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Arjun Kumar Manrai, Ph.D.

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  1. K01HL138259 (MANRAI, ARJUN KUMAR) May 1, 2018 - Apr 30, 2023
    NIH/NHLBI
    Precision cardiovascular medicine for multi-ethnic populations
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Manrai AK, Ioannidis JPA, Patel CJ. Signals Among Signals: Prioritizing Nongenetic Associations in Massive Data Sets. Am J Epidemiol. 2019 May 01; 188(5):846-850. PMID: 30877292.
    Citations:    
  2. Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ. Author Correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nat Genet. 2019 04; 51(4):764-765. PMID: 30814726.
    Citations:    
  3. Mandl KD, Manrai AK. Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning. JAMA. 2019 Feb 08. PMID: 30735228.
    Citations:    
  4. Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ. Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nat Genet. 2019 02; 51(2):327-334. PMID: 30643253.
    Citations:    Fields:    
  5. Manrai AK, Patel CJ, Ioannidis JPA. Using Big Data to Determine Reference Values for Laboratory Tests-Reply. JAMA. 2018 10 09; 320(14):1496. PMID: 30304422.
    Citations:    Fields:    
  6. Manrai AK, Patel CJ, Ioannidis JPA. In the Era of Precision Medicine and Big Data, Who Is Normal? JAMA. 2018 May 15; 319(19):1981-1982. PMID: 29710130.
    Citations:    Fields:    Translation:Humans
  7. Diao JA, Kohane IS, Manrai AK. Biomedical informatics and machine learning for clinical genomics. Hum Mol Genet. 2018 05 01; 27(R1):R29-R34. PMID: 29566172.
    Citations:    Fields:    
  8. Kelly MA, Caleshu C, Morales A, Buchan J, Wolf Z, Harrison SM, Cook S, Dillon MW, Garcia J, Haverfield E, Jongbloed JDH, Macaya D, Manrai A, Orland K, Richard G, Spoonamore K, Thomas M, Thomson K, Vincent LM, Walsh R, Watkins H, Whiffin N, Ingles J, van Tintelen JP, Semsarian C, Ware JS, Hershberger R, Funke B. Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: recommendations by ClinGen's Inherited Cardiomyopathy Expert Panel. Genet Med. 2018 03; 20(3):351-359. PMID: 29300372.
    Citations: 11     Fields:    Translation:Humans
  9. Palmer N, Beam A, Agniel D, Eran A, Manrai A, Spettell C, Steinberg G, Mandl K, Fox K, Nelson SF, Kohane I. Association of Sex With Recurrence of Autism Spectrum Disorder Among Siblings. JAMA Pediatr. 2017 11 01; 171(11):1107-1112. PMID: 28973142.
    Citations: 2     Fields:    Translation:Humans
  10. Jasny BR, Wigginton N, McNutt M, Bubela T, Buck S, Cook-Deegan R, Gardner T, Hanson B, Hustad C, Kiermer V, Lazer D, Lupia A, Manrai A, McConnell L, Noonan K, Phimister E, Simon B, Strandburg K, Summers Z, Watts D. Fostering reproducibility in industry-academia research. Science. 2017 08 25; 357(6353):759-761. PMID: 28839064.
    Citations:    Fields:    
  11. Patel CJ, Manrai AK, Corona E, Kohane IS. Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length. Int J Epidemiol. 2017 02 01; 46(1):44-56. PMID: 27059547.
    Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
  12. Karczewski KJ, Tatonetti NP, Manrai AK, Patel CJ, Titus Brown C, Ioannidis JPA. METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH. Pac Symp Biocomput. 2017; 22:117-119. PMID: 27896967.
    Citations: 1     Fields:    
  13. Manrai AK, Cui Y, Bushel PR, Hall M, Karakitsios S, Mattingly CJ, Ritchie M, Schmitt C, Sarigiannis DA, Thomas DC, Wishart D, Balshaw DM, Patel CJ. Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health. Annu Rev Public Health. 2017 Mar 20; 38:279-294. PMID: 28068484.
    Citations:    
  14. Manrai AK, Funke BH, Rehm HL, Olesen MS, Maron BA, Szolovits P, Margulies DM, Loscalzo J, Kohane IS. Genetic Misdiagnoses and the Potential for Health Disparities. N Engl J Med. 2016 Aug 18; 375(7):655-65. PMID: 27532831.
    Citations: 68     Fields:    Translation:Humans
  15. Manrai AK, Ioannidis JP, Kohane IS. Clinical Genomics: From Pathogenicity Claims to Quantitative Risk Estimates. JAMA. 2016 Mar 22-29; 315(12):1233-4. PMID: 26925924.
    Citations: 11     Fields:    Translation:Humans
  16. Manrai AK, Wang BL, Patel CJ, Kohane IS. REPRODUCIBLE AND SHAREABLE QUANTIFICATIONS OF PATHOGENICITY. Pac Symp Biocomput. 2016; 21:231-42. PMID: 26776189.
    Citations: 2     Fields:    Translation:Humans
  17. Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS. METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE. Pac Symp Biocomput. 2016; 21:180-2. PMID: 26776184.
    Citations:    
  18. Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS. METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE. Pac Symp Biocomput. 2016; 21:180-182. PMID: 28004011.
    Citations: 1     Fields:    Translation:Humans
  19. Patel CJ, Manrai AK. Development of exposome correlation globes to map out environment-wide associations. Pac Symp Biocomput. 2015; 231-42. PMID: 25592584.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  20. Manrai AK, Bhatia G, Strymish J, Kohane IS, Jain SH. Medicine's uncomfortable relationship with math: calculating positive predictive value. JAMA Intern Med. 2014 Jun; 174(6):991-3. PMID: 24756486.
    Citations: 8     Fields:    Translation:Humans
  21. Milwid JM, Elman JS, Li M, Shen K, Manrai A, Gabow A, Yarmush J, Jiao Y, Fletcher A, Lee J, Cima MJ, Yarmush ML, Parekkadan B. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators. Mol Ther. 2014 May; 22(5):999-1007. PMID: 24496384.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  22. Manrai AK, Kohane IS, Szolovits P. Urinary-cell mRNA and acute kidney-transplant rejection. N Engl J Med. 2013 11 07; 369(19):1859. PMID: 24195557.
    Citations:    Fields:    Translation:Humans
  23. Shin H, Liu T, Manrai AK, Liu XS. CEAS: cis-regulatory element annotation system. Bioinformatics. 2009 Oct 01; 25(19):2605-6. PMID: 19689956.
    Citations: 208     Fields:    Translation:Cells
  24. Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, Jänne OA, Balk SP, Mehra R, Han B, Chinnaiyan AM, Rubin MA, True L, Fiorentino M, Fiore C, Loda M, Kantoff PW, Liu XS, Brown M. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 2009 Jul 23; 138(2):245-56. PMID: 19632176.
    Citations: 352     Fields:    Translation:HumansCells
  25. Manrai AK, Gunawardena J. The geometry of multisite phosphorylation. Biophys J. 2008 Dec 15; 95(12):5533-43. PMID: 18849417.
    Citations: 12     Fields:    Translation:Cells
  26. Song JS, Johnson WE, Zhu X, Zhang X, Li W, Manrai AK, Liu JS, Chen R, Liu XS. Model-based analysis of two-color arrays (MA2C). Genome Biol. 2007; 8(8):R178. PMID: 17727723.
    Citations: 71     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.