 38(7):890-7. PMID: 15749385.
    Citations: 20     Fields:    Translation:HumansCells
  56. Proano CE, Azar DT, Mocan MC, Redmond RW, Kochevar IE. Photochemical keratodesmos as an adjunct to sutures for bonding penetrating keratoplasty corneal incisions. J Cataract Refract Surg. 2004 Nov; 30(11):2420-4. PMID: 15519099.
    Citations: 3     Fields:    Translation:Animals
  57. Proaño CE, Mulroy L, Jones E, Azar DT, Redmond RW, Kochevar IE. Photochemical keratodesmos for bonding corneal incisions. Invest Ophthalmol Vis Sci. 2004 Jul; 45(7):2177-81. PMID: 15223792.
    Citations: 3     Fields:    Translation:Animals
  58. Kochevar IE. Singlet oxygen signaling: from intimate to global. Sci STKE. 2004 Feb 17; 2004(221):pe7. PMID: 14983102.
    Citations: 20     Fields:    Translation:AnimalsCells
  59. Kossodo S, Wong WR, Simon G, Kochevar IE. Effects of UVR and UVR-induced cytokines on production of extracellular matrix proteins and proteases by dermal fibroblasts cultured in collagen gels%. Photochem Photobiol. 2004 Jan; 79(1):86-93. PMID: 14974720.
    Citations: 3     Fields:    Translation:HumansCells
  60. Zhuang S, Kochevar IE. Singlet oxygen-induced activation of Akt/protein kinase B is independent of growth factor receptors. Photochem Photobiol. 2003 Oct; 78(4):361-71. PMID: 14626664.
    Citations: 12     Fields:    Translation:AnimalsCells
  61. Nguyen BC, Kochevar IE. Factors influencing sunless tanning with dihydroxyacetone. Br J Dermatol. 2003 Aug; 149(2):332-40. PMID: 12932240.
    Citations: 1     Fields:    Translation:Humans
  62. Zhuang S, Ouedraogo GD, Kochevar IE. Downregulation of epidermal growth factor receptor signaling by singlet oxygen through activation of caspase-3 and protein phosphatases. Oncogene. 2003 Jul 10; 22(28):4413-24. PMID: 12853978.
    Citations: 11     Fields:    Translation:HumansCells
  63. Zhuang S, Kochevar IE. Ultraviolet A radiation induces rapid apoptosis of human leukemia cells by Fas ligand-independent activation of the Fas death pathways. Photochem Photobiol. 2003 Jul; 78(1):61-7. PMID: 12929750.
    Citations: 8     Fields:    Translation:HumansCells
  64. Nguyen BC, Kochevar IE. Influence of hydration on dihydroxyacetone-induced pigmentation of stratum corneum. J Invest Dermatol. 2003 Apr; 120(4):655-61. PMID: 12648231.
    Citations: 2     Fields:    Translation:Animals
  65. Chan BP, Kochevar IE, Redmond RW. Enhancement of porcine skin graft adherence using a light-activated process. J Surg Res. 2002 Nov; 108(1):77-84. PMID: 12443718.
    Citations: 7     Fields:    Translation:Animals
  66. Zhuang S, Demirs JT, Kochevar IE. Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation. Oncogene. 2001 Oct 11; 20(46):6764-76. PMID: 11709711.
    Citations: 3     Fields:    Translation:HumansCells
  67. Wong WR, Kossodo S, Kochevar IE. Influence of cytokines on matrix metalloproteinases produced by fibroblasts cultured in monolayer and collagen gels. J Formos Med Assoc. 2001 Jun; 100(6):377-82. PMID: 11480246.
    Citations: 6     Fields:    Translation:HumansCells
  68. Mulroy L, Kim J, Wu I, Scharper P, Melki SA, Azar DT, Redmond RW, Kochevar IE. Photochemical keratodesmos for repair of lamellar corneal incisions. Invest Ophthalmol Vis Sci. 2000 Oct; 41(11):3335-40. PMID: 11006222.
