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profileJohn Isaac Loewenstein, M.D.

TitleAssociate Professor of Ophthalmology
InstitutionMassachusetts Eye and Ear Infirmary
DepartmentOphthalmology
AddressMassachusetts Eye & Ear Infrm
Ophthalmology
243 Charles St
Boston MA 02114
Phone617/573-4274
Fax617/573-3698
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Roohipoor R, Yaseri M, Teymourpour A, Kloek C, Miller JB, Loewenstein JI. Early Performance on an Eye Surgery Simulator Predicts Subsequent Resident Surgical Performance. J Surg Educ. 2017 Apr 20. PMID: 28434885.
    View in: PubMed
  2. Gaier ED, Miller JB, Loewenstein JI. Combined Central Retinal Vein Occlusion and Central Retinal Arterial Obstruction with Cilioretinal Artery Sparing. Ophthalmology. 2017 Apr; 124(4):576. PMID: 28335940.
    View in: PubMed
  3. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2016 Jun; 166:206-207. PMID: 27084591.
    View in: PubMed
  4. Roohipoor R, Karkhaneh R, Farahani A, Ebrahimiadib N, Modjtahedi B, Fotouhi A, Yaseri M, Khodabande A, Zarei M, Imani Fuladi M, Taheri A, Riazi Esfahani M, Loewenstein J. Retinopathy of prematurity screening criteria in Iran: new screening guidelines. Arch Dis Child Fetal Neonatal Ed. 2016 Jul; 101(4):F288-93. PMID: 27073259.
    View in: PubMed
  5. Vavvas DG, Daniels AB, Kapsala ZG, Goldfarb JW, Ganotakis E, Loewenstein JI, Young LH, Gragoudas ES, Eliott D, Kim IK, Tsilimbaris MK, Miller JW. Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment. EBioMedicine. 2016 Mar; 5:198-203. PMID: 27077128; PMCID: PMC4816836.
  6. Roohipoor R, Loewenstein JI. Need for Refinement of International Retinopathy of Prematurity Guidelines and Classifications. J Ophthalmic Vis Res. 2015 Oct-Dec; 10(4):355-7. PMID: 27051477; PMCID: PMC4795382.
  7. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2015 Dec; 160(6):1255-1258.e1. PMID: 26393438.
    View in: PubMed
  8. Chee YE, Newman LR, Loewenstein JI, Kloek CE. Improving the Teaching Skills of Residents in a Surgical Training Program: Results of the Pilot Year of a Curricular Initiative in an Ophthalmology Residency Program. J Surg Educ. 2015 Sep-Oct; 72(5):890-7. PMID: 25921191.
    View in: PubMed
  9. Liu Y, Magro C, Loewenstein JI, Makar RS, Stowell CP, Dzik WH, Hochberg EP, Oaklander AL, Sobrin L. A Man with Paraneoplastic Retinopathy plus Small Fiber Polyneuropathy Associated with Waldenström Macroglobulinemia (Lymphoplasmacytic Lymphoma): Insights into Mechanisms. Ocul Immunol Inflamm. 2015; 23(5):405-9. PMID: 24654565.
    View in: PubMed
  10. Faez S, Loewenstein JI, Sobrin L. Detection of antiretinal autoantibodies in serum by Western blotting--reply. JAMA Ophthalmol. 2013 Oct; 131(10):1371-2. PMID: 24114140.
    View in: PubMed
  11. Kloek CE, Borboli-Gerogiannis S, Chang K, Kuperwaser M, Newman LR, Lane AM, Loewenstein JI. A broadly applicable surgical teaching method: evaluation of a stepwise introduction to cataract surgery. J Surg Educ. 2014 Mar-Apr; 71(2):169-75. PMID: 24602704.
    View in: PubMed
  12. Yonekawa Y, Andreoli C, Miller JB, Loewenstein JI, Sobrin L, Eliott D, Vavvas DG, Miller JW, Kim IK. Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration. Am J Ophthalmol. 2013 Jul; 156(1):29-35.e2. PMID: 23668679.
    View in: PubMed
  13. Faez S, Loewenstein J, Sobrin L. Concordance of antiretinal antibody testing results between laboratories in autoimmune retinopathy. JAMA Ophthalmol. 2013 Jan; 131(1):113-5. PMID: 23307224.
