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Daniel J. Finley, Ph.D.

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Mentoring
Identification of a Hub1 C-terminal Hydrolase from S. cerevisiae
Summer, 06/17/02 - 08/28/02

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL153970 (FINLEY, DANIEL J) Apr 1, 2021 - Mar 31, 2025
    NIH
    Erythrocyte maturation through global remodeling of the proteome
    Role: Principal Investigator
  2. R01HL125710 (FINLEY, DANIEL J) May 15, 2015 - Jun 30, 2019
    NIH
    A novel program of ubiquitination in global remodeling of the erythroid proteome
    Role: Principal Investigator
  3. R21HL116210 (FINLEY, DANIEL J) May 15, 2012 - Oct 30, 2014
    NIH
    Ubiquitination in erythropoiesis and the pathophysiology of anemia
    Role: Principal Investigator
  4. R01GM095526 (FINLEY, DANIEL J) Jun 1, 2011 - May 31, 2016
    NIH
    Ubiquitin chain editing by the mammalian proteasome
    Role: Principal Investigator
  5. R21DK082906 (FINLEY, DANIEL J) Sep 30, 2008 - Jun 30, 2011
    NIH
    Studies of Usp14 and the Ubiquitin Stress Response
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ. ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import. Hum Mol Genet. 2021 Jun 17; 30(13):1230-1246. PMID: 33891006.
    Citations:    Fields:    
  2. Cao C, Prado MA, Sun L, Rockowitz S, Sliz P, Paulo JA, Finley D, Fleming MD. Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy. J Nutr. 2021 05 11; 151(5):1073-1083. PMID: 33693820.
    Citations:    Fields:    Translation:AnimalsCells
  3. Schnell HM, Walsh RM, Rawson S, Kaur M, Bhanu MK, Tian G, Prado MA, Guerra-Moreno A, Paulo JA, Gygi SP, Roelofs J, Finley D, Hanna J. Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat Struct Mol Biol. 2021 05; 28(5):418-425. PMID: 33846632.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Liu Y, Mei Y, Han X, Korobova FV, Prado MA, Yang J, Peng Z, Paulo JA, Gygi SP, Finley D, Ji P. Membrane skeleton modulates erythroid proteome remodeling and organelle clearance. Blood. 2021 01 21; 137(3):398-409. PMID: 33036023.
    Citations:    Fields:    Translation:AnimalsCells
  5. Whiteley AM, Prado MA, de Poot SAH, Paulo JA, Ashton M, Dominguez S, Weber M, Ngu H, Szpyt J, Jedrychowski MP, Easton A, Gygi SP, Kurz T, Monteiro MJ, Brown EJ, Finley D. Global proteomics of Ubqln2-based murine models of ALS. J Biol Chem. 2021 Jan-Jun; 296:100153. PMID: 33277362.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Wu JJ, Cai A, Greenslade JE, Higgins NR, Fan C, Le NTT, Tatman M, Whiteley AM, Prado MA, Dieriks BV, Curtis MA, Shaw CE, Siddique T, Faull RLM, Scotter EL, Finley D, Monteiro MJ. ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15230-15241. PMID: 32513711.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  7. Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, Bernstein BE, Lane AA. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020 03 16; 11(1):1406. PMID: 32179749.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Li Y, Lan Q, Gao Y, Xu C, Xu Z, Wang Y, Chang L, Wu J, Deng Z, He F, Finley D, Xu P. Ubiquitin Linkage Specificity of Deubiquitinases Determines Cyclophilin Nuclear Localization and Degradation. iScience. 2020 Apr 24; 23(4):100984. PMID: 32240951.
    Citations: 2     
  9. Dukovski D, Villella A, Bastos C, King R, Finley D, Kelly JW, Morimoto RI, Hartl FU, Munoz B, Lee PS, Zecevic M, Miller JP. Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA. J Cyst Fibros. 2020 09; 19(5):733-741. PMID: 32067958.
    Citations: 6     Fields:    Translation:Humans
  10. Zuo Y, Chong BK, Jiang K, Finley D, Klenerman D, Ye Y. A General in Vitro Assay for Studying Enzymatic Activities of the Ubiquitin System. Biochemistry. 2020 02 25; 59(7):851-861. PMID: 31951392.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Martinez-Fonts K, Davis C, Tomita T, Elsasser S, Nager AR, Shi Y, Finley D, Matouschek A. The proteasome 19S cap and its ubiquitin receptors provide a versatile recognition platform for substrates. Nat Commun. 2020 01 24; 11(1):477. PMID: 31980598.
    Citations: 20     Fields:    Translation:Cells
  12. Finley D, Prado MA. The Proteasome and Its Network: Engineering for Adaptability. Cold Spring Harb Perspect Biol. 2020 01 02; 12(1). PMID: 30833452.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  13. Guerra-Moreno A, Prado MA, Ang J, Schnell HM, Micoogullari Y, Paulo JA, Finley D, Gygi SP, Hanna J. Thiol-based direct threat sensing by the stress-activated protein kinase Hog1. Sci Signal. 2019 11 26; 12(609). PMID: 31772124.
