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profileDavid Crittenden Hooper, M.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Infectious Disease
55 Fruit St
Boston MA 02114
Phone617/726-3812
Fax617/726-7416
vCardDownload vCard (login for email)

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
P01AI083214     (GILMORE, MICHAEL S)Sep 1, 2009 - Aug 31, 2021
NIH/NIAID
Harvard-wide Program on Antibiotic Resistance
Role: Co-Principal Investigator
R01AI057576     (HOOPER, DAVID C)Jan 1, 2004 - Jun 30, 2019
NIH/NIAID
Plasmid-mediated Quinolone Resistance
Role: Principal Investigator
R37AI023988     (HOOPER, DAVID C)Sep 1, 1986 - Mar 31, 2018
NIH/NIAID
Quinolone and multidrug resistance in Staphylococcus aureus
Role: Principal Investigator
R01AI023988     (HOOPER, DAVID C)Sep 1, 1986 - Mar 31, 2008
NIH/NIAID
Quinolone Resistance Mechanisms in Staphylococcus aureus
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Matano LM, Morris HG, Hesser AR, Martin SES, Lee W, Owens TW, Laney E, Nakaminami H, Hooper D, Meredith TC, Walker S. Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site. J Am Chem Soc. 2017 Aug 09; 139(31):10597-10600. PMID: 28727445.
    View in: PubMed
  2. Truong-Bolduc QC, Wang Y, Chen C, Hooper DC. Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. Antimicrob Agents Chemother. 2017 Aug; 61(8). PMID: 28584148.
    View in: PubMed
  3. Nakaminami H, Chen C, Truong-Bolduc QC, Kim ES, Wang Y, Hooper DC. Efflux Transporter of Siderophore Staphyloferrin A in Staphylococcus aureus Contributes to Bacterial Fitness in Abscesses and Epithelial Cells. Infect Immun. 2017 Aug; 85(8). PMID: 28559406.
    View in: PubMed
  4. Shenoy ES, Lee H, Ryan EE, Hou T, Walensky RP, Ware W, Hooper DC. A Discrete Event Simulation Model of Patient Flow in a General Hospital Incorporating Infection Control Policy for Methicillin-Resistant Staphylococcus Aureus (MRSA) and Vancomycin-Resistant Enterococcus (VRE). Med Decis Making. 2017 Jun 01; 272989X17713474. PMID: 28662601.
    View in: PubMed
  5. Truong-Bolduc QC, Khan NS, Vyas JM, Hooper DC. Tet38 Efflux Pump Affects Staphylococcus aureus Internalization by Epithelial Cells through Interaction with CD36 and Contributes to Bacterial Escape from Acidic and Nonacidic Phagolysosomes. Infect Immun. 2017 Feb; 85(2). PMID: 27956597.
    View in: PubMed
  6. Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP. Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks. Proc Natl Acad Sci U S A. 2017 Jan 31; 114(5):1135-1140. PMID: 28096418.
    View in: PubMed
  7. Vinué L, Hooper DC. A simple technique for suppressor detection in Escherichia coli. FEMS Microbiol Lett. 2016 Sep 27. PMID: 27682418.
    View in: PubMed
  8. Hooper DC, Jacoby GA. Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance. Cold Spring Harb Perspect Med. 2016 Sep 01; 6(9). PMID: 27449972.
    View in: PubMed
  9. Obaitan I, Dwyer R, Lipworth AD, Kupper TS, Camargo CA, Hooper DC, Murphy GF, Pallin DJ. Failure of antibiotics in cellulitis trials: a systematic review and meta-analysis. Am J Emerg Med. 2016 Aug; 34(8):1645-52. PMID: 27344098.
    View in: PubMed
  10. Shenoy ES, Lee H, Hou T, Ware W, Ryan EE, Hooper DC, Walensky RP. The Impact of Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococcus (VRE) Flags on Hospital Operations. Infect Control Hosp Epidemiol. 2016 Jul; 37(7):782-90. PMID: 27019995; PMCID: PMC4920697 [Available on 07/01/17].
