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Tom Bernhardt, Ph.D.

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Other Positions
Title
Institution
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Mentoring
completed student projects
Cell Wall Endopeptidases in Pseudomonas aeruginosa
Part Time, 01/20/17 - 12/20/17

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. R13AI138540 (BERNHARDT, THOMAS G) Mar 1, 2018 - Feb 28, 2019
    NIH/NIAID
    2018 Boston Bacterial Meeting (2018)
    Role: Principal Investigator
  2. R13AI131601 (BERNHARDT, THOMAS G) May 3, 2017 - Apr 30, 2018
    NIH/NIAID
    2017 Boston Bacterial Meeting (BBM)
    Role: Principal Investigator
  3. R13AI124565 (BERNHARDT, THOMAS G) Jun 1, 2016 - May 31, 2017
    NIH/NIAID
    Bacterial Meeting 2016-2021
    Role: Principal Investigator
  4. U19AI109764 (KASPER, DENNIS L.) Mar 1, 2014 - Jun 30, 2019
    NIH
    Innovative Platforms for Antimicrobial Therapy and Vaccine Development
    Role: Co-Principal Investigator
  5. R33AI111713 (BERNHARDT, THOMAS G) Mar 1, 2014 - Feb 28, 2019
    NIH/NIAID
    Targeting cell separation systems of gram-negative bacteria.
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Rohs PDA, Bernhardt TG. Growth and Division of the Peptidoglycan Matrix. Annu Rev Microbiol. 2021 10 08; 75:315-336. PMID: 34351794.
    Citations: 7     Fields:    Translation:Cells
  2. Marmont LS, Bernhardt TG. A conserved subcomplex within the bacterial cytokinetic ring activates cell wall synthesis by the FtsW-FtsI synthase. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23879-23885. PMID: 32907942.
    Citations: 11     Fields:    Translation:Cells
  3. Truong TT, Vettiger A, Bernhardt TG. Cell division is antagonized by the activity of peptidoglycan endopeptidases that promote cell elongation. Mol Microbiol. 2020 12; 114(6):966-978. PMID: 32866331.
    Citations: 3     Fields:    Translation:Cells
  4. Fivenson EM, Bernhardt TG. An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in Escherichia coli. mBio. 2020 05 19; 11(3). PMID: 32430473.
    Citations: 19     Fields:    Translation:Cells
  5. Sher JW, Lim HC, Bernhardt TG. Global phenotypic profiling identifies a conserved actinobacterial cofactor for a bifunctional PBP-type cell wall synthase. Elife. 2020 03 13; 9. PMID: 32167475.
    Citations: 6     Fields:    Translation:Cells
  6. Yakhnina AA, Bernhardt TG. The Tol-Pal system is required for peptidoglycan-cleaving enzymes to complete bacterial cell division. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6777-6783. PMID: 32152098; PMCID: PMC7104345.
    Citations: 20     Fields:    Translation:Cells
  7. Sjodt M, Rohs PDA, Gilman MSA, Erlandson SC, Zheng S, Green AG, Brock KP, Taguchi A, Kahne D, Walker S, Marks DS, Rudner DZ, Bernhardt TG, Kruse AC. Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nat Microbiol. 2020 06; 5(6):813-820. PMID: 32152588.
    Citations: 27     Fields:    Translation:Cells
  8. Lim HC, Bernhardt TG. A PopZ-linked apical recruitment assay for studying protein-protein interactions in the bacterial cell envelope. Mol Microbiol. 2019 12; 112(6):1757-1768. PMID: 31550057.
    Citations: 7     Fields:    Translation:Cells
  9. Lim HC, Sher JW, Rodriguez-Rivera FP, Fumeaux C, Bertozzi CR, Bernhardt TG. Identification of new components of the RipC-FtsEX cell separation pathway of Corynebacterineae. PLoS Genet. 2019 08; 15(8):e1008284. PMID: 31437147.
