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Steven James Skates, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01CA260758 (SKATES, STEVEN J) Sep 15, 2021 - Aug 31, 2026
    Proteomic Analyses of Serial Prediagnostic PLCO Serum in Cases and Controls to Identify Early Detection Ovarian Cancer Biomarkers Rising in a Substantial Fraction of Cases and Stable in Most Controls
    Role: Principal Investigator
  2. R01CA247220 (LOKSHIN, ANNA E) Sep 1, 2020 - May 31, 2025
    Development of Novel Ovarian Cancer Biomarkers for Early Detection Algorithms
    Role: Co-Principal Investigator
  3. U01CA152990 (SKATES, STEVEN J) Sep 24, 2010 - Mar 31, 2022
    Proteomic, Genomic, and Longitudinal Pathways to Ovarian Cancer Biomarker Discovery
    Role: Co-Principal Investigator
  4. P50CA105009 (CRAMER, DANIEL WILLIAM) Aug 1, 2004 - Jul 31, 2012
    Dana-Farber/Harvard Cancer Center Ovarian Cancer SPORE
    Role: Co-Principal Investigator
  5. R03CA073922 (SKATES, STEVEN J) Sep 30, 1997 - Mar 29, 2000
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Philpott S, Raikou M, Manchanda R, Lockley M, Singh N, Scott M, Evans DG, Adlard J, Ahmed M, Edmondson R, Woodward ER, Lamnisos A, Balega J, Brady AF, Sharma A, Izatt L, Kulkarni A, Tripathi V, Solomons JS, Hayes K, Hanson H, Snape K, Side L, Skates S, McGuire A, Rosenthal AN. The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1 and BRCA2. J Med Genet. 2022 Nov 01. PMID: 36319079.
    Citations:    Fields:    
  2. Kennedy JJ, Whiteaker JR, Ivey RG, Burian A, Chowdhury S, Tsai CF, Liu T, Lin C, Murillo OD, Lundeen RA, Jones LA, Gafken PR, Longton G, Rodland KD, Skates SJ, Landua J, Wang P, Lewis MT, Paulovich AG. Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma. Anal Chem. 2022 07 12; 94(27):9540-9547. PMID: 35767427; PMCID: PMC9280723.
    Citations:    Fields:    Translation:Humans
  3. Raoof S, Lee RJ, Jajoo K, Mancias JD, Rebbeck TR, Skates SJ. Multicancer Early Detection Technologies: A Review Informed by Past Cancer Screening Studies. Cancer Epidemiol Biomarkers Prev. 2022 06 01; 31(6):1139-1145. PMID: 35320352.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  4. Putcha G, Gutierrez A, Skates S. Multicancer Screening: One Size Does Not Fit All. JCO Precis Oncol. 2021 11; 5:574-576. PMID: 34994606.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  5. Lopez L, Nguyen T, Weber G, Kleimola K, Bereda M, Liu Y, Accorsi EK, Skates SJ, Santa Maria JP, Smith KR, Kalinich M. Seroprevalence of anti-SARS-CoV-2 IgG antibodies in the staff of a public school system in the midwestern United States. PLoS One. 2021; 16(6):e0243676. PMID: 34111144.
    Citations: 7     Fields:    Translation:HumansCells
  6. Menon U, Gentry-Maharaj A, Burnell M, Singh N, Ryan A, Karpinskyj C, Carlino G, Taylor J, Massingham SK, Raikou M, Kalsi JK, Woolas R, Manchanda R, Arora R, Casey L, Dawnay A, Dobbs S, Leeson S, Mould T, Seif MW, Sharma A, Williamson K, Liu Y, Fallowfield L, McGuire AJ, Campbell S, Skates SJ, Jacobs IJ, Parmar M. Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial. Lancet. 2021 06 05; 397(10290):2182-2193. PMID: 33991479.
    Citations: 48     Fields:    Translation:Humans
  7. Burnell M, Gentry-Maharaj A, Skates SJ, Ryan A, Karpinskyj C, Kalsi J, Apostolidou S, Singh N, Dawnay A, Woolas R, Fallowfield L, Campbell S, McGuire A, Jacobs IJ, Parmar M, Menon U. UKCTOCS update: applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis. Trials. 2021 Mar 01; 22(1):173. PMID: 33648562; PMCID: PMC7919310.
    Citations: 1     Fields:    Translation:Humans
  8. Kalsi J, Gentry-Maharaj A, Ryan A, Singh N, Burnell M, Massingham S, Apostolidou S, Sharma A, Williamson K, Seif M, Mould T, Woolas R, Dobbs S, Leeson S, Fallowfield L, Skates SJ, Parmar M, Campbell S, Jacobs I, McGuire A, Menon U. Performance Characteristics of the Ultrasound Strategy during Incidence Screening in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Cancers (Basel). 2021 Feb 18; 13(4). PMID: 33670571; PMCID: PMC7922843.
    Citations: 1     
  9. Sequist LV, Skates SJ, Haas W. A New Era of Protein-Based Assays for Cancer Early Detection. J Thorac Oncol. 2021 02; 16(2):191-193. PMID: 33494925.
    Citations:    Fields:    Translation:Humans
  10. Kalsi JK, Ryan A, Gentry-Maharaj A, Margolin-Crump D, Singh N, Burnell M, Benjamin E, Apostolidou S, Habib M, Massingham S, Karpinskyj C, Woolas R, Widschwendter M, Fallowfield L, Campbell S, Skates S, McGuire A, Parmar M, Jacobs I, Menon U. Completeness and accuracy of national cancer and death registration for outcome ascertainment in trials-an ovarian cancer exemplar. Trials. 2021 Jan 25; 22(1):88. PMID: 33494753; PMCID: PMC7831170.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  11. Blackman A, Mitchell J, Rowswell-Turner R, Singh R, Kim KK, Eklund E, Skates S, Bast RC, Messerlian G, Miller MC, Moore RG. Analysis of serum HE4 levels in various histologic subtypes of epithelial ovarian cancer and other malignant tumors. Tumour Biol. 2021; 43(1):355-365. PMID: 34957977.
    Citations:    Fields:    Translation:Humans
  12. Lopez L, Nguyen T, Weber G, Kleimola K, Bereda M, Liu Y, Accorsi EK, Skates SJ, Santa Maria JP, Smith KR, Kalinich M. Seroprevalence of anti-SARS-CoV-2 IgG Antibodies in the Staff of a Public School System in the Midwestern United States. medRxiv. 2020 Oct 27. PMID: 33140066; PMCID: PMC7605578.
  13. Bast RC, Lu Z, Han CY, Lu KH, Anderson KS, Drescher CW, Skates SJ. Biomarkers and Strategies for Early Detection of Ovarian Cancer. Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2504-2512. PMID: 33051337.
    Citations: 18     Fields:    Translation:HumansCells
  14. Lentz SE, Powell CB, Haque R, Armstrong MA, Anderson M, Liu Y, Jiang W, Chillemi G, Shaw S, Alvarado MM, Kushi LH, Skates SJ. Development of a longitudinal two-biomarker algorithm for early detection of ovarian cancer in women with BRCA mutations. Gynecol Oncol. 2020 12; 159(3):804-810. PMID: 33012551.
    Citations: 1     Fields:    Translation:Humans
  15. Gentry-Maharaj A, Blyuss O, Ryan A, Burnell M, Karpinskyj C, Gunu R, Kalsi JK, Dawnay A, Marino IP, Manchanda R, Lu K, Yang WL, Timms JF, Parmar M, Skates SJ, Bast RC, Jacobs IJ, Zaikin A, Menon U. Multi-Marker Longitudinal Algorithms Incorporating HE4 and CA125 in Ovarian Cancer Screening of Postmenopausal Women. Cancers (Basel). 2020 Jul 17; 12(7). PMID: 32708856.
