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profileMarlene P Freeman, M.D.

TitleAssociate Professor of Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
Psychiatry, Simches 2
185 Cambridge St
Boston MA 02114
Phone617/732-6750
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R21MH096006     (COHEN, LEE S)Aug 1, 2012 - Jul 31, 2014
NIH/NIMH
Course and predictors of depressive relapse during IVF
Role: Co-Principal Investigator

K23MH066265     (FREEMAN, MARLENE P)Sep 1, 2002 - Jun 30, 2007
NIH/NIMH
Postpartum Depression: Omega-3 FA vs Placebo
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Freeman MP, Cheng LJ, Moustafa D, Davies A, Sosinsky AZ, Wang B, Petrillo LF, Hogan C, Cohen LS. Vortioxetine for major depressive disorder, vasomotor, and cognitive symptoms associated with the menopausal transition. Ann Clin Psychiatry. 2017 Nov; 29(4):249-257. PMID: 29069110.
    View in: PubMed
  2. Peters W, Freeman MP, Kim S, Cohen LS, Joffe H. Treatment of Premenstrual Breakthrough of Depression With Adjunctive Oral Contraceptive Pills Compared With Placebo. J Clin Psychopharmacol. 2017 Oct; 37(5):609-614. PMID: 28816924.
    View in: PubMed
  3. Fava M, Freeman MP, Flynn M, Hoeppner BB, Shelton R, Iosifescu DV, Murrough JW, Mischoulon D, Cusin C, Rapaport M, Dunlop BW, Trivedi MH, Jha M, Sanacora G, Hermes G, Papakostas GI. Double-blind, proof-of-concept (POC) trial of Low-Field Magnetic Stimulation (LFMS) augmentation of antidepressant therapy in treatment-resistant depression (TRD). Brain Stimul. 2017 Sep 23. PMID: 29030111.
    View in: PubMed
  4. Freeman MP, Sosinsky AZ, Goez-Mogollon L, Savella GM, Moustafa D, Viguera AC, Cohen LS. Gestational Weight Gain and Pre-pregnancy Body Mass Index Associated With Second-Generation Antipsychotic Drug Use During Pregnancy. Psychosomatics. 2017 Sep 21. PMID: 29078988.
    View in: PubMed
  5. Sosinsky AZ, Freeman MP, Savella GM, Cheng LJ, Viguera AC, Cohen LS. Delusional Pregnancy Presenting to the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. J Clin Psychopharmacol. 2017 Aug; 37(4):472-474. PMID: 28614160.
    View in: PubMed
  6. Panchaud A, Hernandez-Diaz S, Freeman MP, Viguera AC, MacDonald SC, Sosinsky AZ, Cohen LS. Use of atypical antipsychotics in pregnancy and maternal gestational diabetes. J Psychiatr Res. 2017 Dec; 95:84-90. PMID: 28810177.
    View in: PubMed
  7. Freeman MP. Introduction. J Clin Psychiatry. 2017 May; 78(5):604. PMID: 28570795.
    View in: PubMed
  8. Freeman MP, Pooley J, Flynn MJ, Baer L, Mischoulon D, Mou D, Fava M. Guarding the Gate: Remote Structured Assessments to Enhance Enrollment Precision in Depression Trials. J Clin Psychopharmacol. 2017 Apr; 37(2):176-181. PMID: 28187008.
    View in: PubMed
  9. Freeman MP, Fisher L, Clain A, Rabbitt R, Pooley J, Baer L, Fava M. Differentiating residual symptoms of depression from adverse events among patients initiating treatment with an antidepressant. Ann Clin Psychiatry. 2017 Feb; 29(1):28-34. PMID: 28207913.
    View in: PubMed
  10. Gelenberg AJ, Freeman MP. Thank You to Our Peer Reviewers. J Clin Psychiatry. 2017 Jan; 78(1):87-89. PMID: 28129496.
    View in: PubMed
  11. Freeman MP. Introduction. J Clin Psychiatry. 2016 Nov; 77(11):1526. PMID: 28076670.
    View in: PubMed
  12. Joffe H, Crawford SL, Freeman MP, White DP, Bianchi MT, Kim S, Economou N, Camuso J, Hall JE, Cohen LS. Independent Contributions of Nocturnal Hot Flashes and Sleep Disturbance to Depression in Estrogen-Deprived Women. J Clin Endocrinol Metab. 2016 Oct; 101(10):3847-3855. PMID: 27680875.
