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David Andrew Wellman, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL128658 (WELLMAN, DAVID ANDREW) Aug 10, 2016 - May 31, 2020
    NIH/NHLBI
    Clinical Methods for Determining the Site and Severity of Pharyngeal Collapse
    Role: Principal Investigator
  2. R01HL102321 (WELLMAN, DAVID ANDREW) Apr 1, 2011 - Nov 30, 2020
    NIH/NHLBI
    Validation of a Phenotype Model to Predict Response to Alternative OSA Treatments
    Role: Principal Investigator
  3. P01HL095491 (SAPER, CLIFFORD B) Apr 1, 2009 - May 31, 2020
    NIH/NHLBI
    Mechanisms of Arousal in Sleep Apnea
    Role: Co-Principal Investigator
  4. F32HL072560 (WELLMAN, DAVID A) May 1, 2003 - Apr 30, 2005
    NIH/NHLBI
    Respiratory Control Stability in Obstructive Sleep Apnea
    Role: Principal Investigator
  5. M01RR001032 (SUKHATME, VIKAS P) Dec 1, 1977 - Mar 31, 2010
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Taranto-Montemurro L, Sands SA, Grace KP, Azarbarzin A, Messineo L, Salant R, White DP, Wellman DA. Neural memory of the genioglossus muscle during sleep is stage-dependent in healthy subjects and obstructive sleep apnoea patients. J Physiol. 2018 Nov; 596(21):5163-5173. PMID: 30022493.
    View in: PubMed
  2. Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, Frazier-Wood AC, Gharib SA, Haba-Rubio J, Hagen EW, Heinzer R, Hillman DR, Johnson WC, Kutalik Z, Lane JM, Larkin EK, Lee SK, Liang J, Loredo JS, Mukherjee S, Palmer LJ, Papanicolaou GJ, Penzel T, Peppard PE, Post WS, Ramos AR, Rice K, Rotter JI, Sands SA, Shah NA, Shin C, Stone KL, Stubbe B, Sul JH, Tafti M, Taylor KD, Teumer A, Thornton TA, Tranah GJ, Wang C, Wang H, Warby SC, Wellman DA, Zee PC, Hanis CL, Laurie CC, Gottlieb DJ, Patel SR, Zhu X, Sunyaev SR, Saxena R, Lin X, Redline S. Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 03; 58(3):391-401. PMID: 29077507.
    View in: PubMed
  3. Messineo L, Taranto-Montemurro L, Sands SA, Oliveira Marques MD, Azabarzin A, Wellman DA. Broadband Sound Administration Improves Sleep Onset Latency in Healthy Subjects in a Model of Transient Insomnia. Front Neurol. 2017; 8:718. PMID: 29312136.
    View in: PubMed
  4. Wellman A, Genta PR, Owens RL, Edwards BA, Sands SA, Loring SH, White DP, Jackson AC, Pedersen OF, Butler JP. Test of the Starling resistor model in the human upper airway during sleep. J Appl Physiol (1985). 2014 Dec 15; 117(12):1478-85. PMID: 25324514; PMCID: PMC4269684.
  5. Wellman A, Edwards BA, Sands SA, Owens RL, Nemati S, Butler J, Passaglia CL, Jackson AC, Malhotra A, White DP. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. J Appl Physiol (1985). 2013 Apr; 114(7):911-22. PMID: 23349453.
    View in: PubMed
  6. Wellman A, Eckert DJ, Jordan AS, Edwards BA, Passaglia CL, Jackson AC, Gautam S, Owens RL, Malhotra A, White DP. A method for measuring and modeling the physiological traits causing obstructive sleep apnea. J Appl Physiol (1985). 2011 Jun; 110(6):1627-37. PMID: 21436459; PMCID: PMC3119134.
  7. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: role of loop gain. Respir Physiol Neurobiol. 2008 Jul 31; 162(2):144-51. PMID: 18577470; PMCID: PMC4332598.
  8. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: Role of loop gain. Respir Physiol Neurobiol. 2008.
  9. A Wellman, AS Jordan, D Eckert, S Smith, A Schomer, A Malhotra, DP White. A new technique for measuring ventilatory control stability (loop gain). American Thoracic Society, American Professional Sleep Societies. 2008.
  10. Jordan AS, Wellman A, Heinzer RC, Lo YL, Schory K, Dover L, Gautam S, Malhotra A, White DP. Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans. Thorax. 2007 Oct; 62(10):861-7. PMID: 17412778; PMCID: PMC2094262.
  11. Eikermann M, Jordan AS, Chamberlin NL, Gautam S, Wellman A, Lo YL, White DP, Malhotra A. The influence of aging on pharyngeal collapsibility during sleep. Chest. 2007 Jun; 131(6):1702-9. PMID: 17413053; PMCID: PMC2278166.