    Citations: 4     
  16. Dilley J, Burnell M, Gentry-Maharaj A, Ryan A, Neophytou C, Apostolidou S, Karpinskyj C, Kalsi J, Mould T, Woolas R, Singh N, Widschwendter M, Fallowfield L, Campbell S, Skates SJ, McGuire A, Parmar M, Jacobs I, Menon U. Ovarian cancer symptoms, routes to diagnosis and survival - Population cohort study in the 'no screen' arm of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Gynecol Oncol. 2020 08; 158(2):316-322. PMID: 32561125.
    Citations: 6     Fields:    Translation:Humans
  17. Haque R, Skates SJ, Armstrong MA, Lentz SE, Anderson M, Jiang W, Alvarado MM, Chillemi G, Shaw SF, Kushi LH, Powell CB. Feasibility, patient compliance and acceptability of ovarian cancer surveillance using two serum biomarkers and Risk of Ovarian Cancer Algorithm compared to standard ultrasound and CA 125 among women with BRCA mutations. Gynecol Oncol. 2020 05; 157(2):521-528. PMID: 32145911.
    Citations: 2     Fields:    Translation:Humans
  18. Yang WL, Lu Z, Guo J, Fellman BM, Ning J, Lu KH, Menon U, Kobayashi M, Hanash SM, Celestino J, Skates SJ, Bast RC. Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer. Cancer. 2020 02 15; 126(4):725-736. PMID: 31714597; PMCID: PMC6992519.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  19. Mai PL, Miller A, Gail MH, Skates S, Lu K, Sherman ME, Ioffe OB, Rodriguez G, Cohn DE, Boggess J, Rutherford T, Kauff ND, Rader JS, Phillips KA, DiSilvestro PA, Olawaiye AB, Ridgway MR, Greene MH, Piedmonte M, Walker JL. Risk-Reducing Salpingo-Oophorectomy and Breast Cancer Risk Reduction in the Gynecologic Oncology Group Protocol-0199 (GOG-0199). JNCI Cancer Spectr. 2020 Feb; 4(1):pkz075. PMID: 32337492; PMCID: PMC7050151.
    Citations: 1     Fields:    
  20. Simmons AR, Fourkala EO, Gentry-Maharaj A, Ryan A, Sutton MN, Baggerly K, Zheng H, Lu KH, Jacobs I, Skates S, Menon U, Bast RC. Complementary Longitudinal Serum Biomarkers to CA125 for Early Detection of Ovarian Cancer. Cancer Prev Res (Phila). 2019 06; 12(6):391-400. PMID: 30967390.
    Citations: 7     Fields:    Translation:Humans
  21. Blyuss O, Burnell M, Ryan A, Gentry-Maharaj A, Mariño IP, Kalsi J, Manchanda R, Timms JF, Parmar M, Skates SJ, Jacobs I, Zaikin A, Menon U. Comparison of Longitudinal CA125 Algorithms as a First-Line Screen for Ovarian Cancer in the General Population. Clin Cancer Res. 2018 10 01; 24(19):4726-4733. PMID: 30084833.
    Citations: 14     Fields:    Translation:Humans
  22. Stott W, Campbell S, Franchini A, Blyuss O, Zaikin A, Ryan A, Jones C, Gentry-Maharaj A, Fletcher G, Kalsi J, Skates S, Parmar M, Amso N, Jacobs I, Menon U. Sonographers' self-reported visualization of normal postmenopausal ovaries on transvaginal ultrasound is not reliable: results of expert review of archived images from UKCTOCS. Ultrasound Obstet Gynecol. 2018 03; 51(3):401-408. PMID: 28796383.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  23. Menon U, McGuire AJ, Raikou M, Ryan A, Davies SK, Burnell M, Gentry-Maharaj A, Kalsi JK, Singh N, Amso NN, Cruickshank D, Dobbs S, Godfrey K, Herod J, Leeson S, Mould T, Murdoch J, Oram D, Scott I, Seif MW, Williamson K, Woolas R, Fallowfield L, Campbell S, Skates SJ, Parmar M, Jacobs IJ. The cost-effectiveness of screening for ovarian cancer: results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Br J Cancer. 2017 Aug 22; 117(5):619-627. PMID: 28742794; PMCID: PMC5572177.
    Citations: 7     Fields:    Translation:Humans
  24. Yang WL, Gentry-Maharaj A, Simmons A, Ryan A, Fourkala EO, Lu Z, Baggerly KA, Zhao Y, Lu KH, Bowtell D, Jacobs I, Skates SJ, He WW, Menon U, Bast RC. Elevation of TP53 Autoantibody Before CA125 in Preclinical Invasive Epithelial Ovarian Cancer. Clin Cancer Res. 2017 Oct 01; 23(19):5912-5922. PMID: 28637689; PMCID: PMC5626590.
    Citations: 29     Fields:    Translation:Humans
  25. Gentry-Maharaj A, Glazer C, Burnell M, Ryan A, Berry H, Kalsi J, Woolas R, Skates SJ, Campbell S, Parmar M, Jacobs I, Menon U. Changing trends in reproductive/lifestyle factors in UK women: descriptive study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ Open. 2017 03 06; 7(3):e011822. PMID: 28264823.
    Citations: 4     Fields:    Translation:Humans
  26. Rosenthal AN, Fraser LSM, Philpott S, Manchanda R, Burnell M, Badman P, Hadwin R, Rizzuto I, Benjamin E, Singh N, Evans DG, Eccles DM, Ryan A, Liston R, Dawnay A, Ford J, Gunu R, Mackay J, Skates SJ, Menon U, Jacobs IJ. Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study. J Clin Oncol. 2017 May 01; 35(13):1411-1420. PMID: 28240969; PMCID: PMC5455461.
    Citations: 48     Fields:    Translation:Humans
  27. Skates SJ, Greene MH, Buys SS, Mai PL, Brown P, Piedmonte M, Rodriguez G, Schorge JO, Sherman M, Daly MB, Rutherford T, Brewster WR, O'Malley DM, Partridge E, Boggess J, Drescher CW, Isaacs C, Berchuck A, Domchek S, Davidson SA, Edwards R, Elg SA, Wakeley K, Phillips KA, Armstrong D, Horowitz I, Fabian CJ, Walker J, Sluss PM, Welch W, Minasian L, Horick NK, Kasten CH, Nayfield S, Alberts D, Finkelstein DM, Lu KH. Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk - Combined Results from Two Screening Trials. Clin Cancer Res. 2017 Jul 15; 23(14):3628-3637. PMID: 28143870; PMCID: PMC5726402.
    Citations: 32     Fields:    Translation:Humans
  28. Skates SJ. EPIC Early Detection of Ovarian Cancer. Clin Cancer Res. 2016 Sep 15; 22(18):4542-4. PMID: 27418634; PMCID: PMC5026579.
    Citations: 2     Fields:    Translation:Humans
  29. Simmons AR, Clarke CH, Badgwell DB, Lu Z, Sokoll LJ, Lu KH, Zhang Z, Bast RC, Skates SJ. Validation of a Biomarker Panel and Longitudinal Biomarker Performance for Early Detection of Ovarian Cancer. Int J Gynecol Cancer. 2016 07; 26(6):1070-7. PMID: 27206285; PMCID: PMC4915986.
    Citations: 20     Fields:    Translation:Humans
  30. Jacobs IJ, Parmar M, Skates SJ, Menon U. Ovarian cancer screening: UKCTOCS trial - Authors' reply. Lancet. 2016 Jun 25; 387(10038):2603-2604. PMID: 27353822.
    Citations: 4     Fields:    Translation:Humans
  31. Anderson L, Razavi M, Skates S, Anderson NG, Pearson TW. Squeezing more value from the analytes we have: personal baselines for multiple analytes in serial DBS. Bioanalysis. 2016 Aug; 8(15):1539-1542. PMID: 27277878.