    View in: PubMed
  13. Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freeman MP. A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients. Mol Psychiatry. 2016 Oct; 21(10):1483-4. PMID: 27528461.
    View in: PubMed
  14. Mischoulon D, Zajecka J, Freeman MP, Fava M. Does folic acid interfere with lamotrigine? Lancet Psychiatry. 2016 Aug; 3(8):704-5. PMID: 27475760.
    View in: PubMed
  15. Hogan CS, Freeman MP. Adverse Effects in the Pharmacologic Management of Bipolar Disorder During Pregnancy. Psychiatr Clin North Am. 2016 09; 39(3):465-75. PMID: 27514299.
    View in: PubMed
  16. Venkatesh KK, Nadel H, Blewett D, Freeman MP, Kaimal AJ, Riley LE. Implementation of universal screening for depression during pregnancy: feasibility and impact on obstetric care. Am J Obstet Gynecol. 2016 Oct; 215(4):517.e1-8. PMID: 27210067.
    View in: PubMed
  17. Freeman MP. Wishful thinking is not effective contraception: family planning, contraception, and safe prescribing. J Clin Psychiatry. 2016 Apr; 77(4):523-4. PMID: 27137419.
    View in: PubMed
  18. Freeman MP, Fava M, Gommoll C, Chen C, Greenberg WM, Ruth A. Effects of levomilnacipran ER on fatigue symptoms associated with major depressive disorder. Int Clin Psychopharmacol. 2016 Mar; 31(2):100-9. PMID: 26584326; PMCID: PMC4736297.
  19. Meyer F, Freeman MP, Petrillo L, Barsky M, Galvan T, Kim S, Cohen L, Joffe H. Armodafinil for fatigue associated with menopause: an open-label trial. Menopause. 2016 Feb; 23(2):209-14. PMID: 26125538.
    View in: PubMed
  20. Gelenberg AJ, Freeman MP. New year's greetings and gratitude. J Clin Psychiatry. 2016 Jan; 77(1):48. PMID: 26845262.
    View in: PubMed
  21. Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freeman MP. A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients. Mol Psychiatry. 2016 Oct; 21(10):1372-80. PMID: 26643541.
    View in: PubMed
  22. Freeman MP, Sosinsky AZ, Moustafa D, Viguera AC, Cohen LS. Supplement use by women during pregnancy: data from the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. Arch Womens Ment Health. 2016 Jun; 19(3):437-41. PMID: 26472040.
    View in: PubMed
  23. Cohen LS, Viguera AC, McInerney KA, Freeman MP, Sosinsky AZ, Moustafa D, Marfurt SP, Kwiatkowski MA, Murphy SK, Farrell AM, Chitayat D, Hernández-Díaz S. Reproductive Safety of Second-Generation Antipsychotics: Current Data From the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. Am J Psychiatry. 2016 Mar 01; 173(3):263-70. PMID: 26441156.
    View in: PubMed
  24. Sarris J, Logan AC, Akbaraly TN, Paul Amminger G, Balanzá-Martínez V, Freeman MP, Hibbeln J, Matsuoka Y, Mischoulon D, Mizoue T, Nanri A, Nishi D, Parletta N, Ramsey D, Rucklidge JJ, Sanchez-Villegas A, Scholey A, Su KP, Jacka FN. International Society for Nutritional Psychiatry Research consensus position statement: nutritional medicine in modern psychiatry. World Psychiatry. 2015 Oct; 14(3):370-1. PMID: 26407799; PMCID: PMC4592666.
  25. Fisher LB, Fava M, Doros GD, Alpert JE, Henry M, Huz I, Freeman MP. The Role of Anger/Hostility in Treatment-Resistant Depression: A Secondary Analysis From the ADAPT-A Study. J Nerv Ment Dis. 2015 Oct; 203(10):762-8. PMID: 26348584.
    View in: PubMed
  26. Freeman MP, McInerney K, Sosinsky AZ, Kwiatkowski MA, Cohen LS. Omega-3 fatty acids for atypical antipsychotic-associated hypertriglyceridemia. Ann Clin Psychiatry. 2015 Aug; 27(3):197-202. PMID: 26247219.