    View in: PubMed
  14. Comander J, Loewenstein J, Sobrin L. Diagnostic testing and disease monitoring in birdshot chorioretinopathy. Semin Ophthalmol. 2011 Jul-Sep; 26(4-5):329-36. PMID: 21958183.
    View in: PubMed
  15. Comander J, Gardiner M, Loewenstein J. High-resolution optical coherence tomography findings in solar maculopathy and the differential diagnosis of outer retinal holes. Am J Ophthalmol. 2011 Sep; 152(3):413-419.e6. PMID: 21708377.
    View in: PubMed
  16. Henderson BA, Kim JY, Golnik KC, Oetting TA, Lee AG, Volpe NJ, Aaron M, Uhler TA, Arnold A, Dunn JP, Prajna NV, Lane AM, Loewenstein JI. Evaluation of the virtual mentor cataract training program. Ophthalmology. 2010 Feb; 117(2):253-8. PMID: 19969355.
    View in: PubMed
  17. Chen J, Shah HA, Herbert C, Loewenstein JI, Rizzo JF. Extraction of a chronically implanted, microfabricated, subretinal electrode array. Ophthalmic Res. 2009; 42(3):128-37. PMID: 19590253.
    View in: PubMed
  18. Liu Y, Dinkin MJ, Loewenstein JI, Rizzo JF, Cestari DM. Multifocal electroretinographic abnormalities in ethambutol-induced visual loss. J Neuroophthalmol. 2008 Dec; 28(4):278-82. PMID: 19145124.
    View in: PubMed
  19. de Bruin DM, Burnes DL, Loewenstein J, Chen Y, Chang S, Chen TC, Esmaili DD, de Boer JF. In vivo three-dimensional imaging of neovascular age-related macular degeneration using optical frequency domain imaging at 1050 nm. Invest Ophthalmol Vis Sci. 2008 Oct; 49(10):4545-52. PMID: 18390638.
    View in: PubMed
  20. Huynh N, Akbari M, Loewenstein JI. Tactile feedback in Cataract and Retinal Surgery: A Survey-Based Study. Journal of Academic Ophthalmology. 2008; 1(2):79-85.
  21. Ahmed E, Loewenstein J. Leber congenital amaurosis: disease, genetics and therapy. Semin Ophthalmol. 2008 Jan-Feb; 23(1):39-43. PMID: 18214790.
    View in: PubMed
  22. Singh RP, Hatton M, Sprich S, Loewenstein J. Posttraumatic stress. Ophthalmology. 2007 Jun; 114(6):1238. PMID: 17544795.
    View in: PubMed
  23. Ho J, Loewenstein JI. Endophthalmitis associated with intravitreal injections. Int Ophthalmol Clin. 2007; 47(2):199-208. PMID: 17450019.
    View in: PubMed
  24. S.Chang, J.F. de Boer, M. de Bruin, A. Yun, D. Burns. Optical Frequency Domain Imaging: High Speed OCT at 1050 nm to Image Choroidal Neovascularization in Age-Related Macular Degereation Patients. Inv Ophthalmol Vis Sci Suppl. 2007; 48:135.
  25. Andreoli CM, Husain D, Davis TS, Loewenstein JI. Chorioretinal changes heralding metastatic malignancy. Arch Ophthalmol. 2006 Dec; 124(12):1790-2. PMID: 17159048.
    View in: PubMed
  26. Warden SM, Pachydaki SI, Christoforidis JB, D'Amico DJ, Loewenstein JI. Choroidal neovascularization after epiretinal membrane removal. Arch Ophthalmol. 2006 Nov; 124(11):1652-4. PMID: 17102017.
    View in: PubMed
  27. Montezuma SR, Loewenstein J, Scholz C, Rizzo JF. Biocompatibility of materials implanted into the subretinal space of Yucatan pigs. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3514-22. PMID: 16877423.
    View in: PubMed
  28. Ament CS, Zacks DN, Lane AM, Krzystolik M, D'Amico DJ, Mukai S, Young LH, Loewenstein J, Arroyo J, Miller JW. Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture. Arch Ophthalmol. 2006 Jul; 124(7):957-66. PMID: 16832018.