    Citations: 1     Fields:    Translation:AnimalsCells
  14. Ye Y, Klenerman D, Finley D. N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of Their Oligomers by the Proteasome Holoenzyme. J Mol Biol. 2020 01 17; 432(2):585-596. PMID: 31518613.
    Citations: 10     Fields:    Translation:HumansCells
  15. Massa F, Tammaro R, Prado MA, Cesana M, Lee BH, Finley D, Franco B, Morleo M. The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling. Hum Mol Genet. 2019 03 01; 28(5):764-777. PMID: 30388222.
    Citations: 10     Fields:    Translation:AnimalsCells
  16. Cliffe R, Sang JC, Kundel F, Finley D, Klenerman D, Ye Y. Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme. Cell Rep. 2019 02 19; 26(8):2140-2149.e3. PMID: 30784595.
    Citations: 10     Fields:    Translation:HumansCells
  17. Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y. Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature. 2019 01; 565(7737):49-55. PMID: 30479383.
    Citations: 75     Fields:    Translation:HumansCells
  18. Bretones G, Álvarez MG, Arango JR, Rodríguez D, Nadeu F, Prado MA, Valdés-Mas R, Puente DA, Paulo JA, Delgado J, Villamor N, López-Guillermo A, Finley DJ, Gygi SP, Campo E, Quesada V, López-Otín C. Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia. Blood. 2018 11 29; 132(22):2375-2388. PMID: 30181176.
    Citations: 13     Fields:    Translation:HumansCells
  19. de Poot SAH, Tian G, Finley D. Meddling with Fate: The Proteasomal Deubiquitinating Enzymes. J Mol Biol. 2017 11 10; 429(22):3525-3545. PMID: 28988953.
    Citations: 32     Fields:    Translation:Cells
  20. Boselli M, Lee BH, Robert J, Prado MA, Min SW, Cheng C, Silva MC, Seong C, Elsasser S, Hatle KM, Gahman TC, Gygi SP, Haggarty SJ, Gan L, King RW, Finley D. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 11 24; 292(47):19209-19225. PMID: 28972160.
    Citations: 42     Fields:    Translation:AnimalsCells
  21. Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, Finley D, Brown EJ. Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins. Elife. 2017 09 21; 6. PMID: 28933694.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  22. Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, Min M, Campagna DR, Tian G, Shi Y, Dederer V, Kawan M, Kuehnle N, Paulo JA, Yao Y, Weiss MJ, Justice MJ, Gygi SP, Fleming MD, Finley D. UBE2O remodels the proteome during terminal erythroid differentiation. Science. 2017 08 04; 357(6350). PMID: 28774900.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  23. Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y. Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol Cell. 2017 Jul 20; 67(2):322-333.e6. PMID: 28689658.
    Citations: 9     Fields:    Translation:HumansCells
  24. Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017 07 03; 216(7):2027-2045. PMID: 28566324.
    Citations: 190     Fields:    Translation:HumansAnimalsCells
  25. Peng H, Yang J, Li G, You Q, Han W, Li T, Gao D, Xie X, Lee BH, Du J, Hou J, Zhang T, Rao H, Huang Y, Li Q, Zeng R, Hui L, Wang H, Xia Q, Zhang X, He Y, Komatsu M, Dikic I, Finley D, Hu R. Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell Res. 2017 May; 27(5):657-674. PMID: 28322253.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  26. Li F, Tian G, Langager D, Sokolova V, Finley D, Park S. Nucleotide-dependent switch in proteasome assembly mediated by the Nas6 chaperone. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):1548-1553. PMID: 28137839.
    Citations: 7     Fields:    Translation:AnimalsCells
  27. Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y. Structural basis for dynamic regulation of the human 26S proteasome. Proc Natl Acad Sci U S A. 2016 11 15; 113(46):12991-12996. PMID: 27791164.
    Citations: 60     Fields:    Translation:HumansCells
  28. Rose CM, Isasa M, Ordureau A, Prado MA, Beausoleil SA, Jedrychowski MP, Finley DJ, Harper JW, Gygi SP. Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes. Cell Syst. 2016 10 26; 3(4):395-403.e4. PMID: 27667366.
    Citations: 48     Fields:    Translation:AnimalsCells
  29. Lee BH, Lu Y, Prado MA, Shi Y, Tian G, Sun S, Elsasser S, Gygi SP, King RW, Finley D. USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites. Nature. 2016 Apr 21; 532(7599):398-401. PMID: 27074503.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  30. Choi WH, de Poot SA, Lee JH, Kim JH, Han DH, Kim YK, Finley D, Lee MJ. Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. Nat Commun. 2016 Mar 09; 7:10963. PMID: 26957043.
    Citations: 30     Fields:    Translation:HumansCells
  31. Luan B, Huang X, Wu J, Mei Z, Wang Y, Xue X, Yan C, Wang J, Finley DJ, Shi Y, Wang F. Structure of an endogenous yeast 26S proteasome reveals two major conformational states. Proc Natl Acad Sci U S A. 2016 Mar 08; 113(10):2642-7. PMID: 26929360.
