Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

profileHelen Alice Shih, M.D.

TitleAssociate Professor of Radiation Oncology
InstitutionMassachusetts General Hospital
DepartmentRadiation Oncology
AddressMassachusetts General Hospital
Radiation Oncology
100 Blossom Street
Boston MA 02114
Phone617/724-9627
Fax617/724-9532
vCardDownload vCard (login for email)

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01EB019959     (ZHU, XUPING)Apr 8, 2015 - Mar 31, 2019
NIH/NIBIB
Dynamic PET-DECT for Proton Treatment Verification and Response Assessment
Role: Principal Investigator

U19CA021239     (HONG, THEODORE S)Apr 1, 1997 - Aug 31, 2019
NIH/NCI
Improving the Clinical Effectiveness and Understanding of the Biophysical Basis
Role: Co-Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Sanford NN, Yeap BY, Larvie M, Daartz J, Munzenrider JE, Liebsch NJ, Fullerton B, Pan E, Loeffler JS, Shih HA. Prospective, Randomized Study of Radiation Dose Escalation With Combined Proton-Photon Therapy for Benign Meningiomas. Int J Radiat Oncol Biol Phys. 2017 Jul 12. PMID: 28865924.
    View in: PubMed
  2. Kim D, Niemierko A, Hwang WL, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Oh KS, Loeffler JS, Shih HA. Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas. J Neurosurg. 2017 Jun 16; 1-10. PMID: 28621619.
    View in: PubMed
  3. Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP. Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA). JAMA Oncol. 2017 Jun 01; 3(6):827-831. PMID: 27892978.
    View in: PubMed
  4. Kirkpatrick JP, Laack NN, Shih HA, Gondi V. Management of GBM: a problem of local recurrence. J Neurooncol. 2017 Apr 04. PMID: 28378194.
    View in: PubMed
  5. Grosshans DR, Mohan R, Gondi V, Shih HA, Mahajan A, Brown PD. The role of image-guided intensity modulated proton therapy in glioma. Neuro Oncol. 2017 04 01; 19(suppl_2):ii30-ii37. PMID: 28380636.
    View in: PubMed
  6. Sperduto PW, Jiang W, Brown PD, Braunstein S, Sneed P, Wattson DA, Shih HA, Bangdiwala A, Shanley R, Lockney NA, Beal K, Lou E, Amatruda T, Sperduto WA, Kirkpatrick JP, Yeh N, Gaspar LE, Molitoris JK, Masucci L, Roberge D, Yu J, Chiang V, Mehta M. The Prognostic Value of BRAF, C-KIT, and NRAS Mutations in Melanoma Patients With Brain Metastases. Int J Radiat Oncol Biol Phys. 2017 Aug 01; 98(5):1069-1077. PMID: 28721890.
    View in: PubMed
  7. Chang S, Zhang P, Cairncross JG, Gilbert MR, Bahary JP, Dolinskas CA, Chakravarti A, Aldape KD, Bell EH, Schiff D, Jaeckle K, Brown PD, Barger GR, Werner-Wasik M, Shih H, Brachman D, Penas-Prado M, Robins HI, Belanger K, Schultz C, Hunter G, Mehta M. Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813. Neuro Oncol. 2017 02 01; 19(2):252-258. PMID: 27994066.
    View in: PubMed
  8. Roongpiboonsopit D, Kuijf HJ, Charidimou A, Xiong L, Vashkevich A, Martinez-Ramirez S, Shih HA, Gill CM, Viswanathan A, Dietrich J. Evolution of cerebral microbleeds after cranial irradiation in medulloblastoma patients. Neurology. 2017 Feb 21; 88(8):789-796. PMID: 28122904.
    View in: PubMed
  9. Mouw KW, Yeap BY, Caruso P, Fay A, Misra M, Sethi RV, MacDonald SM, Chen YL, Tarbell NJ, Yock TI, Freitag SK, Munzenrider JE, Grabowski E, Katz M, Kuhlthau K, DeCastro D, Heidary G, Ciralsky J, Mukai S, Shih HA. Analysis of patient outcomes following proton radiation therapy for retinoblastoma. Adv Radiat Oncol. 2017 Jan-Mar; 2(1):44-52. PMID: 28607957.
    View in: PubMed
  10. Singh AD, Dupps WJ, Biscotti CV, Suh JH, Lathrop KL, Nairn JP, Shih H. Limbal Stem Cell Preservation During Proton Beam Irradiation for Diffuse Iris Melanoma. Cornea. 2017 Jan; 36(1):119-122. PMID: 27755196.
    View in: PubMed
  11. Geng C, Daartz J, Lam-Tin-Cheung K, Bussiere M, Shih HA, Paganetti H, Schuemann J. Limitations of analytical dose calculations for small field proton radiosurgery. Phys Med Biol. 2017 Jan 07; 62(1):246-257. PMID: 27991438.