    Citations: 10     Fields:    Translation:Cells
  10. Flores-Kim J, Dobihal GS, Fenton A, Rudner DZ, Bernhardt TG. A switch in surface polymer biogenesis triggers growth-phase-dependent and antibiotic-induced bacteriolysis. Elife. 2019 04 09; 8. PMID: 30964003; PMCID: PMC6456293.
    Citations: 18     Fields:    Translation:Cells
  11. Taguchi A, Welsh MA, Marmont LS, Lee W, Sjodt M, Kruse AC, Kahne D, Bernhardt TG, Walker S. FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein. Nat Microbiol. 2019 04; 4(4):587-594. PMID: 30692671; PMCID: PMC6430707.
    Citations: 101     Fields:    Translation:Cells
  12. Zhou X, Rodriguez-Rivera FP, Lim HC, Bell JC, Bernhardt TG, Bertozzi CR, Theriot JA. Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum. Nat Chem Biol. 2019 03; 15(3):221-231. PMID: 30664686; PMCID: PMC6693342.
    Citations: 9     Fields:    Translation:Cells
  13. Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG. Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery. Antimicrob Agents Chemother. 2019 01; 63(1). PMID: 30323039; PMCID: PMC6325226.
    Citations: 8     Fields:    Translation:Cells
  14. Rohs PDA, Buss J, Sim SI, Squyres GR, Srisuknimit V, Smith M, Cho H, Sjodt M, Kruse AC, Garner EC, Walker S, Kahne DE, Bernhardt TG. A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery. PLoS Genet. 2018 10; 14(10):e1007726. PMID: 30335755; PMCID: PMC6207328.
    Citations: 48     Fields:    Translation:Cells
  15. Baranowski C, Welsh MA, Sham LT, Eskandarian HA, Lim HC, Kieser KJ, Wagner JC, McKinney JD, Fantner GE, Ioerger TR, Walker S, Bernhardt TG, Rubin EJ, Rego EH. Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape. Elife. 2018 10 16; 7. PMID: 30324906; PMCID: PMC6231781.
    Citations: 42     Fields:    Translation:Cells
  16. Sham LT, Zheng S, Yakhnina AA, Kruse AC, Bernhardt TG. Loss of specificity variants of WzxC suggest that substrate recognition is coupled with transporter opening in MOP-family flippases. Mol Microbiol. 2018 09; 109(5):633-641. PMID: 29907971; PMCID: PMC6181778.
    Citations: 7     Fields:    Translation:Cells
  17. Zheng S, Sham LT, Rubino FA, Brock KP, Robins WP, Mekalanos JJ, Marks DS, Bernhardt TG, Kruse AC. Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):6709-6714. PMID: 29891673; PMCID: PMC6042122.
    Citations: 22     Fields:    Translation:Cells
  18. Sjodt M, Brock K, Dobihal G, Rohs PDA, Green AG, Hopf TA, Meeske AJ, Srisuknimit V, Kahne D, Walker S, Marks DS, Bernhardt TG, Rudner DZ, Kruse AC. Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis. Nature. 2018 04 05; 556(7699):118-121. PMID: 29590088.
    Citations: 41     Fields:    Translation:Cells
  19. Greene NG, Fumeaux C, Bernhardt TG. Conserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):3150-3155. PMID: 29507210; PMCID: PMC5866570.
    Citations: 19     Fields:    Translation:Cells
  20. Fenton AK, Manuse S, Flores-Kim J, Garcia PS, Mercy C, Grangeasse C, Bernhardt TG, Rudner DZ. Phosphorylation-dependent activation of the cell wall synthase PBP2a in Streptococcus pneumoniae by MacP. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):2812-2817. PMID: 29487215; PMCID: PMC5856526.