    Citations: 32     Fields:    Translation:AnimalsCells
  32. Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, Walters KJ. Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome. Science. 2016 Feb 19; 351(6275). PMID: 26912900.
    Citations: 90     Fields:    Translation:AnimalsCells
  33. Finley D, Chen X, Walters KJ. Gates, Channels, and Switches: Elements of the Proteasome Machine. Trends Biochem Sci. 2016 Jan; 41(1):77-93. PMID: 26643069.
    Citations: 102     Fields:    Translation:HumansCells
  34. Isasa M, Rose CM, Elsasser S, Navarrete-Perea J, Paulo JA, Finley DJ, Gygi SP. Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains. J Proteome Res. 2015 Dec 04; 14(12):5306-17. PMID: 26503604.
    Citations: 19     Fields:    Translation:AnimalsCells
  35. Xu D, Shan B, Lee BH, Zhu K, Zhang T, Sun H, Liu M, Shi L, Liang W, Qian L, Xiao J, Wang L, Pan L, Finley D, Yuan J. Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. Elife. 2015 Nov 02; 4:e10510. PMID: 26523394.
    Citations: 39     Fields:    Translation:HumansCells
  36. Lu Y, Lee BH, King RW, Finley D, Kirschner MW. Substrate degradation by the proteasome: a single-molecule kinetic analysis. Science. 2015 Apr 10; 348(6231):1250834. PMID: 25859050.
    Citations: 83     Fields:    Translation:HumansCells
  37. Silva GM, Finley D, Vogel C. K63 polyubiquitination is a new modulator of the oxidative stress response. Nat Struct Mol Biol. 2015 Feb; 22(2):116-23. PMID: 25622294.
    Citations: 73     Fields:    Translation:AnimalsCells
  38. King RW, Finley D. Sculpting the proteome with small molecules. Nat Chem Biol. 2014 Nov; 10(11):870-4. PMID: 25325686.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  39. Liu Z, Chen P, Gao H, Gu Y, Yang J, Peng H, Xu X, Wang H, Yang M, Liu X, Fan L, Chen S, Zhou J, Sun Y, Ruan K, Cheng S, Komatsu M, White E, Li L, Ji H, Finley D, Hu R. Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression. Cancer Cell. 2014 Jul 14; 26(1):106-20. PMID: 25026213.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  40. Liu YP, Tsai IC, Morleo M, Oh EC, Leitch CC, Massa F, Lee BH, Parker DS, Finley D, Zaghloul NA, Franco B, Katsanis N. Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. J Clin Invest. 2014 May; 124(5):2059-70. PMID: 24691443.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  41. Tar K, Dange T, Yang C, Yao Y, Bulteau AL, Salcedo EF, Braigen S, Bouillaud F, Finley D, Schmidt M. Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1. J Biol Chem. 2014 Apr 25; 289(17):12145-12156. PMID: 24604417.
    Citations: 17     Fields:    Translation:AnimalsCells
  42. Tar K, Dange T, Yang C, Yao Y, Bulteau AL, Fernandez Salcedo E, Braigen S, Bouillaud F, Finley D, Schmidt M. WITHDRAWN: Blm10-proteasomes antagonize mitochondrial fission through degradation of Dnm1. J Biol Chem. 2014 Jan 08. PMID: 24285543.
    Citations:    Fields:    
  43. Hanna J, Waterman D, Isasa M, Elsasser S, Shi Y, Gygi S, Finley D. Cuz1/Ynl155w, a zinc-dependent ubiquitin-binding protein, protects cells from metalloid-induced proteotoxicity. J Biol Chem. 2014 Jan 17; 289(3):1876-85. PMID: 24297164.
    Citations: 8     Fields:    Translation:AnimalsCells
  44. Schmidt M, Finley D. Regulation of proteasome activity in health and disease. Biochim Biophys Acta. 2014 Jan; 1843(1):13-25. PMID: 23994620.
    Citations: 163     Fields:    Translation:HumansAnimalsCells
  45. Park S, Li X, Kim HM, Singh CR, Tian G, Hoyt MA, Lovell S, Battaile KP, Zolkiewski M, Coffino P, Roelofs J, Cheng Y, Finley D. Reconfiguration of the proteasome during chaperone-mediated assembly. Nature. 2013 May 23; 497(7450):512-6. PMID: 23644457.
    Citations: 33     Fields:    Translation:AnimalsCells
  46. Ehlinger A, Park S, Fahmy A, Lary JW, Cole JL, Finley D, Walters KJ. Conformational dynamics of the Rpt6 ATPase in proteasome assembly and Rpn14 binding. Structure. 2013 May 07; 21(5):753-65. PMID: 23562395.
    Citations: 11     Fields:    Translation:AnimalsCells
  47. Lee BH, Finley D, King RW. A High-Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14. Curr Protoc Chem Biol. 2012 Dec 01; 4(4):311-30. PMID: 23788557.
    Citations: 13     Fields:    
  48. Finley D, Ulrich HD, Sommer T, Kaiser P. The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics. 2012 Oct; 192(2):319-60. PMID: 23028185.
