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James F. Markmann, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI146248 (MARKMANN, JAMES F) Feb 1, 2020 - Jan 31, 2025
    NIH/NIAID
    Liver Xenotransplantation using CRISPR-modified Porcine Organs
    Role: Principal Investigator
  2. R01DK107875 (MARKMANN, JAMES F) Jul 10, 2016 - Apr 30, 2021
    NIH/NIDDK
    Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion
    Role: Principal Investigator
  3. R01AI057851 (MARKMANN, JAMES F) Dec 1, 2003 - Nov 30, 2022
    NIH/NIAID
    Mechanisms of B Cell-Dependent Transplantation Tolerance
    Role: Principal Investigator
  4. R56AI057851 (MARKMANN, JAMES F) Dec 1, 2003 - Feb 29, 2012
    NIH/NIAID
    Mechanisms of B Cell-Dependent Transplantation Tolerance
    Role: Principal Investigator
  5. R56AI048820 (MARKMANN, JAMES F) Dec 1, 2000 - Aug 31, 2011
    NIH/NIAID
    Regulation and Counter-Regulation in Transplantation
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyó J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheffold A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK. Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials. Lancet. 2020 05 23; 395(10237):1627-1639. PMID: 32446407.
    Citations:    
  2. de Vries RJ, Tessier SN, Banik PD, Nagpal S, Cronin SEJ, Ozer S, Hafiz EOA, van Gulik TM, Yarmush ML, Markmann JF, Toner M, Yeh H, Uygun K. Subzero non-frozen preservation of human livers in the supercooled state. Nat Protoc. 2020 Jun; 15(6):2024-2040. PMID: 32433625.
    Citations:    
  3. DiNorcia J, Florman SS, Haydel B, Tabrizian P, Ruiz RM, Klintmalm GB, Senguttuvan S, Lee DD, Taner CB, Verna EC, Halazun KJ, Hoteit M, Levine MH, Chapman WC, Vachharajani N, Aucejo F, Nguyen MH, Melcher ML, Tevar AD, Humar A, Mobley C, Ghobrial M, Nydam TL, Amundsen B, Markmann JF, Berumen J, Hemming AW, Langnas AN, Carney CA, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Markovic D, Busuttil RW, Agopian VG. Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium. Ann Surg. 2020 04; 271(4):616-624. PMID: 30870180.
    Citations:    
  4. Kardashian A, Florman SS, Haydel B, Ruiz RM, Klintmalm GB, Lee DD, Taner CB, Aucejo F, Tevar AD, Humar A, Verna EC, Halazun KJ, Chapman WC, Vachharajani N, Hoteit M, Levine MH, Nguyen MH, Melcher ML, Langnas AN, Carney CA, Mobley C, Ghobrial M, Amundsen B, Markmann JF, Sudan DL, Jones CM, Berumen J, Hemming AW, Hong JC, Kim J, Zimmerman MA, Nydam TL, Rana A, Kueht ML, Fishbein TM, Markovic D, Busuttil RW, Agopian VG. Liver Transplantation Outcomes in a U.S. Multicenter Cohort of 789 Patients with Hepatocellular Carcinoma Presenting Beyond Milan Criteria. Hepatology. 2020 Mar 02. PMID: 32124453.
    Citations:    
  5. de Vries RJ, Pendexter CA, Cronin SEJ, Marques B, Hafiz EOA, Muzikansky A, van Gulik TM, Markmann JF, Stott SL, Yeh H, Toner M, Uygun K, Tessier SN. Cell release during perfusion reflects cold ischemic injury in rat livers. Sci Rep. 2020 Jan 24; 10(1):1102. PMID: 31980677.
    Citations:    
  6. Raigani S, Karimian N, Huang V, Zhang AM, Beijert I, Geerts S, Nagpal S, Hafiz EOA, Fontan FM, Aburawi MM, Mahboub P, Markmann JF, Porte RJ, Uygun K, Yarmush M, Yeh H. Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies. PLoS One. 2020; 15(1):e0228011. PMID: 31978172.
    Citations:    
  7. Huang V, Karimian N, Detelich D, Raigani S, Geerts S, Beijert I, Fontan FM, Aburawi MM, Ozer S, Banik P, Lin F, Karabacak M, Hafiz EOA, Porte RJ, Uygun K, Markmann JF, Yeh H. Split-Liver Ex Situ Machine Perfusion: A Novel Technique for Studying Organ Preservation and Therapeutic Interventions. J Clin Med. 2020 Jan 18; 9(1). PMID: 31963739.
