Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

David Andrew Wellman, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL128658 (WELLMAN, DAVID ANDREW) Aug 10, 2016 - May 31, 2021
    Clinical Methods for Determining the Site and Severity of Pharyngeal Collapse
    Role: Principal Investigator
  2. R01HL102321 (WELLMAN, DAVID ANDREW) Apr 1, 2011 - Nov 30, 2021
    Validation of a Phenotype Model to Predict Response to Alternative OSA Treatments
    Role: Principal Investigator
  3. P01HL095491 (SAPER, CLIFFORD B) Apr 1, 2009 - May 31, 2021
    Mechanisms of Arousal in Sleep Apnea
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tan SN, Kim JM, Kim J, Sung CM, Kim HC, Lee J, Lim SC, White DP, Yang HC, Wellman DA. Head rotation improves airway obstruction, especially in patients with less severe obstructive sleep apnea without oropharyngeal collapse. PLoS One. 2022; 17(5):e0268455. PMID: 35609040; PMCID: PMC9129012.
    Citations:    Fields:    Translation:Humans
  2. Bamagoos AA, Cistulli PA, Sutherland K, Madronio M, Eckert DJ, Hess L, Edwards BA, Wellman A, Sands SA. Polysomnographic Endotyping to Select Patients with Obstructive Sleep Apnea for Oral Appliances. Ann Am Thorac Soc. 2019 11; 16(11):1422-1431. PMID: 31394914; PMCID: PMC6945467.
    Citations: 16     Fields:    Translation:Humans
  3. Azarbarzin A, Sands SA, Taranto-Montemurro L, Redline S, Wellman A. Hypoxic burden captures sleep apnoea-specific nocturnal hypoxaemia. Eur Heart J. 2019 09 14; 40(35):2989-2990. PMID: 31071210.
    Citations: 5     Fields:    Translation:Humans
  4. Azarbarzin A, Sands SA, White DP, Redline S, Wellman A. The hypoxic burden: a novel sleep apnoea severity metric and a predictor of cardiovascular mortality-Reply to 'The hypoxic burden: also known as the desaturation severity parameter'. Eur Heart J. 2019 09 14; 40(35):2994-2995. PMID: 31065680.
    Citations: 4     Fields:    Translation:Humans
  5. Mann DL, Terrill PI, Azarbarzin A, Mariani S, Franciosini A, Camassa A, Georgeson T, Marques M, Taranto-Montemurro L, Messineo L, Redline S, Wellman A, Sands SA. Quantifying the magnitude of pharyngeal obstruction during sleep using airflow shape. Eur Respir J. 2019 07; 54(1). PMID: 31000679; PMCID: PMC8679134.
    Citations: 14     Fields:    Translation:Humans
  6. Messineo L, Taranto-Montemurro L, Azarbarzin A, Marques M, Calianese N, White DP, Wellman A, Sands SA. Loop gain in REM versus non-REM sleep using CPAP manipulation: A pilot study. Respirology. 2019 08; 24(8):805-808. PMID: 31212392.
    Citations: 5     Fields:    
  7. Taranto-Montemurro L, Sands SA, Azarbarzin A, Wellman A. Reply to Patel and Althouse: Robust Methods Are Needed to Evaluate the Pharmacologic Treatment of Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2019 05 15; 199(10):1295-1296. PMID: 30807201; PMCID: PMC6519856.
    Citations:    Fields:    Translation:Humans
  8. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, Eckert DJ, White DP, Wellman A. The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial. Am J Respir Crit Care Med. 2019 05 15; 199(10):1267-1276. PMID: 30395486; PMCID: PMC6519859.
    Citations: 37     Fields:    Translation:Humans
  9. Azarbarzin A, Sands SA, Stone KL, Taranto-Montemurro L, Messineo L, Terrill PI, Ancoli-Israel S, Ensrud K, Purcell S, White DP, Redline S, Wellman A. The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study. Eur Heart J. 2019 04 07; 40(14):1149-1157. PMID: 30376054.
    Citations: 105     Fields:    Translation:Humans
  10. Wellman A. Airway distensibility: Bringing physiology to the bedside. Respirology. 2019 06; 24(6):607. PMID: 30945423.
    Citations:    Fields:    Translation:Humans
  11. Lim R, Carberry JC, Wellman A, Grunstein R, Eckert DJ. Reboxetine and hyoscine butylbromide improve upper airway function during nonrapid eye movement and suppress rapid eye movement sleep in healthy individuals. Sleep. 2019 04 01; 42(4). PMID: 30590857.
    Citations: 4     Fields:    Translation:Humans
  12. Amatoury J, Jordan AS, Toson B, Nguyen C, Wellman A, Eckert DJ. New insights into the timing and potential mechanisms of respiratory-induced cortical arousals in obstructive sleep apnea. Sleep. 2018 11 01; 41(11). PMID: 30137568.