    View in: PubMed
  12. Kirkpatrick JP, Laack NN, Soltys SG, Halasz LM, Breneman JC, Shih HA. Brain Metastases From Melanoma: Therapy at the Crossroads. Int J Radiat Oncol Biol Phys. 2016 Nov 15; 96(4):713-716. PMID: 27788943.
    View in: PubMed
  13. Wilkinson B, Morgan H, Gondi V, Larson GL, Hartsell WF, Laramore GE, Halasz LM, Vargas C, Keole SR, Grosshans DR, Shih HA, Mehta MP. Low Levels of Acute Toxicity Associated With Proton Therapy for Low-Grade Glioma: A Proton Collaborative Group Study. Int J Radiat Oncol Biol Phys. 2016 Oct 01; 96(2S):E135. PMID: 27673869.
    View in: PubMed
  14. Jafari-Khouzani K, Loebel F, Bogner W, Rapalino O, Gonzalez GR, Gerstner E, Chi AS, Batchelor TT, Rosen BR, Unkelbach J, Shih HA, Cahill DP, Andronesi OC. Volumetric relationship between 2-hydroxyglutarate and FLAIR hyperintensity has potential implications for radiotherapy planning of mutant IDH glioma patients. Neuro Oncol. 2016 Nov; 18(11):1569-1578. PMID: 27382115.
    View in: PubMed
  15. Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP. The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases. Int J Radiat Oncol Biol Phys. 2016 Oct 01; 96(2):406-413. PMID: 27598807.
    View in: PubMed
  16. Cabrera AR, Kirkpatrick JP, Fiveash JB, Shih HA, Koay EJ, Lutz S, Petit J, Chao ST, Brown PD, Vogelbaum M, Reardon DA, Chakravarti A, Wen PY, Chang E. Radiation therapy for glioblastoma: Executive summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline. Pract Radiat Oncol. 2016 Jul-Aug; 6(4):217-25. PMID: 27211230.
    View in: PubMed
  17. Shih HA. Central Nervous System: Progress of Today and a Preview of Tomorrow. Int J Radiat Oncol Biol Phys. 2016 Mar 01; 94(3):425-7. PMID: 26867869.
    View in: PubMed
  18. Warren LE, Kim MB, Martin NE, Shih HA. Analysis of After-Hours Patient Telephone Calls in Two Academic Radiation Oncology Departments: An Opportunity for Improvement in Patient Safety and Quality of Care. J Oncol Pract. 2016 Apr; 12(4):e487-94. PMID: 26907449.
    View in: PubMed
  19. Unkelbach J, Bussière MR, Chapman PH, Loeffler JS, Shih HA. Spatiotemporal Fractionation Schemes for Irradiating Large Cerebral Arteriovenous Malformations. Int J Radiat Oncol Biol Phys. 2016 Jul 01; 95(3):1067-1074. PMID: 27113566; PMCID: PMC4909567 [Available on 07/01/17].
  20. Hrbacek J, Mishra KK, Kacperek A, Dendale R, Nauraye C, Auger M, Herault J, Daftari IK, Trofimov AV, Shih HA, Chen YL, Denker A, Heufelder J, Horwacik T, Swakon J, Hoehr C, Duzenli C, Pica A, Goudjil F, Mazal A, Thariat J, Weber DC. Practice Patterns Analysis of Ocular Proton Therapy Centers: The International OPTIC Survey. Int J Radiat Oncol Biol Phys. 2016 May 01; 95(1):336-43. PMID: 27084651.
    View in: PubMed
  21. Patel AV, Miller JB, Nath R, Shih HA, Yoon MK, Freitag SK, Papaliodis G, Chen TC, Eliott D, Kim IK. Unilateral Eye Findings: A Rare Herald of Acute Leukemia. Ocul Oncol Pathol. 2016 Apr; 2(3):166-70. PMID: 27239459; PMCID: PMC4881258.
  22. Sherman JC, Colvin MK, Mancuso SM, Batchelor TT, Oh KS, Loeffler JS, Yeap BY, Shih HA. Neurocognitive effects of proton radiation therapy in adults with low-grade glioma. J Neurooncol. 2016 Jan; 126(1):157-64. PMID: 26498439.
    View in: PubMed
  23. Gainor JF, Chi AS, Logan J, Hu R, Oh KS, Brastianos PK, Shih HA, Shaw AT. Alectinib Dose Escalation Reinduces Central Nervous System Responses in Patients with Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer Relapsing on Standard Dose Alectinib. J Thorac Oncol. 2016 Feb; 11(2):256-60. PMID: 26845119; PMCID: PMC4743545 [Available on 02/01/17].