    Citations: 19     Fields:    Translation:Cells
  21. Chamakura KR, Sham LT, Davis RM, Min L, Cho H, Ruiz N, Bernhardt TG, Young R. A viral protein antibiotic inhibits lipid II flippase activity. Nat Microbiol. 2017 Nov; 2(11):1480-1484. PMID: 28894177.
    Citations: 14     Fields:    Translation:Cells
  22. Lai GC, Cho H, Bernhardt TG. The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli. PLoS Genet. 2017 Jul; 13(7):e1006934. PMID: 28749938; PMCID: PMC5549755.
    Citations: 35     Fields:    Translation:Cells
  23. Pang T, Wang X, Lim HC, Bernhardt TG, Rudner DZ. The nucleoid occlusion factor Noc controls DNA replication initiation in Staphylococcus aureus. PLoS Genet. 2017 Jul; 13(7):e1006908. PMID: 28723932.
    Citations: 16     Fields:    Translation:Cells
  24. Tsang MJ, Yakhnina AA, Bernhardt TG. NlpD links cell wall remodeling and outer membrane invagination during cytokinesis in Escherichia coli. PLoS Genet. 2017 Jul; 13(7):e1006888. PMID: 28708841; PMCID: PMC5533458.
    Citations: 42     Fields:    Translation:Cells
  25. Fumeaux C, Bernhardt TG. Identification of MupP as a New Peptidoglycan Recycling Factor and Antibiotic Resistance Determinant in Pseudomonas aeruginosa. mBio. 2017 03 28; 8(2). PMID: 28351916; PMCID: PMC5371409.
    Citations: 10     Fields:    Translation:Cells
  26. Buss JA, Peters NT, Xiao J, Bernhardt TG. ZapA and ZapB form an FtsZ-independent structure at midcell. Mol Microbiol. 2017 05; 104(4):652-663. PMID: 28249098; PMCID: PMC5426985.
    Citations: 25     Fields:    Translation:Cells
  27. Fenton AK, El Mortaji L, Lau DT, Rudner DZ, Bernhardt TG. Erratum: CozE is a member of the MreCD complex that directs cell elongation in Streptococcus pneumoniae. Nat Microbiol. 2017 Jan 23; 2:17011. PMID: 28112724.
    Citations: 2     Fields:    
  28. Fenton AK, El Mortaji L, Lau DT, Rudner DZ, Bernhardt TG. CozE is a member of the MreCD complex that directs cell elongation in Streptococcus pneumoniae. Nat Microbiol. 2016 12 12; 2:16237. PMID: 27941863.
    Citations: 27     Fields:    Translation:Cells
  29. Cho H, Wivagg CN, Kapoor M, Barry Z, Rohs PDA, Suh H, Marto JA, Garner EC, Bernhardt TG. Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously. Nat Microbiol. 2016 Sep 19; 1:16172. PMID: 27643381.
    Citations: 136     Fields:    
  30. Meeske AJ, Riley EP, Robins WP, Uehara T, Mekalanos JJ, Kahne D, Walker S, Kruse AC, Bernhardt TG, Rudner DZ. SEDS proteins are a widespread family of bacterial cell wall polymerases. Nature. 2016 09 29; 537(7622):634-638. PMID: 27525505.
    Citations: 199     Fields:    Translation:Cells
  31. Tsui HC, Zheng JJ, Magallon AN, Ryan JD, Yunck R, Rued BE, Bernhardt TG, Winkler ME. Suppression of a deletion mutation in the gene encoding essential PBP2b reveals a new lytic transglycosylase involved in peripheral peptidoglycan synthesis in Streptococcus pneumoniae D39. Mol Microbiol. 2016 06; 100(6):1039-65. PMID: 26933838; PMCID: PMC5063045.
    Citations: 37     Fields:    Translation:Cells
  32. Markovski M, Bohrhunter JL, Lupoli TJ, Uehara T, Walker S, Kahne DE, Bernhardt TG. Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4788-93. PMID: 27071112; PMCID: PMC4855605.