    Citations:    
  8. Kimura S, Rickert CG, Kojima L, Aburawi M, Tanimine N, Fontan F, Deng K, Tector H, Mi Lee K, Yeh H, Markmann JF. Regulatory B cells require antigen recognition for effective allograft tolerance induction. Am J Transplant. 2020 04; 20(4):977-987. PMID: 31823520.
    Citations:    
  9. de Vries RJ, Tessier SN, Banik PD, Nagpal S, Cronin SEJ, Ozer S, Hafiz EOA, van Gulik TM, Yarmush ML, Markmann JF, Toner M, Yeh H, Uygun K. Supercooling extends preservation time of human livers. Nat Biotechnol. 2019 10; 37(10):1131-1136. PMID: 31501557.
    Citations:    
  10. Firl DJ, Sasaki K, Agopian VG, Gorgen A, Kimura S, Dumronggittigule W, McVey JC, Iesari S, Mennini G, Vitale A, Finkenstedt A, Onali S, Hoppe-Lotichius M, Vennarecci G, Manzia TM, Nicolini D, Avolio AW, Agnes S, Vivarelli M, Tisone G, Ettorre GM, Otto G, Tsochatzis E, Rossi M, Viveiros A, Cillo U, Markmann JF, Ikegami T, Kaido T, Lai Q, Sapisochin G, Lerut J, Aucejo FN. Charting the Path Forward for Risk Prediction in Liver Transplant for Hepatocellular Carcinoma: International Validation of HALTHCC Among 4,089 Patients. Hepatology. 2020 Feb; 71(2):569-582. PMID: 31243778.
    Citations:    
  11. Fu Q, Yang F, Liao M, Feeney NJ, Deng K, Serifis N, Wei L, Yang H, Chen K, Deng S, Markmann JF. Rap GTPase Interactor: A Potential Marker for Cancer Prognosis Following Kidney Transplantation. Front Oncol. 2019; 9:737. PMID: 31448237.
    Citations:    
  12. Mahboub P, Aburawi M, Karimian N, Lin F, Karabacak M, Fontan F, Tessier SN, Markmann J, Yeh H, Uygun K. The efficacy of HBOC-201 in ex situ gradual rewarming kidney perfusion in a rat model. Artif Organs. 2020 Jan; 44(1):81-90. PMID: 31368159.
    Citations:    
  13. Rickert CG, Markmann JF. Current state of organ transplant tolerance. Curr Opin Organ Transplant. 2019 08; 24(4):441-450. PMID: 31169530.
    Citations:    
  14. Bethea ED, Gaj K, Gustafson JL, Axtell A, Lebeis T, Schoenike M, Turvey K, Coglianese E, Thomas S, Newton-Cheh C, Ibrahim N, Carlson W, Ho JE, Shah R, Nayor M, Gift T, Shao S, Dugal A, Markmann J, Elias N, Yeh H, Andersson K, Pratt D, Bhan I, Safa K, Fishman J, Kotton C, Myoung P, Villavicencio MA, D'Alessandro D, Chung RT, Lewis GD. Pre-emptive pangenotypic direct acting antiviral therapy in donor HCV-positive to recipient HCV-negative heart transplantation: an open-label study. Lancet Gastroenterol Hepatol. 2019 10; 4(10):771-780. PMID: 31353243.
    Citations:    
  15. Fu Q, Liao M, Feng C, Tang J, Liao R, Wei L, Yang H, Markmann JF, Chen K, Deng S. Profiling of mRNA of interstitial fibrosis and tubular atrophy with subclinical inflammation in recipients after kidney transplantation. Aging (Albany NY). 2019 07 25; 11(14):5215-5231. PMID: 31343413.
    Citations:    
  16. Raigani S, Markmann JF, Yeh H. Rehabilitation of Discarded Steatotic Livers Using Ex Situ Normothermic Machine Perfusion: A Future Source of Livers for Transplantation. Liver Transpl. 2019 07; 25(7):991-992. PMID: 31077626.
    Citations:    
  17. Tanimine N, Germana SK, Fan M, Hippen K, Blazar BR, Markmann JF, Turka LA, Priyadharshini B. Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets. PLoS One. 2019; 14(6):e0217761. PMID: 31170216.