  24. Hwang WL, Marciscano AE, Niemierko A, Kim DW, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Loeffler JS, Oh KS, Shih HA, Larvie M. Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade. Neuro Oncol. 2016 Jun; 18(6):863-72. PMID: 26597949; PMCID: PMC4864259 [Available on 06/01/17].
  25. Patel AV, Lane AM, Morrison MA, Trofimov AV, Shih HA, Gragoudas ES, Kim IK. Visual Outcomes after Proton Beam Irradiation for Choroidal Melanomas Involving the Fovea. Ophthalmology. 2016 Feb; 123(2):369-77. PMID: 26545316.
    View in: PubMed
  26. Wu WW, Bi WL, Kang YJ, Ramkissoon SH, Prasad S, Shih HA, Reardon DA, Dunn IF. Adult Atypical Teratoid/Rhabdoid Tumors. World Neurosurg. 2016 Jan; 85:197-204. PMID: 26344637.
    View in: PubMed
  27. Marciscano AE, Stemmer-Rachamimov AO, Niemierko A, Larvie M, Curry WT, Barker FG, Martuza RL, McGuone D, Oh KS, Loeffler JS, Shih HA. Benign meningiomas (WHO Grade I) with atypical histological features: correlation of histopathological features with clinical outcomes. J Neurosurg. 2016 Jan; 124(1):106-14. PMID: 26274991.
    View in: PubMed
  28. Soltys SG, Kirkpatrick JP, Laack NN, Kavanagh BD, Breneman JC, Shih HA. Is Less, More? The Evolving Role of Radiation Therapy for Brain Metastases. Int J Radiat Oncol Biol Phys. 2015 Aug 01; 92(5):963-966. PMID: 26194672.
    View in: PubMed
  29. Wattson DA, Sullivan RJ, Niemierko A, Merritt RM, Lawrence DP, Oh KS, Flaherty KT, Shih HA. Survival patterns following brain metastases for patients with melanoma in the MAP-kinase inhibitor era. J Neurooncol. 2015 May; 123(1):75-84. PMID: 25864098.
    View in: PubMed
  30. Grogg K, Alpert NM, Zhu X, Min CH, Testa M, Winey B, Normandin MD, Shih HA, Paganetti H, Bortfeld T, El Fakhri G. Mapping (15)O production rate for proton therapy verification. Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):453-9. PMID: 25817530; PMCID: PMC4431894.
  31. Yamasaki A, Sedaghat AR, Lin GC, Curry WT, Shih HA, Gray ST. A Rare Finding of Schwannoma of the Vidian Canal: A Case Report. J Neurol Surg Rep. 2015 Jul; 76(1):e48-51. PMID: 26251809; PMCID: PMC4520991.
  32. Shih HA, Sherman JC, Nachtigall LB, Colvin MK, Fullerton BC, Daartz J, Winrich BK, Batchelor TT, Thornton LT, Mancuso SM, Saums MK, Oh KS, Curry WT, Loeffler JS, Yeap BY. Proton therapy for low-grade gliomas: Results from a prospective trial. Cancer. 2015 May 15; 121(10):1712-9. PMID: 25585890.
    View in: PubMed
  33. Cheney MD, Chen YL, Lim R, Winrich BK, Grosu AL, Trofimov AV, Depauw N, Shih HA, Schwab JH, Hornicek FJ, DeLaney TF. [18F]-Fluoromisonidazole positron emission tomography/computed tomography visualization of tumor hypoxia in patients with chordoma of the mobile and sacrococcygeal spine. Int J Radiat Oncol Biol Phys. 2014 Dec 01; 90(5):1030-6. PMID: 25539367; PMCID: PMC4280072.
  34. Kamran SC, Collier JM, Lane AM, Kim I, Niemierko A, Chen YL, MacDonald SM, Munzenrider JE, Gragoudas E, Shih HA. Outcomes of proton therapy for the treatment of uveal metastases. Int J Radiat Oncol Biol Phys. 2014 Dec 01; 90(5):1044-50. PMID: 25442038.
    View in: PubMed
  35. Mouw KW, Sethi RV, Yeap BY, MacDonald SM, Chen YL, Tarbell NJ, Yock TI, Munzenrider JE, Adams J, Grabowski E, Mukai S, Shih HA. Proton radiation therapy for the treatment of retinoblastoma. Int J Radiat Oncol Biol Phys. 2014 Nov 15; 90(4):863-9. PMID: 25227498; PMCID: PMC4253018.
  36. Wattson DA, Tanguturi SK, Spiegel DY, Niemierko A, Biller BM, Nachtigall LB, Bussière MR, Swearingen B, Chapman PH, Loeffler JS, Shih HA. Outcomes of proton therapy for patients with functional pituitary adenomas. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):532-9. PMID: 25194666.