    View in: PubMed
  27. Freeman MP. Focus on Women’s Mental Health. Introduction. J Clin Psychiatry. 2015 Jul; 76(7):965-6. PMID: 26231007.
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  28. Freeman MP. Psychotropic medication use during pregnancy: changes to the labeling system and the importance of exposure registries. J Clin Psychiatry. 2015 Jul; 76(7):990-1. PMID: 26231008.
    View in: PubMed
  29. Goldberg JF, Freeman MP, Balon R, Citrome L, Thase ME, Kane JM, Fava M. THE AMERICAN SOCIETY OF CLINICAL PSYCHOPHARMACOLOGY SURVEY OF PSYCHOPHARMACOLOGISTS' PRACTICE PATTERNS FOR THE TREATMENT OF MOOD DISORDERS. Depress Anxiety. 2015 Aug; 32(8):605-13. PMID: 26129956.
    View in: PubMed
  30. Sarris J, Logan AC, Akbaraly TN, Amminger GP, Balanzá-Martínez V, Freeman MP, Hibbeln J, Matsuoka Y, Mischoulon D, Mizoue T, Nanri A, Nishi D, Ramsey D, Rucklidge JJ, Sanchez-Villegas A, Scholey A, Su KP, Jacka FN. Nutritional medicine as mainstream in psychiatry. Lancet Psychiatry. 2015 Mar; 2(3):271-4. PMID: 26359904.
    View in: PubMed
  31. Goodman JH, Prager J, Goldstein R, Freeman M. Perinatal Dyadic Psychotherapy for postpartum depression: a randomized controlled pilot trial. Arch Womens Ment Health. 2015 Jun; 18(3):493-506. PMID: 25522664; PMCID: PMC4439372.
  32. Freeman MP, Cohen LS, McInerney K. Omega-3 Fatty acids and gestational length in a high-risk psychiatric population due to psychiatric morbidity and medication exposure during pregnancy. J Clin Psychopharmacol. 2014 Oct; 34(5):627-32. PMID: 25006815.
    View in: PubMed
  33. Freeman MP. Perinatal psychiatry: an emerging specialty. J Clin Psychiatry. 2014 Oct; 75(10):1086-7. PMID: 25373116.
    View in: PubMed
  34. Goodman JH, Chenausky KL, Freeman MP. Anxiety disorders during pregnancy: a systematic review. J Clin Psychiatry. 2014 Oct; 75(10):e1153-84. PMID: 25373126.
    View in: PubMed
  35. Psaros C, Freeman M, Safren SA, Barsky M, Cohen LS. Discontinuation of antidepressants during attempts to conceive: a pilot trial of cognitive behavioral therapy for the prevention of recurrent depression. J Clin Psychopharmacol. 2014 Aug; 34(4):455-60. PMID: 24911438; PMCID: PMC4959421.
  36. Shivakumar G, Brandon AR, Johnson NL, Freeman MP. Screening to Treatment: Obstacles and Predictors in Perinatal Depression (STOP-PPD) in the Dallas Healthy Start program. Arch Womens Ment Health. 2014 Dec; 17(6):575-8. PMID: 25012198.
    View in: PubMed
  37. Freeman MP. ADHD and pregnancy. Am J Psychiatry. 2014 Jul; 171(7):723-8. PMID: 24980168.
    View in: PubMed
  38. Byatt N, Freeman MP. Exposure to selective serotonin reuptake inhibitors in late pregnancy increases the risk of persistent pulmonary hypertension of the newborn, but the absolute risk is low. Evid Based Nurs. 2015 Jan; 18(1):15-6. PMID: 24858440; PMCID: PMC4241385.
  39. Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, Carpenter JS, Learman LA, Newton KM, Reed SD, Manson JE, Sternfeld B, Caan B, Freeman EW, LaCroix AZ, Tinker LF, Booth-Laforce C, Larson JC, Anderson GL. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014 Apr; 21(4):347-54. PMID: 23982113; PMCID: PMC4072122.
  40. Freeman MP. The changing landscape of psychiatry. J Clin Psychiatry. 2014 Apr; 75(4):377-8. PMID: 24813405.
    View in: PubMed
  41. Deligiannidis KM, Byatt N, Freeman MP. Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. J Clin Psychopharmacol. 2014 Apr; 34(2):244-55. PMID: 24525634; PMCID: PMC4105343.
