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James F. Markmann, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK107875 (MARKMANN, JAMES F) Jul 10, 2016 - Apr 30, 2021
    NIH/NIDDK
    Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion
    Role: Principal Investigator
  2. R01AI057851 (MARKMANN, JAMES F) Dec 1, 2003 - Nov 30, 2022
    NIH/NIAID
    Mechanisms of B Cell-Dependent Transplantation Tolerance
    Role: Principal Investigator
  3. R56AI057851 (MARKMANN, JAMES F) Dec 1, 2003 - Feb 29, 2012
    NIH/NIAID
    Mechanisms of B Cell-Dependent Transplantation Tolerance
    Role: Principal Investigator
  4. R56AI048820 (MARKMANN, JAMES F) Dec 1, 2000 - Aug 31, 2011
    NIH/NIAID
    Regulation and Counter-Regulation in Transplantation
    Role: Principal Investigator
  5. R01AI048820 (MARKMANN, JAMES F) Dec 1, 2000 - Apr 30, 2010
    NIH/NIAID
    Regulatory T cells in transplantation tolerance
    Role: Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tanimine N, Germana SK, Fan M, Hippen K, Blazar BR, Markmann JF, Turka LA, Priyadharshini B. Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets. PLoS One. 2019; 14(6):e0217761. PMID: 31170216.
    Citations:    
  2. Rickert CG, Markmann JF. Current state of organ transplant tolerance. Curr Opin Organ Transplant. 2019 Jun 04. PMID: 31169530.
    Citations:    
  3. Raigani S, Markmann JF, Yeh H. Rehabilitation of Discarded Steatotic Livers using Ex Situ Normothermic Machine Perfusion: A Future Source of Livers for Transplantation. Liver Transpl. 2019 May 11. PMID: 31077626.
    Citations:    
  4. Sremac M, Lei J, Penson MFE, Schuetz C, Lakey JRT, Papas KK, Varde PS, de Vos P, Brauns T, Markmann J, Poznansky MC, Hering B. Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates. Transplant Direct. 2019 May; 5(5):e447. PMID: 31165082.
    Citations:    
  5. Jones CN, Ellett F, Robertson AL, Forrest KM, Judice K, Balkovec JM, Springer M, Markmann JF, Vyas JM, Warren HS, Irimia D. Bifunctional Small Molecules Enhance Neutrophil Activities Against Aspergillus fumigatus in vivo and in vitro. Front Immunol. 2019; 10:644. PMID: 31024528.
    Citations:    
  6. Aburawi MM, Fontan FM, Karimian N, Eymard C, Cronin S, Pendexter C, Nagpal S, Banik P, Ozer S, Mahboub P, Delmonico FL, Yeh H, Uygun K, Markmann JF. Synthetic hemoglobin-based oxygen carriers are an acceptable alternative for packed red blood cells in normothermic kidney perfusion. Am J Transplant. 2019 Apr 02. PMID: 30938927.
    Citations:    
  7. DiNorcia J, Florman SS, Haydel B, Tabrizian P, Ruiz RM, Klintmalm GB, Senguttuvan S, Lee DD, Taner CB, Verna EC, Halazun KJ, Hoteit M, Levine MH, Chapman WC, Vachharajani N, Aucejo F, Nguyen MH, Melcher ML, Tevar AD, Humar A, Mobley C, Ghobrial M, Nydam TL, Amundsen B, Markmann JF, Berumen J, Hemming AW, Langnas AN, Carney CA, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Markovic D, Busuttil RW, Agopian VG. Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium. Ann Surg. 2019 Mar 05. PMID: 30870180.
    Citations:    
  8. Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC. Alginate-microencapsulation of human stem cell-derived ß cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression. Am J Transplant. 2019 Feb 12. PMID: 30748094.
    Citations:    
  9. Panda N, Brackett D, Eymard C, Kawai T, Markmann J, Kotton CN, Andersson K, Yeh H. Liver Transplantation for Recurrent Cholangitis From Von Meyenburg Complexes. Transplant Direct. 2019 Mar; 5(3):e428. PMID: 30882033.
    Citations:    
  10. Martins PN, Berendsen TA, Yeh H, Bruinsma BG, Izamis ML, Op den Dries S, Gillooly AR, Porte R, Yarmush ML, Uygun K, Markmann JF. Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts. Transplantation. 2019 Feb; 103(2):363-370. PMID: 30422952.
    Citations:    Fields:    
  11. Navarro-Alvarez N, Machaidze Z, Schuetz C, Zhu A, Liu WH, Shah JA, Vagefi PA, Elias N, Buhler L, Sachs DH, Markmann JF, Yeh H. Xenogeneic Heterotopic Auxiliary Liver transplantation (XHALT) promotes native liver regeneration in a Post-Hepatectomy Liver failure model. PLoS One. 2018; 13(11):e0207272. PMID: 30462716.