    Citations: 18     Fields:    Translation:Cells
  33. Meeske AJ, Rodrigues CD, Brady J, Lim HC, Bernhardt TG, Rudner DZ. High-Throughput Genetic Screens Identify a Large and Diverse Collection of New Sporulation Genes in Bacillus subtilis. PLoS Biol. 2016 Jan; 14(1):e1002341. PMID: 26735940.
    Citations: 47     Fields:    Translation:Cells
  34. Yunck R, Cho H, Bernhardt TG. Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria. Mol Microbiol. 2016 Feb; 99(4):700-18. PMID: 26507882; PMCID: PMC4752859.
    Citations: 41     Fields:    Translation:Cells
  35. Yakhnina AA, McManus HR, Bernhardt TG. The cell wall amidase AmiB is essential for Pseudomonas aeruginosa cell division, drug resistance and viability. Mol Microbiol. 2015 Sep; 97(5):957-73. PMID: 26032134; PMCID: PMC4646093.
    Citations: 22     Fields:    Translation:Cells
  36. Meeske AJ, Sham LT, Kimsey H, Koo BM, Gross CA, Bernhardt TG, Rudner DZ. MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6437-42. PMID: 25918422; PMCID: PMC4443310.
    Citations: 84     Fields:    Translation:Cells
  37. Tsang MJ, Bernhardt TG. Guiding divisome assembly and controlling its activity. Curr Opin Microbiol. 2015 Apr; 24:60-5. PMID: 25636132; PMCID: PMC4380671.
    Citations: 23     Fields:    Translation:Cells
  38. Tsang MJ, Bernhardt TG. A role for the FtsQLB complex in cytokinetic ring activation revealed by an ftsL allele that accelerates division. Mol Microbiol. 2015 Mar; 95(6):925-44. PMID: 25496050; PMCID: PMC4414402.
    Citations: 61     Fields:    Translation:Cells
  39. Cho H, Uehara T, Bernhardt TG. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. 2014 Dec 04; 159(6):1300-11. PMID: 25480295.
    Citations: 216     Fields:    Translation:Cells
  40. Sham LT, Butler EK, Lebar MD, Kahne D, Bernhardt TG, Ruiz N. Bacterial cell wall. MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis. Science. 2014 Jul 11; 345(6193):220-2. PMID: 25013077.
    Citations: 132     Fields:    Translation:Cells
  41. Paradis-Bleau C, Kritikos G, Orlova K, Typas A, Bernhardt TG. A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism. PLoS Genet. 2014 Jan; 10(1):e1004056. PMID: 24391520.
    Citations: 47     Fields:    Translation:Cells
  42. Lupoli TJ, Lebar MD, Markovski M, Bernhardt T, Kahne D, Walker S. Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc. 2014 Jan 08; 136(1):52-5. PMID: 24341982.
    Citations: 37     Fields:    Translation:Cells
  43. Bernhardt TG, Vollmer W. Mechanisms of bacterial morphogenesis and their subversion by phages. Curr Opin Microbiol. 2013 Dec; 16(6):728-30. PMID: 24183843.
    Citations:    Fields:    Translation:Cells
  44. Meisner J, Montero Llopis P, Sham LT, Garner E, Bernhardt TG, Rudner DZ. FtsEX is required for CwlO peptidoglycan hydrolase activity during cell wall elongation in Bacillus subtilis. Mol Microbiol. 2013 Sep; 89(6):1069-83. PMID: 23855774.
    Citations: 73     Fields:    Translation:Cells
  45. Peters NT, Morlot C, Yang DC, Uehara T, Vernet T, Bernhardt TG. Structure-function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site. Mol Microbiol. 2013 Aug; 89(4):690-701. PMID: 23796240.
    Citations: 30     Fields:    Translation:Cells
  46. Cho H, Bernhardt TG. Identification of the SlmA active site responsible for blocking bacterial cytokinetic ring assembly over the chromosome. PLoS Genet. 2013; 9(2):e1003304. PMID: 23459366.