  42. Goodman JH, Guarino A, Chenausky K, Klein L, Prager J, Petersen R, Forget A, Freeman M. CALM Pregnancy: results of a pilot study of mindfulness-based cognitive therapy for perinatal anxiety. Arch Womens Ment Health. 2014 Oct; 17(5):373-87. PMID: 24449191; PMCID: PMC4107206.
  43. Gelenberg AJ, Freeman MP. Looking ahead. J Clin Psychiatry. 2014 Jan; 75(1):4-7. PMID: 24502858.
    View in: PubMed
  44. Freeman MP, Toth TL, Cohen LS. Assisted reproduction and risk of depressive relapse: considerations for treatment. Ann Clin Psychiatry. 2013 Nov; 25(4):283-8. PMID: 24199219.
    View in: PubMed
  45. Freeman MP. Introduction: Early career offerings. J Clin Psychiatry. 2013 Nov; 74(11):1092. PMID: 24330895.
    View in: PubMed
  46. Nyer M, Doorley J, Durham K, Yeung AS, Freeman MP, Mischoulon D. What is the role of alternative treatments in late-life depression? Psychiatr Clin North Am. 2013 Dec; 36(4):577-96. PMID: 24229658.
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  47. Freeman MP. Depression in women: new findings. J Clin Psychiatry. 2013 Oct; 74(10):1002. PMID: 24229752.
    View in: PubMed
  48. Freeman MP, Walker R, Laughren TP, Miller KK, Fava M. Female reproductive life cycle and hormones: methodology to improve clinical trials. J Clin Psychiatry. 2013 Oct; 74(10):1018-21. PMID: 24229755; PMCID: PMC4096821.
  49. Desseilles M, Witte J, Chang TE, Iovieno N, Dording C, Ashih H, Nyer M, Freeman MP, Fava M, Mischoulon D. Massachusetts General Hospital SAFER criteria for clinical trials and research. Harv Rev Psychiatry. 2013 Sep-Oct; 21(5):269-74. PMID: 24651559.
    View in: PubMed
  50. Deligiannidis KM, Freeman MP. Complementary and alternative medicine therapies for perinatal depression. Best Pract Res Clin Obstet Gynaecol. 2014 Jan; 28(1):85-95. PMID: 24041861; PMCID: PMC3992885.
  51. Freeman MP, Hirschberg AM, Wang B, Petrillo LF, Connors S, Regan S, Joffe H, Cohen LS. Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition. Maturitas. 2013 Jun; 75(2):170-4. PMID: 23602542.
    View in: PubMed
  52. Freeman MP. Pregnancy and psychiatric disorders: inherent risks and treatment decisions. J Clin Psychiatry. 2013 Apr; 74(4):373-4. PMID: 23656843.
    View in: PubMed
  53. Nelson DB, Freeman MP, Johnson NL, McIntire DD, Leveno KJ. A prospective study of postpartum depression in 17 648 parturients. J Matern Fetal Neonatal Med. 2013 Aug; 26(12):1155-61. PMID: 23421404.
    View in: PubMed
  54. Mischoulon D, Freeman MP. Omega-3 fatty acids in psychiatry. Psychiatr Clin North Am. 2013 Mar; 36(1):15-23. PMID: 23538073.
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  55. Sternfeld B, LaCroix A, Caan BJ, Dunn AL, Newton KM, Reed SD, Guthrie KA, Booth-LaForce C, Sherman KJ, Cohen L, Freeman MP, Carpenter JS, Hunt JR, Roberts M, Ensrud KE. Design and methods of a multi-site, multi-behavioral treatment trial for menopausal symptoms: the MsFLASH experience. Contemp Clin Trials. 2013 May; 35(1):25-34. PMID: 23462342; PMCID: PMC3670607.
  56. Freeman MP, Gelenberg AJ. Magnanimity. J Clin Psychiatry. 2013 Jan; 74(1):6-9. PMID: 23419221.
    View in: PubMed
  57. Byatt N, Deligiannidis KM, Freeman MP. Antidepressant use in pregnancy: a critical review focused on risks and controversies. Acta Psychiatr Scand. 2013 Feb; 127(2):94-114. PMID: 23240634; PMCID: PMC4006272.