    View in: PubMed
  29. Henderson BA, Neaman A, Kim BH, Loewenstein J. Virtual training tool. Ophthalmology. 2006 Jun; 113(6):1058-9. PMID: 16751045.
    View in: PubMed
  30. Krzystolik MG, Filippopoulos T, Ducharme JF, Loewenstein JI. Pegaptanib as an adjunctive treatment for complicated neovascular diabetic retinopathy. Arch Ophthalmol. 2006 Jun; 124(6):920-1. PMID: 16769855.
    View in: PubMed
  31. T. Fillippopoulos, J.F. Ducharme, J.I. Loewenstein, M.G. Krzytolik. Antiangiogenic Agents as an Adjunctive Treatment for Complicated Neovascular Glaucoma. Inv Ophthalmol Vis Sci Suppl. 2006; 47:4476.
  32. Durand ML, Kim IK, D'Amico DJ, Loewenstein JI, Tobin EH, Kieval SJ, Martin SS, Azar DT, Miller FS, Lujan BJ, Miller JW. Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin. Am J Ophthalmol. 2005 Sep; 140(3):552-4. PMID: 16139017.
    View in: PubMed
  33. M.D. Gingerich, D.B. Shire, J. Chen, J. Loewenstein, H.A. Shah, J. Sun, J.L. Wyatt, J.F. Rizzo. Surgical Guides for Electrode Implantation Into the Subretinal Space. Inv Ophthalmol Vis Sci Suppl. 2005; 46:1494.
  34. J. Chen, J. Loewenstein, H.A. Shah, C.D. Herbert, J.F. Rizzo. Extraction of a Chronically Implanted Sub-Retinal Electrode Array. Inv Ophthalmol Vis Sci Suppl. 2005; 46:1488.
  35. Lee MS, Gupta N, Penson RT, Loewenstein J, Wepner MS, Seiden MV, Milam AH. Cone damage in patients receiving high-dose irofulven treatment. Arch Ophthalmol. 2005 Jan; 123(1):29-34. PMID: 15642808.
    View in: PubMed
  36. R. Singh, M. Hatton, S. Sprich, J. Loewenstein. Post Traumatic Stress Disorder and Depressive Symptoms After Open Globe Injuries. Inv Ophthalmol Vis Sci Suppl. 2005; 46:5031.
  37. Hatton MP, Loewenstein J. Attrition from ophthalmology residency programs. Am J Ophthalmol. 2004 Nov; 138(5):863-4. PMID: 15531325.
    View in: PubMed
  38. Ray S, Friberg TA, Beatty RR, Loewenstein J. Late posterior migration of glass intraocular foreign bodies. Arch Ophthalmol. 2004 Jun; 122(6):923-6. PMID: 15197073.
    View in: PubMed
  39. Loewenstein JI, Montezuma SR, Rizzo JF. Outer retinal degeneration: an electronic retinal prosthesis as a treatment strategy. Arch Ophthalmol. 2004 Apr; 122(4):587-96. PMID: 15078678.
    View in: PubMed
  40. Loewenstein JI, Warden SM, Rizzo JF. Visual Prostheses. Hartnett ME, ed. Pediatric Retinal Disease: Medical and Surgical Approaches. 2004.
  41. Rizzo JF, Wyatt JL, Loewenstein J, Montezuma S, Shire DB, Theogarajan L, Kelly SK. Development of a wireless, ab externo retinal prosthesis. Inv. Ophthalmol. Vis Sci Suppl. 2004; 45:45.
  42. Sun JK, Montezuma SR, Loewenstein J, Rizzo JF. Progress toward a minimally invasive ab externo technique for subretinal prosthetic implantation. Inv. Ophthalmol. Vis Sci Suppl. 2004; 45:4190.
  43. Reddy HS, Loewenstein JI, Lane A, Shen L. Peripapillary choroidal neovascularization. Inv. Ophthalmol. Vis Sci Suppl. 2004; 45:3077.
  44. Husain D, Loewenstein JI. Surgical approaches to retinal prosthesis implantation. Int Ophthalmol Clin. 2004; 44(1):105-11. PMID: 14704525.
    View in: PubMed
  45. Montezuma SR, Loewenstein J, Scholz C, Rizzo JF. Biocompatibility of subretinal materials in Yucatan pigs. Inv. Ophthalmol. Vis Sci Suppl. 2004; 45:4169.