    Citations: 24     Fields:    Translation:Cells
  47. Yang DC, Tan K, Joachimiak A, Bernhardt TG. A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division. Mol Microbiol. 2012 Aug; 85(4):768-81. PMID: 22715947.
    Citations: 51     Fields:    Translation:Cells
  48. Uehara T, Bernhardt TG. More than just lysins: peptidoglycan hydrolases tailor the cell wall. Curr Opin Microbiol. 2011 Dec; 14(6):698-703. PMID: 22055466.
    Citations: 57     Fields:    Translation:Cells
  49. Yang DC, Peters NT, Parzych KR, Uehara T, Markovski M, Bernhardt TG. An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring. Proc Natl Acad Sci U S A. 2011 Nov 08; 108(45):E1052-60. PMID: 22006326.
    Citations: 106     Fields:    Translation:Cells
  50. Dinh T, Bernhardt TG. Using superfolder green fluorescent protein for periplasmic protein localization studies. J Bacteriol. 2011 Sep; 193(18):4984-7. PMID: 21764912.
    Citations: 50     Fields:    Translation:Cells
  51. Peters NT, Dinh T, Bernhardt TG. A fail-safe mechanism in the septal ring assembly pathway generated by the sequential recruitment of cell separation amidases and their activators. J Bacteriol. 2011 Sep; 193(18):4973-83. PMID: 21764913.
    Citations: 68     Fields:    Translation:Cells
  52. Cho H, McManus HR, Dove SL, Bernhardt TG. Nucleoid occlusion factor SlmA is a DNA-activated FtsZ polymerization antagonist. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3773-8. PMID: 21321206.
    Citations: 88     Fields:    Translation:Cells
  53. Hale CA, Shiomi D, Liu B, Bernhardt TG, Margolin W, Niki H, de Boer PA. Identification of Escherichia coli ZapC (YcbW) as a component of the division apparatus that binds and bundles FtsZ polymers. J Bacteriol. 2011 Mar; 193(6):1393-404. PMID: 21216997.
    Citations: 53     Fields:    Translation:Cells
  54. Paradis-Bleau C, Markovski M, Uehara T, Lupoli TJ, Walker S, Kahne DE, Bernhardt TG. Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases. Cell. 2010 Dec 23; 143(7):1110-20. PMID: 21183074.
    Citations: 157     Fields:    Translation:Cells
  55. Uehara T, Parzych KR, Dinh T, Bernhardt TG. Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis. EMBO J. 2010 Apr 21; 29(8):1412-22. PMID: 20300061.
    Citations: 151     Fields:    Translation:Cells
  56. Morlot C, Uehara T, Marquis KA, Bernhardt TG, Rudner DZ. A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis. Genes Dev. 2010 Feb 15; 24(4):411-22. PMID: 20159959.
    Citations: 55     Fields:    Translation:Cells
  57. Gerding MA, Liu B, Bendezú FO, Hale CA, Bernhardt TG, de Boer PA. Self-enhanced accumulation of FtsN at Division Sites and Roles for Other Proteins with a SPOR domain (DamX, DedD, and RlpA) in Escherichia coli cell constriction. J Bacteriol. 2009 Dec; 191(24):7383-401. PMID: 19684127.
    Citations: 99     Fields:    Translation:Cells
  58. Uehara T, Dinh T, Bernhardt TG. LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli. J Bacteriol. 2009 Aug; 191(16):5094-107. PMID: 19525345.
    Citations: 111     Fields:    Translation:Cells
  59. Bendezú FO, Hale CA, Bernhardt TG, de Boer PA. RodZ (YfgA) is required for proper assembly of the MreB actin cytoskeleton and cell shape in E. coli. EMBO J. 2009 Feb 04; 28(3):193-204. PMID: 19078962.