  58. Freeman MP. Mentor in chief. J Clin Psychiatry. 2012 Aug; 73(7):923. PMID: 22901343.
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  59. Freeman MP. Can women have it all? Psychiatry and the gender gap. J Clin Psychiatry. 2012 Aug; 73(8):1139-40. PMID: 22967777.
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  60. Lin PY, Mischoulon D, Freeman MP, Matsuoka Y, Hibbeln J, Belmaker RH, Su KP. Are omega-3 fatty acids antidepressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression. Mol Psychiatry. 2012 Dec; 17(12):1161-3; author reply 1163-7. PMID: 22824812; PMCID: PMC3504139.
  61. Freeman MP. Complementary and alternative medicine for psychiatrists. Can J Psychiatry. 2012 Jul; 57(7):395-6. PMID: 22762293.
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  62. Freeman MP. The tenets of perinatal psychiatry. J Clin Psychiatry. 2012 Feb; 73(2):233-4. PMID: 22401478.
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  63. Brandon AR, Freeman MP. When she says "no" to medication: psychotherapy for antepartum depression. Curr Psychiatry Rep. 2011 Dec; 13(6):459-66. PMID: 21877161.
    View in: PubMed
  64. Freeman MP. Biopsychosocial vulnerabilities in women. J Clin Psychiatry. 2011 Nov; 72(11):1529-30. PMID: 22127195.
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  65. Freeman MP. I tried taking fish oil capsules, but they tasted fishy. Any suggestions? Harv Ment Health Lett. 2011 Oct; 28(4):5. PMID: 22125825.
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  66. Desseilles M, Witte J, Chang TE, Iovieno N, Dording CM, Ashih H, Nyer M, Freeman MP, Fava M, Mischoulon D. Assessing the adequacy of past antidepressant trials: a clinician's guide to the antidepressant treatment response questionnaire. J Clin Psychiatry. 2011 Aug; 72(8):1152-4. PMID: 21899818.
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  67. Freeman MP. Antidepressant medication treatment during pregnancy: prevalence of use, clinical implications, and alternatives. J Clin Psychiatry. 2011 Jul; 72(7):977-8. PMID: 21824457.
    View in: PubMed
  68. Freeman MP, Hibbeln JR, Silver M, Hirschberg AM, Wang B, Yule AM, Petrillo LF, Pascuillo E, Economou NI, Joffe H, Cohen LS. Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trial. Menopause. 2011 Mar; 18(3):279-84. PMID: 21037490; PMCID: PMC3195360.
  69. Freeman MP, Rapaport MH. Omega-3 fatty acids and depression: from cellular mechanisms to clinical care. J Clin Psychiatry. 2011 Feb; 72(2):258-9. PMID: 21382308.
    View in: PubMed
  70. Shivakumar G, Brandon AR, Snell PG, Santiago-Muñoz P, Johnson NL, Trivedi MH, Freeman MP. Antenatal depression: a rationale for studying exercise. Depress Anxiety. 2011 Mar; 28(3):234-42. PMID: 21394856; PMCID: PMC3079921.
  71. Freeman MP, Mischoulon D, Tedeschini E, Goodness T, Cohen LS, Fava M, Papakostas GI. Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants. J Clin Psychiatry. 2010 Jun; 71(6):682-8. PMID: 20573327.
    View in: PubMed
  72. Freeman MP, Fava M, Lake J, Trivedi MH, Wisner KL, Mischoulon D. Complementary and alternative medicine in major depressive disorder: the American Psychiatric Association Task Force report. J Clin Psychiatry. 2010 Jun; 71(6):669-81. PMID: 20573326.
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  73. Deligiannidis KM, Freeman MP. Complementary and alternative medicine for the treatment of depressive disorders in women. Psychiatr Clin North Am. 2010 Jun; 33(2):441-63. PMID: 20385346.
    View in: PubMed
  74. Cohen LS, Wang B, Nonacs R, Viguera AC, Lemon EL, Freeman MP. Treatment of mood disorders during pregnancy and postpartum. Psychiatr Clin North Am. 2010 Jun; 33(2):273-93. PMID: 20385337.
    View in: PubMed
  75. Freeman MP. Nutrition and psychiatry. Am J Psychiatry. 2010 Mar; 167(3):244-7. PMID: 20194485.
    View in: PubMed
  76. Freeman MP, Davis MF. Supportive psychotherapy for perinatal depression: preliminary data for adherence and response. Depress Anxiety. 2010; 27(1):39-45. PMID: 19691033.
