Harvard Catalyst Profiles

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K Frank Austen, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Weiler CR, Austen KF, Akin C, Barkoff MS, Bernstein JA, Bonadonna P, Butterfield JH, Carter M, Fox CC, Maitland A, Pongdee T, Mustafa SS, Ravi A, Tobin MC, Vliagoftis H, Schwartz LB. AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management. J Allergy Clin Immunol. 2019 10; 144(4):883-896. PMID: 31476322.
  2. Kanaoka Y, Austen KF. Roles of cysteinyl leukotrienes and their receptors in immune cell-related functions. Adv Immunol. 2019; 142:65-84. PMID: 31296303.
  3. Leyva-Castillo JM, Galand C, Kam C, Burton O, Gurish M, Musser MA, Goldsmith JD, Hait E, Nurko S, Brombacher F, Dong C, Finkelman FD, Lee RT, Ziegler S, Chiu I, Austen KF, Geha RS. Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion. Immunity. 2019 05 21; 50(5):1262-1275.e4. PMID: 31027995.
  4. Duah E, Teegala LR, Kondeti V, Adapala RK, Keshamouni VG, Kanaoka Y, Austen KF, Thodeti CK, Paruchuri S. Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis. Proc Natl Acad Sci U S A. 2019 01 02; 116(1):199-204. PMID: 30559191.
    Citations:    Fields:    
  5. Austen KF. Mentoring: An art and a responsibility. J Allergy Clin Immunol. 2018 03; 141(3):880-881. PMID: 29382599.
    Citations:    Fields:    
  6. Austen KF, Gurish MF. Resolution of a human mast cell development conundrum. Blood. 2017 10 19; 130(16):1777-1778. PMID: 29051149.
    Citations: 1     Fields:    Translation:HumansCells
  7. Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Schwartz LB, Broesby-Olsen S, Bindslev-Jensen C, Kovanen PT, Galli SJ, Austen KF, Arber DA, Horny HP, Arock M, Metcalfe DD. Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future. Cancer Res. 2017 03 15; 77(6):1261-1270. PMID: 28254862.
    Citations: 10     Fields:    Translation:Humans
  8. von Moltke J, O'Leary CE, Barrett NA, Kanaoka Y, Austen KF, Locksley RM. Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med. 2017 01; 214(1):27-37. PMID: 28011865.
    Citations: 14     Fields:    Translation:AnimalsCells
  9. McGovern T, Goldberger M, Chen M, Allard B, Hamamoto Y, Kanaoka Y, Austen KF, Powell WS, Martin JG. CysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma. J Immunol. 2016 07 01; 197(1):266-77. PMID: 27226094.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  10. Bankova LG, Lai J, Yoshimoto E, Boyce JA, Austen KF, Kanaoka Y, Barrett NA. Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):6242-7. PMID: 27185938.
    Citations: 8     Fields:    Translation:AnimalsCells
  11. Dwyer DF, Barrett NA, Austen KF. Expression profiling of constitutive mast cells reveals a unique identity within the immune system. Nat Immunol. 2016 Jul; 17(7):878-87. PMID: 27135604.
    Citations: 26     Fields:    Translation:AnimalsCells
  12. Austen K, Ringer P, Mehlich A, Chrostek-Grashoff A, Kluger C, Klingner C, Sabass B, Zent R, Rief M, Grashoff C. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015 Dec; 17(12):1597-606. PMID: 26523364.
    Citations: 46     Fields:    Translation:AnimalsCells
  13. Barrett NA, Austen KF. Licensed to Ill: IL-9 Generation in Immature Mast Cells Permits Food-Elicited Anaphylaxis. Immunity. 2015 Oct 20; 43(4):626-8. PMID: 26488812.
    Citations:    Fields:    Translation:HumansAnimalsCells
  14. Bankova LG, Dwyer DF, Liu AY, Austen KF, Gurish MF. Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice. Mucosal Immunol. 2015 May; 8(3):596-606. PMID: 25291985.