    View in: PubMed
  37. Mak KS, Gainor JF, Niemierko A, Oh KS, Willers H, Choi NC, Loeffler JS, Sequist LV, Shaw AT, Shih HA. Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non-small cell lung cancer treated with radiotherapy for brain metastases. Neuro Oncol. 2015 Feb; 17(2):296-302. PMID: 25053852; PMCID: PMC4288518.
  38. Trofimov A, Carpenter K, Shih HA. SU-E-CAMPUS-T-01: Analysis of the Precision of Patient Set-Up, and Fidelity of the Delivered Dose Distribution in Proton Therapy of Ocular Tumors. Med Phys. 2014 Jun; 41(6):383. PMID: 28036951.
    View in: PubMed
  39. Jones PS, Aghi MK, Muzikansky A, Shih HA, Barker FG, Curry WT. Outcomes and patterns of care in adult skull base chordomas from the Surveillance, Epidemiology, and End Results (SEER) database. J Clin Neurosci. 2014 Sep; 21(9):1490-6. PMID: 24852903.
    View in: PubMed
  40. Niu NN, Niemierko A, Larvie M, Curtin H, Loeffler JS, McKenna MJ, Shih HA. Pretreatment growth rate predicts radiation response in vestibular schwannomas. Int J Radiat Oncol Biol Phys. 2014 May 01; 89(1):113-9. PMID: 24725695.
    View in: PubMed
  41. Jones PS, Aghi MK, Muzikansky A, Shih HA, Barker FG, Curry WT. Outcomes and patterns of care in adult skull base chondrosarcomas from the SEER database. J Clin Neurosci. 2014 Sep; 21(9):1497-502. PMID: 24792724.
    View in: PubMed
  42. Hattangadi-Gluth JA, Chapman PH, Kim D, Niemierko A, Bussière MR, Stringham A, Daartz J, Ogilvy C, Loeffler JS, Shih HA. Single-fraction proton beam stereotactic radiosurgery for cerebral arteriovenous malformations. Int J Radiat Oncol Biol Phys. 2014 Jun 01; 89(2):338-46. PMID: 24726288.
    View in: PubMed
  43. Pier DB, Nunes FP, Plotkin SR, Stemmer-Rachamimov AO, Kim JC, Shih HA, Brastianos P, Lin AE. Turner syndrome and meningioma: support for a possible increased risk of neoplasia in Turner syndrome. Eur J Med Genet. 2014 May-Jun; 57(6):269-74. PMID: 24675142.
    View in: PubMed
  44. Winey B, Shih HA, Sahoo N, Lee A, Vapiwala N, Both S. Core physics competencies for proton therapy training of radiation oncology and medical physics residents and fellows. Int J Radiat Oncol Biol Phys. 2014 Mar 15; 88(4):971-2. PMID: 24606858.
    View in: PubMed
  45. Snuderl M, Triscott J, Northcott PA, Shih HA, Kong E, Robinson H, Dunn SE, Iafrate AJ, Yip S. Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma. J Clin Oncol. 2015 Feb 20; 33(6):e27-31. PMID: 24616312; PMCID: PMC4517370.
  46. Unkelbach J, Menze BH, Konukoglu E, Dittmann F, Ayache N, Shih HA. Radiotherapy planning for glioblastoma based on a tumor growth model: implications for spatial dose redistribution. Phys Med Biol. 2014 Feb 07; 59(3):771-89. PMID: 24440905.
    View in: PubMed
  47. Unkelbach J, Menze BH, Konukoglu E, Dittmann F, Le M, Ayache N, Shih HA. Radiotherapy planning for glioblastoma based on a tumor growth model: improving target volume delineation. Phys Med Biol. 2014 Feb 07; 59(3):747-70. PMID: 24440875.
    View in: PubMed
  48. Sethi RV, Shih HA, Yeap BY, Mouw KW, Petersen R, Kim DY, Munzenrider JE, Grabowski E, Rodriguez-Galindo C, Yock TI, Tarbell NJ, Marcus KJ, Mukai S, MacDonald SM. Second nonocular tumors among survivors of retinoblastoma treated with contemporary photon and proton radiotherapy. Cancer. 2014 Jan 01; 120(1):126-33. PMID: 24122173; PMCID: PMC3959122.
  49. Aizer AA, Ancukiewicz M, Nguyen PL, Shih HA, Loeffler JS, Oh KS. Underutilization of radiation therapy in patients with glioblastoma: predictive factors and outcomes. Cancer. 2014 Jan 15; 120(2):238-43. PMID: 24122361.
    View in: PubMed
  50. Grogg K, Zhu X, Min CH, Winey B, Bortfeld T, Paganetti H, Shih HA, El Fakhri G. Feasibility of Using Distal Endpoints for In-room PET Range Verification of Proton Therapy. IEEE Trans Nucl Sci. 2013 Oct; 60(5):3290-3297. PMID: 24464031.