    Citations: 5     Fields:    Translation:Humans
  13. Taranto-Montemurro L, Sands SA, Grace KP, Azarbarzin A, Messineo L, Salant R, White DP, Wellman DA. Neural memory of the genioglossus muscle during sleep is stage-dependent in healthy subjects and obstructive sleep apnoea patients. J Physiol. 2018 11; 596(21):5163-5173. PMID: 30022493; PMCID: PMC6209751.
    Citations: 4     Fields:    Translation:Humans
  14. Marques M, Genta PR, Azarbarzin A, Sands SA, Taranto-Montemurro L, Messineo L, White DP, Wellman A. Retropalatal and retroglossal airway compliance in patients with obstructive sleep apnea. Respir Physiol Neurobiol. 2018 12; 258:98-103. PMID: 29913264.
    Citations: 6     Fields:    Translation:Humans
  15. Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, Frazier-Wood AC, Gharib SA, Haba-Rubio J, Hagen EW, Heinzer R, Hillman DR, Johnson WC, Kutalik Z, Lane JM, Larkin EK, Lee SK, Liang J, Loredo JS, Mukherjee S, Palmer LJ, Papanicolaou GJ, Penzel T, Peppard PE, Post WS, Ramos AR, Rice K, Rotter JI, Sands SA, Shah NA, Shin C, Stone KL, Stubbe B, Sul JH, Tafti M, Taylor KD, Teumer A, Thornton TA, Tranah GJ, Wang C, Wang H, Warby SC, Wellman DA, Zee PC, Hanis CL, Laurie CC, Gottlieb DJ, Patel SR, Zhu X, Sunyaev SR, Saxena R, Lin X, Redline S. Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 03; 58(3):391-401. PMID: 29077507; PMCID: PMC5854957.
    Citations: 25     Fields:    Translation:Humans
  16. Messineo L, Taranto-Montemurro L, Sands SA, Oliveira Marques MD, Azabarzin A, Wellman DA. Broadband Sound Administration Improves Sleep Onset Latency in Healthy Subjects in a Model of Transient Insomnia. Front Neurol. 2017; 8:718. PMID: 29312136; PMCID: PMC5742584.
    Citations: 5     
  17. Wellman A, Genta PR, Owens RL, Edwards BA, Sands SA, Loring SH, White DP, Jackson AC, Pedersen OF, Butler JP. Test of the Starling resistor model in the human upper airway during sleep. J Appl Physiol (1985). 2014 Dec 15; 117(12):1478-85. PMID: 25324514.
    Citations: 9     Fields:    Translation:Humans
  18. Wellman A, Edwards BA, Sands SA, Owens RL, Nemati S, Butler J, Passaglia CL, Jackson AC, Malhotra A, White DP. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. J Appl Physiol (1985). 2013 Apr; 114(7):911-22. PMID: 23349453.
    Citations: 86     Fields:    Translation:Humans
  19. Wellman A, Eckert DJ, Jordan AS, Edwards BA, Passaglia CL, Jackson AC, Gautam S, Owens RL, Malhotra A, White DP. A method for measuring and modeling the physiological traits causing obstructive sleep apnea. J Appl Physiol (1985). 2011 Jun; 110(6):1627-37. PMID: 21436459.
    Citations: 86     Fields:    Translation:Humans
  20. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: Role of loop gain. Respir Physiol Neurobiol. 2008.
  21. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: role of loop gain. Respir Physiol Neurobiol. 2008 Jul 31; 162(2):144-51. PMID: 18577470.
    Citations: 90     Fields:    Translation:Humans
  22. A Wellman, AS Jordan, D Eckert, S Smith, A Schomer, A Malhotra, DP White. A new technique for measuring ventilatory control stability (loop gain). American Thoracic Society, American Professional Sleep Societies. 2008.
  23. Jordan AS, Wellman A, Heinzer RC, Lo YL, Schory K, Dover L, Gautam S, Malhotra A, White DP. Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans. Thorax. 2007 Oct; 62(10):861-7. PMID: 17412778.
    Citations: 47     Fields:    Translation:Humans
  24. Eikermann M, Jordan AS, Chamberlin NL, Gautam S, Wellman A, Lo YL, White DP, Malhotra A. The influence of aging on pharyngeal collapsibility during sleep. Chest. 2007 Jun; 131(6):1702-9. PMID: 17413053; PMCID: PMC2278166.
    Citations: 78     Fields:    Translation:Humans
  25. Lo YL, Jordan AS, Malhotra A, Wellman A, Heinzer RA, Eikermann M, Schory K, Dover L, White DP. Influence of wakefulness on pharyngeal airway muscle activity. Thorax. 2007 Sep; 62(9):799-805. PMID: 17389755.
    Citations: 30     Fields:    Translation:Humans
  26. Wellman A, Malhotra A, Jordan AS, Schory K, Gautam S, White DP. Chemical control stability in the elderly. J Physiol. 2007 May 15; 581(Pt 1):291-8. PMID: 17317747; PMCID: PMC2075232.