    Citations: 9     Fields:    Translation:AnimalsCells
  15. Dwyer DF, Woodruff MC, Carroll MC, Austen KF, Gurish MF. B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake. J Immunol. 2014 Jul 15; 193(2):529-39. PMID: 24928991.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
  16. Austen KF. K. Frank Austen. Boston, Mass., USA. Chem Immunol Allergy. 2014; 100:340-1. PMID: 24925415.
    Citations:    Fields:    Translation:Humans
  17. Bankova LG, Lezcano C, Pejler G, Stevens RL, Murphy GF, Austen KF, Gurish MF. Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions. J Immunol. 2014 Mar 15; 192(6):2812-20. PMID: 24523504.
    Citations: 7     Fields:    Translation:AnimalsCells
  18. Parsons MW, Li L, Wallace AM, Lee MJ, Katz HR, Fernandez JM, Saijo S, Iwakura Y, Austen KF, Kanaoka Y, Barrett NA. Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization. J Immunol. 2014 Feb 15; 192(4):1361-71. PMID: 24453247.
    Citations: 13     Fields:    Translation:AnimalsCells
  19. Kanaoka Y, Maekawa A, Austen KF. Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. J Biol Chem. 2013 Apr 19; 288(16):10967-72. PMID: 23504326.
    Citations: 41     Fields:    Translation:Animals
  20. Bartnikas LM, Gurish MF, Burton OT, Leisten S, Janssen E, Oettgen HC, Beaupr├ę J, Lewis CN, Austen KF, Schulte S, Hornick JL, Geha RS, Oyoshi MK. Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis. J Allergy Clin Immunol. 2013 Feb; 131(2):451-60.e1-6. PMID: 23374269.
    Citations: 20     Fields:    Translation:AnimalsCells
  21. Liu AY, Dwyer DF, Jones TG, Bankova LG, Shen S, Katz HR, Austen KF, Gurish MF. Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6. J Immunol. 2013 Feb 15; 190(4):1758-66. PMID: 23319739.
    Citations: 6     Fields:    Translation:AnimalsCells
  22. Barrett NA, Fernandez JM, Maekawa A, Xing W, Li L, Parsons MW, Austen KF, Kanaoka Y. Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation. J Immunol. 2012 Nov 01; 189(9):4556-65. PMID: 23002438.
    Citations: 12     Fields:    Translation:AnimalsCells
  23. Gurish MF, Austen KF. Developmental origin and functional specialization of mast cell subsets. Immunity. 2012 Jul 27; 37(1):25-33. PMID: 22840841.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  24. Oyoshi MK, He R, Kanaoka Y, ElKhal A, Kawamoto S, Lewis CN, Austen KF, Geha RS. Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4992-7. PMID: 22416124.
    Citations: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  25. Katz HR, Austen KF. Mast cell deficiency, a game of kit and mouse. Immunity. 2011 Nov 23; 35(5):668-70. PMID: 22118523.
    Citations: 12     Fields:    
  26. Petersen B, Austen KF, Bloch KD, Hotta Y, Ichinose F, Kanaoka Y, Zapol WM. Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice. Anesthesiology. 2011 Oct; 115(4):804-11. PMID: 21934409.
    Citations: 2     Fields:    Translation:AnimalsCells
  27. Xing W, Austen KF, Gurish MF, Jones TG. Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue. Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34):14210-5. PMID: 21825171.
    Citations: 34     Fields:    Translation:AnimalsCellsPHPublic Health
  28. Saino H, Ukita Y, Ago H, Irikura D, Nisawa A, Ueno G, Yamamoto M, Kanaoka Y, Lam BK, Austen KF, Miyano M. The catalytic architecture of leukotriene C4 synthase with two arginine residues. J Biol Chem. 2011 May 06; 286(18):16392-401. PMID: 21454538.
    Citations: 8     Fields:    Translation:HumansCells
  29. Barrett NA, Rahman OM, Fernandez JM, Parsons MW, Xing W, Austen KF, Kanaoka Y. Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes. J Exp Med. 2011 Mar 14; 208(3):593-604. PMID: 21357742.
    Citations: 61     Fields:    Translation:AnimalsCells
  30. Younan G, Suber F, Xing W, Shi T, Kunori Y, Abrink M, Pejler G, Schlenner SM, Rodewald HR, Moore FD, Stevens RL, Adachi R, Austen KF, Gurish MF. The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5. J Immunol. 2010 Dec 15; 185(12):7681-90. PMID: 21076070.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  31. Jones TG, Finkelman FD, Austen KF, Gurish MF. T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57BL/6 mice. J Immunol. 2010 Aug 01; 185(3):1804-11. PMID: 20601599.