    View in: PubMed
  51. Aizer AA, Ancukiewicz M, Nguyen PL, Macdonald SM, Yock TI, Tarbell NJ, Shih HA, Loeffler JS, Oh KS. Natural history and role of radiation in patients with supratentorial and infratentorial WHO grade II ependymomas: results from a population-based study. J Neurooncol. 2013 Dec; 115(3):411-9. PMID: 24057324.
    View in: PubMed
  52. Sperduto PW, Kased N, Roberge D, Chao ST, Shanley R, Luo X, Sneed PK, Suh J, Weil RJ, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer. J Neurooncol. 2013 May; 112(3):467-72. PMID: 23462853.
    View in: PubMed
  53. Min CH, Zhu X, Winey BA, Grogg K, Testa M, El Fakhri G, Bortfeld TR, Paganetti H, Shih HA. Clinical application of in-room positron emission tomography for in vivo treatment monitoring in proton radiation therapy. Int J Radiat Oncol Biol Phys. 2013 May 01; 86(1):183-9. PMID: 23391817; PMCID: PMC3640852.
  54. Shih HA. Oncology scan--high-grade gliomas. Int J Radiat Oncol Biol Phys. 2013 Feb 01; 85(2):283-5. PMID: 23312262.
    View in: PubMed
  55. Sperduto PW, Sneed PK, Roberge D, Shanley R, Luo X, Luo X, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Knisely JP, Lin N, Mehta M. In regard to Yamamoto et al. Int J Radiat Oncol Biol Phys. 2012 Nov 15; 84(4):875-6; discussion 876-7. PMID: 23078894.
    View in: PubMed
  56. Verburg JM, Shih HA, Seco J. Simulation of prompt gamma-ray emission during proton radiotherapy. Phys Med Biol. 2012 Sep 07; 57(17):5459-72. PMID: 22864267.
    View in: PubMed
  57. Dennis ER, Bussiere MR, Niemierko A, Lu MW, Fullerton BC, Loeffler JS, Shih HA. A comparison of critical structure dose and toxicity risks in patients with low grade gliomas treated with IMRT versus proton radiation therapy. Technol Cancer Res Treat. 2013 Feb; 12(1):1-9. PMID: 22775339.
    View in: PubMed
  58. Arvold ND, Niemierko A, Broussard GP, Adams J, Fullerton B, Loeffler JS, Shih HA. Projected second tumor risk and dose to neurocognitive structures after proton versus photon radiotherapy for benign meningioma. Int J Radiat Oncol Biol Phys. 2012 Jul 15; 83(4):e495-500. PMID: 22285662.
    View in: PubMed
  59. Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Summary report on the graded prognostic assessment: an accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases. J Clin Oncol. 2012 Feb 01; 30(4):419-25. PMID: 22203767; PMCID: PMC3269967.
  60. Hattangadi JA, Chapman PH, Bussière MR, Niemierko A, Ogilvy CS, Rowell A, Daartz J, Loeffler JS, Shih HA. Planned two-fraction proton beam stereotactic radiosurgery for high-risk inoperable cerebral arteriovenous malformations. Int J Radiat Oncol Biol Phys. 2012 Jun 01; 83(2):533-41. PMID: 22099050.
    View in: PubMed
  61. Sperduto PW, Kased N, Roberge D, Shanley R, Chao ST, Bhatt AK, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE. The effect of tumor subtype on survival and the graded prognostic assessment (GPA) for patients with breast cancer and brain metastases. J Clin Oncol. 2011 Sep 20; 29(27_suppl):238. PMID: 27958084.
    View in: PubMed
  62. Winkfield KM, Niemierko A, Bussiere MR, Crowley EM, Napolitano BN, Beaudette KP, Loeffler JS, Shih HA. Modeling intracranial second tumor risk and estimates of clinical toxicity with various radiation therapy techniques for patients with pituitary adenoma. Technol Cancer Res Treat. 2011 Jun; 10(3):243-51. PMID: 21517130.
    View in: PubMed
  63. Son CH, Jimenez R, Niemierko A, Loeffler JS, Oh KS, Shih HA. Outcomes after whole brain reirradiation in patients with brain metastases. Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):e167-72. PMID: 21620583.
    View in: PubMed
  64. Loeffler JS, Shih HA. Radiation therapy in the management of pituitary adenomas. J Clin Endocrinol Metab. 2011 Jul; 96(7):1992-2003. PMID: 21525155.
    View in: PubMed
  65. Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases. Int J Radiat Oncol Biol Phys. 2012 Apr 01; 82(5):2111-7. PMID: 21497451; PMCID: PMC3172400.
  66. Craft DL, Hong TS, Shih HA, Bortfeld TR. Improved planning time and plan quality through multicriteria optimization for intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2012 Jan 01; 82(1):e83-90. PMID: 21300448; PMCID: PMC3202037.