    Citations: 5     Fields:    Translation:Animals
  69. Kochevar IE, Lynch MC, Zhuang S, Lambert CR. Singlet oxygen, but not oxidizing radicals, induces apoptosis in HL-60 cells. Photochem Photobiol. 2000 Oct; 72(4):548-53. PMID: 11045728.
    Citations: 9     Fields:    Translation:HumansCells
  70. Tartier L, McCarey YL, Biaglow JE, Kochevar IE, Held KD. Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria. Cell Death Differ. 2000 Oct; 7(10):1002-10. PMID: 11279547.
    Citations: 11     Fields:    Translation:HumansCells
  71. Lin CP, Lynch MC, Kochevar IE. Reactive oxidizing species produced near the plasma membrane induce apoptosis in bovine aorta endothelial cells. Exp Cell Res. 2000 Sep 15; 259(2):351-9. PMID: 10964502.
    Citations: 5     Fields:    Translation:AnimalsCells
  72. Zhuang S, Demirs JT, Kochevar IE. p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem. 2000 Aug 25; 275(34):25939-48. PMID: 10837470.
    Citations: 55     Fields:    Translation:HumansCells
  73. Kochevar IE, Redmond RW. Photosensitized production of singlet oxygen. Methods Enzymol. 2000; 319:20-8. PMID: 10907495.
    Citations: 22     Fields:    Translation:AnimalsCells
  74. Gonzalez S, Moran M, Kochevar IE. Chronic photodamage in skin of mast cell-deficient mice. Photochem Photobiol. 1999 Aug; 70(2):248-53. PMID: 10461464.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  75. Zhuang S, Lynch MC, Kochevar IE. Caspase-8 mediates caspase-3 activation and cytochrome c release during singlet oxygen-induced apoptosis of HL-60 cells. Exp Cell Res. 1999 Jul 10; 250(1):203-12. PMID: 10388534.
    Citations: 16     Fields:    Translation:HumansCells
  76. Ibbotson SH, Moran MN, Nash JF, Kochevar IE. The effects of radicals compared with UVB as initiating species for the induction of chronic cutaneous photodamage. J Invest Dermatol. 1999 Jun; 112(6):933-8. PMID: 10383741.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Kochevar IE, Garcia C, Geacintov NE. Photoaddition to DNA by nonintercalated chlorpromazine molecules. Photochem Photobiol. 1998 Nov; 68(5):692-7. PMID: 9825699.
    Citations: 4     Fields:    Translation:Cells
  78. Kollias N, Gillies R, Moran M, Kochevar IE, Anderson RR. Endogenous skin fluorescence includes bands that may serve as quantitative markers of aging and photoaging. J Invest Dermatol. 1998 Nov; 111(5):776-80. PMID: 9804337.
    Citations: 13     Fields:    Translation:Animals
  79. So P, Kim H, Kochevar I. Two-Photon deep tissue ex vivo imaging of mouse dermal and subcutaneous structures. Opt Express. 1998 Oct 26; 3(9):339-50. PMID: 19384379.
    Citations: 19     Fields:    
  80. Zhuang S, Lynch MC, Kochevar IE. Activation of protein kinase C is required for protection of cells against apoptosis induced by singlet oxygen. FEBS Lett. 1998 Oct 16; 437(1-2):158-62. PMID: 9804192.
    Citations: 3     Fields:    Translation:HumansCells
  81. Ibbotson SH, Lambert CR, Moran MN, Lynch MC, Kochevar IE. Benzoyl peroxide increases UVA-induced plasma membrane damage and lipid oxidation in murine leukemia L1210 cells. J Invest Dermatol. 1998 Jan; 110(1):79-83. PMID: 9424093.
    Citations: 1     Fields:    Translation:AnimalsCells
  82. Moor AC, Lagerberg JW, Tijssen K, Foley S, Truscott TG, Kochevar IE, Brand A, Dubbelman TM, VanSteveninck J. In vitro fluence rate effects in photodynamic reactions with AIPcS4 as sensitizer. Photochem Photobiol. 1997 Dec; 66(6):860-5. PMID: 9421972.