  46. Iaccheri B, Fiore T, Androudi S, Papadaki T, Loewenstein JI, Miller JW, Young LHY, D’Amico D, Foster CS. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE): final outcome and visual prognosis. Inv. Ophthalmol. Vis. Sci. Suppl. 2004; 45:2692.
  47. Rizzo JF, Wyatt J, Loewenstein J, Kelly S, Shire D. Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials. Invest Ophthalmol Vis Sci. 2003 Dec; 44(12):5362-9. PMID: 14638739.
    View in: PubMed
  48. Rizzo JF, Wyatt J, Loewenstein J, Kelly S, Shire D. Methods and perceptual thresholds for short-term electrical stimulation of human retina with microelectrode arrays. Invest Ophthalmol Vis Sci. 2003 Dec; 44(12):5355-61. PMID: 14638738.
    View in: PubMed
  49. Ray S, Loewenstein J. Atypical manifestation of multiple evanescent white dot syndrome with large peripapillary lesion. Arch Ophthalmol. 2003 Dec; 121(12):1794-6. PMID: 14662606.
    View in: PubMed
  50. Shire DB, Gingerich M, Theogarajan L, Wyatt J, Loewenstein J, Montezuma S, Rizzo J. Packaging development for retinal prosthesis. Inv. Ophthalmol. Vis Sci Suppl. 2003; 44:S210.
  51. Lee MS, Gupta N, Loewenstein JI, Wepner M, Milam AM. Retinal cone toxicity in an ovarian cancer patient treated with Irofulven. Inv. Ophthalmol. Vis Sci Suppl. 2003; 44:S21.
  52. Loewenstein JI and Lee S, editors. Ophthalmology: Just the Facts. 2003.
  53. Rizzo JF, Jensen RJ, Loewenstein J, Wyatt J. Unexpectedly small percepts evoked by epi-retinal electrical stimulation in blind humans. Inv. Ophthalmol. Vis Sci Suppl. . 2003; 44:S174.
  54. Loewenstein JI. Vitreous, Retina, and Choroid. Loewenstein JI and Lee S, eds. Ophthalmology: Just the Facts. 2003.
  55. Reddy HS, Loewenstein JI. Visual Function. Loewenstein JI and Lee S, eds. Ophthalmology: Just the Facts. 2003.
  56. EyeTech Study Group. Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration. Ophthalmology. 2003; 240:601-7.
  57. Zacks DN, Samson CM, Loewenstein J, Foster CS. Electroretinograms as an indicator of disease activity in birdshot retinochoroidopathy. Graefes Arch Clin Exp Ophthalmol. 2002 Aug; 240(8):601-7. PMID: 12192452.
    View in: PubMed
  58. Loewenstein JI, Rizzo JF, Montezuma SR. Implantation of subretinal polyimide in Yucatan pigs. . Inv ophthalmol Vis Sci Suppl. 2002; 43:S178.
  59. Ament CS, Zacks D, Lane AM, D’Amico DJ, Young L, Mukai S, Loewenstein J,Gragoudas E, Arroyo J, Miller J . Traumatic choroidal rupture: visual outcome and treatment of choroidal vascular membranes. . Inv. Ophthalmol. Vis Sci Suppl. . 2002; 43:S179.
  60. Shire DB, Rizzo JF, Loewenstein JI. Micromachined tacks to attach a prosthesis to the retina. . Inv Ophthalmol Vis Sci Suppl. 2002; 43:S179.
  61. Shahin ME, Rizzo JF, Wyatt J, Loewenstein J. Evaluation of external electrical stimulation studies. Inv Ophthalmol Vis Sci Suppl. 2000; 40:S860.
  62. Loewenstein J. Retinopathy associated with blood anomalies. Albert D, Jakobiec F, editors. Principles and Practice of Ophthalmology. 1999.
  63. Rizzo JF, Loewenstein J, Wyatt J. Development of an Epiretinal Electronic Visual Prosthesis. Hollyfield JG, ANderson RE, LaVail MM, eds. Retinal Degenerative Diseases and Experimental Therapy. 1999; 463-469.