    View in: PubMed, PubMed Central
  11. Wang Y, Wu X, Chen J, Amin R, Lu M, Bhayana B, Zhao J, Murray CK, Hamblin MR, Hooper DC, Dai T. Antimicrobial Blue Light Inactivation of Gram-Negative Pathogens in Biofilms: In Vitro and In Vivo Studies. J Infect Dis. 2016 May 01; 213(9):1380-7. PMID: 26908743; PMCID: PMC4813746 [Available on 05/01/17].
    View in: PubMed, PubMed Central
  12. Vinué L, Corcoran MA, Hooper DC, Jacoby GA. Mutations That Enhance the Ciprofloxacin Resistance of Escherichia coli with qnrA1. Antimicrob Agents Chemother. 2015 Dec 28; 60(3):1537-45. PMID: 26711751; PMCID: PMC4776012.
    View in: PubMed, PubMed Central
  13. Shenoy ES, Lee H, Cotter JA, Ware W, Kelbaugh D, Weil E, Walensky RP, Hooper DC. Impact of rapid screening for discontinuation of methicillin-resistant Staphylococcus aureus contact precautions. Am J Infect Control. 2016 Feb; 44(2):215-21. PMID: 26440593; PMCID: PMC4728016 [Available on 02/01/17].
    View in: PubMed, PubMed Central
  14. Chen C, Villet R, Jacoby GA, Hooper DC. Functions of a GyrBA fusion protein and its interaction with QnrB and quinolones. Antimicrob Agents Chemother. 2015 Nov; 59(11):7124-7. PMID: 26324265; PMCID: PMC4604398 [Available on 05/01/16].
    View in: PubMed, PubMed Central
  15. Truong-Bolduc QC, Bolduc GR, Medeiros H, Vyas JM, Wang Y, Hooper DC. Role of the Tet38 Efflux Pump in Staphylococcus aureus Internalization and Survival in Epithelial Cells. Infect Immun. 2015 Nov; 83(11):4362-72. PMID: 26324534; PMCID: PMC4598397.
    View in: PubMed, PubMed Central
  16. Paras ML, Shenoy ES, Hsu HE, Walensky RP, Hooper DC. Housestaff Knowledge Related to Urinary Catheter Use and Catheter-Associated Urinary Tract Infections. Infect Control Hosp Epidemiol. 2015 Nov; 36(11):1355-7. PMID: 26278269; PMCID: PMC4615552 [Available on 11/01/16].
    View in: PubMed, PubMed Central
  17. Hooper DC, Jacoby GA. Mechanisms of drug resistance: quinolone resistance. Ann N Y Acad Sci. 2015 Sep; 1354:12-31. PMID: 26190223; PMCID: PMC4626314.
    View in: PubMed, PubMed Central
  18. Kim ES, Chen C, Braun M, Kim HY, Okumura R, Wang Y, Jacoby GA, Hooper DC. Interactions between QnrB, QnrB mutants, and DNA gyrase. Antimicrob Agents Chemother. 2015 Sep; 59(9):5413-9. PMID: 26100716; PMCID: PMC4538543 [Available on 03/01/16].
    View in: PubMed, PubMed Central
  19. Blumenthal KG, Shenoy ES, Varughese CA, Hurwitz S, Hooper DC, Banerji A. Impact of a clinical guideline for prescribing antibiotics to inpatients reporting penicillin or cephalosporin allergy. Ann Allergy Asthma Immunol. 2015 Oct; 115(4):294-300.e2. PMID: 26070805; PMCID: PMC4593731 [Available on 10/01/16].
    View in: PubMed, PubMed Central
  20. Kwak YG, Jacoby GA, Hooper DC. Effect of Qnr on Plasmid Gyrase Toxins CcdB and ParE. Antimicrob Agents Chemother. 2015 Aug; 59(8):5078-9. PMID: 26055367; PMCID: PMC4505230 [Available on 02/01/16].