    Citations: 2     Fields:    Translation:HumansCells
  83. Lambert CR, Kochevar IE. Electron transfer quenching of the rose bengal triplet state. Photochem Photobiol. 1997 Jul; 66(1):15-25. PMID: 9230700.
    Citations: 5     Fields:    Translation:Cells
  84. Schomacker KT, Walsh A, Gregory KW, Kochevar IE. Cell damage induced by Angiovist-370 and 308nm excimer laser radiation. Lasers Surg Med. 1997; 20(2):111-8. PMID: 9047164.
    Citations:    Fields:    Translation:HumansCells
  85. Stiel H, Teuchner K, Paul A, Leupold D, Kochevar IE. Quantitative comparison of excited state properties and intensity- dependent photosensitization by rose bengal. J Photochem Photobiol B. 1996 May; 33(3):245-54. PMID: 8683400.
    Citations: 4     Fields:    
  86. Kochevar IE, Lambert CR, Lynch MC, Tedesco AC. Comparison of photosensitized plasma membrane damage caused by singlet oxygen and free radicals. Biochim Biophys Acta. 1996 Apr 26; 1280(2):223-30. PMID: 8639697.
    Citations: 9     Fields:    Translation:AnimalsCells
  87. Lambert CR, Stiel H, Leupold D, Lynch MC, Kochevar IE. Intensity-dependent enzyme photosensitization using 532 nm nanosecond laser pulses. Photochem Photobiol. 1996 Feb; 63(2):154-60. PMID: 8657729.
    Citations: 4     Fields:    Translation:HumansCells
  88. Kochevar IE, Bouvier J, Lynch M, Lin CW. Influence of dye and protein location on photosensitization of the plasma membrane. Biochim Biophys Acta. 1994 Dec 30; 1196(2):172-80. PMID: 7841181.
    Citations: 14     Fields:    Translation:AnimalsCells
  89. Kochevar IE, Moran M, Granstein RD. Experimental photoaging in C3H/HeN, C3H/HeJ, and Balb/c mice: comparison of changes in extracellular matrix components and mast cell numbers. J Invest Dermatol. 1994 Dec; 103(6):797-800. PMID: 7798617.
    Citations: 3     Fields:    Translation:Animals
  90. Smith G, McGimpsey WG, Lynch MC, Kochevar IE, Redmond RW. An efficient oxygen independent two-photon photosensitization mechanism. Photochem Photobiol. 1994 Feb; 59(2):135-9. PMID: 8165232.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  91. Andley UP, Lewis RM, Reddan JR, Kochevar IE. Action spectrum for cytotoxicity in the UVA- and UVB-wavelength region in cultured lens epithelial cells. Invest Ophthalmol Vis Sci. 1994 Feb; 35(2):367-73. PMID: 8112983.
    Citations: 13     Fields:    Translation:AnimalsCells
  92. Chaudhry H, Lynch M, Schomacker K, Birngruber R, Gregory K, Kochevar I. Relaxation of vascular smooth muscle induced by low-power laser radiation. Photochem Photobiol. 1993 Nov; 58(5):661-9. PMID: 8284321.
    Citations: 1     Fields:    Translation:Animals
  93. Gut IG, Farmer R, Huang RC, Kochevar IE. Upper excited state photochemistry of DNA. Photochem Photobiol. 1993 Sep; 58(3):313-7. PMID: 8234462.
    Citations:    Fields:    
  94. Kochevar IE, Moran M, Lyon N, Flotte T, Siebert E, Gange RW. Effects of systemic indomethacin, meclizine, and BW755C on chronic ultraviolet B-induced effects in hairless mouse skin. J Invest Dermatol. 1993 Feb; 100(2):186-93. PMID: 8429241.
    Citations: 2     Fields:    Translation:Animals
  95. Dunn DA, Lin VH, Kochevar IE. Base-selective oxidation and cleavage of DNA by photochemical cosensitized electron transfer. Biochemistry. 1992 Nov 24; 31(46):11620-5. PMID: 1445897.