    Citations: 6     Fields:    Translation:AnimalsCells
  32. Maekawa A, Xing W, Austen KF, Kanaoka Y. GPR17 regulates immune pulmonary inflammation induced by house dust mites. J Immunol. 2010 Aug 01; 185(3):1846-54. PMID: 20574000.
    Citations: 13     Fields:    Translation:AnimalsCells
  33. Collington SJ, Hallgren J, Pease JE, Jones TG, Rollins BJ, Westwick J, Austen KF, Williams TJ, Gurish MF, Weller CL. The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo. J Immunol. 2010 Jun 01; 184(11):6114-23. PMID: 20427772.
    Citations: 20     Fields:    Translation:AnimalsCells
  34. Jones TG, Hallgren J, Humbles A, Burwell T, Finkelman FD, Alcaide P, Austen KF, Gurish MF. Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. J Immunol. 2009 Oct 15; 183(8):5251-60. PMID: 19783672.
    Citations: 31     Fields:    Translation:AnimalsCells
  35. Barrett NA, Austen KF. Innate cells and T helper 2 cell immunity in airway inflammation. Immunity. 2009 Sep 18; 31(3):425-37. PMID: 19766085.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  36. Austen KF, Maekawa A, Kanaoka Y, Boyce JA. The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications. J Allergy Clin Immunol. 2009 Sep; 124(3):406-14; quiz 415-6. PMID: 19647860.
    Citations: 26     Fields:    Translation:HumansAnimals
  37. Maekawa A, Balestrieri B, Austen KF, Kanaoka Y. GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4. Proc Natl Acad Sci U S A. 2009 Jul 14; 106(28):11685-90. PMID: 19561298.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  38. Barrett NA, Maekawa A, Rahman OM, Austen KF, Kanaoka Y. Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J Immunol. 2009 Jan 15; 182(2):1119-28. PMID: 19124755.
    Citations: 83     Fields:    Translation:AnimalsCells
  39. Blossom DB, Kallen AJ, Patel PR, Elward A, Robinson L, Gao G, Langer R, Perkins KM, Jaeger JL, Kurkjian KM, Jones M, Schillie SF, Shehab N, Ketterer D, Venkataraman G, Kishimoto TK, Shriver Z, McMahon AW, Austen KF, Kozlowski S, Srinivasan A, Turabelidze G, Gould CV, Arduino MJ, Sasisekharan R. Outbreak of adverse reactions associated with contaminated heparin. N Engl J Med. 2008 Dec 18; 359(25):2674-84. PMID: 19052120.
    Citations: 51     Fields:    Translation:HumansPHPublic Health
  40. Maekawa A, Kanaoka Y, Xing W, Austen KF. Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors. Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43):16695-700. PMID: 18931305.
    Citations: 43     Fields:    Translation:Animals
  41. Kishimoto TK, Viswanathan K, Ganguly T, Elankumaran S, Smith S, Pelzer K, Lansing JC, Sriranganathan N, Zhao G, Galcheva-Gargova Z, Al-Hakim A, Bailey GS, Fraser B, Roy S, Rogers-Cotrone T, Buhse L, Whary M, Fox J, Nasr M, Dal Pan GJ, Shriver Z, Langer RS, Venkataraman G, Austen KF, Woodcock J, Sasisekharan R. Contaminated heparin associated with adverse clinical events and activation of the contact system. N Engl J Med. 2008 Jun 05; 358(23):2457-67. PMID: 18434646.
    Citations: 116     Fields:    Translation:HumansAnimalsPHPublic Health
  42. Austen KF. The cysteinyl leukotrienes: where do they come from? What are they? Where are they going? Nat Immunol. 2008 Feb; 9(2):113-5. PMID: 18204420.
    Citations: 10     Fields:    Translation:HumansAnimals
  43. Austen KF. Doing what I like. Annu Rev Immunol. 2008; 26:1-28. PMID: 17877459.
    Citations:    Fields:    Translation:Cells
  44. Hallgren J, Jones TG, Abonia JP, Xing W, Humbles A, Austen KF, Gurish MF. Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors. Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20478-83. PMID: 18077323.