    View in: PubMed, PubMed Central
  21. Hsu HE, Shenoy ES, Kelbaugh D, Ware W, Lee H, Zakroysky P, Hooper DC, Walensky RP. An electronic surveillance tool for catheter-associated urinary tract infection in intensive care units. Am J Infect Control. 2015 Jun; 43(6):592-9. PMID: 25840717; PMCID: PMC4457697.
    View in: PubMed, PubMed Central
  22. Kim ES, Hooper DC. Clinical importance and epidemiology of quinolone resistance. Infect Chemother. 2014 Dec; 46(4):226-38. PMID: 25566402; PMCID: PMC4285002.
    View in: PubMed, PubMed Central
  23. Calderwood SB, Hooper DC. In memoriam: Morton N. Swartz. J Infect Dis. 2015 Jan 01; 211(1):1-3. PMID: 25030059.
    View in: PubMed
  24. Hooper DC, Hirsch MS. Reply to Korch. J Infect Dis. 2014 Nov 01; 210(9):1517-8. PMID: 24808388.
    View in: PubMed
  25. Youngster I, Shenoy ES, Hooper DC, Nelson SB. Comparative evaluation of the tolerability of cefazolin and nafcillin for treatment of methicillin-susceptible Staphylococcus aureus infections in the outpatient setting. Clin Infect Dis. 2014 Aug 01; 59(3):369-75. PMID: 24785233; PMCID: PMC4110443.
    View in: PubMed, PubMed Central
  26. Blumenthal KG, Shenoy ES, Hurwitz S, Varughese CA, Hooper DC, Banerji A. Effect of a drug allergy educational program and antibiotic prescribing guideline on inpatient clinical providers' antibiotic prescribing knowledge. J Allergy Clin Immunol Pract. 2014 Jul-Aug; 2(4):407-13. PMID: 25017528; PMCID: PMC4309264.
    View in: PubMed, PubMed Central
  27. Tavío MM, Jacoby GA, Hooper DC. QnrS1 structure-activity relationships. J Antimicrob Chemother. 2014 Aug; 69(8):2102-9. PMID: 24729602; PMCID: PMC4100707.
    View in: PubMed, PubMed Central
  28. Shenoy ES, Paras ML, Noubary F, Walensky RP, Hooper DC. Natural history of colonization with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE): a systematic review. BMC Infect Dis. 2014 Mar 31; 14:177. PMID: 24678646; PMCID: PMC4230428.
    View in: PubMed, PubMed Central
  29. Hwang TJ, Hooper DC. Association between fluoroquinolone resistance and resistance to other antimicrobial agents among Escherichia coli urinary isolates in the outpatient setting: a national cross-sectional study. J Antimicrob Chemother. 2014 Jun; 69(6):1720-2. PMID: 24521853.
    View in: PubMed
  30. Villet RA, Truong-Bolduc QC, Wang Y, Estabrooks Z, Medeiros H, Hooper DC. Regulation of expression of abcA and its response to environmental conditions. J Bacteriol. 2014 Apr; 196(8):1532-9. PMID: 24509312; PMCID: PMC3993360.
    View in: PubMed, PubMed Central
  31. Shenoy ES, Noubary F, Kim J, Rosenberg ES, Cotter JA, Lee H, Walensky RP, Hooper DC. Concordance of PCR and culture from nasal swabs for detection of methicillin-resistant Staphylococcus aureus in a setting of concurrent antistaphylococcal antibiotics. J Clin Microbiol. 2014 Apr; 52(4):1235-7. PMID: 24452168; PMCID: PMC3993487.
    View in: PubMed, PubMed Central
  32. Truong-Bolduc QC, Villet RA, Estabrooks ZA, Hooper DC. Native efflux pumps contribute resistance to antimicrobials of skin and the ability of Staphylococcus aureus to colonize skin. J Infect Dis. 2014 May 01; 209(9):1485-93. PMID: 24280365; PMCID: PMC3982850.
    View in: PubMed, PubMed Central
  33. Rebets Y, Lupoli T, Qiao Y, Schirner K, Villet R, Hooper D, Kahne D, Walker S. Moenomycin resistance mutations in Staphylococcus aureus reduce peptidoglycan chain length and cause aberrant cell division. ACS Chem Biol. 2014 Feb 21; 9(2):459-67. PMID: 24255971; PMCID: PMC3944067.