    Citations: 3     Fields:    Translation:Cells
  96. Allen MT, Lynch M, Lagos A, Redmond RW, Kochevar IE. A wavelength dependent mechanism for rose bengal-sensitized photoinhibition of red cell acetylcholinesterase. Biochim Biophys Acta. 1991 Sep 02; 1075(1):42-9. PMID: 1892865.
    Citations: 3     Fields:    Translation:HumansCells
  97. Kochevar IE, Walsh AA, Green HA, Sherwood M, Shih AG, Sutherland BM. DNA damage induced by 193-nm radiation in mammalian cells. Cancer Res. 1991 Jan 01; 51(1):288-93. PMID: 1988091.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  98. Dunn DA, Lin VH, Kochevar IE. The role of ground state complexation in the electron transfer quenching of methylene blue fluorescence by purine nucleotides. Photochem Photobiol. 1991 Jan; 53(1):47-56. PMID: 2027906.
    Citations: 3     Fields:    Translation:Cells
  99. Andley UP, Walsh A, Kochevar IE, Reddan JR. Effect of ultraviolet-B radiation on protein synthesis in cultured lens epithelial cells. Curr Eye Res. 1990 Nov; 9(11):1099-106. PMID: 2095321.
    Citations: 10     Fields:    Translation:AnimalsCells
  100. Kochevar IE. UV-induced protein alterations and lipid oxidation in erythrocyte membranes. Photochem Photobiol. 1990 Oct; 52(4):795-800. PMID: 2089428.
    Citations: 5     Fields:    Translation:HumansCells
  101. Kochevar IE, Walsh AA, Held KD, Gallo RL, Mirro J. Mechanism for 193-nm laser radiation-induced effects on mammalian cells. Radiat Res. 1990 May; 122(2):142-8. PMID: 2336460.
    Citations: 1     Fields:    Translation:AnimalsCells
  102. Kochevar IE, Buckley LA. Photochemistry of DNA using 193 nm excimer laser radiation. Photochem Photobiol. 1990 May; 51(5):527-32. PMID: 2367550.
    Citations:    Fields:    
  103. Gendimenico GJ, Kochevar IE. A further characterization of acridine-photosensitized inhibition of mast cell degranulation. Photodermatol Photoimmunol Photomed. 1990 Apr; 7(2):51-5. PMID: 2400675.
    Citations:    Fields:    Translation:AnimalsCells
  104. Gallo RL, Kochevar IE, Granstein RD. Ultraviolet radiation induces a change in cell membrane potential in vitro: a possible signal for ultraviolet radiation induced alteration in cell activity. Photochem Photobiol. 1989 May; 49(5):655-62. PMID: 2474173.
    Citations: 3     Fields:    Translation:Cells
  105. Fluhler EN, Hurley JK, Kochevar IE. Laser intensity and wavelength dependence of Rose-Bengal-photosensitized inhibition of red blood cell acetylcholinesterase. Biochim Biophys Acta. 1989 Mar 24; 990(3):269-75. PMID: 2923906.
    Citations: 4     Fields:    Translation:HumansCells
  106. Ciulla TA, Van Camp JR, Rosenfeld E, Kochevar IE. Photosensitization of single-strand breaks in pBR322 DNA by rose bengal. Photochem Photobiol. 1989 Mar; 49(3):293-8. PMID: 2734367.
    Citations: 1     Fields:    Translation:Cells
  107. Kochevar IE. Cytotoxicity and mutagenicity of excimer laser radiation. Lasers Surg Med. 1989; 9(5):440-5. PMID: 2682102.
    Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  108. Valdes-Aguilera O, Ara G, Kochevar IE. Phototoxicity mechanism of a kryptocyanine dye in human red cell membranes and isolated murine mitochondria. Cancer Res. 1988 Dec 01; 48(23):6794-8. PMID: 3180089.
    Citations:    Fields:    Translation:HumansAnimalsCells
  109. Morison WL, Hood AF, Kochevar IE. Piroxicam-induced photosensitivity. J Am Acad Dermatol. 1987 Oct; 17(4):698-9. PMID: 2959688.