    Citations:    Fields:    
  12. Eymard C, Markmann J. Normothermic ex vivo liver perfusion: platform for liver graft assessment and therapeutic modification. Organogenesis. 2018; 14(4):169-171. PMID: 30289350.
    Citations:    Fields:    
  13. Firl DJ, Kimura S, McVey J, Hashimoto K, Yeh H, Miller CM, Markmann JF, Sasaki K, Aucejo FN. Reframing the approach to patients with hepatocellular carcinoma: Longitudinal assessment with hazard associated with liver transplantation for HCC (HALTHCC) improves ablate and wait strategy. Hepatology. 2018 10; 68(4):1448-1458. PMID: 29604231.
    Citations: 1     Fields:    
  14. Michelakos T, Xourafas D, Qadan M, Pieretti-Vanmarcke R, Cai L, Patel MS, Adler JT, Fontan F, Basit U, Vagefi PA, Elias N, Tanabe KK, Berger D, Yeh H, Markmann JF, Chang DC, Ferrone CR. Hepatocellular Carcinoma in Transplantable Child-Pugh A Cirrhotics: Should Cost Affect Resection vs Transplantation? J Gastrointest Surg. 2019 Jun; 23(6):1135-1142. PMID: 30218342.
    Citations:    Fields:    
  15. Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S. Defining Outcomes for ß-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop. Transplantation. 2018 09; 102(9):1479-1486. PMID: 29528967.
    Citations: 1     Fields:    
  16. Martins PN, Brüggenwirth IMA, McDaid J, Hertl M, Kawai T, Elias N, Chung RT, Markmann JF. Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant. Exp Clin Transplant. 2018 Aug 17. PMID: 30119616.
    Citations:    Fields:    
  17. Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. Transplantation. 2018 08; 102(8):1223-1229. PMID: 29781950.
    Citations:    Fields:    
  18. Detelich D, Markmann JF. Normothermic liver preservation, current status and future directions. Curr Opin Organ Transplant. 2018 06; 23(3):347-352. PMID: 29629996.
    Citations:    Fields:    
  19. Beijert I, Mert S, Huang V, Karimian N, Geerts S, Hafiz EOA, Markmann JF, Yeh H, Porte RJ, Uygun K. Endothelial Dysfunction in Steatotic Human Donor Livers: A Pilot Study of the Underlying Mechanism During Subnormothermic Machine Perfusion. Transplant Direct. 2018 May; 4(5):e345. PMID: 29796416.
    Citations: 1     
  20. Markmann JF. Relaxing liver ischemia reperfusion injury down 1 notch. Am J Transplant. 2018 Jul; 18(7):1587-1588. PMID: 29569343.
    Citations:    Fields:    
  21. Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S. Defining outcomes for ß-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop. Transpl Int. 2018 04; 31(4):343-352. PMID: 29453879.
    Citations: 1     Fields:    Translation:Humans
  22. Detelich D, Markmann JF. The dawn of liver perfusion machines. Curr Opin Organ Transplant. 2018 04; 23(2):151-161. PMID: 29324518.
    Citations:    Fields:    
  23. Markmann JF. Commentary on Nurse Telephonic Triage Service for After-hour Patient Calls in Neurosurgery. Ann Surg. 2018 04; 267(4):e69. PMID: 29401108.
    Citations:    Fields:    
  24. Okulov IV, Okulov AV, Soldatov IV, Luthringer B, Willumeit-Römer R, Wada T, Kato H, Weissmüller J, Markmann J. Open porous dealloying-based biomaterials as a novel biomaterial platform. Mater Sci Eng C Mater Biol Appl. 2018 Jul 01; 88:95-103. PMID: 29636143.
    Citations:    Fields:    Translation:HumansCells
  25. Piemonti L, de Koning EJP, Berney T, Odorico JS, Markmann JF, Stock PG, Rickels MR. Defining outcomes for beta cell replacement therapy: a work in progress. Diabetologia. 2018 06; 61(6):1273-1276. PMID: 29511779.
    Citations: 2     Fields:    Translation:Humans
  26. Rezanejad H, Ouziel-Yahalom L, Keyzer CA, Sullivan BA, Hollister-Lock J, Li WC, Guo L, Deng S, Lei J, Markmann J, Bonner-Weir S. Heterogeneity of SOX9 and HNF1ß in Pancreatic Ducts Is Dynamic. Stem Cell Reports. 2018 03 13; 10(3):725-738. PMID: 29478894.