    Citations:    
  18. Aburawi MM, Fontan FM, Karimian N, Eymard C, Cronin S, Pendexter C, Nagpal S, Banik P, Ozer S, Mahboub P, Delmonico FL, Yeh H, Uygun K, Markmann JF. Synthetic hemoglobin-based oxygen carriers are an acceptable alternative for packed red blood cells in normothermic kidney perfusion. Am J Transplant. 2019 10; 19(10):2814-2824. PMID: 30938927.
    Citations:    
  19. Sremac M, Lei J, Penson MFE, Schuetz C, Lakey JRT, Papas KK, Varde PS, Hering B, de Vos P, Brauns T, Markmann J, Poznansky MC. Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates. Transplant Direct. 2019 May; 5(5):e447. PMID: 31165082.
    Citations:    
  20. Jones CN, Ellett F, Robertson AL, Forrest KM, Judice K, Balkovec JM, Springer M, Markmann JF, Vyas JM, Warren HS, Irimia D. Bifunctional Small Molecules Enhance Neutrophil Activities Against Aspergillus fumigatus in vivo and in vitro. Front Immunol. 2019; 10:644. PMID: 31024528.
    Citations:    
  21. Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC. Alginate-microencapsulation of human stem cell-derived ß cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression. Am J Transplant. 2019 07; 19(7):1930-1940. PMID: 30748094.
    Citations:    
  22. Panda N, Brackett D, Eymard C, Kawai T, Markmann J, Kotton CN, Andersson K, Yeh H. Liver Transplantation for Recurrent Cholangitis From Von Meyenburg Complexes. Transplant Direct. 2019 Mar; 5(3):e428. PMID: 30882033.
    Citations:    
  23. Martins PN, Berendsen TA, Yeh H, Bruinsma BG, Izamis ML, Op den Dries S, Gillooly AR, Porte R, Yarmush ML, Uygun K, Markmann JF. Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts. Transplantation. 2019 02; 103(2):363-370. PMID: 30422952.
    Citations:    Fields:    
  24. Navarro-Alvarez N, Machaidze Z, Schuetz C, Zhu A, Liu WH, Shah JA, Vagefi PA, Elias N, Buhler L, Sachs DH, Markmann JF, Yeh H. Xenogeneic Heterotopic Auxiliary Liver transplantation (XHALT) promotes native liver regeneration in a Post-Hepatectomy Liver failure model. PLoS One. 2018; 13(11):e0207272. PMID: 30462716.
    Citations:    Fields:    
  25. Eymard C, Markmann J. Normothermic ex vivo liver perfusion: platform for liver graft assessment and therapeutic modification. Organogenesis. 2018; 14(4):169-171. PMID: 30289350.
    Citations:    Fields:    
  26. Firl DJ, Kimura S, McVey J, Hashimoto K, Yeh H, Miller CM, Markmann JF, Sasaki K, Aucejo FN. Reframing the approach to patients with hepatocellular carcinoma: Longitudinal assessment with hazard associated with liver transplantation for HCC (HALTHCC) improves ablate and wait strategy. Hepatology. 2018 10; 68(4):1448-1458. PMID: 29604231.
    Citations: 1     Fields:    
  27. Michelakos T, Xourafas D, Qadan M, Pieretti-Vanmarcke R, Cai L, Patel MS, Adler JT, Fontan F, Basit U, Vagefi PA, Elias N, Tanabe KK, Berger D, Yeh H, Markmann JF, Chang DC, Ferrone CR. Hepatocellular Carcinoma in Transplantable Child-Pugh A Cirrhotics: Should Cost Affect Resection vs Transplantation? J Gastrointest Surg. 2019 06; 23(6):1135-1142. PMID: 30218342.
    Citations:    Fields:    
  28. Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S. Defining Outcomes for ß-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop. Transplantation. 2018 09; 102(9):1479-1486. PMID: 29528967.
    Citations: 1     Fields:    
  29. Martins PN, Brüggenwirth IMA, McDaid J, Hertl M, Kawai T, Elias N, Chung RT, Markmann JF. Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant. Exp Clin Transplant. 2018 Aug 17. PMID: 30119616.