    Citations: 163     Fields:    Translation:Cells
  60. Zheng Y, Struck DK, Bernhardt TG, Young R. Genetic analysis of MraY inhibition by the phiX174 protein E. Genetics. 2008 Nov; 180(3):1459-66. PMID: 18791230; PMCID: PMC2581948.
    Citations: 11     Fields:    Translation:Cells
  61. Bernhardt TG, de Boer PA. SlmA, a nucleoid-associated, FtsZ binding protein required for blocking septal ring assembly over Chromosomes in E. coli. Mol Cell. 2005 May 27; 18(5):555-64. PMID: 15916962; PMCID: PMC4428309.
    Citations: 258     Fields:    Translation:Cells
  62. Bernhardt TG, de Boer PA. Screening for synthetic lethal mutants in Escherichia coli and identification of EnvC (YibP) as a periplasmic septal ring factor with murein hydrolase activity. Mol Microbiol. 2004 Jun; 52(5):1255-69. PMID: 15165230; PMCID: PMC4428336.
    Citations: 124     Fields:    Translation:Cells
  63. Bernhardt TG, de Boer PA. The Escherichia coli amidase AmiC is a periplasmic septal ring component exported via the twin-arginine transport pathway. Mol Microbiol. 2003 Jun; 48(5):1171-82. PMID: 12787347; PMCID: PMC4428285.
    Citations: 171     Fields:    Translation:Cells
  64. Bernhardt TG, Wang IN, Struck DK, Young R. Breaking free: "protein antibiotics" and phage lysis. Res Microbiol. 2002 Oct; 153(8):493-501. PMID: 12437210.
    Citations: 39     Fields:    Translation:Cells
  65. Bernhardt TG, Roof WD, Young R. The Escherichia coli FKBP-type PPIase SlyD is required for the stabilization of the E lysis protein of bacteriophage phi X174. Mol Microbiol. 2002 Jul; 45(1):99-108. PMID: 12100551.
    Citations: 22     Fields:    Translation:Cells
  66. Bernhardt TG, Wang IN, Struck DK, Young R. A protein antibiotic in the phage Qbeta virion: diversity in lysis targets. Science. 2001 Jun 22; 292(5525):2326-9. PMID: 11423662.
    Citations: 51     Fields:    Translation:Cells
  67. Bernhardt TG, Struck DK, Young R. The lysis protein E of phi X174 is a specific inhibitor of the MraY-catalyzed step in peptidoglycan synthesis. J Biol Chem. 2001 Mar 02; 276(9):6093-7. PMID: 11078734.
    Citations: 42     Fields:    Translation:Cells
  68. Bernhardt TG, Roof WD, Young R. Genetic evidence that the bacteriophage phi X174 lysis protein inhibits cell wall synthesis. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4297-302. PMID: 10760296; PMCID: PMC18234.
    Citations: 52     Fields:    Translation:Cells
  69. Shi X, Bernhardt TG, Wang SM, Gershon PD. The surface region of the bifunctional vaccinia RNA modifying protein VP39 that interfaces with Poly(A) polymerase is remote from the RNA binding cleft used for its mRNA 5' cap methylation function. J Biol Chem. 1997 Sep 12; 272(37):23292-302. PMID: 9287339.
    Citations: 6     Fields:    Translation:Cells
  70. Doyle KM, Cluette-Brown JE, Dube DM, Bernhardt TG, Morse CR, Laposata M. Fatty acid ethyl esters in the blood as markers for ethanol intake. JAMA. 1996 Oct 09; 276(14):1152-6. PMID: 8827968.
    Citations: 16     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  71. Bernhardt TG, Cannistraro PA, Bird DA, Doyle KM, Laposata M. Purification of fatty acid ethyl esters by solid-phase extraction and high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1996 Jan 26; 675(2):189-96. PMID: 8852705.
    Citations: 5     Fields:    Translation:Humans
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