    Citations:    Fields:    
  27. Cao B, Adler JT, Bababekov YJ, Markmann JF, Chang DC, Yeh H. Pediatric kidney transplantation and mortality: Distance to transplant center matters. Pediatr Transplant. 2018 03; 22(2). PMID: 29316061.
    Citations: 1     Fields:    Translation:Humans
  28. Ben Nasr M, Tezza S, D'Addio F, Mameli C, Usuelli V, Maestroni A, Corradi D, Belletti S, Albarello L, Becchi G, Fadini GP, Schuetz C, Markmann J, Wasserfall C, Zon L, Zuccotti GV, Fiorina P. PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. Sci Transl Med. 2017 Nov 15; 9(416). PMID: 29141886.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  29. Avruch JH, Bruinsma BG, Weeder PD, Sridharan GV, Porte RJ, Yeh H, Markmann JF, Uygun K. A novel model for ex situ reperfusion of the human liver following subnormothermic machine perfusion. Technology (Singap World Sci). 2017 Dec; 5(4):196-200. PMID: 31106253.
    Citations:    
  30. Agopian VG, Harlander-Locke MP, Ruiz RM, Klintmalm GB, Senguttuvan S, Florman SS, Haydel B, Hoteit M, Levine MH, Lee DD, Taner CB, Verna EC, Halazun KJ, Abdelmessih R, Tevar AD, Humar A, Aucejo F, Chapman WC, Vachharajani N, Nguyen MH, Melcher ML, Nydam TL, Mobley C, Ghobrial RM, Amundsen B, Markmann JF, Langnas AN, Carney CA, Berumen J, Hemming AW, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Busuttil RW. Impact of Pretransplant Bridging Locoregional Therapy for Patients With Hepatocellular Carcinoma Within Milan Criteria Undergoing Liver Transplantation: Analysis of 3601 Patients From the US Multicenter HCC Transplant Consortium. Ann Surg. 2017 09; 266(3):525-535. PMID: 28654545.
    Citations: 12     Fields:    Translation:Humans
  31. Bruinsma BG, Avruch JH, Sridharan GV, Weeder PD, Jacobs ML, Crisalli K, Amundsen B, Porte RJ, Markmann JF, Uygun K, Yeh H. Peritransplant Energy Changes and Their Correlation to Outcome After Human Liver Transplantation. Transplantation. 2017 07; 101(7):1637-1644. PMID: 28230641.
    Citations: 1     Fields:    Translation:Humans
  32. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428. Diabetes. 2017 09; 66(9):2531. PMID: 28663189.
    Citations: 1     Fields:    
  33. Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden ES, Eidbo E, Lee WPA, Pomahac B, Brandacher G, Weinstock DM, Elliott G, Nelson D, Acker JP, Uygun K, Schmalz B, Weegman BP, Tocchio A, Fahy GM, Storey KB, Rubinsky B, Bischof J, Elliott JAW, Woodruff TK, Morris GJ, Demirci U, Brockbank KGM, Woods EJ, Ben RN, Baust JG, Gao D, Fuller B, Rabin Y, Kravitz DC, Taylor MJ, Toner M. The promise of organ and tissue preservation to transform medicine. Nat Biotechnol. 2017 06 07; 35(6):530-542. PMID: 28591112.
    Citations: 7     Fields:    Translation:Humans
  34. Shah JA, Patel MS, Elias N, Navarro-Alvarez N, Rosales I, Wilkinson RA, Louras NJ, Hertl M, Fishman JA, Colvin RB, Cosimi AB, Markmann JF, Sachs DH, Vagefi PA. Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade. Am J Transplant. 2017 Aug; 17(8):2178-2185. PMID: 28489305.
