Harvard Catalyst Profiles

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Christa Nehs, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Melonakos ED, Siegmann MJ, Rey C, O'Brien C, Nikolaeva KK, Solt K, Nehs CJ. Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia. Anesthesiology. 2021 10 01; 135(4):633-648. PMID: 34270686; PMCID: PMC8440361.
    Citations:    Fields:    Translation:AnimalsCells
  2. Kato R, Zhang ER, Mallari OG, Moody OA, Vincent KF, Melonakos ED, Siegmann MJ, Nehs CJ, Houle TT, Akeju O, Solt K. D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats. Front Pharmacol. 2021; 12:668285. PMID: 34084141.
    Citations: 2     
  3. Moody OA, Zhang ER, Vincent KF, Kato R, Melonakos ED, Nehs CJ, Solt K. The Neural Circuits Underlying General Anesthesia and Sleep. Anesth Analg. 2021 05 01; 132(5):1254-1264. PMID: 33857967; PMCID: PMC8054915.
    Citations: 3     Fields:    Translation:HumansAnimals
  4. Vlasov K, Pei J, Nehs CJ, Guidera JA, Zhang ER, Kenny JD, Houle TT, Brenner GJ, Taylor NE, Solt K. Activation of GABAergic Neurons in the Rostromedial Tegmental Nucleus and Other Brainstem Regions Promotes Sedation and Facilitates Sevoflurane Anesthesia in Mice. Anesth Analg. 2021 04 01; 132(4):e50-e55. PMID: 33560660; PMCID: PMC7969415.
    Citations: 1     Fields:    Translation:AnimalsCells
  5. Melonakos ED, Moody OA, Nikolaeva K, Kato R, Nehs CJ, Solt K. Manipulating Neural Circuits in Anesthesia Research. Anesthesiology. 2020 07; 133(1):19-30. PMID: 32349073; PMCID: PMC8351362.
    Citations: 5     Fields:    Translation:HumansAnimals
  6. Taylor NE, Pei J, Zhang J, Vlasov KY, Davis T, Taylor E, Weng FJ, Van Dort CJ, Solt K, Brown EN. The Role of Glutamatergic and Dopaminergic Neurons in the Periaqueductal Gray/Dorsal Raphe: Separating Analgesia and Anxiety. eNeuro. 2019 Jan-Feb; 6(1). PMID: 31058210; PMCID: PMC6498422.
    Citations: 23     Fields:    Translation:AnimalsCells
  7. Siegmann MJ, Athinarayanan SJ, Hallberg SJ, McKenzie AL, Bhanpuri NH, Campbell WW, McCarter JP, Phinney SD, Volek JS, Van Dort CJ. Improvement in patient-reported sleep in type 2 diabetes and prediabetes participants receiving a continuous care intervention with nutritional ketosis. Sleep Med. 2019 03; 55:92-99. PMID: 30772699.
    Citations: 6     Fields:    Translation:Humans
  8. Vlasov K, Van Dort CJ, Solt K. Optogenetics and Chemogenetics. Methods Enzymol. 2018; 603:181-196. PMID: 29673525; PMCID: PMC6984397.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  9. Zhang H, Zhao H, Zeng C, Van Dort C, Faingold CL, Taylor NE, Solt K, Feng HJ. Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model. Neurobiol Dis. 2018 02; 110:47-58. PMID: 29141182; PMCID: PMC5748009.
    Citations: 32     Fields:    Translation:AnimalsCells
  10. Kenny JD, Chemali JJ, Cotten JF, Van Dort CJ, Kim SE, Ba D, Taylor NE, Brown EN, Solt K. Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats. Anesth Analg. 2016 11; 123(5):1210-1219. PMID: 26991753; PMCID: PMC5026857.
    Citations: 17     Fields:    Translation:Animals
  11. Taylor NE, Van Dort CJ, Kenny JD, Pei J, Guidera JA, Vlasov KY, Lee JT, Boyden ES, Brown EN, Solt K. Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia. Proc Natl Acad Sci U S A. 2016 Nov 08; 113(45):12826-12831. PMID: 27791160; PMCID: PMC5111696.