    Citations:    Fields:    
  30. Roushan M, Jorfi M, Mishra A, Wong KHK, Jorgensen J, Ell E, Markmann JF, Lee J, Irimia D. Trapped Chromatin Fibers Damage Flowing Red Blood Cells. Adv Biosyst. 2018 Oct; 2(10). PMID: 31223642.
    Citations:    
  31. Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. Transplantation. 2018 08; 102(8):1223-1229. PMID: 29781950.
    Citations:    Fields:    
  32. Detelich D, Markmann JF. Normothermic liver preservation, current status and future directions. Curr Opin Organ Transplant. 2018 06; 23(3):347-352. PMID: 29629996.
    Citations:    Fields:    
  33. Beijert I, Mert S, Huang V, Karimian N, Geerts S, Hafiz EOA, Markmann JF, Yeh H, Porte RJ, Uygun K. Endothelial Dysfunction in Steatotic Human Donor Livers: A Pilot Study of the Underlying Mechanism During Subnormothermic Machine Perfusion. Transplant Direct. 2018 May; 4(5):e345. PMID: 29796416.
    Citations: 1     
  34. Markmann JF. Relaxing liver ischemia reperfusion injury down 1 notch. Am J Transplant. 2018 07; 18(7):1587-1588. PMID: 29569343.
    Citations:    Fields:    
  35. Detelich D, Markmann JF. The dawn of liver perfusion machines. Curr Opin Organ Transplant. 2018 04; 23(2):151-161. PMID: 29324518.
    Citations:    Fields:    
  36. Markmann JF. Commentary on Nurse Telephonic Triage Service for After-hour Patient Calls in Neurosurgery. Ann Surg. 2018 04; 267(4):e69. PMID: 29401108.
    Citations:    Fields:    
  37. Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S. Defining outcomes for ß-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop. Transpl Int. 2018 04; 31(4):343-352. PMID: 29453879.
    Citations: 1     Fields:    Translation:Humans
  38. Okulov IV, Okulov AV, Soldatov IV, Luthringer B, Willumeit-Römer R, Wada T, Kato H, Weissmüller J, Markmann J. Open porous dealloying-based biomaterials as a novel biomaterial platform. Mater Sci Eng C Mater Biol Appl. 2018 Jul 01; 88:95-103. PMID: 29636143.
    Citations:    Fields:    Translation:HumansCells
  39. Piemonti L, de Koning EJP, Berney T, Odorico JS, Markmann JF, Stock PG, Rickels MR. Defining outcomes for beta cell replacement therapy: a work in progress. Diabetologia. 2018 06; 61(6):1273-1276. PMID: 29511779.
    Citations: 2     Fields:    Translation:Humans
  40. Rezanejad H, Ouziel-Yahalom L, Keyzer CA, Sullivan BA, Hollister-Lock J, Li WC, Guo L, Deng S, Lei J, Markmann J, Bonner-Weir S. Heterogeneity of SOX9 and HNF1ß in Pancreatic Ducts Is Dynamic. Stem Cell Reports. 2018 03 13; 10(3):725-738. PMID: 29478894.
    Citations:    Fields:    
  41. Cao B, Adler JT, Bababekov YJ, Markmann JF, Chang DC, Yeh H. Pediatric kidney transplantation and mortality: Distance to transplant center matters. Pediatr Transplant. 2018 03; 22(2). PMID: 29316061.
    Citations: 1     Fields:    Translation:Humans
  42. Ben Nasr M, Tezza S, D'Addio F, Mameli C, Usuelli V, Maestroni A, Corradi D, Belletti S, Albarello L, Becchi G, Fadini GP, Schuetz C, Markmann J, Wasserfall C, Zon L, Zuccotti GV, Fiorina P. PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. Sci Transl Med. 2017 Nov 15; 9(416). PMID: 29141886.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  43. Avruch JH, Bruinsma BG, Weeder PD, Sridharan GV, Porte RJ, Yeh H, Markmann JF, Uygun K. A novel model for ex situ reperfusion of the human liver following subnormothermic machine perfusion. Technology (Singap World Sci). 2017 Dec; 5(4):196-200. PMID: 31106253.