    View in: PubMed, PubMed Central
  34. Hooper DC, Hirsch MS. Novel clostridium botulinum toxin and dual use research of concern issues. J Infect Dis. 2014 Jan 15; 209(2):167. PMID: 24106293; PMCID: PMC3873790.
    View in: PubMed, PubMed Central
  35. Kwak YG, Truong-Bolduc QC, Bin Kim H, Song KH, Kim ES, Hooper DC. Association of norB overexpression and fluoroquinolone resistance in clinical isolates of Staphylococcus aureus from Korea. J Antimicrob Chemother. 2013 Dec; 68(12):2766-72. PMID: 23928023; PMCID: PMC3820107.
    View in: PubMed, PubMed Central
  36. Kwak YG, Jacoby GA, Hooper DC. Induction of plasmid-carried qnrS1 in Escherichia coli by naturally occurring quinolones and quorum-sensing signal molecules. Antimicrob Agents Chemother. 2013 Aug; 57(8):4031-4. PMID: 23689721; PMCID: PMC3719764.
    View in: PubMed, PubMed Central
  37. Shenoy ES, Kim J, Rosenberg ES, Cotter JA, Lee H, Walensky RP, Hooper DC. Discontinuation of contact precautions for methicillin-resistant staphylococcus aureus: a randomized controlled trial comparing passive and active screening with culture and polymerase chain reaction. Clin Infect Dis. 2013 Jul; 57(2):176-84. PMID: 23572482; PMCID: PMC3689342.
    View in: PubMed, PubMed Central
  38. Pallin DJ, Binder WD, Allen MB, Lederman M, Parmar S, Filbin MR, Hooper DC, Camargo CA. Clinical trial: comparative effectiveness of cephalexin plus trimethoprim-sulfamethoxazole versus cephalexin alone for treatment of uncomplicated cellulitis: a randomized controlled trial. Clin Infect Dis. 2013 Jun; 56(12):1754-62. PMID: 23457080.
    View in: PubMed
  39. Jacoby GA, Hooper DC. Phylogenetic analysis of chromosomally determined qnr and related proteins. Antimicrob Agents Chemother. 2013 Apr; 57(4):1930-4. PMID: 23318805; PMCID: PMC3623327.
    View in: PubMed, PubMed Central
  40. Johnson JR, Tchesnokova V, Johnston B, Clabots C, Roberts PL, Billig M, Riddell K, Rogers P, Qin X, Butler-Wu S, Price LB, Aziz M, Nicolas-Chanoine MH, Debroy C, Robicsek A, Hansen G, Urban C, Platell J, Trott DJ, Zhanel G, Weissman SJ, Cookson BT, Fang FC, Limaye AP, Scholes D, Chattopadhyay S, Hooper DC, Sokurenko EV. Abrupt emergence of a single dominant multidrug-resistant strain of Escherichia coli. J Infect Dis. 2013 Mar 15; 207(6):919-28. PMID: 23288927; PMCID: PMC3571447.
    View in: PubMed, PubMed Central
  41. Shenoy ES, Hsu H, Noubary F, Hooper DC, Walensky RP. National survey of infection preventionists: policies for discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus. Infect Control Hosp Epidemiol. 2012 Dec; 33(12):1272-5. PMID: 23143372; PMCID: PMC3496276.
    View in: PubMed, PubMed Central
  42. Ding Y, Fu Y, Lee JC, Hooper DC. Staphylococcus aureus NorD, a putative efflux pump coregulated with the Opp1 oligopeptide permease, contributes selectively to fitness in vivo. J Bacteriol. 2012 Dec; 194(23):6586-93. PMID: 23042988; PMCID: PMC3497520.
    View in: PubMed, PubMed Central
  43. Shenoy ES, Walensky RP, Lee H, Orcutt B, Hooper DC. Resource burden associated with contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus: the patient access managers' perspective. Infect Control Hosp Epidemiol. 2012 Aug; 33(8):849-52. PMID: 22759555; PMCID: PMC3461826.