    Citations: 160     Fields:    Translation:AnimalsCells
  49. Matouschek A, Finley D. Cell biology. An ancient portal to proteolysis. Science. 2012 Aug 17; 337(6096):813-4. PMID: 22904006.
    Citations: 2     Fields:    Translation:Cells
  50. Hanna J, Waterman D, Boselli M, Finley D. Spg5 protein regulates the proteasome in quiescence. J Biol Chem. 2012 Oct 05; 287(41):34400-9. PMID: 22904326.
    Citations: 8     Fields:    Translation:Animals
  51. Tian G, Finley D. Cell biology: Destruction deconstructed. Nature. 2012 Feb 08; 482(7384):170-1. PMID: 22318600.
    Citations: 2     Fields:    Translation:Animals
  52. Dimova NV, Hathaway NA, Lee BH, Kirkpatrick DS, Berkowitz ML, Gygi SP, Finley D, King RW. APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nat Cell Biol. 2012 Jan 29; 14(2):168-76. PMID: 22286100.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  53. Nag DK, Finley D. A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication. Virus Res. 2012 Apr; 165(1):103-6. PMID: 22306365.
    Citations: 20     Fields:    Translation:HumansCells
  54. Elsasser S, Shi Y, Finley D. Binding of ubiquitin conjugates to proteasomes as visualized with native gels. Methods Mol Biol. 2012; 832:403-22. PMID: 22350901.
    Citations: 4     Fields:    Translation:AnimalsCells
  55. Chen PC, Bhattacharyya BJ, Hanna J, Minkel H, Wilson JA, Finley D, Miller RJ, Wilson SM. Ubiquitin homeostasis is critical for synaptic development and function. J Neurosci. 2011 Nov 30; 31(48):17505-13. PMID: 22131412.
    Citations: 48     Fields:    Translation:AnimalsCells
  56. Tian G, Park S, Lee MJ, Huck B, McAllister F, Hill CP, Gygi SP, Finley D. An asymmetric interface between the regulatory and core particles of the proteasome. Nat Struct Mol Biol. 2011 Oct 30; 18(11):1259-67. PMID: 22037170.
    Citations: 41     Fields:    Translation:AnimalsCells
  57. Dange T, Smith D, Noy T, Rommel PC, Jurzitza L, Cordero RJ, Legendre A, Finley D, Goldberg AL, Schmidt M. Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism. J Biol Chem. 2011 Dec 16; 286(50):42830-9. PMID: 22025621.
    Citations: 39     Fields:    Translation:AnimalsCells
  58. Finley D. Misfolded proteins driven to destruction by Hul5. Nat Cell Biol. 2011 Oct 09; 13(11):1290-2. PMID: 21983564.
    Citations: 8     Fields:    Translation:AnimalsCells
  59. Park S, Kim W, Tian G, Gygi SP, Finley D. Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress response. J Biol Chem. 2011 Oct 21; 286(42):36652-66. PMID: 21878652.
    Citations: 37     Fields:    Translation:AnimalsCells
  60. Lee BH, Lee MJ, Park S, Oh DC, Elsasser S, Chen PC, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D. Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature. 2010 Sep 09; 467(7312):179-84. PMID: 20829789.
    Citations: 411     Fields:    Translation:HumansAnimalsCells
  61. Lee MJ, Lee BH, Hanna J, King RW, Finley D. Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes. Mol Cell Proteomics. 2011 May; 10(5):R110.003871. PMID: 20823120.
    Citations: 116     Fields:    Translation:HumansAnimals
  62. Isasa M, Katz EJ, Kim W, Yugo V, González S, Kirkpatrick DS, Thomson TM, Finley D, Gygi SP, Crosas B. Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome. Mol Cell. 2010 Jun 11; 38(5):733-45. PMID: 20542005.
    Citations: 69     Fields:    Translation:AnimalsCells
  63. Chen X, Lee BH, Finley D, Walters KJ. Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2. Mol Cell. 2010 May 14; 38(3):404-15. PMID: 20471946.
    Citations: 59     Fields:    Translation:HumansCells
  64. Park S, Tian G, Roelofs J, Finley D. Assembly manual for the proteasome regulatory particle: the first draft. Biochem Soc Trans. 2010 Feb; 38(Pt 1):6-13. PMID: 20074027.
    Citations: 15     Fields:    Translation:AnimalsCells
  65. Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, McGary VT, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson RH, Nienaber P, Nowak JA, Osmanov B, Ouedraogo S, Patterson RB, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Soderberg M, Sorel M, Spentzouris P, Spitz J, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water R, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED. Measurement of the ratio of the numu charged-current single-pion production to quasielastic scattering with a 0.8 GeV neutrino beam on mineral oil. Phys Rev Lett. 2009 Aug 21; 103(8):081801. PMID: 19792715.
    Citations:    Fields:    
  66. Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Grange J, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, Mauger C, McGary VT, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Mousseau J, Nelson RH, Nienaber P, Nowak JA, Osmanov B, Ouedraogo S, Patterson RB, Pavlovic Z, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Soderberg M, Sorel M, Spentzouris P, Spitz J, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water RG, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED. Search for muon neutrino and antineutrino disappearance in MiniBooNE. Phys Rev Lett. 2009 Aug 07; 103(6):061802. PMID: 19792551.