    Citations:    
  44. Agopian VG, Harlander-Locke MP, Ruiz RM, Klintmalm GB, Senguttuvan S, Florman SS, Haydel B, Hoteit M, Levine MH, Lee DD, Taner CB, Verna EC, Halazun KJ, Abdelmessih R, Tevar AD, Humar A, Aucejo F, Chapman WC, Vachharajani N, Nguyen MH, Melcher ML, Nydam TL, Mobley C, Ghobrial RM, Amundsen B, Markmann JF, Langnas AN, Carney CA, Berumen J, Hemming AW, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Busuttil RW. Impact of Pretransplant Bridging Locoregional Therapy for Patients With Hepatocellular Carcinoma Within Milan Criteria Undergoing Liver Transplantation: Analysis of 3601 Patients From the US Multicenter HCC Transplant Consortium. Ann Surg. 2017 09; 266(3):525-535. PMID: 28654545.
    Citations: 12     Fields:    Translation:Humans
  45. Bruinsma BG, Avruch JH, Sridharan GV, Weeder PD, Jacobs ML, Crisalli K, Amundsen B, Porte RJ, Markmann JF, Uygun K, Yeh H. Peritransplant Energy Changes and Their Correlation to Outcome After Human Liver Transplantation. Transplantation. 2017 07; 101(7):1637-1644. PMID: 28230641.
    Citations: 1     Fields:    Translation:Humans
  46. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428. Diabetes. 2017 09; 66(9):2531. PMID: 28663189.
    Citations: 1     Fields:    
  47. Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden ES, Eidbo E, Lee WPA, Pomahac B, Brandacher G, Weinstock DM, Elliott G, Nelson D, Acker JP, Uygun K, Schmalz B, Weegman BP, Tocchio A, Fahy GM, Storey KB, Rubinsky B, Bischof J, Elliott JAW, Woodruff TK, Morris GJ, Demirci U, Brockbank KGM, Woods EJ, Ben RN, Baust JG, Gao D, Fuller B, Rabin Y, Kravitz DC, Taylor MJ, Toner M. The promise of organ and tissue preservation to transform medicine. Nat Biotechnol. 2017 06 07; 35(6):530-542. PMID: 28591112.
    Citations: 7     Fields:    Translation:Humans
  48. Shah JA, Patel MS, Elias N, Navarro-Alvarez N, Rosales I, Wilkinson RA, Louras NJ, Hertl M, Fishman JA, Colvin RB, Cosimi AB, Markmann JF, Sachs DH, Vagefi PA. Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade. Am J Transplant. 2017 Aug; 17(8):2178-2185. PMID: 28489305.
    Citations: 6     Fields:    Translation:Animals
  49. Ansite J, Balamurugan AN, Barbaro B, Battle J, Brandhorst D, Cano J, Chen X, Deng S, Feddersen D, Friberg A, Gilmore T, Goldstein JS, Holbrook E, Khan A, Kin T, Lei J, Linetsky E, Liu C, Luo X, McElvaney K, Min Z, Moreno J, O'Gorman D, Papas KK, Putz G, Ricordi C, Szot G, Templeton T, Wang L, Wilhelm JJ, Willits J, Wilson T, Zhang X, Avila J, Begley B, Cano J, Carpentier S, Holbrook E, Hutchinson J, Larsen CP, Moreno J, Sears M, Turgeon NA, Webster D, Deng S, Lei J, Markmann JF, Bridges ND, Czarniecki CW, Goldstein JS, Putz G, Templeton T, Wilson T, Eggerman TL, Al-Saden P, Battle J, Chen X, Hecyk A, Kissler H, Luo X, Molitch M, Monson N, Stuart E, Wallia A, Wang L, Wang S, Zhang X, Bigam D, Campbell P, Dinyari P, Kin T, Kneteman N, Lyon J, Malcolm A, O'Gorman D, Onderka C, Owen R, Pawlick R, Richer B, Rosichuk S, Sarman D, Schroeder A, Senior PA, Shapiro AMJ, Toth L, Toth V, Zhai W, Johnson K, McElroy J, Posselt AM, Ramos M, Rojas T, Stock PG, Szot G, Barbaro B, Martellotto J, Oberholzer J, Qi M, Wang Y, Bayman L, Chaloner K, Clarke W, Dillon JS, Diltz C, Doelle GC, Ecklund D, Feddersen D, Foster E, Hunsicker LG, Jasperson C, Lafontant DE, McElvaney K, Neill-Hudson T, Nollen D, Qidwai J, Riss H, Schwieger T, Willits J, Yankey J, Alejandro R, Corrales AC, Faradji R, Froud T, Garcia AA, Herrada E, Ichii H, Inverardi L, Kenyon N, Khan A, Linetsky E, Montelongo J, Peixoto E, Peterson K, Ricordi C, Szust J, Wang X, Abdulla MH, Ansite J, Balamurugan AN, Bellin MD, Brandenburg M, Gilmore T, Harmon JV, Hering BJ, Kandaswamy R, Loganathan G, Mueller K, Papas KK, Pedersen J, Wilhelm JJ, Witson J, Dalton-Bakes C, Fu H, Kamoun M, Kearns J, Li Y, Liu C, Luning-Prak E, Luo Y, Markmann E, Min Z, Naji A, Palanjian M, Rickels M, Shlansky-Goldberg R, Vivek K, Ziaie AS, Fernandez L, Kaufman DB, Zitur L, Brandhorst D, Friberg A, Korsgren O. Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide. CellR4 Repair Replace Regen Reprogram. 2017; 5(3). PMID: 30613755.