    View in: PubMed
  77. Freeman MP. Women's mental health: hot topics and clinical implications. J Clin Psychiatry. 2009 Dec; 70(12):1687. PMID: 20141707.
    View in: PubMed
  78. Freeman MP. Commentaries on peer review and the evolving journal. J Clin Psychiatry. 2009 Nov; 70(11):1598. PMID: 20031099.
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  79. Freeman MP. Early career psychiatry. J Clin Psychiatry. 2009 Nov; 70(11):1571. PMID: 20031098.
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  80. Freeman MP. Postpartum depression treatment and breastfeeding. J Clin Psychiatry. 2009 Sep; 70(9):e35. PMID: 19818241.
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  81. Freeman MP. Perinatal psychiatry: the challenges of making rational treatment decisions at the interface of psychiatry and obstetrics. J Clin Psychiatry. 2009 Sep; 70(9):1311-2. PMID: 19818246.
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  82. Freeman MP. Perinatal mental health: new data regarding risk factors and treatment considerations. J Clin Psychiatry. 2009 Sep; 70(9):1289. PMID: 19818244.
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  83. Freeman MP. Location, location, location: the role of place in career development. J Clin Psychiatry. 2009 Jul; 70(7):1024-5. PMID: 19653977.
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  84. Freeman MP. Managing depression during pregnancy. J Clin Psychiatry. 2009 Jul; 70(7):e25. PMID: 19653971.
    View in: PubMed
  85. Freeman MP. An imperfect literature and evidence-based medicine. J Clin Psychiatry. 2009 Mar; 70(3):412-3. PMID: 19317958.
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  86. Freeman MP. A piece of my mind. Person, place, or thing. JAMA. 2009 Feb 11; 301(6):580. PMID: 19211457.
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  87. Freeman MP. Breastfeeding and antidepressants: clinical dilemmas and expert perspectives. J Clin Psychiatry. 2009 Feb; 70(2):291-2. PMID: 19265645.
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  88. Freeman MP. Omega-3 fatty acids in major depressive disorder. J Clin Psychiatry. 2009; 70 Suppl 5:7-11. PMID: 19909687.
    View in: PubMed
  89. Freeman MP. Complementary and Alternative Medicine (CAM): considerations for the treatment of major depressive disorder. J Clin Psychiatry. 2009; 70 Suppl 5:4-6. PMID: 19909686.
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  90. Freeman MP. This month's ECP selections. J Clin Psychiatry. 2009 Jan; 70(1):101-2. PMID: 19222981.
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  91. Gelenberg AJ, Freeman MP. JCP's circle of honor and peer reviewers. J Clin Psychiatry. 2009 Jan; 70(1):6-10. PMID: 19222979.
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  92. Freeman MP, Nolan PE, Davis MF, Anthony M, Fried K, Fankhauser M, Woosley RL, Moreno F. Pharmacokinetics of sertraline across pregnancy and postpartum. J Clin Psychopharmacol. 2008 Dec; 28(6):646-53. PMID: 19011433.
    View in: PubMed
  93. Accortt EE, Freeman MP, Allen JJ. Women and major depressive disorder: clinical perspectives on causal pathways. J Womens Health (Larchmt). 2008 Dec; 17(10):1583-90. PMID: 19049352.
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  94. Freeman MP. Early Career Psychiatrists. Introduction. This month's selections. J Clin Psychiatry. 2008 Nov; 69(11):1790-1. PMID: 19200427.
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  95. Freeman MP. Commentary Academic psychiatry: the effects of gravity on career trajectory. J Clin Psychiatry. 2008 Nov; 69(11):1791-2. PMID: 19200428.
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  96. Freeman MP. Complementary and alternative medicine for perinatal depression. J Affect Disord. 2009 Jan; 112(1-3):1-10. PMID: 18692251.
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  97. Freeman MP. Mentorship: the genuine article. J Clin Psychiatry. 2008 Aug; 69(8):1297. PMID: 18816152.
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  98. Freeman MP. Reproductive neuroscience: biology, environment, and clinical implications in women's mental health. J Clin Psychiatry. 2008 Jun; 69(6):971-2. PMID: 18683994.