    Citations: 6     Fields:    Translation:Animals
  35. Ansite J, Balamurugan AN, Barbaro B, Battle J, Brandhorst D, Cano J, Chen X, Deng S, Feddersen D, Friberg A, Gilmore T, Goldstein JS, Holbrook E, Khan A, Kin T, Lei J, Linetsky E, Liu C, Luo X, McElvaney K, Min Z, Moreno J, O'Gorman D, Papas KK, Putz G, Ricordi C, Szot G, Templeton T, Wang L, Wilhelm JJ, Willits J, Wilson T, Zhang X, Avila J, Begley B, Cano J, Carpentier S, Holbrook E, Hutchinson J, Larsen CP, Moreno J, Sears M, Turgeon NA, Webster D, Deng S, Lei J, Markmann JF, Bridges ND, Czarniecki CW, Goldstein JS, Putz G, Templeton T, Wilson T, Eggerman TL, Al-Saden P, Battle J, Chen X, Hecyk A, Kissler H, Luo X, Molitch M, Monson N, Stuart E, Wallia A, Wang L, Wang S, Zhang X, Bigam D, Campbell P, Dinyari P, Kin T, Kneteman N, Lyon J, Malcolm A, O'Gorman D, Onderka C, Owen R, Pawlick R, Richer B, Rosichuk S, Sarman D, Schroeder A, Senior PA, Shapiro AMJ, Toth L, Toth V, Zhai W, Johnson K, McElroy J, Posselt AM, Ramos M, Rojas T, Stock PG, Szot G, Barbaro B, Martellotto J, Oberholzer J, Qi M, Wang Y, Bayman L, Chaloner K, Clarke W, Dillon JS, Diltz C, Doelle GC, Ecklund D, Feddersen D, Foster E, Hunsicker LG, Jasperson C, Lafontant DE, McElvaney K, Neill-Hudson T, Nollen D, Qidwai J, Riss H, Schwieger T, Willits J, Yankey J, Alejandro R, Corrales AC, Faradji R, Froud T, Garcia AA, Herrada E, Ichii H, Inverardi L, Kenyon N, Khan A, Linetsky E, Montelongo J, Peixoto E, Peterson K, Ricordi C, Szust J, Wang X, Abdulla MH, Ansite J, Balamurugan AN, Bellin MD, Brandenburg M, Gilmore T, Harmon JV, Hering BJ, Kandaswamy R, Loganathan G, Mueller K, Papas KK, Pedersen J, Wilhelm JJ, Witson J, Dalton-Bakes C, Fu H, Kamoun M, Kearns J, Li Y, Liu C, Luning-Prak E, Luo Y, Markmann E, Min Z, Naji A, Palanjian M, Rickels M, Shlansky-Goldberg R, Vivek K, Ziaie AS, Fernandez L, Kaufman DB, Zitur L, Brandhorst D, Friberg A, Korsgren O. Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide. CellR4 Repair Replace Regen Reprogram. 2017; 5(3). PMID: 30613755.
    Citations:    
  36. Goldberg DS, Karp SJ, McCauley ME, Markmann JF, Croome KP, Taner CB, Heimbach JK, Leise MD, Fryer JP, Bohorquez HE, Cohen AJ, Gilroy RK, Kumer SC, Foley DP, Karim AS, Hernandez-Alejandro R, Levstik MA, Abt PL. Interpreting Outcomes in DCDD Liver Transplantation: First Report of the Multicenter IDOL Consortium. Transplantation. 2017 05; 101(5):1067-1073. PMID: 28114173.
    Citations: 1     Fields:    Translation:Humans
  37. Schuetz C, Lee KM, Scott R, Kojima L, Washburn L, Liu L, Liu WH, Tector H, Lei J, Yeh H, Kim JI, Markmann JF. Regulatory B Cell-Dependent Islet Transplant Tolerance Is Also Natural Killer Cell Dependent. Am J Transplant. 2017 Jun; 17(6):1656-1662. PMID: 28296255.
    Citations: 2     Fields:    Translation:AnimalsCells
  38. Villani V, Gupta N, Elias N, Vagefi PA, Markmann JF, Paul E, Traum AZ, Yeh H. Bilateral native nephrectomy reduces systemic oxalate level after combined liver-kidney transplant: A case report. Pediatr Transplant. 2017 May; 21(3). PMID: 28261895.
    Citations: 1     Fields:    Translation:Humans
  39. Machaidze Z, Yeh H, Wei L, Schuetz C, Carvello M, Sgroi A, Smith RN, Schuurman HJ, Sachs DH, Morel P, Markmann JF, Bühler LH. Testing of microencapsulated porcine hepatocytes in a new model of fulminant liver failure in baboons. Xenotransplantation. 2017 05; 24(3). PMID: 28261903.
    Citations: 2     Fields:    Translation:AnimalsCells
  40. Okulov IV, Weissmüller J, Markmann J. Dealloying-based interpenetrating-phase nanocomposites matching the elastic behavior of human bone. Sci Rep. 2017 02 02; 7(1):20. PMID: 28154414.
    Citations: 1     Fields:    
  41. Markmann JF, Yeh H. The Beginnings of a Transplant Revolution. Ann Surg. 2017 01; 265(1):e3. PMID: 27464619.
    Citations:    Fields:    
  42. Shah JA, Patel MS, Kratz JR, Markmann JF, Vagefi PA.  High risk, high reward: An analysis of outcomes for candidates awaiting hepatic re-transplantation. Ann Hepatol. 2016 Nov-Dec 2016; 15(6):888-894. PMID: 27740522.