    Citations: 2     Fields:    Translation:HumansAnimals
  32. Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, Gatza ML, Wilkerson M, Perou CM, Yellapantula V, Huang KL, Lin C, McLellan MD, Yan P, Davies SR, Townsend RR, Skates SJ, Wang J, Zhang B, Kinsinger CR, Mesri M, Rodriguez H, Ding L, Paulovich AG, Fenyö D, Ellis MJ, Carr SA. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 2016 06 02; 534(7605):55-62. PMID: 27251275; PMCID: PMC5102256.
    Citations: 618     Fields:    Translation:HumansCells
  33. Russell MR, Walker MJ, Williamson AJ, Gentry-Maharaj A, Ryan A, Kalsi J, Skates S, D'Amato A, Dive C, Pernemalm M, Humphryes PC, Fourkala EO, Whetton AD, Menon U, Jacobs I, Graham RL. Protein Z: A putative novel biomarker for early detection of ovarian cancer. Int J Cancer. 2016 Jun 15; 138(12):2984-92. PMID: 26815306.
    Citations: 18     Fields:    Translation:Humans
  34. Jacobs IJ, Menon U, Ryan A, Gentry-Maharaj A, Burnell M, Kalsi JK, Amso NN, Apostolidou S, Benjamin E, Cruickshank D, Crump DN, Davies SK, Dawnay A, Dobbs S, Fletcher G, Ford J, Godfrey K, Gunu R, Habib M, Hallett R, Herod J, Jenkins H, Karpinskyj C, Leeson S, Lewis SJ, Liston WR, Lopes A, Mould T, Murdoch J, Oram D, Rabideau DJ, Reynolds K, Scott I, Seif MW, Sharma A, Singh N, Taylor J, Warburton F, Widschwendter M, Williamson K, Woolas R, Fallowfield L, McGuire AJ, Campbell S, Parmar M, Skates SJ. Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial. Lancet. 2016 Mar 05; 387(10022):945-956. PMID: 26707054; PMCID: PMC4779792.
    Citations: 311     Fields:    Translation:Humans
  35. Menon U, Kalsi JK, Gentry-Maharaj A, Ryan A, Burnell M, Parmar M, Fallowfield L, Campbell S, McGuire A, Skates S, Jacobs I. Reply to P.F. Pinsky, C.P. Crum, and M.W. McIntosh et al. J Clin Oncol. 2016 Jan 10; 34(2):201-2. PMID: 26573079.
    Citations:    Fields:    Translation:Humans
  36. Menon U, Ryan A, Kalsi J, Gentry-Maharaj A, Dawnay A, Habib M, Apostolidou S, Singh N, Benjamin E, Burnell M, Davies S, Sharma A, Gunu R, Godfrey K, Lopes A, Oram D, Herod J, Williamson K, Seif MW, Jenkins H, Mould T, Woolas R, Murdoch JB, Dobbs S, Amso NN, Leeson S, Cruickshank D, Scott I, Fallowfield L, Widschwendter M, Reynolds K, McGuire A, Campbell S, Parmar M, Skates SJ, Jacobs I. Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening. J Clin Oncol. 2015 Jun 20; 33(18):2062-71. PMID: 25964255.
    Citations: 65     Fields:    Translation:HumansPHPublic Health
  37. Vathipadiekal V, Wang V, Wei W, Waldron L, Drapkin R, Gillette M, Skates S, Birrer M. Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array. Clin Cancer Res. 2015 Nov 01; 21(21):4960-9. PMID: 25944803.
    Citations: 35     Fields:    Translation:HumansCells
  38. Schully SD, Carrick DM, Mechanic LE, Srivastava S, Anderson GL, Baron JA, Berg CD, Cullen J, Diamandis EP, Doria-Rose VP, Goddard KA, Hankinson SE, Kushi LH, Larson EB, McShane LM, Schilsky RL, Shak S, Skates SJ, Urban N, Kramer BS, Khoury MJ, Ransohoff DF. Leveraging biospecimen resources for discovery or validation of markers for early cancer detection. J Natl Cancer Inst. 2015 Apr; 107(4). PMID: 25688116; PMCID: PMC4342676.
    Citations: 13     Fields:    Translation:Humans
  39. Menon U, Talaat A, Rosenthal AN, Macdonald ND, Jeyerajah AR, Skates SJ, Sibley K, Oram DH, Jacobs IJ. Performance of ultrasound as a second line test to serum CA125 in ovarian cancer screening. BJOG. 2014 Dec; 121 Suppl 7:35-9. PMID: 25488086.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  40. Creaney J, Segal A, Olsen N, Dick IM, Musk AW, Skates SJ, Robinson BW. Pleural fluid mesothelin as an adjunct to the diagnosis of pleural malignant mesothelioma. Dis Markers. 2014; 2014:413946. PMID: 25505814; PMCID: PMC4258360.
    Citations: 8     Fields:    Translation:Humans
  41. Moore RG, Hawkins DM, Miller MC, Landrum LM, Gajewski W, Ball JJ, Allard WJ, Skates SJ. Combining clinical assessment and the Risk of Ovarian Malignancy Algorithm for the prediction of ovarian cancer. Gynecol Oncol. 2014 Dec; 135(3):547-51. PMID: 25449569.
    Citations: 4     Fields:    Translation:Humans
  42. Sherman ME, Piedmonte M, Mai PL, Ioffe OB, Ronnett BM, Van Le L, Ivanov I, Bell MC, Blank SV, DiSilvestro P, Hamilton CA, Tewari KS, Wakeley K, Kauff ND, Yamada SD, Rodriguez G, Skates SJ, Alberts DS, Walker JL, Minasian L, Lu K, Greene MH. Pathologic findings at risk-reducing salpingo-oophorectomy: primary results from Gynecologic Oncology Group Trial GOG-0199. J Clin Oncol. 2014 Oct 10; 32(29):3275-83. PMID: 25199754.
    Citations: 31     Fields:    Translation:HumansCTClinical Trials
  43. Creaney J, Dick IM, Meniawy TM, Leong SL, Leon JS, Demelker Y, Segal A, Musk AW, Lee YC, Skates SJ, Nowak AK, Robinson BW. Comparison of fibulin-3 and mesothelin as markers in malignant mesothelioma. Thorax. 2014 Oct; 69(10):895-902. PMID: 25037982; PMCID: PMC4174124.
    Citations: 50     Fields:    Translation:Humans
  44. Skates SJ. A statistical challenge: developing tests for biomarker utility specific to the intended use. J Natl Cancer Inst. 2014 Apr; 106(4):dju076. PMID: 24681600.
    Citations: 1     Fields:    Translation:Humans
  45. Holman LL, Lu KH, Bast RC, Hernandez MA, Bodurka DC, Skates S, Sun CC. Risk perception, worry, and test acceptance in average-risk women who undergo ovarian cancer screening. Am J Obstet Gynecol. 2014 Mar; 210(3):257.e1-6. PMID: 24246524; PMCID: PMC4001707.
    Citations: 4     Fields:    Translation:Humans
  46. Skates SJ, Gillette MA, LaBaer J, Carr SA, Anderson L, Liebler DC, Ransohoff D, Rifai N, Kondratovich M, Težak Ž, Mansfield E, Oberg AL, Wright I, Barnes G, Gail M, Mesri M, Kinsinger CR, Rodriguez H, Boja ES. Statistical design for biospecimen cohort size in proteomics-based biomarker discovery and verification studies. J Proteome Res. 2013 Dec 06; 12(12):5383-94. PMID: 24063748.
    Citations: 47     Fields:    Translation:Humans
  47. Lu KH, Skates S, Hernandez MA, Bedi D, Bevers T, Leeds L, Moore R, Granai C, Harris S, Newland W, Adeyinka O, Geffen J, Deavers MT, Sun CC, Horick N, Fritsche H, Bast RC. A 2-stage ovarian cancer screening strategy using the Risk of Ovarian Cancer Algorithm (ROCA) identifies early-stage incident cancers and demonstrates high positive predictive value. Cancer. 2013 Oct 01; 119(19):3454-61. PMID: 23983047; PMCID: PMC3982191.