    Citations:    Fields:    
  67. Roelofs J, Park S, Haas W, Tian G, McAllister FE, Huo Y, Lee BH, Zhang F, Shi Y, Gygi SP, Finley D. Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature. 2009 Jun 11; 459(7248):861-5. PMID: 19412159.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  68. Park S, Roelofs J, Kim W, Robert J, Schmidt M, Gygi SP, Finley D. Hexameric assembly of the proteasomal ATPases is templated through their C termini. Nature. 2009 Jun 11; 459(7248):866-70. PMID: 19412160.
    Citations: 76     Fields:    Translation:Animals
  69. Adamson P, Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Bishai M, Brice SJ, Brown BC, Bugel L, Cao J, Choudhary BC, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Gallagher HR, Garcia FG, Garvey GT, Green C, Green JA, Harris D, Hart TL, Hawker E, Hylen J, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kopp S, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Loiacono L, Louis WC, Marchionni A, Mahn KB, Marsh W, McGregor G, Messier MD, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson JK, Nelson RH, Nguyen VT, Nienaber P, Nowak JA, Ouedraogo S, Patterson RB, Pavlovic Z, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smart W, Smith D, Sodeberg M, Sorel M, Spentzouris P, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Vahle P, Van de Water R, Viren B, Wascko MO, White DH, Wilking MJ, Yang HJ, Yumiceva FX, Zeller GP, Zimmerman ED, Zwaska R. Measurement of numicro and nue events in an off-axis horn-focused neutrino beam. Phys Rev Lett. 2009 May 29; 102(21):211801. PMID: 19519094.
    Citations:    Fields:    
  70. Zhang F, Wu Z, Zhang P, Tian G, Finley D, Shi Y. Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell. 2009 May 14; 34(4):485-96. PMID: 19481528.
    Citations: 51     Fields:    Translation:Cells
  71. Zhang F, Hu M, Tian G, Zhang P, Finley D, Jeffrey PD, Shi Y. Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell. 2009 May 14; 34(4):473-84. PMID: 19481527.
    Citations: 99     Fields:    Translation:HumansCells
  72. Xu P, Duong DM, Seyfried NT, Cheng D, Xie Y, Robert J, Rush J, Hochstrasser M, Finley D, Peng J. Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell. 2009 Apr 03; 137(1):133-45. PMID: 19345192.
    Citations: 483     Fields:    Translation:AnimalsCells
  73. Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson RH, Nguyen VT, Nienaber P, Nowak JA, Ouedraogo S, Patterson RB, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Sodeberg M, Sorel M, Spentzouris P, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water R, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED. Unexplained excess of electronlike events from a 1-GeV neutrino beam. Phys Rev Lett. 2009 Mar 13; 102(10):101802. PMID: 19392103.
    Citations:    Fields:    
  74. Finley D. Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu Rev Biochem. 2009; 78:477-513. PMID: 19489727.
    Citations: 694     Fields:    Translation:HumansAnimals
  75. Husnjak K, Elsasser S, Zhang N, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D, Dikic I. Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature. 2008 May 22; 453(7194):481-8. PMID: 18497817.
    Citations: 299     Fields:    Translation:HumansAnimalsCells
  76. Schreiner P, Chen X, Husnjak K, Randles L, Zhang N, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M. Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature. 2008 May 22; 453(7194):548-52. PMID: 18497827.
    Citations: 162     Fields:    Translation:HumansAnimalsCells
  77. Goh AM, Walters KJ, Elsasser S, Verma R, Deshaies RJ, Finley D, Howley PM. Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins. BMC Biochem. 2008 Jan 30; 9:4. PMID: 18234089.
    Citations: 13     Fields:    Translation:HumansCells
  78. Aguilar-Arevalo AA, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, Martin PS, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson RH, Nienaber P, Ouedraogo S, Patterson RB, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Sorel M, Spentzouris P, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water R, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED. Measurement of muon neutrino quasielastic scattering on carbon. Phys Rev Lett. 2008 Jan 25; 100(3):032301. PMID: 18232974.
    Citations: 1     Fields:    
  79. Kleijnen MF, Roelofs J, Park S, Hathaway NA, Glickman M, King RW, Finley D. Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites. Nat Struct Mol Biol. 2007 Dec; 14(12):1180-8. PMID: 18026118.
    Citations: 86     Fields:    Translation:Cells
  80. Smith DM, Chang SC, Park S, Finley D, Cheng Y, Goldberg AL. Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell. 2007 Sep 07; 27(5):731-44. PMID: 17803938.
    Citations: 234     Fields:    Translation:AnimalsCells
  81. Aguilar-Arevalo AA, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, Martin PS, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson RH, Nienaber P, Ouedraogo S, Patterson RB, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Sorel M, Spentzouris P, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water R, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED. Search for electron neutrino appearance at the Delta m2 approximately 1 eV2 scale. Phys Rev Lett. 2007 Jun 08; 98(23):231801. PMID: 17677898.