    View in: PubMed, PubMed Central
  44. Yokoe DS, Khan Y, Olsen MA, Hooper DC, Greenbaum M, Vostok J, Lankiewicz J, Fraser VJ, Stevenson KB. Enhanced surgical site infection surveillance following hysterectomy, vascular, and colorectal surgery. Infect Control Hosp Epidemiol. 2012 Aug; 33(8):768-73. PMID: 22759543.
    View in: PubMed
  45. Hooper DC, DeMaria A, Limbago BM, O'Brien TF, McCaughey B. Antibiotic resistance: how serious is the problem, and what can be done? Clin Chem. 2012 Aug; 58(8):1182-6. PMID: 22634378.
    View in: PubMed
  46. Qualls ML, Mooney MM, Camargo CA, Zucconi T, Hooper DC, Pallin DJ. Emergency department visit rates for abscess versus other skin infections during the emergence of community-associated methicillin-resistant Staphylococcus aureus, 1997-2007. Clin Infect Dis. 2012 Jul; 55(1):103-5. PMID: 22460965.
    View in: PubMed
  47. Bogoch II, Davis BT, Hooper DC. Severe babesiosis in a patient treated with a tumor necrosis factor a antagonist. Clin Infect Dis. 2012 Apr; 54(8):1215-6. PMID: 22354920.
    View in: PubMed
  48. Truong-Bolduc QC, Hsing LC, Villet R, Bolduc GR, Estabrooks Z, Taguezem GF, Hooper DC. Reduced aeration affects the expression of the NorB efflux pump of Staphylococcus aureus by posttranslational modification of MgrA. J Bacteriol. 2012 Apr; 194(7):1823-34. PMID: 22287526; PMCID: PMC3302453.
    View in: PubMed, PubMed Central
  49. Lankiewicz JD, Yokoe DS, Olsen MA, Onufrak F, Fraser VJ, Stevenson K, Khan Y, Hooper D, Platt R, Huang SS. Beyond 30 days: does limiting the duration of surgical site infection follow-up limit detection? Infect Control Hosp Epidemiol. 2012 Feb; 33(2):202-4. PMID: 22227993; PMCID: PMC3608264.
    View in: PubMed, PubMed Central
  50. Calderwood MS, Ma A, Khan YM, Olsen MA, Bratzler DW, Yokoe DS, Hooper DC, Stevenson K, Fraser VJ, Platt R, Huang SS. Use of Medicare diagnosis and procedure codes to improve detection of surgical site infections following hip arthroplasty, knee arthroplasty, and vascular surgery. Infect Control Hosp Epidemiol. 2012 Jan; 33(1):40-9. PMID: 22173521.
    View in: PubMed
  51. Okumura R, Liao CH, Gavin M, Jacoby GA, Hooper DC. Quinolone induction of qnrVS1 in Vibrio splendidus and plasmid-carried qnrS1 in Escherichia coli, a mechanism independent of the SOS system. Antimicrob Agents Chemother. 2011 Dec; 55(12):5942-5. PMID: 21930884; PMCID: PMC3232789.
    View in: PubMed, PubMed Central
  52. Truong-Bolduc QC, Dunman PM, Eidem T, Hooper DC. Transcriptional profiling analysis of the global regulator NorG, a GntR-like protein of Staphylococcus aureus. J Bacteriol. 2011 Nov; 193(22):6207-14. PMID: 21908673; PMCID: PMC3209200.
    View in: PubMed, PubMed Central
  53. Jacoby GA, Griffin CM, Hooper DC. Citrobacter spp. as a source of qnrB Alleles. Antimicrob Agents Chemother. 2011 Nov; 55(11):4979-84. PMID: 21844311; PMCID: PMC3195048.
    View in: PubMed, PubMed Central
  54. Huang SS, Placzek H, Livingston J, Ma A, Onufrak F, Lankiewicz J, Kleinman K, Bratzler D, Olsen MA, Lyles R, Khan Y, Wright P, Yokoe DS, Fraser VJ, Weinstein RA, Stevenson K, Hooper D, Vostok J, Datta R, Nsa W, Platt R. Use of Medicare claims to rank hospitals by surgical site infection risk following coronary artery bypass graft surgery. Infect Control Hosp Epidemiol. 2011 Aug; 32(8):775-83. PMID: 21768761.