    Citations: 40     Fields:    Translation:AnimalsCells
  45. Zhou JS, Xing W, Friend DS, Austen KF, Katz HR. Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis. J Exp Med. 2007 Nov 26; 204(12):2797-802. PMID: 17998392.
    Citations: 62     Fields:    Translation:AnimalsCells
  46. Ago H, Kanaoka Y, Irikura D, Lam BK, Shimamura T, Austen KF, Miyano M. Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis. Nature. 2007 Aug 02; 448(7153):609-12. PMID: 17632548.
    Citations: 49     Fields:    Translation:HumansCells
  47. Austen KF. Additional functions for the cysteinyl leukotrienes recognized through studies of inflammatory processes in null strains. Prostaglandins Other Lipid Mediat. 2007 May; 83(3):182-7. PMID: 17481553.
    Citations: 2     Fields:    Translation:Animals
  48. Austen KF. The National Institute of Allergy and Infectious Diseases' Asthma and Allergic Disease Centers: a personal commentary. J Allergy Clin Immunol. 2007 Jan; 119(1):34-5. PMID: 17141857.
    Citations: 1     Fields:    
  49. Abonia JP, Hallgren J, Jones T, Shi T, Xu Y, Koni P, Flavell RA, Boyce JA, Austen KF, Gurish MF. Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung. Blood. 2006 Sep 01; 108(5):1588-94. PMID: 16670268.
    Citations: 41     Fields:    Translation:AnimalsCells
  50. Kim DC, Hsu FI, Barrett NA, Friend DS, Grenningloh R, Ho IC, Al-Garawi A, Lora JM, Lam BK, Austen KF, Kanaoka Y. Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation. J Immunol. 2006 Apr 01; 176(7):4440-8. PMID: 16547282.
    Citations: 52     Fields:    Translation:AnimalsCells
  51. Chen M, Lam BK, Kanaoka Y, Nigrovic PA, Audoly LP, Austen KF, Lee DM. Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. J Exp Med. 2006 Apr 17; 203(4):837-42. PMID: 16567388.
    Citations: 94     Fields:    Translation:AnimalsCells
  52. Arinobu Y, Iwasaki H, Gurish MF, Mizuno S, Shigematsu H, Ozawa H, Tenen DG, Austen KF, Akashi K. Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18105-10. PMID: 16330751.
    Citations: 95     Fields:    Translation:AnimalsCells
  53. Boyce JA, Austen KF. No audible wheezing: nuggets and conundrums from mouse asthma models. J Exp Med. 2005 Jun 20; 201(12):1869-73. PMID: 15967817.
    Citations: 26     Fields:    Translation:AnimalsCells
  54. Abonia JP, Friend DS, Austen WG, Moore FD, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, Gurish MF. Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle. J Immunol. 2005 Jun 01; 174(11):7285-91. PMID: 15905575.
    Citations: 29     Fields:    Translation:AnimalsCells
  55. Zhou JS, Friend DS, Lee DM, Li L, Austen KF, Katz HR. gp49B1 deficiency is associated with increases in cytokine and chemokine production and severity of proliferative synovitis induced by anti-type II collagen mAb. Eur J Immunol. 2005 May; 35(5):1530-8. PMID: 15827966.
    Citations: 8     Fields:    Translation:AnimalsCells
  56. Abonia JP, Austen KF, Rollins BJ, Joshi SK, Flavell RA, Kuziel WA, Koni PA, Gurish MF. Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2. Blood. 2005 Jun 01; 105(11):4308-13. PMID: 15705791.
    Citations: 32     Fields:    Translation:AnimalsCells
  57. Austen KF. The mast cell and the cysteinyl leukotrienes. Novartis Found Symp. 2005; 271:166-75; discussion 176-8, 198-9. PMID: 16605134.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  58. Schmidt-Krey I, Kanaoka Y, Mills DJ, Irikura D, Haase W, Lam BK, Austen KF, K├╝hlbrandt W. Human leukotriene C(4) synthase at 4.5 A resolution in projection. Structure. 2004 Nov; 12(11):2009-14. PMID: 15530365.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  59. Austen KF. Acceptance of the Kober Medal: It only gets better. J Clin Invest. 2004 Oct; 114(8):1177. PMID: 15489967.