  67. Halasz LM, Bussière MR, Dennis ER, Niemierko A, Chapman PH, Loeffler JS, Shih HA. Proton stereotactic radiosurgery for the treatment of benign meningiomas. Int J Radiat Oncol Biol Phys. 2011 Dec 01; 81(5):1428-35. PMID: 20934263.
    View in: PubMed
  68. Knopf AC, Parodi K, Paganetti H, Bortfeld T, Daartz J, Engelsman M, Liebsch N, Shih H. Accuracy of proton beam range verification using post-treatment positron emission tomography/computed tomography as function of treatment site. Int J Radiat Oncol Biol Phys. 2011 Jan 01; 79(1):297-304. PMID: 20646839.
    View in: PubMed
  69. Sperduto PW, Chao ST, Sneed PK, Luo X, Suh J, Roberge D, Bhatt A, Jensen AW, Brown PD, Shih H, Kirkpatrick J, Schwer A, Gaspar LE, Fiveash JB, Chiang V, Knisely J, Sperduto CM, Mehta M. Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients. Int J Radiat Oncol Biol Phys. 2010 Jul 01; 77(3):655-61. PMID: 19942357.
    View in: PubMed
  70. Knopf A, Parodi K, Bortfeld T, Shih HA, Paganetti H. Systematic analysis of biological and physical limitations of proton beam range verification with offline PET/CT scans. Phys Med Biol. 2009 Jul 21; 54(14):4477-95. PMID: 19556685.
    View in: PubMed
  71. Arvold ND, Lessell S, Bussiere M, Beaudette K, Rizzo JF, Loeffler JS, Shih HA. Visual outcome and tumor control after conformal radiotherapy for patients with optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys. 2009 Nov 15; 75(4):1166-72. PMID: 19406585.
    View in: PubMed
  72. Baeten J, Haller J, Shih H, Ntziachristos V. In vivo investigation of breast cancer progression by use of an internal control. Neoplasia. 2009 Mar; 11(3):220-7. PMID: 19242603; PMCID: PMC2647724.
  73. Shih HA, Loeffler JS, Tarbell NJ. Late effects of CNS radiation therapy. Cancer Treat Res. 2009; 150:23-41. PMID: 19834660.
    View in: PubMed
  74. Shih H, Knopf A, Parodi K, Paganetti H, Bortfeld T. PET/CT treatment verification after proton therapy in abdominopelvic tumor sites. 50th Annual Meeting of the American Society for Therapeutic Radiology and Oncology. 2008; 71.
  75. Halasz LM, Bussiere MR, Niemierko A, Chapman PH, Loeffler JS, Shih HA. Outcomes of Patients with Benign Meningiomas treated with Proton Stereotactic Radiosurgery. 50th Annual Meeting of the American Society for Therapeutic Radiology and Oncology. 2008; 71.
  76. Shih HA, Loeffler JS. Radiation therapy in acromegaly. Rev Endocr Metab Disord. 2008 Mar; 9(1):59-65. PMID: 18080837.
    View in: PubMed
  77. Nachtigall LB, Shih HA. Fractionated radiotherapy versus stereotactic radiosurgery for pituitary adenomas. Nat Clin Pract Neurol. 2008 Mar; 4(3):134-5. PMID: 18227826.
    View in: PubMed
  78. Parodi K, Bortfeld T, Enghardt W, Fiedler F, Knopf A, Paganetti H, Pawelke J, Shakirin G, Shih H. PET imaging for treatment verification of ion therapy: Implementation and experience at GSI Darmstadt and MGH Boston. Nucl Instrumen MEthods Phys Research. 2008; 591:282-6.
  79. Helen A. Shih, Jay S. Loeffler. Radiation therapy for pituitary adenomas. Diagnosis and management of pituitary disorders. Editors: Brooke Swearingen & Beverly M. K. Biller. 2008; 321-338.
  80. Arvold N, Lessell S, Rizzo JF, Liebsch NJ, Yock TI, Loeffler JS, Shih HA. Visual outcome and tumor control following conformal radiotherapy for patients with optic nerve sheath meningioma. 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology. 2007.
  81. Winkfield K, Shih HA, Niemierko A, Bussiere MR, Crowley EM, Beaudette KP, Pope CJ, Loeffler JS. Second tumor risk with modern radiotherapy for pituitary adenomas . 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology. 2007.
  82. Craft D, Halabi T, Shih HA, Bortfeld T. An approach for practical multiobjective IMRT treatment planning. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1600-7. PMID: 17920782.
    View in: PubMed
  83. Shih HA, Chapman PH, Bussiere MR, Chen CC, Loeffler JS. Central nervous system tumors: proton & heavy charged particles. Proton and charged particle radiotherapy. 2007.