    View in: PubMed
  55. Vetting MW, Hegde SS, Wang M, Jacoby GA, Hooper DC, Blanchard JS. Structure of QnrB1, a plasmid-mediated fluoroquinolone resistance factor. J Biol Chem. 2011 Jul 15; 286(28):25265-73. PMID: 21597116; PMCID: PMC3137097.
    View in: PubMed, PubMed Central
  56. Truong-Bolduc QC, Bolduc GR, Okumura R, Celino B, Bevis J, Liao CH, Hooper DC. Implication of the NorB efflux pump in the adaptation of Staphylococcus aureus to growth at acid pH and in resistance to moxifloxacin. Antimicrob Agents Chemother. 2011 Jul; 55(7):3214-9. PMID: 21555767; PMCID: PMC3122426.
    View in: PubMed, PubMed Central
  57. Didier JP, Villet R, Huggler E, Lew DP, Hooper DC, Kelley WL, Vaudaux P. Impact of ciprofloxacin exposure on Staphylococcus aureus genomic alterations linked with emergence of rifampin resistance. Antimicrob Agents Chemother. 2011 May; 55(5):1946-52. PMID: 21357297; PMCID: PMC3088276.
    View in: PubMed, PubMed Central
  58. Kim HB, Park CH, Gavin M, Jacoby GA, Hooper DC. Cold shock induces qnrA expression in Shewanella algae. Antimicrob Agents Chemother. 2011 Jan; 55(1):414-6. PMID: 21078945; PMCID: PMC3019661.
    View in: PubMed, PubMed Central
  59. Hyle EP, Ferraro MJ, Silver M, Lee H, Hooper DC. Ertapenem-resistant Enterobacteriaceae: risk factors for acquisition and outcomes. Infect Control Hosp Epidemiol. 2010 Dec; 31(12):1242-9. PMID: 21029005.
    View in: PubMed
  60. Peleg AY, Hooper DC. Hospital-acquired infections due to gram-negative bacteria. N Engl J Med. 2010 May 13; 362(19):1804-13. PMID: 20463340; PMCID: PMC3107499.
    View in: PubMed, PubMed Central
  61. Truong-Bolduc QC, Hooper DC. Phosphorylation of MgrA and its effect on expression of the NorA and NorB efflux pumps of Staphylococcus aureus. J Bacteriol. 2010 May; 192(10):2525-34. PMID: 20233929; PMCID: PMC2863576.
    View in: PubMed, PubMed Central
  62. Kim HB, Wang M, Ahmed S, Park CH, LaRocque RC, Faruque AS, Salam MA, Khan WA, Qadri F, Calderwood SB, Jacoby GA, Hooper DC. Transferable quinolone resistance in Vibrio cholerae. Antimicrob Agents Chemother. 2010 Feb; 54(2):799-803. PMID: 19949057; PMCID: PMC2812163.
    View in: PubMed, PubMed Central
  63. Hooper DC, Phares TW, Fabis MJ, Roy A. The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system. PLoS Negl Trop Dis. 2009 Oct 06; 3(10):e535. PMID: 19806203; PMCID: PMC2754506.
    View in: PubMed, PubMed Central
  64. Strahilevitz J, Jacoby GA, Hooper DC, Robicsek A. Plasmid-mediated quinolone resistance: a multifaceted threat. Clin Microbiol Rev. 2009 Oct; 22(4):664-89. PMID: 19822894; PMCID: PMC2772364.
    View in: PubMed, PubMed Central
  65. Pallin DJ, Espinola JA, Leung DY, Hooper DC, Camargo CA. Epidemiology of dermatitis and skin infections in United States physicians' offices, 1993-2005. Clin Infect Dis. 2009 Sep 15; 49(6):901-7. PMID: 19663690.