    Citations:    Fields:    Translation:Humans
  43. Adler JT, Bababekov YJ, Markmann JF, Chang DC, Yeh H. Distance is associated with mortality on the waitlist in pediatric liver transplantation. Pediatr Transplant. 2017 Mar; 21(2). PMID: 27804189.
    Citations:    Fields:    Translation:Humans
  44. Patel MS, Mohebali J, Shah JA, Markmann JF, Vagefi PA. Readmission following liver transplantation: an unwanted occurrence but an opportunity to act. HPB (Oxford). 2016 11; 18(11):936-942. PMID: 27642080.
    Citations: 1     Fields:    Translation:Humans
  45. Oura T, Hotta K, Lei J, Markmann J, Rosales I, Dehnadi A, Kawai K, Ndishabandi D, Smith RN, Cosimi AB, Kawai T. Immunosuppression With CD40 Costimulatory Blockade Plus Rapamycin for Simultaneous Islet-Kidney Transplantation in Nonhuman Primates. Am J Transplant. 2017 03; 17(3):646-656. PMID: 27501203.
    Citations: 4     Fields:    Translation:Animals
  46. Markmann JF. Signatures of Tolerance or Immunosuppression? Am J Transplant. 2016 12; 16(12):3320-3321. PMID: 27467554.
    Citations:    Fields:    
  47. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM, Chen X. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes. 2016 11; 65(11):3418-3428. PMID: 27465220.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  48. Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, Abdi R, Uehara M, Kim JI, Markmann JF, Tocco G, Benichou G. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Sci Immunol. 2016 Jul 14; 1(1). PMID: 27942611.
    Citations: 3     Fields:    
  49. Adler JT, Markmann JF, Yeh H. Renal allograft thrombosis after living donor transplantation: risk factors and obstacles to retransplantation. Clin Transplant. 2016 08; 30(8):864-71. PMID: 27101358.
    Citations: 2     Fields:    Translation:Humans
  50. Markmann JF, Bartlett ST, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, O'Connell PJ, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Khovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of ß-Cell Replacement. Transplantation. 2016 Jul; 100(7):e25-31. PMID: 27082827.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  51. Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, Abdi R, Uehara M, Kim JI, Markmann JF, Tocco G, Benichou G. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Sci Immunol. 2016 Jul 14; 1(1):aaf8759. PMID: 28783676.
    Citations: 11     Fields:    
  52. Karangwa SA, Dutkowski P, Fontes P, Friend PJ, Guarrera JV, Markmann JF, Mergental H, Minor T, Quintini C, Selzner M, Uygun K, Watson CJ, Porte RJ. Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines. Am J Transplant. 2016 10; 16(10):2932-2942. PMID: 27129409.
    Citations: 5     Fields:    Translation:Humans
  53. Madariaga ML, Spencer PJ, Shanmugarajah K, Crisalli KA, Chang DC, Markmann JF, Elias N, Cosimi AB, Sachs DH, Kawai T. Effect of tolerance versus chronic immunosuppression protocols on the quality of life of kidney transplant recipients. JCI Insight. 2016 Jun 02; 1(8). PMID: 27336062.
    Citations: 5     Fields:    
  54. Adler JT, Yeh H, Markmann JF, Axelrod DA. Is Donor Service Area Market Competition Associated With Organ Procurement Organization Performance? Transplantation. 2016 06; 100(6):1349-55. PMID: 26516674.
    Citations:    Fields:    Translation:Humans
  55. Shah JA, Navarro-Alvarez N, DeFazio M, Rosales IA, Elias N, Yeh H, Colvin RB, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. A Bridge to Somewhere: 25-day Survival After Pig-to-Baboon Liver Xenotransplantation. Ann Surg. 2016 06; 263(6):1069-71. PMID: 26825261.
    Citations: 9     Fields:    Translation:Animals
  56. Schuetz C, Markmann JF. Islet cell transplant: Update on current clinical trials. Curr Transplant Rep. 2016 Sep; 3(3):254-263. PMID: 28451515.
    Citations: 2     
  57. Hering BJ, Clarke WR, Bridges ND, Eggerman TL, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Markmann JF, Naji A, Oberholzer J, Posselt AM, Rickels MR, Ricordi C, Robien MA, Senior PA, Shapiro AM, Stock PG, Turgeon NA. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia. Diabetes Care. 2016 Jul; 39(7):1230-40. PMID: 27208344.
    Citations: 50     Fields:    Translation:HumansCTClinical Trials
  58. Xu Y, Navarro-Alvarez N, Yang C, Markmann JF, Dong J, Yeh H. A reliable scoring system after major liver resection in mice. J Surg Res. 2016 07; 204(1):75-82. PMID: 27451871.