    Citations: 52     Fields:    Translation:Humans
  48. Creaney J, Sneddon S, Dick IM, Dare H, Boudville N, Musk AW, Skates SJ, Robinson BW. Comparison of the diagnostic accuracy of the MSLN gene products, mesothelin and megakaryocyte potentiating factor, as biomarkers for mesothelioma in pleural effusions and serum. Dis Markers. 2013; 35(2):119-27. PMID: 24167356; PMCID: PMC3774973.
    Citations: 18     Fields:    Translation:Humans
  49. Abbatiello SE, Mani DR, Schilling B, Maclean B, Zimmerman LJ, Feng X, Cusack MP, Sedransk N, Hall SC, Addona T, Allen S, Dodder NG, Ghosh M, Held JM, Hedrick V, Inerowicz HD, Jackson A, Keshishian H, Kim JW, Lyssand JS, Riley CP, Rudnick P, Sadowski P, Shaddox K, Smith D, Tomazela D, Wahlander A, Waldemarson S, Whitwell CA, You J, Zhang S, Kinsinger CR, Mesri M, Rodriguez H, Borchers CH, Buck C, Fisher SJ, Gibson BW, Liebler D, Maccoss M, Neubert TA, Paulovich A, Regnier F, Skates SJ, Tempst P, Wang M, Carr SA. Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in liquid chromatography-multiple reaction monitoring-MS (LC-MRM-MS). Mol Cell Proteomics. 2013 Sep; 12(9):2623-39. PMID: 23689285.
    Citations: 44     Fields:    Translation:AnimalsCells
  50. Rosenthal AN, Fraser L, Manchanda R, Badman P, Philpott S, Mozersky J, Hadwin R, Cafferty FH, Benjamin E, Singh N, Evans DG, Eccles DM, Skates SJ, Mackay J, Menon U, Jacobs IJ. Results of annual screening in phase I of the United Kingdom familial ovarian cancer screening study highlight the need for strict adherence to screening schedule. J Clin Oncol. 2013 Jan 01; 31(1):49-57. PMID: 23213100.
    Citations: 41     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  51. Pinsky PF, Zhu C, Skates SJ, Black A, Partridge E, Buys SS, Berg CD. Potential effect of the risk of ovarian cancer algorithm (ROCA) on the mortality outcome of the Prostate, Lung, Colorectal and Ovarian (PLCO) trial. Int J Cancer. 2013 May 01; 132(9):2127-33. PMID: 23065684.
    Citations: 16     Fields:    Translation:Humans
  52. Skates SJ. Ovarian cancer screening: development of the risk of ovarian cancer algorithm (ROCA) and ROCA screening trials. Int J Gynecol Cancer. 2012 May; 22 Suppl 1:S24-6. PMID: 22543916.
    Citations: 36     Fields:    Translation:Humans
  53. Bast RC, Skates S, Lokshin A, Moore RG. Differential diagnosis of a pelvic mass: improved algorithms and novel biomarkers. Int J Gynecol Cancer. 2012 May; 22 Suppl 1:S5-8. PMID: 22543921.
    Citations: 30     Fields:    Translation:Humans
  54. Menon U, Kalsi J, Jacobs I, Manchanda R, Beller U, Mould T, Skates S, Lokshin A. International Conference on Ovarian Cancer Screening: 29th-30th November 2011, Royal College of Physicians, London. Foreword. Int J Gynecol Cancer. 2012 May; 22 Suppl 1:S1. PMID: 22543910.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  55. Moore RG, Miller MC, Steinhoff MM, Skates SJ, Lu KH, Lambert-Messerlian G, Bast RC. Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders. Am J Obstet Gynecol. 2012 Apr; 206(4):351.e1-8. PMID: 22284961; PMCID: PMC3985608.
    Citations: 50     Fields:    Translation:Humans
  56. Kuhn E, Whiteaker JR, Mani DR, Jackson AM, Zhao L, Pope ME, Smith D, Rivera KD, Anderson NL, Skates SJ, Pearson TW, Paulovich AG, Carr SA. Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma. Mol Cell Proteomics. 2012 Jun; 11(6):M111.013854. PMID: 22199228.
    Citations: 63     Fields:    Translation:HumansAnimals
  57. Skates SJ, Mai P, Horick NK, Piedmonte M, Drescher CW, Isaacs C, Armstrong DK, Buys SS, Rodriguez GC, Horowitz IR, Berchuck A, Daly MB, Domchek S, Cohn DE, Van Le L, Schorge JO, Newland W, Davidson SA, Barnes M, Brewster W, Azodi M, Nerenstone S, Kauff ND, Fabian CJ, Sluss PM, Nayfield SG, Kasten CH, Finkelstein DM, Greene MH, Lu K. Large prospective study of ovarian cancer screening in high-risk women: CA125 cut-point defined by menopausal status. Cancer Prev Res (Phila). 2011 Sep; 4(9):1401-8. PMID: 21893500; PMCID: PMC3172691.
    Citations: 25     Fields:    Translation:Humans
  58. Moore RG, Miller MC, Disilvestro P, Landrum LM, Gajewski W, Ball JJ, Skates SJ. Evaluation of the diagnostic accuracy of the risk of ovarian malignancy algorithm in women with a pelvic mass. Obstet Gynecol. 2011 Aug; 118(2 Pt 1):280-288. PMID: 21775843; PMCID: PMC3594110.
    Citations: 79     Fields:    Translation:HumansCTClinical Trials
  59. Zhang Z, Skates SJ, Sokoll LJ, Lu Z, Clarke CH, Hernandez MA, Lu KH, Bast RC. A multivariate longitudinal algorithm for early detection of ovarian cancer using multiple biomarkers. J Clin Oncol. 2011 May 20; 29(15_suppl):5031. PMID: 28023709.
  60. Creaney J, Yeoman D, Musk AW, de Klerk N, Skates SJ, Robinson BW. Plasma versus serum levels of osteopontin and mesothelin in patients with malignant mesothelioma--which is best? Lung Cancer. 2011 Oct; 74(1):55-60. PMID: 21397972.
    Citations: 20     Fields:    Translation:Humans
  61. Burnell M, Gentry-Maharaj A, Ryan A, Apostolidou S, Habib M, Kalsi J, Skates S, Parmar M, Seif MW, Amso NN, Godfrey K, Oram D, Herod J, Williamson K, Jenkins H, Mould T, Woolas R, Murdoch J, Dobbs S, Leeson S, Cruickshank D, Campbell S, Fallowfield L, Jacobs I, Menon U. Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials. Trials. 2011 Mar 01; 12:61. PMID: 21362184; PMCID: PMC3058013.
    Citations: 22     Fields:    Translation:HumansPHPublic Health
  62. Cramer DW, Bast RC, Berg CD, Diamandis EP, Godwin AK, Hartge P, Lokshin AE, Lu KH, McIntosh MW, Mor G, Patriotis C, Pinsky PF, Thornquist MD, Scholler N, Skates SJ, Sluss PM, Srivastava S, Ward DC, Zhang Z, Zhu CS, Urban N. Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prev Res (Phila). 2011 Mar; 4(3):365-74. PMID: 21372036.
    Citations: 124     Fields:    Translation:Humans
  63. Zhu CS, Pinsky PF, Cramer DW, Ransohoff DF, Hartge P, Pfeiffer RM, Urban N, Mor G, Bast RC, Moore LE, Lokshin AE, McIntosh MW, Skates SJ, Vitonis A, Zhang Z, Ward DC, Symanowski JT, Lomakin A, Fung ET, Sluss PM, Scholler N, Lu KH, Marrangoni AM, Patriotis C, Srivastava S, Buys SS, Berg CD. A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer. Cancer Prev Res (Phila). 2011 Mar; 4(3):375-83. PMID: 21372037.