    View in: PubMed
  66. Kim HB, Wang M, Park CH, Kim EC, Jacoby GA, Hooper DC. oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrob Agents Chemother. 2009 Aug; 53(8):3582-4. PMID: 19528276; PMCID: PMC2715617.
    View in: PubMed, PubMed Central
  67. Bolon MK, Hooper D, Stevenson KB, Greenbaum M, Olsen MA, Herwaldt L, Noskin GA, Fraser VJ, Climo M, Khan Y, Vostok J, Yokoe DS. Improved surveillance for surgical site infections after orthopedic implantation procedures: extending applications for automated data. Clin Infect Dis. 2009 May 01; 48(9):1223-9. PMID: 19335165.
    View in: PubMed
  68. Wang M, Guo Q, Xu X, Wang X, Ye X, Wu S, Hooper DC, Wang M. New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob Agents Chemother. 2009 May; 53(5):1892-7. PMID: 19258263; PMCID: PMC2681562.
    View in: PubMed, PubMed Central
  69. Jacoby GA, Gacharna N, Black TA, Miller GH, Hooper DC. Temporal appearance of plasmid-mediated quinolone resistance genes. Antimicrob Agents Chemother. 2009 Apr; 53(4):1665-6. PMID: 19164145; PMCID: PMC2663075.
    View in: PubMed, PubMed Central
  70. Kim HB, Park CH, Kim CJ, Kim EC, Jacoby GA, Hooper DC. Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. Antimicrob Agents Chemother. 2009 Feb; 53(2):639-45. PMID: 19064896; PMCID: PMC2630623.
    View in: PubMed, PubMed Central
  71. Wang M, Jacoby GA, Mills DM, Hooper DC. SOS regulation of qnrB expression. Antimicrob Agents Chemother. 2009 Feb; 53(2):821-3. PMID: 19029320; PMCID: PMC2630627.
    View in: PubMed, PubMed Central
  72. Truong-Bolduc QC, Ding Y, Hooper DC. Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus. J Bacteriol. 2008 Nov; 190(22):7375-81. PMID: 18805983; PMCID: PMC2576658.
    View in: PubMed, PubMed Central
  73. Ding Y, Onodera Y, Lee JC, Hooper DC. NorB, an efflux pump in Staphylococcus aureus strain MW2, contributes to bacterial fitness in abscesses. J Bacteriol. 2008 Nov; 190(21):7123-9. PMID: 18723624; PMCID: PMC2580682.
    View in: PubMed, PubMed Central
  74. Vetting MW, Park CH, Hegde SS, Jacoby GA, Hooper DC, Blanchard JS. Mechanistic and structural analysis of aminoglycoside N-acetyltransferase AAC(6')-Ib and its bifunctional, fluoroquinolone-active AAC(6')-Ib-cr variant. Biochemistry. 2008 Sep 16; 47(37):9825-35. PMID: 18710261; PMCID: PMC2855648.
    View in: PubMed, PubMed Central
  75. Jacoby G, Cattoir V, Hooper D, Martínez-Martínez L, Nordmann P, Pascual A, Poirel L, Wang M. qnr Gene nomenclature. Antimicrob Agents Chemother. 2008 Jul; 52(7):2297-9. PMID: 18426894; PMCID: PMC2443900.
    View in: PubMed, PubMed Central
  76. Pallin DJ, Egan DJ, Pelletier AJ, Espinola JA, Hooper DC, Camargo CA. Increased US emergency department visits for skin and soft tissue infections, and changes in antibiotic choices, during the emergence of community-associated methicillin-resistant Staphylococcus aureus. Ann Emerg Med. 2008 Mar; 51(3):291-8. PMID: 18222564.
    View in: PubMed
  77. Fabis MJ, Scott GS, Kean RB, Koprowski H, Hooper DC. Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5656-61. PMID: 17372191; PMCID: PMC1838442.
    View in: PubMed, PubMed Central
  78. Truong-Bolduc QC, Hooper DC. The transcriptional regulators NorG and MgrA modulate resistance to both quinolones and beta-lactams in Staphylococcus aureus. J Bacteriol. 2007 Apr; 189(8):2996-3005. PMID: 17277059; PMCID: PMC1855827.