  12. Lo YL, Jordan AS, Malhotra A, Wellman A, Heinzer RA, Eikermann M, Schory K, Dover L, White DP. Influence of wakefulness on pharyngeal airway muscle activity. Thorax. 2007 Sep; 62(9):799-805. PMID: 17389755; PMCID: PMC2117303.
  13. Wellman A, Malhotra A, Jordan AS, Schory K, Gautam S, White DP. Chemical control stability in the elderly. J Physiol. 2007 May 15; 581(Pt 1):291-8. PMID: 17317747; PMCID: PMC2075232.
  14. Lo YL, Jordan AS, Malhotra A, Wellman A, Heinzer RC, Schory K, Dover L, Fogel RB, White DP. Genioglossal muscle response to CO2 stimulation during NREM sleep. Sleep. 2006 Apr; 29(4):470-7. PMID: 16676780; PMCID: PMC3500386.
  15. Heinzer RC, Stanchina ML, Malhotra A, Jordan AS, Patel SR, Lo YL, Wellman A, Schory K, Dover L, White DP. Effect of increased lung volume on sleep disordered breathing in patients with sleep apnoea. Thorax. 2006 May; 61(5):435-9. PMID: 16490766; PMCID: PMC2111199.
  16. Jordan AS, Wellman A, Edwards JK, Schory K, Dover L, MacDonald M, Patel SR, Fogel RB, Malhotra A, White DP. Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea. J Appl Physiol (1985). 2005 Nov; 99(5):2020-7. PMID: 15994243; PMCID: PMC3496786.
  17. A. Wellman, A.S. Jordan, A. Malhotra, R.B. Fogel, K. Schory, L. Dover and D.P. White. Oxygen reduces apnea in obstructive sleep apnea with increased ventilatory instability. Am J Resp and Crit Care Med. 2005; 2:A303.
  18. RC Heinzer, A Malhotra, AS Jordan, DA Wellman and DP White. Effect of CPAP and Lung Volume on Obstructive Sleep Apnea. Am J Resp Crit Care Med. 2005; 172:1350-1351.
  19. Wellman D.A., Malhotra A., Jordan A.S., Fogel R.B., Schory K., White D.P. Ventilatory Instability is not Increased in the Elderly. American Thoracic Society. 2005.
  20. Wellman A, Jordan AS, Malhotra A, Fogel RB, Katz ES, Schory K, Edwards JK, White DP. Ventilatory control and airway anatomy in obstructive sleep apnea. Am J Respir Crit Care Med. 2004 Dec 01; 170(11):1225-32. PMID: 15317668; PMCID: PMC3861244.
  21. A. Malhotra, R.B. Fogel, A. Wellman, S.R. Patel, K. Schory, D.P. White. Menopausal effects on upper airway muscle activity and mechanics. Am J Resp and Crit Care Med. 2004; 168(7):A434.
  22. Moss M, Wellman DA, Cotsonis GA. An appraisal of multivariable logistic models in the pulmonary and critical care literature. Chest. 2003 Mar; 123(3):923-8. PMID: 12628895.
    View in: PubMed
  23. AS Jordan, RD McEvoy, JK Edwards, K Schory, PG Catcheside, A Wellman, RB Fogel, A Malhotra, DP White. Ventilatory response to arousal in obstructive sleep apnea. American Professional Sleep Societies. 2003.
  24. A.S. Jordan, A. Wellman, R.B. Fogel, R.J. Pierce, A. Malhotra, J.K. Edwards, K. Schory, D.P. White. Pharyngeal critical closing pressure measurement without respiratory effort: A validation study. Am J Resp and Crit Care Med. 2003; 167(7):A600.
  25. Wellman A., A.S. Jordan, R.B. Fogel, K. Schory, J. Raneri, M. MacDonald, D.P. White. Defining the role of ventilatory control instability in obstructive sleep apnea. American Thoracic Society. 2003.
  26. A. Malhotra, R.B. Fogel, D.A. Wellman, M.L. Stanchina, A. Jordan, K. Schory, G. Pillar, D.P. White. State dependence of gender differences in upper airway reflexes. Am J Resp and Crit Care Med. 2003; 167(7):A303.
  27. Wellman A, Malhotra A, Fogel RB, Edwards JK, Schory K, White DP. Respiratory system loop gain in normal men and women measured with proportional-assist ventilation. J Appl Physiol (1985). 2003 Jan; 94(1):205-12. PMID: 12391042.
    View in: PubMed
  28. Wellman A, Malhotra A, White DP. Atrial pacing in sleep apnea syndrome. N Engl J Med. 2002 Aug 08; 347(6):445-6; author reply 445-6. PMID: 12167690.
    View in: PubMed
  29. Wellman DA, Malhotra A, Fogel RB, Edwards JK, Schory K, White DP . Gender influences on respiratory loop gain. American Thoracic Society. 2002.
  30. Kuhn WF, Wellman A. The use of melatonin as a potential treatment for shiftwork sleep disorder. Acad Emerg Med. 1998 Aug; 5(8):842-3. PMID: 9715249.
    View in: PubMed
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.