    Citations: 82     Fields:    Translation:Humans
  64. Jacobs I, Gentry-Maharaj A, Burnell M, Manchanda R, Singh N, Sharma A, Ryan A, Seif MW, Amso NN, Turner G, Brunell C, Fletcher G, Rangar R, Ford K, Godfrey K, Lopes A, Oram D, Herod J, Williamson K, Scott I, Jenkins H, Mould T, Woolas R, Murdoch J, Dobbs S, Leeson S, Cruickshank D, Skates SJ, Fallowfield L, Parmar M, Campbell S, Menon U. Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort. Lancet Oncol. 2011 Jan; 12(1):38-48. PMID: 21147030.
    Citations: 44     Fields:    Translation:Humans
  65. Creaney J, Olsen NJ, Brims F, Dick IM, Musk AW, de Klerk NH, Skates SJ, Robinson BW. Serum mesothelin for early detection of asbestos-induced cancer malignant mesothelioma. Cancer Epidemiol Biomarkers Prev. 2010 Sep; 19(9):2238-46. PMID: 20651076.
    Citations: 29     Fields:    Translation:Humans
  66. Moore RG, Jabre-Raughley M, Brown AK, Robison KM, Miller MC, Allard WJ, Kurman RJ, Bast RC, Skates SJ. Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic mass. Am J Obstet Gynecol. 2010 Sep; 203(3):228.e1-6. PMID: 20471625; PMCID: PMC3594101.
    Citations: 96     Fields:    Translation:HumansCTClinical Trials
  67. Yurkovetsky Z, Skates S, Lomakin A, Nolen B, Pulsipher T, Modugno F, Marks J, Godwin A, Gorelik E, Jacobs I, Menon U, Lu K, Badgwell D, Bast RC, Lokshin AE. Development of a multimarker assay for early detection of ovarian cancer. J Clin Oncol. 2010 May 01; 28(13):2159-66. PMID: 20368574.
    Citations: 102     Fields:    Translation:HumansPHPublic Health
  68. Rodriguez H, Tezak Z, Mesri M, Carr SA, Liebler DC, Fisher SJ, Tempst P, Hiltke T, Kessler LG, Kinsinger CR, Philip R, Ransohoff DF, Skates SJ, Regnier FE, Anderson NL, Mansfield E. Analytical validation of protein-based multiplex assays: a workshop report by the NCI-FDA interagency oncology task force on molecular diagnostics. Clin Chem. 2010 Feb; 56(2):237-43. PMID: 20007859.
    Citations: 20     Fields:    Translation:Humans
  69. Regnier FE, Skates SJ, Mesri M, Rodriguez H, Tezak Z, Kondratovich MV, Alterman MA, Levin JD, Roscoe D, Reilly E, Callaghan J, Kelm K, Brown D, Philip R, Carr SA, Liebler DC, Fisher SJ, Tempst P, Hiltke T, Kessler LG, Kinsinger CR, Ransohoff DF, Mansfield E, Anderson NL. Protein-based multiplex assays: mock presubmissions to the US Food and Drug Administration. Clin Chem. 2010 Feb; 56(2):165-71. PMID: 20007858.
    Citations: 25     Fields:    Translation:Humans
  70. Addona TA, Abbatiello SE, Schilling B, Skates SJ, Mani DR, Bunk DM, Spiegelman CH, Zimmerman LJ, Ham AJ, Keshishian H, Hall SC, Allen S, Blackman RK, Borchers CH, Buck C, Cardasis HL, Cusack MP, Dodder NG, Gibson BW, Held JM, Hiltke T, Jackson A, Johansen EB, Kinsinger CR, Li J, Mesri M, Neubert TA, Niles RK, Pulsipher TC, Ransohoff D, Rodriguez H, Rudnick PA, Smith D, Tabb DL, Tegeler TJ, Variyath AM, Vega-Montoto LJ, Wahlander A, Waldemarson S, Wang M, Whiteaker JR, Zhao L, Anderson NL, Fisher SJ, Liebler DC, Paulovich AG, Regnier FE, Tempst P, Carr SA. Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nat Biotechnol. 2009 Jul; 27(7):633-41. PMID: 19561596.
    Citations: 406     Fields:    Translation:Humans
  71. Manchanda R, Rosenthal A, Burnell M, Fraser L, Mackay J, Skates S. Change in stage distribution observed with annual screening for ovarian cancer in BRCA carriers. J Med Genet. 2009 Jun; 46(6):423-4. PMID: 19487541.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  72. Menon U, Gentry-Maharaj A, Hallett R, Ryan A, Burnell M, Sharma A, Lewis S, Davies S, Philpott S, Lopes A, Godfrey K, Oram D, Herod J, Williamson K, Seif MW, Scott I, Mould T, Woolas R, Murdoch J, Dobbs S, Amso NN, Leeson S, Cruickshank D, McGuire A, Campbell S, Fallowfield L, Singh N, Dawnay A, Skates SJ, Parmar M, Jacobs I. Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Lancet Oncol. 2009 Apr; 10(4):327-40. PMID: 19282241.
    Citations: 248     Fields:    Translation:HumansPHPublic Health
  73. Menon U, Gentry-Maharaj A, Ryan A, Sharma A, Burnell M, Hallett R, Lewis S, Lopez A, Godfrey K, Oram D, Herod J, Williamson K, Seif M, Scott I, Mould T, Woolas R, Murdoch J, Dobbs S, Amso N, Leeson S, Cruickshank D, McGuire A, Campbell S, Fallowfield L, Skates S, Parmar M, Jacobs I. Recruitment to multicentre trials--lessons from UKCTOCS: descriptive study. BMJ. 2008 Nov 13; 337:a2079. PMID: 19008269; PMCID: PMC2583394.
    Citations: 70     Fields:    Translation:HumansPHPublic Health
  74. Moore RG, McMeekin DS, Brown AK, DiSilvestro P, Miller MC, Allard WJ, Gajewski W, Kurman R, Bast RC, Skates SJ. A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass. Gynecol Oncol. 2009 Jan; 112(1):40-6. PMID: 18851871; PMCID: PMC3594094.
    Citations: 250     Fields:    Translation:HumansCTClinical Trials
  75. Drapkin R, Clauss A, Skates S. Urokinase-type plasminogen activator receptor: a beacon of malignancy? Clin Cancer Res. 2008 Sep 15; 14(18):5643-5. PMID: 18794069.
    Citations: 1     Fields:    Translation:Humans
  76. Creaney J, Yeoman D, Demelker Y, Segal A, Musk AW, Skates SJ, Robinson BW. Comparison of osteopontin, megakaryocyte potentiating factor, and mesothelin proteins as markers in the serum of patients with malignant mesothelioma. J Thorac Oncol. 2008 Aug; 3(8):851-7. PMID: 18670302.
    Citations: 36     Fields:    Translation:Humans
  77. Brown A, Miller C, Robison K, Somers E, Allard J, Granai CO, Skates S, Bast RC, Moore RG. Differential expression of CA125 and a novel serum tumor marker HE4 in epithelial ovarian cancer. J Clin Oncol. 2008 May 20; 26(15_suppl):5533. PMID: 27950487.
  78. Moore RG, Brown AK, Miller MC, Skates S, Allard WJ, Verch T, Steinhoff M, Messerlian G, DiSilvestro P, Granai CO, Bast RC. The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass. Gynecol Oncol. 2008 Feb; 108(2):402-8. PMID: 18061248.
    Citations: 219     Fields:    Translation:Humans
  79. Zhang Z, Yu Y, Xu F, Berchuck A, van Haaften-Day C, Havrilesky LJ, de Bruijn HW, van der Zee AG, Woolas RP, Jacobs IJ, Skates S, Chan DW, Bast RC. Combining multiple serum tumor markers improves detection of stage I epithelial ovarian cancer. Gynecol Oncol. 2007 Dec; 107(3):526-31. PMID: 17920110.