    Citations:    
  50. Goldberg DS, Karp SJ, McCauley ME, Markmann JF, Croome KP, Taner CB, Heimbach JK, Leise MD, Fryer JP, Bohorquez HE, Cohen AJ, Gilroy RK, Kumer SC, Foley DP, Karim AS, Hernandez-Alejandro R, Levstik MA, Abt PL. Interpreting Outcomes in DCDD Liver Transplantation: First Report of the Multicenter IDOL Consortium. Transplantation. 2017 05; 101(5):1067-1073. PMID: 28114173.
    Citations: 1     Fields:    Translation:Humans
  51. Schuetz C, Lee KM, Scott R, Kojima L, Washburn L, Liu L, Liu WH, Tector H, Lei J, Yeh H, Kim JI, Markmann JF. Regulatory B Cell-Dependent Islet Transplant Tolerance Is Also Natural Killer Cell Dependent. Am J Transplant. 2017 Jun; 17(6):1656-1662. PMID: 28296255.
    Citations: 2     Fields:    Translation:AnimalsCells
  52. Villani V, Gupta N, Elias N, Vagefi PA, Markmann JF, Paul E, Traum AZ, Yeh H. Bilateral native nephrectomy reduces systemic oxalate level after combined liver-kidney transplant: A case report. Pediatr Transplant. 2017 May; 21(3). PMID: 28261895.
    Citations: 1     Fields:    Translation:Humans
  53. Machaidze Z, Yeh H, Wei L, Schuetz C, Carvello M, Sgroi A, Smith RN, Schuurman HJ, Sachs DH, Morel P, Markmann JF, Bühler LH. Testing of microencapsulated porcine hepatocytes in a new model of fulminant liver failure in baboons. Xenotransplantation. 2017 05; 24(3). PMID: 28261903.
    Citations: 2     Fields:    Translation:AnimalsCells
  54. Okulov IV, Weissmüller J, Markmann J. Dealloying-based interpenetrating-phase nanocomposites matching the elastic behavior of human bone. Sci Rep. 2017 02 02; 7(1):20. PMID: 28154414.
    Citations: 1     Fields:    
  55. Markmann JF, Yeh H. The Beginnings of a Transplant Revolution. Ann Surg. 2017 01; 265(1):e3. PMID: 27464619.
    Citations:    Fields:    
  56. Adler JT, Bababekov YJ, Markmann JF, Chang DC, Yeh H. Distance is associated with mortality on the waitlist in pediatric liver transplantation. Pediatr Transplant. 2017 Mar; 21(2). PMID: 27804189.
    Citations:    Fields:    Translation:Humans
  57. Shah JA, Patel MS, Kratz JR, Markmann JF, Vagefi PA.  High risk, high reward: An analysis of outcomes for candidates awaiting hepatic re-transplantation. Ann Hepatol. 2016 Nov-Dec 2016; 15(6):888-894. PMID: 27740522.
    Citations:    Fields:    Translation:Humans
  58. Shah JA, Patel MS, Kratz JR, Markmann JF, Vagefi PA. High risk, high reward: An analysis of outcomes for candidates awaiting hepatic re-transplantation. Ann Hepatol. 2016 Nov - Dec; 15(6):888-894. PMID: 31208661.