  84. Parodi K, Paganetti H, Shih HA, Michaud S, Loeffler JS, DeLaney TF, Liebsch NJ, Munzenrider JE, Fischman AJ, Knopf A, Bortfeld T. Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy. Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):920-34. PMID: 17544003; PMCID: PMC2047826.
  85. Chen CC, Hochberg F, Batchelor T, Shih HA, Chakravarti A, Chapman P, Loeffler J. Radiosurgery for primary central nervous system lymphoma (PCNSL). Congress on International Stereotactic Radiosurgery Society (ISRS). 2007.
  86. John K Park, Peter M Black, Helen A Shih. Treatment of meningiomas. UpToDate. 2007.
  87. Evangelos S Gragoudas, Anne Marie Lane, Helen A Shih. Management of intraocular melanoma. UpToDate. 2007.
  88. Elia AE, Shih HA, Loeffler JS. Stereotactic radiation treatment for benign meningiomas. Neurosurg Focus. 2007; 23(4):E5. PMID: 17961042.
    View in: PubMed
  89. Shih HA, Zietman AL. In reply to Drs. Rubin and Hansen. Int J Radiat Oncol Biol Phys. 2006; 66(5):1593.
  90. Shih HA, Parodi K, Paganetti H, Michaud S, Loeffler JS, DeLaney TF, Liebsch NJ, Munzenrider JE, Fischman AJ, Bortfeld T. Clinical feasibility of PET/CT image guidance after proton radiotherapy. Proceedings for the American Society of Therapeutic Radiology and Oncology. 2006; 66(3):S704.
  91. Craft DL, Halabi TF, Shih HA, Bortfeld TR. Approximating convex pareto surfaces in multiobjective radiotherapy planning. Med Phys. 2006 Sep; 33(9):3399-407. PMID: 17022236.
    View in: PubMed
  92. Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V. Normalized transillumination of fluorescent proteins in small animals. Mol Imaging. 2006 Jul; 5(3):153-9. PMID: 16954030.
    View in: PubMed
  93. Shih HA, Windsor SD, Weissleder R, Ntziachristos V . In-vivo characterization of tumors of Her-2/neu mice using fluorescence molecular tomography. Third Annual Symposium of the Dana-Farber/Harvard Cancer Center Program in Breast Cancer. 2006.
  94. Shih HA, Windsor S, Weisseleder R, Ntziachristos V . In vivo characterization of Her-2/neu carcinogenesis in mice using fluorescence molecular tomography. Biomedical Optics Annual Conference. 2006.
  95. Tsai HT, Hong TS, Willins J, Kung JK, Feng JK, Shih HA, Kachnic LA. Dosimetric comparison of dose-painted intensity modulated radiation therapy versus conventional radiation therapy for anal cancer. Annual Gastrointestinal Cancers Symposium. 2006.
  96. Tracy Batchelor, Helen A Shih. Management of high grade gliomas. UpToDate. 2006.
  97. Helen A Shih, Jay S Loeffler. Patient Information: Frequently Asked Questions about Radiation Therapy for Pituitary Adenomas. 2006.
  98. Lawrence D Recht, Helen A Shih. Management of low-grade gliomas. UpToDate. 2006.
  99. Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V. Volumetric tomography of fluorescent proteins through small animals in vivo. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18252-7. PMID: 16344470; PMCID: PMC1317905.
  100. Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R. Mapping of nodal disease in locally advanced prostate cancer: rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy. Int J Radiat Oncol Biol Phys. 2005 Nov 15; 63(4):1262-9. PMID: 16253781.
    View in: PubMed
  101. Ntziachristos V, Turner G, Dunham J, Windsor S, Soubret A, Ripoll J, Shih HA. Planar fluorescence imaging using normalized data. J Biomed Opt. 2005 Nov-Dec; 10(6):064007. PMID: 16409072.
    View in: PubMed
  102. Windsor SD, Shih HA, Ntziachristos V. Simultaneous imaging of protease expression and biodistribution in Her-2/neu mice using dual-wavelength fluorescence molecular tomography. Fourth Annual Meeting of The Society for Molecular Imaging. 2005.
  103. Halabi T, Bortfeld T, Craft D, Wolfgang J, Gierga D, Zietman A, Shih H. Effect of daily shifts of IMRT prostate patients on dose to pelvic nodes. 47th Annual Meeting of the American Association of Physicists in Medicine. 2005.
  104. Shih HA, Betensky RA, Dorfman MV, Louis DN, Loeffler JS, Batchelor TT. Genetic analyses for predictors of radiation response in glioblastoma. Int J Radiat Oncol Biol Phys. 2005 Nov 01; 63(3):704-10. PMID: 15978739.