    Citations: 37     Fields:    Translation:Humans
  80. Lehman CD, Isaacs C, Schnall MD, Pisano ED, Ascher SM, Weatherall PT, Bluemke DA, Bowen DJ, Marcom PK, Armstrong DK, Domchek SM, Tomlinson G, Skates SJ, Gatsonis C. Cancer yield of mammography, MR, and US in high-risk women: prospective multi-institution breast cancer screening study. Radiology. 2007 Aug; 244(2):381-8. PMID: 17641362.
    Citations: 87     Fields:    Translation:HumansPHPublic Health
  81. Creaney J, van Bruggen I, Hof M, Segal A, Musk AW, de Klerk N, Horick N, Skates SJ, Robinson BW. Combined CA125 and mesothelin levels for the diagnosis of malignant mesothelioma. Chest. 2007 Oct; 132(4):1239-46. PMID: 17646232.
    Citations: 28     Fields:    Translation:Humans
  82. Yurkovetsky Z, Ta'asan S, Skates S, Rand A, Lomakin A, Linkov F, Marrangoni A, Velikokhatnaya L, Winans M, Gorelik E, Maxwell GL, Lu K, Lokshin A. Development of multimarker panel for early detection of endometrial cancer. High diagnostic power of prolactin. Gynecol Oncol. 2007 Oct; 107(1):58-65. PMID: 17659325; PMCID: PMC2777971.
    Citations: 35     Fields:    Translation:Humans
  83. Creaney J, Yeoman D, Naumoff LK, Hof M, Segal A, Musk AW, De Klerk N, Horick N, Skates SJ, Robinson BW. Soluble mesothelin in effusions: a useful tool for the diagnosis of malignant mesothelioma. Thorax. 2007 Jul; 62(7):569-76. PMID: 17356060; PMCID: PMC2117248.
    Citations: 35     Fields:    Translation:Humans
  84. Skates SJ, Horick NK, Moy JM, Minihan AM, Seiden MV, Marks JR, Sluss P, Cramer DW. Pooling of case specimens to create standard serum sets for screening cancer biomarkers. Cancer Epidemiol Biomarkers Prev. 2007 Feb; 16(2):334-41. PMID: 17301268.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  85. Bast RC, Brewer M, Zou C, Hernandez MA, Daley M, Ozols R, Lu K, Lu Z, Badgwell D, Mills GB, Skates S, Zhang Z, Chan D, Lokshin A, Yu Y. Prevention and early detection of ovarian cancer: mission impossible? Recent Results Cancer Res. 2007; 174:91-100. PMID: 17302189.
    Citations: 35     Fields:    Translation:HumansAnimalsPHPublic Health
  86. Jacobs IJ, Mackay J, Menon U, Skates SJ, Rosenthal AN, Fraser L. Familial ovarian screening--effective or ineffective? Br J Cancer. 2006 Oct 23; 95(8):1124; author reply 1126-7. PMID: 17047658; PMCID: PMC2360716.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  87. Ye B, Skates S, Mok SC, Horick NK, Rosenberg HF, Vitonis A, Edwards D, Sluss P, Han WK, Berkowitz RS, Cramer DW. Proteomic-based discovery and characterization of glycosylated eosinophil-derived neurotoxin and COOH-terminal osteopontin fragments for ovarian cancer in urine. Clin Cancer Res. 2006 Jan 15; 12(2):432-41. PMID: 16428483.
    Citations: 46     Fields:    Translation:HumansCells
  88. Baker SG, Kramer BS, McIntosh M, Patterson BH, Shyr Y, Skates S. Evaluating markers for the early detection of cancer: overview of study designs and methods. Clin Trials. 2006; 3(1):43-56. PMID: 16539089.
    Citations: 30     Fields:    Translation:Humans
  89. Bast RC, Badgwell D, Lu Z, Marquez R, Rosen D, Liu J, Baggerly KA, Atkinson EN, Skates S, Zhang Z, Lokshin A, Menon U, Jacobs I, Lu K. New tumor markers: CA125 and beyond. Int J Gynecol Cancer. 2005 Nov-Dec; 15 Suppl 3:274-81. PMID: 16343244.
    Citations: 156     Fields:    Translation:Humans
  90. Menon U, Skates SJ, Lewis S, Rosenthal AN, Rufford B, Sibley K, Macdonald N, Dawnay A, Jeyarajah A, Bast RC, Oram D, Jacobs IJ. Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer. J Clin Oncol. 2005 Nov 01; 23(31):7919-26. PMID: 16258091.
    Citations: 58     Fields:    Translation:HumansPHPublic Health
  91. Skates SJ, Horick N, Yu Y, Xu FJ, Berchuck A, Havrilesky LJ, de Bruijn HW, van der Zee AG, Woolas RP, Jacobs IJ, Zhang Z, Bast RC. Preoperative sensitivity and specificity for early-stage ovarian cancer when combining cancer antigen CA-125II, CA 15-3, CA 72-4, and macrophage colony-stimulating factor using mixtures of multivariate normal distributions. J Clin Oncol. 2004 Oct 15; 22(20):4059-66. PMID: 15381683.
    Citations: 50     Fields:    Translation:Humans
  92. Skates S, Iliopoulos O. Molecular markers for early detection of renal carcinoma: investigative approach. Clin Cancer Res. 2004 Sep 15; 10(18 Pt 2):6296S-301S. PMID: 15448020.
    Citations: 3     Fields:    Translation:Humans
  93. Isaacs C, Skates SJ, Lehman C, Marcom K, Bowen DJ, Domchek S, Tomlinson G, Armstrong DK, Schnall M. Mammographic, MRI, and ultrasound characteristics of BRCA1, BRCA2, and other genetically high-risk women enrolled in a prospective multi-institution breast cancer screening trial. J Clin Oncol. 2004 Jul 15; 22(14_suppl):9588. PMID: 28016731.
  94. Schorge JO, Drake RD, Lee H, Skates SJ, Rajanbabu R, Miller DS, Kim JH, Cramer DW, Berkowitz RS, Mok SC. Osteopontin as an adjunct to CA125 in detecting recurrent ovarian cancer. Clin Cancer Res. 2004 May 15; 10(10):3474-8. PMID: 15161704.
    Citations: 28     Fields:    Translation:HumansCells
  95. Penson RT, Oliva E, Skates SJ, Glyptis T, Fuller AF, Goodman A, Seiden MV. Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples. Gynecol Oncol. 2004 Apr; 93(1):98-106. PMID: 15047220.
    Citations: 58     Fields:    Translation:Humans
  96. Terry KL, Sluss PM, Skates SJ, Mok SC, Ye B, Vitonis AF, Cramer DW. Blood and urine markers for ovarian cancer: a comprehensive review. Dis Markers. 2004; 20(2):53-70. PMID: 15322314; PMCID: PMC3839278.
    Citations: 20     Fields:    Translation:Humans
  97. Kim JH, Herlyn D, Wong KK, Park DC, Schorge JO, Lu KH, Skates SJ, Cramer DW, Berkowitz RS, Mok SC. Identification of epithelial cell adhesion molecule autoantibody in patients with ovarian cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4782-91. PMID: 14581349.
    Citations: 28     Fields:    Translation:HumansCells
  98. Skates S, Troiano R, Knapp RC. Longitudinal CA125 detection of sporadic papillary serous carcinoma of the peritoneum. Int J Gynecol Cancer. 2003 Sep-Oct; 13(5):693-6. PMID: 14675358.
    Citations: 7     Fields:    Translation:Humans
  99. Ye B, Cramer DW, Skates SJ, Gygi SP, Pratomo V, Fu L, Horick NK, Licklider LJ, Schorge JO, Berkowitz RS, Mok SC. Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: identification and characterization using proteomic profiling and mass spectrometry. Clin Cancer Res. 2003 Aug 01; 9(8):2904-11. PMID: 12912935.