    Citations: 85     Fields:    
  12. Muindi F, Kenny JD, Taylor NE, Solt K, Wilson MA, Brown EN, Van Dort CJ. Electrical stimulation of the parabrachial nucleus induces reanimation from isoflurane general anesthesia. Behav Brain Res. 2016 06 01; 306:20-5. PMID: 26971629.
    Citations: 23     Fields:    Translation:Animals
  13. Van Dort CJ. Locus Coeruleus Neural Fatigue: A Potential Mechanism for Cognitive Impairment during Sleep Deprivation. Sleep. 2016 Jan 01; 39(1):11-2. PMID: 26564138.
    Citations: 2     Fields:    Translation:Humans
  14. Van Dort CJ, Brown EN. Reply to Grace: Role of cholinergic neurons in rapid eye movement (REM) sleep control. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):E3756. PMID: 26124152; PMCID: PMC4517216.
    Citations: 1     Fields:    Translation:AnimalsCells
  15. Van Dort CJ, Zachs DP, Kenny JD, Zheng S, Goldblum RR, Gelwan NA, Ramos DM, Nolan MA, Wang K, Weng FJ, Lin Y, Wilson MA, Brown EN. Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):584-9. PMID: 25548191; PMCID: PMC4299243.
    Citations: 92     Fields:    Translation:AnimalsCells
  16. Solt K, Van Dort CJ, Chemali JJ, Taylor NE, Kenny JD, Brown EN. Electrical stimulation of the ventral tegmental area induces reanimation from general anesthesia. Anesthesiology. 2014 Aug; 121(2):311-9. PMID: 24398816; PMCID: PMC4112744.
    Citations: 65     Fields:    Translation:Animals
  17. Solt K, Chemali JJ, Van Dort CJ, Brown EN. In reply. Anesthesiology. 2012 Dec; 117(6):1394-5. PMID: 23168434.
  18. Chemali JJ, Van Dort CJ, Brown EN, Solt K. Active emergence from propofol general anesthesia is induced by methylphenidate. Anesthesiology. 2012 May; 116(5):998-1005. PMID: 22446983; PMCID: PMC3339625.
    Citations: 53     Fields:    Translation:Animals
  19. Brown EN, Purdon PL, Van Dort CJ. General anesthesia and altered states of arousal: a systems neuroscience analysis. Annu Rev Neurosci. 2011; 34:601-28. PMID: 21513454.
    Citations: 175     Fields:    Translation:HumansAnimals
  20. Van Dort CJ, Baghdoyan HA, Lydic R. Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal. J Neurosci. 2009 Jan 21; 29(3):871-81. PMID: 19158311.
    Citations: 66     Fields:    Translation:Animals
  21. Van Dort CJ, Baghdoyan HA, Lydic R. Neurochemical modulators of sleep and anesthetic states. Int Anesthesiol Clin. 2008; 46(3):75-104. PMID: 18617819.
    Citations: 10     Fields:    Translation:HumansAnimals
  22. Buchwalter A, Van Dort C, Schultz S, Smith R, Le IP, Abbott JL, Oosterhouse E, Johnson AE, Hansen-Smith F, Burnatowska-Hledin M. Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype. Microvasc Res. 2008 Mar; 75(2):155-68. PMID: 17950367.
    Citations: 8     Fields:    Translation:AnimalsCells
  23. Burnatowska-Hledin MA, Kossoris JB, Van Dort CJ, Shearer RL, Zhao P, Murrey DA, Abbott JL, Kan CE, Barney CC. T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene. Biochem Biophys Res Commun. 2004 Jul 02; 319(3):817-25. PMID: 15184056.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  24. Van Dort C, Zhao P, Parmelee K, Capps B, Poel A, Listenberger L, Kossoris J, Wasilevich B, Murrey D, Clare P, Burnatowska-Hledin M. VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathways. Am J Physiol Cell Physiol. 2003 Dec; 285(6):C1386-96. PMID: 12917106.
    Citations: 11     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.