    Citations: 3     Fields:    
  82. Hanna J, Meides A, Zhang DP, Finley D. A ubiquitin stress response induces altered proteasome composition. Cell. 2007 May 18; 129(4):747-59. PMID: 17512408.
    Citations: 93     Fields:    Translation:AnimalsCells
  83. Hanna J, Finley D. A proteasome for all occasions. FEBS Lett. 2007 Jun 19; 581(15):2854-61. PMID: 17418826.
    Citations: 69     Fields:    Translation:HumansAnimals
  84. Crosas B, Hanna J, Kirkpatrick DS, Zhang DP, Tone Y, Hathaway NA, Buecker C, Leggett DS, Schmidt M, King RW, Gygi SP, Finley D. Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. Cell. 2006 Dec 29; 127(7):1401-13. PMID: 17190603.
    Citations: 144     Fields:    Translation:Animals
  85. Hanna J, Hathaway NA, Tone Y, Crosas B, Elsasser S, Kirkpatrick DS, Leggett DS, Gygi SP, King RW, Finley D. Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. Cell. 2006 Oct 06; 127(1):99-111. PMID: 17018280.
    Citations: 169     Fields:    Translation:HumansAnimals
  86. Kirkpatrick DS, Hathaway NA, Hanna J, Elsasser S, Rush J, Finley D, King RW, Gygi SP. Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology. Nat Cell Biol. 2006 Jul; 8(7):700-10. PMID: 16799550.
    Citations: 198     Fields:    Translation:AnimalsCells
  87. Elsasser S, Finley D. Delivery of ubiquitinated substrates to protein-unfolding machines. Nat Cell Biol. 2005 Aug; 7(8):742-9. PMID: 16056265.
    Citations: 163     Fields:    Translation:HumansAnimalsCells
  88. Schmidt M, Hanna J, Elsasser S, Finley D. Proteasome-associated proteins: regulation of a proteolytic machine. Biol Chem. 2005 Aug; 386(8):725-37. PMID: 16201867.
    Citations: 72     Fields:    Translation:Cells
  89. Shang F, Deng G, Liu Q, Guo W, Haas AL, Crosas B, Finley D, Taylor A. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem. 2005 May 27; 280(21):20365-74. PMID: 15790562.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  90. Schmidt M, Haas W, Crosas B, Santamaria PG, Gygi SP, Walz T, Finley D. The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol. 2005 Apr; 12(4):294-303. PMID: 15778719.
    Citations: 87     Fields:    Translation:AnimalsCells
  91. Leggett DS, Glickman MH, Finley D. Purification of proteasomes, proteasome subcomplexes, and proteasome-associated proteins from budding yeast. Methods Mol Biol. 2005; 301:57-70. PMID: 15917626.
    Citations: 50     Fields:    Translation:Animals
  92. Elsasser S, Schmidt M, Finley D. Characterization of the proteasome using native gel electrophoresis. Methods Enzymol. 2005; 398:353-63. PMID: 16275342.
    Citations: 81     Fields:    Translation:Animals
  93. Wilkinson CR, Dittmar GA, Ohi MD, Uetz P, Jones N, Finley D. Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast. Curr Biol. 2004 Dec 29; 14(24):2283-8. PMID: 15620657.
    Citations: 21     Fields:    Translation:AnimalsCells
  94. Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, Jentsch S, Johnson E, Kwon YT, Pagano M, Pickart C, Rechsteiner M, Scheffner M, Sommer T, Tansey W, Tyers M, Vierstra R, Weissman A, Wilkinson KD, Wolf D. Varshavsky's contributions. Science. 2004 Nov 19; 306(5700):1290-2. PMID: 15550643.
    Citations:    Fields:    
  95. Newman RM, Mobascher A, Mangold U, Koike C, Diah S, Schmidt M, Finley D, Zetter BR. Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression. J Biol Chem. 2004 Oct 01; 279(40):41504-11. PMID: 15277517.
    Citations: 52     Fields:    Translation:AnimalsCells
  96. Elsasser S, Chandler-Militello D, Müller B, Hanna J, Finley D. Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome. J Biol Chem. 2004 Jun 25; 279(26):26817-22. PMID: 15117949.
    Citations: 138     Fields:    Translation:AnimalsCells
  97. Janse DM, Crosas B, Finley D, Church GM. Localization to the proteasome is sufficient for degradation. J Biol Chem. 2004 May 14; 279(20):21415-20. PMID: 15039430.
    Citations: 43     Fields:    
  98. Finley D, Ciechanover A, Varshavsky A. Ubiquitin as a central cellular regulator. Cell. 2004 Jan 23; 116(2 Suppl):S29-32, 2 p following S32. PMID: 15055578.
    Citations: 45     Fields:    Translation:Cells
  99. Hanna J, Leggett DS, Finley D. Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Mol Cell Biol. 2003 Dec; 23(24):9251-61. PMID: 14645527.
    Citations: 103     Fields:    Translation:AnimalsCells
  100. Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP. A proteomics approach to understanding protein ubiquitination. Nat Biotechnol. 2003 Aug; 21(8):921-6. PMID: 12872131.