    Citations:    Fields:    Translation:Humans
  110. Western A, Van Camp JR, Bensasson R, Land EJ, Kochevar IE. Involvement of singlet oxygen in the phototoxicity mechanism for a metabolite of piroxicam. Photochem Photobiol. 1987 Oct; 46(4):469-75. PMID: 3423119.
    Citations: 4     Fields:    Translation:HumansCells
  111. Green HA, Margolis R, Boll J, Kochevar IE, Parrish JA, Oseroff AR. Unscheduled DNA synthesis in human skin after in vitro ultraviolet-excimer laser ablation. J Invest Dermatol. 1987 Aug; 89(2):201-4. PMID: 3598211.
    Citations:    Fields:    Translation:Humans
  112. Kochevar IE. Mechanisms of drug photosensitization. Photochem Photobiol. 1987 Jun; 45(6):891-5. PMID: 3306725.
    Citations: 5     Fields:    Translation:HumansAnimals
  113. Valdes-Aguilera O, Cincotta L, Foley J, Kochevar IE. Photobleaching of a cyanine dye in solution and in membranes. Photochem Photobiol. 1987 Mar; 45(3):337-44. PMID: 3562590.
    Citations:    Fields:    Translation:HumansCells
  114. Green H, Boll J, Parrish JA, Kochevar IE, Oseroff AR. Cytotoxicity and mutagenicity of low intensity, 248 and 193 nm excimer laser radiation in mammalian cells. Cancer Res. 1987 Jan 15; 47(2):410-3. PMID: 3791231.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  115. Kochevar IE, Morison WL, Lamm JL, McAuliffe DJ, Western A, Hood AF. Possible mechanism of piroxicam-induced photosensitivity. Arch Dermatol. 1986 Nov; 122(11):1283-7. PMID: 3777974.
    Citations:    Fields:    Translation:HumansAnimals
  116. Ciulla TA, Epling GA, Kochevar IE. Photoaddition of chlorpromazine to guanosine-5'-monophosphate. Photochem Photobiol. 1986 Jun; 43(6):607-13. PMID: 3018805.
    Citations: 3     Fields:    Translation:Animals
  117. Kochevar IE. Photobiology. Basic science. Dermatol Clin. 1986 Apr; 4(2):171-9. PMID: 3955889.
    Citations:    Fields:    Translation:Humans
  118. Gange RW, Blackett AD, Matzinger EA, Sutherland BM, Kochevar IE. Comparative protection efficiency of UVA- and UVB-induced tans against erythema and formation of endonuclease-sensitive sites in DNA by UVB in human skin. J Invest Dermatol. 1985 Oct; 85(4):362-4. PMID: 3840189.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  119. Kochevar IE. Action spectrum and mechanisms of UV radiation-induced injury in lupus erythematosus. J Invest Dermatol. 1985 Jul; 85(1 Suppl):140s-143s. PMID: 2409182.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  120. Hasan T, Kochevar IE, Abdulah D. Amiodarone phototoxicity to human erythrocytes and lymphocytes. Photochem Photobiol. 1984 Dec; 40(6):715-9. PMID: 6522459.
    Citations:    Fields:    Translation:HumansCells
  121. Gendimenico GJ, Kochevar IE. Degranulation of mast cells and inhibition of the response to secretory agents by phototoxic compounds and ultraviolet radiation. Toxicol Appl Pharmacol. 1984 Nov; 76(2):374-82. PMID: 6495341.
    Citations: 2     Fields:    Translation:AnimalsCells
  122. Kochevar IE, Chung FL, Jeffrey AM. Photoaddition of chlorpromazine to DNA. Chem Biol Interact. 1984 Oct; 51(3):273-84. PMID: 6488389.
    Citations: 3     Fields:    Translation:AnimalsCells
  123. Hasan T, Kochevar IE, McAuliffe DJ, Cooperman BS, Abdulah D. Mechanism of tetracycline phototoxicity. J Invest Dermatol. 1984 Sep; 83(3):179-83. PMID: 6470521.