    Citations:    Fields:    Translation:Humans
  60. Beller TC, Maekawa A, Friend DS, Austen KF, Kanaoka Y. Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice. J Biol Chem. 2004 Oct 29; 279(44):46129-34. PMID: 15328359.
    Citations: 40     Fields:    Translation:AnimalsCells
  61. Bagga S, Price KS, Lin DA, Friend DS, Austen KF, Boyce JA. Lysophosphatidic acid accelerates the development of human mast cells. Blood. 2004 Dec 15; 104(13):4080-7. PMID: 15319282.
    Citations: 18     Fields:    Translation:HumansCells
  62. Sloane DE, Tedla N, Awoniyi M, Macglashan DW, Borges L, Austen KF, Arm JP. Leukocyte immunoglobulin-like receptors: novel innate receptors for human basophil activation and inhibition. Blood. 2004 Nov 01; 104(9):2832-9. PMID: 15242876.
    Citations: 20     Fields:    Translation:HumansCells
  63. Beller TC, Friend DS, Maekawa A, Lam BK, Austen KF, Kanaoka Y. Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):3047-52. PMID: 14970333.
    Citations: 36     Fields:    Translation:AnimalsCells
  64. Zhou JS, Friend DS, Feldweg AM, Daheshia M, Li L, Austen KF, Katz HR. Prevention of lipopolysaccharide-induced microangiopathy by gp49B1: evidence for an important role for gp49B1 expression on neutrophils. J Exp Med. 2003 Oct 20; 198(8):1243-51. PMID: 14557414.
    Citations: 7     Fields:    Translation:AnimalsCells
  65. Mellor EA, Frank N, Soler D, Hodge MR, Lora JM, Austen KF, Boyce JA. Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11589-93. PMID: 13679572.
    Citations: 36     Fields:    Translation:HumansCells
  66. Feldweg AM, Friend DS, Zhou JS, Kanaoka Y, Daheshia M, Li L, Austen KF, Katz HR. gp49B1 suppresses stem cell factor-induced mast cell activation-secretion and attendant inflammation in vivo. Eur J Immunol. 2003 Aug; 33(8):2262-8. PMID: 12884301.
    Citations: 9     Fields:    Translation:AnimalsCells
  67. Arm JP, Austen KF. Leukotriene receptors and aspirin sensitivity. N Engl J Med. 2002 Nov 07; 347(19):1524-6. PMID: 12421897.
    Citations: 8     Fields:    Translation:HumansCells
  68. Lam BK, Austen KF. Leukotriene C4 synthase: a pivotal enzyme in cellular biosynthesis of the cysteinyl leukotrienes. Prostaglandins Other Lipid Mediat. 2002 Aug; 68-69:511-20. PMID: 12432940.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  69. Gurish MF, Humbles A, Tao H, Finkelstein S, Boyce JA, Gerard C, Friend DS, Austen KF. CCR3 is required for tissue eosinophilia and larval cytotoxicity after infection with Trichinella spiralis. J Immunol. 2002 Jun 01; 168(11):5730-6. PMID: 12023373.
    Citations: 22     Fields:    Translation:AnimalsCells
  70. Maekawa A, Austen KF, Kanaoka Y. Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses. J Biol Chem. 2002 Jun 07; 277(23):20820-4. PMID: 11932261.
    Citations: 37     Fields:    Translation:AnimalsCells
  71. Mellor EA, Austen KF, Boyce JA. Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists. J Exp Med. 2002 Mar 04; 195(5):583-92. PMID: 11877481.
    Citations: 45     Fields:    Translation:Cells
  72. Castells M, Austen KF. Mastocytosis: mediator-related signs and symptoms. Int Arch Allergy Immunol. 2002 Feb; 127(2):147-52. PMID: 11919427.
    Citations: 17     Fields:    Translation:HumansCells
  73. Seymour ML, Rak S, Aberg D, Riise GC, Penrose JF, Kanaoka Y, Austen KF, Holgate ST, Sampson AP. Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics. Am J Respir Crit Care Med. 2001 Dec 01; 164(11):2051-6. PMID: 11739134.
    Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  74. Gurish MF, Tao H, Abonia JP, Arya A, Friend DS, Parker CM, Austen KF. Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing. J Exp Med. 2001 Nov 05; 194(9):1243-52. PMID: 11696590.
    Citations: 51     Fields:    Translation:AnimalsCells