    Citations: 64     Fields:    Translation:HumansCells
  100. Cannistra SA, Bast RC, Berek JS, Bookman MA, Crum CP, DePriest PD, Garber JE, Koh WJ, Markman M, McGuire WP, Rose PG, Rowinsky EK, Rustin GJ, Skates SJ, Vasey PA, King L. Progress in the management of gynecologic cancer: consensus summary statement. J Clin Oncol. 2003 May 15; 21(10 Suppl):129s-132s. PMID: 12743127.
    Citations: 13     Fields:    Translation:HumansPHPublic Health
  101. Skates SJ, Menon U, MacDonald N, Rosenthal AN, Oram DH, Knapp RC, Jacobs IJ. Calculation of the risk of ovarian cancer from serial CA-125 values for preclinical detection in postmenopausal women. J Clin Oncol. 2003 May 15; 21(10 Suppl):206s-210s. PMID: 12743136.
    Citations: 60     Fields:    Translation:HumansPHPublic Health
  102. Kim JH, Skates SJ, Uede T, Wong KK, Schorge JO, Feltmate CM, Berkowitz RS, Cramer DW, Mok SC. Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA. 2002 Apr 03; 287(13):1671-9. PMID: 11926891.
    Citations: 109     Fields:    Translation:HumansCells
  103. Skates SJ. Screening for ovarian cancer-risk, education, worry: path to appropriate use? Gynecol Oncol. 2002 Apr; 85(1):1-2. PMID: 11925112.
    Citations:    Fields:    Translation:HumansPHPublic Health
  104. Parmigiani G, Skates S, Zelen M. Modeling and optimization in early detection programs with a single exam. Biometrics. 2002 Mar; 58(1):30-6. PMID: 11890325.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  105. Bast RC, Urban N, Shridhar V, Smith D, Zhang Z, Skates S, Lu K, Liu J, Fishman D, Mills G. Early detection of ovarian cancer: promise and reality. Cancer Treat Res. 2002; 107:61-97. PMID: 11775462.
    Citations: 40     Fields:    Translation:HumansPHPublic Health
  106. Mok SC, Chao J, Skates S, Wong K, Yiu GK, Muto MG, Berkowitz RS, Cramer DW. Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology. J Natl Cancer Inst. 2001 Oct 03; 93(19):1458-64. PMID: 11584061.
    Citations: 66     Fields:    Translation:HumansCellsPHPublic Health
  107. Zweemer RP, Verheijen RH, Coebergh JW, Jacobs IJ, van Diest PJ, Gille JJ, Skates S, Menko FH, Ten Kate LP, Kenemans P. Survival analysis in familial ovarian cancer, a case control study. Eur J Obstet Gynecol Reprod Biol. 2001 Oct; 98(2):219-23. PMID: 11574135.
    Citations: 11     Fields:    Translation:Humans
  108. Hylek EM, Regan S, Go AS, Hughes RA, Singer DE, Skates SJ. Clinical predictors of prolonged delay in return of the international normalized ratio to within the therapeutic range after excessive anticoagulation with warfarin. Ann Intern Med. 2001 Sep 18; 135(6):393-400. PMID: 11560452.
    Citations: 26     Fields:    Translation:Humans
  109. Pauler DK, Menon U, McIntosh M, Symecko HL, Skates SJ, Jacobs IJ. Factors influencing serum CA125II levels in healthy postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2001 May; 10(5):489-93. PMID: 11352859.
    Citations: 48     Fields:    Translation:HumansPHPublic Health
  110. Skates SJ, Jacobs IJ, Knapp RC. Tumor markers in screening for ovarian cancer. Methods Mol Med. 2001; 39:61-73. PMID: 21340758.
    Citations: 3     Fields:    
  111. Hylek EM, Chang YC, Skates SJ, Hughes RA, Singer DE. Prospective study of the outcomes of ambulatory patients with excessive warfarin anticoagulation. Arch Intern Med. 2000 Jun 12; 160(11):1612-7. PMID: 10847254.
    Citations: 36     Fields:    Translation:Humans
  112. Menon U, Talaat A, Rosenthal AN, Macdonald ND, Jeyerajah AR, Skates SJ, Sibley K, Oram DH, Jacobs IJ. Performance of ultrasound as a second line test to serum CA125 in ovarian cancer screening. BJOG. 2000 Feb; 107(2):165-9. PMID: 10688498.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  113. Jacobs I, Skates S, Macdonald N. Ovarian cancer screening was feasible but did not decrease incidence of index cancer or mortality. West J Med. 2000 Feb; 172(2):97. PMID: 18751238.
    Citations:    Fields:    
  114. Penson RT, Skates SJ, Fuller AJ, Seiden MV. Clinical course of stage IV epithelial ovarian cancer. J Clin Oncol. 1999 Oct; 17(10):3361-2. PMID: 10506641.
    Citations: 2     Fields:    Translation:Humans
  115. Menon U, Talaat A, Jeyarajah AR, Rosenthal AN, MacDonald ND, Skates SJ, Sibley K, Oram DH, Jacobs IJ. Ultrasound assessment of ovarian cancer risk in postmenopausal women with CA125 elevation. Br J Cancer. 1999 Jul; 80(10):1644-7. PMID: 10408412; PMCID: PMC2363093.
    Citations: 7     Fields:    Translation:Humans
  116. Jeyarajah AR, Ind TE, MacDonald N, Skates S, Oram DH, Jacobs IJ. Increased mortality in postmenopausal women with serum CA125 elevation. Gynecol Oncol. 1999 May; 73(2):242-6. PMID: 10329041.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  117. Jeyarajah AR, Ind TE, Skates S, Oram DH, Jacobs IJ. Serum CA125 elevation and risk of clinical detection of cancer in asymptomatic postmenopausal women. Cancer. 1999 May 01; 85(9):2068-72. PMID: 10223249.
    Citations: 5     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  118. Jacobs IJ, Skates SJ, MacDonald N, Menon U, Rosenthal AN, Davies AP, Woolas R, Jeyarajah AR, Sibley K, Lowe DG, Oram DH. Screening for ovarian cancer: a pilot randomised controlled trial. Lancet. 1999 Apr 10; 353(9160):1207-10. PMID: 10217079.
    Citations: 88     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  119. Eliason BC, Larson W, Singer DE, Skates SJ. Acetaminophen and risk factors for excess anticoagulation with warfarin. JAMA. 1998 Aug 26; 280(8):696-7. PMID: 9728633.
    Citations:    Fields:    Translation:Humans
  120. Lein M, Koenig F, Jung K, McGovern FJ, Skates SJ, Schnorr D, Loening SA. The percentage of free prostate specific antigen is an age-independent tumour marker for prostate cancer: establishment of reference ranges in a large population of healthy men. Br J Urol. 1998 Aug; 82(2):231-6. PMID: 9722758.
    Citations: 5     Fields:    Translation:Humans
  121. Hylek EM, Heiman H, Skates SJ, Sheehan MA, Singer DE. Acetaminophen and other risk factors for excessive warfarin anticoagulation. JAMA. 1998 Mar 04; 279(9):657-62. PMID: 9496982.
    Citations: 54     Fields:    Translation:Humans
  122. Merkel PA, Polisson RP, Chang Y, Skates SJ, Niles JL. Prevalence of antineutrophil cytoplasmic antibodies in a large inception cohort of patients with connective tissue disease. Ann Intern Med. 1997 Jun 01; 126(11):866-73. PMID: 9163287.