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  99. Anthony M, Lee KY, Bertram CT, Abarca J, Rehfeld RA, Malone DC, Freeman M, Woosley RL. Gender and age differences in medications dispensed from a national chain drugstore. J Womens Health (Larchmt). 2008 Jun; 17(5):735-43. PMID: 18537477.
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  100. Freeman MP. Perinatal psychiatry: risk factors, treatment data, and specific challenges for clinical researchers. J Clin Psychiatry. 2008 Apr; 69(4):633-4. PMID: 18507486.
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  101. Freeman MP. Clinical trials and tribulations: perspectives on research career development. J Clin Psychiatry. 2008 Mar; 69(3):470-1. PMID: 18402498.
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  102. Freeman MP, Davis M, Sinha P, Wisner KL, Hibbeln JR, Gelenberg AJ. Omega-3 fatty acids and supportive psychotherapy for perinatal depression: a randomized placebo-controlled study. J Affect Disord. 2008 Sep; 110(1-2):142-8. PMID: 18206247.
    View in: PubMed
  103. Freeman MP. Bipolar disorder and pregnancy: risks revealed. Am J Psychiatry. 2007 Dec; 164(12):1771-3. PMID: 18056226.
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  104. Freeman MP. Screening and treatment for women with mood disorders associated with reproductive events. J Clin Psychiatry. 2007 Dec; 68(12):1946. PMID: 18162027.
    View in: PubMed
  105. Freeman MP, Sinha P. Tolerability of omega-3 fatty acid supplements in perinatal women. Prostaglandins Leukot Essent Fatty Acids. 2007 Oct-Nov; 77(3-4):203-8. PMID: 17981449.
    View in: PubMed
  106. Freeman MP. Antenatal depression: navigating the treatment dilemmas. Am J Psychiatry. 2007 Aug; 164(8):1162-5. PMID: 17671277.
    View in: PubMed
  107. Freeman MP. New data inform the risk/benefit analysis in antenatal depression. J Clin Psychiatry. 2007 Aug; 68(8):1277-8. PMID: 17854253.
    View in: PubMed
  108. Gelenberg AJ, Freeman MP. The art (and blood sport) of psychopharmacology research: who has a dog in the fight? J Clin Psychiatry. 2007 Feb; 68(2):185. PMID: 17335314.
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  109. Freeman MP. Refining the questions in women's mental health. J Clin Psychiatry. 2007 Jan; 68(1):120-1. PMID: 17284139.
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  110. Freeman MP, Hibbeln JR, Wisner KL, Davis JM, Mischoulon D, Peet M, Keck PE, Marangell LB, Richardson AJ, Lake J, Stoll AL. Omega-3 fatty acids: evidence basis for treatment and future research in psychiatry. J Clin Psychiatry. 2006 Dec; 67(12):1954-67. PMID: 17194275.
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  111. Moreno FA, McGahuey CA, Freeman MP, Delgado PL. Sex differences in depressive response during monoamine depletions in remitted depressive subjects. J Clin Psychiatry. 2006 Oct; 67(10):1618-23. PMID: 17107256.
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  112. Freeman MP. Depression: what's sex got to do with it? J Clin Psychiatry. 2006 Oct; 67(10):1610-1. PMID: 17107254.
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  113. Freeman MP, Hill R, Brumbach BH. Escitalopram for perimenopausal depression: an open-label pilot study. J Womens Health (Larchmt). 2006 Sep; 15(7):857-61. PMID: 16999641.
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  114. Freeman MP. Omega-3 fatty acids and perinatal depression: a review of the literature and recommendations for future research. Prostaglandins Leukot Essent Fatty Acids. 2006 Oct-Nov; 75(4-5):291-7. PMID: 16930971.
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  115. Keck PE, Mintz J, McElroy SL, Freeman MP, Suppes T, Frye MA, Altshuler LL, Kupka R, Nolen WA, Leverich GS, Denicoff KD, Grunze H, Duan N, Post RM. Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. Biol Psychiatry. 2006 Nov 01; 60(9):1020-2. PMID: 16814257.
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  116. Freeman MP, Freeman SA. Lithium: clinical considerations in internal medicine. Am J Med. 2006 Jun; 119(6):478-81. PMID: 16750958.