    View in: PubMed, PubMed Central
  79. Bhattacharyya T, Hooper DC. Antibiotic dosing before primary hip and knee replacement as a pay-for-performance measure. J Bone Joint Surg Am. 2007 Feb; 89(2):287-91. PMID: 17272442.
    View in: PubMed
  80. Robicsek A, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis. 2006 Oct; 6(10):629-40. PMID: 17008172.
    View in: PubMed
  81. Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC. Prevalence in the United States of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob Agents Chemother. 2006 Nov; 50(11):3953-5. PMID: 16954321; PMCID: PMC1635235.
    View in: PubMed, PubMed Central
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  98. Yokoe DS, Noskin GA, Cunnigham SM, Zuccotti G, Plaskett T, Fraser VJ, Olsen MA, Tokars JI, Solomon S, Perl TM, Cosgrove SE, Tilson RS, Greenbaum M, Hooper DC, Sands KE, Tully J, Herwaldt La, Diekema DJ, Wong ES, Climo M, Platt R. Enhanced identification of postoperative infections among inpatients. Emerg Infect Dis. 2004 Nov; 10(11):1924-30. PMID: 15550201; PMCID: PMC3329006.
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  102. Bisognano C, Kelley WL, Estoppey T, Francois P, Schrenzel J, Li D, Lew DP, Hooper DC, Cheung AL, Vaudaux P. A recA-LexA-dependent pathway mediates ciprofloxacin-induced fibronectin binding in Staphylococcus aureus. J Biol Chem. 2004 Mar 05; 279(10):9064-71. PMID: 14699158.
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  181. Weber DJ, Wolfson JS, Swartz MN, Hooper DC. Pasteurella multocida infections. Report of 34 cases and review of the literature. Medicine (Baltimore). 1984 May; 63(3):133-54. PMID: 6371440.
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  182. Hooper DC, Wolfson JS, McHugh GL, Swartz MD, Tung C, Swartz MN. Elimination of plasmid pMG110 from Escherichia coli by novobiocin and other inhibitors of DNA gyrase. Antimicrob Agents Chemother. 1984 May; 25(5):586-90. PMID: 6329090; PMCID: PMC185592.
    View in: PubMed, PubMed Central
  183. Wolfson JS, Hooper DC, Swartz MN, Swartz MD, McHugh GL. Novobiocin-induced elimination of F'lac and mini-F plasmids from Escherichia coli. J Bacteriol. 1983 Dec; 156(3):1165-70. PMID: 6315678; PMCID: PMC217963.
    View in: PubMed, PubMed Central
  184. Hooper DC, Bayer AS, Karchmer AW, Theofilopoulos AN, Swartz MN. Circulating immune complexes in prosthetic valve endocarditis. Arch Intern Med. 1983 Nov; 143(11):2081-4. PMID: 6639228.
    View in: PubMed
  185. Wolfson JS, Hooper DC, Swartz MN, Swartz MD, McHugh GL. Rapid method for screening large numbers of Escherichia coli colonies for production of plasmid-mediated beta-lactamases. Antimicrob Agents Chemother. 1983 Feb; 23(2):308-12. PMID: 6340605; PMCID: PMC186042.
    View in: PubMed, PubMed Central
  186. Hooper DC, Wolfson JS, McHugh GL, Winters MB, Swartz MN. Effects of novobiocin, coumermycin A1, clorobiocin, and their analogs on Escherichia coli DNA gyrase and bacterial growth. Antimicrob Agents Chemother. 1982 Oct; 22(4):662-71. PMID: 6295263; PMCID: PMC183811.
    View in: PubMed, PubMed Central
  187. Wolfson JS, Hooper DC, Swartz MN, McHugh GL. Antagonism of the B subunit of DNA gyrase eliminates plasmids pBR322 and pMG110 from Escherichia coli. J Bacteriol. 1982 Oct; 152(1):338-44. PMID: 6288663; PMCID: PMC221411.
    View in: PubMed, PubMed Central
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