    Citations: 600     Fields:    Translation:Cells
  101. Bajorek M, Finley D, Glickman MH. Proteasome disassembly and downregulation is correlated with viability during stationary phase. Curr Biol. 2003 Jul 01; 13(13):1140-4. PMID: 12842014.
    Citations: 59     Fields:    Translation:AnimalsCells
  102. Santamaria PG, Finley D, Ballesta JP, Remacha M. Rpn6p, a proteasome subunit from Saccharomyces cerevisiae, is essential for the assembly and activity of the 26 S proteasome. J Biol Chem. 2003 Feb 28; 278(9):6687-95. PMID: 12486135.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  103. Elsasser S, Gali RR, Schwickart M, Larsen CN, Leggett DS, Müller B, Feng MT, Tübing F, Dittmar GA, Finley D. Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol. 2002 Sep; 4(9):725-30. PMID: 12198498.
    Citations: 170     Fields:    Translation:Cells
  104. Leggett DS, Hanna J, Borodovsky A, Crosas B, Schmidt M, Baker RT, Walz T, Ploegh H, Finley D. Multiple associated proteins regulate proteasome structure and function. Mol Cell. 2002 Sep; 10(3):495-507. PMID: 12408819.
    Citations: 257     Fields:    Translation:AnimalsCells
  105. Finley D. Ubiquitin chained and crosslinked. Nat Cell Biol. 2002 May; 4(5):E121-3. PMID: 11988752.
    Citations: 5     Fields:    Translation:Cells
  106. Dittmar GA, Wilkinson CR, Jedrzejewski PT, Finley D. Role of a ubiquitin-like modification in polarized morphogenesis. Science. 2002 Mar 29; 295(5564):2442-6. PMID: 11923536.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  107. Jarosch E, Taxis C, Volkwein C, Bordallo J, Finley D, Wolf DH, Sommer T. Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat Cell Biol. 2002 Feb; 4(2):134-9. PMID: 11813000.
    Citations: 204     Fields:    Translation:Cells
  108. Finley D. Signal transduction. An alternative to destruction. Nature. 2001 Jul 19; 412(6844):283, 285-6. PMID: 11460144.
    Citations: 4     Fields:    Translation:Cells
  109. Köhler A, Cascio P, Leggett DS, Woo KM, Goldberg AL, Finley D. The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release. Mol Cell. 2001 Jun; 7(6):1143-52. PMID: 11430818.
    Citations: 118     Fields:    Translation:AnimalsCells
  110. Köhler A, Bajorek M, Groll M, Moroder L, Rubin DM, Huber R, Glickman MH, Finley D. The substrate translocation channel of the proteasome. Biochimie. 2001 Mar-Apr; 83(3-4):325-32. PMID: 11295493.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  111. Groll M, Bajorek M, Köhler A, Moroder L, Rubin DM, Huber R, Glickman MH, Finley D. A gated channel into the proteasome core particle. Nat Struct Biol. 2000 Nov; 7(11):1062-7. PMID: 11062564.
    Citations: 265     Fields:    Translation:HumansAnimalsCells
  112. Spence J, Gali RR, Dittmar G, Sherman F, Karin M, Finley D. Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain. Cell. 2000 Jul 07; 102(1):67-76. PMID: 10929714.
    Citations: 115     Fields:    Translation:HumansAnimalsCells
  113. Schmidt M, Lupas AN, Finley D. Structure and mechanism of ATP-dependent proteases. Curr Opin Chem Biol. 1999 Oct; 3(5):584-91. PMID: 10508673.
    Citations: 16     Fields:    
  114. Horwich AL, Weber-Ban EU, Finley D. Chaperone rings in protein folding and degradation. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11033-40. PMID: 10500119.
    Citations: 47     Fields:    Translation:Cells
  115. Braun BC, Glickman M, Kraft R, Dahlmann B, Kloetzel PM, Finley D, Schmidt M. The base of the proteasome regulatory particle exhibits chaperone-like activity. Nat Cell Biol. 1999 Aug; 1(4):221-6. PMID: 10559920.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  116. Glickman MH, Rubin DM, Fu H, Larsen CN, Coux O, Wefes I, Pfeifer G, Cjeka Z, Vierstra R, Baumeister W, Fried V, Finley D. Functional analysis of the proteasome regulatory particle. Mol Biol Rep. 1999 Apr; 26(1-2):21-8. PMID: 10363642.
    Citations: 25     Fields:    Translation:HumansAnimals
  117. Fu H, Girod PA, Doelling JH, van Nocker S, Hochstrasser M, Finley D, Vierstra RD. Structure and functional analysis of the 26S proteasome subunits from plants. Mol Biol Rep. 1999 Apr; 26(1-2):137-46. PMID: 10363660.
    Citations: 13     Fields:    Translation:Animals
  118. Glickman MH, Rubin DM, Coux O, Wefes I, Pfeifer G, Cjeka Z, Baumeister W, Fried VA, Finley D. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell. 1998 Sep 04; 94(5):615-23. PMID: 9741626.
    Citations: 278     Fields:    Translation:AnimalsCells
  119. Rubin DM, Glickman MH, Larsen CN, Dhruvakumar S, Finley D. Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J. 1998 Sep 01; 17(17):4909-19. PMID: 9724628.
