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profileKeertik Fulzele, Ph.D.

TitleInstructor in Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Thier 11
50 Blossom St
Boston MA 02114
Phone617/726-3966
Fax617/726-7543
vCardDownload vCard (login for email)

Collapse Biography 
Collapse awards and honors
2010The Most Outstanding Abstract Award
2010Alice L. Jee Memorial Young Investigator Award
2010First Prize, Annual Research Fellows Poster Celebration
2011Young Investigator Award
2013John Haddad Young Investigator Award

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fulzele K, Lai F, Dedic C, Saini V, Uda Y, Shi C, Tuck P, Aronson JL, Liu X, Spatz JM, Wein MN, Divieti Pajevic P. Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots. J Bone Miner Res. 2017 Feb; 32(2):373-384. PMID: 27653320.
    View in: PubMed
  2. Panaroni C, Fulzele K, Saini V, Chubb R, Pajevic PD, Wu JY. PTH Signaling in Osteoprogenitors Is Essential for B-Lymphocyte Differentiation and Mobilization. J Bone Miner Res. 2015 Dec; 30(12):2273-86. PMID: 26191777.
    View in: PubMed
  3. Sinha P, Aarnisalo P, Chubb R, Ono N, Fulzele K, Selig M, Saeed H, Chen M, Weinstein LS, Pajevic PD, Kronenberg HM, Wu JY. Loss of Gsa early in the osteoblast lineage favors adipogenic differentiation of mesenchymal progenitors and committed osteoblast precursors. J Bone Miner Res. 2014 Nov; 29(11):2414-26. PMID: 24806274; PMCID: PMC4220542.
  4. Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT. Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nat Med. 2013 Nov; 19(11):1513-7. PMID: 24162813; PMCID: PMC3827980.
  5. Saini V, Marengi DA, Barry KJ, Fulzele KS, Heiden E, Liu X, Dedic C, Maeda A, Lotinun S, Baron R, Pajevic PD. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12; 288(28):20122-34. PMID: 23729679; PMCID: PMC3711281.
  6. Fulzele K, Krause DS, Panaroni C, Saini V, Barry KJ, Liu X, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Wu JY, Kronenberg HM, Scadden DT, Divieti Pajevic P. Myelopoiesis is regulated by osteocytes through Gsa-dependent signaling. Blood. 2013 Feb 07; 121(6):930-9. PMID: 23160461; PMCID: PMC3567340.
  7. Wu JY, Aarnisalo P, Bastepe M, Sinha P, Fulzele K, Selig MK, Chen M, Poulton IJ, Purton LE, Sims NA, Weinstein LS, Kronenberg HM. Gsa enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice. J Clin Invest. 2011 Sep; 121(9):3492-504. PMID: 21804192; PMCID: PMC3163961.
  8. Fulzele K, Clemens TL. Novel functions for insulin in bone. Bone. 2012 Feb; 50(2):452-6. PMID: 21723973.
    View in: PubMed
  9. Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL. Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell. 2010 Jul 23; 142(2):309-19. PMID: 20655471; PMCID: PMC2925155.
  10. DeMambro VE, Kawai M, Clemens TL, Fulzele K, Maynard JA, Marín de Evsikova C, Johnson KR, Canalis E, Beamer WG, Rosen CJ, Donahue LR. A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis. J Endocrinol. 2010 Mar; 204(3):241-53. PMID: 20032200; PMCID: PMC3033737.
  11. DiGirolamo DJ, Mukherjee A, Fulzele K, Gan Y, Cao X, Frank SJ, Clemens TL. Mode of growth hormone action in osteoblasts. J Biol Chem. 2007 Oct 26; 282(43):31666-74. PMID: 17698843.
    View in: PubMed
  12. Fulzele K, DiGirolamo DJ, Liu Z, Xu J, Messina JL, Clemens TL. Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action. J Biol Chem. 2007 Aug 31; 282(35):25649-58. PMID: 17553792.
    View in: PubMed
  13. Elder SH, Fulzele KS, McCulley WR. Cyclic hydrostatic compression stimulates chondroinduction of C3H/10T1/2 cells. Biomech Model Mechanobiol. 2005 Mar; 3(3):141-6. PMID: 15668766.
    View in: PubMed
  14. Zayzafoon M, Fulzele K, McDonald JM. Calmodulin and calmodulin-dependent kinase IIalpha regulate osteoblast differentiation by controlling c-fos expression. J Biol Chem. 2005 Feb 25; 280(8):7049-59. PMID: 15590632.
    View in: PubMed
  15. Datta D, Kundu PK, Dasgupta S, Fulzele K, Sewlikar S. Effect of addition of proton carriers in culture medium on growth and secretion of hybridoma cell line OKT3. Indian J Physiol Pharmacol. 2001 Jul; 45(3):367-72. PMID: 11881578.
    View in: PubMed
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