    Citations: 23     Fields:    Translation:Humans
  27. Lo YL, Jordan AS, Malhotra A, Wellman A, Heinzer RC, Schory K, Dover L, Fogel RB, White DP. Genioglossal muscle response to CO2 stimulation during NREM sleep. Sleep. 2006 Apr; 29(4):470-7. PMID: 16676780.
    Citations: 31     Fields:    Translation:Humans
  28. Heinzer RC, Stanchina ML, Malhotra A, Jordan AS, Patel SR, Lo YL, Wellman A, Schory K, Dover L, White DP. Effect of increased lung volume on sleep disordered breathing in patients with sleep apnoea. Thorax. 2006 May; 61(5):435-9. PMID: 16490766.
    Citations: 60     Fields:    Translation:Humans
  29. Jordan AS, Wellman A, Edwards JK, Schory K, Dover L, MacDonald M, Patel SR, Fogel RB, Malhotra A, White DP. Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea. J Appl Physiol (1985). 2005 Nov; 99(5):2020-7. PMID: 15994243; PMCID: PMC3496786.
    Citations: 44     Fields:    Translation:Humans
  30. Wellman D.A., Malhotra A., Jordan A.S., Fogel R.B., Schory K., White D.P. Ventilatory Instability is not Increased in the Elderly. American Thoracic Society. 2005.
  31. A. Wellman, A.S. Jordan, A. Malhotra, R.B. Fogel, K. Schory, L. Dover and D.P. White. Oxygen reduces apnea in obstructive sleep apnea with increased ventilatory instability. Am J Resp and Crit Care Med. 2005; 2:A303.
  32. RC Heinzer, A Malhotra, AS Jordan, DA Wellman and DP White. Effect of CPAP and Lung Volume on Obstructive Sleep Apnea. Am J Resp Crit Care Med. 2005; 172:1350-1351.
  33. Wellman A, Jordan AS, Malhotra A, Fogel RB, Katz ES, Schory K, Edwards JK, White DP. Ventilatory control and airway anatomy in obstructive sleep apnea. Am J Respir Crit Care Med. 2004 Dec 01; 170(11):1225-32. PMID: 15317668; PMCID: PMC3861244.
    Citations: 102     Fields:    Translation:Humans
  34. A. Malhotra, R.B. Fogel, A. Wellman, S.R. Patel, K. Schory, D.P. White. Menopausal effects on upper airway muscle activity and mechanics. Am J Resp and Crit Care Med. 2004; 168(7):A434.
  35. Moss M, Wellman DA, Cotsonis GA. An appraisal of multivariable logistic models in the pulmonary and critical care literature. Chest. 2003 Mar; 123(3):923-8. PMID: 12628895.
    Citations: 22     Fields:    Translation:Humans
  36. A. Malhotra, R.B. Fogel, D.A. Wellman, M.L. Stanchina, A. Jordan, K. Schory, G. Pillar, D.P. White. State dependence of gender differences in upper airway reflexes. Am J Resp and Crit Care Med. 2003; 167(7):A303.
  37. Wellman A., A.S. Jordan, R.B. Fogel, K. Schory, J. Raneri, M. MacDonald, D.P. White. Defining the role of ventilatory control instability in obstructive sleep apnea. American Thoracic Society. 2003.
  38. A.S. Jordan, A. Wellman, R.B. Fogel, R.J. Pierce, A. Malhotra, J.K. Edwards, K. Schory, D.P. White. Pharyngeal critical closing pressure measurement without respiratory effort: A validation study. Am J Resp and Crit Care Med. 2003; 167(7):A600.
  39. AS Jordan, RD McEvoy, JK Edwards, K Schory, PG Catcheside, A Wellman, RB Fogel, A Malhotra, DP White. Ventilatory response to arousal in obstructive sleep apnea. American Professional Sleep Societies. 2003.
  40. Wellman A, Malhotra A, Fogel RB, Edwards JK, Schory K, White DP. Respiratory system loop gain in normal men and women measured with proportional-assist ventilation. J Appl Physiol (1985). 2003 Jan; 94(1):205-12. PMID: 12391042.
    Citations: 17     Fields:    Translation:Humans
  41. Wellman A, Malhotra A, White DP. Atrial pacing in sleep apnea syndrome. N Engl J Med. 2002 Aug 08; 347(6):445-6; author reply 445-6. PMID: 12167690.
    Citations: 1     Fields:    Translation:Humans
  42. Wellman DA, Malhotra A, Fogel RB, Edwards JK, Schory K, White DP . Gender influences on respiratory loop gain. American Thoracic Society. 2002.
  43. Kuhn WF, Wellman A. The use of melatonin as a potential treatment for shiftwork sleep disorder. Acad Emerg Med. 1998 Aug; 5(8):842-3. PMID: 9715249.
    Citations:    Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Wellman's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (115)
Co-Authors (19)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.