Harvard Catalyst Profiles

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Lee Josephson, Ph.D.

Co-Author

This page shows the publications co-authored by Lee Josephson and Steven Liang.
Connection Strength

4.787
  1. Preliminary evaluation of [11C]MAGL-0519 as a promising PET ligand for the diagnosis of Hepatocellular carcinoma. Bioorg Chem. 2022 Jan 12; 120:105620.
    View in: PubMed
    Score: 0.245
  2. The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO. J Med Chem. 2021 12 23; 64(24):17656-17689.
    View in: PubMed
    Score: 0.244
  3. Imaging Autotaxin In Vivo with 18F-Labeled Positron Emission Tomography Ligands. J Med Chem. 2021 10 28; 64(20):15053-15068.
    View in: PubMed
    Score: 0.241
  4. [18F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models. Acta Pharm Sin B. 2022 Jan; 12(1):308-315.
    View in: PubMed
    Score: 0.237
  5. Advances in Cyclic Nucleotide Phosphodiesterase-Targeted PET Imaging and Drug Discovery. J Med Chem. 2021 06 10; 64(11):7083-7109.
    View in: PubMed
    Score: 0.235
  6. Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping. Acta Pharm Sin B. 2021 Jun; 11(6):1686-1695.
    View in: PubMed
    Score: 0.232
  7. Recent developments on PET radiotracers for TSPO and their applications in neuroimaging. Acta Pharm Sin B. 2021 Feb; 11(2):373-393.
    View in: PubMed
    Score: 0.223
  8. Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators. Acta Pharmacol Sin. 2021 Mar; 42(3):491-498.
    View in: PubMed
    Score: 0.221
  9. Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging. Bioorg Med Chem Lett. 2020 08 15; 30(16):127326.
    View in: PubMed
    Score: 0.220
  10. Synthesis and pharmacokinetic study of a 11C-labeled cholesterol 24-hydroxylase inhibitor using 'in-loop' [11C]CO2 fixation method. Bioorg Med Chem Lett. 2020 05 01; 30(9):127068.
    View in: PubMed
    Score: 0.216
  11. [18F]-Alfatide PET imaging of integrin avß3 for the non-invasive quantification of liver fibrosis. J Hepatol. 2020 07; 73(1):161-169.
    View in: PubMed
    Score: 0.216
  12. Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging ?-8 dependent transmembrane AMPA receptor regulatory protein by PET. Bioorg Med Chem Lett. 2020 02 15; 30(4):126879.
    View in: PubMed
    Score: 0.212
  13. Design, Synthesis, and Evaluation of 18F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes. J Med Chem. 2019 10 10; 62(19):8866-8872.
    View in: PubMed
    Score: 0.209
  14. Synthesis and Preliminary Evaluation of [11 C]GNE-1023 as a Potent PET Probe for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease. ChemMedChem. 2019 09 04; 14(17):1580-1585.
    View in: PubMed
    Score: 0.208
  15. Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton. J Med Chem. 2019 04 11; 62(7):3336-3353.
    View in: PubMed
    Score: 0.202
  16. Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain. ACS Chem Neurosci. 2019 05 15; 10(5):2263-2275.
    View in: PubMed
    Score: 0.201
  17. Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions. Angew Chem Int Ed Engl. 2019 02 25; 58(9):2580-2605.
    View in: PubMed
    Score: 0.199
  18. PET/SPECT Molecular Probes for the Diagnosis and Staging of Nonalcoholic Fatty Liver Disease. Mol Imaging. 2019 Jan-Dec; 18:1536012119871455.
    View in: PubMed
    Score: 0.199
  19. Synthesis and Preliminary Evaluation of 11 C-Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype 4. ChemMedChem. 2019 02 05; 14(3):303-309.
    View in: PubMed
    Score: 0.199
  20. Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-Methyl-d-aspartate (NMDA), a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors. J Med Chem. 2019 01 24; 62(2):403-419.
    View in: PubMed
    Score: 0.194
  21. Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging ?8-dependent transmembrane AMPA receptor regulatory protein. Eur J Med Chem. 2018 Sep 05; 157:898-908.
    View in: PubMed
    Score: 0.193
  22. The Binding of BF-227-Like Benzoxazoles to Human a-Synuclein and Amyloid ß Peptide Fibrils. Mol Imaging. 2018 Jan-Dec; 17:1536012118796297.
    View in: PubMed
    Score: 0.185
  23. In Vitro Evaluation of [3H]CPPC as a Tool Radioligand for CSF-1R. ACS Chem Neurosci. 2021 03 17; 12(6):998-1006.
    View in: PubMed
    Score: 0.058
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.