    Citations:    
  59. Patel MS, Mohebali J, Shah JA, Markmann JF, Vagefi PA. Readmission following liver transplantation: an unwanted occurrence but an opportunity to act. HPB (Oxford). 2016 11; 18(11):936-942. PMID: 27642080.
    Citations: 1     Fields:    Translation:Humans
  60. Oura T, Hotta K, Lei J, Markmann J, Rosales I, Dehnadi A, Kawai K, Ndishabandi D, Smith RN, Cosimi AB, Kawai T. Immunosuppression With CD40 Costimulatory Blockade Plus Rapamycin for Simultaneous Islet-Kidney Transplantation in Nonhuman Primates. Am J Transplant. 2017 03; 17(3):646-656. PMID: 27501203.
    Citations: 4     Fields:    Translation:Animals
  61. Markmann JF. Signatures of Tolerance or Immunosuppression? Am J Transplant. 2016 12; 16(12):3320-3321. PMID: 27467554.
    Citations:    Fields:    
  62. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM, Chen X. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes. 2016 11; 65(11):3418-3428. PMID: 27465220.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  63. Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, Abdi R, Uehara M, Kim JI, Markmann JF, Tocco G, Benichou G. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Sci Immunol. 2016 Jul 14; 1(1). PMID: 27942611.
    Citations: 3     Fields:    
  64. Adler JT, Markmann JF, Yeh H. Renal allograft thrombosis after living donor transplantation: risk factors and obstacles to retransplantation. Clin Transplant. 2016 08; 30(8):864-71. PMID: 27101358.
    Citations: 2     Fields:    Translation:Humans
  65. Markmann JF, Bartlett ST, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, O'Connell PJ, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Khovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of ß-Cell Replacement. Transplantation. 2016 Jul; 100(7):e25-31. PMID: 27082827.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  66. Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, Abdi R, Uehara M, Kim JI, Markmann JF, Tocco G, Benichou G. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Sci Immunol. 2016 Jul 14; 1(1):aaf8759. PMID: 28783676.
    Citations: 11     Fields:    
  67. Karangwa SA, Dutkowski P, Fontes P, Friend PJ, Guarrera JV, Markmann JF, Mergental H, Minor T, Quintini C, Selzner M, Uygun K, Watson CJ, Porte RJ. Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines. Am J Transplant. 2016 10; 16(10):2932-2942. PMID: 27129409.
    Citations: 5     Fields:    Translation:Humans
  68. Madariaga ML, Spencer PJ, Shanmugarajah K, Crisalli KA, Chang DC, Markmann JF, Elias N, Cosimi AB, Sachs DH, Kawai T. Effect of tolerance versus chronic immunosuppression protocols on the quality of life of kidney transplant recipients. JCI Insight. 2016 Jun 02; 1(8). PMID: 27336062.
    Citations: 5     Fields:    
  69. Adler JT, Yeh H, Markmann JF, Axelrod DA. Is Donor Service Area Market Competition Associated With Organ Procurement Organization Performance? Transplantation. 2016 06; 100(6):1349-55. PMID: 26516674.
    Citations:    Fields:    Translation:Humans
  70. Shah JA, Navarro-Alvarez N, DeFazio M, Rosales IA, Elias N, Yeh H, Colvin RB, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. A Bridge to Somewhere: 25-day Survival After Pig-to-Baboon Liver Xenotransplantation. Ann Surg. 2016 06; 263(6):1069-71. PMID: 26825261.
    Citations: 9     Fields:    Translation:Animals
  71. Schuetz C, Markmann JF. Islet cell transplant: Update on current clinical trials. Curr Transplant Rep. 2016 Sep; 3(3):254-263. PMID: 28451515.
    Citations: 2     
  72. Hering BJ, Clarke WR, Bridges ND, Eggerman TL, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Markmann JF, Naji A, Oberholzer J, Posselt AM, Rickels MR, Ricordi C, Robien MA, Senior PA, Shapiro AM, Stock PG, Turgeon NA. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia. Diabetes Care. 2016 Jul; 39(7):1230-40. PMID: 27208344.
    Citations: 50     Fields:    Translation:HumansCTClinical Trials
  73. Xu Y, Navarro-Alvarez N, Yang C, Markmann JF, Dong J, Yeh H. A reliable scoring system after major liver resection in mice. J Surg Res. 2016 07; 204(1):75-82. PMID: 27451871.