    Citations:    Fields:    Translation:Animals
  59. Adler JT, Hyder JA, Markmann JF, Axelrod DA, Yeh H. Socioeconomic gradients between locally transplanted and exported liver donors and recipients. Liver Transpl. 2016 Apr; 22(4):557-8. PMID: 26845498.
    Citations:    Fields:    Translation:Humans
  60. Guinan EC, Cole GA, Wylie WH, Kelner RH, Janec KJ, Yuan H, Oppatt J, Brennan LL, Turka LA, Markmann J. Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation. Am J Transplant. 2016 07; 16(7):2187-95. PMID: 26790369.
    Citations: 4     Fields:    Translation:HumansCells
  61. Bruinsma BG, Sridharan GV, Weeder PD, Avruch JH, Saeidi N, Özer S, Geerts S, Porte RJ, Heger M, van Gulik TM, Martins PN, Markmann JF, Yeh H, Uygun K. Metabolic profiling during ex vivo machine perfusion of the human liver. Sci Rep. 2016 Mar 03; 6:22415. PMID: 26935866.
    Citations: 11     Fields:    Translation:Humans
  62. Adler JT, Yeh H, Markmann JF, Nguyen LL. Temporal Analysis of Market Competition and Density in Renal Transplantation Volume and Outcome. Transplantation. 2016 Mar; 100(3):670-7. PMID: 26574684.
    Citations:    Fields:    Translation:Humans
  63. Wang LJ, Kin T, O'Gorman D, Shapiro AMJ, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, Chen T, Lian M, Markmann JF, Alvarez A, Linetsky E, Ricordi C, Balamurugan AN, Loganathan G, Wilhelm JJ, Hering BJ, Bottino R, Trucco M, Liu C, Min Z, Li Y, Naji A, Fernandez LA, Ziemelis M, Danobeitia JS, Millis JM, Witkowski P. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation. Cell Transplant. 2016; 25(8):1515-1523. PMID: 26922947.
    Citations: 1     Fields:    Translation:Humans
  64. Sanchez-Fueyo A, Markmann JF. Immune Exhaustion and Transplantation. Am J Transplant. 2016 07; 16(7):1953-7. PMID: 26729653.
    Citations: 5     Fields:    Translation:Humans
  65. Navarro-Alvarez N, Shah JA, Zhu A, Ligocka J, Yeh H, Elias N, Rosales I, Colvin R, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. The Effects of Exogenous Administration of Human Coagulation Factors Following Pig-to-Baboon Liver Xenotransplantation. Am J Transplant. 2016 06; 16(6):1715-1725. PMID: 26613235.
    Citations: 7     Fields:    Translation:HumansAnimals
  66. Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, O'Connell P, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Kovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Report from IPITA-TTS Opinion Leaders Meeting on the Future of ß-Cell Replacement. Transplantation. 2016 Feb; 100 Suppl 2:S1-44. PMID: 26840096.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  67. Heher E, Markmann JF. The Clearer BENEFITS of Belatacept. N Engl J Med. 2016 Jan 28; 374(4):388-9. PMID: 26816017.
    Citations: 3     Fields:    Translation:Humans
  68. Fong ZV, Patel MS, Yeh H, Markmann JF, Vagefi PA. Liver transplantation utilizing a severely fractured graft: every organ counts. Ann Hepatol. 2016 Jan-Feb; 15(1):131-4. PMID: 26626650.
    Citations:    Fields:    Translation:Humans
  69. Markmann JF. Isolated Pancreatic Islet Transplantation: A Coming of Age. Am J Transplant. 2016 Feb; 16(2):381-2. PMID: 26595885.
    Citations:    Fields:    Translation:Humans
  70. Jain NG, Wong EA, Aranyosi AJ, Boneschansker L, Markmann JF, Briscoe DM, Irimia D. Microfluidic mazes to characterize T-cell exploration patterns following activation in vitro. Integr Biol (Camb). 2015 Nov; 7(11):1423-31. PMID: 26325525.
    Citations: 5     Fields:    Translation:HumansCells
  71. Jones CN, Dimisko L, Forrest K, Judice K, Poznansky MC, Markmann JF, Vyas JM, Irimia D. Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus. J Infect Dis. 2016 Feb 01; 213(3):465-75. PMID: 26272935.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  72. Wang P, Schuetz C, Vallabhajosyula P, Medarova Z, Tena A, Wei L, Yamada K, Deng S, Markmann JF, Sachs DH, Moore A. Monitoring of Allogeneic Islet Grafts in Nonhuman Primates Using MRI. Transplantation. 2015 Aug; 99(8):1574-81. PMID: 25806407.