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  117. Freeman MP, Hibbeln JR, Wisner KL, Watchman M, Gelenberg AJ. An open trial of Omega-3 fatty acids for depression in pregnancy. Acta Neuropsychiatr. 2006 Feb; 18(1):21-4. PMID: 26991978.
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  118. Freeman MP, Hibbeln JR, Wisner KL, Brumbach BH, Watchman M, Gelenberg AJ. Randomized dose-ranging pilot trial of omega-3 fatty acids for postpartum depression. Acta Psychiatr Scand. 2006 Jan; 113(1):31-5. PMID: 16390366.
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  119. Freeman MP, Wright R, Watchman M, Wahl RA, Sisk DJ, Fraleigh L, Weibrecht JM. Postpartum depression assessments at well-baby visits: screening feasibility, prevalence, and risk factors. J Womens Health (Larchmt). 2005 Dec; 14(10):929-35. PMID: 16372894.
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  120. Freeman MP, Gelenberg AJ. Bipolar disorder in women: reproductive events and treatment considerations. Acta Psychiatr Scand. 2005 Aug; 112(2):88-96. PMID: 15992389.
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  121. Freeman MP. Empowering women to collaborate in their mental health care. J Clin Psychiatry. 2005 Jun; 66(6):768. PMID: 15960572.
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  122. Freeman MP, Anthony M. Focus on women's mental health. J Clin Psychiatry. 2004 Sep; 65(9):1164-5. PMID: 15367041.
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  123. Freeman MP. Testosterone supplementation in women: prescribing practices in one community. J Womens Health (Larchmt). 2004 Mar; 13(2):239-40. PMID: 15072739.
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  124. Freeman MP, Helgason C, Hill RA. Selected integrative medicine treatments for depression: considerations for women. J Am Med Womens Assoc (1972). 2004; 59(3):216-24. PMID: 15354376.
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  125. Gnanadesikan M, Freeman MP, Gelenberg AJ. Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder. Bipolar Disord. 2003 Jun; 5(3):203-16. PMID: 12780874.
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  126. Freeman MP, Freeman SA. Treatment of leuprolide-induced depression with intramuscular testosterone: a case report. J Clin Psychiatry. 2003 Mar; 64(3):341-3. PMID: 12716284.
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  127. Freeman MP, Gracious BL, Wisner KL. Pregnancy outcomes in schizophrenia. Am J Psychiatry. 2002 Sep; 159(9):1609; author reply 1609. PMID: 12202294.
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  128. Freeman MP, Smith KW, Freeman SA, McElroy SL, Kmetz GE, Wright R, Keck PE. The impact of reproductive events on the course of bipolar disorder in women. J Clin Psychiatry. 2002 Apr; 63(4):284-7. PMID: 12004800.
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  129. Kumet R, Freeman MP. Clozapine and tardive dyskinesia. J Clin Psychiatry. 2002 Feb; 63(2):167-8. PMID: 11874222.
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  130. Freeman MP, Freeman SA, McElroy SL. The comorbidity of bipolar and anxiety disorders: prevalence, psychobiology, and treatment issues. J Affect Disord. 2002 Feb; 68(1):1-23. PMID: 11869778.
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  131. Freeman MP, Keck PE, McElroy SL. Postpartum depression with bipolar disorder. Am J Psychiatry. 2001 Apr; 158(4):652. PMID: 11282711.
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  132. Freeman MP. Omega-3 fatty acids in psychiatry: a review. Ann Clin Psychiatry. 2000 Sep; 12(3):159-65. PMID: 10984006.
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  133. Freeman MP, McElroy SL. Clinical picture and etiologic models of mixed states. Psychiatr Clin North Am. 1999 Sep; 22(3):535-46, vii. PMID: 10550854.
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  134. Stoll AL, Severus WE, Freeman MP, Rueter S, Zboyan HA, Diamond E, Cress KK, Marangell LB. Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Arch Gen Psychiatry. 1999 May; 56(5):407-12. PMID: 10232294.
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  135. Freeman MP. Valproate with lithium and carbamazepine in bipolar disorder. Am J Psychiatry. 1999 May; 156(5):810-1. PMID: 10327939.
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  136. Freeman MP, Stoll AL. Mood stabilizer combinations: a review of safety and efficacy. Am J Psychiatry. 1998 Jan; 155(1):12-21. PMID: 9433333.
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