  64. Friedman D Loewenstein J. Strategies for improving the physician-patient relatoinship. Albert D, Jakobiec F. Principles and Practice of Ophthalmology. 1999.
  65. Kim RY, Loewenstein JI. Systemic diseases manifesting as exudative retinal detachment. Int Ophthalmol Clin. 1998; 38(1):177-95. PMID: 9532481.
    View in: PubMed
  66. Loewenstein J, editor. Managed Care. International Ophthalmology Clinics. 1998.
  67. Loewenstein JI. Introduction to capitation. Int Ophthalmol Clin. 1998; 38(3):101-6. PMID: 9742438.
    View in: PubMed
  68. Loewenstein JI. Overview of quality measurement and improvement. Int Ophthalmol Clin. 1998; 38(3):59-68. PMID: 9742433.
    View in: PubMed
  69. Loewenstein JI. Clinical practice guidelines. Int Ophthalmol Clin. 1998; 38(3):75-85. PMID: 9742435.
    View in: PubMed
  70. Harris EW, Loewenstein JI, Azar D. Vitamin A deficiency and its effects on the eye. Int Ophthalmol Clin. 1998; 38(1):155-61. PMID: 9532479.
    View in: PubMed
  71. Loewenstein JI, Hogan RN, Jakobiec FA. Osseous metaplasia in a preretinal membrane. Arch Ophthalmol. 1997 Jan; 115(1):117-9. PMID: 9006438.
    View in: PubMed
  72. Schwarz T, Loewenstein J, Isenberg KE. Maintenance ECT: indications and outcome. Convuls Ther. 1995 Mar; 11(1):14-23. PMID: 7796063.
    View in: PubMed
  73. Loewenstein JI. Bilateral macular holes in von Hippel-Lindau disease. Arch Ophthalmol. 1995 Feb; 113(2):143-4. PMID: 7864744.
    View in: PubMed
  74. Loewenstein JI. Visual hallucinations in patients with choroidal neovascularization. JAMA. 1994 Jul 20; 272(3):243. PMID: 7517460.
    View in: PubMed
  75. Loewenstein J. Eye Emergencies. Noble J, ed. Textbook of General Medicine and Priamry Care. 1987; 689-703.
  76. Loewenstein J, editor, section on ophthalmology; In Noble J, editor. Textbook of General Medicine and Primary Care. 1987; 683-743.
  77. Loewenstein J. The Eye in Systemic Disease. Noble J, ed. Textbook of General Medicine and Priamry Care. 1987; 737-743.
  78. Loewenstein J. The Ocular Examination. Noble J, ed. Textbook of General Medicine and Priamry Care. 1987; 683-687.
  79. Loewenstein J, Putnoi D. Common Ocular Problems. Noble J, ed. Textbook of General Medicine and Priamry Care. 1987; 705-722.
  80. Loewenstein JI, Palmberg PF, Connett JE, Wentworth DN. Effectiveness of a pinhole method for visual acuity screening. Arch Ophthalmol. 1985 Feb; 103(2):222-3. PMID: 3977693.
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  81. Loewenstein J. Abnormal Visual Phenomona. Clinical Experience. 1984; 1:12-21.
  82. Loewenstein J. Vitrectomy. Snow JC Ed. Anesthesia in Otolaryngology and Ophthalmology. 1982.
  83. Lubin JR, Loewenstein JI, Frederick AR. Vogt-Koyanagi-Harada syndrome with focal neurologic signs. Am J Ophthalmol. 1981 Mar; 91(3):332-41. PMID: 7211990.
    View in: PubMed
  84. Leibowitz HM, Krueger DE, Maunder LR, Milton RC, Kini MM, Kahn HA, Nickerson RJ, Pool J, Colton TL, Ganley JP, Loewenstein JI, Dawber TR. The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975. Surv Ophthalmol. 1980 May-Jun; 24(Suppl):335-610. PMID: 7444756.
    View in: PubMed
  85. Green GJ, Lessell S, Loewenstein JI. Ischemic optic neuropathy in chronic papilledema. Arch Ophthalmol. 1980 Mar; 98(3):502-4. PMID: 7362508.
    View in: PubMed
  86. Loewenstein JI, Lessell S. Experimental cryosurgical lesion of the optic nerve. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1980; 215(2):97-103. PMID: 6908462.
    View in: PubMed
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