    Citations: 2     Fields:    Translation:Animals
  73. Kim JI, Rothstein DM, Markmann JF. Role of B cells in tolerance induction. Curr Opin Organ Transplant. 2015 Aug; 20(4):369-75. PMID: 26107970.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  74. Ekser B, Markmann JF, Tector AJ. Current status of pig liver xenotransplantation. Int J Surg. 2015 Nov; 23(Pt B):240-246. PMID: 26190837.
    Citations: 3     Fields:    Translation:HumansAnimals
  75. Karimian N, Matton AP, Westerkamp AC, Burlage LC, Op den Dries S, Leuvenink HG, Lisman T, Uygun K, Markmann JF, Porte RJ. Ex Situ Normothermic Machine Perfusion of Donor Livers. J Vis Exp. 2015 May 26; (99):e52688. PMID: 26067131.
    Citations: 2     Fields:    Translation:Humans
  76. Lei J, Kim JI, Shi S, Zhang X, Machaidze Z, Lee S, Schuetz C, Martins PN, Oura T, Farkash EA, Rosales IA, Smith RN, Stott R, Lee KM, Soohoo J, Boskovic S, Cappetta K, Nadazdin OM, Yamada Y, Yeh H, Kawai T, Sachs DH, Benichou G, Markmann JF. Pilot Study Evaluating Regulatory T Cell-Promoting Immunosuppression and Nonimmunogenic Donor Antigen Delivery in a Nonhuman Primate Islet Allotransplantation Model. Am J Transplant. 2015 Oct; 15(10):2739-49. PMID: 26014796.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Adler JT, Yeh H, Markmann JF, Nguyen LL. Market Competition and Density in Liver Transplantation: Relationship to Volume and Outcomes. J Am Coll Surg. 2015 Aug; 221(2):524-31. PMID: 26206649.
    Citations:    Fields:    Translation:Humans
  78. Adler JT, Dong N, Markmann JF, Schoenfeld D, Yeh H. Role of Patient Factors and Practice Patterns in Determining Access to Liver Waitlist. Am J Transplant. 2015 Jul; 15(7):1836-42. PMID: 25931200.
    Citations: 3     Fields:    Translation:Humans
  79. Bruinsma BG, Avruch JH, Weeder PD, Sridharan GV, Uygun BE, Karimian NG, Porte RJ, Markmann JF, Yeh H, Uygun K. Functional human liver preservation and recovery by means of subnormothermic machine perfusion. J Vis Exp. 2015 Apr 27; (98). PMID: 25938299.
    Citations: 7     Fields:    Translation:Humans
  80. Bruinsma BG, Wu W, Ozer S, Farmer A, Markmann JF, Yeh H, Uygun K. Warm ischemic injury is reflected in the release of injury markers during cold preservation of the human liver. PLoS One. 2015; 10(3):e0123421. PMID: 25822248.
    Citations: 4     Fields:    Translation:Humans
  81. Ben Nasr M, Vergani A, Avruch J, Liu L, Kefaloyianni E, D'Addio F, Tezza S, Corradi D, Bassi R, Valderrama-Vasquez A, Usuelli V, Kim J, Azzi J, El Essawy B, Markmann J, Abdi R, Fiorina P. Co-transplantation of autologous MSCs delays islet allograft rejection and generates a local immunoprivileged site. Acta Diabetol. 2015 Oct; 52(5):917-27. PMID: 25808641.
    Citations: 14     Fields:    Translation:AnimalsCells
  82. Schuetz C, Markmann JF. Immunogenicity of ß-cells for autologous transplantation in type 1 diabetes. Pharmacol Res. 2015 Aug; 98:60-8. PMID: 25801943.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  83. Adler JT, Hyder JA, Elias N, Nguyen LL, Markmann JF, Delmonico FL, Yeh H. Socioeconomic status and ethnicity of deceased donor kidney recipients compared to their donors. Am J Transplant. 2015 Apr; 15(4):1061-7. PMID: 25758952.
    Citations:    Fields:    Translation:Humans
  84. Mehtsun WT, Patel MS, Markmann JF, Hertl M, Vagefi PA. Obstructive jaundice caused by a giant non-parasitic hepatic cyst. Ann Hepatol. 2015 Mar-Apr; 14(2):267-9. PMID: 25671837.