    Citations: 40     Fields:    Translation:HumansCTClinical Trials
  123. Jacobs IJ, Skates S, Davies AP, Woolas RP, Jeyerajah A, Weidemann P, Sibley K, Oram DH. Risk of diagnosis of ovarian cancer after raised serum CA 125 concentration: a prospective cohort study. BMJ. 1996 Nov 30; 313(7069):1355-8. PMID: 8956699; PMCID: PMC2352927.
    Citations: 34     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  124. Hylek EM, Skates SJ, Sheehan MA, Singer DE. An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation. N Engl J Med. 1996 Aug 22; 335(8):540-6. PMID: 8678931.
    Citations: 147     Fields:    Translation:Humans
  125. Skates SJ, Xu FJ, Yu YH, Sjövall K, Einhorn N, Chang Y, Bast RC, Knapp RC. Toward an optimal algorithm for ovarian cancer screening with longitudinal tumor markers. Cancer. 1995 Nov 15; 76(10 Suppl):2004-10. PMID: 8634992.
    Citations: 52     Fields:    Translation:HumansPHPublic Health
  126. Carlson KJ, Skates SJ, Singer DE. Screening for ovarian cancer. Ann Intern Med. 1994 Jul 15; 121(2):124-32. PMID: 8017726.
    Citations: 24     Fields:    Translation:HumansPHPublic Health
  127. Atlas SJ, Singer DE, Skates SJ. Changing blood use in the AIDS era: the case of elective hip surgery. Transfusion. 1994 May; 34(5):386-91. PMID: 8191561.
    Citations:    Fields:    Translation:Humans
  128. Maciejewski BA, Skates S, Zajusz A, Lange D. Importance of tumor size and repopulation for radiocurability of skin cancer. Neoplasma. 1993; 40(1):51-4. PMID: 8350948.
    Citations: 3     Fields:    Translation:Humans
  129. Suit H, Skates S, Taghian A, Okunieff P, Efird JT. Clinical implications of heterogeneity of tumor response to radiation therapy. Radiother Oncol. 1992 Dec; 25(4):251-60. PMID: 1480770.
    Citations: 19     Fields:    Translation:Humans
  130. Urie MM, Fullerton B, Tatsuzaki H, Birnbaum S, Suit HD, Convery K, Skates S, Goitein M. A dose response analysis of injury to cranial nerves and/or nuclei following proton beam radiation therapy. Int J Radiat Oncol Biol Phys. 1992; 23(1):27-39. PMID: 1572828.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  131. Eagle KA, Mulley AG, Field TS, Skates S, Bero G, Clark CE, Sexton JO, Reder VA, Berrigan G, Procaccini J, et al. Variation in intensive care unit practices in two community hospitals. Med Care. 1991 Dec; 29(12):1237-45. PMID: 1745081.
    Citations: 1     Fields:    Translation:Humans
  132. Niles JL, Pan GL, Collins AB, Shannon T, Skates S, Fienberg R, Arnaout MA, McCluskey RT. Antigen-specific radioimmunoassays for anti-neutrophil cytoplasmic antibodies in the diagnosis of rapidly progressive glomerulonephritis. J Am Soc Nephrol. 1991 Jul; 2(1):27-36. PMID: 1655091.
    Citations: 10     Fields:    Translation:HumansCells
  133. Rigotti NA, Neer RM, Skates SJ, Herzog DB, Nussbaum SR. The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass. JAMA. 1991 Mar 06; 265(9):1133-8. PMID: 1995999.
    Citations: 83     Fields:    Translation:Humans
  134. Skates SJ, Singer DE. Quantifying the potential benefit of CA 125 screening for ovarian cancer. J Clin Epidemiol. 1991; 44(4-5):365-80. PMID: 2010780.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  135. Eagle KA, Mulley AG, Skates SJ, Reder VA, Nicholson BW, Sexton JO, Barnett GO, Thibault GE. Length of stay in the intensive care unit. Effects of practice guidelines and feedback. JAMA. 1990 Aug 22-29; 264(8):992-7. PMID: 2376892.
    Citations: 10     Fields:    Translation:Humans
  136. Thor AD, Schwartz LH, Koerner FC, Edgerton SM, Skates SJ, Yin S, McKenzie SJ, Panicali DL, Marks PJ, Fingert HJ, et al. Analysis of c-erbB-2 expression in breast carcinomas with clinical follow-up. Cancer Res. 1989 Dec 15; 49(24 Pt 1):7147-52. PMID: 2573426.
    Citations: 24     Fields:    Translation:Humans
  137. Suit HD, Baumann M, Skates S, Convery K. Clinical interest in determinations of cellular radiation sensitivity. Int J Radiat Biol. 1989 Nov; 56(5):725-37. PMID: 2573670.
    Citations: 5     Fields:    Translation:HumansCells
  138. Tolentino FI, Cajita VN, Gancayco T, Skates S. Vitreous hemorrhage after closed vitrectomy for proliferative diabetic retinopathy. Ophthalmology. 1989 Oct; 96(10):1495-500. PMID: 2587044.
    Citations: 21     Fields:    Translation:Humans
  139. Lauk S, Skates S, Goodman M, Suit HD. A morphometric study of the vascularity of oral squamous cell carcinomas and its relation to outcome of radiation therapy. Eur J Cancer Clin Oncol. 1989 Oct; 25(10):1431-40. PMID: 2591435.
    Citations: 5     Fields:    Translation:Humans
  140. Lauk S, Zietman A, Skates S, Fabian R, Suit HD. Comparative morphometric study of tumor vasculature in human squamous cell carcinomas and their xenotransplants in athymic nude mice. Cancer Res. 1989 Aug 15; 49(16):4557-61. PMID: 2743340.
    Citations: 14     Fields:    Translation:HumansAnimals
  141. Austin-Seymour M, Munzenrider J, Goitein M, Verhey L, Urie M, Gentry R, Birnbaum S, Ruotolo D, McManus P, Skates S, et al. Fractionated proton radiation therapy of chordoma and low-grade chondrosarcoma of the base of the skull. J Neurosurg. 1989 Jan; 70(1):13-7. PMID: 2535872.
    Citations: 37     Fields:    Translation:HumansPHPublic Health
  142. Okunieff P, Rummeny E, Vaupel P, Skates S, Willett C, Neuringer LJ, Suit HD. Effects of pentobarbital anesthesia on the energy metabolism of murine tumors studied by in vivo 31P nuclear magnetic resonance spectroscopy. Radiat Res. 1988 Aug; 115(2):361-72. PMID: 3406373.
    Citations: 1     Fields:    Translation:Animals
  143. Willett CG, Stracher MA, Linggood RM, Miketic LM, Leong JC, Skates SJ, Kushner DC, Jacobson JO. Three-dimensional volumetric assessment of response to treatment: stage I and II diffuse large cell lymphoma of the mediastinum. Radiother Oncol. 1988 Jul; 12(3):193-8. PMID: 3175046.
    Citations:    Fields:    Translation:Humans
  144. Willett CG, Linggood RM, Leong JC, Miketic LM, Stracher MA, Skates SJ, Kushner DC. Stage IA to IIB mediastinal Hodgkin's disease: three-dimensional volumetric assessment of response to treatment. J Clin Oncol. 1988 May; 6(5):819-24. PMID: 3367187.
    Citations: 1     Fields:    Translation:Humans
  145. Willett CG, Tepper JE, Skates SJ, Wood WC, Orlow EC, Duttenhaver JR. Adjuvant postoperative radiation therapy for colonic carcinoma. Ann Surg. 1987 Dec; 206(6):694-8. PMID: 3689006; PMCID: PMC1493317.
    Citations: 4     Fields:    Translation:Humans
  146. Keast D, Rowe P, Sanfelieu L, Shannahan J, Bowra B, Skates S, Stapley EO, Woodruff HB. Use of a computer to group actinomycetes for studies on the ecology of soil microorganisms. Appl Environ Microbiol. 1984 Oct; 48(4):791-6. PMID: 6508288.
    Citations:    Fields:    Translation:CellsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.