Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Mohamed Hassan Sayegh, M.D.

Co-Author

This page shows the publications co-authored by Mohamed Sayegh and Nader Najafian.
Connection Strength

2.978
  1. Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: potential novel assay for prediction of outcomes for renal transplant recipients. J Am Soc Nephrol. 2002 Jan; 13(1):252-259.
    View in: PubMed
    Score: 0.245
  2. T cell costimulatory blockade as a novel immune intervention in autoimmune diseases. Clin Dermatol. 2001 Sep-Oct; 19(5):586-91.
    View in: PubMed
    Score: 0.239
  3. CTLA4-Ig: a novel immunosuppressive agent. Expert Opin Investig Drugs. 2000 Sep; 9(9):2147-57.
    View in: PubMed
    Score: 0.223
  4. Targeting CD28 to prevent transplant rejection. Expert Opin Ther Targets. 2014 Feb; 18(2):225-42.
    View in: PubMed
    Score: 0.140
  5. Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses. Eur J Immunol. 2012 Sep; 42(9):2343-53.
    View in: PubMed
    Score: 0.128
  6. Immune profile of pediatric renal transplant recipients following alemtuzumab induction. J Am Soc Nephrol. 2012 Jan; 23(1):174-82.
    View in: PubMed
    Score: 0.121
  7. Role of nuclear factor of activated T cell (NFAT) transcription factors in skin and vascularized cardiac allograft rejection. Transplantation. 2011 Sep 15; 92(5):e26-7.
    View in: PubMed
    Score: 0.120
  8. Essential role of PDL1 expression on nonhematopoietic donor cells in acquired tolerance to vascularized cardiac allografts. Am J Transplant. 2011 Apr; 11(4):832-40.
    View in: PubMed
    Score: 0.116
  9. Immunosuppressive drugs and Tregs: a critical evaluation! Clin J Am Soc Nephrol. 2009 Oct; 4(10):1661-9.
    View in: PubMed
    Score: 0.104
  10. Negative T-cell costimulatory pathways: their role in regulating alloimmune responses. Curr Opin Organ Transplant. 2008 Aug; 13(4):373-8.
    View in: PubMed
    Score: 0.097
  11. The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest. 2008 Feb; 118(2):742-51.
    View in: PubMed
    Score: 0.093
  12. PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol. 2007 Oct 15; 179(8):5204-10.
    View in: PubMed
    Score: 0.091
  13. A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo. J Immunol. 2007 Jul 15; 179(2):786-96.
    View in: PubMed
    Score: 0.090
  14. A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells. J Am Soc Nephrol. 2006 Oct; 17(10):2844-53.
    View in: PubMed
    Score: 0.084
  15. Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo. J Immunol. 2005 Jun 01; 174(11):6648-56.
    View in: PubMed
    Score: 0.077
  16. Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo. J Immunol. 2005 Mar 15; 174(6):3408-15.
    View in: PubMed
    Score: 0.076
  17. CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo. J Immunol. 2005 Feb 01; 174(3):1357-64.
    View in: PubMed
    Score: 0.076
  18. Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. J Clin Invest. 2003 Oct; 112(7):1037-48.
    View in: PubMed
    Score: 0.069
  19. Regulatory CD25+ T cells in human kidney transplant recipients. J Am Soc Nephrol. 2003 Jun; 14(6):1643-51.
    View in: PubMed
    Score: 0.067
  20. The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo. J Immunol. 2003 Mar 15; 170(6):2949-55.
    View in: PubMed
    Score: 0.066
  21. New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs. Ann Surg. 2002 Nov; 236(5):667-75.
    View in: PubMed
    Score: 0.065
  22. Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25+ cells, and the alloreactive T cell clone size. J Immunol. 2002 Oct 01; 169(7):3744-51.
    View in: PubMed
    Score: 0.064
  23. The role of CC chemokine receptor 5 (CCR5) in islet allograft rejection. Diabetes. 2002 Aug; 51(8):2489-95.
    View in: PubMed
    Score: 0.064
  24. TNF:TNF-R T-Cell costimulatory pathways in transplantation. Transplant Proc. 2001 Nov-Dec; 33(7-8):3070-1.
    View in: PubMed
    Score: 0.060
  25. Physiologic regulation of alloimmune responses in vivo: the role of CTLA4 and TH1/TH2 cytokines. Transplant Proc. 2001 Nov-Dec; 33(7-8):3826-8.
    View in: PubMed
    Score: 0.060
  26. Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo. J Clin Invest. 2001 Apr; 107(7):909-16.
    View in: PubMed
    Score: 0.058
  27. Divergent Function of Programmed Death-Ligand 1 in Donor Tissue versus Recipient Immune System in a Murine Model of Bronchiolitis Obliterans. Am J Pathol. 2017 Jun; 187(6):1368-1379.
    View in: PubMed
    Score: 0.044
  28. In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity. J Clin Immunol. 2013 Jan; 33 Suppl 1:S43-9.
    View in: PubMed
    Score: 0.032
  29. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest. 2011 Sep; 121(9):3645-56.
    View in: PubMed
    Score: 0.030
  30. A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model. Transplantation. 2010 Aug 15; 90(3):260-9.
    View in: PubMed
    Score: 0.028
  31. A pilot study on the immunological effects of oral administration of donor major histocompatibility complex class II peptides in renal transplant recipients. Clin Transplant. 2008 Nov-Dec; 22(6):754-9.
    View in: PubMed
    Score: 0.024
  32. New insights in CD28-independent allograft rejection. Am J Transplant. 2007 Aug; 7(8):1917-26.
    View in: PubMed
    Score: 0.023
  33. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. J Exp Med. 2007 Jul 09; 204(7):1691-702.
    View in: PubMed
    Score: 0.022
  34. Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy. J Am Soc Nephrol. 2004 Jul; 15(7):1952-60.
    View in: PubMed
    Score: 0.018
  35. Differential role of CCR2 in islet and heart allograft rejection: tissue specificity of chemokine/chemokine receptor function in vivo. J Immunol. 2004 Jan 15; 172(2):767-75.
    View in: PubMed
    Score: 0.018
  36. Regulatory functions of alloreactive Th2 clones in human renal transplant recipients. Kidney Int. 2002 Aug; 62(2):627-31.
    View in: PubMed
    Score: 0.016
  37. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J Clin Invest. 2001 Sep; 108(5):739-47.
    View in: PubMed
    Score: 0.015
  38. CD28-independent induction of experimental autoimmune encephalomyelitis. J Clin Invest. 2001 Mar; 107(5):575-83.
    View in: PubMed
    Score: 0.014
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.