    View in: PubMed
  105. Windsor SD, Shih HA, Ntziachristos V. In-vivo fluorescence molecular tomography of mammary adenocarcinomas in transgenic mice bearing an activated c-neu oncogene. Era of Hope, Department of Defense, Breast Cancer Research Program. 2005.
  106. Willett CG, Del Castillo CF, Shih HA, Goldberg S, Biggs P, Clark JW, Lauwers G, Ryan DP, Zhu AX, Warshaw AL. Long-term results of intraoperative electron beam irradiation (IOERT) for patients with unresectable pancreatic cancer. Ann Surg. 2005 Feb; 241(2):295-9. PMID: 15650640; PMCID: PMC1356915.
  107. Shih HA, Jiang SB, Aljarrah KM, Doppke KP, Choi NC. Internal target volume determined with expansion margins beyond composite gross tumor volume in three-dimensional conformal radiotherapy for lung cancer. Int J Radiat Oncol Biol Phys. 2004 Oct 01; 60(2):613-22. PMID: 15380599.
    View in: PubMed
  108. Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R. Mapping of nodal disease in locally advanced prostate cancer: rethinking the clinical target volume for pelvic node radiation based on vascular rather than bony anatomy. International Journal of Radiation Oncology*Biology*Physics. 2004; 60(1):S264.
  109. Loeffler JS, Shih HA, Betensky RA, Dorfman MV, Louis DN, Batchelor TT. Genetic determinants of radiation reponse in glioblastoma. International Journal of Radiation Oncology*Biology*Physics. 2004; 60(1):S263.
  110. Kachnic LA, Shih HA, Willett CG. Advances in combined radiation therapy for the management of rectal cancer. Expert Rev Anticancer Ther. 2003 Aug; 3(4):471-83. PMID: 12934659.
    View in: PubMed
  111. Martin AM, Kanetsky PA, Amirimani B, Colligon TA, Athanasiadis G, Shih HA, Gerrero MR, Calzone K, Rebbeck TR, Weber BL. Germline TP53 mutations in breast cancer families with multiple primary cancers: is TP53 a modifier of BRCA1? J Med Genet. 2003 Apr; 40(4):e34. PMID: 12676907; PMCID: PMC1735423.
  112. Shih HA, Hornicek FJ, DeLaney TF, Harmon DC, Suit HD. Fibromatosis: current strategies for treatment. Curr Opin Orthopaed. 2003; 14(6):405-12.
  113. Shih HA, Couch FJ, Nathanson KL, Blackwood MA, Rebbeck TR, Armstrong KA, Calzone K, Stopfer J, Seal S, Stratton MR, Weber BL. BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic. J Clin Oncol. 2002 Feb 15; 20(4):994-9. PMID: 11844822.
    View in: PubMed
  114. Martin AM, Blackwood MA, Antin-Ozerkis D, Shih HA, Calzone K, Colligon TA, Seal S, Collins N, Stratton MR, Weber BL, Nathanson KL. Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breast cancer risk evaluation clinic. J Clin Oncol. 2001 Apr 15; 19(8):2247-53. PMID: 11304778.
    View in: PubMed
  115. Shih HA, Nathanson KL, Seal S, Collins N, Stratton MR, Rebbeck TR, Weber BL. BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers. Clin Cancer Res. 2000 Nov; 6(11):4259-64. PMID: 11106241.
    View in: PubMed
  116. Shih HA, Kao DM, Elenitsas R, Leyden JJ. Livedo reticularis, ulcers, and peripheral gangrene: cutaneous manifestations of primary hyperoxaluria. Arch Dermatol. 2000 Oct; 136(10):1272-4. PMID: 11030785.
    View in: PubMed
  117. Unger MA, Nathanson KL, Calzone K, Antin-Ozerkis D, Shih HA, Martin AM, Lenoir GM, Mazoyer S, Weber BL. Screening for genomic rearrangements in families with breast and ovarian cancer identifies BRCA1 mutations previously missed by conformation-sensitive gel electrophoresis or sequencing. Am J Hum Genet. 2000 Oct; 67(4):841-50. PMID: 10978226; PMCID: PMC1287889.
  118. Meng RD, Shih H, Prabhu NS, George DL, el-Deiry WS. Bypass of abnormal MDM2 inhibition of p53-dependent growth suppression. Clin Cancer Res. 1998 Jan; 4(1):251-9. PMID: 9516979.
    View in: PubMed
  119. Hall WS, Goto-Mandeville R, Shih HA, Shank PR, Braun L. Molecular analysis of episomal human papillomavirus type 16 DNA in a cervical carcinoma cell line. Virus Res. 1997 Oct; 51(2):183-95. PMID: 9498616.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Shih's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
_
Co-Authors Expand Description
_
Similar People Expand Description
_
Same Department Expand Description
Physical Neighbors Expand Description
_