    Citations: 6     Fields:    Translation:HumansCells
  124. Kochevar IE, Hoover KW, Gawienowski M. Benoxaprofen photosensitization of cell membrane disruption. J Invest Dermatol. 1984 Mar; 82(3):214-8. PMID: 6699424.
    Citations: 1     Fields:    Translation:HumansCells
  125. Kochevar IE, Gange RW. Cutaneous photobiology. Photochem Photobiol. 1983 Jun; 37(6):695-700. PMID: 6611675.
    Citations:    Fields:    Translation:Humans
  126. Kochevar IE, Yoon M. Photosensitization of methyl linoleate oxidation by tryptophan in peptides. Photochem Photobiol. 1983 Mar; 37(3):279-85. PMID: 6844424.
    Citations:    Fields:    Translation:Cells
  127. Kochevar IE, Hom J. Photoproducts of chlorpromazine which cause red blood cell lysis. Photochem Photobiol. 1983 Feb; 37(2):163-8. PMID: 6844420.
    Citations: 5     Fields:    Translation:HumansCells
  128. Kochevar IE, Armstrong RB, Einbinder J, Walther RR, Harber LC. Coal tar phototoxicity: active compounds and action spectra. Photochem Photobiol. 1982 Jul; 36(1):65-9. PMID: 7111440.
    Citations: 2     Fields:    Translation:Animals
  129. Gasparro FP, Kochevar IE. Investigation of protriptyline photoproducts which cause cell membrane disruption. Photochem Photobiol. 1982 Mar; 35(3):351-8. PMID: 7063551.
    Citations:    Fields:    Translation:HumansCells
  130. Lamola AA, Landon DO, Kochevar IE, Harber LC. An instrument for action spectrum studies in dermatology. Photochem Photobiol. 1982 Feb; 35(2):285-90. PMID: 7063547.
    Citations:    Fields:    Translation:HumansAnimals
  131. Giovinazzo VJ, Ichikawa H, Kochevar IE, Armstrong RB, Harber LC. Photoallergic contact dermatitis to musk ambrette: action spectra in guinea pigs and man. Photochem Photobiol. 1981 May; 33(5):773-7. PMID: 7267727.
    Citations: 1     Fields:    Translation:HumansAnimals
  132. Giovinazzo VJ, Harber LC, Armstrong RB, Kochevar IE. Photoallergic contact dermatitis to musk ambrette. Clinical report of two patients with persistent light reactor patterns. J Am Acad Dermatol. 1980 Oct; 3(4):384-93. PMID: 7430459.
    Citations: 1     Fields:    Translation:Humans
  133. Sutherland BM, Harber LC, Kochevar IE. Pyrimidine dimer formation and repair in human skin. Cancer Res. 1980 Sep; 40(9):3181-5. PMID: 6253056.
    Citations: 16     Fields:    Translation:HumansCells
  134. Kochevar IE. Possible mechanisms of toxicity due to photochemical products of protriptyline. Toxicol Appl Pharmacol. 1980 Jun 30; 54(2):258-64. PMID: 7423492.
    Citations: 1     Fields:    Translation:HumansAnimals
  135. Kochevar IE. Photoallergic responses to chemicals. Photochem Photobiol. 1979 Oct; 30(4):437-42. PMID: 315567.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  136. Kochevar IE, Lamola AA. Chlorpromazine and protriptyline phototoxicity: photosensitized, oxygen independent red cell hemolysis. Photochem Photobiol. 1979 Apr; 29(4):791-6. PMID: 451017.
    Citations: 5     Fields:    Translation:HumansCells
  137. Kochevar IE, Harber LC. Photoreactions of 3,3',4',5-tetrachlorosalicylanilide with proteins. J Invest Dermatol. 1977 Mar; 68(3):151-6. PMID: 14216.
    Citations: 3     Fields:    Translation:HumansCells
  138. Kochevar IE. Photochemistry of molecules of biological interest. Photochem Photobiol. 1976 Dec; 24(6):661-2. PMID: 1087979.
    Citations:    Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.