Harvard Catalyst Profiles

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Mustafa Sahin, Ph.D., M.D.

Concepts

This page shows the publications Mustafa Sahin has written about Signal Transduction.
Connection Strength

1.081
  1. Abnormal mTOR Activation in Autism. Annu Rev Neurosci. 2018 07 08; 41:1-23.
    View in: PubMed
    Score: 0.137
  2. Using tuberous sclerosis complex to understand the impact of MTORC1 signaling on mitochondrial dynamics and mitophagy in neurons. Autophagy. 2017 Apr 03; 13(4):754-756.
    View in: PubMed
    Score: 0.128
  3. The neurology of mTOR. Neuron. 2014 Oct 22; 84(2):275-91.
    View in: PubMed
    Score: 0.109
  4. Targeted treatment trials for tuberous sclerosis and autism: no longer a dream. Curr Opin Neurobiol. 2012 Oct; 22(5):895-901.
    View in: PubMed
    Score: 0.092
  5. Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex. Curr Opin Neurol. 2011 Apr; 24(2):106-13.
    View in: PubMed
    Score: 0.085
  6. TSC1/TSC2 signaling in the CNS. FEBS Lett. 2011 Apr 06; 585(7):973-80.
    View in: PubMed
    Score: 0.085
  7. Tau: A Novel Entry Point for mTOR-Based Treatments in Autism Spectrum Disorder? Neuron. 2020 05 06; 106(3):359-361.
    View in: PubMed
    Score: 0.040
  8. Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice. Hum Mol Genet. 2019 09 01; 28(17):2952-2964.
    View in: PubMed
    Score: 0.038
  9. Genetic Etiologies, Diagnosis, and Treatment of Tuberous Sclerosis Complex. Annu Rev Genomics Hum Genet. 2019 08 31; 20:217-240.
    View in: PubMed
    Score: 0.037
  10. The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex. J Neurosci. 2015 Jul 29; 35(30):10762-72.
    View in: PubMed
    Score: 0.029
  11. A vascular model of Tsc1 deficiency accelerates renal tumor formation with accompanying hemangiosarcomas. Mol Cancer Res. 2015 Mar; 13(3):548-55.
    View in: PubMed
    Score: 0.028
  12. EphA7 signaling guides cortical dendritic development and spine maturation. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):4994-9.
    View in: PubMed
    Score: 0.026
  13. Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1. Hum Mol Genet. 2014 Jul 15; 23(14):3865-74.
    View in: PubMed
    Score: 0.026
  14. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. Nat Cell Biol. 2013 Oct; 15(10):1186-96.
    View in: PubMed
    Score: 0.025
  15. A genetic model to dissect the role of Tsc-mTORC1 in neuronal cultures. Methods Mol Biol. 2012; 821:393-405.
    View in: PubMed
    Score: 0.022
  16. Eph receptor and mTOR pathway crosstalk: implications for cancer. . 2010 Jun 01; 9(11):2053-4.
    View in: PubMed
    Score: 0.020
  17. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4153-8.
    View in: PubMed
    Score: 0.020
  18. Tsc2-Rheb signaling regulates EphA-mediated axon guidance. Nat Neurosci. 2010 Feb; 13(2):163-72.
    View in: PubMed
    Score: 0.020
  19. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science. 2008 Nov 07; 322(5903):963-6.
    View in: PubMed
    Score: 0.018
  20. Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function. J Neurosci. 2008 May 21; 28(21):5422-32.
    View in: PubMed
    Score: 0.017
  21. Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. Mol Cell. 2008 Mar 14; 29(5):541-51.
    View in: PubMed
    Score: 0.017
  22. Cardiac rhabdomyoma in tuberous sclerosis: hyperactive Erk signaling. Int J Cardiol. 2009 Feb 06; 132(1):145-7.
    View in: PubMed
    Score: 0.017
  23. Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron. 2005 Apr 21; 46(2):205-17.
    View in: PubMed
    Score: 0.014
  24. EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin. Cell. 2001 Apr 20; 105(2):233-44.
    View in: PubMed
    Score: 0.011
  25. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. Neurobiol Dis. 2018 03; 111:91-101.
    View in: PubMed
    Score: 0.008
  26. RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. J Clin Invest. 2014 Jun; 124(6):2774-84.
    View in: PubMed
    Score: 0.007
  27. Murine Glut-1 transporter haploinsufficiency: postnatal deceleration of brain weight and reactive astrocytosis. Neurobiol Dis. 2009 Oct; 36(1):60-9.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.