    Citations:    Fields:    Translation:Animals
  74. Adler JT, Hyder JA, Markmann JF, Axelrod DA, Yeh H. Socioeconomic gradients between locally transplanted and exported liver donors and recipients. Liver Transpl. 2016 Apr; 22(4):557-8. PMID: 26845498.
    Citations:    Fields:    Translation:Humans
  75. Guinan EC, Cole GA, Wylie WH, Kelner RH, Janec KJ, Yuan H, Oppatt J, Brennan LL, Turka LA, Markmann J. Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation. Am J Transplant. 2016 07; 16(7):2187-95. PMID: 26790369.
    Citations: 4     Fields:    Translation:HumansCells
  76. Bruinsma BG, Sridharan GV, Weeder PD, Avruch JH, Saeidi N, Özer S, Geerts S, Porte RJ, Heger M, van Gulik TM, Martins PN, Markmann JF, Yeh H, Uygun K. Metabolic profiling during ex vivo machine perfusion of the human liver. Sci Rep. 2016 Mar 03; 6:22415. PMID: 26935866.
    Citations: 11     Fields:    Translation:Humans
  77. Adler JT, Yeh H, Markmann JF, Nguyen LL. Temporal Analysis of Market Competition and Density in Renal Transplantation Volume and Outcome. Transplantation. 2016 Mar; 100(3):670-7. PMID: 26574684.
    Citations:    Fields:    Translation:Humans
  78. Wang LJ, Kin T, O'Gorman D, Shapiro AMJ, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, Chen T, Lian M, Markmann JF, Alvarez A, Linetsky E, Ricordi C, Balamurugan AN, Loganathan G, Wilhelm JJ, Hering BJ, Bottino R, Trucco M, Liu C, Min Z, Li Y, Naji A, Fernandez LA, Ziemelis M, Danobeitia JS, Millis JM, Witkowski P. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation. Cell Transplant. 2016; 25(8):1515-1523. PMID: 26922947.
    Citations: 1     Fields:    Translation:Humans
  79. Sanchez-Fueyo A, Markmann JF. Immune Exhaustion and Transplantation. Am J Transplant. 2016 07; 16(7):1953-7. PMID: 26729653.
    Citations: 5     Fields:    Translation:Humans
  80. Navarro-Alvarez N, Shah JA, Zhu A, Ligocka J, Yeh H, Elias N, Rosales I, Colvin R, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. The Effects of Exogenous Administration of Human Coagulation Factors Following Pig-to-Baboon Liver Xenotransplantation. Am J Transplant. 2016 06; 16(6):1715-1725. PMID: 26613235.
    Citations: 7     Fields:    Translation:HumansAnimals
  81. Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, O'Connell P, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Kovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Report from IPITA-TTS Opinion Leaders Meeting on the Future of ß-Cell Replacement. Transplantation. 2016 Feb; 100 Suppl 2:S1-44. PMID: 26840096.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  82. Heher E, Markmann JF. The Clearer BENEFITS of Belatacept. N Engl J Med. 2016 Jan 28; 374(4):388-9. PMID: 26816017.
    Citations: 3     Fields:    Translation:Humans
  83. Fong ZV, Patel MS, Yeh H, Markmann JF, Vagefi PA. Liver transplantation utilizing a severely fractured graft: every organ counts. Ann Hepatol. 2016 Jan-Feb; 15(1):131-4. PMID: 26626650.
    Citations:    Fields:    Translation:Humans
  84. Ven Fong Z, Patel MS, Yeh H, Markmann JF, Vagefi PA. Liver transplantation utilizing a severely fractured graft: every organ counts. Ann Hepatol. 2016 Jan - Feb; 15(1):131-134. PMID: 31320158.
    Citations:    
  85. Markmann JF. Isolated Pancreatic Islet Transplantation: A Coming of Age. Am J Transplant. 2016 Feb; 16(2):381-2. PMID: 26595885.
    Citations:    Fields:    Translation:Humans
  86. Jain NG, Wong EA, Aranyosi AJ, Boneschansker L, Markmann JF, Briscoe DM, Irimia D. Microfluidic mazes to characterize T-cell exploration patterns following activation in vitro. Integr Biol (Camb). 2015 Nov; 7(11):1423-31. PMID: 26325525.
    Citations: 5