    Citations: 106     Fields:    Translation:AnimalsCells
  120. Glickman MH, Rubin DM, Fried VA, Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol. 1998 Jun; 18(6):3149-62. PMID: 9584156.
    Citations: 156     Fields:    Translation:AnimalsCells
  121. Sears C, Olesen J, Rubin D, Finley D, Maniatis T. NF-kappa B p105 processing via the ubiquitin-proteasome pathway. J Biol Chem. 1998 Jan 16; 273(3):1409-19. PMID: 9430676.
    Citations: 17     Fields:    Translation:AnimalsCells
  122. Larsen CN, Finley D. Protein translocation channels in the proteasome and other proteases. Cell. 1997 Nov 14; 91(4):431-4. PMID: 9390550.
    Citations: 40     Fields:    
  123. Rubin DM, van Nocker S, Glickman M, Coux O, Wefes I, Sadis S, Fu H, Goldberg A, Vierstra R, Finley D. ATPase and ubiquitin-binding proteins of the yeast proteasome. Mol Biol Rep. 1997 Mar; 24(1-2):17-26. PMID: 9228276.
    Citations: 8     Fields:    Translation:AnimalsCells
  124. Yaglom JA, Goldberg AL, Finley D, Sherman MY. The molecular chaperone Ydj1 is required for the p34CDC28-dependent phosphorylation of the cyclin Cln3 that signals its degradation. Mol Cell Biol. 1996 Jul; 16(7):3679-84. PMID: 8668184.
    Citations: 28     Fields:    Translation:AnimalsCells
  125. Rubin DM, Coux O, Wefes I, Hengartner C, Young RA, Goldberg AL, Finley D. Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome. Nature. 1996 Feb 15; 379(6566):655-7. PMID: 8628401.
    Citations: 42     Fields:    Translation:AnimalsCells
  126. Wefes I, Kaiser P, Schneider R, Pickart CM, Finley D. Characterization of a cDNA clone encoding E2-20K, a murine ubiquitin-conjugating enzyme. Gene. 1995 Oct 03; 163(2):321-2. PMID: 7590289.
    Citations: 1     Fields:    Translation:AnimalsCells
  127. Sadis S, Atienza C, Finley D. Synthetic signals for ubiquitin-dependent proteolysis. Mol Cell Biol. 1995 Aug; 15(8):4086-94. PMID: 7623804.
    Citations: 19     Fields:    Translation:Cells
  128. Rubin DM, Finley D. Proteolysis. The proteasome: a protein-degrading organelle? Curr Biol. 1995 Aug 01; 5(8):854-8. PMID: 7583140.
    Citations: 42     Fields:    Translation:AnimalsCells
  129. Wefes I, Mastrandrea LD, Haldeman M, Koury ST, Tamburlin J, Pickart CM, Finley D. Induction of ubiquitin-conjugating enzymes during terminal erythroid differentiation. Proc Natl Acad Sci U S A. 1995 May 23; 92(11):4982-6. PMID: 7761435.
    Citations: 18     Fields:    Translation:AnimalsCells
  130. Spence J, Sadis S, Haas AL, Finley D. A ubiquitin mutant with specific defects in DNA repair and multiubiquitination. Mol Cell Biol. 1995 Mar; 15(3):1265-73. PMID: 7862120.
    Citations: 171     Fields:    Translation:AnimalsCells
  131. Yaglom J, Linskens MH, Sadis S, Rubin DM, Futcher B, Finley D. p34Cdc28-mediated control of Cln3 cyclin degradation. Mol Cell Biol. 1995 Feb; 15(2):731-41. PMID: 7823941.
    Citations: 106     Fields:    Translation:AnimalsCells
  132. Finley D, Sadis S, Monia BP, Boucher P, Ecker DJ, Crooke ST, Chau V. Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant. Mol Cell Biol. 1994 Aug; 14(8):5501-9. PMID: 8035826.
    Citations: 122     Fields:    Translation:AnimalsCells
  133. Driscoll J, Brown MG, Finley D, Monaco JJ. MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature. 1993 Sep 16; 365(6443):262-4. PMID: 8371781.
    Citations: 107     Fields:    Translation:HumansCells
  134. Driscoll J, Finley D. A controlled breakdown: antigen processing and the turnover of viral proteins. Cell. 1992 Mar 06; 68(5):823-5. PMID: 1312390.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  135. Park EC, Finley D, Szostak JW. A strategy for the generation of conditional mutations by protein destabilization. Proc Natl Acad Sci U S A. 1992 Feb 15; 89(4):1249-52. PMID: 1311090.
    Citations: 27     Fields:    Translation:AnimalsCells
  136. Finley D, Chau V. Ubiquitination. Annu Rev Cell Biol. 1991; 7:25-69. PMID: 1667082.
    Citations: 124     Fields:    Translation:HumansAnimalsCells
  137. Finley D, Bartel B, Varshavsky A. The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis. Nature. 1989 Mar 30; 338(6214):394-401. PMID: 2538753.
    Citations: 211     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.