    Citations:    Fields:    Translation:Humans
  85. Chen T, Yuan J, Duncanson S, Hibert ML, Kodish BC, Mylavaganam G, Maker M, Li H, Sremac M, Santosuosso M, Forbes B, Kashiwagi S, Cao J, Lei J, Thomas M, Hartono C, Sachs D, Markmann J, Sambanis A, Poznansky MC. Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression. Am J Transplant. 2015 Mar; 15(3):618-27. PMID: 25693473.
    Citations: 8     Fields:    Translation:Animals
  86. Patel MS, Kohn R, Kratz JR, Shah JA, Markmann JF, Vagefi PA. The race to liver transplantation: a comparison of patients with and without hepatocellular carcinoma from listing to post-transplantation. J Am Coll Surg. 2015 Jun; 220(6):1001-7. PMID: 25868408.
    Citations: 6     Fields:    Translation:Humans
  87. Patel MS, Wright AJ, Kohn R, Markmann JF, Kotton CN, Vagefi PA. Successful long-term management of invasive cerebral fungal infection following liver transplantation. Mycoses. 2015 Mar; 58(3):181-6. PMID: 25590987.
    Citations: 2     Fields:    Translation:HumansAnimals
  88. Corritore E, Dugnani E, Pasquale V, Misawa R, Witkowski P, Lei J, Markmann J, Piemonti L, Sokal EM, Bonner-Weir S, Lysy PA. ß-Cell differentiation of human pancreatic duct-derived cells after in vitro expansion. Cell Reprogram. 2014 Dec; 16(6):456-66. PMID: 25437872.
    Citations: 8     Fields:    Translation:HumansCells
  89. Vagefi PA, Markmann JF. Liver transplantation: it's all about location, location, location: in reply to Lee and colleagues. J Am Coll Surg. 2014 Nov; 219(5):1100-1. PMID: 25440036.
    Citations:    Fields:    Translation:Humans
  90. Balamurugan AN, Naziruddin B, Lockridge A, Tiwari M, Loganathan G, Takita M, Matsumoto S, Papas K, Trieger M, Rainis H, Kin T, Kay TW, Wease S, Messinger S, Ricordi C, Alejandro R, Markmann J, Kerr-Conti J, Rickels MR, Liu C, Zhang X, Witkowski P, Posselt A, Maffi P, Secchi A, Berney T, O'Connell PJ, Hering BJ, Barton FB. Islet product characteristics and factors related to successful human islet transplantation from the Collaborative Islet Transplant Registry (CITR) 1999-2010. Am J Transplant. 2014 Nov; 14(11):2595-606. PMID: 25278159.
    Citations: 19     Fields:    Translation:Humans
  91. Adler JT, Sethi RK, Yeh H, Markmann JF, Nguyen LL. Market competition influences renal transplantation risk and outcomes. Ann Surg. 2014 Sep; 260(3):550-6; discussion 556-7. PMID: 25115431.
    Citations: 1     Fields:    Translation:Humans
  92. Patel MS, Kandula P, Wojciechowski D, Markmann JF, Vagefi PA. Trends in the management and outcomes of kidney transplantation for autosomal dominant polycystic kidney disease. J Transplant. 2014; 2014:675697. PMID: 25165573.
    Citations: 2     
  93. Yeh H, Machaidze Z, Wamala I, Fraser JW, Navarro-Alvarez N, Kim K, Schuetz C, Shi S, Zhu A, Hertl M, Elias N, Farkash EA, Vagefi PA, Varma M, Smith RN, Robson SC, Van Cott EM, Sachs DH, Markmann JF. Increased transfusion-free survival following auxiliary pig liver xenotransplantation. Xenotransplantation. 2014 Sep-Oct; 21(5):454-64. PMID: 25130043.
    Citations: 4     Fields:    Translation:Animals
  94. Kitchens WH, Yeh H, Markmann JF. Hepatic retransplant: what have we learned? Clin Liver Dis. 2014 Aug; 18(3):731-51. PMID: 25017086.
    Citations:    Fields:    Translation:Humans
  95. Zhao G, Moore DJ, Kim JI, Lee KM, O'Connor M, Yang M, Marshall AF, Lei J, Schuetz C, Markmann JF, Deng S. An immunosufficient murine model for the study of human islets. Xenotransplantation. 2014 Nov-Dec; 21(6):567-73. PMID: 25041432.
    Citations: 1     Fields:    Translation:HumansAnimals
  96. Lee KM, Stott RT, Zhao G, SooHoo J, Xiong W, Lian MM, Fitzgerald L, Shi S, Akrawi E, Lei J, Deng S, Yeh H, Markmann JF, Kim JI. TGF-ß-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance. Eur J Immunol. 2014 Jun; 44(6):1728-36. PMID: 24700192.
    Citations: 40     Fields:    Translation:AnimalsCells